Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context
Healthy Brain Study Consortium, Aarts, E., Akkerman, A., Altgassen, M., Bartels, R., Beckers, D., Bevelander, K., Bijleveld, E., Blaney Davidson, E., Boleij, A., Bralten, J., Cillessen, T., Claassen, J., Cools, R., Cornelissen, I., Dresler, M., Eijsvogels, T., Faber, M., Fernández, G., Figner, B., Fritsche, M. and 67 moreHealthy Brain Study Consortium, Aarts, E., Akkerman, A., Altgassen, M., Bartels, R., Beckers, D., Bevelander, K., Bijleveld, E., Blaney Davidson, E., Boleij, A., Bralten, J., Cillessen, T., Claassen, J., Cools, R., Cornelissen, I., Dresler, M., Eijsvogels, T., Faber, M., Fernández, G., Figner, B., Fritsche, M., Füllbrunn, S., Gayet, S., Van Gelder, M. M. H. J., Van Gerven, M., Geurts, S., Greven, C. U., Groefsema, M., Haak, K., Hagoort, P., Hartman, Y., Van der Heijden, B., Hermans, E., Heuvelmans, V., Hintz, F., Den Hollander, J., Hulsman, A. M., Idesis, S., Jaeger, M., Janse, E., Janzing, J., Kessels, R. P. C., Karremans, J. C., De Kleijn, W., Klein, M., Klumpers, F., Kohn, N., Korzilius, H., Krahmer, B., De Lange, F., Van Leeuwen, J., Liu, H., Luijten, M., Manders, P., Manevska, K., Marques, J. P., Matthews, J., McQueen, J. M., Medendorp, P., Melis, R., Meyer, A. S., Oosterman, J., Overbeek, L., Peelen, M., Popma, J., Postma, G., Roelofs, K., Van Rossenberg, Y. G. T., Schaap, G., Scheepers, P., Selen, L., Starren, M., Swinkels, D. W., Tendolkar, I., Thijssen, D., Timmerman, H., Tutunji, R., Tuladhar, A., Veling, H., Verhagen, M., Verkroost, J., Vink, J., Vriezekolk, V., Vrijsen, J., Vyrastekova, J., Van der Wal, S., Willems, R. M., & Willemsen, A.
(2021). Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context.
PLoS One, 16(12): e0260952. doi:10.1371/journal.pone.0260952.
The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biological, social, and environmental factors is limited. To address this, we designed the Healthy Brain Study (HBS), an interdisciplinary, longitudinal, cohort study based on multidimensional, dynamic assessments in both the laboratory and the real world. Here, we describe the rationale and design of the currently ongoing HBS. The HBS is examining a population-based sample of 1,000 healthy participants (age 30-39) who are thoroughly studied across an entire year. Data are collected through cognitive, affective, behavioral, and physiological testing, neuroimaging, bio-sampling, questionnaires, ecological momentary assessment, and real-world assessments using wearable devices. These data will become an accessible resource for the scientific community enabling the next step in understanding the human brain and how it dynamically and individually operates in its bio-social context. An access procedure to the collected data and bio-samples is in place and published on https://www.healthybrainstudy.nl/en/data-and-methods.
https://www.trialregister.nl/trial/7955
Publication type
Journal article
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