Publications

Abstract

One of the most controversial hypotheses in cognitive science is the Chomskyan evolutionary conjecture that language arose instantaneously in humans through a single mutation. Here we analyze the evolutionary dynamics implied by this hypothesis, which has never been formalized before. The hypothesis supposes the emergence and fixation of a single mutant (capable of the syntactic operation Merge) during a narrow historical window as a result of frequency-independent selection under a huge fitness advantage in a population of an effective size no larger than ~15 000 individuals. We examine this proposal by combining diffusion analysis and extreme value theory to derive a probabilistic formulation of its dynamics. We find that although a macro-mutation is much more likely to go to fixation if it occurs, it is much more unlikely a priori than multiple mutations with smaller fitness effects. The most likely scenario is therefore one where a medium number of mutations with medium fitness effects accumulate. This precise analysis of the probability of mutations occurring and going to fixation has not been done previously in the context of the evolution of language. Our results cast doubt on any suggestion that evolutionary reasoning provides an independent rationale for a single-mutant theory of language.

Abstract

The present study extends neuro-imaging into conversation through studying dialogue comprehension. Conversation entails rapid responses, with negative semiotics for delay. We explored how expectations about the valence of the forthcoming response develop during the silence before the response and whether negative responses have mainly cognitive or social-emotional consequences. EEG-participants listened to questions from a spontaneous spoken corpus, cross-spliced with short/long gaps and “yes”/“no” responses. Preceding contexts biased listeners to expect the eventual response, which was hypothesised to translate to expectations for a shorter or longer gap. “No” responses showed a trend towards an early positivity, suggesting socio-emotional consequences. Within the long gap, expecting a “yes” response led to an earlier negativity, as well as a trend towards stronger theta-oscillations, after 300 milliseconds. This suggests that listeners anticipate/predict “yes” responses to come earlier than “no” responses, showing strong sensitivities to timing, which presumably promote hastening the pace of verbal interaction.

Abstract

Conversation is generally characterized by smooth transitions between turns, with only very short gaps. This entails that responders often begin planning their response before the ongoing turn is finished. However, controversy exists about whether they start planning as early as they can, to make sure they respond on time, or as late as possible, to minimize the overlap between comprehension and production planning. Two earlier EEG studies have found neural correlates of response planning (positive ERP and alpha decrease) as soon as listeners could start planning their response, already midway through the current turn. However, in these studies, the questions asked were highly controlled with respect to the position where planning could start (e.g., very early) and required short and easy responses. The present study measured participants' EEG while an experimenter interviewed them in a spontaneous interaction. Coding the questions in the interviews showed that, under these natural circumstances, listeners can, in principle, start planning a response relatively early, on average after only about one third of the question has passed. Furthermore, ERP results showed a large positivity, interpreted before as an early neural signature of response planning, starting about half a second after the start of the word that allowed listeners to start planning a response. A second neural signature of response planning, an alpha decrease, was not replicated as reliably. In conclusion, listeners appear to start planning their response early during the ongoing turn, also under natural circumstances, presumably in order to keep the gap between turns short and respond on time. These results have several important implications for turn-taking theories, which need to explain how interlocutors deal with the overlap between comprehension and production, how they manage to come in on time, and the sources that lead to variability between conversationalists in the start of planning.

Abstract

This study addresses the question whether prosodic information can affect the choice for a syntactic analysis in auditory sentence processing. We manipulated the prosody (in the form of a prosodic break; PB) of locally ambiguous Dutch sentences to favor one of two interpretations. The experimental items contained two different types of so-called control verbs (subject and object control) in the matrix clause and were syntactically disambiguated by a transitive or by an intransitive verb. In Experiment 1, we established the default off-line preference of the items for a transitive or an intransitive disambiguating verb with a visual and an auditory fragment completion test. The results suggested that subject- and object-control verbs differently affect the syntactic structure that listeners expect. In Experiment 2, we investigated these two types of verbs separately in an on-line ERP study. Consistent with the literature, the PB elicited a closure positive shift. Furthermore, in subject-control items, an N400 effect for intransitive relative to transitive disambiguating verbs was found, both for sentences with and for sentences without a PB. This result suggests that the default preference for subject-control verbs goes in the same direction as the effect of the PB. In object-control items, an N400 effect for intransitive relative to transitive disambiguating verbs was found for sentences with a PB but no effect in the absence of a PB. This indicates that a PB can affect the syntactic analysis that listeners pursue.

Abstract

How do we decide where events begin and end? Like the ECOM clips, this questionnaire is designed to investigate how a language divides and/or integrates complex scenarios into sub-events and macro-events. The questionnaire focuses on events of motion, caused state change (e.g., breaking), and transfer (e.g., giving). It provides a checklist of scenarios that give insight into where a language “draws the line” in event integration, based on known cross-linguistic differences.

Abstract

How do we decide where events begin and end? In some languages it makes sense to say something like Dan broke the plate, but in other languages it is necessary to treat this action as a complex scenario composed of separate stages (Dan dropped the plate and then the plate broke). This document introduces issues concerning the linguistic and cognitive representations of event complexity and integration, and provides an overview of tasks that are relevant to this topic, including the ECOM clips, the Questionnaire on Event integration, and the Questionnaire on motion lexicalisation and motion description.

Abstract

How do we decide where events begin and end? In some languages it makes sense to say something like Dan broke the plate, but in other languages it is necessary to treat this action as a complex scenario composed of separate stages (Dan dropped the plate and then the plate broke). The “Event Complexity” (ECOM) clips are designed to explore how languages differ in dividing and/or integrating complex scenarios into sub-events and macro-events. The stimuli consist of animated clips of geometric shapes that participate in different scenarios (e.g., a circle “hits” a triangle and “breaks” it). Consultants are asked to describe the scenes, and then to comment on possible alternative descriptions.

Abstract

Disfluencies, like 'uh', have been shown to help listeners anticipate reference to low-frequency words. The associative account of this 'disfluency bias' proposes that listeners learn to associate disfluency with low-frequency referents based on prior exposure to non-arbitrary disfluency distributions (i.e., greater probability of low-frequency words after disfluencies). However, there is limited evidence for listeners actually tracking disfluency distributions online. The present experiments are the first to show that adult listeners, exposed to a typical or more atypical disfluency distribution (i.e., hearing a talker unexpectedly say uh before high-frequency words), flexibly adjust their predictive strategies to the disfluency distribution at hand (e.g., learn to predict high-frequency referents after disfluency). However, when listeners were presented with the same atypical disfluency distribution but produced by a non-native speaker, no adjustment was observed. This suggests pragmatic inferences can modulate distributional learning, revealing the flexibility of, and constraints on, distributional learning in incremental language comprehension.

Abstract

Speakers adjust their voice when talking in noise, which is known as Lombard speech. These acoustic adjustments facilitate speech comprehension in noise relative to plain speech (i.e., speech produced in quiet). However, exactly which characteristics of Lombard speech drive this intelligibility benefit in noise remains unclear. This study assessed the contribution of enhanced amplitude modulations to the Lombard speech intelligibility benefit by demonstrating that (1) native speakers of Dutch in the Nijmegen Corpus of Lombard Speech (NiCLS) produce more pronounced amplitude modulations in noise vs. in quiet; (2) more enhanced amplitude modulations correlate positively with intelligibility in a speech-in-noise perception experiment; (3) transplanting the amplitude modulations from Lombard speech onto plain speech leads to an intelligibility improvement, suggesting that enhanced amplitude modulations in Lombard speech contribute towards intelligibility in noise. Results are discussed in light of recent neurobiological models of speech perception with reference to neural oscillators phase-locking to the amplitude modulations in speech, guiding the processing of speech.

Abstract

Spoken words are highly variable and therefore listeners interpret speech sounds relative to the surrounding acoustic context, such as the speech rate of a preceding sentence. For instance, a vowel midway between short /ɑ/ and long /a:/ in Dutch is perceived as short /ɑ/ in the context of preceding slow speech, but as long /a:/ if preceded by a fast context. Despite the well-established influence of visual articulatory cues on speech comprehension, it remains unclear whether visual cues to speech rate also influence subsequent spoken word recognition. In two ‘Go Fish’-like experiments, participants were presented with audio-only (auditory speech + fixation cross), visual-only (mute videos of talking head), and audiovisual (speech + videos) context sentences, followed by ambiguous target words containing vowels midway between short /ɑ/ and long /a:/. In Experiment 1, target words were always presented auditorily, without visual articulatory cues. Although the audio-only and audiovisual contexts induced a rate effect (i.e., more long /a:/ responses after fast contexts), the visual-only condition did not. When, in Experiment 2, target words were presented audiovisually, rate effects were observed in all three conditions, including visual-only. This suggests that visual cues to speech rate in a context sentence influence the perception of following visual target cues (e.g., duration of lip aperture), which at an audiovisual integration stage bias participants’ target categorization responses. These findings contribute to a better understanding of how what we see influences what we hear.

Abstract

Two fundamental properties of perception are selective attention and perceptual contrast, but how these two processes interact remains unknown. Does an attended stimulus history exert a larger contrastive influence on the perception of a following target than unattended stimuli? Dutch listeners categorized target sounds with a reduced prefix “ge-” marking tense (e.g., ambiguous between gegaan-gaan “gone-go”). In ‘single talker’ Experiments 1–2, participants perceived the reduced syllable (reporting gegaan) when the target was heard after a fast sentence, but not after a slow sentence (reporting gaan). In ‘selective attention’ Experiments 3–5, participants listened to two simultaneous sentences from two different talkers, followed by the same target sounds, with instructions to attend only one of the two talkers. Critically, the speech rates of attended and unattended talkers were found to equally influence target perception – even when participants could watch the attended talker speak. In fact, participants’ target perception in ‘selective attention’ Experiments 3–5 did not differ from participants who were explicitly instructed to divide their attention equally across the two talkers (Experiment 6). This suggests that contrast effects of speech rate are immune to selective attention, largely operating prior to attentional stream segregation in the auditory processing hierarchy.

Abstract

Speech sounds are perceived relative to spectral properties of surrounding speech. For instance, target words ambiguous between /bɪt/ (with low F1) and /bɛt/ (with high F1) are more likely to be perceived as “bet” after a ‘low F1’ sentence, but as “bit” after a ‘high F1’ sentence. However, it is unclear how these spectral contrast effects (SCEs) operate in multi-talker listening conditions. Recently, Feng and Oxenham [(2018b). J.Exp.Psychol.-Hum.Percept.Perform. 44(9), 1447–1457] reported that selective attention affected SCEs to a small degree, using two simultaneously presented sentences produced by a single talker. The present study assessed the role of selective attention in more naturalistic ‘cocktail party’ settings, with 200 lexically unique sentences, 20 target words, and different talkers. Results indicate that selective attention to one talker in one ear (while ignoring another talker in the other ear) modulates SCEs in such a way that only the spectral properties of the attended talker influences target perception. However, SCEs were much smaller in multi-talker settings (Experiment 2) than those in single-talker settings (Experiment 1). Therefore, the influence of SCEs on speech comprehension in more naturalistic settings (i.e., with competing talkers) may be smaller than estimated based on studies without competing talkers.

Abstract

How are space and time represented in the human mind? Here we evaluate two theoretical proposals, one suggesting a symmetric relationship between space and time (ATOM theory) and the other an asymmetric relationship (metaphor theory). In Experiment 1, Dutch-speakers saw 7-letter nouns that named concrete objects of various spatial lengths (tr. pencil, bench, footpath) and estimated how much time they remained on the screen. In Experiment 2, participants saw nouns naming temporal events of various durations (tr. blink, party, season) and estimated the words’ spatial length. Nouns that named short objects were judged to remain on the screen for a shorter time, and nouns that named longer objects to remain for a longer time. By contrast, variations in the duration of the event nouns’ referents had no effect on judgments of the words’ spatial length. This asymmetric pattern of cross-dimensional interference supports metaphor theory and challenges ATOM.

Abstract

Why do people accommodate to each other’s linguistic behavior? Studies of natural interactions (Giles, Taylor & Bourhis, 1973) suggest that speakers accommodate to achieve interactional goals, influencing what their interlocutor thinks or feels about them. But is this the only reason speakers accommodate? In real-world conversations, interactional motivations are ubiquitous, making it difficult to assess the extent to which they drive accommodation. Do speakers still accommodate even when interactional goals cannot be achieved, for instance, when their interlocutor cannot interpret their accommodation behavior? To find out, we asked participants to enter an immersive virtual reality (VR) environment and to converse with a virtual interlocutor. Participants accommodated to the speech rate of their virtual interlocutor even though he could not interpret their linguistic behavior, and thus accommodation could not possibly help them to achieve interactional goals. Results show that accommodation does not require explicit interactional goals, and suggest other social motivations for accommodation.

Abstract

Relational grammar was proposed in Suppes (1976) as a semantical grammar for natural language. Fragments considered so far are restricted to distributive notions. In this article, relational grammar is extended to collective notions.

Abstract

Data analysis workflows in many scientific domains have become increasingly complex and flexible. Here we assess the effect of this flexibility on the results of functional magnetic resonance imaging by asking 70 independent teams to analyse the same dataset, testing the same 9 ex-ante hypotheses1. The flexibility of analytical approaches is exemplified by the fact that no two teams chose identical workflows to analyse the data. This flexibility resulted in sizeable variation in the results of hypothesis tests, even for teams whose statistical maps were highly correlated at intermediate stages of the analysis pipeline. Variation in reported results was related to several aspects of analysis methodology. Notably, a meta-analytical approach that aggregated information across teams yielded a significant consensus in activated regions. Furthermore, prediction markets of researchers in the field revealed an overestimation of the likelihood of significant findings, even by researchers with direct knowledge of the dataset2,3,4,5. Our findings show that analytical flexibility can have substantial effects on scientific conclusions, and identify factors that may be related to variability in the analysis of functional magnetic resonance imaging. The results emphasize the importance of validating and sharing complex analysis workflows, and demonstrate the need for performing and reporting multiple analyses of the same data. Potential approaches that could be used to mitigate issues related to analytical variability are discussed.

Abstract

Musical score reading and word reading have much in common, from their historical origins to their cognitive foundations and neural correlates. In the ventral occipitotemporal cortex (VOT), the specialization of the so-called Visual Word Form Area for word reading has been linked to its privileged structural connectivity to distant language regions. Here we investigated how anatomical connectivity relates to the segregation of regions specialized for musical notation or words in the VOT. In a cohort of professional musicians and non-musicians, we used probabilistic tractography combined with task-related functional MRI to identify the connections of individually defined word- and music-selective left VOT regions. Despite their close proximity, these regions differed significantly in their structural connectivity, irrespective of musical expertise. The music-selective region was significantly more connected to posterior lateral temporal regions than the word-selective region, which, conversely, was significantly more connected to anterior ventral temporal cortex. Furthermore, musical expertise had a double impact on the connectivity of the music region. First, music tracts were significantly larger in musicians than in non-musicians, associated with marginally higher connectivity to perisylvian music-related areas. Second, the spatial similarity between music and word tracts was significantly increased in musicians, consistently with the increased overlap of language and music functional activations in musicians, as compared to non-musicians. These results support the view that, for music as for words, very specific anatomical connections influence the specialization of distinct VOT areas, and that reciprocally those connections are selectively enhanced by the expertise for word or music reading.

Abstract

(From the chapter) the first section considers very briefly the kinds of processes that can be inferred to underlie errors that do not set in until after a period of correct usage acquisition often seems to be a more extended process than we have envisioned summarize a currently influential model of how linguistic forms, meaning, and communication are interrelated in the acquisition of language, point out some challenging problems for this model, and suggest that the notion of "meaning" in language must be reconceptualized before we can hope to solve these problems evidence from several types of late errors is marshalled in support of these arguments (From the preface) provides many examples of new errors that children introduce at relatively advanced stages of mastery of semantics and syntax Bowerman views these seemingly backwards steps as indications of definite steps forward by the child achieving reflective, flexible and integrated systems of semantics and syntax (

Abstract

The theory that language acquisition is guided and constrained by inborn linguistic knowledge is assessed. Specifically, the "no negative evidence" view, the belief that linguistic theory should be restricted in such a way that the grammars it allows can be learned by children on the basis of positive evidence only, is explored. Child language data are cited in order to investigate influential innatist approaches to language acquisition. Baker's view that children are innately constrained in significant ways with respect to language acquisition is evaluated. Evidence indicates that children persistently make overgeneralizations of the sort that violate the constrained view of language acquisition. Since children eventually do develop correct adult grammar, they must have other mechanisms for cutting back on these overgeneralizations. Thus, any hypothesized constraints cannot be justified on grounds that without them the child would end up with overly general grammar. It is necessary to explicate the mechanisms by which children eliminate their tendency toward overgeneralization.

Abstract

This study reports three experiments on how children learning Mandarin Chinese comprehend and use aspect markers. These experiments examine the role of lexical aspect in children's acquisition of grammatical aspect. Results provide converging evidence for children's early sensitivity to (1) the association between atelic verbs and the imperfective aspect markers zai, -zhe, and -ne, and (2) the association between telic verbs and the perfective aspect marker -le. Children did not show a sensitivity in their use or understanding of aspect markers to the difference between stative and activity verbs or between semelfactive and activity verbs. These results are consistent with Slobin's (1985) basic child grammar hypothesis that the contrast between process and result is important in children's early acquisition of temporal morphology. In contrast, they are inconsistent with Bickerton's (1981, 1984) language bioprogram hypothesis that the distinctions between state and process and between punctual and nonpunctual are preprogrammed into language learners. We suggest new ways of looking at the results in the light of recent probabilistic hypotheses that emphasize the role of input, prototypes and connectionist representations.

Abstract

To clarify whether the neural pathways concerning color processing are the same for natural objects, for artifacts objects and for non-sense objects we examined functional magnetic resonance imaging (FMRI) responses during a covert naming task including the factors color (color vs. black&white (B&W)) and stimulus type (natural vs. artifacts vs. non-sense objects). Our results indicate that the superior parietal lobule and precuneus (BA 7) bilaterally, the right hippocampus and the right fusifom gyrus (V4) make part of a network responsible for color processing both for natural and artifacts objects, but not for non-sense objects. The recognition of non-sense colored objects compared to the recognition of color objects activated the posterior cingulate/precuneus (BA 7/23/31), suggesting that color attribute induces the mental operation of trying to associate a non-sense composition with a familiar objects. When color objects (both natural and artifacts) were contrasted with color nonobjects we observed activations in the right parahippocampal gyrus (BA 35/36), the superior parietal lobule (BA 7) bilaterally, the left inferior middle temporal region (BA 20/21) and the inferior and superior frontal regions (BA 10/11/47). These additional activations suggest that colored objects recruit brain regions that are related to visual semantic information/retrieval and brain regions related to visuo-spatial processing. Overall, the results suggest that color information is an attribute that improve object recognition (based on behavioral results) and activate a specific neural network related to visual semantic information that is more extensive than for B&W objects during object recognition

Abstract

In order to clarify whether the influence of color knowledge information in object recognition depends on the presence of the appropriate surface color, we designed a name—object verification task. The relationship between color and shape information provided by the name and by the object photo was manipulated in order to assess color interference independently of shape interference. We tested three different versions for each object: typically colored, black and white, and nontypically colored. The response times on the nonmatching trials were used to measure the interference between the name and the photo. We predicted that the more similar the name and the photo are, the longer it would take to respond. Overall, the color similarity effect disappeared in the black-and-white and nontypical color conditions, suggesting that the influence of color knowledge on object recognition depends on the presence of the appropriate surface color information.

Abstract

The adverb now in English (nu in Dutch) can draw listeners’ attention to an upcoming contrast (e.g., ‘Put X in Y. Now put X in Z’). In Dutch, but not English, the position of this sequential adverb may disambiguate which constituent is contrasted. We investigated whether and how the intonational realization of now/nu is varied to signal different scopes and whether it interacts with word order. Three contrast conditions (contrast in object, location, or both) were produced by eight Dutch and eight English speakers. Results showed no consistent use of word order for scope disambiguation in Dutch. Importantly, independent of language, an unaccented now/nu signaled a contrasting object while an accented now/nu signaled a contrast in the location. Since these intonational patterns were independent of word order, we interpreted the results in the framework of grammatical saliency: now/nu appears to be unmarked when the contrast lies in a salient constituent (the object) but marked with a prominent rise when a less salient constituent is contrasted (the location).

Abstract

Sentences with a contrastive intonation contour are usually produced when the speaker entertains alternatives to the accented words. However, such contrastive sentences are frequently produced without making the alternatives explicit for the listener. In two cross-modal associative priming experiments we tested in Dutch whether such contextual alternatives become available to listeners upon hearing a sentence with a contrastive intonation contour compared with a sentence with a non-contrastive one. The first experiment tested the recognition of contrastive associates (contextual alternatives to the sentence-final primes), the second one the recognition of non-contrastive associates (generic associates which are not alternatives). Results showed that contrastive associates were facilitated when the primes occurred in sentences with a contrastive intonation contour but not in sentences with a non-contrastive intonation. Non-contrastive associates were weakly facilitated independent of intonation. Possibly, contrastive contours trigger an accommodation mechanism by which listeners retrieve the contrast available for the speaker.

Abstract

Sentences with a contrastive intonation contour are usually produced when the speaker entertains alternatives to the accented words. However, such contrastive sentences are frequently produced without making the alternatives explicit for the listener. In two cross-modal associative priming experiments we tested in Dutch whether such contextual alternatives become available to listeners upon hearing a sentence with a contrastive intonation contour compared with a sentence with a non-contrastive one. The first experiment tested the recognition of contrastive associates (contextual alternatives to the sentence-final primes), the second one the recognition of non-contrastive associates (generic associates which are not alternatives). Results showed that contrastive associates were facilitated when the primes occurred in sentences with a contrastive intonation contour but not in sentences with a non-contrastive intonation. Non-contrastive associates were weakly facilitated independent of intonation. Possibly, contrastive contours trigger an accommodation mechanism by which listeners retrieve the contrast available for the speaker.

Abstract

Interference in picture naming occurs from representing a partner's preparations to speak (Gambi, van de Cavey, & Pickering, 2015). We tested the origins of this interference using a simple non-communicative joint naming task based on Gambi et al. (2015), where response latencies indexed interference from partner task and partner speech content, and eye fixations to partner objects indexed overt attention. Experiment 1 contrasted a partner-present condition with a control partner-absent condition to establish the role of the partner in eliciting interference. For latencies, we observed interference from the partner's task and speech content, with interference increasing due to partner task in the partner-present condition. Eye-tracking measures showed that interference in naming was not due to overt attention to partner stimuli but to broad expectations about likely utterances. Experiment 2 examined whether an equivalent non-verbal task also elicited interference, as predicted from a language as joint action framework. We replicated the finding of interference due to partner task and again found no relationship between overt attention and interference. These results support Gambi et al. (2015). Individuals co-represent a partner's task while speaking, and doing so does not require overt attention to partner stimuli.

Abstract

Existing work shows that readers often interpret grammatical errors (e.g., The key to the cabinets *were shiny) and sentence-level blends (“without-blend”: Claudia left without her headphones *off) in a non-literal fashion, inferring that a more frequent or more canonical utterance was intended instead. This work examines how interlocutor identity affects the processing and interpretation of anomalous sentences. We presented anomalies in the context of “emails” attributed to various writers in a self-paced reading paradigm and used comprehension questions to probe how sentence interpretation changed based upon properties of the item and properties of the “speaker.” Experiment 1 compared standardised American English speakers to L2 English speakers; Experiment 2 compared the same standardised English speakers to speakers of a non-Standardised American English dialect. Agreement errors and without-blends both led to more non-literal responses than comparable canonical items. For agreement errors, more non-literal interpretations also occurred when sentences were attributed to speakers of Standardised American English than either non-Standardised group. These data suggest that understanding sentences relies on expectations and heuristics about which utterances are likely. These are based upon experience with language, with speaker-specific differences, and upon more general cognitive biases.

Abstract

Agreement attraction in comprehension (when an ungrammatical verb is read quickly if preceded by a feature-matching local noun) is well described by a cue-based retrieval framework. This suggests a role for lexical retrieval in attraction. To examine this, we manipulated two probabilistic factors known to affect lexical retrieval: local noun word frequency and morpho-orthography (agreement morphology realised with or without –s endings) in a self-paced reading study. Noun number and word frequency affected noun and verb region reading times, with higher-frequency words not eliciting attraction. Morpho-orthography impacted verb processing but not attraction: atypical plurals led to slower verb reading times regardless of verb number. Exploratory individual difference analyses further underscore the importance of lexical retrieval dynamics in sentence processing. This provides evidence that agreement operates via a cue-based retrieval mechanism over lexical representations that vary in their strength and association to number features.

Abstract

Computation in neuronal assemblies is putatively reflected in the excitatory and inhibitory cycles of activation distributed throughout the brain. In speech and language processing, coordination of these cycles resulting in phase synchronization has been argued to reflect the integration of information on different timescales (e.g. segmenting acoustics signals to phonemic and syllabic representations; (Giraud and Poeppel 2012 Nat. Neurosci.15, 511 (doi:10.1038/nn.3063)). A natural extension of this claim is that phase synchronization functions similarly to support the inference of more abstract higher-level linguistic structures (Martin 2016 Front. Psychol.7, 120; Martin and Doumas 2017 PLoS Biol. 15, e2000663 (doi:10.1371/journal.pbio.2000663); Martin and Doumas. 2019 Curr. Opin. Behav. Sci.29, 77–83 (doi:10.1016/j.cobeha.2019.04.008)). Hale et al. (Hale et al. 2018 Finding syntax in human encephalography with beam search. arXiv 1806.04127 (http://arxiv.org/abs/1806.04127)) showed that syntactically driven parsing decisions predict electroencephalography (EEG) responses in the time domain; here we ask whether phase synchronization in the form of either inter-trial phrase coherence or cross-frequency coupling (CFC) between high-frequency (i.e. gamma) bursts and lower-frequency carrier signals (i.e. delta, theta), changes as the linguistic structures of compositional meaning (viz., bracket completions, as denoted by the onset of words that complete phrases) accrue. We use a naturalistic story-listening EEG dataset from Hale et al. to assess the relationship between linguistic structure and phase alignment. We observe increased phase synchronization as a function of phrase counts in the delta, theta, and gamma bands, especially for function words. A more complex pattern emerged for CFC as phrase count changed, possibly related to the lack of a one-to-one mapping between ‘size’ of linguistic structure and frequency band—an assumption that is tacit in recent frameworks. These results emphasize the important role that phase synchronization, desynchronization, and thus, inhibition, play in the construction of compositional meaning by distributed neural networks in the brain.

Abstract

We describe our computer-supported framework to overcome the rule of metadata schism. It combines the use of controlled vocabularies, managed by a data category registry, with a component-based approach, where the categories can be combined to yield complex metadata structures. A metadata scheme devised in this way will thus be grounded in its use of categories. Schema designers will profit from existing prefabricated larger building blocks, motivating re-use at a larger scale. The common base of any two metadata schemes within this framework will solve, at least to a good extent, the semantic interoperability problem, and consequently, further promote systematic use of metadata for existing resources and tools to be shared.

Abstract

Unlike most of the world's languages, Korean distinguishes three types of voiceless stops, namely lenis, fortis, and aspirated stops. All occur at three places of articulation. In previous work, acoustic measurements are mostly collapsed over the three places of articulation. This study therefore provides acoustic measurements of Korean lenis, fortis, and aspirated stops at all three places of articulation separately. Clear differences are found among the acoustic characteristics of the stops at the different places of articulation

Abstract

This paper shows that the effect of different types of noise on recognition of different phonemes by native versus non-native listeners is highly variable, even within classes of phonemes with the same manner or place of articulation. In a phoneme identification experiment, English and Dutch listeners heard all 24 English consonants in VCV stimuli in quiet and in three types of noise: competing talker, speech-shaped noise, and modulated speech-shaped noise (all with SNRs of −6 dB). Differential effects of noise type for English and Dutch listeners were found for eight consonants (/p t k g m n ŋ r/) but not for the other 16 consonants. For those eight consonants, effects were again highly variable: each noise type hindered non-native listeners more than native listeners for some of the target sounds, but none of the noise types did so for all of the target sounds, not even for phonemes with the same manner or place of articulation. The results imply that the noise types employed will strongly affect the outcomes of any study of native and non-native speech perception in noise.

Abstract

This study investigates the psycholinguistic process underlying triggered codeswitching – codeswitching facilitated by the occurrence of cognates – within the context of conversational dynamics. It confirms that, in natural bilingual speech, lexical selection of cognates can facilitate codeswitching by enhancing the activation of the non-selected language. Analyses of a large-scale corpus of Welsh–English conversational speech showed that 1) producing cognates facilitated codeswitching, 2) speakers who generally produced more cognates generally codeswitched more, even in clauses that did not contain cognates, 3) larger numbers of cognates in a clause increased the likelihood of codeswitching, 4) codeswitching temporarily remained facilitated after the production of cognates, and 5) hearing rather than producing cognates did not facilitate codeswitching. The findings confirm the validity of the proposed cognitive account of triggered codeswitching, and clarify the relation between the lexical activation of cognates and consecutive language choice, in accord with current insights in lexical processing.

Abstract

We investigated the extent to which emotionally valenced words automatically cue spatio-motor representations. Participants made speeded button presses, moving their hand upward or downward while viewing words with positive or negative valence. Only the color of the words was relevant to the response; on target trials, there was no requirement to read the words or process their meaning. In Experiment 1, upward responses were faster for positive words, and downward for negative words. This effect was extinguished, however, when words were repeated. In Experiment 2, participants performed the same primary task with the addition of distractor trials. Distractors either oriented attention toward the words’ meaning or toward their color. Congruity effects were increased with orientation to meaning, but eliminated with orientation to color. When people read words with emotional valence, vertical spatio-motor representations are activated highly automatically, but this automaticity is modulated by repetition and by attentional orientation to the words’ form or meaning.

Abstract

This study examined whether listeners align to reduced speech. Participants were asked to shadow sentences from a casual speech corpus containing canonical and reduced targets. Participants' productions showed alignment: durations of canonical targets were longer than durations of reduced targets; and participants often imitated the segment types (canonical versus reduced) in both targets. The effect sizes were similar to previous work on alignment. In addition, shadowed productions were overall longer in duration than the original stimuli and this effect was larger for reduced than canonical targets. A possible explanation for this finding is that listeners reconstruct canonical forms from reduced forms.

Abstract

This paper investigates whether surprisal theory can account for differential processing difficulty in the NP-/S-coordination ambiguity in Dutch. Surprisal is estimated using a Probabilistic Context-Free Grammar (PCFG), which is induced from an automatically annotated corpus. We find that our lexicalized surprisal model can account for the reading time data from a classic experiment on this ambiguity by Frazier (1987). We argue that syntactic and lexical probabilities, as specified in a PCFG, are sufficient to account for what is commonly referred to as an NP-coordination preference.

Abstract

Languages vary typologically in their lexicalization of Path of motion (Talmy 1991). Furthermore, lexicalization patterns are argued to affect syntactic packaging at the level of the clause (e.g. Slobin 1996b) and tend to transfer from a first (L1) to a second language (L2) in second language acquisition (e.g. Cadierno 2004). From this crosslinguistic and developmental evidence, typological preferences for Path expression appear highly robust features of a first language. The current study examines the extent to which preferences for Path encoding really are as enduring as they seem by investigating (1) whether Japanese follows patterns identified for other verb-framed languages like Spanish, and (2) whether patterns established in one’s first language can change after acquisition of a second language. L1 performance of native speakers of Japanese with intermediate-level knowledge of English was compared to that of monolingual speakers of Japanese and English. Results showed that monolingual Japanese speakers followed basic lexicalization patterns typical of other verb-framed languages, but with different realizations of Path packaging within the clause. Moreover, non-monolingual Japanese speakers displayed both English- and Japanese-like patterns for lexicalization with significantly more Path information per clause than either group of monolinguals. Implications for typology and second language acquisition are discussed.

Abstract

A major finding in studies of early vocabulary acquisition has been that children tend to learn a lot of nouns early but make do with relatively few verbs, among which semantically general-purpose verbs like do, make, get, have, give, come, go, and be play a prominent role. The preponderance of nouns is explained in terms of nouns labelling concrete objects beings “easier” to learn than verbs, which label relational categories. Nouns label “natural categories” observable in the world, verbs label more linguistically and culturally specific categories of events linking objects belonging to such natural categories (Gentner 1978, 1982; Clark 1993). This view has been challenged recently by data from children learning certain non-Indo-European languges like Korean, where children have an early verb explosion and verbs dominate in early child utterances. Children learning the Mayan language Tzeltal also acquire verbs early, prior to any noun explosion as measured by production. Verb types are roughly equivalent to noun types in children’s beginning production vocabulary and soon outnumber them. At the one-word stage children’s verbs mostly have the form of a root stripped of affixes, correctly segmented despite structural difficulties. Quite early (before the MLU 2.0 point) there is evidence of productivity of some grammatical markers (although they are not always present): the person-marking affixes cross-referencing core arguments, and the completive/incompletive aspectual distinctions. The Tzeltal facts argue against a natural-categories explanation for childre’s early vocabulary, in favor of a view emphasizing the early effects of language-specific properties of the input. They suggest that when and how a child acquires a “verb” category is centrally influenced by the structural properties of the input, and that the semantic structure of the language - where the referential load is concentrated - plays a fundamental role in addition to distributional facts.

Abstract

When Tzeltal children in the Mayan community of Tenejapa, in southern Mexico, begin speaking, their production vocabulary consists predominantly of verb roots, in contrast to the dominance of nouns in the initial vocabulary of first‐language learners of Indo‐European languages. This article proposes that a particular Tzeltal conversational feature—known in the Mayanist literature as "dialogic repetition"—provides a context that facilitates the early analysis and use of verbs. Although Tzeltal babies are not treated by adults as genuine interlocutors worthy of sustained interaction, dialogic repetition in the speech the children are exposed to may have an important role in revealing to them the structural properties of the language, as well as in socializing the collaborative style of verbal interaction adults favor in this community.

Abstract

The surge of research activity focussing on children's acquisition of verbs (e.g., Tomasello and Merriman 1996) addresses some fundamental questions: Just how variable across languages, and across individual children, is the process of verb learning? How specific are arguments to particular verbs in early child language? How does the grammatical category 'Verb' develop? The position of Universal Grammar, that a verb category is early, contrasts with that of Tomasello (1992), Pine and Lieven and their colleagues (1996, in press), and many others, that children develop a verb category slowly, gradually building up subcategorizations of verbs around pragmatic, syntactic, and semantic properties of the language they are exposed to. On this latter view, one would expect the language which the child is learning, the cultural milieu and the nature of the interactions in which the child is engaged, to influence the process of acquiring verb argument structures. This paper explores these issues by examining the development of argument representation in the Mayan language Tzeltal, in both its lexical and verbal cross-referencing forms, and analyzing the semantic and pragmatic factors influencing the form argument representation takes. Certain facts about Tzeltal (the ergative/ absolutive marking, the semantic specificity of transitive and positional verbs) are proposed to affect the representation of arguments. The first 500 multimorpheme combinations of 3 children (aged between 1;8 and 2;4) are examined. It is argued that there is no evidence of semantically light 'pathbreaking' verbs (Ninio 1996) leading the way into word combinations. There is early productivity of cross-referencing affixes marking A, S, and O arguments (although there are systematic omissions). The paper assesses the respective contributions of three kinds of factors to these results - structural (regular morphology), semantic (verb specificity) and pragmatic (the nature of Tzeltal conversational interaction).

Abstract

In this paper presents evidence of the disputed existence of an electrophysiological marker for the lexical-categorical distinction between open- and closed-class words. Event-related brain potentials were recorded from the scalp while subjects read a story. Separate waveforms were computed for open- and closed-class words. Two aspects of the waveforms could be reliably related to vocabulary class. The first was an early negativity in the 230- to 350-msec epoch, with a bilateral anterior predominance. This negativity was elicited by open- and closed-class words alike, was not affected by word frequency or word length, and had an earlier peak latency for closed-class words. The second was a frontal slow negative shift in the 350- to 500-msec epoch, largest over the left side of the scalp. This late negativity was only elicited by closed-class words. Although the early negativity cannot serve as a qualitative marker of the open- and closed-class distinction, it does reflect the earliest electrophysiological manifestation of the availability of categorical information from the mental lexicon. These results suggest that the brain honors the distinction between open- and closed-class words, in relation to the different roles that they play in on-line sentence processing.

Abstract

A study is presented on the effects of discourse–semantic and lexical–syntactic information during spoken sentence processing. Event-related brain potentials (ERPs) were registered while subjects listened to discourses that ended in a sentence with a temporary syntactic ambiguity. The prior discourse–semantic information biased toward one analysis of the temporary ambiguity, whereas the lexical-syntactic information allowed only for the alternative analysis. The ERP results show that discourse–semantic information can momentarily take precedence over syntactic information, even if this violates grammatical gender agreement rules.

Abstract

This is an encyclopedia entry surveying anthropological approaches to cognition and culture.

Abstract

Two experiments are reported that provide evidence on task-induced effects during
visual lexical processing in a primetarget semantic priming paradigm. The research focuses on target expectancy effects by manipulating the proportion of semantically related and unrelated word pairs. In Experiment 1, a lexical decision task was used and reaction times (RTs) and event-related brain potentials (ERPs) were obtained. In Experiment 2, subjects silently read the stimuli, without any additional task demands, and ERPs were recorded. The RT and ERP results of Experiment 1 demonstrate that an expectancy mechanism contributed to the priming effect when a high proportion of related word pairs was presented. The ERP results of Experiment 2 show that in the absence of extraneous task requirements, an expectancy mechanism is not active. However, a standard ERP semantic priming effect was obtained in Experiment 2. The combined results show that priming effects due to relatedness proportion are induced by task demands and are not a standard aspect of online lexical processing.

Abstract

In reaction to the dominance of universalism in the 1970s and '80s, there have recently been a number of reappraisals of the relation between language and cognition, and the field of cognitive anthropology is flourishing in several new directions in both America and Europe. This is partly due to a renewal and re-evaluation of approaches to the question of linguistic relativity associated with Whorf, and partly to the inspiration of modern developments in cognitive science. This review briefly sketches the history of cognitive anthropology and surveys current research on both sides of the Atlantic. The focus is on assessing current directions, considering in particular, by way of illustration, recent work in cultural models and on spatial language and cognition. The review concludes with an assessment of how cognitive anthropology could contribute directly both to the broader project of cognitive science and to the anthropological study of how cultural ideas and practices relate to structures and processes of human cognition.

Abstract

How are events framed in narrative? Speakers of English (a 'satellite-framed' language), when 'reading' Mercer Mayer's wordless picture book 'Frog, Where Are You?', find the story self-evident: a boy has a dog and a pet frog; the frog escapes and runs away; the boy and dog look for it across hill and dale, through woods and over a cliff, until they find it and return home with a baby frog child of the original pet frog. In Tzeltal, as spoken in a Mayan community in southern Mexico, the story is somewhat different, because the language structures event descriptions differently. Tzeltal is in part a 'verb-framed' language with a set of Path-encoding motion verbs, so that the bare bones of the Frog story can consist of verbs translating as 'go'/'pass by'/'ascend'/ 'descend'/ 'arrive'/'return'. But Tzeltal also has satellite-framing adverbials, grammaticized from the same set of motion verbs, which encode the direction of motion or the orientation of static arrays. Furthermore, vivid pictorial detail is provided by positional verbs which can describe the position of the Figure as an outcome of a motion event; motion and stasis are thereby combined in a single event description. (For example:  jipot jawal "he has been thrown (by the deer) lying­_face_upwards_spread-eagled". This paper compares the use of these three linguistic resources in Frog Story narratives from  Tzeltal adults and children, looks at their development in the narratives of children, and considers the results in relation to those from Berman and Slobin's (1996) comparative study of adult and child Frog stories.

Abstract

In the face of the prevailing assumption among cognitive scientists that human spatial cognition is essentially egocentric, with objects located in reference to the orientation of ego's own body (hence left/right, up/down, and front/back oppositions), the Mayan language Tzeltal provides a telling counterexample. This article examines a set of conceptual oppositions in Tzeltal, uphill/downhill/across, that provides an absolute system of coordinates with respect to which the location of objects and their trajectories on both micro and macro scales are routinely described.

Abstract

This is a reprint of Brown 1990.

Abstract

This is a Spanish translation of Brown 1997.

Abstract

This paper reports the results of a study of Tzeltal questions and their responses, based on a collection of 419 question/response sequences drawn from video recordings of ‘maximally casual’ naturally occurring face-to-face interactions in a Tzeltal (Mayan) community. I describe the lexical and grammatical resources for formulating content and polar questions in Tzeltal, the different kinds of social actions that questions can be used to perform and their relative frequency in the data, and the characteristic properties of responses to questions. This is part of a large-scale comparative study of questions in 10 different languages, and we find that Tzeltal is like most others in making much more use of polar than of content questions, and in the strong tendency for confirming answers to polar questions. Tzeltal is however unusual in three respects: in the comparatively minimal use of gaze to select next speaker, in the frequency with which answers take the form of repeats, and in the complete absence of visible-only responses (e.g., nods or head-shakes). There are also some language-specific properties of question–answer sequences that reveal cultural shaping of sequencing in conversation.

Abstract

This is an encyclopedia entry describing conversational and interactional uses of linguistic repetition.

Abstract

This article is a reprint of chapter 1, the introduction to Brown and Levinson, 1987, Politeness: Some universals in language usage (Cambridge University Press).

Abstract

This article is a reprint of chapter 1, the introduction to Brown and Levinson, 1987, Politeness: Some universals in language usage (Cambridge University Press).

Abstract

The N400 is an endogenous event-related brain potential (ERP) that is sensitive to semantic processes during language comprehension. The general question we address in this paper is which aspects of the comprehension process are manifest in the N400. The focus is on the sensitivity of the N400 to the automatic process of lexical access, or to the controlled process of lexical integration. The former process is the reflex-like and effortless behavior of computing a form representation of the linguistic signal, and of mapping this representation onto corresponding entries in the mental lexicon. The latter process concerns the integration of a spoken or written word into a higher-order meaning representation of the context within which it occurs. ERPs and reaction times (RTs) were acquired to target words preceded by semantically related and unrelated prime words. The semantic relationship between a prime and its target has been shown to modulate the amplitude of the N400 to the target. This modulation can arise from lexical access processes, reflecting the automatic spread of activation between words related in meaning in the mental lexicon. Alternatively, the N400 effect can arise from lexical integration processes, reflecting the relative ease of meaning integration between the prime and the target. To assess the impact of automatic lexical access processes on the N400, we compared the effect of masked and unmasked presentations of a prime on the N400 to a following target. Masking prevents perceptual identification, and as such it is claimed to rule out effects from controlled processes. It therefore enables a stringent test of the possible impact of automatic lexical access processes on the N400. The RT study showed a significant semantic priming effect under both unmasked and masked presentations of the prime. The result for masked priming reflects the effect of automatic spreading of activation during the lexical access process. The ERP study showed a significant N400 effect for the unmasked presentation condition, but no such effect for the masked presentation condition. This indicates that the N400 is not a manifestation of lexical access processes, but reflects aspects of semantic integration processes.

Abstract

In a critique of the current state of theories of language acquisition, Bowerman (1985) has argued forcibly for the need to take crosslinguistic variation in semantic structure seriously, in order to understand children's acquisition of semantic categories in the process of learning their language. The semantics of locative expressions in the Mayan language Tzeltal exemplifies this point, for no existing theory of spatial expressions provides an adequate basis for capturing the semantic structure of spatial description in this Mayan language. In this paper I describe some of the characteristics of Tzeltal locative descriptions, as a contribution to the growing body of data on crosslinguistic variation in this domain and as a prod to ideas about acquisition processes, confining myself to the topological notions of 'on' and 'in', and asking whether, and how, these notions are involved in the semantic distinctions underlying Tzeltal locatives.

Abstract

This is a Spanish translation of Brown 2002, 'Everyone has to lie in Tzeltal'. Translated by B. E. Alvaraz Klein

Abstract

Background Retracing the genetic histories of the descendant populations of the Slave Trade (16th-19th centuries) is particularly challenging due to the diversity of African ethnic groups involved and the different hybridisation processes with Europeans and Amerindians, which have blurred their original genetic inheritances. The Noir Marron in French Guiana are the direct descendants of maroons who escaped from Dutch plantations in the current day Surinam. They represent an original ethnic group with a highly blended culture. Uniparental markers (mtDNA and NRY) coupled with HTLV-1 sequences (env and LTR) were studied to establish the genetic relationships linking them to African American and African populations. Results All genetic systems presented a high conservation of the African gene pool (African ancestry: mtDNA = 99.3%; NRY = 97.6%; HTLV-1 env = 20/23; HTLV-1 LTR = 6/8). Neither founder effect nor genetic drift was detected and the genetic diversity is within a range commonly observed in Africa. Higher genetic similarities were observed with the populations inhabiting the Bight of Benin (from Ivory Coast to Benin). Other ancestries were identified but they presented an interesting sex-bias. Whilst male origins spread throughout the north of the bight (from Benin to Senegal), female origins were spread throughout the south (from the Ivory Coast to Angola). Conclusions The Noir Marron are unique in having conserved their African genetic ancestry, despite major cultural exchanges with Amerindians and Europeans through inhabiting the same region for four centuries. Their maroon identity and the important number of slaves deported in this region have maintained the original African diversity. All these characteristics permit to identify a major origin located in the former region of the Gold Coast and the Bight of Benin; regions highly impacted by slavery, from which goes a sex-biased longitudinal gradient of ancestry.

Abstract

Speech input causes listeners to activate multiple
candidate words which then compete with one
another. These include onset competitors, that share a
beginning (bumper, butter), but also, counterintuitively,
rhyme competitors, sharing an ending
(bumper, jumper). In L1, competition is typically
stronger for onset than for rhyme. In L2, onset
competition has been attested but rhyme competition
has heretofore remained largely unexamined. We
assessed L1 (Dutch) and L2 (English) word
recognition by the same late-bilingual individuals. In
each language, eye gaze was recorded as listeners
heard sentences and viewed sets of drawings: three
unrelated, one depicting an onset or rhyme competitor
of a word in the input. Activation patterns revealed
substantial onset competition but no significant
rhyme competition in either L1 or L2. Rhyme
competition may thus be a “luxury” feature of
maximally efficient listening, to be abandoned when
resources are scarcer, as in listening by late
bilinguals, in either language.

Abstract

As a rule, listening is easier in first (L1) than second languages (L2); difficult L2 listening can challenge even highly proficient users. We here examine one particular listening function, adaptation to novel talkers, in such a high-proficiency population: Dutch emigrants to Australia, predominantly using English outside the family, but all also retaining L1 proficiency. Using lexically-guided perceptual learning (Norris, McQueen & Cutler, 2003), we investigated these listeners’ adaptation to an ambiguous speech sound, in parallel experiments in both their L1 and their L2. A control study established that perceptual learning outcomes were unaffected by the procedural measures required for this double comparison. The emigrants showed equivalent proficiency in tests in both languages, robust perceptual adaptation in their L2, English, but no adaptation in L1. We propose that adaptation to novel talkers is a language-specific skill requiring regular novel practice; a limited set of known (family) interlocutors cannot meet this requirement.

Abstract

Book reading shows large individual variability and correlates with better language ability and more empathy. This makes reading exposure an interesting variable to study. Research in English suggests that an author recognition test is the most reliable objective assessment of reading frequency. In this article, we describe the efforts we made to build and test a Dutch author recognition test (DART for older participants and DART_R for younger participants). Our data show that the test is reliable and valid, both in the Netherlands and in Belgium (split-half reliability over .9 with university students, significant correlations with language abilities) and can be used with a young, non-university population. The test is free to use for research purposes.

Abstract

Acquisition and processing of written and spoken language is an impressive cognitive accomplishment considering the complexity of the tasks. While only humans seem to have evolved to the fullest extent the capacity that underpins these remarkable feats of development and civilization, the exact nature of such capacity has been subject to ongoing research. In this chapter, we focus on language competence and what makes it unique among the communication systems of different species. We then elaborate on the classical debate between nativist and environmentalist accounts of language acquisition, with reference to evidence for and against the critical period hypothesis. After introducing the regularity embedded in different languages and particularly in drastically different orthographies, we present behavioral and neurophysiological evidence for the sensitivity to systematic mapping between orthography and phonology. Because learning to read is to master such mapping, we assume that the ability to use statistical learning to appreciate the dependency among items would contribute to literacy acquisition. Empirical results from behavioral and neuroimaging experiments conducted in our and other laboratories provide support for the close link between statistical learning and literacy acquisition in native and foreign language. Such findings highlight the significance of domain-general statistical learning to domain-specific language acquisition, and point to an important direction for theories and practices of language education.

Abstract

The recently disclosed plasticity properties of adult-derived stem cells, their ability to be reprogrammed by defined factors into pluripotent stem cells and the comprehension of “epi”-genetic mechanisms underlying stem cells differentiation process has opened unexpected avenues to attempt regeneration of tissues affected by degenerative disorders and prompted the birth of the new “regenerative medicine” concept. Regeneration of the vascular and myocardial tissues is considered a primary endpoint to limit the consequences of acute and chronic ischemic heart disorders. Cellular therapy of the ischemic heart has been attempted in more than 1000 patients worldwide and the results of the first meta-analysis studies have been recently made available. In several cases, the results did not fulfill the expectations. In fact, they unpredictably indicated modest, yet significant, clinical benefits in patients compared to the outstanding results using stem cells in animal models of ischemic heart and peripheral disease. Several interpretations have been raised to explain these discrepancies. These include lifestyle and risk factor-associated modifications of the stem cell biological activity, but also procedural problems in the translation of cells from bench to bedside. The present review will cover light and shaded areas in the cardiovascular cellular therapy field, and will discuss about recent advances and related patents designed to enhance efficiency of stem cell therapy in patients with cardiovascular disease. These advancements will be discussed in the light of the most advanced issues that have been introduced worldwide by Regulatory Agencies. - See more at: http://www.eurekaselect.com/85525/article#sthash.lEuaE1A5.dpuf

Abstract

In individuals with synaesthesia specific sensory stimulation leads to unusual concurrent perceptions in the same or a different modality. Recent studies have demonstrated a high co-occurrence between synaesthesia and autism spectrum disorder (ASD), a condition also characterized by altered perception. A potentially shared characteristic of synaesthesia and ASD is a bias towards local (detail-focussed) perception. We investigated whether a bias towards local perception is indeed shared between synaesthesia and ASD. In a neurotypical population, we studied the relation between the degree of autistic traits (measured by the AQ) and the degree of grapheme-colour synaesthesia (measured by a consistency task), as well as whether both are related to a local bias in tasks assessing local/global visual perception. A positive correlation between total AQ scores and the degree of synaesthesia was found. Our study extends previous studies that found a high ASD-synaesthesia co-occurrence in clinical populations. Consistent with the hypothesized local perceptual bias in ASD, scores on the AQ-attention to detail subscale were related to increased performance on an Embedded Figures Task (EFT), and we found evidence for a relation to reduced susceptibility to visual illusions. We found no relation between autistic traits and local visual perception in a motion coherence task (MCT). Also, no relation between synaesthesia and local visual perception was found, although a reduced susceptibility to visual illusions resembled the results obtained for AQ-atttention to detail subscale. A suggested explanation for the absence of a relationship between the degree of synaesthesia and a local bias is that a possible local bias might be more pronounced in supra-threshold synaesthetes (compared to neurotypicals).

Abstract

This study examines whether the production of words with two phonological variants involves single or multiple lexical phonological representations. Three production experiments investigated the roles of the relative frequencies of the two pronunciation variants of French words with schwa: the schwa variant (e.g., Image ) and the reduced variant (e.g., Image ). In two naming tasks and in a symbol–word association learning task, variants with higher relative frequencies were produced faster. This suggests that the production lexicon keeps a frequency count for each variant and hence that schwa words are represented in the production lexicon with two different lexemes. In addition, the advantage for schwa variants over reduced variants in the naming tasks but not in the learning task and the absence of a variant relative frequency effect for schwa variants produced in isolation support the hypothesis that context affects the variants’ lexical activation and modulates the effect of variant relative frequency.

Abstract

The human brain can process facial expressions of emotions rapidly and without awareness. Several studies in patients with damage to their primary visual cortices have shown that they may be able to guess the emotional expression on a face despite their cortical blindness. This non-conscious processing, called affective blindsight, may arise through an intact subcortical visual route that leads from the superior colliculus to the pulvinar, and thence to the amygdala. This pathway is thought to process the crude visual information conveyed by the low spatial frequencies of the stimuli.

In order to investigate whether this is the case, we studied a patient (TN) with bilateral cortical blindness and affective blindsight. An fMRI paradigm was performed in which fearful and neutral expressions were presented using faces that were either unfiltered, or filtered to remove high or low spatial frequencies. Unfiltered fearful faces produced right amygdala activation although the patient was unaware of the presence of the stimuli. More importantly, the low spatial frequency components of fearful faces continued to produce right amygdala activity while the high spatial frequency components did not. Our findings thus confirm that the visual information present in the low spatial frequencies is sufficient to produce affective blindsight, further suggesting that its existence could rely on the subcortical colliculo-pulvino-amygdalar pathway.