Publications

Displaying 101 - 200 of 1059
  • Casasanto, D., Willems, R. M., & Hagoort, P. (2009). Body-specific representations of action verbs: Evidence from fMRI in right- and left-handers. In N. Taatgen, & H. Van Rijn (Eds.), Proceedings of the 31st Annual Meeting of the Cognitive Science Society (pp. 875-880). Austin: Cognitive Science Society.

    Abstract

    According to theories of embodied cognition, understanding a verb like throw involves unconsciously simulating the action throwing, using areas of the brain that support motor planning. If understanding action words involves mentally simulating our own actions, then the neurocognitive representation of word meanings should differ for people with different kinds of bodies, who perform actions in systematically different ways. In a test of the body-specificity hypothesis (Casasanto, 2009), we used fMRI to compare premotor activity correlated with action verb understanding in right- and left-handers. Right-handers preferentially activated left premotor cortex during lexical decision on manual action verbs (compared with non-manual action verbs), whereas left-handers preferentially activated right premotor areas. This finding helps refine theories of embodied semantics, suggesting that implicit mental simulation during language processing is body-specific: Right and left-handers, who perform actions differently, use correspondingly different areas of the brain for representing action verb meanings.
  • Casasanto, D. (2009). Embodiment of abstract concepts: Good and bad in right- and left-handers. Journal of Experimental Psychology: General, 138, 351-367. doi:10.1037/a0015854.

    Abstract

    Do people with different kinds of bodies think differently? According to the body-specificity hypothesis, people who interact with their physical environments in systematically different ways should form correspondingly different mental representations. In a test of this hypothesis, 5 experiments investigated links between handedness and the mental representation of abstract concepts with positive or negative valence (e.g., honesty, sadness, intelligence). Mappings from spatial location to emotional valence differed between right- and left-handed participants. Right-handers tended to associate rightward space with positive ideas and leftward space with negative ideas, but left-handers showed the opposite pattern, associating rightward space with negative ideas and leftward with positive ideas. These contrasting mental metaphors for valence cannot be attributed to linguistic experience, because idioms in English associate good with right but not with left. Rather, right- and left-handers implicitly associated positive valence more strongly with the side of space on which they could act more fluently with their dominant hands. These results support the body-specificity hypothesis and provide evidence for the perceptuomotor basis of even the most abstract ideas.
  • Casasanto, D., & Jasmin, K. (2009). Emotional valence is body-specific: Evidence from spontaneous gestures during US presidential debates. In N. Taatgen, & H. Van Rijn (Eds.), Proceedings of the 31st Annual Meeting of the Cognitive Science Society (pp. 1965-1970). Austin: Cognitive Science Society.

    Abstract

    What is the relationship between motor action and emotion? Here we investigated whether people associate good things more strongly with the dominant side of their bodies, and bad things with the non-dominant side. To find out, we analyzed spontaneous gestures during speech expressing ideas with positive or negative emotional valence (e.g., freedom, pain, compassion). Samples of speech and gesture were drawn from the 2004 and 2008 US presidential debates, which involved two left-handers (Obama, McCain) and two right-handers (Kerry, Bush). Results showed a strong association between the valence of spoken clauses and the hands used to make spontaneous co-speech gestures. In right-handed candidates, right-hand gestures were more strongly associated with positive-valence clauses, and left-hand gestures with negative-valence clauses. Left-handed candidates showed the opposite pattern. Right- and left-handers implicitly associated positive valence more strongly with their dominant hand: the hand they can use more fluently. These results support the body-specificity hypothesis, (Casasanto, 2009), and suggest a perceptuomotor basis for even our most abstract ideas.
  • Casasanto, D. (2009). [Review of the book Music, language, and the brain by Aniruddh D. Patel]. Language and Cognition, 1(1), 143-146. doi:10.1515/LANGCOG.2009.007.
  • Casasanto, D., Fotakopoulou, O., & Boroditsky, L. (2009). Space and time in the child's mind: Evidence for a cross-dimensional asymmetry. In N. Taatgen, & H. Van Rijn (Eds.), Proceedings of the 31st Annual Meeting of the Cognitive Science Society (pp. 1090-1095). Austin: Cognitive Science Society.

    Abstract

    What is the relationship between space and time in the human mind? Studies in adults show an asymmetric relationship between mental representations of these basic dimensions of experience: representations of time depend on space more than representations of space depend on time. Here we investigated the relationship between space and time in the developing mind. Native Greek-speaking children (N=99) watched movies of two animals traveling along parallel paths for different distances or durations and judged the spatial and temporal aspects of these events (e.g., Which animal went for a longer time, or a longer distance?) Results showed a reliable cross-dimensional asymmetry: for the same stimuli, spatial information influenced temporal judgments more than temporal information influenced spatial judgments. This pattern was robust to variations in the age of the participants and the type of language used to elicit responses. This finding demonstrates a continuity between space-time representations in children and adults, and informs theories of analog magnitude representation.
  • Casasanto, D. (2009). Space for thinking. In V. Evans, & P. Chilton (Eds.), Language, cognition and space: State of the art and new directions (pp. 453-478). London: Equinox Publishing.
  • Casasanto, D. (2009). When is a linguistic metaphor a conceptual metaphor? In V. Evans, & S. Pourcel (Eds.), New directions in cognitive linguistics (pp. 127-145). Amsterdam: Benjamins.
  • Cavaco, P., Curuklu, B., & Petersson, K. M. (2009). Artificial grammar recognition using two spiking neural networks. Frontiers in Neuroinformatics. Conference abstracts: 2nd INCF Congress of Neuroinformatics. doi:10.3389/conf.neuro.11.2009.08.096.

    Abstract

    In this paper we explore the feasibility of artificial (formal) grammar recognition (AGR) using spiking neural networks. A biologically inspired minicolumn architecture is designed as the basic computational unit. A network topography is defined based on the minicolumn architecture, here referred to as nodes, connected with excitatory and inhibitory connections. Nodes in the network represent unique internal states of the grammar’s finite state machine (FSM). Future work to improve the performance of the networks is discussed. The modeling framework developed can be used by neurophysiological research to implement network layouts and compare simulated performance characteristics to actual subject performance.
  • Çetinçelik, M., Rowland, C. F., & Snijders, T. M. (2023). Ten-month-old infants’ neural tracking of naturalistic speech is not facilitated by the speaker’s eye gaze. Developmental Cognitive Neuroscience, 64: 101297. doi:10.1016/j.dcn.2023.101297.

    Abstract

    Eye gaze is a powerful ostensive cue in infant-caregiver interactions, with demonstrable effects on language acquisition. While the link between gaze following and later vocabulary is well-established, the effects of eye gaze on other aspects of language, such as speech processing, are less clear. In this EEG study, we examined the effects of the speaker’s eye gaze on ten-month-old infants’ neural tracking of naturalistic audiovisual speech, a marker for successful speech processing. Infants watched videos of a speaker telling stories, addressing the infant with direct or averted eye gaze. We assessed infants’ speech-brain coherence at stress (1–1.75 Hz) and syllable (2.5–3.5 Hz) rates, tested for differences in attention by comparing looking times and EEG theta power in the two conditions, and investigated whether neural tracking predicts later vocabulary. Our results showed that infants’ brains tracked the speech rhythm both at the stress and syllable rates, and that infants’ neural tracking at the syllable rate predicted later vocabulary. However, speech-brain coherence did not significantly differ between direct and averted gaze conditions and infants did not show greater attention to direct gaze. Overall, our results suggest significant neural tracking at ten months, related to vocabulary development, but not modulated by speaker’s gaze.

    Additional information

    supplementary material
  • Chan, A., Yang, W., Chang, F., & Kidd, E. (2018). Four-year-old Cantonese-speaking children's online processing of relative clauses: A permutation analysis. Journal of Child Language, 45(1), 174-203. doi:10.1017/s0305000917000198.

    Abstract


    We report on an eye-tracking study that investigated four-year-old Cantonese-speaking children's online processing of subject and object relative clauses (RCs). Children's eye-movements were recorded as they listened to RC structures identifying a unique referent (e.g. “Can you pick up the horse that pushed the pig?”). Two RC types, classifier (CL) and ge3 RCs, were tested in a between-participants design. The two RC types differ in their syntactic analyses and frequency of occurrence, providing an important point of comparison for theories of RC acquisition and processing. A permutation analysis showed that the two structures were processed differently: CL RCs showed a significant object-over-subject advantage, whereas ge3 RCs showed the opposite effect. This study shows that children can have different preferences even for two very similar RC structures within the same language, suggesting that syntactic processing preferences are shaped by the unique features of particular constructions both within and across different linguistic typologies.
  • Chang, F., Tatsumi, T., Hiranuma, Y., & Bannard, C. (2023). Visual heuristics for verb production: Testing a deep‐learning model with experiments in Japanese. Cognitive Science, 47(8): e13324. doi:10.1111/cogs.13324.

    Abstract

    Tense/aspect morphology on verbs is often thought to depend on event features like telicity, but it is not known how speakers identify these features in visual scenes. To examine this question, we asked Japanese speakers to describe computer-generated animations of simple actions with variation in visual features related to telicity. Experiments with adults and children found that they could use goal information in the animations to select appropriate past and progressive verb forms. They also produced a large number of different verb forms. To explain these findings, a deep-learning model of verb production from visual input was created that could produce a human-like distribution of verb forms. It was able to use visual cues to select appropriate tense/aspect morphology. The model predicted that video duration would be related to verb complexity, and past tense production would increase when it received the endpoint as input. These predictions were confirmed in a third study with Japanese adults. This work suggests that verb production could be tightly linked to visual heuristics that support the understanding of events.
  • Chen, C.-h., Zhang, Y., & Yu, C. (2018). Learning object names at different hierarchical levels using cross-situational statistics. Cognitive Science, 42(S2), 591-605. doi:10.1111/cogs.12516.

    Abstract

    Objects in the world usually have names at different hierarchical levels (e.g., beagle, dog, animal). This research investigates adults' ability to use cross-situational statistics to simultaneously learn object labels at individual and category levels. The results revealed that adults were able to use co-occurrence information to learn hierarchical labels in contexts where the labels for individual objects and labels for categories were presented in completely separated blocks, in interleaved blocks, or mixed in the same trial. Temporal presentation schedules significantly affected the learning of individual object labels, but not the learning of category labels. Learners' subsequent generalization of category labels indicated sensitivity to the structure of statistical input.
  • Chen, X. S., Collins, L. J., Biggs, P. J., & Penny, D. (2009). High throughput genome-wide survey of small RNAs from the parasitic protists giardia intestinalis and trichomonas vaginalis. Genome biology and evolution, 1, 165-175. doi:10.1093/gbe/evp017.

    Abstract

    RNA interference (RNAi) is a set of mechanisms which regulate gene expression in eukaryotes. Key elements of RNAi are small sense and antisense RNAs from 19 to 26 nucleotides generated from double-stranded RNAs. miRNAs are a major type of RNAi-associated small RNAs and are found in most eukaryotes studied to date. To investigate whether small RNAs associated with RNAi appear to be present in all eukaryotic lineages, and therefore present in the ancestral eukaryote, we studied two deep-branching protozoan parasites, Giardia intestinalis and Trichomonas vaginalis. Little is known about endogenous small RNAs involved in RNAi of these organisms. Using Illumina Solexa sequencing and genome-wide analysis of small RNAs from these distantly related deep-branching eukaryotes, we identified 10 strong miRNA candidates from Giardia and 11 from Trichomonas. We also found evidence of Giardia siRNAs potentially involved in the expression of variant-specific-surface proteins. In addition, 8 new snoRNAs from Trichomonas are identified. Our results indicate that miRNAs are likely to be general in ancestral eukaryotes, and therefore are likely to be a universal feature of eukaryotes.
  • Chen, A. (2009). Intonation and reference maintenance in Turkish learners of Dutch: A first insight. AILE - Acquisition et Interaction en Langue Etrangère, 28(2), 67-91.

    Abstract

    This paper investigates L2 learners’ use of intonation in reference maintenance in comparison to native speakers at three longitudinal points. Nominal referring expressions were elicited from two untutored Turkish learners of Dutch and five native speakers of Dutch via a film retelling task, and were analysed in terms of pitch span and word duration. Effects of two types of change in information states were examined, between new and given and between new and accessible. We found native-like use of word duration in both types of change early on but different performances between learners and development over time in one learner in the use of pitch span. Further, the use of morphosyntactic devices had different effects on the two learners. The inter-learner differences and late systematic use of pitch span, in spite of similar use of pitch span in learners’ L1 and L2, suggest that learning may play a role in the acquisition of intonation as a device for reference maintenance.
  • Chen, A. (2009). Perception of paralinguistic intonational meaning in a second language. Language Learning, 59(2), 367-409.
  • Chen, A. (2009). The phonetics of sentence-initial topic and focus in adult and child Dutch. In M. Vigário, S. Frota, & M. Freitas (Eds.), Phonetics and Phonology: Interactions and interrelations (pp. 91-106). Amsterdam: Benjamins.
  • Chen, A., Çetinçelik, M., Roncaglia-Denissen, M. P., & Sadakata, M. (2023). Native language, L2 experience, and pitch processing in music. Linguistic Approaches to Bilingualism, 13(2), 218-237. doi:10.1075/lab.20030.che.

    Abstract

    The current study investigated how the role of pitch in one’s native language and L2 experience influenced musical melodic processing by testing Turkish and Mandarin Chinese advanced and beginning learners of English as an L2. Pitch has a lower functional load and shows a simpler pattern in Turkish than in Chinese as the former only contrasts between presence and the absence of pitch elevation, while the latter makes use of four different pitch contours lexically. Using the Musical Ear Test as the tool, we found that the Chinese listeners outperformed the Turkish listeners, and the advanced L2 learners outperformed the beginning learners. The Turkish listeners were further tested on their discrimination of bisyllabic Chinese lexical tones, and again an L2 advantage was observed. No significant difference was found for working memory between the beginning and advanced L2 learners. These results suggest that richness of tonal inventory of the native language is essential for triggering a music processing advantage, and on top of the tone language advantage, the L2 experience yields a further enhancement. Yet, unlike the tone language advantage that seems to relate to pitch expertise, learning an L2 seems to improve sound discrimination in general, and such improvement exhibits in non-native lexical tone discrimination.
  • Chevrefils, L., Morgenstern, A., Beaupoil-Hourdel, P., Bedoin, D., Caët, S., Danet, C., Danino, C., De Pontonx, S., & Parisse, C. (2023). Coordinating eating and languaging: The choreography of speech, sign, gesture and action in family dinners. In W. Pouw, J. Trujillo, H. R. Bosker, L. Drijvers, M. Hoetjes, J. Holler, S. Kadava, L. Van Maastricht, E. Mamus, & A. Ozyurek (Eds.), Gesture and Speech in Interaction (GeSpIn) Conference. doi:10.17617/2.3527183.

    Abstract

    In this study, we analyze one French signing and one French speaking family’s interaction during dinner. The families composed of two parents and two children aged 3 to 11 were filmed with three cameras to capture all family members’ behaviors. The three videos per dinner were synchronized and coded on ELAN. We annotated all participants’ acting, and languaging.
    Our quantitative analyses show how family members collaboratively manage multiple streams of activity through the embodied performances of dining and interacting. We uncover different profiles according to participants’ modality of expression and status (focusing on the mother and the younger child). The hearing participants’ co-activity management illustrates their monitoring of dining and conversing and how they progressively master the affordances of the visual and vocal channels to maintain the simultaneity of the two activities. The deaf mother skillfully manages to alternate smoothly between dining and interacting. The deaf younger child manifests how she is in the process of developing her skills to manage multi-activity. Our qualitative analyses focus on the ecology of visual-gestural and audio-vocal languaging in the context of co-activity according to language and participant. We open new perspectives on the management of gaze and body parts in multimodal languaging.
  • Choi, J., Broersma, M., & Cutler, A. (2018). Phonetic learning is not enhanced by sequential exposure to more than one language. Linguistic Research, 35(3), 567-581. doi:10.17250/khisli.35.3.201812.006.

    Abstract

    Several studies have documented that international adoptees, who in early years have
    experienced a change from a language used in their birth country to a new language
    in an adoptive country, benefit from the limited early exposure to the birth language
    when relearning that language’s sounds later in life. The adoptees’ relearning advantages
    have been argued to be conferred by lasting birth-language knowledge obtained from
    the early exposure. However, it is also plausible to assume that the advantages may
    arise from adoptees’ superior ability to learn language sounds in general, as a result
    of their unusual linguistic experience, i.e., exposure to multiple languages in sequence
    early in life. If this is the case, then the adoptees’ relearning benefits should generalize
    to previously unheard language sounds, rather than be limited to their birth-language
    sounds. In the present study, adult Korean adoptees in the Netherlands and matched
    Dutch-native controls were trained on identifying a Japanese length distinction to which
    they had never been exposed before. The adoptees and Dutch controls did not differ
    on any test carried out before, during, or after the training, indicating that observed
    adoptee advantages for birth-language relearning do not generalize to novel, previously
    unheard language sounds. The finding thus fails to support the suggestion that
    birth-language relearning advantages may arise from enhanced ability to learn language
    sounds in general conferred by early experience in multiple languages. Rather, our
    finding supports the original contention that such advantages involve memory traces
    obtained before adoption
  • Cholin, J., & Levelt, W. J. M. (2009). Effects of syllable preparation and syllable frequency in speech production: Further evidence for syllabic units at a post-lexical level. Language and Cognitive Processes, 24, 662-684. doi:10.1080/01690960802348852.

    Abstract

    In the current paper, we asked at what level in the speech planning process speakers retrieve stored syllables. There is evidence that syllable structure plays an essential role in the phonological encoding of words (e.g., online syllabification and phonological word formation). There is also evidence that syllables are retrieved as whole units. However, findings that clearly pinpoint these effects to specific levels in speech planning are scarce. We used a naming variant of the implicit priming paradigm to contrast voice onset latencies for frequency-manipulated disyllabic Dutch pseudo-words. While prior implicit priming studies only manipulated the item's form and/or syllable structure overlap we introduced syllable frequency as an additional factor. If the preparation effect for syllables obtained in the implicit priming paradigm proceeds beyond phonological planning, i.e., includes the retrieval of stored syllables, then the preparation effect should differ for high- and low frequency syllables. The findings reported here confirm this prediction: Low-frequency syllables benefit significantly more from the preparation than high-frequency syllables. Our findings support the notion of a mental syllabary at a post-lexical level, between the levels of phonological and phonetic encoding.
  • Chu, M., & Kita, S. (2009). Co-speech gestures do not originate from speech production processes: Evidence from the relationship between co-thought and co-speech gestures. In N. Taatgen, & H. Van Rijn (Eds.), Proceedings of the Thirty-First Annual Conference of the Cognitive Science Society (pp. 591-595). Austin, TX: Cognitive Science Society.

    Abstract

    When we speak, we spontaneously produce gestures (co-speech gestures). Co-speech gestures and speech production are closely interlinked. However, the exact nature of the link is still under debate. To addressed the question that whether co-speech gestures originate from the speech production system or from a system independent of the speech production, the present study examined the relationship between co-speech and co-thought gestures. Co-thought gestures, produced during silent thinking without speaking, presumably originate from a system independent of the speech production processes. We found a positive correlation between the production frequency of co-thought and co-speech gestures, regardless the communicative function that co-speech gestures might serve. Therefore, we suggest that co-speech gestures and co-thought gestures originate from a common system that is independent of the speech production processes
  • Clough, S., Morrow, E., Mutlu, B., Turkstra, L., & Duff, M. C. C. (2023). Emotion recognition of faces and emoji in individuals with moderate-severe traumatic brain injury. Brain Injury, 37(7), 596-610. doi:10.1080/02699052.2023.2181401.

    Abstract

    Background. Facial emotion recognition deficits are common after moderate-severe traumatic brain injury (TBI) and linked to poor social outcomes. We examine whether emotion recognition deficits extend to facial expressions depicted by emoji.
    Methods. Fifty-one individuals with moderate-severe TBI (25 female) and fifty-one neurotypical peers (26 female) viewed photos of human faces and emoji. Participants selected the best-fitting label from a set of basic emotions (anger, disgust, fear, sadness, neutral, surprise, happy) or social emotions (embarrassed, remorseful, anxious, neutral, flirting, confident, proud).
    Results. We analyzed the likelihood of correctly labeling an emotion by group (neurotypical, TBI), stimulus condition (basic faces, basic emoji, social emoji), sex (female, male), and their interactions. Participants with TBI did not significantly differ from neurotypical peers in overall emotion labeling accuracy. Both groups had poorer labeling accuracy for emoji compared to faces. Participants with TBI (but not neurotypical peers) had poorer accuracy for labeling social emotions depicted by emoji compared to basic emotions depicted by emoji. There were no effects of participant sex.
    Discussion. Because emotion representation is more ambiguous in emoji than human faces, studying emoji use and perception in TBI is an important consideration for understanding functional communication and social participation after brain injury.
  • Clough, S., & Hilverman, C. (2018). Hand gestures and how they help children learn. Frontiers for Young Minds, 6: 29. doi:10.3389/frym.2018.00029.

    Abstract

    When we talk, we often make hand movements called gestures at the same time. Although just about everyone gestures when they talk, we usually do not even notice the gestures. Our hand gestures play an important role in helping us learn and remember! When we see other people gesturing when they talk—or when we gesture when we talk ourselves—we are more likely to remember the information being talked about than if gestures were not involved. Our hand gestures can even indicate when we are ready to learn new things! In this article, we explain how gestures can help learning. To investigate this, we studied children learning a new mathematical concept called equivalence. We hope that this article will help you notice when you, your friends and family, and your teachers are gesturing, and that it will help you understand how those gestures can help people learn.
  • Clough, S., Padilla, V.-G., Brown-Schmidt, S., & Duff, M. C. (2023). Intact speech-gesture integration in narrative recall by adults with moderate-severe traumatic brain injury. Neuropsychologia, 189: 108665. doi:10.1016/j.neuropsychologia.2023.108665.

    Abstract

    Purpose

    Real-world communication is situated in rich multimodal contexts, containing speech and gesture. Speakers often convey unique information in gesture that is not present in the speech signal (e.g., saying “He searched for a new recipe” while making a typing gesture). We examine the narrative retellings of participants with and without moderate-severe traumatic brain injury across three timepoints over two online Zoom sessions to investigate whether people with TBI can integrate information from co-occurring speech and gesture and if information from gesture persists across delays.

    Methods

    60 participants with TBI and 60 non-injured peers watched videos of a narrator telling four short stories. On key details, the narrator produced complementary gestures that conveyed unique information. Participants retold the stories at three timepoints: immediately after, 20-min later, and one-week later. We examined the words participants used when retelling these key details, coding them as a Speech Match (e.g., “He searched for a new recipe”), a Gesture Match (e.g., “He searched for a new recipe online), or Other (“He looked for a new recipe”). We also examined whether participants produced representative gestures themselves when retelling these details.

    Results

    Despite recalling fewer story details, participants with TBI were as likely as non-injured peers to report information from gesture in their narrative retellings. All participants were more likely to report information from gesture and produce representative gestures themselves one-week later compared to immediately after hearing the story.

    Conclusion

    We demonstrated that speech-gesture integration is intact after TBI in narrative retellings. This finding has exciting implications for the utility of gesture to support comprehension and memory after TBI and expands our understanding of naturalistic multimodal language processing in this population.
  • Clough, S., Tanguay, A. F. N., Mutlu, B., Turkstra, L., & Duff, M. C. (2023). How do individuals with and without traumatic brain injury interpret emoji? Similarities and differences in perceived valence, arousal, and emotion representation. Journal of Nonverbal Communication, 47, 489-511. doi:10.1007/s10919-023-00433-w.

    Abstract

    Impaired facial affect recognition is common after traumatic brain injury (TBI) and linked to poor social outcomes. We explored whether perception of emotions depicted by emoji is also impaired after TBI. Fifty participants with TBI and 50 non-injured peers generated free-text labels to describe emotions depicted by emoji and rated their levels of valence and arousal on nine-point rating scales. We compared how the two groups’ valence and arousal ratings were clustered and examined agreement in the words participants used to describe emoji. Hierarchical clustering of affect ratings produced four emoji clusters in the non-injured group and three emoji clusters in the TBI group. Whereas the non-injured group had a strongly positive and a moderately positive cluster, the TBI group had a single positive valence cluster, undifferentiated by arousal. Despite differences in cluster numbers, hierarchical structures of the two groups’ emoji ratings were significantly correlated. Most emoji had high agreement in the words participants with and without TBI used to describe them. Participants with TBI perceived emoji similarly to non-injured peers, used similar words to describe emoji, and rated emoji similarly on the valence dimension. Individuals with TBI showed small differences in perceived arousal for a minority of emoji. Overall, results suggest that basic recognition processes do not explain challenges in computer-mediated communication reported by adults with TBI. Examining perception of emoji in context by people with TBI is an essential next step for advancing our understanding of functional communication in computer-mediated contexts after brain injury.

    Additional information

    supplementary information
  • Collins, L. J., & Chen, X. S. (2009). Ancestral RNA: The RNA biology of the eukaryotic ancestor. RNA Biology, 6(5), 495-502. doi:10.4161/rna.6.5.9551.

    Abstract

    Our knowledge of RNA biology within eukaryotes has exploded over the last five years. Within new research we see that some features that were once thought to be part of multicellular life have now been identified in several protist lineages. Hence, it is timely to ask which features of eukaryote RNA biology are ancestral to all eukaryotes. We focus on RNA-based regulation and epigenetic mechanisms that use small regulatory ncRNAs and long ncRNAs, to highlight some of the many questions surrounding eukaryotic ncRNA evolution.
  • Coopmans, C. W. (2023). Triangles in the brain: The role of hierarchical structure in language use. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Coopmans, C. W., Struiksma, M. E., Coopmans, P. H. A., & Chen, A. (2023). Processing of grammatical agreement in the face of variation in lexical stress: A mismatch negativity study. Language and Speech, 66(1), 202-213. doi:10.1177/00238309221098116.

    Abstract

    Previous electroencephalography studies have yielded evidence for automatic processing of syntax and lexical stress. However, these studies looked at both effects in isolation, limiting their generalizability to everyday language comprehension. In the current study, we investigated automatic processing of grammatical agreement in the face of variation in lexical stress. Using an oddball paradigm, we measured the Mismatch Negativity (MMN) in Dutch-speaking participants while they listened to Dutch subject–verb sequences (linguistic context) or acoustically similar sequences in which the subject was replaced by filtered noise (nonlinguistic context). The verb forms differed in the inflectional suffix, rendering the subject–verb sequences grammatically correct or incorrect, and leading to a difference in the stress pattern of the verb forms. We found that the MMNs were modulated in both the linguistic and nonlinguistic condition, suggesting that the processing load induced by variation in lexical stress can hinder early automatic processing of grammatical agreement. However, as the morphological differences between the verb forms correlated with differences in number of syllables, an interpretation in terms of the prosodic structure of the sequences cannot be ruled out. Future research is needed to determine which of these factors (i.e., lexical stress, syllabic structure) most strongly modulate early syntactic processing.

    Additional information

    supplementary material
  • Coopmans, C. W., Mai, A., Slaats, S., Weissbart, H., & Martin, A. E. (2023). What oscillations can do for syntax depends on your theory of structure building. Nature Reviews Neuroscience, 24, 723. doi:10.1038/s41583-023-00734-5.
  • Coopmans, C. W., Kaushik, K., & Martin, A. E. (2023). Hierarchical structure in language and action: A formal comparison. Psychological Review, 130(4), 935-952. doi:10.1037/rev0000429.

    Abstract

    Since the cognitive revolution, language and action have been compared as cognitive systems, with cross-domain convergent views recently gaining renewed interest in biology, neuroscience, and cognitive science. Language and action are both combinatorial systems whose mode of combination has been argued to be hierarchical, combining elements into constituents of increasingly larger size. This structural similarity has led to the suggestion that they rely on shared cognitive and neural resources. In this article, we compare the conceptual and formal properties of hierarchy in language and action using set theory. We show that the strong compositionality of language requires a particular formalism, a magma, to describe the algebraic structure corresponding to the set of hierarchical structures underlying sentences. When this formalism is applied to actions, it appears to be both too strong and too weak. To overcome these limitations, which are related to the weak compositionality and sequential nature of action structures, we formalize the algebraic structure corresponding to the set of actions as a trace monoid. We aim to capture the different system properties of language and action in terms of the distinction between hierarchical sets and hierarchical sequences and discuss the implications for the way both systems could be represented in the brain.
  • Corcoran, A. W., Alday, P. M., Schlesewsky, M., & Bornkessel-Schlesewsky, I. (2018). Toward a reliable, automated method of individual alpha frequency (IAF) quantification. Psychophysiology, 55(7): e13064. doi:10.1111/psyp.13064.

    Abstract

    Individual alpha frequency (IAF) is a promising electrophysiological marker of interindividual differences in cognitive function. IAF has been linked with trait-like differences in information processing and general intelligence, and provides an empirical basis for the definition of individualized frequency bands. Despite its widespread application, however, there is little consensus on the optimal method for estimating IAF, and many common approaches are prone to bias and inconsistency. Here, we describe an automated strategy for deriving two of the most prevalent IAF estimators in the literature: peak alpha frequency (PAF) and center of gravity (CoG). These indices are calculated from resting-state power spectra that have been smoothed using a Savitzky-Golay filter (SGF). We evaluate the performance characteristics of this analysis procedure in both empirical and simulated EEG data sets. Applying the SGF technique to resting-state data from n = 63 healthy adults furnished 61 PAF and 62 CoG estimates. The statistical properties of these estimates were consistent with previous reports. Simulation analyses revealed that the SGF routine was able to reliably extract target alpha components, even under relatively noisy spectral conditions. The routine consistently outperformed a simpler method of automated peak detection that did not involve spectral smoothing. The SGF technique is fast, open source, and available in two popular programming languages (MATLAB, Python), and thus can easily be integrated within the most popular M/EEG toolsets (EEGLAB, FieldTrip, MNE-Python). As such, it affords a convenient tool for improving the reliability and replicability of future IAF-related research.

    Additional information

    psyp13064-sup-0001-s01.docx
  • Corps, R. E., Liao, M., & Pickering, M. J. (2023). Evidence for two stages of prediction in non-native speakers: A visual-world eye-tracking study. Bilingualism: Language and Cognition, 26(1), 231-243. doi:10.1017/S1366728922000499.

    Abstract

    Comprehenders predict what a speaker is likely to say when listening to non-native (L2) and native (L1) utterances. But what are the characteristics of L2 prediction, and how does it relate to L1 prediction? We addressed this question in a visual-world eye-tracking experiment, which tested when L2 English comprehenders integrated perspective into their predictions. Male and female participants listened to male and female speakers producing sentences (e.g., I would like to wear the nice…) about stereotypically masculine (target: tie; distractor: drill) and feminine (target: dress; distractor: hairdryer) objects. Participants predicted associatively, fixating objects semantically associated with critical verbs (here, the tie and the dress). They also predicted stereotypically consistent objects (e.g., the tie rather than the dress, given the male speaker). Consistent predictions were made later than associative predictions, and were delayed for L2 speakers relative to L1 speakers. These findings suggest prediction involves both automatic and non-automatic stages.
  • Corps, R. E. (2018). Coordinating utterances during conversational dialogue: The role of content and timing predictions. PhD Thesis, The University of Edinburgh, Edinburgh.
  • Corps, R. E., Gambi, C., & Pickering, M. J. (2018). Coordinating utterances during turn-taking: The role of prediction, response preparation, and articulation. Discourse processes, 55(2, SI), 230-240. doi:10.1080/0163853X.2017.1330031.

    Abstract

    During conversation, interlocutors rapidly switch between speaker and listener
    roles and take turns at talk. How do they achieve such fine coordination?
    Most research has concentrated on the role of prediction, but listeners
    must also prepare a response in advance (assuming they wish to respond)
    and articulate this response at the appropriate moment. Such mechanisms
    may overlap with the processes of comprehending the speaker’s incoming
    turn and predicting its end. However, little is known about the stages of
    response preparation and production. We discuss three questions pertaining
    to such stages: (1) Do listeners prepare their own response in advance?,
    (2) Can listeners buffer their prepared response?, and (3) Does buffering
    lead to interference with concurrent comprehension? We argue that fine
    coordination requires more than just an accurate prediction of the interlocutor’s
    incoming turn: Listeners must also simultaneously prepare their own
    response.
  • Corps, R. E., Crossley, A., Gambi, C., & Pickering, M. J. (2018). Early preparation during turn-taking: Listeners use content predictions to determine what to say but not when to say it. Cognition, 175, 77-95. doi:10.1016/j.cognition.2018.01.015.

    Abstract

    During conversation, there is often little gap between interlocutors’ utterances. In two pairs of experiments, we manipulated the content predictability of yes/no questions to investigate whether listeners achieve such coordination by (i) preparing a response as early as possible or (ii) predicting the end of the speaker’s turn. To assess these two mechanisms, we varied the participants’ task: They either pressed a button when they thought the question was about to end (Experiments 1a and 2a), or verbally answered the questions with either yes or no (Experiments 1b and 2b). Predictability effects were present when participants had to prepare a verbal response, but not when they had to predict the turn-end. These findings suggest content prediction facilitates turn-taking because it allows listeners to prepare their own response early, rather than because it helps them predict when the speaker will reach the end of their turn.

    Additional information

    Supplementary material
  • Corps, R. E. (2023). What do we know about the mechanisms of response planning in dialog? In Psychology of Learning and Motivation (pp. 41-81). doi:10.1016/bs.plm.2023.02.002.

    Abstract

    During dialog, interlocutors take turns at speaking with little gap or overlap between their contributions. But language production in monolog is comparatively slow. Theories of dialog tend to agree that interlocutors manage these timing demands by planning a response early, before the current speaker reaches the end of their turn. In the first half of this chapter, I review experimental research supporting these theories. But this research also suggests that planning a response early, while simultaneously comprehending, is difficult. Does response planning need to be this difficult during dialog? In other words, is early-planning always necessary? In the second half of this chapter, I discuss research that suggests the answer to this question is no. In particular, corpora of natural conversation demonstrate that speakers do not directly respond to the immediately preceding utterance of their partner—instead, they continue an utterance they produced earlier. This parallel talk likely occurs because speakers are highly incremental and plan only part of their utterance before speaking, leading to pauses, hesitations, and disfluencies. As a result, speakers do not need to engage in extensive advance planning. Thus, laboratory studies do not provide a full picture of language production in dialog, and further research using naturalistic tasks is needed.
  • Corps, R. E., & Meyer, A. S. (2023). Word frequency has similar effects in picture naming and gender decision: A failure to replicate Jescheniak and Levelt (1994). Acta Psychologica, 241: 104073. doi:10.1016/j.actpsy.2023.104073.

    Abstract

    Word frequency plays a key role in theories of lexical access, which assume that the word frequency effect (WFE, faster access to high-frequency than low-frequency words) occurs as a result of differences in the representation and processing of the words. In a seminal paper, Jescheniak and Levelt (1994) proposed that the WFE arises during the retrieval of word forms, rather than the retrieval of their syntactic representations (their lemmas) or articulatory commands. An important part of Jescheniak and Levelt's argument was that they found a stable WFE in a picture naming task, which requires complete lexical access, but not in a gender decision task, which only requires access to the words' lemmas and not their word forms. We report two attempts to replicate this pattern, one with new materials, and one with Jescheniak and Levelt's orginal pictures. In both studies we found a strong WFE when the pictures were shown for the first time, but much weaker effects on their second and third presentation. Importantly these patterns were seen in both the picture naming and the gender decision tasks, suggesting that either word frequency does not exclusively affect word form retrieval, or that the gender decision task does not exclusively tap lemma access.

    Additional information

    raw data and analysis scripts
  • Corps, R. E., Yang, F., & Pickering, M. (2023). Evidence against egocentric prediction during language comprehension. Royal Society Open Science, 10(12): 231252. doi:10.1098/rsos.231252.

    Abstract

    Although previous research has demonstrated that language comprehension can be egocentric, there is little evidence for egocentricity during prediction. In particular, comprehenders do not appear to predict egocentrically when the context makes it clear what the speaker is likely to refer to. But do comprehenders predict egocentrically when the context does not make it clear? We tested this hypothesis using a visual-world eye-tracking paradigm, in which participants heard sentences containing the gender-neutral pronoun They (e.g. They would like to wear…) while viewing four objects (e.g. tie, dress, drill, hairdryer). Two of these objects were plausible targets of the verb (tie and dress), and one was stereotypically compatible with the participant's gender (tie if the participant was male; dress if the participant was female). Participants rapidly fixated targets more than distractors, but there was no evidence that participants ever predicted egocentrically, fixating objects stereotypically compatible with their own gender. These findings suggest that participants do not fall back on their own egocentric perspective when predicting, even when they know that context does not make it clear what the speaker is likely to refer to.
  • Corradi, Z., Khan, M., Hitti-Malin, R., Mishra, K., Whelan, L., Cornelis, S. S., ABCA4-Study Group, Hoyng, C. B., Kämpjärvi, K., Klaver, C. C. W., Liskova, P., Stohr, H., Weber, B. H. F., Banfi, S., Farrar, G. J., Sharon, D., Zernant, J., Allikmets, R., Dhaenens, C.-M., & Cremers, F. P. M. (2023). Targeted sequencing and in vitro splice assays shed light on ABCA4-associated retinopathies missing heritability. Human Genetics and Genomics Advances, 4(4): 100237. doi:10.1016/j.xhgg.2023.100237.

    Abstract

    The ABCA4 gene is the most frequently mutated Mendelian retinopathy-associated gene. Biallelic variants lead to a variety of phenotypes, however, for thousands of cases the underlying variants remain unknown. Here, we aim to shed further light on the missing heritability of ABCA4-associated retinopathy by analyzing a large cohort of macular dystrophy probands. A total of 858 probands were collected from 26 centers, of whom 722 carried no or one pathogenic ABCA4 variant while 136 cases carried two ABCA4 alleles, one of which was a frequent mild variant, suggesting that deep-intronic variants (DIVs) or other cis-modifiers might have been missed. After single molecule molecular inversion probes (smMIPs)-based sequencing of the complete 128-kb ABCA4 locus, the effect of putative splice variants was assessed in vitro by midigene splice assays in HEK293T cells. The breakpoints of copy number variants (CNVs) were determined by junction PCR and Sanger sequencing. ABCA4 sequence analysis solved 207/520 (39.8%) naïve or unsolved cases and 70/202 (34.7%) monoallelic cases, while additional causal variants were identified in 54/136 (39.7%) of probands carrying two variants. Seven novel DIVs and six novel non-canonical splice site variants were detected in a total of 35 alleles and characterized, including the c.6283-321C>G variant leading to a complex splicing defect. Additionally, four novel CNVs were identified and characterized in five alleles. These results confirm that smMIPs-based sequencing of the complete ABCA4 gene provides a cost-effective method to genetically solve retinopathy cases and that several rare structural and splice altering defects remain undiscovered in STGD1 cases.
  • Coventry, K. R., Gudde, H. B., Diessel, H., Collier, J., Guijarro-Fuentes, P., Vulchanova, M., Vulchanov, V., Todisco, E., Reile, M., Breunesse, M., Plado, H., Bohnemeyer, J., Bsili, R., Caldano, M., Dekova, R., Donelson, K., Forker, D., Park, Y., Pathak, L. S., Peeters, D. and 25 moreCoventry, K. R., Gudde, H. B., Diessel, H., Collier, J., Guijarro-Fuentes, P., Vulchanova, M., Vulchanov, V., Todisco, E., Reile, M., Breunesse, M., Plado, H., Bohnemeyer, J., Bsili, R., Caldano, M., Dekova, R., Donelson, K., Forker, D., Park, Y., Pathak, L. S., Peeters, D., Pizzuto, G., Serhan, B., Apse, L., Hesse, F., Hoang, L., Hoang, P., Igari, Y., Kapiley, K., Haupt-Khutsishvili, T., Kolding, S., Priiki, K., Mačiukaitytė, I., Mohite, V., Nahkola, T., Tsoi, S. Y., Williams, S., Yasuda, S., Cangelosi, A., Duñabeitia, J. A., Mishra, R. K., Rocca, R., Šķilters, J., Wallentin, M., Žilinskaitė-Šinkūnienė, E., & Incel, O. D. (2023). Spatial communication systems across languages reflect universal action constraints. Nature Human Behaviour, 77, 2099-2110. doi:10.1038/s41562-023-01697-4.

    Abstract

    The extent to which languages share properties reflecting the non-linguistic constraints of the speakers who speak them is key to the debate regarding the relationship between language and cognition. A critical case is spatial communication, where it has been argued that semantic universals should exist, if anywhere. Here, using an experimental paradigm able to separate variation within a language from variation between languages, we tested the use of spatial demonstratives—the most fundamental and frequent spatial terms across languages. In n = 874 speakers across 29 languages, we show that speakers of all tested languages use spatial demonstratives as a function of being able to reach or act on an object being referred to. In some languages, the position of the addressee is also relevant in selecting between demonstrative forms. Commonalities and differences across languages in spatial communication can be understood in terms of universal constraints on action shaping spatial language and cognition.
  • Cox, C., Bergmann, C., Fowler, E., Keren-Portnoy, T., Roepstorff, A., Bryant, G., & Fusaroli, R. (2023). A systematic review and Bayesian meta-analysis of the acoustic features of infant-directed speech. Nature Human Behaviour, 7, 114-133. doi:10.1038/s41562-022-01452-1.

    Abstract

    When speaking to infants, adults often produce speech that differs systematically from that directed to other adults. In order to quantify the acoustic properties of this speech style across a wide variety of languages and cultures, we extracted results from empirical studies on the acoustic features of infant-directed speech (IDS). We analyzed data from 88 unique studies (734 effect sizes) on the following five acoustic parameters that have been systematically examined in the literature: i) fundamental frequency (fo), ii) fo variability, iii) vowel space area, iv) articulation rate, and v) vowel duration. Moderator analyses were conducted in hierarchical Bayesian robust regression models in order to examine how these features change with infant age and differ across languages, experimental tasks and recording environments. The moderator analyses indicated that fo, articulation rate, and vowel duration became more similar to adult-directed speech (ADS) over time, whereas fo variability and vowel space area exhibited stability throughout development. These results point the way for future research to disentangle different accounts of the functions and learnability of IDS by conducting theory-driven comparisons among different languages and using computational models to formulate testable predictions.

    Additional information

    supplementary information
  • Creemers, A. (2023). Morphological processing in spoken-word recognition. In D. Crepaldi (Ed.), Linguistic morphology in the mind and brain (pp. 50-64). New York: Routledge.

    Abstract

    Most psycholinguistic studies on morphological processing have examined the role of morphological structure in the visual modality. This chapter discusses morphological processing in the auditory modality, which is an area of research that has only recently received more attention. It first discusses why results in the visual modality cannot straightforwardly be applied to the processing of spoken words, stressing the importance of acknowledging potential modality effects. It then gives a brief overview of the existing research on the role of morphology in the auditory modality, for which an increasing number of studies report that listeners show sensitivity to morphological structure. Finally, the chapter highlights insights gained by looking at morphological processing not only in reading, but also in listening, and it discusses directions for future research
  • Creemers, A., Don, J., & Fenger, P. (2018). Some affixes are roots, others are heads. Natural Language & Linguistic Theory, 36(1), 45-84. doi:10.1007/s11049-017-9372-1.

    Abstract

    A recent debate in the morphological literature concerns the status of derivational affixes. While some linguists (Marantz 1997, 2001; Marvin 2003) consider derivational affixes a type of functional morpheme that realizes a categorial head, others (Lowenstamm 2015; De Belder 2011) argue that derivational affixes are roots. Our proposal, which finds its empirical basis in a study of Dutch derivational affixes, takes a middle position. We argue that there are two types of derivational affixes: some that are roots (i.e. lexical morphemes) and others that are categorial heads (i.e. functional morphemes). Affixes that are roots show ‘flexible’ categorial behavior, are subject to ‘lexical’ phonological rules, and may trigger idiosyncratic meanings. Affixes that realize categorial heads, on the other hand, are categorially rigid, do not trigger ‘lexical’ phonological rules nor allow for idiosyncrasies in their interpretation.
  • Cristia, A., Ganesh, S., Casillas, M., & Ganapathy, S. (2018). Talker diarization in the wild: The case of child-centered daylong audio-recordings. In Proceedings of Interspeech 2018 (pp. 2583-2587). doi:10.21437/Interspeech.2018-2078.

    Abstract

    Speaker diarization (answering 'who spoke when') is a widely researched subject within speech technology. Numerous experiments have been run on datasets built from broadcast news, meeting data, and call centers—the task sometimes appears close to being solved. Much less work has begun to tackle the hardest diarization task of all: spontaneous conversations in real-world settings. Such diarization would be particularly useful for studies of language acquisition, where researchers investigate the speech children produce and hear in their daily lives. In this paper, we study audio gathered with a recorder worn by small children as they went about their normal days. As a result, each child was exposed to different acoustic environments with a multitude of background noises and a varying number of adults and peers. The inconsistency of speech and noise within and across samples poses a challenging task for speaker diarization systems, which we tackled via retraining and data augmentation techniques. We further studied sources of structured variation across raw audio files, including the impact of speaker type distribution, proportion of speech from children, and child age on diarization performance. We discuss the extent to which these findings might generalize to other samples of speech in the wild.
  • Croijmans, I. (2018). Wine expertise shapes olfactory language and cognition. PhD Thesis, Radboud University, Nijmegen.
  • Cronin, K. A., Schroeder, K. K. E., Rothwell, E. S., Silk, J. B., & Snowdon, C. T. (2009). Cooperatively breeding cottontop tamarins (Saguinus oedipus) do not donate rewards to their long-term mates. Journal of Comparative Psychology, 123(3), 231-241. doi:10.1037/a0015094.

    Abstract

    This study tested the hypothesis that cooperative breeding facilitates the emergence of prosocial behavior by presenting cottontop tamarins (Saguinus oedipus) with the option to provide food rewards to pair-bonded mates. In Experiment 1, tamarins could provide rewards to mates at no additional cost while obtaining rewards for themselves. Contrary to the hypothesis, tamarins did not demonstrate a preference to donate rewards, behaving similar to chimpanzees in previous studies. In Experiment 2, the authors eliminated rewards for the donor for a stricter test of prosocial behavior, while reducing separation distress and food preoccupation. Again, the authors found no evidence for a donation preference. Furthermore, tamarins were significantly less likely to deliver rewards to mates when the mate displayed interest in the reward. The results of this study contrast with those recently reported for cooperatively breeding common marmosets, and indicate that prosocial preferences in a food donation task do not emerge in all cooperative breeders. In previous studies, cottontop tamarins have cooperated and reciprocated to obtain food rewards; the current findings sharpen understanding of the boundaries of cottontop tamarins’ food-provisioning behavior.
  • Croxson, P., Forkel, S. J., Cerliani, L., & Thiebaut De Schotten, M. (2018). Structural Variability Across the Primate Brain: A Cross-Species Comparison. Cerebral Cortex, 28(11), 3829-3841. doi:10.1093/cercor/bhx244.

    Abstract

    A large amount of variability exists across human brains; revealed initially on a small scale by postmortem studies and,
    more recently, on a larger scale with the advent of neuroimaging. Here we compared structural variability between human
    and macaque monkey brains using grey and white matter magnetic resonance imaging measures. The monkey brain was
    overall structurally as variable as the human brain, but variability had a distinct distribution pattern, with some key areas
    showing high variability. We also report the first evidence of a relationship between anatomical variability and evolutionary
    expansion in the primate brain. This suggests a relationship between variability and stability, where areas of low variability
    may have evolved less recently and have more stability, while areas of high variability may have evolved more recently and
    be less similar across individuals. We showed specific differences between the species in key areas, including the amount of
    hemispheric asymmetry in variability, which was left-lateralized in the human brain across several phylogenetically recent
    regions. This suggests that cerebral variability may be another useful measure for comparison between species and may add
    another dimension to our understanding of evolutionary mechanisms.
  • Ip, M. H. K., & Cutler, A. (2018). Asymmetric efficiency of juncture perception in L1 and L2. In K. Klessa, J. Bachan, A. Wagner, M. Karpiński, & D. Śledziński (Eds.), Proceedings of Speech Prosody 2018 (pp. 289-296). Baixas, France: ISCA. doi:10.21437/SpeechProsody.2018-59.

    Abstract

    In two experiments, Mandarin listeners resolved potential syntactic ambiguities in spoken utterances in (a) their native language (L1) and (b) English which they had learned as a second language (L2). A new disambiguation task was used, requiring speeded responses to select the correct meaning for structurally ambiguous sentences. Importantly, the ambiguities used in the study are identical in Mandarin and in English, and production data show that prosodic disambiguation of this type of ambiguity is also realised very similarly in the two languages. The perceptual results here showed however that listeners’ response patterns differed for L1 and L2, although there was a significant increase in similarity between the two response patterns with increasing exposure to the L2. Thus identical ambiguity and comparable disambiguation patterns in L1 and L2 do not lead to immediate application of the appropriate L1 listening strategy to L2; instead, it appears that such a strategy may have to be learned anew for the L2.
  • Ip, M. H. K., & Cutler, A. (2018). Cue equivalence in prosodic entrainment for focus detection. In J. Epps, J. Wolfe, J. Smith, & C. Jones (Eds.), Proceedings of the 17th Australasian International Conference on Speech Science and Technology (pp. 153-156).

    Abstract

    Using a phoneme detection task, the present series of
    experiments examines whether listeners can entrain to
    different combinations of prosodic cues to predict where focus
    will fall in an utterance. The stimuli were recorded by four
    female native speakers of Australian English who happened to
    have used different prosodic cues to produce sentences with
    prosodic focus: a combination of duration cues, mean and
    maximum F0, F0 range, and longer pre-target interval before
    the focused word onset, only mean F0 cues, only pre-target
    interval, and only duration cues. Results revealed that listeners
    can entrain in almost every condition except for where
    duration was the only reliable cue. Our findings suggest that
    listeners are flexible in the cues they use for focus processing.
  • Cutler, A., & Butterfield, S. (1990). Durational cues to word boundaries in clear speech. Speech Communication, 9, 485-495.

    Abstract

    One of a listener’s major tasks in understanding continuous speech in segmenting the speech signal into separate words. When listening conditions are difficult, speakers can help listeners by deliberately clear speech. We found that speakers do indeed attempt to makr word boundaries; moreover, they differentiate between word boundaries in a way which suggest they are sensitive to listener needs. Application of heuristic segmentation strategies makes word boundaries before strong syllables easiest for listeners to perceive; but under difficult listening conditions speakers pay more attention to marking word boundaries before weak syllables, i.e. they mark those boundaries which are otherwise particularly hard to perceive.
  • Cutler, A., McQueen, J. M., & Robinson, K. (1990). Elizabeth and John: Sound patterns of men’s and women’s names. Journal of Linguistics, 26, 471-482. doi:10.1017/S0022226700014754.
  • Cutler, A. (1980). Errors of stress and intonation. In V. A. Fromkin (Ed.), Errors in linguistic performance: Slips of the tongue, ear, pen and hand (pp. 67-80). New York: Academic Press.
  • Cutler, A., Burchfield, L. A., & Antoniou, M. (2018). Factors affecting talker adaptation in a second language. In J. Epps, J. Wolfe, J. Smith, & C. Jones (Eds.), Proceedings of the 17th Australasian International Conference on Speech Science and Technology (pp. 33-36).

    Abstract

    Listeners adapt rapidly to previously unheard talkers by
    adjusting phoneme categories using lexical knowledge, in a
    process termed lexically-guided perceptual learning. Although
    this is firmly established for listening in the native language
    (L1), perceptual flexibility in second languages (L2) is as yet
    less well understood. We report two experiments examining L1
    and L2 perceptual learning, the first in Mandarin-English late
    bilinguals, the second in Australian learners of Mandarin. Both
    studies showed stronger learning in L1; in L2, however,
    learning appeared for the English-L1 group but not for the
    Mandarin-L1 group. Phonological mapping differences from
    the L1 to the L2 are suggested as the reason for this result.
  • Cutler, A. (1990). From performance to phonology: Comments on Beckman and Edwards's paper. In J. Kingston, & M. Beckman (Eds.), Papers in laboratory phonology I: Between the grammar and physics of speech (pp. 208-214). Cambridge: Cambridge University Press.
  • Cutler, A. (1980). La leçon des lapsus. La Recherche, 11(112), 686-692.
  • Cutler, A. (2009). Greater sensitivity to prosodic goodness in non-native than in native listeners. Journal of the Acoustical Society of America, 125, 3522-3525. doi:10.1121/1.3117434.

    Abstract

    English listeners largely disregard suprasegmental cues to stress in recognizing words. Evidence for this includes the demonstration of Fear et al. [J. Acoust. Soc. Am. 97, 1893–1904 (1995)] that cross-splicings are tolerated between stressed and unstressed full vowels (e.g., au- of autumn, automata). Dutch listeners, however, do exploit suprasegmental stress cues in recognizing native-language words. In this study, Dutch listeners were presented with English materials from the study of Fear et al. Acceptability ratings by these listeners revealed sensitivity to suprasegmental mismatch, in particular, in replacements of unstressed full vowels by higher-stressed vowels, thus evincing greater sensitivity to prosodic goodness than had been shown by the original native listener group.
  • Cutler, A., & Farrell, J. (2018). Listening in first and second language. In J. I. Liontas (Ed.), The TESOL encyclopedia of language teaching. New York: Wiley. doi:10.1002/9781118784235.eelt0583.

    Abstract

    Listeners' recognition of spoken language involves complex decoding processes: The continuous speech stream must be segmented into its component words, and words must be recognized despite great variability in their pronunciation (due to talker differences, or to influence of phonetic context, or to speech register) and despite competition from many spuriously present forms supported by the speech signal. L1 listeners deal more readily with all levels of this complexity than L2 listeners. Fortunately, the decoding processes necessary for competent L2 listening can be taught in the classroom. Evidence-based methodologies targeted at the development of efficient speech decoding include teaching of minimal pairs, of phonotactic constraints, and of reduction processes, as well as the use of dictation and L2 video captions.
  • Cutler, A. (1990). Exploiting prosodic probabilities in speech segmentation. In G. Altmann (Ed.), Cognitive models of speech processing: Psycholinguistic and computational perspectives (pp. 105-121). Cambridge, MA: MIT Press.
  • Cutler, A., Davis, C., & Kim, J. (2009). Non-automaticity of use of orthographic knowledge in phoneme evaluation. In Proceedings of the 10th Annual Conference of the International Speech Communication Association (Interspeech 2009) (pp. 380-383). Causal Productions Pty Ltd.

    Abstract

    Two phoneme goodness rating experiments addressed the role of orthographic knowledge in the evaluation of speech sounds. Ratings for the best tokens of /s/ were higher in words spelled with S (e.g., bless) than in words where /s/ was spelled with C (e.g., voice). This difference did not appear for analogous nonwords for which every lexical neighbour had either S or C spelling (pless, floice). Models of phonemic processing incorporating obligatory influence of lexical information in phonemic processing cannot explain this dissociation; the data are consistent with models in which phonemic decisions are not subject to necessary top-down lexical influence.
  • Cutler, A. (1980). Productivity in word formation. In J. Kreiman, & A. E. Ojeda (Eds.), Papers from the Sixteenth Regional Meeting, Chicago Linguistic Society (pp. 45-51). Chicago, Ill.: CLS.
  • Cutler, A. (2009). Psycholinguistics in our time. In P. Rabbitt (Ed.), Inside psychology: A science over 50 years (pp. 91-101). Oxford: Oxford University Press.
  • Cutler, A., & Scott, D. R. (1990). Speaker sex and perceived apportionment of talk. Applied Psycholinguistics, 11, 253-272. doi:10.1017/S0142716400008882.

    Abstract

    It is a widely held belief that women talk more than men; but experimental evidence has suggested that this belief is mistaken. The present study investigated whether listener bias contributes to this mistake. Dialogues were recorded in mixed-sex and single-sex versions, and male and female listeners judged the proportions of talk contributed to the dialogues by each participant. Female contributions to mixed-sex dialogues were rated as greater than male contributions by both male and female listeners. Female contributions were more likely to be overestimated when they were speaking a dialogue part perceived as probably female than when they were speaking a dialogue part perceived as probably male. It is suggested that the misestimates are due to a complex of factors that may involve both perceptual effects such as misjudgment of rates of speech and sociological effects such as attitudes to social roles and perception of power relations.
  • Cutler, A. (1990). Syllabic lengthening as a word boundary cue. In R. Seidl (Ed.), Proceedings of the 3rd Australian International Conference on Speech Science and Technology (pp. 324-328). Canberra: Australian Speech Science and Technology Association.

    Abstract

    Bisyllabic sequences which could be interpreted as one word or two were produced in sentence contexts by a trained speaker, and syllabic durations measured. Listeners judged whether the bisyllables, excised from context, were one word or two. The proportion of two-word choices correlated positively with measured duration, but only for bisyllables stressed on the second syllable. The results may suggest a limit for listener sensitivity to syllabic lengthening as a word boundary cue.
  • Cutler, A. (1980). Syllable omission errors and isochrony. In H. W. Dechet, & M. Raupach (Eds.), Temporal variables in speech: studies in honour of Frieda Goldman-Eisler (pp. 183-190). The Hague: Mouton.
  • Cutler, A., & Isard, S. D. (1980). The production of prosody. In B. Butterworth (Ed.), Language production (pp. 245-269). London: Academic Press.
  • Cutler, A., Otake, T., & McQueen, J. M. (2009). Vowel devoicing and the perception of spoken Japanese words. Journal of the Acoustical Society of America, 125(3), 1693-1703. doi:10.1121/1.3075556.

    Abstract

    Three experiments, in which Japanese listeners detected Japanese words embedded in nonsense sequences, examined the perceptual consequences of vowel devoicing in that language. Since vowelless sequences disrupt speech segmentation [Norris et al. (1997). Cognit. Psychol. 34, 191– 243], devoicing is potentially problematic for perception. Words in initial position in nonsense sequences were detected more easily when followed by a sequence containing a vowel than by a vowelless segment (with or without further context), and vowelless segments that were potential devoicing environments were no easier than those not allowing devoicing. Thus asa, “morning,” was easier in asau or asazu than in all of asap, asapdo, asaf, or asafte, despite the fact that the /f/ in the latter two is a possible realization of fu, with devoiced [u]. Japanese listeners thus do not treat devoicing contexts as if they always contain vowels. Words in final position in nonsense sequences, however, produced a different pattern: here, preceding vowelless contexts allowing devoicing impeded word detection less strongly (so, sake was detected less accurately, but not less rapidly, in nyaksake—possibly arising from nyakusake—than in nyagusake). This is consistent with listeners treating consonant sequences as potential realizations of parts of existing lexical candidates wherever possible.
  • Cutler, A., Norris, D., & Van Ooijen, B. (1990). Vowels as phoneme detection targets. In Proceedings of the First International Conference on Spoken Language Processing (pp. 581-584).

    Abstract

    Phoneme detection is a psycholinguistic task in which listeners' response time to detect the presence of a pre-specified phoneme target is measured. Typically, detection tasks have used consonant targets. This paper reports two experiments in which subjects responded to vowels as phoneme detection targets. In the first experiment, targets occurred in real words, in the second in nonsense words. Response times were long by comparison with consonantal targets. Targets in initial syllables were responded to much more slowly than targets in second syllables. Strong vowels were responded to faster than reduced vowels in real words but not in nonwords. These results suggest that the process of phoneme detection produces different results for vowels and for consonants. We discuss possible explanations for this difference, in particular the possibility of language-specificity.
  • Dabrowska, E., Rowland, C. F., & Theakston, A. (2009). The acquisition of questions with long-distance dependencies. Cognitive Linguistics, 20(3), 571-597. doi:10.1515/COGL.2009.025.

    Abstract

    A number of researchers have claimed that questions and other constructions with long distance dependencies (LDDs) are acquired relatively early, by age 4 or even earlier, in spite of their complexity. Analysis of LDD questions in the input available to children suggests that they are extremely stereotypical, raising the possibility that children learn lexically specific templates such as WH do you think S-GAP? rather than general rules of the kind postulated in traditional linguistic accounts of this construction. We describe three elicited imitation experiments with children aged from 4;6 to 6;9 and adult controls. Participants were asked to repeat prototypical questions (i.e., questions which match the hypothesised template), unprototypical questions (which depart from it in several respects) and declarative counterparts of both types of interrogative sentences. The children performed significantly better on the prototypical variants of both constructions, even when both variants contained exactly the same lexical material, while adults showed prototypicality e¤ects for LDD questions only. These results suggest that a general declarative complementation construction emerges quite late in development (after age 6), and that even adults rely on lexically specific templates for LDD questions.
  • Dai, B., Chen, C., Long, Y., Zheng, L., Zhao, H., Bai, X., Liu, W., Zhang, Y., Liu, L., Guo, T., Ding, G., & Lu, C. (2018). Neural mechanisms for selectively tuning into the target speaker in a naturalistic noisy situation. Nature Communications, 9: 2405. doi:10.1038/s41467-018-04819-z.

    Abstract

    The neural mechanism for selectively tuning in to a target speaker while tuning out the others in a multi-speaker situation (i.e., the cocktail-party effect) remains elusive. Here we addressed this issue by measuring brain activity simultaneously from a listener and from multiple speakers while they were involved in naturalistic conversations. Results consistently show selectively enhanced interpersonal neural synchronization (INS) between the listener and the attended speaker at left temporal–parietal junction, compared with that between the listener and the unattended speaker across different multi-speaker situations. Moreover, INS increases significantly prior to the occurrence of verbal responses, and even when the listener’s brain activity precedes that of the speaker. The INS increase is independent of brain-to-speech synchronization in both the anatomical location and frequency range. These findings suggest that INS underlies the selective process in a multi-speaker situation through neural predictions at the content level but not the sensory level of speech.

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  • Davids, N. (2009). Neurocognitive markers of phonological processing: A clinical perspective. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Davids, N., Van den Brink, D., Van Turennout, M., Mitterer, H., & Verhoeven, L. (2009). Towards neurophysiological assessment of phonemic discrimination: Context effects of the mismatch negativity. Clinical Neurophysiology, 120, 1078-1086. doi:10.1016/j.clinph.2009.01.018.

    Abstract

    This study focusses on the optimal paradigm for simultaneous assessment of auditory and phonemic discrimination in clinical populations. We investigated (a) whether pitch and phonemic deviants presented together in one sequence are able to elicit mismatch negativities (MMNs) in healthy adults and (b) whether MMN elicited by a change in pitch is modulated by the presence of the phonemic deviants.
  • Davidson, D. J., & Indefrey, P. (2009). An event-related potential study on changes of violation and error responses during morphosyntactic learning. Journal of Cognitive Neuroscience, 21(3), 433-446. Retrieved from http://www.mitpressjournals.org/doi/pdf/10.1162/jocn.2008.21031.

    Abstract

    Based on recent findings showing electrophysiological changes in adult language learners after relatively short periods of training, we hypothesized that adult Dutch learners of German would show responses to German gender and adjective declension violations after brief instruction. Adjective declension in German differs from previously studied morphosyntactic regularities in that the required suffixes depend not only on the syntactic case, gender, and number features to be expressed, but also on whether or not these features are already expressed on linearly preceding elements in the noun phrase. Violation phrases and matched controls were presented over three test phases (pretest and training on the first day, and a posttest one week later). During the pretest, no electrophysiological differences were observed between violation and control conditions, and participants’ classification performance was near chance. During the training and posttest phases, classification improved, and there was a P600-like violation response to declension but not gender violations. An error-related response during training was associated with improvement in grammatical discrimination from pretest to posttest. The results show that rapid changes in neuronal responses can be observed in adult learners of a complex morphosyntactic rule, and also that error-related electrophysiological responses may relate to grammar acquisition.
  • Davidson, D. J., & Indefrey, P. (2009). Plasticity of grammatical recursion in German learners of Dutch. Language and Cognitive Processes, 24, 1335-1369. doi:10.1080/01690960902981883.

    Abstract

    Previous studies have examined cross-serial and embedded complement clauses in West Germanic in order to distinguish between different types of working memory models of human sentence processing, as well as different formal language models. Here, adult plasticity in the use of these constructions is investigated by examining the response of German-speaking learners of Dutch using magnetoencephalography (MEG). In three experimental sessions spanning their initial acquisition of Dutch, participants performed a sentence-scene matching task with Dutch sentences including two different verb constituent orders (Dutch verb order, German verb order), and in addition rated similar constructions in a separate rating task. The average planar gradient of the evoked field to the initial verb within the cluster revealed a larger evoked response for the German order relative to the Dutch order between 0.2 to 0.4 s over frontal sensors after 2 weeks, but not initially. The rating data showed that constructions consistent with Dutch grammar, but inconsistent with the German grammar were initially rated as unacceptable, but this preference reversed after 3 months. The behavioural and electrophysiological results suggest that cortical responses to verb order preferences in complement clauses can change within 3 months after the onset of adult language learning, implying that this aspect of grammatical processing remains plastic into adulthood.
  • Davies, R., Kidd, E., & Lander, K. (2009). Investigating the psycholinguistic correlates of speechreading in preschool age children. International Journal of Language & Communication Disorders, 44(2), 164-174. doi:10.1080/13682820801997189.

    Abstract

    Background: Previous research has found that newborn infants can match phonetic information in the lips and voice from as young as ten weeks old. There is evidence that access to visual speech is necessary for normal speech development. Although we have an understanding of this early sensitivity, very little research has investigated older children's ability to speechread whole words. Aims: The aim of this study was to identify aspects of preschool children's linguistic knowledge and processing ability that may contribute to speechreading ability. We predicted a significant correlation between receptive vocabulary and speechreading, as well as phonological working memory to be a predictor of speechreading performance. Methods & Procedures: Seventy-six children (n = 76) aged between 2;10 and 4;11 years participated. Children were given three pictures and were asked to point to the picture that they thought that the experimenter had silently mouthed (ten trials). Receptive vocabulary and phonological working memory were also assessed. The results were analysed using Pearson correlations and multiple regressions. Outcomes & Results: The results demonstrated that the children could speechread at a rate greater than chance. Pearson correlations revealed significant, positive correlations between receptive vocabulary and speechreading score, phonological error rate and age. Further correlations revealed significant, positive relationships between The Children's Test of Non-Word Repetition (CNRep) and speechreading score, phonological error rate and age. Multiple regression analyses showed that receptive vocabulary best predicts speechreading ability over and above phonological working memory. Conclusions & Implications: The results suggest that preschool children are capable of speechreading, and that this ability is related to vocabulary size. This suggests that children aged between 2;10 and 4;11 are sensitive to visual information in the form of audio-visual mappings. We suggest that current and future therapies are correct to include visual feedback as a therapeutic tool; however, future research needs to be conducted in order to elucidate further the role of speechreading in development.
  • Dediu, D. (2009). Genetic biasing through cultural transmission: Do simple Bayesian models of language evolution generalize? Journal of Theoretical Biology, 259, 552-561. doi:10.1016/j.jtbi.2009.04.004.

    Abstract

    The recent Bayesian approaches to language evolution and change seem to suggest that genetic biases can impact on the characteristics of language, but, at the same time, that its cultural transmission can partially free it from these same genetic constraints. One of the current debates centres on the striking differences between sampling and a posteriori maximising Bayesian learners, with the first converging on the prior bias while the latter allows a certain freedom to language evolution. The present paper shows that this difference disappears if populations more complex than a single teacher and a single learner are considered, with the resulting behaviours more similar to the sampler. This suggests that generalisations based on the language produced by Bayesian agents in such homogeneous single agent chains are not warranted. It is not clear which of the assumptions in such models are responsible, but these findings seem to support the rising concerns on the validity of the “acquisitionist” assumption, whereby the locus of language change and evolution is taken to be the first language acquirers (children) as opposed to the competent language users (the adults).
  • Dediu, D. (2018). Making genealogical language classifications available for phylogenetic analysis: Newick trees, unified identifiers, and branch length. Language Dynamics and Change, 8(1), 1-21. doi:10.1163/22105832-00801001.

    Abstract

    One of the best-known types of non-independence between languages is caused by genealogical relationships due to descent from a common ancestor. These can be represented by (more or less resolved and controversial) language family trees. In theory, one can argue that language families should be built through the strict application of the comparative method of historical linguistics, but in practice this is not always the case, and there are several proposed classifications of languages into language families, each with its own advantages and disadvantages. A major stumbling block shared by most of them is that they are relatively difficult to use with computational methods, and in particular with phylogenetics. This is due to their lack of standardization, coupled with the general non-availability of branch length information, which encapsulates the amount of evolution taking place on the family tree. In this paper I introduce a method (and its implementation in R) that converts the language classifications provided by four widely-used databases (Ethnologue, WALS, AUTOTYP and Glottolog) intothe de facto Newick standard generally used in phylogenetics, aligns the four most used conventions for unique identifiers of linguistic entities (ISO 639-3, WALS, AUTOTYP and Glottocode), and adds branch length information from a variety of sources (the tree's own topology, an externally given numeric constant, or a distance matrix). The R scripts, input data and resulting Newick trees are available under liberal open-source licenses in a GitHub repository (https://github.com/ddediu/lgfam-newick), to encourage and promote the use of phylogenetic methods to investigate linguistic diversity and its temporal dynamics.
  • Dediu, D., & Levinson, S. C. (2018). Neanderthal language revisited: Not only us. Current Opinion in Behavioral Sciences, 21, 49-55. doi:10.1016/j.cobeha.2018.01.001.

    Abstract

    Here we re-evaluate our 2013 paper on the antiquity of language (Dediu and Levinson, 2013) in the light of a surge of new information on human evolution in the last half million years. Although new genetic data suggest the existence of some cognitive differences between Neanderthals and modern humans — fully expected after hundreds of thousands of years of partially separate evolution, overall our claims that Neanderthals were fully articulate beings and that language evolution was gradual are further substantiated by the wealth of new genetic, paleontological and archeological evidence briefly reviewed here.
  • Defina, R., Allen, S. E. M., Davidson, L., Hellwig, B., Kelly, B. F., & Kidd, E. (2023). Sketch Acquisition Manual (SAM), Part I: The sketch corpus. Language Documentation and Conservation Special Publication, 28, 5-38. Retrieved from https://hdl.handle.net/10125/74719.

    Abstract

    This paper presents the first part of a guide for documenting and describing child language, child-directed language and socialization patterns in diverse languages and cultures. The guide is intended for anyone interested in working across child language and language documentation,
    including, for example, field linguists and language documenters, community language workers, child language researchers or graduate students. We assume some basic familiarity with language documentation principles and methods, and, based on this, provide step-by-step suggestions for
    collecting, analyzing and presenting child data. This first part of the guide focuses on constructing a sketch corpus that consists of minimally five hours of annotated and archived data and which documents communicative practices of children between the ages of 2 and 4.
  • Defina, R., Allen, S. E. M., Davidson, L., Hellwig, B., Kelly, B. F., & Kidd, E. (2023). Sketch Acquisition Manual (SAM), Part II: The acquisition sketch. Language Documentation and Conservation Special Publication, 28, 39-86. Retrieved from https://hdl.handle.net/10125/74720.

    Abstract

    This paper presents the second part of a guide for documenting and describing child language, child-directed language and socialization patterns in diverse languages and cultures. The guide is intended for anyone interested in working across child language and language documentation,
    including, for example, field linguists and language documenters, community language workers, child language researchers or graduate students. We assume some basic familiarity with language documentation principles and methods, and, based on this, provide step-by-step suggestions for
    collecting, analyzing and presenting child data. This second part of the guide focuses on developing a child language acquisition sketch. It takes the sketch corpus as its basis (which was introduced in the first part of this guide), and presents a model for analyzing and describing the corpus data.
  • Degand, L., & Van Bergen, G. (2018). Discourse markers as turn-transition devices: Evidence from speech and instant messaging. Discourse Processes, 55, 47-71. doi:10.1080/0163853X.2016.1198136.

    Abstract

    In this article we investigate the relation between discourse markers and turn-transition strategies in face-to-face conversations and Instant Messaging (IM), that is, unplanned, real-time, text-based, computer-mediated communication. By means of a quantitative corpus study of utterances containing a discourse marker, we show that utterance-final discourse markers are used more often in IM than in face-to-face conversations. Moreover, utterance-final discourse markers are shown to occur more often at points of turn-transition compared with points of turn-maintenance in both types of conversation. From our results we conclude that the discourse markers in utterance-final position can function as a turn-transition mechanism, signaling that the turn is over and the floor is open to the hearer. We argue that this linguistic turn-taking strategy is essentially similar in face-to-face and IM communication. Our results add to the evidence that communication in IM is more like speech than like writing.
  • Delgado, T., Ravignani, A., Verhoef, T., Thompson, B., Grossi, T., & Kirby, S. (2018). Cultural transmission of melodic and rhythmic universals: Four experiments and a model. In C. Cuskley, M. Flaherty, H. Little, L. McCrohon, A. Ravignani, & T. Verhoef (Eds.), Proceedings of the 12th International Conference on the Evolution of Language (EVOLANG XII) (pp. 89-91). Toruń, Poland: NCU Press. doi:10.12775/3991-1.019.
  • Den Hoed, J., Sollis, E., Venselaar, H., Estruch, S. B., Derizioti, P., & Fisher, S. E. (2018). Functional characterization of TBR1 variants in neurodevelopmental disorder. Scientific Reports, 8: 14279. doi:10.1038/s41598-018-32053-6.

    Abstract

    Recurrent de novo variants in the TBR1 transcription factor are implicated in the etiology of sporadic autism spectrum disorders (ASD). Disruptions include missense variants located in the T-box DNA-binding domain and previous work has demonstrated that they disrupt TBR1 protein function. Recent screens of thousands of simplex families with sporadic ASD cases uncovered additional T-box variants in TBR1 but their etiological relevance is unclear. We performed detailed functional analyses of de novo missense TBR1 variants found in the T-box of ASD cases, assessing many aspects of protein function, including subcellular localization, transcriptional activity and protein-interactions. Only two of the three tested variants severely disrupted TBR1 protein function, despite in silico predictions that all would be deleterious. Furthermore, we characterized a putative interaction with BCL11A, a transcription factor that was recently implicated in a neurodevelopmental syndrome involving developmental delay and language deficits. Our findings enhance understanding of molecular functions of TBR1, as well as highlighting the importance of functional testing of variants that emerge from next-generation sequencing, to decipher their contributions to neurodevelopmental disorders like ASD.

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  • Devanna, P., Van de Vorst, M., Pfundt, R., Gilissen, C., & Vernes, S. C. (2018). Genome-wide investigation of an ID cohort reveals de novo 3′UTR variants affecting gene expression. Human Genetics, 137(9), 717-721. doi:10.1007/s00439-018-1925-9.

    Abstract

    Intellectual disability (ID) is a severe neurodevelopmental disorder with genetically heterogeneous causes. Large-scale sequencing has led to the identification of many gene-disrupting mutations; however, a substantial proportion of cases lack a molecular diagnosis. As such, there remains much to uncover for a complete understanding of the genetic underpinnings of ID. Genetic variants present in non-coding regions of the genome have been highlighted as potential contributors to neurodevelopmental disorders given their role in regulating gene expression. Nevertheless the functional characterization of non-coding variants remains challenging. We describe the identification and characterization of de novo non-coding variation in 3′UTR regulatory regions within an ID cohort of 50 patients. This cohort was previously screened for structural and coding pathogenic variants via CNV, whole exome and whole genome analysis. We identified 44 high-confidence single nucleotide non-coding variants within the 3′UTR regions of these 50 genomes. Four of these variants were located within predicted miRNA binding sites and were thus hypothesised to have regulatory consequences. Functional testing showed that two of the variants interfered with miRNA-mediated regulation of their target genes, AMD1 and FAIM. Both these variants were found in the same individual and their functional consequences may point to a potential role for such variants in intellectual disability.

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  • Devanna, P., Chen, X. S., Ho, J., Gajewski, D., Smith, S. D., Gialluisi, A., Francks, C., Fisher, S. E., Newbury, D. F., & Vernes, S. C. (2018). Next-gen sequencing identifies non-coding variation disrupting miRNA binding sites in neurological disorders. Molecular Psychiatry, 23(5), 1375-1384. doi:10.1038/mp.2017.30.

    Abstract

    Understanding the genetic factors underlying neurodevelopmental and neuropsychiatric disorders is a major challenge given their prevalence and potential severity for quality of life. While large-scale genomic screens have made major advances in this area, for many disorders the genetic underpinnings are complex and poorly understood. To date the field has focused predominantly on protein coding variation, but given the importance of tightly controlled gene expression for normal brain development and disorder, variation that affects non-coding regulatory regions of the genome is likely to play an important role in these phenotypes. Herein we show the importance of 3 prime untranslated region (3'UTR) non-coding regulatory variants across neurodevelopmental and neuropsychiatric disorders. We devised a pipeline for identifying and functionally validating putatively pathogenic variants from next generation sequencing (NGS) data. We applied this pipeline to a cohort of children with severe specific language impairment (SLI) and identified a functional, SLI-associated variant affecting gene regulation in cells and post-mortem human brain. This variant and the affected gene (ARHGEF39) represent new putative risk factors for SLI. Furthermore, we identified 3′UTR regulatory variants across autism, schizophrenia and bipolar disorder NGS cohorts demonstrating their impact on neurodevelopmental and neuropsychiatric disorders. Our findings show the importance of investigating non-coding regulatory variants when determining risk factors contributing to neurodevelopmental and neuropsychiatric disorders. In the future, integration of such regulatory variation with protein coding changes will be essential for uncovering the genetic causes of complex neurological disorders and the fundamental mechanisms underlying health and disease

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    mp201730x1.docx
  • Dideriksen, C., Christiansen, M. H., Tylén, K., Dingemanse, M., & Fusaroli, R. (2023). Quantifying the interplay of conversational devices in building mutual understanding. Journal of Experimental Psychology: General, 152(3), 864-889. doi:10.1037/xge0001301.

    Abstract

    Humans readily engage in idle chat and heated discussions and negotiate tough joint decisions without ever having to think twice about how to keep the conversation grounded in mutual understanding. However, current attempts at identifying and assessing the conversational devices that make this possible are fragmented across disciplines and investigate single devices within single contexts. We present a comprehensive conceptual framework to investigate conversational devices, their relations, and how they adjust to contextual demands. In two corpus studies, we systematically test the role of three conversational devices: backchannels, repair, and linguistic entrainment. Contrasting affiliative and task-oriented conversations within participants, we find that conversational devices adaptively adjust to the increased need for precision in the latter: We show that low-precision devices such as backchannels are more frequent in affiliative conversations, whereas more costly but higher-precision mechanisms, such as specific repairs, are more frequent in task-oriented conversations. Further, task-oriented conversations involve higher complementarity of contributions in terms of the content and perspective: lower semantic entrainment and less frequent (but richer) lexical and syntactic entrainment. Finally, we show that the observed variations in the use of conversational devices are potentially adaptive: pairs of interlocutors that show stronger linguistic complementarity perform better across the two tasks. By combining motivated comparisons of several conversational contexts and theoretically informed computational analyses of empirical data the present work lays the foundations for a comprehensive conceptual framework for understanding the use of conversational devices in dialogue.
  • Dideriksen, C., Christiansen, M. H., Dingemanse, M., Højmark‐Bertelsen, M., Johansson, C., Tylén, K., & Fusaroli, R. (2023). Language‐specific constraints on conversation: Evidence from Danish and Norwegian. Cognitive Science, 47(11): e13387. doi:10.1111/cogs.13387.

    Abstract

    Establishing and maintaining mutual understanding in everyday conversations is crucial. To do so, people employ a variety of conversational devices, such as backchannels, repair, and linguistic entrainment. Here, we explore whether the use of conversational devices might be influenced by cross-linguistic differences in the speakers’ native language, comparing two matched languages—Danish and Norwegian—differing primarily in their sound structure, with Danish being more opaque, that is, less acoustically distinguished. Across systematically manipulated conversational contexts, we find that processes supporting mutual understanding in conversations vary with external constraints: across different contexts and, crucially, across languages. In accord with our predictions, linguistic entrainment was overall higher in Danish than in Norwegian, while backchannels and repairs presented a more nuanced pattern. These findings are compatible with the hypothesis that native speakers of Danish may compensate for its opaque sound structure by adopting a top-down strategy of building more conversational redundancy through entrainment, which also might reduce the need for repairs. These results suggest that linguistic differences might be met by systematic changes in language processing and use. This paves the way for further cross-linguistic investigations and critical assessment of the interplay between cultural and linguistic factors on the one hand and conversational dynamics on the other.
  • Dikshit, A. P., Mishra, C., Das, D., & Parashar, S. (2023). Frequency and temperature-dependence ZnO based fractional order capacitor using machine learning. Materials Chemistry and Physics, 307: 128097. doi:10.1016/j.matchemphys.2023.128097.

    Abstract

    This paper investigates the fractional order behavior of ZnO ceramics at different frequencies. ZnO ceramic was prepared by high energy ball milling technique (HEBM) sintered at 1300℃ to study the frequency response properties. The frequency response properties (impedance and phase
    angles) were examined by analyzing through impedance analyzer (100 Hz - 1 MHz). Constant phase angles (84°-88°) were obtained at low temperature ranges (25 ℃-125 ℃). The structural and
    morphological composition of the ZnO ceramic was investigated using X-ray diffraction techniques and FESEM. Raman spectrum was studied to understand the different modes of ZnO ceramics. Machine learning (polynomial regression) models were trained on a dataset of 1280
    experimental values to accurately predict the relationship between frequency and temperature with respect to impedance and phase values of the ZnO ceramic FOC. The predicted impedance values were found to be in good agreement (R2 ~ 0.98, MSE ~ 0.0711) with the experimental results.
    Impedance values were also predicted beyond the experimental frequency range (at 50 Hz and 2 MHz) for different temperatures (25℃ - 500℃) and for low temperatures (10°, 15° and 20℃)
    within the frequency range (100Hz - 1MHz).

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  • Dimitrova, D. V., Redeker, G., & Hoeks, J. C. J. (2009). Did you say a BLUE banana? The prosody of contrast and abnormality in Bulgarian and Dutch. In 10th Annual Conference of the International Speech Communication Association [Interspeech 2009] (pp. 999-1002). ISCA Archive.

    Abstract

    In a production experiment on Bulgarian that was based on a previous study on Dutch [1], we investigated the role of prosody when linguistic and extra-linguistic information coincide or contradict. Speakers described abnormally colored fruits in conditions where contrastive focus and discourse relations were varied. We found that the coincidence of contrast and abnormality enhances accentuation in Bulgarian as it did in Dutch. Surprisingly, when both factors are in conflict, the prosodic prominence of abnormality often overruled focus accentuation in both Bulgarian and Dutch, though the languages also show marked differences.
  • Dimroth, C., & Narasimhan, B. (2009). Accessibility and topicality in children's use of word order. In J. Chandlee, M. Franchini, S. Lord, & G. M. Rheiner (Eds.), Proceedings of the 33rd annual Boston University Conference on Language Development (BULCD) (pp. 133-138).
  • Dimroth, C., & Klein, W. (2009). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik, 153, 5-9.
  • Dimroth, C., & Jordens, P. (Eds.). (2009). Functional categories in learner language. Berlin: Mouton de Gruyter.
  • Dimroth, C. (2009). L'acquisition de la finitude en allemand L2 à différents âges. AILE (Acquisition et Interaction en Langue étrangère)/LIA (Languages, Interaction, Acquisition), 1(1), 113-135.

    Abstract

    Ultimate attainment in adult second language learners often differs tremendously from the end state typically achieved by young children learning their first language (L1) or a second language (L2). The research summarized in this article concentrates on developmental steps and orders of acquisition attested in learners of different ages. Findings from a longitudinal study concerned with the acquisition of verbal morpho-syntax in German as an L2 by two young Russian learners (8 and 14 years old) are compared to findings from the acquisition of the same target language by younger children and by untutored adult learners. The study focuses on the acquisition of verbal morphology, the role of auxiliary verbs and the position of finite and non finite verbs in relation to negation and additive scope particles.
  • Dimroth, C. (2009). Lernervarietäten im Sprachunterricht. Zeitschrift für Literaturwissenschaft und Linguistik, 39(153), 60-80.
  • Dimroth, C. (2009). Stepping stones and stumbling blocks: Why negation accelerates and additive particles delay the acquisition of finiteness in German. In C. Dimroth, & P. Jordens (Eds.), Functional Categories in Learner Language (pp. 137-170). Berlin: Mouton de Gruyter.
  • Dingemans, A. J. M., Hinne, M., Truijen, K. M. G., Goltstein, L., Van Reeuwijk, J., De Leeuw, N., Schuurs-Hoeijmakers, J., Pfundt, R., Diets, I. J., Den Hoed, J., De Boer, E., Coenen-Van der Spek, J., Jansen, S., Van Bon, B. W., Jonis, N., Ockeloen, C. W., Vulto-van Silfhout, A. T., Kleefstra, T., Koolen, D. A., Campeau, P. M. and 13 moreDingemans, A. J. M., Hinne, M., Truijen, K. M. G., Goltstein, L., Van Reeuwijk, J., De Leeuw, N., Schuurs-Hoeijmakers, J., Pfundt, R., Diets, I. J., Den Hoed, J., De Boer, E., Coenen-Van der Spek, J., Jansen, S., Van Bon, B. W., Jonis, N., Ockeloen, C. W., Vulto-van Silfhout, A. T., Kleefstra, T., Koolen, D. A., Campeau, P. M., Palmer, E. E., Van Esch, H., Lyon, G. J., Alkuraya, F. S., Rauch, A., Marom, R., Baralle, D., Van der Sluijs, P. J., Santen, G. W. E., Kooy, R. F., Van Gerven, M. A. J., Vissers, L. E. L. M., & De Vries, B. B. A. (2023). PhenoScore quantifies phenotypic variation for rare genetic diseases by combining facial analysis with other clinical features using a machine-learning framework. Nature Genetics, 55, 1598-1607. doi:10.1038/s41588-023-01469-w.

    Abstract

    Several molecular and phenotypic algorithms exist that establish genotype–phenotype correlations, including facial recognition tools. However, no unified framework that investigates both facial data and other phenotypic data directly from individuals exists. We developed PhenoScore: an open-source, artificial intelligence-based phenomics framework, combining facial recognition technology with Human Phenotype Ontology data analysis to quantify phenotypic similarity. Here we show PhenoScore’s ability to recognize distinct phenotypic entities by establishing recognizable phenotypes for 37 of 40 investigated syndromes against clinical features observed in individuals with other neurodevelopmental disorders and show it is an improvement on existing approaches. PhenoScore provides predictions for individuals with variants of unknown significance and enables sophisticated genotype–phenotype studies by testing hypotheses on possible phenotypic (sub)groups. PhenoScore confirmed previously known phenotypic subgroups caused by variants in the same gene for SATB1, SETBP1 and DEAF1 and provides objective clinical evidence for two distinct ADNP-related phenotypes, already established functionally.

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  • Dingemanse, M., Liesenfeld, A., Rasenberg, M., Albert, S., Ameka, F. K., Birhane, A., Bolis, D., Cassell, J., Clift, R., Cuffari, E., De Jaegher, H., Dutilh Novaes, C., Enfield, N. J., Fusaroli, R., Gregoromichelaki, E., Hutchins, E., Konvalinka, I., Milton, D., Rączaszek-Leonardi, J., Reddy, V. and 8 moreDingemanse, M., Liesenfeld, A., Rasenberg, M., Albert, S., Ameka, F. K., Birhane, A., Bolis, D., Cassell, J., Clift, R., Cuffari, E., De Jaegher, H., Dutilh Novaes, C., Enfield, N. J., Fusaroli, R., Gregoromichelaki, E., Hutchins, E., Konvalinka, I., Milton, D., Rączaszek-Leonardi, J., Reddy, V., Rossano, F., Schlangen, D., Seibt, J., Stokoe, E., Suchman, L. A., Vesper, C., Wheatley, T., & Wiltschko, M. (2023). Beyond single-mindedness: A figure-ground reversal for the cognitive sciences. Cognitive Science, 47(1): e13230. doi:10.1111/cogs.13230.

    Abstract

    A fundamental fact about human minds is that they are never truly alone: all minds are steeped in situated interaction. That social interaction matters is recognised by any experimentalist who seeks to exclude its influence by studying individuals in isolation. On this view, interaction complicates cognition. Here we explore the more radical stance that interaction co-constitutes cognition: that we benefit from looking beyond single minds towards cognition as a process involving interacting minds. All around the cognitive sciences, there are approaches that put interaction centre stage. Their diverse and pluralistic origins may obscure the fact that collectively, they harbour insights and methods that can respecify foundational assumptions and fuel novel interdisciplinary work. What might the cognitive sciences gain from stronger interactional foundations? This represents, we believe, one of the key questions for the future. Writing as a multidisciplinary collective assembled from across the classic cognitive science hexagon and beyond, we highlight the opportunity for a figure-ground reversal that puts interaction at the heart of cognition. The interactive stance is a way of seeing that deserves to be a key part of the conceptual toolkit of cognitive scientists.
  • Dingemanse, M. (2009). Kããã [finalist photo in the 2008 AAA Photo Contest]. Anthropology News, 50(3), 23-23.

    Abstract

    Kyeei Yao, an age group leader, oversees a festival in Akpafu-Mempeasem, Volta Region, Ghana. The expensive draped cloth, Ashanti-inspired wreath, strings of beads that are handed down through the generations, and digital wristwatch work together to remind us that culture is a moving target, always renewing and reshaping itself. Kããã is a Siwu ideophone for "looking attentively".
  • Dingemanse, M., Blythe, J., & Dirksmeyer, T. (2018). Formats for other-initiation of repair across languages: An exercise in pragmatic typology. In I. Nikolaeva (Ed.), Linguistic Typology: Critical Concepts in Linguistics. Vol. 4 (pp. 322-357). London: Routledge.

    Abstract

    In conversation, people regularly deal with problems of speaking, hearing, and understanding. We report on a cross-linguistic investigation of the conversational structure of other-initiated repair (also known as collaborative repair, feedback, requests for clarification, or grounding sequences). We take stock of formats for initiating repair across languages (comparable to English huh?, who?, y’mean X?, etc.) and find that different languages make available a wide but remarkably similar range of linguistic resources for this function. We exploit the patterned variation as evidence for several underlying concerns addressed by repair initiation: characterising trouble, managing responsibility, and handling knowledge. The concerns do not always point in the same direction and thus provide participants in interaction with alternative principles for selecting one format over possible others. By comparing conversational structures across languages, this paper contributes to pragmatic typology: the typology of systems of language use and the principles that shape them.
  • Dingemanse, M. (2009). Ideophones in unexpected places. In P. K. Austin, O. Bond, M. Charette, D. Nathan, & P. Sells (Eds.), Proceedings of the 2nd Conference on Language Documentation and Linguistic Theory (pp. 83-97). London: School of Oriental and African Studies (SOAS).
  • Dingemanse, M. (2018). Redrawing the margins of language: Lessons from research on ideophones. Glossa: a journal of general linguistics, 3(1): 4. doi:10.5334/gjgl.444.

    Abstract

    Ideophones (also known as expressives or mimetics, and including onomatopoeia) have been systematically studied in linguistics since the 1850s, when they were first described as a lexical class of vivid sensory words in West-African languages. This paper surveys the research history of ideophones, from its roots in African linguistics to its fruits in general linguistics and typology around the globe. It shows that despite a recurrent narrative of marginalisation, work on ideophones has made an impact in many areas of linguistics, from theories of phonological features to typologies of manner and motion, and from sound symbolism to sensory language. Due to their hybrid nature as gradient vocal gestures that grow roots in discrete linguistic systems, ideophones provide opportunities to reframe typological questions, reconsider the role of language ideology in linguistic scholarship, and rethink the margins of language. With ideophones increasingly being brought into the fold of the language sciences, this review synthesises past theoretical insights and empirical findings in order to enable future work to build on them.

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