Publications

Abstract

A t(X;1)(p11.2;q21.2) has been reported in cases of papillary renal cell tumors arising in males. In this study two cell lines derived from this tumor type have been used to indicate the breakpoint region on the X chromosome. Both cell lines have the translocation in addition to other rearrangements and one is derived from the first female case to be reported with the t(X;1)(p11.2;q21.2). Fluorescence in situ hybridization (FISH) has been used to position YACs belonging to contigs in the Xp11.2 region relative to the breakpoint. When considered together with detailed mapping information from the Xp11.2 region the position of the breakpoint in both cell lines was suggested as follows: Xpter-->Xp11.23-OATL1-GATA1-WAS-TFE3-SY P-t(X;1)-DXS255-CLCN5-DXS146-OATL2- Xp11.22-->Xcen. The breakpoint was determined to lie in an uncloned region between SYP and a YAC called FTDM/1 which extends 1 Mb distal to DXS255. These results are contrary to the conclusion from previous FISH studies that the breakpoint was near the OATL2 locus, but are consistent with, and considerably refine, the position that had been established by molecular analysis.

Abstract

“Dimensional expressions” single out and describe one symmetric axis of a 1D, 2D, or 3D object (e.g., The road is long). “Bloxes” is an interactive, object-matching task that elicits descriptions of dimensional contrasts between simple geometrical objects (rectangular blocks, rectangular boxes, and cylinders). The aim is to explore the linguistic encoding of dimensions, focusing on features of axis, orientation, flatness/solidity, size and shape. See also 'Suggestions for field research on dimensional expressions' (https://doi.org/10.17617/2.3003382).

Abstract

The aim of this task is to explore the linguistic expression of “dimensions” — e.g., the height, width or depth — of objects in the world around us. In a dimensional expression, one symmetric axis of a 1D, 2D, or 3D object is singled out and described (e.g., That man is tall). Dimensional expressions in different languages show a range of different combinatorial and extensional uses. This document guides the researcher through some spatial situations where contrastive features of dimensional expressions are likely to be observable.

Abstract

This paper presents a cognitive theory on the production and shaping of selfrepairs during speaking. In an extensive experimental study, a new technique is tried out: artificial elicitation of self-repairs. The data clearly indicate that two mechanisms for computing the shape of self-repairs should be distinguished. One is based on the repair strategy called reformulation, the second one on lemma substitution. W. Levelt’s (1983, Cognition, 14, 41- 104) well-formedness rule, which connects self-repairs to coordinate structures, is shown to apply only to reformulations. In case of lemma substitution, a totally different set of rules is at work. The linguistic unit of central importance in reformulations is the major syntactic constituent; in lemma substitutions it is a prosodic unit. the phonological phrase. A parametrization of the model yielded a very satisfactory fit between observed and reconstructed scores.

Abstract

An essential phenomenon in the development towards syntactic maturity after early childhood is the increasing use of so-called sentence-combining transformations. Especially by using subordination, complex sentences are produced. The research reported here is an attempt to arrive at a more adequate characterization and explanation. Our starting point was an analysis of 280 texts written by Dutch-speaking pupils of the two highest grades of the primary school and the four lowest grades of three different types of secondary education. It was examined whether systematic shifts in the use of certain groups of so-called function words could be traced. We concluded that the development of the syntactic formulating ability can be characterized as an increase in connectivity: the use of all kinds of function words which explicitly mark logico-semantic relations between propositions. This development starts by inserting special adverbs and coordinating conjunctions resulting in various types of coordination. In a later stage, the syntactic patterning of the sentence is affected as well (various types of subordination). The increase in sentence complexity is only one aspect of the entire development. An explanation for the increase in connectivity is offered based upon a distinction between narrative and expository language use. The latter, but not the former, is characterized by frequent occurrence of connectives. The development in syntactic formulating ability includes a high level of skill in expository language use. Speed of development is determined by intensity of training, e.g. in scholastic and occupational settings.

Abstract

Dutch words with certain final consonant clusters are subject to optional schwa epenthesis. The present research aimed at investigating how Dutch listeners deal with this type of phonological variation. By means of syllable monitoring experiments, it was investigated whether Dutch listeners process words with epenthetic schwa (e.g., ’balluk’) as bisyllabic words or rather as monosyllabic words. Real words (e.g., ’balk’, ’balluk’) and pseudowords (e.g., ’golk’, ’golluk’) were compared, to examine effects of lexical representation. No difference was found between monitoring times for BAL targets in ’balluk’ carriers as compared to ’balk’ carriers. This suggests that words with epenthetic schwa are not processed as bisyllabic words. The effects for the pseudo-words paralleled those for the real words, which suggests that they are not due to lexical representation but rather to the application of phonological rules.

Abstract

Meermalen is getracht om syntactische formuleenuuirdigheid direct en objectief te meten aan de hand van gesproken of geschreven teksten. Uitgangspunt hierbij vormde in de regel de syntactische complexiteit van de geproduceerde taaluitingen. Dit heeft echter niet geleid tot een plausibele, duidelijk omschreven en praktisch bruikbare index. N.a.v. een kritische bespreking van de notie complexiteit wordt in dit artikel als nieuw criterium voorgesteld de connectiviteit van de taaluitingen; de expliciete aanduiding van logiscli-scmantische relaties tussen proposities. Connectiviteit is gemakkelijk scoorbaar aan de hand van functiewoorden die verschillende vormen van nevenschikkend en onderschikkend zinsverband markeren. Deze nieuwe index ondetrangt de kritiek die op complexiteit gegeven kon worden, blijkt duidelijk te discrimineren tussen groepen leerlingen die van elkaar verschillen naar leeftijd en opleidingsniveau, en sluit aan bij recente taalpsychologische en sociolinguïstische theorie. Tot besluit worden enige onderwijskundige implicaties aangegeven.

Abstract

This chapter explores grammatical gender as a linguistic phenomenon. First, I define gender in terms of agreement, and look at the parts of speech that can take gender agreement. Because it relates to assumptions underlying much psycholinguistic gender research, I also examine the reasons why gender systems are thought to emerge, change, and disappear. Then, I describe the gender system of Dutch. The frequent confusion about the number of genders in Dutch will be resolved by looking at the history of the system, and the role of pronominal reference therein. In addition, I report on three lexical- statistical analyses of the distribution of genders in the language. After having dealt with Dutch, I look at whether the genders of Dutch and other languages are more or less randomly assigned, or whether there is some system to it. In contrast to what many people think, regularities do indeed exist. Native speakers could in principle exploit such regularities to compute rather than memorize gender, at least in part. Although this should be taken into account as a possibility, I will also argue that it is by no means a necessary implication.

Abstract

A combination of Southern blot analysis on a panel of tumor-derived somatic cell hybrids and fluorescence in situ hybridization techniques was used to map YACs, cosmids and DNA markers from the Xp11.2 region relative to the X chromosome breakpoint of the renal cell carcinoma-associated t(X;1)(p11;q21). The position of the breakpoint could be determined as follows: Xcen-OATL2-DXS146-DXS255-SYP-t(X;1)-TFE 3-OATL1-Xpter. Fluorescence in situ hybridization experiments using TFE3-containing YACs and cosmids revealed split signals indicating that the corresponding DNA inserts span the breakpoint region. Subsequent Southern blot analysis showed that a 2.3-kb EcoRI fragment which is present in all TFE3 cosmids identified, hybridizes to aberrant restriction fragments in three independent t(X;1)-positive renal cell carcinoma DNAs. The breakpoints in these tumors are not the same, but map within a region of approximately 6.5 kb. Through preparative gel electrophoresis an (X;1) chimaeric 4.4-kb EcoRI fragment could be isolated which encompasses the breakpoint region present on der(X). Preliminary characterization of this fragment revealed the presence of a 150-bp region with a strong homology to the 5' end of the mouse TFE3 cDNA in the X-chromosome part, and a 48-bp segment in the chromosome 1-derived part identical to the 5' end of a known EST (accession number R93849). These observations suggest that a fusion gene is formed between the two corresponding genes in t(X;1)(p11;q21)-positive papillary renal cell carcinomas.

Abstract

Three experiments examined the time course of phonological encoding in speech production. A new methodology is introduced in which subjects are required to monitor their internal speech production for prespecified target segments and syllables. Experiment 1 demonstrated that word initial target segments are monitored significantly faster than second syllable initial target segments. The addition of a concurrent articulation task (Experiment 1b) had a limited effect on performance, excluding the possibility that subjects are monitoring a subvocal articulation of the carrier word. Moreover, no relationship was observed between the pattern of monitoring latencies and the timing of the targets in subjects′ overt speech. Subjects are not, therefore, monitoring an internal phonetic representation of the carrier word. Experiment 2 used the production monitoring task to replicate the syllable monitoring effect observed in speech perception experiments: responses to targets were faster when they corresponded to the initial syllable of the carrier word than when they did not. We conclude that subjects are monitoring their internal generation of a syllabified phonological representation. Experiment 3 provides more detailed evidence concerning the time course of the generation of this representation by comparing monitoring latencies to targets within, as well as between, syllables. Some amendments to current models of phonological encoding are suggested in light of these results.

Abstract

Field data are drawn from a particular speech community at a certain place and time. The intent of this survey is to enrich understanding of the various socio-cultural contexts in which linguistic and “cognitive” data may have been collected, so that we can explore the role which societal, cultural and contextual factors may play in this material. The questionnaire gives guidelines concerning types of ethnographic information that are important to cross-cultural and cross-linguistic enquiry, and will be especially useful to researchers who do not have specialised training in anthropology.

Abstract

How do languages encode different kinds of movement, and what features do people pay attention to when describing motion events? This document outlines topics concerning the investigation of “enter” and “exit” events. It helps contextualise research tasks that examine this domain (see 'Motion Elicitation' and 'Enter/Exit animation') and gives some pointers about what other questions can be explored.

Abstract

How do languages encode different kinds of movement, and what features do people pay attention to when describing motion events? This task investigates the expression of “enter” and “exit” activities, that is, events involving motion in(to) and motion out (of) container-like items. The researcher first uses particular stimuli (a ball, a cup, rice, etc.) to elicit descriptions of enter/exit events from one consultant, and then asks another consultant to demonstrate the event based on these descriptions. See also the related entries Enter/Exit Animation and Background Questions for Enter/Exit Research.

Abstract

The purpose of this paper is to question some of the basic assumpiions concerning motion verbs. In particular, it examines the assumption that "come" and "go" are lexical universals which manifest a universal deictic Opposition. Against the background offive working hypotheses about the nature of'come" and ''go", this study presents a comparative investigation of t wo unrelated languages—Mparntwe Arrernte (Pama-Nyungan, Australian) and Longgu (Oceanic, Austronesian). Although the pragmatic and deictic "suppositional" complexity of"come" and "go" expressions has long been recognized, we argue that in any given language the analysis of these expressions is much more semantically and systemically complex than has been assumed in the literature. Languages vary at the lexical semantic level äs t o what is entailed by these expressions, äs well äs differing äs t o what constitutes the prototype and categorial structure for such expressions. The data also strongly suggest that, ifthere is a lexical universal "go", then this cannof be an inherently deictic expression. However, due to systemic Opposition with "come", non-deictic "go" expressions often take on a deictic Interpretation through pragmatic attribution. Thus, this crosslinguistic investigation of "come" and "go" highlights the need to consider semantics and pragmatics äs modularly separate.

Abstract

A new psycholinguistically motivated and neural network based model of human word recognition is presented. In contrast to earlier models it uses real speech as input. At the word layer acoustical and temporal information is stored by sequences of connected sensory neurons which pass on sensor potentials to a word neuron. In experiments with a small lexicon which includes groups of very similar word forms, the model meets high standards with respect to word recognition and simulates a number of wellknown psycholinguistical effects.