Publications

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  • Bosker, H. R., Reinisch, E., & Sjerps, M. J. (2017). Cognitive load makes speech sound fast, but does not modulate acoustic context effects. Journal of Memory and Language, 94, 166-176. doi:10.1016/j.jml.2016.12.002.

    Abstract

    In natural situations, speech perception often takes place during the concurrent execution of other cognitive tasks, such as listening while viewing a visual scene. The execution of a dual task typically has detrimental effects on concurrent speech perception, but how exactly cognitive load disrupts speech encoding is still unclear. The detrimental effect on speech representations may consist of either a general reduction in the robustness of processing of the speech signal (‘noisy encoding’), or, alternatively it may specifically influence the temporal sampling of the sensory input, with listeners missing temporal pulses, thus underestimating segmental durations (‘shrinking of time’). The present study investigated whether and how spectral and temporal cues in a precursor sentence that has been processed under high vs. low cognitive load influence the perception of a subsequent target word. If cognitive load effects are implemented through ‘noisy encoding’, increasing cognitive load during the precursor should attenuate the encoding of both its temporal and spectral cues, and hence reduce the contextual effect that these cues can have on subsequent target sound perception. However, if cognitive load effects are expressed as ‘shrinking of time’, context effects should not be modulated by load, but a main effect would be expected on the perceived duration of the speech signal. Results from two experiments indicate that increasing cognitive load (manipulated through a secondary visual search task) did not modulate temporal (Experiment 1) or spectral context effects (Experiment 2). However, a consistent main effect of cognitive load was found: increasing cognitive load during the precursor induced a perceptual increase in its perceived speech rate, biasing the perception of a following target word towards longer durations. This finding suggests that cognitive load effects in speech perception are implemented via ‘shrinking of time’, in line with a temporal sampling framework. In addition, we argue that our results align with a model in which early (spectral and temporal) normalization is unaffected by attention but later adjustments may be attention-dependent.
  • Bosker, H. R., & Kösem, A. (2017). An entrained rhythm's frequency, not phase, influences temporal sampling of speech. In Proceedings of Interspeech 2017 (pp. 2416-2420). doi:10.21437/Interspeech.2017-73.

    Abstract

    Brain oscillations have been shown to track the slow amplitude fluctuations in speech during comprehension. Moreover, there is evidence that these stimulus-induced cortical rhythms may persist even after the driving stimulus has ceased. However, how exactly this neural entrainment shapes speech perception remains debated. This behavioral study investigated whether and how the frequency and phase of an entrained rhythm would influence the temporal sampling of subsequent speech. In two behavioral experiments, participants were presented with slow and fast isochronous tone sequences, followed by Dutch target words ambiguous between as /ɑs/ “ash” (with a short vowel) and aas /a:s/ “bait” (with a long vowel). Target words were presented at various phases of the entrained rhythm. Both experiments revealed effects of the frequency of the tone sequence on target word perception: fast sequences biased listeners to more long /a:s/ responses. However, no evidence for phase effects could be discerned. These findings show that an entrained rhythm’s frequency, but not phase, influences the temporal sampling of subsequent speech. These outcomes are compatible with theories suggesting that sensory timing is evaluated relative to entrained frequency. Furthermore, they suggest that phase tracking of (syllabic) rhythms by theta oscillations plays a limited role in speech parsing.
  • Bosker, H. R., & Reinisch, E. (2017). Foreign languages sound fast: evidence from implicit rate normalization. Frontiers in Psychology, 8: 1063. doi:10.3389/fpsyg.2017.01063.

    Abstract

    Anecdotal evidence suggests that unfamiliar languages sound faster than one’s native language. Empirical evidence for this impression has, so far, come from explicit rate judgments. The aim of the present study was to test whether such perceived rate differences between native and foreign languages have effects on implicit speech processing. Our measure of implicit rate perception was “normalization for speaking rate”: an ambiguous vowel between short /a/ and long /a:/ is interpreted as /a:/ following a fast but as /a/ following a slow carrier sentence. That is, listeners did not judge speech rate itself; instead, they categorized ambiguous vowels whose perception was implicitly affected by the rate of the context. We asked whether a bias towards long /a:/ might be observed when the context is not actually faster but simply spoken in a foreign language. A fully symmetrical experimental design was used: Dutch and German participants listened to rate matched (fast and slow) sentences in both languages spoken by the same bilingual speaker. Sentences were followed by nonwords that contained vowels from an /a-a:/ duration continuum. Results from Experiments 1 and 2 showed a consistent effect of rate normalization for both listener groups. Moreover, for German listeners, across the two experiments, foreign sentences triggered more /a:/ responses than (rate matched) native sentences, suggesting that foreign sentences were indeed perceived as faster. Moreover, this Foreign Language effect was modulated by participants’ ability to understand the foreign language: those participants that scored higher on a foreign language translation task showed less of a Foreign Language effect. However, opposite effects were found for the Dutch listeners. For them, their native rather than the foreign language induced more /a:/ responses. Nevertheless, this reversed effect could be reduced when additional spectral properties of the context were controlled for. Experiment 3, using explicit rate judgments, replicated the effect for German but not Dutch listeners. We therefore conclude that the subjective impression that foreign languages sound fast may have an effect on implicit speech processing, with implications for how language learners perceive spoken segments in a foreign language.

    Additional information

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  • Bosker, H. R. (2017). How our own speech rate influences our perception of others. Journal of Experimental Psychology: Learning, Memory, and Cognition, 43(8), 1225-1238. doi:10.1037/xlm0000381.

    Abstract

    In conversation, our own speech and that of others follow each other in rapid succession. Effects of the surrounding context on speech perception are well documented but, despite the ubiquity of the sound of our own voice, it is unknown whether our own speech also influences our perception of other talkers. This study investigated context effects induced by our own speech through six experiments, specifically targeting rate normalization (i.e., perceiving phonetic segments relative to surrounding speech rate). Experiment 1 revealed that hearing pre-recorded fast or slow context sentences altered the perception of ambiguous vowels, replicating earlier work. Experiment 2 demonstrated that talking at a fast or slow rate prior to target presentation also altered target perception, though the effect of preceding speech rate was reduced. Experiment 3 showed that silent talking (i.e., inner speech) at fast or slow rates did not modulate the perception of others, suggesting that the effect of self-produced speech rate in Experiment 2 arose through monitoring of the external speech signal. Experiment 4 demonstrated that, when participants were played back their own (fast/slow) speech, no reduction of the effect of preceding speech rate was observed, suggesting that the additional task of speech production may be responsible for the reduced effect in Experiment 2. Finally, Experiments 5 and 6 replicate Experiments 2 and 3 with new participant samples. Taken together, these results suggest that variation in speech production may induce variation in speech perception, thus carrying implications for our understanding of spoken communication in dialogue settings.
  • Bosker, H. R. (2013). Juncture (prosodic). In G. Khan (Ed.), Encyclopedia of Hebrew Language and Linguistics (pp. 432-434). Leiden: Brill.

    Abstract

    Prosodic juncture concerns the compartmentalization and partitioning of syntactic entities in spoken discourse by means of prosody. It has been argued that the Intonation Unit, defined by internal criteria and prosodic boundary phenomena (e.g., final lengthening, pitch reset, pauses), encapsulates the basic structural unit of spoken Modern Hebrew.
  • Bosker, H. R., & Reinisch, E. (2015). Normalization for speechrate in native and nonnative speech. In M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congresses of Phonetic Sciences (ICPhS 2015). London: International Phonetic Association.

    Abstract

    Speech perception involves a number of processes that deal with variation in the speech signal. One such process is normalization for speechrate: local temporal cues are perceived relative to the rate in the surrounding context. It is as yet unclear whether and how this perceptual effect interacts with higher level impressions of rate, such as a speaker’s nonnative identity. Nonnative speakers typically speak more slowly than natives, an experience that listeners take into account when explicitly judging the rate of nonnative speech. The present study investigated whether this is also reflected in implicit rate normalization. Results indicate that nonnative speech is implicitly perceived as faster than temporally-matched native speech, suggesting that the additional cognitive load of listening to an accent speeds up rate perception. Therefore, rate perception in speech is not dependent on syllable durations alone but also on the ease of processing of the temporal signal.
  • Bosker, H. R. (2013). Sibilant consonants. In G. Khan (Ed.), Encyclopedia of Hebrew Language and Linguistics (pp. 557-561). Leiden: Brill.

    Abstract

    Fricative consonants in Hebrew can be divided into bgdkpt and sibilants (ז, ס, צ, שׁ, שׂ). Hebrew sibilants have been argued to stem from Proto-Semitic affricates, laterals, interdentals and /s/. In standard Israeli Hebrew the sibilants are pronounced as [s] (ס and שׂ), [ʃ] (שׁ), [z] (ז), [ʦ] (צ).
  • Bosker, H. R. (2017). The role of temporal amplitude modulations in the political arena: Hillary Clinton vs. Donald Trump. In Proceedings of Interspeech 2017 (pp. 2228-2232). doi:10.21437/Interspeech.2017-142.

    Abstract

    Speech is an acoustic signal with inherent amplitude modulations in the 1-9 Hz range. Recent models of speech perception propose that this rhythmic nature of speech is central to speech recognition. Moreover, rhythmic amplitude modulations have been shown to have beneficial effects on language processing and the subjective impression listeners have of the speaker. This study investigated the role of amplitude modulations in the political arena by comparing the speech produced by Hillary Clinton and Donald Trump in the three presidential debates of 2016. Inspection of the modulation spectra, revealing the spectral content of the two speakers’ amplitude envelopes after matching for overall intensity, showed considerably greater power in Clinton’s modulation spectra (compared to Trump’s) across the three debates, particularly in the 1-9 Hz range. The findings suggest that Clinton’s speech had a more pronounced temporal envelope with rhythmic amplitude modulations below 9 Hz, with a preference for modulations around 3 Hz. This may be taken as evidence for a more structured temporal organization of syllables in Clinton’s speech, potentially due to more frequent use of preplanned utterances. Outcomes are interpreted in light of the potential beneficial effects of a rhythmic temporal envelope on intelligibility and speaker perception.
  • Bosker, H. R., Pinget, A.-F., Quené, H., Sanders, T., & De Jong, N. H. (2013). What makes speech sound fluent? The contributions of pauses, speed and repairs. Language testing, 30(2), 159-175. doi:10.1177/0265532212455394.

    Abstract

    The oral fluency level of an L2 speaker is often used as a measure in assessing language proficiency. The present study reports on four experiments investigating the contributions of three fluency aspects (pauses, speed and repairs) to perceived fluency. In Experiment 1 untrained raters evaluated the oral fluency of L2 Dutch speakers. Using specific acoustic measures of pause, speed and repair phenomena, linear regression analyses revealed that pause and speed measures best predicted the subjective fluency ratings, and that repair measures contributed only very little. A second research question sought to account for these results by investigating perceptual sensitivity to acoustic pause, speed and repair phenomena, possibly accounting for the results from Experiment 1. In Experiments 2–4 three new groups of untrained raters rated the same L2 speech materials from Experiment 1 on the use of pauses, speed and repairs. A comparison of the results from perceptual sensitivity (Experiments 2–4) with fluency perception (Experiment 1) showed that perceptual sensitivity alone could not account for the contributions of the three aspects to perceived fluency. We conclude that listeners weigh the importance of the perceived aspects of fluency to come to an overall judgment.
  • Bosking, W. H., Sun, P., Ozker, M., Pei, X., Foster, B. L., Beauchamp, M. S., & Yoshor, D. (2017). Saturation in phosphene size with increasing current levels delivered to human visual cortex. The Journal of Neuroscience, 37(30), 7188-7197. doi:10.1523/JNEUROSCI.2896-16.2017.

    Abstract

    Electrically stimulating early visual cortex results in a visual percept known as a phosphene. Although phosphenes can be evoked by a wide range of electrode sizes and current amplitudes, they are invariably described as small. To better understand this observation, we electrically stimulated 93 electrodes implanted in the visual cortex of 13 human subjects who reported phosphene size while stimulation current was varied. Phosphene size increased as the stimulation current was initially raised above threshold, but then rapidly reached saturation. Phosphene size also depended on the location of the stimulated site, with size increasing with distance from the foveal representation. We developed a model relating phosphene size to the amount of activated cortex and its location within the retinotopic map. First, a sigmoidal curve was used to predict the amount of activated cortex at a given current. Second, the amount of active cortex was converted to degrees of visual angle by multiplying by the inverse cortical magnification factor for that retinotopic location. This simple model accurately predicted phosphene size for a broad range of stimulation currents and cortical locations. The unexpected saturation in phosphene sizes suggests that the functional architecture of cerebral cortex may impose fundamental restrictions on the spread of artificially evoked activity and this may be an important consideration in the design of cortical prosthetic devices.
  • Bosman, A., Moisik, S. R., Dediu, D., & Waters-Rist, A. (2017). Talking heads: Morphological variation in the human mandible over the last 500 years in the Netherlands. HOMO - Journal of Comparative Human Biology, 68(5), 329-342. doi:10.1016/j.jchb.2017.08.002.

    Abstract

    The primary aim of this paper is to assess patterns of morphological variation in the mandible to investigate changes during the last 500 years in the Netherlands. Three-dimensional geometric morphometrics is used on data collected from adults from three populations living in the Netherlands during three time-periods. Two of these samples come from Dutch archaeological sites (Alkmaar, 1484-1574, n = 37; and Middenbeemster, 1829-1866, n = 51) and were digitized using a 3D laser scanner. The third is a modern sample obtained from MRI scans of 34 modern Dutch individuals. Differences between mandibles are dominated by size. Significant differences in size are found among samples, with on average, males from Alkmaar having the largest mandibles and females from Middenbeemster having the smallest. The results are possibly linked to a softening of the diet, due to a combination of differences in food types and food processing that occurred between these time-periods. Differences in shape are most noticeable between males from Alkmaar and Middenbeemster. Shape differences between males and females are concentrated in the symphysis and ramus, which is mostly the consequence of sexual dimorphism. The relevance of this research is a better understanding of the anatomical variation of the mandible that can occur over an evolutionarily short time, as well as supporting research that has shown plasticity of the mandibular form related to diet and food processing. This plasticity of form must be taken into account in phylogenetic research and when the mandible is used in sex estimation of skeletons.
  • Bouhali, F., Mongelli, V., & Cohen, L. (2017). Musical literacy shifts asymmetries in the ventral visual cortex. NeuroImage, 156, 445-455. doi:10.1016/j.neuroimage.2017.04.027.

    Abstract

    The acquisition of literacy has a profound impact on the functional specialization and lateralization of the visual cortex. Due to the overall lateralization of the language network, specialization for printed words develops in the left occipitotemporal cortex, allegedly inducing a secondary shift of visual face processing to the right, in literate as compared to illiterate subjects. Applying the same logic to the acquisition of high-level musical literacy, we predicted that, in musicians as compared to non-musicians, occipitotemporal activations should show a leftward shift for music reading, and an additional rightward push for face perception. To test these predictions, professional musicians and non-musicians viewed pictures of musical notation, faces, words, tools and houses in the MRI, and laterality was assessed in the ventral stream combining ROI and voxel-based approaches. The results supported both predictions, and allowed to locate the leftward shift to the inferior temporal gyrus and the rightward shift to the fusiform cortex. Moreover, these laterality shifts generalized to categories other than music and faces. Finally, correlation measures across subjects did not support a causal link between the leftward and rightward shifts. Thus the acquisition of an additional perceptual expertise extensively modifies the laterality pattern in the visual system

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    1-s2.0-S1053811917303208-mmc1.docx

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  • Bowerman, M. (1996). Argument structure and learnability: Is a solution in sight? In J. Johnson, M. L. Juge, & J. L. Moxley (Eds.), Proceedings of the Twenty-second Annual Meeting of the Berkeley Linguistics Society, February 16-19, 1996. General Session and Parasession on The Role of Learnability in Grammatical Theory (pp. 454-468). Berkeley Linguistics Society.
  • Bowerman, M. (1996). Learning how to structure space for language: A crosslinguistic perspective. In P. Bloom, M. A. Peterson, L. Nadel, & M. F. Garrett (Eds.), Language and space (pp. 385-436). Cambridge, MA: MIT press.
  • Bowerman, M. (1977). The acquisition of rules governing ‘possible lexical items’: Evidence from spontaneous speech errors. Papers and Reports on Child Language Development, 13, 148-156.
  • Bowerman, M. (1977). The acquisition of word meaning: An investigation of some current concepts. In P. Johnson Laird, & P. Wason (Eds.), Thinking: Readings in cognitive science (pp. 239-253). Cambridge: Cambridge University Press.
  • Bowerman, M. (1996). The origins of children's spatial semantic categories: Cognitive vs. linguistic determinants. In J. J. Gumperz, & S. C. Levinson (Eds.), Rethinking linguistic relativity (pp. 145-176). Cambridge University Press.
  • Bowerman, M. (1980). The structure and origin of semantic categories in the language learning child. In M. Foster, & S. Brandes (Eds.), Symbol as sense (pp. 277-299). New York: Academic Press.
  • Boyle, W., Lindell, A. K., & Kidd, E. (2013). Investigating the role of verbal working memory in young children's sentence comprehension. Language Learning, 63(2), 211-242. doi:10.1111/lang.12003.

    Abstract

    This study considers the role of verbal working memory in sentence comprehension in typically developing English-speaking children. Fifty-six (N = 56) children aged 4;0–6;6 completed a test of language comprehension that contained sentences which varied in complexity, standardized tests of vocabulary and nonverbal intelligence, and three tests of memory that measured the three verbal components of Baddeley's model of Working Memory (WM): the phonological loop, the episodic buffer, and the central executive. The results showed that children experienced most difficulty comprehending sentences that contained noncanonical word order (passives and object relative clauses). A series of linear mixed effects models were run to analyze the contribution of each component of WM to sentence comprehension. In contrast to most previous studies, the measure of the central executive did not predict comprehension accuracy. A canonicity by episodic buffer interaction showed that the episodic buffer measure was positively associated with better performance on the noncanonical sentences. The results are discussed with reference to capacity-limit and experience-dependent approaches to language comprehension.
  • Brand, S., & Ernestus, M. (2015). Reduction of obstruent-liquid-schwa clusters in casual French. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    This study investigated pronunciation variants of word-final obstruent-liquid-schwa (OLS) clusters in casual French and the variables predicting the absence of the phonemes in these clusters. In a dataset of 291 noun tokens extracted from a corpus of casual conversations, we observed that in 80.7% of the tokens, at least one phoneme was absent and that in no less than 15.5% the whole cluster was absent (e.g., /mis/ for ministre). Importantly, the probability of a phoneme being absent was higher if the following phoneme was absent as well. These data show that reduction can affect several phonemes at once and is not restricted to just a handful of (function) words. Moreover, our results demonstrate that the absence of each single phoneme is affected by the speaker's tendency to increase ease of articulation and to adapt a word's pronunciation variant to the time available.
  • Brand, S. (2017). The processing of reduced word pronunciation variants by natives and learners: Evidence from French casual speech. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Brandler, W. M., Morris, A. P., Evans, D. M., Scerri, T. S., Kemp, J. P., Timpson, N. J., St Pourcain, B., Davey Smith, G., Ring, S. M., Stein, J., Monaco, A. P., Talcott, J. B., Fisher, S. E., Webber, C., & Paracchini, S. (2013). Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. PLoS Genetics, 9(9): e1003751. doi:10.1371/journal.pgen.1003751.

    Abstract

    Humans display structural and functional asymmetries in brain organization, strikingly with respect to language and handedness. The molecular basis of these asymmetries is unknown. We report a genome-wide association study meta-analysis for a quantitative measure of relative hand skill in individuals with dyslexia [reading disability (RD)] (n = 728). The most strongly associated variant, rs7182874 (P = 8.68×10−9), is located in PCSK6, further supporting an association we previously reported. We also confirmed the specificity of this association in individuals with RD; the same locus was not associated with relative hand skill in a general population cohort (n = 2,666). As PCSK6 is known to regulate NODAL in the development of left/right (LR) asymmetry in mice, we developed a novel approach to GWAS pathway analysis, using gene-set enrichment to test for an over-representation of highly associated variants within the orthologs of genes whose disruption in mice yields LR asymmetry phenotypes. Four out of 15 LR asymmetry phenotypes showed an over-representation (FDR≤5%). We replicated three of these phenotypes; situs inversus, heterotaxia, and double outlet right ventricle, in the general population cohort (FDR≤5%). Our findings lead us to propose that handedness is a polygenic trait controlled in part by the molecular mechanisms that establish LR body asymmetry early in development.
  • Brandmeyer, A., Sadakata, M., Spyrou, L., McQueen, J. M., & Desain, P. (2013). Decoding of single-trial auditory mismatch responses for online perceptual monitoring and neurofeedback. Frontiers in Neuroscience, 7: 265. doi:10.3389/fnins.2013.00265.

    Abstract

    Multivariate pattern classification methods are increasingly applied to neuroimaging data in the context of both fundamental research and in brain-computer interfacing approaches. Such methods provide a framework for interpreting measurements made at the single-trial level with respect to a set of two or more distinct mental states. Here, we define an approach in which the output of a binary classifier trained on data from an auditory mismatch paradigm can be used for online tracking of perception and as a neurofeedback signal. The auditory mismatch paradigm is known to induce distinct perceptual states related to the presentation of high- and low-probability stimuli, which are reflected in event-related potential (ERP) components such as the mismatch negativity (MMN). The first part of this paper illustrates how pattern classification methods can be applied to data collected in an MMN paradigm, including discussion of the optimization of preprocessing steps, the interpretation of features and how the performance of these methods generalizes across individual participants and measurement sessions. We then go on to show that the output of these decoding methods can be used in online settings as a continuous index of single-trial brain activation underlying perceptual discrimination. We conclude by discussing several potential domains of application, including neurofeedback, cognitive monitoring and passive brain-computer interfaces

    Additional information

    Brandmeyer_etal_2013a.pdf
  • Brandmeyer, A., Farquhar, J., McQueen, J. M., & Desain, P. (2013). Decoding speech perception by native and non-native speakers using single-trial electrophysiological data. PLoS One, 8: e68261. doi:10.1371/journal.pone.0068261.

    Abstract

    Brain-computer interfaces (BCIs) are systems that use real-time analysis of neuroimaging data to determine the mental state of their user for purposes such as providing neurofeedback. Here, we investigate the feasibility of a BCI based on speech perception. Multivariate pattern classification methods were applied to single-trial EEG data collected during speech perception by native and non-native speakers. Two principal questions were asked: 1) Can differences in the perceived categories of pairs of phonemes be decoded at the single-trial level? 2) Can these same categorical differences be decoded across participants, within or between native-language groups? Results indicated that classification performance progressively increased with respect to the categorical status (within, boundary or across) of the stimulus contrast, and was also influenced by the native language of individual participants. Classifier performance showed strong relationships with traditional event-related potential measures and behavioral responses. The results of the cross-participant analysis indicated an overall increase in average classifier performance when trained on data from all participants (native and non-native). A second cross-participant classifier trained only on data from native speakers led to an overall improvement in performance for native speakers, but a reduction in performance for non-native speakers. We also found that the native language of a given participant could be decoded on the basis of EEG data with accuracy above 80%. These results indicate that electrophysiological responses underlying speech perception can be decoded at the single-trial level, and that decoding performance systematically reflects graded changes in the responses related to the phonological status of the stimuli. This approach could be used in extensions of the BCI paradigm to support perceptual learning during second language acquisition
  • Brandt, S., Nitschke, S., & Kidd, E. (2017). Priming the comprehension of German object relative clauses. Language Learning and Development, 13(3), 241-261. doi:10.1080/15475441.2016.1235500.

    Abstract

    Structural priming is a useful laboratory-based technique for investigating how children respond to temporary changes in the distribution of structures in their input. In the current study we investigated whether increasing the number of object relative clauses (RCs) in German-speaking children’s input changes their processing preferences for ambiguous RCs. Fifty-one 6-year-olds and 54 9-year-olds participated in a priming task that (i) gauged their baseline interpretations for ambiguous RC structures, (ii) primed an object-RC interpretation of ambiguous RCs, and (iii) determined whether priming persevered beyond immediate prime-target pairs. The 6-year old children showed no priming effect, whereas the 9-year-old group showed robust priming that was long lasting. Unlike in studies of priming in production, priming did not increase in magnitude when there was lexical overlap between prime and target. Overall, the results suggest that increased exposure to object RCs facilitates children’s interpretation of this otherwise infrequent structure, but only in older children. The implications for acquisition theory are discussed.
  • Brascamp, J., Klink, P., & Levelt, W. J. M. (2015). The ‘laws’ of binocular rivalry: 50 years of Levelt’s propositions. Vision Research, 109, 20-37. doi:10.1016/j.visres.2015.02.019.

    Abstract

    It has been fifty years since Levelt’s monograph On Binocular Rivalry (1965) was published, but its four propositions that describe the relation between stimulus strength and the phenomenology of binocular rivalry remain a benchmark for theorists and experimentalists even today. In this review, we will revisit the original conception of the four propositions and the scientific landscape in which this happened. We will also provide a brief update concerning distributions of dominance durations, another aspect of Levelt’s monograph that has maintained a prominent presence in the field. In a critical evaluation of Levelt’s propositions against current knowledge of binocular rivalry we will then demonstrate that the original propositions are not completely compatible with what is known today, but that they can, in a straightforward way, be modified to encapsulate the progress that has been made over the past fifty years. The resulting modified, propositions are shown to apply to a broad range of bistable perceptual phenomena, not just binocular rivalry, and they allow important inferences about the underlying neural systems. We argue that these inferences reflect canonical neural properties that play a role in visual perception in general, and we discuss ways in which future research can build on the work reviewed here to attain a better understanding of these properties
  • Brehm, L., & Goldrick, M. (2017). Distinguishing discrete and gradient category structure in language: Insights from verb-particle constructions. Journal of Experimental Psychology: Learning, Memory, and Cognition., 43(10), 1537-1556. doi:10.1037/xlm0000390.

    Abstract

    The current work uses memory errors to examine the mental representation of verb-particle constructions (VPCs; e.g., make up the story, cut up the meat). Some evidence suggests that VPCs are represented by a cline in which the relationship between the VPC and its component elements ranges from highly transparent (cut up) to highly idiosyncratic (make up). Other evidence supports a multiple class representation, characterizing VPCs as belonging to discretely separated classes differing in semantic and syntactic structure. We outline a novel paradigm to investigate the representation of VPCs in which we elicit illusory conjunctions, or memory errors sensitive to syntactic structure. We then use a novel application of piecewise regression to demonstrate that the resulting error pattern follows a cline rather than discrete classes. A preregistered replication verifies these findings, and a final preregistered study verifies that these errors reflect syntactic structure. This provides evidence for gradient rather than discrete representations across levels of representation in language processing.
  • Brehm, L., & Bock, K. (2017). Referential and lexical forces in number agreement. Language, Cognition and Neuroscience, 32(2), 129-146. doi:10.1080/23273798.2016.1234060.

    Abstract

    In work on grammatical agreement in sentence production, there are accounts of verb number formulation that emphasise the role of whole-structure properties and accounts that emphasise the role of word-driven properties. To evaluate these alternatives, we carried out two experiments that examined a referential (wholistic) contributor to agreement along with two lexical-semantic (local) factors. Both experiments gauged the accuracy and latency of inflected-verb production in order to assess how variations in grammatical number interacted with the other factors. The accuracy of verb production was modulated both by the referential effect of notional number and by the lexical-semantic effects of relatedness and category membership. As an index of agreement difficulty, latencies were little affected by either factor. The findings suggest that agreement is sensitive to referential as well as lexical forces and highlight the importance of lexical-structural integration in the process of sentence production.
  • Brehm, L., & Bock, K. (2013). What counts in grammatical number agreement? Cognition, 128(2), 149-169. doi:10.1016/j.cognition.2013.03.009.

    Abstract

    Both notional and grammatical number affect agreement during language production. To explore their workings, we investigated how semantic integration, a type of conceptual relatedness, produces variations in agreement (Solomon & Pearlmutter, 2004). These agreement variations are open to competing notional and lexical–grammatical number accounts. The notional hypothesis is that changes in number agreement reflect differences in referential coherence: More coherence yields more singularity. The lexical–grammatical hypothesis is that changes in agreement arise from competition between nouns differing in grammatical number: More competition yields more plurality. These hypotheses make opposing predictions about semantic integration. On the notional hypothesis, semantic integration promotes singular agreement. On the lexical–grammatical hypothesis, semantic integration promotes plural agreement. We tested these hypotheses with agreement elicitation tasks in two experiments. Both experiments supported the notional hypothesis, with semantic integration creating faster and more frequent singular agreement. This implies that referential coherence mediates the effect of semantic integration on number agreement.
  • Brouwer, S. (2013). Continuous recognition memory for spoken words in noise. Proceedings of Meetings on Acoustics, 19: 060117. doi:10.1121/1.4798781.

    Abstract

    Previous research has shown that talker variability affects recognition memory for spoken words (Palmeri et al., 1993). This study examines whether additive noise is similarly retained in memory for spoken words. In a continuous recognition memory task, participants listened to a list of spoken words mixed with noise consisting of a pure tone or of high-pass filtered white noise. The noise and speech were in non-overlapping frequency bands. In Experiment 1, listeners indicated whether each spoken word in the list was OLD (heard before in the list) or NEW. Results showed that listeners were as accurate and as fast at recognizing a word as old if it was repeated with the same or different noise. In Experiment 2, listeners also indicated whether words judged as OLD were repeated with the same or with a different type of noise. Results showed that listeners benefitted from hearing words presented with the same versus different noise. These data suggest that spoken words and temporally-overlapping but spectrally non-overlapping noise are retained or reconstructed together for explicit, but not for implicit recognition memory. This indicates that the extent to which noise variability is retained seems to depend on the depth of processing
  • Brouwer, S., Mitterer, H., & Huettig, F. (2013). Discourse context and the recognition of reduced and canonical spoken words. Applied Psycholinguistics, 34, 519-539. doi:10.1017/S0142716411000853.

    Abstract

    In two eye-tracking experiments we examined whether wider discourse information helps
    the recognition of reduced pronunciations (e.g., 'puter') more than the recognition of
    canonical pronunciations of spoken words (e.g., 'computer'). Dutch participants listened to
    sentences from a casual speech corpus containing canonical and reduced target words. Target
    word recognition was assessed by measuring eye fixation proportions to four printed words
    on a visual display: the target, a "reduced form" competitor, a "canonical form" competitor
    and an unrelated distractor. Target sentences were presented in isolation or with a wider
    discourse context. Experiment 1 revealed that target recognition was facilitated by wider
    discourse information. Importantly, the recognition of reduced forms improved significantly
    when preceded by strongly rather than by weakly supportive discourse contexts. This was not
    the case for canonical forms: listeners' target word recognition was not dependent on the
    degree of supportive context. Experiment 2 showed that the differential context effects in
    Experiment 1 were not due to an additional amount of speaker information. Thus, these data
    suggest that in natural settings a strongly supportive discourse context is more important for
    the recognition of reduced forms than the recognition of canonical forms.
  • Brouwer, S., & Bradlow, A. R. (2015). The effect of target-background synchronicity on speech-in-speech recognition. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    The aim of the present study was to investigate whether speech-in-speech recognition is affected by variation in the target-background timing relationship. Specifically, we examined whether within trial synchronous or asynchronous onset and offset of the target and background speech influenced speech-in-speech recognition. Native English listeners were presented with English target sentences in the presence of English or Dutch background speech. Importantly, only the short-term temporal context –in terms of onset and offset synchrony or asynchrony of the target and background speech– varied across conditions. Participants’ task was to repeat back the English target sentences. The results showed an effect of synchronicity for English-in-English but not for English-in-Dutch recognition, indicating that familiarity with the English background lead in the asynchronous English-in-English condition might have attracted attention towards the English background. Overall, this study demonstrated that speech-in-speech recognition is sensitive to the target-background timing relationship, revealing an important role for variation in the local context of the target-background relationship as it extends beyond the limits of the time-frame of the to-be-recognized target sentence.
  • Brouwer, S., & Bradlow, A. R. (2015). The temporal dynamics of spoken word recognition in adverse listening conditions. Journal of Psycholinguistic Research. Advanced online publication. doi:10.1007/s10936-015-9396-9.

    Abstract

    This study examined the temporal dynamics of spoken word recognition in noise and background speech. In two visual-world experiments, English participants listened to target words while looking at four pictures on the screen: a target (e.g. candle), an onset competitor (e.g. candy), a rhyme competitor (e.g. sandal), and an unrelated distractor (e.g. lemon). Target words were presented in quiet, mixed with broadband noise, or mixed with background speech. Results showed that lexical competition changes throughout the observation window as a function of what is presented in the background. These findings suggest that, rather than being strictly sequential, stream segregation and lexical competition interact during spoken word recognition
  • Brown, C. M., Hagoort, P., & Ter Keurs, M. (1999). Electrophysiological signatures of visual lexical processing: open en closed-class words. Journal of Cognitive Neuroscience, 11(3), 261-281.

    Abstract

    In this paper presents evidence of the disputed existence of an electrophysiological marker for the lexical-categorical distinction between open- and closed-class words. Event-related brain potentials were recorded from the scalp while subjects read a story. Separate waveforms were computed for open- and closed-class words. Two aspects of the waveforms could be reliably related to vocabulary class. The first was an early negativity in the 230- to 350-msec epoch, with a bilateral anterior predominance. This negativity was elicited by open- and closed-class words alike, was not affected by word frequency or word length, and had an earlier peak latency for closed-class words. The second was a frontal slow negative shift in the 350- to 500-msec epoch, largest over the left side of the scalp. This late negativity was only elicited by closed-class words. Although the early negativity cannot serve as a qualitative marker of the open- and closed-class distinction, it does reflect the earliest electrophysiological manifestation of the availability of categorical information from the mental lexicon. These results suggest that the brain honors the distinction between open- and closed-class words, in relation to the different roles that they play in on-line sentence processing.
  • Brown, P. (1999). Anthropologie cognitive. Anthropologie et Sociétés, 23(3), 91-119.

    Abstract

    In reaction to the dominance of universalism in the 1970s and '80s, there have recently been a number of reappraisals of the relation between language and cognition, and the field of cognitive anthropology is flourishing in several new directions in both America and Europe. This is partly due to a renewal and re-evaluation of approaches to the question of linguistic relativity associated with Whorf, and partly to the inspiration of modern developments in cognitive science. This review briefly sketches the history of cognitive anthropology and surveys current research on both sides of the Atlantic. The focus is on assessing current directions, considering in particular, by way of illustration, recent work in cultural models and on spatial language and cognition. The review concludes with an assessment of how cognitive anthropology could contribute directly both to the broader project of cognitive science and to the anthropological study of how cultural ideas and practices relate to structures and processes of human cognition.
  • Brown, A., & Gullberg, M. (2013). L1–L2 convergence in clausal packaging in Japanese and English. Bilingualism: Language and Cognition, 16, 477-494. doi:10.1017/S1366728912000491.

    Abstract

    This research received technical and financial support from Syracuse University, the Max Planck Institute for Psycholinguistics, and the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO; MPI 56-384, The Dynamics of Multilingual Processing, awarded to Marianne Gullberg and Peter Indefrey).
  • Brown, P. (2013). La estructura conversacional y la adquisición del lenguaje: El papel de la repetición en el habla de los adultos y niños tzeltales. In L. de León Pasquel (Ed.), Nuevos senderos en el studio de la adquisición de lenguas mesoamericanas: Estructura, narrativa y socialización (pp. 35-82). Mexico: CIESAS-UNAM.

    Abstract

    This is a translation of the Brown 1998 article in Journal of Linguistic Anthropology, 'Conversational structure and language acquisition: The role of repetition in Tzeltal adult and child speech'.

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  • Brown, P. (2015). Language, culture, and spatial cognition. In F. Sharifian (Ed.), Routledge Handbook on Language and Culture (pp. 294-309). London: Routledge.
  • Brown, P. (1980). How and why are women more polite: Some evidence from a Mayan community. In S. McConnell-Ginet, R. Borker, & N. Furman (Eds.), Women and language in literature and society (pp. 111-136). New York: Praeger.
  • Brown, C. M., Hagoort, P., & Swaab, T. Y. (1996). Neurophysiological evidence for a temporal disorganization in aphasic patients with comprehension deficits. In W. Widdig, I. Ohlendorff, T. A. Pollow, & J. Malin (Eds.), Aphasiatherapie im Wandel (pp. 89-122). Freiburg: Hochschul Verlag.
  • Brown, P. (1999). Repetition [Encyclopedia entry for 'Lexicon for the New Millenium', ed. Alessandro Duranti]. Journal of Linguistic Anthropology, 9(2), 223-226. doi:10.1525/jlin.1999.9.1-2.223.

    Abstract

    This is an encyclopedia entry describing conversational and interactional uses of linguistic repetition.
  • Brown, P., Pfeiler, B., de León, L., & Pye, C. (2013). The acquisition of agreement in four Mayan languages. In E. Bavin, & S. Stoll (Eds.), The acquisition of ergativity (pp. 271-306). Amsterdam: Benjamins.

    Abstract

    This paper presents results of a comparative project documenting the development of verbal agreement inflections in children learning four different Mayan languages: K’iche’, Tzeltal, Tzotzil, and Yukatek. These languages have similar inflectional paradigms: they have a generally agglutinative morphology, with transitive verbs obligatorily marked with separate cross-referencing inflections for the two core arguments (‘ergative’ and ‘absolutive’). Verbs are also inflected for aspect and mood, and they carry a ‘status suffix’ which generally marks verb transitivity and mood. At a more detailed level, the four languages differ strikingly in the realization of cross-reference marking. For each language, we examined longitudinal language production data from two children at around 2;0, 2;6, 3;0, and 3;6 years of age. We relate differences in the acquisition patterns of verbal morphology in the languages to 1) the placement of affixes, 2) phonological and prosodic prominence, 3) language-specific constraints on the various forms of the affixes, and 4) consistent vs. split ergativity, and conclude that prosodic salience accounts provide th ebest explanation for the acquisition patterns in these four languages.

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  • Brown, C. M., & Hagoort, P. (1999). The cognitive neuroscience of language: Challenges and future directions. In C. M. Brown, & P. Hagoort (Eds.), The neurocognition of language (pp. 3-14). Oxford: Oxford University Press.
  • Brown, P. (2015). Space: Linguistic expression of. In J. D. Wright (Ed.), International Encyclopedia of the Social and Behavioral Sciences (2nd ed.) Vol. 23 (pp. 89-93). Amsterdam: Elsevier. doi:10.1016/B978-0-08-097086-8.57017-2.
  • Brown, P. (2017). Politeness and impoliteness. In Y. Huang (Ed.), Oxford handbook of pragmatics (pp. 383-399). Oxford: Oxford University Press. doi:10.1093/oxfordhb/9780199697960.013.16.

    Abstract

    This article selectively reviews the literature on politeness across different disciplines—linguistics, anthropology, communications, conversation analysis, social psychology, and sociology—and critically assesses how both theoretical approaches to politeness and research on linguistic politeness phenomena have evolved over the past forty years. Major new developments include a shift from predominantly linguistic approaches to those examining politeness and impoliteness as processes that are embedded and negotiated in interactional and cultural contexts, as well as a greater focus on how both politeness and interactional confrontation and conflict fit into our developing understanding of human cooperation and universal aspects of human social interaction.

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  • Brown, P. (2015). Politeness and language. In J. D. Wright (Ed.), The International Encyclopedia of the Social and Behavioural Sciences (IESBS), (2nd ed.) (pp. 326-330). Amsterdam: Elsevier. doi:10.1016/B978-0-08-097086-8.53072-4.
  • Brown, P., & Levinson, S. C. (1999). Politeness: Some universals in language usage [Reprint]. In A. Jaworski, & N. Coupland (Eds.), The discourse reader (pp. 321-335). London: Routledge.

    Abstract

    This article is a reprint of chapter 1, the introduction to Brown and Levinson, 1987, Politeness: Some universals in language usage (Cambridge University Press).
  • Brown-Schmidt, S., & Konopka, A. E. (2015). Processes of incremental message planning during conversation. Psychonomic Bulletin & Review, 22, 833-843. doi:10.3758/s13423-014-0714-2.

    Abstract

    Speaking begins with the formulation of an intended preverbal message and linguistic encoding of this information. The transition from thought to speech occurs incrementally, with cascading planning at subsequent levels of production. In this article, we aim to specify the mechanisms that support incremental message preparation. We contrast two hypotheses about the mechanisms responsible for incorporating message-level information into a linguistic plan. According to the Initial Preparation view, messages can be encoded as fluent utterances if all information is ready before speaking begins. By contrast, on the Continuous Incrementality view, messages can be continually prepared and updated throughout the production process, allowing for fluent production even if new information is added to the message while speaking is underway. Testing these hypotheses, eye-tracked speakers in two experiments produced unscripted, conjoined noun phrases with modifiers. Both experiments showed that new message elements can be incrementally incorporated into the utterance even after articulation begins, consistent with a Continuous Incrementality view of message planning, in which messages percolate to linguistic encoding immediately as that information becomes available in the mind of the speaker. We conclude by discussing the functional role of incremental message planning in conversational speech and the situations in which this continuous incremental planning would be most likely to be observed
  • Brucato, N., Guadalupe, T., Franke, B., Fisher, S. E., & Francks, C. (2015). A schizophrenia-associated HLA locus affects thalamus volume and asymmetry. Brain, Behavior, and Immunity, 46, 311-318. doi:10.1016/j.bbi.2015.02.021.

    Abstract

    Genes of the Major Histocompatibility Complex (MHC) have recently been shown to have neuronal functions in the thalamus and hippocampus. Common genetic variants in the Human Leukocyte Antigens (HLA) region, human homologue of the MHC locus, are associated with small effects on susceptibility to schizophrenia, while volumetric changes of the thalamus and hippocampus have also been linked to schizophrenia. We therefore investigated whether common variants of the HLA would affect volumetric variation of the thalamus and hippocampus. We analyzed thalamus and hippocampus volumes, as measured using structural magnetic resonance imaging, in 1.265 healthy participants. These participants had also been genotyped using genome-wide single nucleotide polymorphism (SNP) arrays. We imputed genotypes for single nucleotide polymorphisms at high density across the HLA locus, as well as HLA allotypes and HLA amino acids, by use of a reference population dataset that was specifically targeted to the HLA region. We detected a significant association of the SNP rs17194174 with thalamus volume (nominal P=0.0000017, corrected P=0.0039), as well as additional SNPs within the same region of linkage disequilibrium. This effect was largely lateralized to the left thalamus and is localized within a genomic region previously associated with schizophrenia. The associated SNPs are also clustered within a potential regulatory element, and a region of linkage disequilibrium that spans genes expressed in the thalamus, including HLA-A. Our data indicate that genetic variation within the HLA region influences the volume and asymmetry of the human thalamus. The molecular mechanisms underlying this association may relate to HLA influences on susceptibility to schizophrenia
  • Bruggeman, L., & Janse, E. (2015). Older listeners' decreased flexibility in adjusting to changes in speech signal reliability. In M. Wolters, J. Linvingstone, B. Beattie, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). London: International Phonetic Association.

    Abstract

    Under noise or speech reductions, young adult listeners flexibly adjust the parameters of lexical activation and competition to allow for speech signal unreliability. Consequently, mismatches in the input are treated more leniently such that lexical candidates are not immediately deactivated. Using eyetracking, we assessed whether this modulation of recognition dynamics also occurs for older listeners. Dutch participants (aged 60+) heard Dutch sentences containing a critical word while viewing displays of four line drawings. The name of one picture shared either onset or rhyme with the critical word (i.e., was a phonological competitor). Sentences were either clear and noise-free, or had several phonemes replaced by bursts of noise. A larger preference for onset competitors than for rhyme competitors was observed in both clear and noise conditions; performance did not alter across condition. This suggests that dynamic adjustment of spoken-word recognition parameters in response to noise is less available to older listeners.
  • Buetti, S., Tamietto, M., Hervais-Adelman, A., Kerzel, D., de Gelder, B., & Pegna, A. J. (2013). Dissociation between goal-directed and discrete response localization in a patient with bilateral cortical blindness. Journal of Cognitive Neuroscience, 25(10), 1769-1775. doi:10.1162/jocn_a_00404.

    Abstract

    We investigated localization performance of simple targets in patient TN, who suffered bilateral damage of his primary visual cortex and shows complete cortical blindness. Using a two-alternative forced-choice paradigm, TN was asked to guess the position of left-right targets with goal-directed and discrete manual responses. The results indicate a clear dissociation between goal-directed and discrete responses. TN pointed toward the correct target location in approximately 75% of the trials but was at chance level with discrete responses. This indicates that the residual ability to localize an unseen stimulus depends critically on the possibility to translate a visual signal into a goal-directed motor output at least in certain forms of blindsight.
  • Bull, L. E., Oliver, C., Callaghan, E., & Woodcock, K. A. (2015). Increased Exposure to Rigid Routines can Lead to Increased Challenging Behavior Following Changes to Those Routines. Journal of Autism and Developmental Disorders, 45(6), 1569-1578. doi:10.1007/s10803-014-2308-2.

    Abstract

    Several neurodevelopmental disorders are associated with preference for routine and challenging behavior following changes to routines. We examine individuals with Prader–Willi syndrome, who show elevated levels of this behavior, to better understand how previous experience of a routine can affect challenging behavior elicited by disruption to that routine. Play based challenges exposed 16 participants to routines, which were either adhered to or changed. Temper outburst behaviors, heart rate and movement were measured. As participants were exposed to routines for longer before a change (between 10 and 80 min; within participants), more temper outburst behaviors were elicited by changes. Increased emotional arousal was also elicited, which was indexed by heart rate increases not driven by movement. Further study will be important to understand whether current intervention approaches that limit exposure to changes, may benefit from the structured integration of flexibility to ensure that the opportunity for routine establishment is also limited.

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  • Bulut, T., Hung, Y., Tzeng, O., & Wu, D. (2017). Neural correlates of processing sentences and compound words in Chinese. PLOS ONE, 12(12): e0188526. doi:10.1371/journal.pone.0188526.
  • Burchfield, L. A., Luk, S.-.-H.-K., Antoniou, M., & Cutler, A. (2017). Lexically guided perceptual learning in Mandarin Chinese. In Proceedings of Interspeech 2017 (pp. 576-580). doi:10.21437/Interspeech.2017-618.

    Abstract

    Lexically guided perceptual learni ng refers to the use of lexical knowledge to retune sp eech categories and thereby adapt to a novel talker’s pronunciation. This adaptation has been extensively documented, but primarily for segmental-based learning in English and Dutch. In languages with lexical tone, such as Mandarin Chinese, tonal categories can also be retuned in this way, but segmental category retuning had not been studied. We report two experiment s in which Mandarin Chinese listeners were exposed to an ambiguous mixture of [f] and [s] in lexical contexts favoring an interpretation as either [f] or [s]. Listeners were subsequently more likely to identify sounds along a continuum between [f] and [s], and to interpret minimal word pairs, in a manner consistent with this exposure. Thus lexically guided perceptual learning of segmental categories had indeed taken place, consistent with suggestions that such learning may be a universally available adaptation process
  • Burenhult, N., Hill, C., Huber, J., Van Putten, S., Rybka, K., & San Roque, L. (2017). Forests: The cross-linguistic perspective. Geographica Helvetica, 72(4), 455-464. doi:10.5194/gh-72-455-2017.

    Abstract

    Do all humans perceive, think, and talk about tree cover ("forests") in more or less the same way? International forestry programs frequently seem to operate on the assumption that they do. However, recent advances in the language sciences show that languages vary greatly as to how the landscape domain is lexicalized and grammaticalized. Different languages segment and label the large-scale environment and its features according to astonishingly different semantic principles, often in tandem with highly culture-specific practices and ideologies. Presumed basic concepts like mountain, valley, and river cannot in fact be straightforwardly translated across languages. In this paper we describe, compare, and evaluate some of the semantic diversity observed in relation to forests. We do so on the basis of first-hand linguistic field data from a global sample of indigenous categorization systems as they are manifested in the following languages: Avatime (Ghana), Duna (Papua New Guinea), Jahai (Malay Peninsula), Lokono (the Guianas), Makalero (East Timor), and Umpila/Kuuku Ya'u (Cape York Peninsula). We show that basic linguistic categories relating to tree cover vary considerably in their principles of semantic encoding across languages, and that forest is a challenging category from the point of view of intercultural translatability. This has consequences for current global policies and programs aimed at standardizing forest definitions and measurements. It calls for greater attention to categorial diversity in designing and implementing such agendas, and for receptiveness to and understanding of local indigenous classification systems in communicating those agendas on the ground.
  • Burra, N., Hervais-Adelman, A., Kerzel, D., Tamietto, M., de Gelder, B., & Pegna, A. J. (2013). Amygdala Activation for Eye Contact Despite Complete Cortical Blindness. The Journal of Neuroscience, 33(25), 10483-10489. doi:10.1523/jneurosci.3994-12.2013.

    Abstract

    Cortical blindness refers to the loss of vision that occurs after destruction of the primary visual cortex. Although there is no sensory cortex and hence no conscious vision, some cortically blind patients show amygdala activation in response to facial or bodily expressions of emotion. Here we investigated whether direction of gaze could also be processed in the absence of any functional visual cortex. A well-known patient with bilateral destruction of his visual cortex and subsequent cortical blindness was investigated in an fMRI paradigm during which blocks of faces were presented either with their gaze directed toward or away from the viewer. Increased right amygdala activation was found in response to directed compared with averted gaze. Activity in this region was further found to be functionally connected to a larger network associated with face and gaze processing. The present study demonstrates that, in human subjects, the amygdala response to eye contact does not require an intact primary visual cortex.
  • Byun, K.-S., & Byun, E.-J. (2015). Becoming Friends with International Sign. Seoul: Sign Language Dandelion.
  • Cai, Z. G., Conell, L., & Holler, J. (2013). Time does not flow without language: Spatial distance affects temporal duration regardless of movement or direction. Psychonomic Bulletin & Review, 20(5), 973-980. doi:10.3758/s13423-013-0414-3.

    Abstract

    Much evidence has suggested that people conceive of time as flowing directionally in transverse space (e.g., from left to right for English speakers). However, this phenomenon has never been tested in a fully nonlinguistic paradigm where neither stimuli nor task use linguistic labels, which raises the possibility that time is directional only when reading/writing direction has been evoked. In the present study, English-speaking participants viewed a video where an actor sang a note while gesturing and reproduced the duration of the sung note by pressing a button. Results showed that the perceived duration of the note was increased by a long-distance gesture, relative to a short-distance gesture. This effect was equally strong for gestures moving from left to right and from right to left and was not dependent on gestures depicting movement through space; a weaker version of the effect emerged with static gestures depicting spatial distance. Since both our gesture stimuli and temporal reproduction task were nonlinguistic, we conclude that the spatial representation of time is nondirectional: Movement contributes, but is not necessary, to the representation of temporal information in a transverse timeline.
  • Calandruccio, L., Brouwer, S., Van Engen, K. J., Dhar, S., & Bradlow, A. R. (2013). Masking release due to linguistic and phonetic dissimilarity between the target and masker speech. American Journal of Audiology, 22, 157-164. doi:10.1044/1059-0889(2013/12-0072.

    Abstract

    Purpose: To investigate masking release for speech maskers for linguistically and phonetically close (English and Dutch) and distant (English and Mandarin) language pairs. Method: Thirty-two monolingual speakers of English with normal audiometric thresholds participated in the study. Data are reported for an English sentence recognition task in English and for Dutch and Mandarin competing speech maskers (Experiment 1) and noise maskers (Experiment 2) that were matched either to the long-term average speech spectra or to the temporal modulations of the speech maskers from Experiment 1. Results: Listener performance increased as the target-tomasker linguistic distance increased (English-in-English < English-in-Dutch < English-in-Mandarin). Conclusion: Spectral differences between maskers can account for some, but not all, of the variation in performance between maskers; however, temporal differences did not seem to play a significant role.
  • Caldwell-Harris, C. L., Lancaster, A., Ladd, D. R., Dediu, D., & Christiansen, M. H. (2015). Factors influencing sensitivity to lexical tone in an artificial language: Implications for second language learning. Studies in Second Language Acquisition, 37(2), 335-357. doi:10.1017/S0272263114000849.

    Abstract

    This study examined whether musical training, ethnicity, and experience with a natural tone language influenced sensitivity to tone while listening to an artificial tone language. The language was designed with three tones, modeled after level-tone African languages. Participants listened to a 15-min random concatenation of six 3-syllable words. Sensitivity to tone was assessed using minimal pairs differing only in one syllable (nonword task: e.g., to-kà-su compared to ca-fí-to) or only in tone (tone task: e.g., to-kà-su compared to to-ká-su). Proficiency in an East Asian heritage language was the strongest predictor of success on the tone task. Asians without tone language experience were no better than other ethnic groups. We conclude by considering implications for research on second language learning, especially as approached through artificial language learning.
  • Calkoen, F., Vervat, C., van Pel, M., de Haas, V., Vijfhuizen, L., Eising, E., Kroes, W., Hoen, P., van den Heuvel-Eibrink, M., Egeler, R., Van Tol, M., & Ball, L. (2015). Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro. Stem Cell Research, 14(2), 198-210. doi:10.1016/j.scr.2015.01.006.

    Abstract

    Pediatric myelodysplastic syndrome (MDS) is a heterogeneous disease covering a spectrum ranging from aplasia (RCC) to myeloproliferation (RAEB(t)). In adult-type MDS there is increasing evidence for abnormal function of the bone-marrow microenvironment. Here, we extensively studied the mesenchymal stromal cells (MSCs) derived from children with MDS. MSCs were expanded from the bone-marrow of 17 MDS patients (RCC: n = 10 and advanced MDS: n = 7) and pediatric controls (n = 10). No differences were observed with respect to phenotype, differentiation capacity, immunomodulatory capacity or hematopoietic support. mRNA expression analysis by Deep-SAGE revealed increased IL-6 expression in RCC- and RAEB(t)-MDS. RCC-MDS MSC expressed increased levels of DKK3, a protein associated with decreased apoptosis. RAEB(t)-MDS revealed increased CRLF1 and decreased DAPK1 expressions. This pattern has been associated with transformation in hematopoietic malignancies. Genes reported to be differentially expressed in adult MDS-MSC did not differ between MSC of pediatric MDS and controls. An altered mRNA expression profile, associated with cell survival and malignant transformation, of MSC derived from children with MDS strengthens the hypothesis that the micro-environment is of importance in this disease. Our data support the understanding that pediatric and adult MDS are two different diseases. Further evaluation of the pathways involved might reveal additional therapy targets.
  • Calkoen, F. G., Vervat, C., Eising, E., Vijfhuizen, L. S., 't Hoen, P.-B.-A., van den Heuvel-Eibrink, M. M., & Egeler, R. M. (2015). Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia. Haematologica, 100(11), 1434-1441. doi:10.3324/haematol.2015.126938.

    Abstract

    An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the pathophysiology of hematologic malignancies in murine models. Juvenile myelomonocytic leukemia is an aggressive malignant disease affecting young infants. Here we investigated the impact of juvenile myelomonocytic leukemia on mesenchymal stromal cells. Mesenchymal stromal cells were expanded from bone marrow samples of patients at diagnosis (n=9) and after hematopoietic stem cell transplantation (n=7; from 5 patients) and from healthy children (n=10). Cells were characterized by phenotyping, differentiation, gene expression analysis (of controls and samples obtained at diagnosis) and in vitro functional studies assessing immunomodulation and hematopoietic support. Mesenchymal stromal cells from patients did not differ from controls in differentiation capacity nor did they differ in their capacity to support in vitro hematopoiesis. Deep-SAGE sequencing revealed differential mRNA expression in patient-derived samples, including genes encoding proteins involved in immunomodulation and cell-cell interaction. Selected gene expression normalized during remission after successful hematopoietic stem cell transplantation. Whereas natural killer cell activation and peripheral blood mononuclear cell proliferation were not differentially affected, the suppressive effect on monocyte to dendritic cell differentiation was increased by mesenchymal stromal cells obtained at diagnosis, but not at time of remission. This study shows that active juvenile myelomonocytic leukemia affects the immune response-related gene expression and function of mesenchymal stromal cells. In contrast, the differential gene expression of hematopoiesis-related genes could not be supported by functional data. Decreased immune surveillance might contribute to the therapy resistance and progression in juvenile myelomonocytic leukemia.
  • Callaghan, E., Holland, C., & Kessler, K. (2017). Age-Related Changes in the Ability to Switch between Temporal and Spatial Attention. Frontiers in Aging Neuroscience, 9: 28. doi:10.3389/fnagi.2017.00028.

    Abstract

    Background: Identifying age-related changes in cognition that contribute towards reduced driving performance is important for the development of interventions to improve older adults' driving and prolong the time that they can continue to drive. While driving, one is often required to switch from attending to events changing in time, to distribute attention spatially. Although there is extensive research into both spatial attention and temporal attention and how these change with age, the literature on switching between these modalities of attention is limited within any age group. Methods: Age groups (21-30, 40-49, 50-59, 60-69 and 70+ years) were compared on their ability to switch between detecting a target in a rapid serial visual presentation (RSVP) stream and detecting a target in a visual search display. To manipulate the cost of switching, the target in the RSVP stream was either the first item in the stream (Target 1st), towards the end of the stream (Target Mid), or absent from the stream (Distractor Only). Visual search response times and accuracy were recorded. Target 1st trials behaved as no-switch trials, as attending to the remaining stream was not necessary. Target Mid and Distractor Only trials behaved as switch trials, as attending to the stream to the end was required. Results: Visual search response times (RTs) were longer on "Target Mid" and "Distractor Only" trials in comparison to "Target 1st" trials, reflecting switch-costs. Larger switch-costs were found in both the 40-49 and 60-69 years group in comparison to the 21-30 years group when switching from the Target Mid condition. Discussion: Findings warrant further exploration as to whether there are age-related changes in the ability to switch between these modalities of attention while driving. If older adults display poor performance when switching between temporal and spatial attention while driving, then the development of an intervention to preserve and improve this ability would be beneficial. © 2017 Callaghan, Holland and Kessler.
  • Campisi, E., & Ozyurek, A. (2013). Iconicity as a communicative strategy: Recipient design in multimodal demonstrations for adults and children. Journal of Pragmatics, 47, 14-27. doi:10.1016/j.pragma.2012.12.007.

    Abstract

    Humans are the only species that uses communication to teach new knowledge to novices, usually to children (Tomasello, 1999 and Csibra and Gergely, 2006). This context of communication can employ “demonstrations” and it takes place with or without the help of objects (Clark, 1996). Previous research has focused on understanding the nature of demonstrations for very young children and with objects involved. However, little is known about the strategies used in demonstrating an action to an older child in comparison to another adult and without the use of objects, i.e., with gestures only. We tested if during demonstration of an action speakers use different degrees of iconicity in gestures for a child compared to an adult. 18 Italian subjects described to a camera how to make coffee imagining the listener as a 12-year-old child, a novice or an expert adult. While speech was found more informative both for the novice adult and for the child compared to the expert adult, the rate of iconic gestures increased and they were more informative and bigger only for the child compared to both of the adult conditions. Iconicity in gestures can be a powerful communicative strategy in teaching new knowledge to children in demonstrations and this is in line with claims that it can be used as a scaffolding device in grounding knowledge in experience (Perniss et al., 2010).
  • Cappuccio, M. L., Chu, M., & Kita, S. (2013). Pointing as an instrumental gesture: Gaze representation through indication. Humana.Mente: Journal of Philosophical Studies, 24, 125-149.

    Abstract

    We call those gestures “instrumental” that can enhance certain thinking processes of an agent by offering him representational models of his actions in a virtual space of imaginary performative possibilities. We argue that pointing is an instrumental gesture in that it represents geometrical information on one’s own gaze direction (i.e., a spatial model for attentional/ocular fixation/orientation), and provides a ritualized template for initiating gaze coordination and joint attention. We counter two possible objections, asserting respectively that the representational content of pointing is not constitutive, but derived from language, and that pointing directly solicits gaze coordination, without representing it. We consider two studies suggesting that attention and spatial perception are actively modified by one’s own pointing activity: the first study shows that pointing gestures help children link sets of objects to their corresponding number words; the second, that adults are faster and more accurate in counting when they point.
  • Capredon, M., Brucato, N., Tonasso, L., Choesmel-Cadamuro, V., Ricaut, F.-X., Razafindrazaka, H., Ratolojanahary, M. A., Randriamarolaza, L.-P., Champion, B., & Dugoujon, J.-M. (2013). Tracing Arab-Islamic Inheritance in Madagascar: Study of the Y-chromosome and Mitochondrial DNA in the Antemoro. PLoS One, 8(11): e80932. doi:10.1371/journal.pone.0080932.

    Abstract

    Madagascar is located at the crossroads of the Asian and African worlds and is therefore of particular interest for studies on human population migration. Within the large human diversity of the Great Island, we focused our study on a particular ethnic group, the Antemoro. Their culture presents an important Arab-Islamic influence, but the question of an Arab biological inheritance remains unresolved. We analyzed paternal (n=129) and maternal (n=135) lineages of this ethnic group. Although the majority of Antemoro genetic ancestry comes from sub-Saharan African and Southeast Asian gene pools, we observed in their paternal lineages two specific haplogroups (J1 and T1) linked to Middle Eastern origins. This inheritance was restricted to some Antemoro sub-groups. Statistical analyses tended to confirm significant Middle Eastern genetic contribution. This study gives a new perspective to the large human genetic diversity in Madagascar
  • Carota, F., Kriegeskorte, N., Nili, H., & Pulvermüller, F. (2017). Representational Similarity Mapping of Distributional Semantics in Left Inferior Frontal, Middle Temporal, and Motor Cortex. Cerebral Cortex, 27(1), 294-309. doi:10.1093/cercor/bhw379.

    Abstract

    Language comprehension engages a distributed network of frontotemporal, parietal, and sensorimotor regions, but it is still unclear how meaning of words and their semantic relationships are represented and processed within these regions and to which degrees lexico-semantic representations differ between regions and semantic types. We used fMRI and representational similarity analysis to relate word-elicited multivoxel patterns to semantic similarity between action and object words. In left inferior frontal (BA 44-45-47), left posterior middle temporal and left precentral cortex, the similarity of brain response patterns reflected semantic similarity among action-related verbs, as well as across lexical classes-between action verbs and tool-related nouns and, to a degree, between action verbs and food nouns, but not between action verbs and animal nouns. Instead, posterior inferior temporal cortex exhibited a reverse response pattern, which reflected the semantic similarity among object-related nouns, but not action-related words. These results show that semantic similarity is encoded by a range of cortical areas, including multimodal association (e.g., anterior inferior frontal, posterior middle temporal) and modality-preferential (premotor) cortex and that the representational geometries in these regions are partly dependent on semantic type, with semantic similarity among action-related words crossing lexical-semantic category boundaries.
  • Carrion Castillo, A., Maassen, B., Franke, B., Heister, A., Naber, M., Van der Leij, A., Francks, C., & Fisher, S. E. (2017). Association analysis of dyslexia candidate genes in a Dutch longitudinal sample. European Journal of Human Genetics, 25(4), 452-460. doi:10.1038/ejhg.2016.194.

    Abstract

    Dyslexia is a common specific learning disability with a substantive genetic component. Several candidate genes have been proposed to be implicated in dyslexia susceptibility, such as DYX1C1, ROBO1, KIAA0319, and DCDC2. Associations with variants in these genes have also been reported with a variety of psychometric measures tapping into the underlying processes that might be impaired in dyslexic people. In this study, we first conducted a literature review to select single nucleotide polymorphisms (SNPs) in dyslexia candidate genes that had been repeatedly implicated across studies. We then assessed the SNPs for association in the richly phenotyped longitudinal data set from the Dutch Dyslexia Program. We tested for association with several quantitative traits, including word and nonword reading fluency, rapid naming, phoneme deletion, and nonword repetition. In this, we took advantage of the longitudinal nature of the sample to examine if associations were stable across four educational time-points (from 7 to 12 years). Two SNPs in the KIAA0319 gene were nominally associated with rapid naming, and these associations were stable across different ages. Genetic association analysis with complex cognitive traits can be enriched through the use of longitudinal information on trait development.
  • Carrion Castillo, A., Franke, B., & Fisher, S. E. (2013). Molecular genetics of dyslexia: An overview. Dyslexia, 19(4), 214-240. doi:10.1002/dys.1464.

    Abstract

    Dyslexia is a highly heritable learning disorder with a complex underlying genetic architecture. Over the past decade, researchers have pinpointed a number of candidate genes that may contribute to dyslexia susceptibility. Here, we provide an overview of the state of the art, describing how studies have moved from mapping potential risk loci, through identification of associated gene variants, to characterization of gene function in cellular and animal model systems. Work thus far has highlighted some intriguing mechanistic pathways, such as neuronal migration, axon guidance, and ciliary biology, but it is clear that we still have much to learn about the molecular networks that are involved. We end the review by highlighting the past, present, and future contributions of the Dutch Dyslexia Programme to studies of genetic factors. In particular, we emphasize the importance of relating genetic information to intermediate neurobiological measures, as well as the value of incorporating longitudinal and developmental data into molecular designs
  • Casillas, M., Bergelson, E., Warlaumont, A. S., Cristia, A., Soderstrom, M., VanDam, M., & Sloetjes, H. (2017). A New Workflow for Semi-automatized Annotations: Tests with Long-Form Naturalistic Recordings of Childrens Language Environments. In Proceedings of Interspeech 2017 (pp. 2098-2102). doi:10.21437/Interspeech.2017-1418.

    Abstract

    Interoperable annotation formats are fundamental to the utility, expansion, and sustainability of collective data repositories.In language development research, shared annotation schemes have been critical to facilitating the transition from raw acoustic data to searchable, structured corpora. Current schemes typically require comprehensive and manual annotation of utterance boundaries and orthographic speech content, with an additional, optional range of tags of interest. These schemes have been enormously successful for datasets on the scale of dozens of recording hours but are untenable for long-format recording corpora, which routinely contain hundreds to thousands of audio hours. Long-format corpora would benefit greatly from (semi-)automated analyses, both on the earliest steps of annotation—voice activity detection, utterance segmentation, and speaker diarization—as well as later steps—e.g., classification-based codes such as child-vs-adult-directed speech, and speech recognition to produce phonetic/orthographic representations. We present an annotation workflow specifically designed for long-format corpora which can be tailored by individual researchers and which interfaces with the current dominant scheme for short-format recordings. The workflow allows semi-automated annotation and analyses at higher linguistic levels. We give one example of how the workflow has been successfully implemented in a large cross-database project.
  • Casillas, M., & Frank, M. C. (2017). The development of children's ability to track and predict turn structure in conversation. Journal of Memory and Language, 92, 234-253. doi:10.1016/j.jml.2016.06.013.

    Abstract

    Children begin developing turn-taking skills in infancy but take several years to fluidly integrate their growing knowledge of language into their turn-taking behavior. In two eye-tracking experiments, we measured children’s anticipatory gaze to upcoming responders while controlling linguistic cues to turn structure. In Experiment 1, we showed English and non-English conversations to English-speaking adults and children. In Experiment 2, we phonetically controlled lexicosyntactic and prosodic cues in English-only speech. Children spontaneously made anticipatory gaze switches by age two and continued improving through age six. In both experiments, children and adults made more anticipatory switches after hearing questions. Consistent with prior findings on adult turn prediction, prosodic information alone did not increase children’s anticipatory gaze shifts. But, unlike prior work with adults, lexical information alone was not sucient either—children’s performance was best overall with lexicosyntax and prosody together. Our findings support an account in which turn tracking and turn prediction emerge in infancy and then gradually become integrated with children’s online linguistic processing.
  • Casillas, M., & Frank, M. C. (2013). The development of predictive processes in children’s discourse understanding. In M. Knauff, M. Pauen, N. Sebanz, & I. Wachsmuth (Eds.), Proceedings of the 35th Annual Meeting of the Cognitive Science Society. (pp. 299-304). Austin,TX: Cognitive Society.

    Abstract

    We investigate children’s online predictive processing as it occurs naturally, in conversation. We showed 1–7 year-olds short videos of improvised conversation between puppets, controlling for available linguistic information through phonetic manipulation. Even one- and two-year-old children made accurate and spontaneous predictions about when a turn-switch would occur: they gazed at the upcoming speaker before they heard a response begin. This predictive skill relies on both lexical and prosodic information together, and is not tied to either type of information alone. We suggest that children integrate prosodic, lexical, and visual information to effectively predict upcoming linguistic material in conversation.
  • Casillas, M., De Vos, C., Crasborn, O., & Levinson, S. C. (2015). The perception of stroke-to-stroke turn boundaries in signed conversation. In D. C. Noelle, R. Dale, A. S. Warlaumont, J. Yoshimi, T. Matlock, C. D. Jennings, & P. R. Maglio (Eds.), Proceedings of the 37th Annual Meeting of the Cognitive Science Society (CogSci 2015) (pp. 315-320). Austin, TX: Cognitive Science Society.

    Abstract

    Speaker transitions in conversation are often brief, with minimal vocal overlap. Signed languages appear to defy this pattern with frequent, long spans of simultaneous signing. But recent evidence suggests that turn boundaries in signed language may only include the content-bearing parts of the turn (from the first stroke to the last), and not all turn-related movement (from first preparation to final retraction). We tested whether signers were able to anticipate “stroke-to-stroke” turn boundaries with only minimal conversational context. We found that, indeed, signers anticipated turn boundaries at the ends of turn-final strokes. Signers often responded early, especially when the turn was long or contained multiple possible end points. Early responses for long turns were especially apparent for interrogatives—long interrogative turns showed much greater anticipation compared to short ones.
  • Casillas, M., Amatuni, A., Seidl, A., Soderstrom, M., Warlaumont, A., & Bergelson, E. (2017). What do Babies hear? Analyses of Child- and Adult-Directed Speech. In Proceedings of Interspeech 2017 (pp. 2093-2097). doi:10.21437/Interspeech.2017-1409.

    Abstract

    Child-directed speech is argued to facilitate language development, and is found cross-linguistically and cross-culturally to varying degrees. However, previous research has generally focused on short samples of child-caregiver interaction, often in the lab or with experimenters present. We test the generalizability of this phenomenon with an initial descriptive analysis of the speech heard by young children in a large, unique collection of naturalistic, daylong home recordings. Trained annotators coded automatically-detected adult speech 'utterances' from 61 homes across 4 North American cities, gathered from children (age 2-24 months) wearing audio recorders during a typical day. Coders marked the speaker gender (male/female) and intended addressee (child/adult), yielding 10,886 addressee and gender tags from 2,523 minutes of audio (cf. HB-CHAAC Interspeech ComParE challenge; Schuller et al., in press). Automated speaker-diarization (LENA) incorrectly gender-tagged 30% of male adult utterances, compared to manually-coded consensus. Furthermore, we find effects of SES and gender on child-directed and overall speech, increasing child-directed speech with child age, and interactions of speaker gender, child gender, and child age: female caretakers increased their child-directed speech more with age than male caretakers did, but only for male infants. Implications for language acquisition and existing classification algorithms are discussed.
  • Catani, M., Robertsson, N., Beyh, A., Huynh, V., de Santiago Requejo, F., Howells, H., Barrett, R. L., Aiello, M., Cavaliere, C., Dyrby, T. B., Krug, K., Ptito, M., D'Arceuil, H., Forkel, S. J., & Dell'Acqua, F. (2017). Short parietal lobe connections of the human and monkey brain. Cortex, 97, 339-357. doi:10.1016/j.cortex.2017.10.022.

    Abstract

    The parietal lobe has a unique place in the human brain. Anatomically, it is at the crossroad between the frontal, occipital, and temporal lobes, thus providing a middle ground for multimodal sensory integration. Functionally, it supports higher cognitive functions that are characteristic of the human species, such as mathematical cognition, semantic and pragmatic aspects of language, and abstract thinking. Despite its importance, a comprehensive comparison of human and simian intraparietal networks is missing.

    In this study, we used diffusion imaging tractography to reconstruct the major intralobar parietal tracts in twenty-one datasets acquired in vivo from healthy human subjects and eleven ex vivo datasets from five vervet and six macaque monkeys. Three regions of interest (postcentral gyrus, superior parietal lobule and inferior parietal lobule) were used to identify the tracts. Surface projections were reconstructed for both species and results compared to identify similarities or differences in tract anatomy (i.e., trajectories and cortical projections). In addition, post-mortem dissections were performed in a human brain.

    The largest tract identified in both human and monkey brains is a vertical pathway between the superior and inferior parietal lobules. This tract can be divided into an anterior (supramarginal gyrus) and a posterior (angular gyrus) component in both humans and monkey brains. The second prominent intraparietal tract connects the postcentral gyrus to both supramarginal and angular gyri of the inferior parietal lobule in humans but only to the supramarginal gyrus in the monkey brain. The third tract connects the postcentral gyrus to the anterior region of the superior parietal lobule and is more prominent in monkeys compared to humans. Finally, short U-shaped fibres in the medial and lateral aspects of the parietal lobe were identified in both species. A tract connecting the medial parietal cortex to the lateral inferior parietal cortex was observed in the monkey brain only.

    Our findings suggest a consistent pattern of intralobar parietal connections between humans and monkeys with some differences for those areas that have cytoarchitectonically distinct features in humans. The overall pattern of intraparietal connectivity supports the special role of the inferior parietal lobule in cognitive functions characteristic of humans.
  • Ceroni, F., Simpson, N. H., Francks, C., Baird, G., Conti-Ramsden, G., Clark, A., Bolton, P. F., Hennessy, E. R., Donnelly, P., Bentley, D. R., Martin, H., IMGSAC, SLI Consortium, WGS500 Consortium, Parr, J., Pagnamenta, A. T., Maestrini, E., Bacchelli, E., Fisher, S. E., & Newbury, D. F. (2015). Reply to Pembrey et al: ‘ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis’. European Journal of Human Genetics, 23, 1113-1115. doi:10.1038/ejhg.2014.275.
  • Chang, F., Bauman, M., Pappert, S., & Fitz, H. (2015). Do lemmas speak German?: A verb position effect in German structural priming. Cognitive Science, 39(5), 1113-1130. doi:10.1111/cogs.12184.

    Abstract

    Lexicalized theories of syntax often assume that verb-structure regularities are mediated by lemmas, which abstract over variation in verb tense and aspect. German syntax seems to challenge this assumption, because verb position depends on tense and aspect. To examine how German speakers link these elements, a structural priming study was performed which varied syntactic structure, verb position (encoded by tense and aspect), and verb overlap. Abstract structural priming was found, both within and across verb position, but priming was larger when the verb position was the same between prime and target. Priming was boosted by verb overlap, but there was no interaction with verb position. The results can be explained by a lemma model where tense and aspect are linked to structural choices in German. Since the architecture of this lemma model is not consistent with results from English, a connectionist model was developed which could explain the cross-linguistic variation in the production system. Together, these findings support the view that language learning plays an important role in determining the nature of structural priming in different languages
  • Chang, F., Kidd, E., & Rowland, C. F. (2013). Prediction in processing is a by-product of language learning [Commentary on Pickering & Garrod: An integrated theory of language production and comprehension]. Behavioral and Brain Sciences, 36(4), 350-351. doi:10.1017/S0140525X12001495.

    Abstract

    Both children and adults predict the content of upcoming language, suggesting that prediction is useful for learning as well as processing. We present an alternative model which can explain prediction behaviour as a by-product of language learning. We suggest that a consideration of language acquisition places important constraints on Pickering & Garrod's (P&G's) theory.
  • Chen, A. (2015). Children’s use of intonation in reference and the role of input. In L. Serratrice, & S. E. M. Allen (Eds.), The acquisition of reference (pp. 83-104). Amsterdam: Benjamins.

    Abstract

    Studies on children’s use of intonation in reference are few in number but are diverse in terms of theoretical frameworks and intonational parameters. In the current review, I present a re-analysis of the referents in each study, using a three-dimension approach (i.e. referential givenness-newness, relational givenness-newness, contrast), discuss the use of intonation at two levels (phonetic, phonological), and compare findings from different studies within a single framework. The patterns stemming from these studies may be limited in generalisability but can serve as initial hypotheses for future work. Furthermore, I examine the role of input as available in infant direct speech in the acquisition of intonational encoding of referents. In addition, I discuss how future research can advance our knowledge.

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  • Chen, J., Calhoun, V. D., Arias-Vasquez, A., Zwiers, M. P., Van Hulzen, K., Fernández, G., Fisher, S. E., Franke, B., Turner, J. A., & Liu, J. (2015). G-Protein genomic association with normal variation in gray matter density. Human Brain Mapping, 36(11), 4272-4286. doi:10.1002/hbm.22916.

    Abstract

    While detecting genetic variations underlying brain structures helps reveal mechanisms of neural disorders, high data dimensionality poses a major challenge for imaging genomic association studies. In this work, we present the application of a recently proposed approach, parallel independent component analysis with reference (pICA-R), to investigate genomic factors potentially regulating gray matter variation in a healthy population. This approach simultaneously assesses many variables for an aggregate effect and helps to elicit particular features in the data. We applied pICA-R to analyze gray matter density (GMD) images (274,131 voxels) in conjunction with single nucleotide polymorphism (SNP) data (666,019 markers) collected from 1,256 healthy individuals of the Brain Imaging Genetics (BIG) study. Guided by a genetic reference derived from the gene GNA14, pICA-R identified a significant SNP-GMD association (r = −0.16, P = 2.34 × 10−8), implying that subjects with specific genotypes have lower localized GMD. The identified components were then projected to an independent dataset from the Mind Clinical Imaging Consortium (MCIC) including 89 healthy individuals, and the obtained loadings again yielded a significant SNP-GMD association (r = −0.25, P = 0.02). The imaging component reflected GMD variations in frontal, precuneus, and cingulate regions. The SNP component was enriched in genes with neuronal functions, including synaptic plasticity, axon guidance, molecular signal transduction via PKA and CREB, highlighting the GRM1, PRKCH, GNA12, and CAMK2B genes. Collectively, our findings suggest that GNA12 and GNA14 play a key role in the genetic architecture underlying normal GMD variation in frontal and parietal regions
  • Chen, X. S., Reader, R. H., Hoischen, A., Veltman, J. A., Simpson, N. H., Francks, C., Newbury, D. F., & Fisher, S. E. (2017). Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment. Scientific Reports, 7: 46105. doi:10.1038/srep46105.

    Abstract

    A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritable with substantial societal impact. Molecular studies have begun to identify candidate loci, but much of the underlying genetic architecture remains undetermined. We performed whole-exome sequencing of 43 unrelated probands affected by severe specific language impairment, followed by independent validations with Sanger sequencing, and analyses of segregation patterns in parents and siblings, to shed new light on aetiology. By first focusing on a pre-defined set of known candidates from the literature, we identified potentially pathogenic variants in genes already implicated in diverse language-related syndromes, including ERC1, GRIN2A, and SRPX2. Complementary analyses suggested novel putative candidates carrying validated variants which were predicted to have functional effects, such as OXR1, SCN9A and KMT2D. We also searched for potential “multiple-hit” cases; one proband carried a rare AUTS2 variant in combination with a rare inherited haplotype affecting STARD9, while another carried a novel nonsynonymous variant in SEMA6D together with a rare stop-gain in SYNPR. On broadening scope to all rare and novel variants throughout the exomes, we identified biological themes that were enriched for such variants, including microtubule transport and cytoskeletal regulation.
  • Choi, J., Cutler, A., & Broersma, M. (2017). Early development of abstract language knowledge: Evidence from perception-production transfer of birth-language memory. Royal Society Open Science, 4: 160660. doi:10.1098/rsos.160660.

    Abstract

    Children adopted early in life into another linguistic community typically forget their birth language but retain, unaware, relevant linguistic knowledge that may facilitate (re)learning of birth-language patterns. Understanding the nature of this knowledge can shed light on how language is acquired. Here, international adoptees from Korea with Dutch as their current language, and matched Dutch-native controls, provided speech production data on a Korean consonantal distinction unlike any Dutch distinctions, at the outset and end of an intensive perceptual training. The productions, elicited in a repetition task, were identified and rated by Korean listeners. Adoptees' production scores improved significantly more across the training period than control participants' scores, and, for adoptees only, relative production success correlated significantly with the rate of learning in perception (which had, as predicted, also surpassed that of the controls). Of the adoptee group, half had been adopted at 17 months or older (when talking would have begun), while half had been prelinguistic (under six months). The former group, with production experience, showed no advantage over the group without. Thus the adoptees' retained knowledge of Korean transferred from perception to production and appears to be abstract in nature rather than dependent on the amount of experience.
  • Choi, J., Broersma, M., & Cutler, A. (2017). Early phonology revealed by international adoptees' birth language retention. Proceedings of the National Academy of Sciences of the United States of America, 114(28), 7307-7312. doi:10.1073/pnas.1706405114.

    Abstract

    Until at least 6 mo of age, infants show good discrimination for familiar phonetic contrasts (i.e., those heard in the environmental language) and contrasts that are unfamiliar. Adult-like discrimination (significantly worse for nonnative than for native contrasts) appears only later, by 9–10 mo. This has been interpreted as indicating that infants have no knowledge of phonology until vocabulary development begins, after 6 mo of age. Recently, however, word recognition has been observed before age 6 mo, apparently decoupling the vocabulary and phonology acquisition processes. Here we show that phonological acquisition is also in progress before 6 mo of age. The evidence comes from retention of birth-language knowledge in international adoptees. In the largest ever such study, we recruited 29 adult Dutch speakers who had been adopted from Korea when young and had no conscious knowledge of Korean language at all. Half were adopted at age 3–5 mo (before native-specific discrimination develops) and half at 17 mo or older (after word learning has begun). In a short intensive training program, we observe that adoptees (compared with 29 matched controls) more rapidly learn tripartite Korean consonant distinctions without counterparts in their later-acquired Dutch, suggesting that the adoptees retained phonological knowledge about the Korean distinction. The advantage is equivalent for the younger-adopted and the older-adopted groups, and both groups not only acquire the tripartite distinction for the trained consonants but also generalize it to untrained consonants. Although infants younger than 6 mo can still discriminate unfamiliar phonetic distinctions, this finding indicates that native-language phonological knowledge is nonetheless being acquired at that age.
  • Choi, S., McDonough, L., Bowerman, M., & Mandler, J. M. (1999). Early sensitivity to language-specific spatial categories in English and Korean. Cognitive Development, 14, 241-268. doi:10.1016/S0885-2014(99)00004-0.

    Abstract

    This study investigates young children’s comprehension of spatial terms in two languages that categorize space strikingly differently. English makes a distinction between actions resulting in containment (put in) versus support or surface attachment (put on), while Korean makes a cross-cutting distinction between tight-fit relations (kkita) versus loose-fit or other contact relations (various verbs). In particular, the Korean verb kkita refers to actions resulting in a tight-fit relation regardless of containment or support. In a preferential looking study we assessed the comprehension of in by 20 English learners and kkita by 10 Korean learners, all between 18 and 23 months. The children viewed pairs of scenes while listening to sentences with and without the target word. The target word led children to gaze at different and language-appropriate aspects of the scenes. We conclude that children are sensitive to language-specific spatial categories by 18–23 months.
  • Choi, J., Broersma, M., & Cutler, A. (2015). Enhanced processing of a lost language: Linguistic knowledge or linguistic skill? In Proceedings of Interspeech 2015: 16th Annual Conference of the International Speech Communication Association (pp. 3110-3114).

    Abstract

    Same-different discrimination judgments for pairs of Korean stop consonants, or of Japanese syllables differing in phonetic segment length, were made by adult Korean adoptees in the Netherlands, by matched Dutch controls, and Korean controls. The adoptees did not outdo either control group on either task, although the same individuals had performed significantly better than matched controls on an identification learning task. This suggests that early exposure to multiple phonetic systems does not specifically improve acoustic-phonetic skills; rather, enhanced performance suggests retained language knowledge.
  • Christoffels, I. K., Ganushchak, L. Y., & Koester, D. (2013). Language conflict in translation; An ERP study of translation production. Journal of Cognitive Psychology, 25, 646-664. doi:10.1080/20445911.2013.821127.

    Abstract

    Although most bilinguals can translate with relative ease, the underlying neuro-cognitive processes are poorly understood. Using event-related brain potentials (ERPs) we investigated the temporal course of word translation. Participants translated words from and to their first (L1, Dutch) and second (L2, English) language while ERPs were recorded. Interlingual homographs (IHs) were included to introduce language conflict. IHs share orthographic form but have different meanings in L1 and L2 (e.g., room in Dutch refers to cream). Results showed that the brain distinguished between translation directions as early as 200 ms after word presentation: the P2 amplitudes were more positive in the L1L2 translation direction. The N400 was also modulated by translation direction, with more negative amplitudes in the L2L1 translation direction. Furthermore, the IHs were translated more slowly, induced more errors, and elicited more negative N400 amplitudes than control words. In a naming experiment, participants read aloud the same words in L1 or L2 while ERPs were recorded. Results showed no effect of either IHs or language, suggesting that task schemas may be crucially related to language control in translation. Furthermore, translation appears to involve conceptual processing in both translation directions, and the task goal appears to influence how words are processed.

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  • Clifton, C. J., Meyer, A. S., Wurm, L. H., & Treiman, R. (2013). Language comprehension and production. In A. F. Healy, & R. W. Proctor (Eds.), Handbook of Psychology, Volume 4, Experimental Psychology. 2nd Edition (pp. 523-547). Hoboken, NJ: Wiley.

    Abstract

    In this chapter, we survey the processes of recognizing and producing words and of understanding and creating sentences. Theory and research on these topics have been shaped by debates about how various sources of information are integrated in these processes, and about the role of language structure, as analyzed in the discipline of linguistics. In this chapter, we describe current views of fluent language users' comprehension of spoken and written language and their production of spoken language. We review what we consider to be the most important findings and theories in psycholinguistics, returning again and again to the questions of modularity and the importance of linguistic knowledge. Although we acknowledge the importance of social factors in language use, our focus is on core processes such as parsing and word retrieval that are not necessarily affected by such factors. We do not have space to say much about the important fields of developmental psycholinguistics, which deals with the acquisition of language by children, or applied psycholinguistics, which encompasses such topics as language disorders and language teaching. Although we recognize that there is burgeoning interest in the measurement of brain activity during language processing and how language is represented in the brain, space permits only occasional pointers to work in neuropsychology and the cognitive neuroscience of language. For treatment of these topics, and others, the interested reader could begin with two recent handbooks of psycholinguistics (Gaskell, 2007; Traxler & Gemsbacher, 2006) and a handbook of cognitive neuroscience (Gazzaniga, 2004).
  • Clifton, Jr., C., Cutler, A., McQueen, J. M., & Van Ooijen, B. (1999). The processing of inflected forms. [Commentary on H. Clahsen: Lexical entries and rules of language.]. Behavioral and Brain Sciences, 22, 1018-1019.

    Abstract

    Clashen proposes two distinct processing routes, for regularly and irregularly inflected forms, respectively, and thus is apparently making a psychological claim. We argue his position, which embodies a strictly linguistic perspective, does not constitute a psychological processing model.
  • Coco, M. I., Araujo, S., & Petersson, K. M. (2017). Disentangling stimulus plausibility and contextual congruency: Electro-physiological evidence for differential cognitive dynamics. Neuropsychologia, 96, 150-163. doi:10.1016/j.neuropsychologia.2016.12.008.

    Abstract

    Expectancy mechanisms are routinely used by the cognitive system in stimulus processing and in anticipation of appropriate responses. Electrophysiology research has documented negative shifts of brain activity when expectancies are violated within a local stimulus context (e.g., reading an implausible word in a sentence) or more globally between consecutive stimuli (e.g., a narrative of images with an incongruent end). In this EEG study, we examine the interaction between expectancies operating at the level of stimulus plausibility and at more global level of contextual congruency to provide evidence for, or against, a disassociation of the underlying processing mechanisms. We asked participants to verify the congruency of pairs of cross-modal stimuli (a sentence and a scene), which varied in plausibility. ANOVAs on ERP amplitudes in selected windows of interest show that congruency violation has longer-lasting (from 100 to 500 ms) and more widespread effects than plausibility violation (from 200 to 400 ms). We also observed critical interactions between these factors, whereby incongruent and implausible pairs elicited stronger negative shifts than their congruent counterpart, both early on (100–200 ms) and between 400–500 ms. Our results suggest that the integration mechanisms are sensitive to both global and local effects of expectancy in a modality independent manner. Overall, we provide novel insights into the interdependence of expectancy during meaning integration of cross-modal stimuli in a verification task
  • Cohen, E., & Haun, D. B. M. (2013). The development of tag-based cooperation via a socially acquired trait. Evolution and Human Behavior, 24, 230-235. doi:10.1016/j.evolhumbehav.2013.02.001.

    Abstract

    Recent theoretical models have demonstrated that phenotypic traits can support the non-random assortment of cooperators in a population, thereby permitting the evolution of cooperation. In these “tag-based models”, cooperators modulate cooperation according to an observable and hard-to-fake trait displayed by potential interaction partners. Socially acquired vocalizations in general, and speech accent among humans in particular, are frequently proposed as hard to fake and hard to hide traits that display sufficient cross-populational variability to reliably guide such social assortment in fission–fusion societies. Adults’ sensitivity to accent variation in social evaluation and decisions about cooperation is well-established in sociolinguistic research. The evolutionary and developmental origins of these biases are largely unknown, however. Here, we investigate the influence of speech accent on 5–10-year-old children's developing social and cooperative preferences across four Brazilian Amazonian towns. Two sites have a single dominant accent, and two sites have multiple co-existing accent varieties. We found that children's friendship and resource allocation preferences were guided by accent only in sites characterized by accent heterogeneity. Results further suggest that this may be due to a more sensitively tuned ear for accent variation. The demonstrated local-accent preference did not hold in the face of personal cost. Results suggest that mechanisms guiding tag-based assortment are likely tuned according to locally relevant tag-variation.

    Additional information

    Cohen_Suppl_Mat_2013.docx
  • Collins, J. (2015). ‘Give’ and semantic maps. In B. Nolan, G. Rawoens, & E. Diedrichsen (Eds.), Causation, permission, and transfer: Argument realisation in GET, TAKE, PUT, GIVE and LET verbs (pp. 129-146). Amsterdam: John Benjamins.
  • Collins, J. (2017). Real and spurious correlations involving tonal languages. In N. J. Enfield (Ed.), Dependencies in language: On the causal ontology of linguistics systems (pp. 129-139). Berlin: Language Science Press.
  • Connell, L., Cai, Z. G., & Holler, J. (2013). Do you see what I'm singing? Visuospatial movement biases pitch perception. Brain and Cognition, 81, 124-130. doi:10.1016/j.bandc.2012.09.005.

    Abstract

    The nature of the connection between musical and spatial processing is controversial. While pitch may be described in spatial terms such as “high” or “low”, it is unclear whether pitch and space are associated but separate dimensions or whether they share representational and processing resources. In the present study, we asked participants to judge whether a target vocal note was the same as (or different from) a preceding cue note. Importantly, target trials were presented as video clips where a singer sometimes gestured upward or downward while singing that target note, thus providing an alternative, concurrent source of spatial information. Our results show that pitch discrimination was significantly biased by the spatial movement in gesture, such that downward gestures made notes seem lower in pitch than they really were, and upward gestures made notes seem higher in pitch. These effects were eliminated by spatial memory load but preserved under verbal memory load conditions. Together, our findings suggest that pitch and space have a shared representation such that the mental representation of pitch is audiospatial in nature.
  • Cooper, A., Brouwer, S., & Bradlow, A. R. (2015). Interdependent processing and encoding of speech and concurrent background noise. Attention, Perception & Psychophysics, 77(4), 1342-1357. doi:10.3758/s13414-015-0855-z.

    Abstract

    Speech processing can often take place in adverse listening conditions that involve the mixing of speech and background noise. In this study, we investigated processing dependencies between background noise and indexical speech features, using a speeded classification paradigm (Garner, 1974; Exp. 1), and whether background noise is encoded and represented in memory for spoken words in a continuous recognition memory paradigm (Exp. 2). Whether or not the noise spectrally overlapped with the speech signal was also manipulated. The results of Experiment 1 indicated that background noise and indexical features of speech (gender, talker identity) cannot be completely segregated during processing, even when the two auditory streams are spectrally nonoverlapping. Perceptual interference was asymmetric, whereby irrelevant indexical feature variation in the speech signal slowed noise classification to a greater extent than irrelevant noise variation slowed speech classification. This asymmetry may stem from the fact that speech features have greater functional relevance to listeners, and are thus more difficult to selectively ignore than background noise. Experiment 2 revealed that a recognition cost for words embedded in different types of background noise on the first and second occurrences only emerged when the noise and the speech signal were spectrally overlapping. Together, these data suggest integral processing of speech and background noise, modulated by the level of processing and the spectral separation of the speech and noise.
  • Coridun, S., Ernestus, M., & Ten Bosch, L. (2015). Learning pronunciation variants in a second language: Orthographic effects. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    The present study investigated the effect of orthography on the learning and subsequent processing of pronunciation variants in a second language. Dutch learners of French learned reduced pronunciation variants that result from schwa-zero alternation in French (e.g., reduced /ʃnij/ from chenille 'caterpillar'). Half of the participants additionally learnt the words' spellings, which correspond more closely to the full variants with schwa. On the following day, participants performed an auditory lexical decision task, in which they heard half of the words in their reduced variants, and the other half in their full variants. Participants who had exclusively learnt the auditory forms performed significantly worse on full variants than participants who had also learnt the spellings. This shows that learners integrate phonological and orthographic information to process pronunciation variants. There was no difference between both groups in their performances on reduced variants, suggesting that the exposure to spelling does not impede learners' processing of these variants.
  • Cortázar-Chinarro, M., Lattenkamp, E. Z., Meyer-Lucht, Y., Luquet, E., Laurila, A., & Höglund, J. (2017). Drift, selection, or migration? Processes affecting genetic differentiation and variation along a latitudinal gradient in an amphibian. BMC Evolutionary Biology, 17: 189. doi:10.1186/s12862-017-1022-z.

    Abstract

    Past events like fluctuations in population size and post-glacial colonization processes may influence the relative importance of genetic drift, migration and selection when determining the present day patterns of genetic variation. We disentangle how drift, selection and migration shape neutral and adaptive genetic variation in 12 moor frog populations along a 1700 km latitudinal gradient. We studied genetic differentiation and variation at a MHC exon II locus and a set of 18 microsatellites.
    Results

    Using outlier analyses, we identified the MHC II exon 2 (corresponding to the β-2 domain) locus and one microsatellite locus (RCO8640) to be subject to diversifying selection, while five microsatellite loci showed signals of stabilizing selection among populations. STRUCTURE and DAPC analyses on the neutral microsatellites assigned populations to a northern and a southern cluster, reflecting two different post-glacial colonization routes found in previous studies. Genetic variation overall was lower in the northern cluster. The signature of selection on MHC exon II was weaker in the northern cluster, possibly as a consequence of smaller and more fragmented populations.
    Conclusion

    Our results show that historical demographic processes combined with selection and drift have led to a complex pattern of differentiation along the gradient where some loci are more divergent among populations than predicted from drift expectations due to diversifying selection, while other loci are more uniform among populations due to stabilizing selection. Importantly, both overall and MHC genetic variation are lower at northern latitudes. Due to lower evolutionary potential, the low genetic variation in northern populations may increase the risk of extinction when confronted with emerging pathogens and climate change.
  • Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R. B., Surakka, I., Pietiläinen, O., Kettunen, J., Anttila, V. and 50 moreCousminer, D. L., Berry, D. J., Timpson, N. J., Ang, W., Thiering, E., Byrne, E. M., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R. B., Surakka, I., Pietiläinen, O., Kettunen, J., Anttila, V., Kaakinen, M., Sovio, U., Pouta, A., Das, S., Lagou, V., Power, C., Prokopenko, I., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S., Palotie, A., Kajantie, E., Osmond, C., Lehtimäki, T., Viikari, J. S., Kähönen, M., Warrington, N. M., Lye, S. J., Palmer, L. J., Tiesler, C. M. T., Flexeder, C., Montgomery, G. W., Medland, S. E., Hofman, A., Hakonarson, H., Guxens, M., Bartels, M., Salomaa, V., Murabito, J. M., Kaprio, J., Sørensen, T. I. A., Ballester, F., Bisgaard, H., Boomsma, D. I., Koppelman, G. H., Grant, S. F. A., Jaddoe, V. W. V., Martin, N. G., Heinrich, J., Pennell, C. E., Raitakari, O. T., Eriksson, J. G., Smith, G. D., Hyppönen, E., Järvelin, M.-R., McCarthy, M. I., Ripatti, S., Widén, E., Consortium ReproGen, & Consortium Early Growth Genetics (EGG) (2013). Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22(13), 2735-2747. doi:10.1093/hmg/ddt104.

    Abstract

    The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates with adult risks for hormone-dependent cancer and adverse cardiometabolic health. The only gene so far associated with pubertal height growth, LIN28B, pleiotropically influences childhood growth, puberty and cancer progression, pointing to shared underlying mechanisms. To discover genetic loci influencing pubertal height and growth and to place them in context of overall growth and maturation, we performed genome-wide association meta-analyses in 18 737 European samples utilizing longitudinally collected height measurements. We found significant associations (P < 1.67 × 10(-8)) at 10 loci, including LIN28B. Five loci associated with pubertal timing, all impacting multiple aspects of growth. In particular, a novel variant correlated with expression of MAPK3, and associated both with increased prepubertal growth and earlier menarche. Another variant near ADCY3-POMC associated with increased body mass index, reduced pubertal growth and earlier puberty. Whereas epidemiological correlations suggest that early puberty marks a pathway from rapid prepubertal growth to reduced final height and adult obesity, our study shows that individual loci associating with pubertal growth have variable longitudinal growth patterns that may differ from epidemiological observations. Overall, this study uncovers part of the complex genetic architecture linking pubertal height growth, the timing of puberty and childhood obesity and provides new information to pinpoint processes linking these traits.
  • Cristia, A., Dupoux, E., Hakuno, Y., Lloyd-Fox, S., Schuetze, M., Kivits, J., Bergvelt, T., Van Gelder, M., Filippin, L., Charron, S., & Minagawa-Kawai, Y. (2013). An online database of infant functional Near InfraRed Spectroscopy studies: A community-augmented systematic review. PLoS One, 8(3): e58906. doi:10.1371/journal.pone.0058906.

    Abstract

    Until recently, imaging the infant brain was very challenging. Functional Near InfraRed Spectroscopy (fNIRS) is a promising, relatively novel technique, whose use is rapidly expanding. As an emergent field, it is particularly important to share methodological knowledge to ensure replicable and robust results. In this paper, we present a community-augmented database which will facilitate precisely this exchange. We tabulated articles and theses reporting empirical fNIRS research carried out on infants below three years of age along several methodological variables. The resulting spreadsheet has been uploaded in a format allowing individuals to continue adding new results, and download the most recent version of the table. Thus, this database is ideal to carry out systematic reviews. We illustrate its academic utility by focusing on the factors affecting three key variables: infant attrition, the reliability of oxygenated and deoxygenated responses, and signal-to-noise ratios. We then discuss strengths and weaknesses of the DBIfNIRS, and conclude by suggesting a set of simple guidelines aimed to facilitate methodological convergence through the standardization of reports.
  • Cristia, A. (2013). Input to language: The phonetics of infant-directed speech. Language and Linguistics Compass, 7, 157-170. doi:10.1111/lnc3.12015.

    Abstract

    Over the first year of life, infant perception changes radically as the child learns the phonology of the ambient language from the speech she is exposed to. Since infant-directed speech attracts the child's attention more than other registers, it is necessary to describe that input in order to understand language development, and to address questions of learnability. In this review, evidence from corpora analyses, experimental studies, and observational paradigms is brought together to outline the first comprehensive empirical picture of infant-directed speech and its effects on language acquisition. The ensuing landscape suggests that infant-directed speech provides an emotionally and linguistically rich input to language acquisition

    Additional information

    Cristia_Suppl_Material.xls
  • Cristia, A., Mielke, J., Daland, R., & Peperkamp, S. (2013). Similarity in the generalization of implicitly learned sound patterns. Journal of Laboratory Phonology, 4(2), 259-285.

    Abstract

    A core property of language is the ability to generalize beyond observed examples. In two experiments, we explore how listeners generalize implicitly learned sound patterns to new nonwords and to new sounds, with the goal of shedding light on how similarity affects treatment of potential generalization targets. During the exposure phase, listeners heard nonwords whose onset consonant was restricted to a subset of a natural class (e.g., /d g v z Z/). During the test phase, listeners were presented with new nonwords and asked to judge how frequently they had been presented before; some of the test items began with a consonant from the exposure set (e.g., /d/), and some began with novel consonants with varying relations to the exposure set (e.g., /b/, which is highly similar to all onsets in the training set; /t/, which is highly similar to one of the training onsets; and /p/, which is less similar than the other two). The exposure onset was rated most frequent, indicating that participants encoded onset attestation in the exposure set, and generalized it to new nonwords. Participants also rated novel consonants as somewhat frequent, indicating generalization to onsets that did not occur in the exposure phase. While generalization could be accounted for in terms of featural distance, it was insensitive to natural class structure. Generalization to new sounds was predicted better by models requiring prior linguistic knowledge (either traditional distinctive features or articulatory phonetic information) than by a model based on a linguistically naïve measure of acoustic similarity.

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