Publications

Displaying 101 - 200 of 848
  • Bürki, A., Ernestus, M., Gendrot, C., Fougeron, C., & Frauenfelder, U. H. (2011). What affects the presence versus absence of schwa and its duration: A corpus analysis of French connected speech. Journal of the Acoustical Society of America, 130, 3980-3991. doi:10.1121/1.3658386.

    Abstract

    This study presents an analysis of over 4000 tokens of words produced as variants with and without schwa in a French corpus of radio-broadcasted speech. In order to determine which of the many variables mentioned in the literature influence variant choice, 17 predictors were tested in the same analysis. Only five of these variables appeared to condition variant choice. The question of the processing stage, or locus, of this alternation process is also addressed in a comparison of the variables that predict variant choice with the variables that predict the acoustic duration of schwa in variants with schwa. Only two variables predicting variant choice also predict schwa duration. The limited overlap between the predictors for variant choice and for schwa duration, combined with the nature of these variables, suggest that the variants without schwa do not result from a phonetic process of reduction; that is, they are not the endpoint of gradient schwa shortening. Rather, these variants are generated early in the production process, either during phonological encoding or word-form retrieval. These results, based on naturally produced speech, provide a useful complement to on-line production experiments using artificial speech tasks.
  • Caldwell-Harris, C. L., Lancaster, A., Ladd, D. R., Dediu, D., & Christiansen, M. H. (2015). Factors influencing sensitivity to lexical tone in an artificial language: Implications for second language learning. Studies in Second Language Acquisition, 37(2), 335-357. doi:10.1017/S0272263114000849.

    Abstract

    This study examined whether musical training, ethnicity, and experience with a natural tone language influenced sensitivity to tone while listening to an artificial tone language. The language was designed with three tones, modeled after level-tone African languages. Participants listened to a 15-min random concatenation of six 3-syllable words. Sensitivity to tone was assessed using minimal pairs differing only in one syllable (nonword task: e.g., to-kà-su compared to ca-fí-to) or only in tone (tone task: e.g., to-kà-su compared to to-ká-su). Proficiency in an East Asian heritage language was the strongest predictor of success on the tone task. Asians without tone language experience were no better than other ethnic groups. We conclude by considering implications for research on second language learning, especially as approached through artificial language learning.
  • Calkoen, F., Vervat, C., van Pel, M., de Haas, V., Vijfhuizen, L., Eising, E., Kroes, W., Hoen, P., van den Heuvel-Eibrink, M., Egeler, R., Van Tol, M., & Ball, L. (2015). Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro. Stem Cell Research, 14(2), 198-210. doi:10.1016/j.scr.2015.01.006.

    Abstract

    Pediatric myelodysplastic syndrome (MDS) is a heterogeneous disease covering a spectrum ranging from aplasia (RCC) to myeloproliferation (RAEB(t)). In adult-type MDS there is increasing evidence for abnormal function of the bone-marrow microenvironment. Here, we extensively studied the mesenchymal stromal cells (MSCs) derived from children with MDS. MSCs were expanded from the bone-marrow of 17 MDS patients (RCC: n = 10 and advanced MDS: n = 7) and pediatric controls (n = 10). No differences were observed with respect to phenotype, differentiation capacity, immunomodulatory capacity or hematopoietic support. mRNA expression analysis by Deep-SAGE revealed increased IL-6 expression in RCC- and RAEB(t)-MDS. RCC-MDS MSC expressed increased levels of DKK3, a protein associated with decreased apoptosis. RAEB(t)-MDS revealed increased CRLF1 and decreased DAPK1 expressions. This pattern has been associated with transformation in hematopoietic malignancies. Genes reported to be differentially expressed in adult MDS-MSC did not differ between MSC of pediatric MDS and controls. An altered mRNA expression profile, associated with cell survival and malignant transformation, of MSC derived from children with MDS strengthens the hypothesis that the micro-environment is of importance in this disease. Our data support the understanding that pediatric and adult MDS are two different diseases. Further evaluation of the pathways involved might reveal additional therapy targets.
  • Calkoen, F. G., Vervat, C., Eising, E., Vijfhuizen, L. S., 't Hoen, P.-B.-A., van den Heuvel-Eibrink, M. M., & Egeler, R. M. (2015). Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia. Haematologica, 100(11), 1434-1441. doi:10.3324/haematol.2015.126938.

    Abstract

    An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the pathophysiology of hematologic malignancies in murine models. Juvenile myelomonocytic leukemia is an aggressive malignant disease affecting young infants. Here we investigated the impact of juvenile myelomonocytic leukemia on mesenchymal stromal cells. Mesenchymal stromal cells were expanded from bone marrow samples of patients at diagnosis (n=9) and after hematopoietic stem cell transplantation (n=7; from 5 patients) and from healthy children (n=10). Cells were characterized by phenotyping, differentiation, gene expression analysis (of controls and samples obtained at diagnosis) and in vitro functional studies assessing immunomodulation and hematopoietic support. Mesenchymal stromal cells from patients did not differ from controls in differentiation capacity nor did they differ in their capacity to support in vitro hematopoiesis. Deep-SAGE sequencing revealed differential mRNA expression in patient-derived samples, including genes encoding proteins involved in immunomodulation and cell-cell interaction. Selected gene expression normalized during remission after successful hematopoietic stem cell transplantation. Whereas natural killer cell activation and peripheral blood mononuclear cell proliferation were not differentially affected, the suppressive effect on monocyte to dendritic cell differentiation was increased by mesenchymal stromal cells obtained at diagnosis, but not at time of remission. This study shows that active juvenile myelomonocytic leukemia affects the immune response-related gene expression and function of mesenchymal stromal cells. In contrast, the differential gene expression of hematopoiesis-related genes could not be supported by functional data. Decreased immune surveillance might contribute to the therapy resistance and progression in juvenile myelomonocytic leukemia.
  • Cameron-Faulkner, T., & Kidd, E. (2007). I'm are what I'm are: The acquisition of first-person singular present BE. Cognitive Linguistics, 18(1), 1-22. doi:10.1515/COG.2007.001.

    Abstract

    The present study investigates the development of am in the speech of one English-speaking child, Scarlett (aged 4;6–5;6). We show that am is infrequent in the speech addressed to children; the acquisition of this form of BE presents a unique insight into the processes underlying language development because children have little evidence regarding its correct use. Scarlett produced a pervasive error where she overextended are to first-person singular contexts where am was required (e.g., I'm are trying, When are I'm finished?). Am gradually emerged in her speech on what appears to be a construction-specific basis. The findings of the study are used in support of a usage-based, constructivisit approach to language development.
  • Carlsson, K., Petrovic, P., Skare, S., Petersson, K. M., & Ingvar, M. (2000). Tickling expectations: Neural processing in anticipation of a sensory stimulus. Journal of Cognitive Neuroscience, 12(4), 691-703. doi:10.1162/089892900562318.
  • Casasanto, D. (2011). Different bodies, different minds: The body-specificity of language and thought. Current Directions in Psychological Science, 20, 378-383. doi:10.1177/0963721411422058.

    Abstract

    Do people with different kinds of bodies think differently? According to the bodyspecificity hypothesis (Casasanto 2009), they should. In this article, I review evidence that right- and left-handers, who perform actions in systematically different ways, use correspondingly different areas of the brain for imagining actions and representing the meanings of action verbs. Beyond concrete actions, the way people use their hands also influences the way they represent abstract ideas with positive and negative emotional valence like “goodness,” “honesty,” and “intelligence,” and how they communicate about them in spontaneous speech and gesture. Changing how people use their right and left hands can cause them to think differently, suggesting that motoric differences between right- and left-handers are not merely correlated with cognitive differences. Body-specific patterns of motor experience shape the way we think, communicate, and make decisions
  • Casasanto, D., & Chrysikou, E. G. (2011). When left is "Right": Motor fluency shapes abstract concepts. Psychological Science, 22, 419-422. doi:10.1177/0956797611401755.

    Abstract

    Right- and left-handers implicitly associate positive ideas like "goodness"and "honesty"more strongly with their dominant side
    of space, the side on which they can act more fluently, and negative ideas more strongly with their nondominant side. Here we show that right-handers’ tendency to associate "good" with "right" and "bad" with "left" can be reversed as a result of both
    long- and short-term changes in motor fluency. Among patients who were right-handed prior to unilateral stroke, those with disabled left hands associated "good" with "right," but those with disabled right hands associated "good" with "left,"as natural left-handers do. A similar pattern was found in healthy right-handers whose right or left hand was temporarily handicapped in the laboratory. Even a few minutes of acting more fluently with the left hand can change right-handers’ implicit associations between space and emotional valence, causing a reversal of their usual judgments. Motor experience plays a causal role in shaping abstract thought.
  • Catani, M., Craig, M. C., Forkel, S. J., Kanaan, R., Picchioni, M., Toulopoulou, T., Shergill, S., Williams, S., Murphy, D. G., & McGuire, P. (2011). Altered integrity of perisylvian language pathways in schizophrenia: Relationship to auditory hallucinations. Biological Psychiatry, 70(12), 1143-1150. doi:10.1016/j.biopsych.2011.06.013.

    Abstract

    Background: Functional neuroimaging supports the hypothesis that auditory verbal hallucinations (AVH) in schizophrenia result from altered functional connectivity between perisylvian language regions, although the extent to which AVH are also associated with an altered tract anatomy is less clear.

    Methods: Twenty-eight patients with schizophrenia subdivided into 17 subjects with a history of AVH and 11 without a history of hallucinations and 59 age- and IQ-matched healthy controls were recruited. The number of streamlines, fractional anisotropy (FA), and mean diffusivity were measured along the length of the arcuate fasciculus and its medial and lateral components.

    Results: Patients with schizophrenia had bilateral reduction of FA relative to controls in the arcuate fasciculi (p < .001). Virtual dissection of the subcomponents of the arcuate fasciculi revealed that these reductions were specific to connections between posterior temporal and anterior regions in the inferior frontal and parietal lobe. Also, compared with controls, the reduction in FA of these tracts was highest, and bilateral, in patients with AVH, but in patients without AVH, this reduction was reported only on the left.

    Conclusions: These findings point toward a supraregional network model of AVH in schizophrenia. They support the hypothesis that there may be selective vulnerability of specific anatomical connections to posterior temporal regions in schizophrenia and that extensive bilateral damage is associated with a greater vulnerability to AVH. If confirmed by further studies, these findings may advance our understanding of the anatomical factors that are protective against AVH and predictive of a treatment response.
  • Ceroni, F., Simpson, N. H., Francks, C., Baird, G., Conti-Ramsden, G., Clark, A., Bolton, P. F., Hennessy, E. R., Donnelly, P., Bentley, D. R., Martin, H., IMGSAC, SLI Consortium, WGS500 Consortium, Parr, J., Pagnamenta, A. T., Maestrini, E., Bacchelli, E., Fisher, S. E., & Newbury, D. F. (2015). Reply to Pembrey et al: ‘ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis’. European Journal of Human Genetics, 23, 1113-1115. doi:10.1038/ejhg.2014.275.
  • Chang, F., Bauman, M., Pappert, S., & Fitz, H. (2015). Do lemmas speak German?: A verb position effect in German structural priming. Cognitive Science, 39(5), 1113-1130. doi:10.1111/cogs.12184.

    Abstract

    Lexicalized theories of syntax often assume that verb-structure regularities are mediated by lemmas, which abstract over variation in verb tense and aspect. German syntax seems to challenge this assumption, because verb position depends on tense and aspect. To examine how German speakers link these elements, a structural priming study was performed which varied syntactic structure, verb position (encoded by tense and aspect), and verb overlap. Abstract structural priming was found, both within and across verb position, but priming was larger when the verb position was the same between prime and target. Priming was boosted by verb overlap, but there was no interaction with verb position. The results can be explained by a lemma model where tense and aspect are linked to structural choices in German. Since the architecture of this lemma model is not consistent with results from English, a connectionist model was developed which could explain the cross-linguistic variation in the production system. Together, these findings support the view that language learning plays an important role in determining the nature of structural priming in different languages
  • Chen, A., Den Os, E., & De Ruiter, J. P. (2007). Pitch accent type matters for online processing of information status: Evidence from natural and synthetic speech. The Linguistic Review, 24(2), 317-344. doi:10.1515/TLR.2007.012.

    Abstract

    Adopting an eyetracking paradigm, we investigated the role of H*L, L*HL, L*H, H*LH, and deaccentuation at the intonational phrase-final position in online processing of information status in British English in natural speech. The role of H*L, L*H and deaccentuation was also examined in diphonesynthetic speech. It was found that H*L and L*HL create a strong bias towards newness, whereas L*H, like deaccentuation, creates a strong bias towards givenness. In synthetic speech, the same effect was found for H*L, L*H and deaccentuation, but it was delayed. The delay may not be caused entirely by the difference in the segmental quality between synthetic and natural speech. The pitch accent H*LH, however, appears to bias participants' interpretation to the target word, independent of its information status. This finding was explained in the light of the effect of durational information at the segmental level on word recognition.
  • Chen, X. S., Penny, D., & Collins, L. J. (2011). Characterization of RNase MRP RNA and novel snoRNAs from Giardia intestinalis and Trichomonas vaginalis. BMC Genomics, 12, 550. doi:10.1186/1471-2164-12-550.

    Abstract

    Background: Eukaryotic cells possess a complex network of RNA machineries which function in RNA-processing and cellular regulation which includes transcription, translation, silencing, editing and epigenetic control. Studies of model organisms have shown that many ncRNAs of the RNA-infrastructure are highly conserved, but little is known from non-model protists. In this study we have conducted a genome-scale survey of medium-length ncRNAs from the protozoan parasites Giardia intestinalis and Trichomonas vaginalis. Results: We have identified the previously ‘missing’ Giardia RNase MRP RNA, which is a key ribozyme involved in pre-rRNA processing. We have also uncovered 18 new H/ACA box snoRNAs, expanding our knowledge of the H/ ACA family of snoRNAs. Conclusions: Results indicate that Giardia intestinalis and Trichomonas vaginalis, like their distant multicellular relatives, contain a rich infrastructure of RNA-based processing. From here we can investigate the evolution of RNA processing networks in eukaryotes.
  • Chen, X. S., Rozhdestvensky, T. S., Collins, L. J., Schmitz, J., & Penny, D. (2007). Combined experimental and computational approach to identify non-protein-coding RNAs in the deep-branching eukaryote Giardia intestinalis. Nucleic Acids Research, 35, 4619-4628. doi:10.1093/nar/gkm474.

    Abstract

    Non-protein-coding RNAs represent a large proportion of transcribed sequences in eukaryotes. These RNAs often function in large RNA–protein complexes, which are catalysts in various RNA-processing pathways. As RNA processing has become an increasingly important area of research, numerous non-messenger RNAs have been uncovered in all the model eukaryotic organisms. However, knowledge on RNA processing in deep-branching eukaryotes is still limited. This study focuses on the identification of non-protein-coding RNAs from the diplomonad parasite Giardia intestinalis, showing that a combined experimental and computational search strategy is a fast method of screening reduced or compact genomes. The analysis of our Giardia cDNA library has uncovered 31 novel candidates, including C/D-box and H/ACA box snoRNAs, as well as an unusual transcript of RNase P, and double-stranded RNAs. Subsequent computational analysis has revealed additional putative C/D-box snoRNAs. Our results will lead towards a future understanding of RNA metabolism in the deep-branching eukaryote Giardia, as more ncRNAs are characterized.
  • Chen, J. (2007). 'He cut-break the rope': Encoding and categorizing cutting and breaking events in Mandarin. Cognitive Linguistics, 18(2), 273-285. doi:10.1515/COG.2007.015.

    Abstract

    Abstract Mandarin categorizes cutting and breaking events on the basis of fine semantic distinctions in the causal action and the caused result. I demonstrate the semantics of Mandarin C&B verbs from the perspective of event encoding and categorization as well as argument structure alternations. Three semantically different types of predicates can be identified: verbs denoting the C&B action subevent, verbs encoding the C&B result subevent, and resultative verb compounds (RVC) that encode both the action and the result subevents. The first verb of an RVC is basically dyadic, whereas the second is monadic. RVCs as a whole are also basically dyadic, and do not undergo detransitivization.
  • Chen, J., Calhoun, V. D., Arias-Vasquez, A., Zwiers, M. P., Van Hulzen, K., Fernández, G., Fisher, S. E., Franke, B., Turner, J. A., & Liu, J. (2015). G-Protein genomic association with normal variation in gray matter density. Human Brain Mapping, 36(11), 4272-4286. doi:10.1002/hbm.22916.

    Abstract

    While detecting genetic variations underlying brain structures helps reveal mechanisms of neural disorders, high data dimensionality poses a major challenge for imaging genomic association studies. In this work, we present the application of a recently proposed approach, parallel independent component analysis with reference (pICA-R), to investigate genomic factors potentially regulating gray matter variation in a healthy population. This approach simultaneously assesses many variables for an aggregate effect and helps to elicit particular features in the data. We applied pICA-R to analyze gray matter density (GMD) images (274,131 voxels) in conjunction with single nucleotide polymorphism (SNP) data (666,019 markers) collected from 1,256 healthy individuals of the Brain Imaging Genetics (BIG) study. Guided by a genetic reference derived from the gene GNA14, pICA-R identified a significant SNP-GMD association (r = −0.16, P = 2.34 × 10−8), implying that subjects with specific genotypes have lower localized GMD. The identified components were then projected to an independent dataset from the Mind Clinical Imaging Consortium (MCIC) including 89 healthy individuals, and the obtained loadings again yielded a significant SNP-GMD association (r = −0.25, P = 0.02). The imaging component reflected GMD variations in frontal, precuneus, and cingulate regions. The SNP component was enriched in genes with neuronal functions, including synaptic plasticity, axon guidance, molecular signal transduction via PKA and CREB, highlighting the GRM1, PRKCH, GNA12, and CAMK2B genes. Collectively, our findings suggest that GNA12 and GNA14 play a key role in the genetic architecture underlying normal GMD variation in frontal and parietal regions
  • Chen, A. (2011). Tuning information packaging: Intonational realization of topic and focus in child Dutch. Journal of Child Language, 38, 1055-1083. doi:10.1017/S0305000910000541.

    Abstract

    This study examined how four- to five-year-olds and seven- to eight-year-olds used intonation (accent placement and accent type) to encode topic and focus in Dutch. Naturally spoken declarative sentences with either sentence-initial topic and sentence-final focus or sentence-initial focus and sentence-final topic were elicited via a picture-matching game. Results showed that the four- to five-year-olds were adult-like in topic-marking, but were not yet fully adult-like in focus-marking, in particular, in the use of accent type in sentence-final focus (i.e. showing no preference for H*L). Between age five and seven, the use of accent type was further developed. In contrast to the four- to five-year-olds, the seven- to eight-year-olds showed a preference for H*L in sentence-final focus. Furthermore, they used accent type to distinguish sentence-initial focus from sentence-initial topic in addition to phonetic cues.
  • Cho, T., McQueen, J. M., & Cox, E. A. (2007). Prosodically driven phonetic detail in speech processing: The case of domain-initial strengthening in English. Journal of Phonetics, 35(2), 210-243. doi:10.1016/j.wocn.2006.03.003.

    Abstract

    We explore the role of the acoustic consequences of domain-initial strengthening in spoken-word recognition. In two cross-modal identity-priming experiments, listeners heard sentences and made lexical decisions to visual targets, presented at the onset of the second word in two-word sequences containing lexical ambiguities (e.g., bus tickets, with the competitor bust). These sequences contained Intonational Phrase (IP) or Prosodic Word (Wd) boundaries, and the second word's initial Consonant and Vowel (CV, e.g., [tI]) was spliced from another token of the sequence in IP- or Wd-initial position. Acoustic analyses showed that IP-initial consonants were articulated more strongly than Wd-initial consonants. In Experiment 1, related targets were post-boundary words (e.g., tickets). No strengthening effect was observed (i.e., identity priming effects did not vary across splicing conditions). In Experiment 2, related targets were pre-boundary words (e.g., bus). There was a strengthening effect (stronger priming when the post-boundary CVs were spliced from IP-initial than from Wd-initial position), but only in Wd-boundary contexts. These were the conditions where phonetic detail associated with domain-initial strengthening could assist listeners most in lexical disambiguation. We discuss how speakers may strengthen domain-initial segments during production and how listeners may use the resulting acoustic correlates of prosodic strengthening during word recognition.
  • Cho, T., & McQueen, J. M. (2011). Perceptual recovery from consonant-cluster simplification using language-specific phonological knowledge. Journal of Psycholinguistic Research, 40, 253-274. doi:10.1007/s10936-011-9168-0.

    Abstract

    Two experiments examined whether perceptual recovery from Korean consonant-cluster simplification is based on language-specific phonological knowledge. In tri-consonantal C1C2C3 sequences such as /lkt/ and /lpt/ in Seoul Korean, either C1 or C2 can be completely deleted. Seoul Koreans monitored for C2 targets (/p/ or / k/, deleted or preserved) in the second word of a two-word phrase with an underlying /l/-C2-/t/ sequence. In Experiment 1 the target-bearing words had contextual lexical-semantic support. Listeners recovered deleted targets as fast and as accurately as preserved targets with both Word and Intonational Phrase (IP) boundaries between the two words. In Experiment 2, contexts were low-pass filtered. Listeners were still able to recover deleted targets as well as preserved targets in IP-boundary contexts, but better with physically-present targets than with deleted targets in Word-boundary contexts. This suggests that the benefit of having target acoustic-phonetic information emerges only when higher-order (contextual and phrase-boundary) information is not available. The strikingly efficient recovery of deleted phonemes with neither acoustic-phonetic cues nor contextual support demonstrates that language-specific phonological knowledge, rather than language-universal perceptual processes which rely on fine-grained phonetic details, is employed when the listener perceives the results of a continuous-speech process in which reduction is phonetically complete.
  • Choi, S., McDonough, L., Bowerman, M., & Mandler, J. M. (1999). Early sensitivity to language-specific spatial categories in English and Korean. Cognitive Development, 14, 241-268. doi:10.1016/S0885-2014(99)00004-0.

    Abstract

    This study investigates young children’s comprehension of spatial terms in two languages that categorize space strikingly differently. English makes a distinction between actions resulting in containment (put in) versus support or surface attachment (put on), while Korean makes a cross-cutting distinction between tight-fit relations (kkita) versus loose-fit or other contact relations (various verbs). In particular, the Korean verb kkita refers to actions resulting in a tight-fit relation regardless of containment or support. In a preferential looking study we assessed the comprehension of in by 20 English learners and kkita by 10 Korean learners, all between 18 and 23 months. The children viewed pairs of scenes while listening to sentences with and without the target word. The target word led children to gaze at different and language-appropriate aspects of the scenes. We conclude that children are sensitive to language-specific spatial categories by 18–23 months.
  • Cholin, J., Dell, G. S., & Levelt, W. J. M. (2011). Planning and articulation in incremental word production: Syllable-frequency effects in English. Journal of Experimental Psychology: Learning, Memory, and Cognition, 37, 109-122. doi:10.1037/a0021322.

    Abstract

    We investigated the role of syllables during speech planning in English by measuring syllable-frequency effects. So far, syllable-frequency effects in English have not been reported. English has poorly defined syllable boundaries, and thus the syllable might not function as a prominent unit in English speech production. Speakers produced either monosyllabic (Experiment 1) or disyllabic (Experiment 2–4) pseudowords as quickly as possible in response to symbolic cues. Monosyllabic targets consisted of either high- or low-frequency syllables, whereas disyllabic items contained either a 1st or 2nd syllable that was frequency-manipulated. Significant syllable-frequency effects were found in all experiments. Whereas previous findings for disyllables in Dutch and Spanish—languages with relatively clear syllable boundaries—showed effects of a frequency manipulation on 1st but not 2nd syllables, in our study English speakers were sensitive to the frequency of both syllables. We interpret this sensitivity as an indication that the production of English has more extensive planning scopes at the interface of phonetic encoding and articulation.
  • Christoffels, I. K., Formisano, E., & Schiller, N. O. (2007). The neural correlates of verbal feedback processing: An fMRI study employing overt speech. Human Brain Mapping, 28(9), 868-879. doi:10.1002/hbm.20315.

    Abstract

    Speakers use external auditory feedback to monitor their own speech. Feedback distortion has been found to increase activity in the superior temporal areas. Using fMRI, the present study investigates the neural correlates of processing verbal feedback without distortion. In a blocked design, the following conditions were presented: (1) overt picture-naming, (2) overt picture-naming while pink noise was presented to mask external feedback, (3) covert picture-naming, (4) listening to the picture names (previously recorded from participants' own voices), and (5) listening to pink noise. The results show that auditory feedback processing involves a network of different areas related to general performance monitoring and speech-motor control. These include the cingulate cortex and the bilateral insula, supplementary motor area, bilateral motor areas, cerebellum, thalamus and basal ganglia. Our findings suggest that the anterior cingulate cortex, which is often implicated in error-processing and conflict-monitoring, is also engaged in ongoing speech monitoring. Furthermore, in the superior temporal gyrus, we found a reduced response to speaking under normal feedback conditions. This finding is interpreted in the framework of a forward model according to which, during speech production, the sensory consequence of the speech-motor act is predicted to attenuate the sensitivity of the auditory cortex. Hum Brain Mapp 2007. © 2007 Wiley-Liss, Inc.
  • Christoffels, I. K., Firk, C., & Schiller, N. O. (2007). Bilingual language control: An event-related brain potential study. Brain Research, 1147, 192-208. doi:10.1016/j.brainres.2007.01.137.

    Abstract

    This study addressed how bilingual speakers switch between their first and second language when speaking. Event-related brain potentials (ERPs) and naming latencies were measured while unbalanced German (L1)-Dutch (L2) speakers performed a picture-naming task. Participants named pictures either in their L1 or in their L2 (blocked language conditions), or participants switched between their first and second language unpredictably (mixed language condition). Furthermore, form similarity between translation equivalents (cognate status) was manipulated. A cognate facilitation effect was found for L1 and L2 indicating phonological activation of the non-response language in blocked and mixed language conditions. The ERP data also revealed small but reliable effects of cognate status. Language switching resulted in equal switching costs for both languages and was associated with a modulation in the ERP waveforms (time windows 275-375 ms and 375-475 ms). Mixed language context affected especially the L1, both in ERPs and in latencies, which became slower in L1 than L2. It is suggested that sustained and transient components of language control should be distinguished. Results are discussed in relation to current theories of bilingual language processing.
  • Chu, M., & Kita, S. (2011). The nature of gestures’ beneficial role in spatial problem solving. Journal of Experimental Psychology: General, 140, 102-116. doi:10.1037/a0021790.

    Abstract

    Co-thought gestures are hand movements produced in silent, noncommunicative, problem-solving situations. In the study, we investigated whether and how such gestures enhance performance in spatial visualization tasks such as a mental rotation task and a paper folding task. We found that participants gestured more often when they had difficulties solving mental rotation problems Experiment 1). The gesture-encouraged group solved more mental rotation problems correctly than did the gesture-allowed and gesture-prohibited groups (Experiment 2). Gestures produced by the gesture-encouraged group enhanced performance in the very trials in which they were produced Experiments 2 & 3). Furthermore, gesture frequency decreased as the participants in the gesture-encouraged group solved more problems (Experiments 2 & 3). In addition, the advantage of the gesture-encouraged group persisted into subsequent spatial visualization problems in which gesturing was prohibited: another mental rotation block (Experiment 2) and a newly introduced paper folding task (Experiment 3). The results indicate that when people have difficulty in solving spatial visualization problems, they spontaneously produce gestures to help them, and gestures can indeed improve performance. As they solve more problems, the spatial computation supported by gestures becomes internalized, and the gesture frequency decreases. The benefit of gestures persists even in subsequent spatial visualization problems in which gesture is prohibited. Moreover, the beneficial effect of gesturing can be generalized to a different spatial visualization task when two tasks require similar spatial transformation processes. We conclude that gestures enhance performance on spatial visualization tasks by improving the internal computation of spatial transformations.
  • Cleary, R. A., Poliakoff, E., Galpin, A., Dick, J. P., & Holler, J. (2011). An investigation of co-speech gesture production during action description in Parkinson’s disease. Parkinsonism & Related Disorders, 17, 753-756. doi:10.1016/j.parkreldis.2011.08.001.

    Abstract

    Methods
    The present study provides a systematic analysis of co-speech gestures which spontaneously accompany the description of actions in a group of PD patients (N = 23, Hoehn and Yahr Stage III or less) and age-matched healthy controls (N = 22). The analysis considers different co-speech gesture types, using established classification schemes from the field of gesture research. The analysis focuses on the rate of these gestures as well as on their qualitative nature. In doing so, the analysis attempts to overcome several methodological shortcomings of research in this area.
    Results
    Contrary to expectation, gesture rate was not significantly affected in our patient group, with relatively mild PD. This indicates that co-speech gestures could compensate for speech problems. However, while gesture rate seems unaffected, the qualitative precision of gestures representing actions was significantly reduced.
    Conclusions
    This study demonstrates the feasibility of carrying out fine-grained, detailed analyses of gestures in PD and offers insights into an as yet neglected facet of communication in patients with PD. Based on the present findings, an important next step is the closer investigation of the qualitative changes in gesture (including different communicative situations) and an analysis of the heterogeneity in co-speech gesture production in PD.
  • Clifton, Jr., C., Cutler, A., McQueen, J. M., & Van Ooijen, B. (1999). The processing of inflected forms. [Commentary on H. Clahsen: Lexical entries and rules of language.]. Behavioral and Brain Sciences, 22, 1018-1019.

    Abstract

    Clashen proposes two distinct processing routes, for regularly and irregularly inflected forms, respectively, and thus is apparently making a psychological claim. We argue his position, which embodies a strictly linguistic perspective, does not constitute a psychological processing model.
  • Cohen, E. (2011). Broadening the critical perspective on supernatural punishment theories. Religion, Brain & Behavior, 1(1), 70-72. doi:10.1080/2153599X.2011.558709.
  • Cohen, E., Burdett, E., Knight, N., & Barrett, J. (2011). Cross-cultural similarities and differences in person-body reasoning: Experimental evidence from the United Kingdom and Brazilian Amazon. Cognitive Science, 35, 1282-1304. doi:10.1111/j.1551-6709.2011.01172.x.

    Abstract

    We report the results of a cross-cultural investigation of person-body reasoning in the United Kingdom and northern Brazilian Amazon (Marajo´ Island). The study provides evidence that directly bears upon divergent theoretical claims in cognitive psychology and anthropology, respectively, on the cognitive origins and cross-cultural incidence of mind-body dualism. In a novel reasoning task, we found that participants across the two sample populations parsed a wide range of capacities similarly in terms of the capacities’ perceived anchoring to bodily function. Patterns of reasoning concerning the respective roles of physical and biological properties in sustaining various capacities did vary between sample populations, however. Further, the data challenge prior ad-hoc categorizations in the empirical literature on the developmental origins of and cognitive constraints on psycho-physical reasoning (e.g., in afterlife concepts). We suggest cross-culturally validated categories of ‘‘Body Dependent’’ and ‘‘Body Independent’’ items for future developmental and cross-cultural research in this emerging area.
  • Cooper, A., Brouwer, S., & Bradlow, A. R. (2015). Interdependent processing and encoding of speech and concurrent background noise. Attention, Perception & Psychophysics, 77(4), 1342-1357. doi:10.3758/s13414-015-0855-z.

    Abstract

    Speech processing can often take place in adverse listening conditions that involve the mixing of speech and background noise. In this study, we investigated processing dependencies between background noise and indexical speech features, using a speeded classification paradigm (Garner, 1974; Exp. 1), and whether background noise is encoded and represented in memory for spoken words in a continuous recognition memory paradigm (Exp. 2). Whether or not the noise spectrally overlapped with the speech signal was also manipulated. The results of Experiment 1 indicated that background noise and indexical features of speech (gender, talker identity) cannot be completely segregated during processing, even when the two auditory streams are spectrally nonoverlapping. Perceptual interference was asymmetric, whereby irrelevant indexical feature variation in the speech signal slowed noise classification to a greater extent than irrelevant noise variation slowed speech classification. This asymmetry may stem from the fact that speech features have greater functional relevance to listeners, and are thus more difficult to selectively ignore than background noise. Experiment 2 revealed that a recognition cost for words embedded in different types of background noise on the first and second occurrences only emerged when the noise and the speech signal were spectrally overlapping. Together, these data suggest integral processing of speech and background noise, modulated by the level of processing and the spectral separation of the speech and noise.
  • Cozijn, R., Noordman, L. G., & Vonk, W. (2011). Propositional integration and world-knowledge inference: Processes in understanding because sentences. Discourse Processes, 48, 475-500. doi:10.1080/0163853X.2011.594421.

    Abstract

    The issue addressed in this study is whether propositional integration and world-knowledge inference can be distinguished as separate processes during the comprehension of Dutch omdat (because) sentences. “Propositional integration” refers to the process by which the reader establishes the type of relation between two clauses or sentences. “World-knowledge inference” refers to the process of deriving the general causal relation and checking it against the reader's world knowledge. An eye-tracking experiment showed that the presence of the conjunction speeds up the processing of the words immediately following the conjunction, and slows down the processing of the sentence final words in comparison to the absence of the conjunction. A second, subject-paced reading experiment replicated the reading time findings, and the results of a verification task confirmed that the effect at the end of the sentence was due to inferential processing. The findings evidence integrative processing and inferential processing, respectively.
  • Cozijn, R., Commandeur, E., Vonk, W., & Noordman, L. G. (2011). The time course of the use of implicit causality information in the processing of pronouns: A visual world paradigm study. Journal of Memory and Language, 64, 381-403. doi:10.1016/j.jml.2011.01.001.

    Abstract

    Several theoretical accounts have been proposed with respect to the issue how quickly the implicit causality verb bias affects the understanding of sentences such as “John beat Pete at the tennis match, because he had played very well”. They can be considered as instances of two viewpoints: the focusing and the integration account. The focusing account claims that the bias should be manifest soon after the verb has been processed, whereas the integration account claims that the interpretation is deferred until disambiguating information is encountered. Up to now, this issue has remained unresolved because materials or methods have failed to address it conclusively. We conducted two experiments that exploited the visual world paradigm and ambiguous pronouns in subordinate because clauses. The first experiment presented implicit causality sentences with the task to resolve the ambiguous pronoun. To exclude strategic processing, in the second experiment, the task was to answer simple comprehension questions and only a minority of the sentences contained implicit causality verbs. In both experiments, the implicit causality of the verb had an effect before the disambiguating information was available. This result supported the focusing account.
  • Cristia, A., McGuire, G. L., Seidl, A., & Francis, A. L. (2011). Effects of the distribution of acoustic cues on infants' perception of sibilants. Journal of Phonetics, 39, 388-402. doi:10.1016/j.wocn.2011.02.004.

    Abstract

    A current theoretical view proposes that infants converge on the speech categories of their native language by attending to frequency distributions that occur in the acoustic input. To date, the only empirical support for this statistical learning hypothesis comes from studies where a single, salient dimension was manipulated. Additional evidence is sought here, by introducing a less salient pair of categories supported by multiple cues. We exposed English-learning infants to a multi-cue bidimensional grid ranging between retroflex and alveolopalatal sibilants in prevocalic position. This contrast is substantially more difficult according to previous cross-linguistic and perceptual research, and its perception is driven by cues in both the consonantal and the following vowel portions. Infants heard one of two distributions (flat, or with two peaks), and were tested with sounds varying along only one dimension. Infants' responses differed depending on the familiarization distribution, and their performance was equally good for the vocalic and the frication dimension, lending some support to the statistical hypothesis even in this harder learning situation. However, learning was restricted to the retroflex category, and a control experiment showed that lack of learning for the alveolopalatal category was not due to the presence of a competing category. Thus, these results contribute fundamental evidence on the extent and limitations of the statistical hypothesis as an explanation for infants' perceptual tuning.
  • Cristia, A. (2011). Fine-grained variation in caregivers' speech predicts their infants' discrimination. Journal of the Acoustical Society of America, 129, 3271-3280. doi:10.1121/1.3562562.

    Abstract

    Within the debate on the mechanisms underlying infants’ perceptual acquisition, one hypothesis proposes that infants’ perception is directly affected by the acoustic implementation of sound categories in the speech they hear. In consonance with this view, the present study shows that individual variation in fine-grained, subphonemic aspects of the acoustic realization of /s/ in caregivers’ speech predicts infants’ discrimination of this sound from the highly similar /∫/, suggesting that learning based on acoustic cue distributions may indeed drive natural phonological acquisition.
  • Cristia, A., Seidl, A., & Gerken, L. (2011). Learning classes of sounds in infancy. University of Pennsylvania Working Papers in Linguistics, 17, 9.

    Abstract

    Adults' phonotactic learning is affected by perceptual biases. One such bias concerns learning of constraints affecting groups of sounds: all else being equal, learning constraints affecting a natural class (a set of sounds sharing some phonetic characteristic) is easier than learning a constraint affecting an arbitrary set of sounds. This perceptual bias could be a given, for example, the result of innately guided learning; alternatively, it could be due to human learners’ experience with sounds. Using artificial grammars, we investigated whether such a bias arises in development, or whether it is present as soon as infants can learn phonotactics. Seven-month-old English-learning infants fail to generalize a phonotactic pattern involving fricatives and nasals, which does not form a coherent phonetic group, but succeed with the natural class of oral and nasal stops. In this paper, we report an experiment that explored whether those results also follow in a cohort of 4-month-olds. Unlike the older infants, 4-month-olds were able to generalize both groups, suggesting that the perceptual bias that makes phonotactic constraints on natural classes easier to learn is likely the effect of experience.
  • Cronin, K. A., Van Leeuwen, E. J. C., Mulenga, I. C., & Bodamer, M. D. (2011). Behavioral response of a chimpanzee mother toward her dead infant. American Journal of Primatology, 73(5), 415-421. doi:10.1002/ajp.20927.

    Abstract

    The mother-offspring bond is one of the strongest and most essential social bonds. Following is a detailed behavioral report of a female chimpanzee two days after her 16-month-old infant died, on the first day that the mother is observed to create distance between her and the corpse. A series of repeated approaches and retreats to and from the body are documented, along with detailed accounts of behaviors directed toward the dead infant by the mother and other group members. The behavior of the mother toward her dead infant not only highlights the maternal contribution to the mother-infant relationship but also elucidates the opportunities chimpanzees have to learn about the sensory cues associated with death, and the implications of death for the social environment.
  • Cronin, K. A., De Groot, E., & Stevens, J. M. G. (2015). Bonobos show limited social tolerance in a group setting: A comparison with chimpanzees and a test of the Relational Model. Folia primatologica, 86, 164-177. doi:10.1159/000373886.

    Abstract

    Social tolerance is a core aspect of primate social relationships with implications for the evolution of cooperation, prosociality and social learning. We measured the social tolerance of bonobos in an experiment recently validated with chimpanzees to allow for a comparative assessment of group-level tolerance, and found that the bonobo group studied here exhibited lower social tolerance on average than chimpanzees. Furthermore, following the Relational Model [de Waal, 1996], we investigated whether bonobos responded to an increased potential for social conflict with tolerance, conflict avoidance or conflict escalation, and found that only behaviours indicative of conflict escalation differed across conditions. Taken together, these findings contribute to the current debate over the level of social tolerance of bonobos and lend support to the position that the social tolerance of bonobos may not be notably high compared with other primates.
  • Cronin, K. A., Acheson, D. J., Hernández, P., & Sánchez, A. (2015). Hierarchy is Detrimental for Human Cooperation. Scientific Reports, 5: 18634. doi:10.1038/srep18634.

    Abstract

    Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species.
  • Cutler, A., Sebastian-Galles, N., Soler-Vilageliu, O., & Van Ooijen, B. (2000). Constraints of vowels and consonants on lexical selection: Cross-linguistic comparisons. Memory & Cognition, 28, 746-755.

    Abstract

    Languages differ in the constitution of their phonemic repertoire and in the relative distinctiveness of phonemes within the repertoire. In the present study, we asked whether such differences constrain spoken-word recognition, via two word reconstruction experiments, in which listeners turned non-words into real words by changing single sounds. The experiments were carried out in Dutch (which has a relatively balanced vowel-consonant ratio and many similar vowels) and in Spanish (which has many more consonants than vowels and high distinctiveness among the vowels). Both Dutch and Spanish listeners responded significantly faster and more accurately when required to change vowels as opposed to consonants; when allowed to change any phoneme, they more often altered vowels than consonants. Vowel information thus appears to constrain lexical selection less tightly (allow more potential candidates) than does consonant information, independent of language-specific phoneme repertoire and of relative distinctiveness of vowels.
  • Cutler, A., & Van de Weijer, J. (2000). De ontdekking van de eerste woorden. Stem-, Spraak- en Taalpathologie, 9, 245-259.

    Abstract

    Spraak is continu, er zijn geen betrouwbare signalen waardoor de luisteraar weet waar het ene woord eindigt en het volgende begint. Voor volwassen luisteraars is het segmenteren van gesproken taal in afzonderlijke woorden dus niet onproblematisch, maar voor een kind dat nog geen woordenschat bezit, vormt de continuïteit van spraak een nog grotere uitdaging. Desalniettemin produceren de meeste kinderen hun eerste herkenbare woorden rond het begin van het tweede levensjaar. Aan deze vroege spraakproducties gaat een formidabele perceptuele prestatie vooraf. Tijdens het eerste levensjaar - met name gedurende de tweede helft - ontwikkelt de spraakperceptie zich van een algemeen fonetisch discriminatievermogen tot een selectieve gevoeligheid voor de fonologische contrasten die in de moedertaal voorkomen. Recent onderzoek heeft verder aangetoond dat kinderen, lang voordat ze ook maar een enkel woord kunnen zeggen, in staat zijn woorden die kenmerkend zijn voor hun moedertaal te onderscheiden van woorden die dat niet zijn. Bovendien kunnen ze woorden die eerst in isolatie werden aangeboden herkennen in een continue spraakcontext. Het dagelijkse taalaanbod aan een kind van deze leeftijd maakt het in zekere zin niet gemakkelijk, bijvoorbeeld doordat de meeste woorden niet in isolatie voorkomen. Toch wordt het kind ook wel houvast geboden, onder andere doordat het woordgebruik beperkt is.
  • Cutler, A. (1982). Idioms: the older the colder. Linguistic Inquiry, 13(2), 317-320. Retrieved from http://www.jstor.org/stable/4178278?origin=JSTOR-pdf.
  • Cutler, A. (2011). Listening to REAL second language. AATSEEL Newsletter, 54(3), 14.
  • Cutler, A., & Fay, D. A. (1982). One mental lexicon, phonologically arranged: Comments on Hurford’s comments. Linguistic Inquiry, 13, 107-113. Retrieved from http://www.jstor.org/stable/4178262.
  • Cutler, A. (2015). Representation of second language phonology. Applied Psycholinguistics, 36(1), 115-128. doi:10.1017/S0142716414000459.

    Abstract

    Orthographies encode phonological information only at the level of words (chiefly, the information encoded concerns phonetic segments; in some cases, tonal information or default stress may be encoded). Of primary interest to second language (L2) learners is whether orthography can assist in clarifying L2 phonological distinctions that are particularly difficult to perceive (e.g., where one native-language phonemic category captures two L2 categories). A review of spoken-word recognition evidence suggests that orthographic information can install knowledge of such a distinction in lexical representations but that this does not affect learners’ ability to perceive the phonemic distinction in speech. Words containing the difficult phonemes become even harder for L2 listeners to recognize, because perception maps less accurately to lexical content.
  • Cutler, A., & Norris, D. (1999). Sharpening Ockham’s razor (Commentary on W.J.M. Levelt, A. Roelofs & A.S. Meyer: A theory of lexical access in speech production). Behavioral and Brain Sciences, 22, 40-41.

    Abstract

    Language production and comprehension are intimately interrelated; and models of production and comprehension should, we argue, be constrained by common architectural guidelines. Levelt et al.'s target article adopts as guiding principle Ockham's razor: the best model of production is the simplest one. We recommend adoption of the same principle in comprehension, with consequent simplification of some well-known types of models.
  • Cutler, A., & Otake, T. (1999). Pitch accent in spoken-word recognition in Japanese. Journal of the Acoustical Society of America, 105, 1877-1888.

    Abstract

    Three experiments addressed the question of whether pitch-accent information may be exploited in the process of recognizing spoken words in Tokyo Japanese. In a two-choice classification task, listeners judged from which of two words, differing in accentual structure, isolated syllables had been extracted ~e.g., ka from baka HL or gaka LH!; most judgments were correct, and listeners’ decisions were correlated with the fundamental frequency characteristics of the syllables. In a gating experiment, listeners heard initial fragments of words and guessed what the words were; their guesses overwhelmingly had the same initial accent structure as the gated word even when only the beginning CV of the stimulus ~e.g., na- from nagasa HLL or nagashi LHH! was presented. In addition, listeners were more confident in guesses with the same initial accent structure as the stimulus than in guesses with different accent. In a lexical decision experiment, responses to spoken words ~e.g., ame HL! were speeded by previous presentation of the same word ~e.g., ame HL! but not by previous presentation of a word differing only in accent ~e.g., ame LH!. Together these findings provide strong evidence that accentual information constrains the activation and selection of candidates for spoken-word recognition.
  • Dahan, D., & Gaskell, M. G. (2007). The temporal dynamics of ambiguity resolution: Evidence from spoken-word recognition. Journal of Memory and Language, 57(4), 483-501. doi:10.1016/j.jml.2007.01.001.

    Abstract

    Two experiments examined the dynamics of lexical activation in spoken-word recognition. In both, the key materials were pairs of onset-matched picturable nouns varying in frequency. Pictures associated with these words, plus two distractor pictures were displayed. A gating task, in which participants identified the picture associated with gradually lengthening fragments of spoken words, examined the availability of discriminating cues in the speech waveforms for these pairs. There was a clear frequency bias in participants’ responses to short, ambiguous fragments, followed by a temporal window in which discriminating information gradually became available. A visual-world experiment examined speech contingent eye movements. Fixation analyses suggested that frequency influences lexical competition well beyond the point in the speech signal at which the spoken word has been fully discriminated from its competitor (as identified using gating). Taken together, these data support models in which the processing dynamics of lexical activation are a limiting factor on recognition speed, over and above the temporal unfolding of the speech signal.
  • Daller, M. H., Treffers-Daller, J., & Furman, R. (2011). Transfer of conceptualization patterns in bilinguals: The construal of motion events in Turkish and German. Bilingualism: Language and Cognition, 14(1), 95-119. doi:10.1017/S1366728910000106.

    Abstract

    In the present article we provide evidence for the occurrence of transfer of conceptualization patterns in narratives of two German-Turkish bilingual groups. All bilingual participants grew up in Germany, but only one group is still resident in Germany (n = 49). The other, the returnees, moved back to Turkey after having lived in Germany for thirteen years (n = 35). The study is based on the theoretical framework for conceptual transfer outlined in Jarvis and Pavlenko (2008) and on the typology of satellite-framed and verb-framed languages developed by Talmy (1985, 1991, 2000a, b) and Slobin (1987, 1996, 2003, 2004, 2005, 2006). In the present study we provide evidence for the hypothesis that language structure affects the organization of information structure at the level of the Conceptualizer, and show that bilingual speakers’ conceptualization of motion events is influenced by the dominant linguistic environment in both languages (German for the group in Germany and Turkish for the returnees). The returnees follow the Turkish blueprints for the conceptualization of motion, in both Turkish and German event construals, whereas the German-resident bilinguals follow the German blueprints, when speaking German as well as Turkish. We argue that most of the patterns found are the result of transfer of conceptualization patterns from the dominant language of the environment.
  • Davids, N., Segers, E., Van den Brink, D., Mitterer, H., van Balkom, H., Hagoort, P., & Verhoeven, L. (2011). The nature of auditory discrimination problems in children with specific language impairment: An MMN study. Neuropsychologia, 49, 19-28. doi:10.1016/j.neuropsychologia.2010.11.001.

    Abstract

    Many children with Specific Language Impairment (SLI) show impairments in discriminating auditorily presented stimuli. The present study investigates whether these discrimination problems are speech specific or of a general auditory nature. This was studied by using a linguistic and nonlinguistic contrast that were matched for acoustic complexity in an active behavioral task and a passive ERP paradigm, known to elicit the mismatch negativity (MMN). In addition, attention skills and a variety of language skills were measured. Participants were 25 five-year-old Dutch children with SLI having receptive as well as productive language problems and 25 control children with typical speechand language development. At the behavioral level, the SLI group was impaired in discriminating the linguistic contrast as compared to the control group, while both groups were unable to distinguish the non-linguistic contrast. Moreover, the SLI group tended to have impaired attention skills which correlated with performance on most of the language tests. At the neural level, the SLI group, in contrast to the control group, did not show an MMN in response to either the linguistic or nonlinguistic contrast. The MMN data are consistent with an account that relates the symptoms in children with SLI to non-speech processing difficulties.
  • Davidson, D., & Indefrey, P. (2011). Error-related activity and correlates of grammatical plasticity. Frontiers in Psychology, 2: 219. doi:10.3389/fpsyg.2011.00219.

    Abstract

    Cognitive control involves not only the ability to manage competing task demands, but also the ability to adapt task performance during learning. This study investigated how violation-, response-, and feedback-related electrophysiological (EEG) activity changes over time during language learning. Twenty-two Dutch learners of German classified short prepositional phrases presented serially as text. The phrases were initially presented without feedback during a pre-test phase, and then with feedback in a training phase on two separate days spaced 1 week apart. The stimuli included grammatically correct phrases, as well as grammatical violations of gender and declension. Without feedback, participants' classification was near chance and did not improve over trials. During training with feedback, behavioral classification improved and violation responses appeared to both types of violation in the form of a P600. Feedback-related negative and positive components were also present from the first day of training. The results show changes in the electrophysiological responses in concert with improving behavioral discrimination, suggesting that the activity is related to grammar learning.
  • Davidson, D. J., & Indefrey, P. (2007). An inverse relation between event-related and time–frequency violation responses in sentence processing. Brain Research, 1158, 81-92. doi:10.1016/j.brainres.2007.04.082.

    Abstract

    The relationship between semantic and grammatical processing in sentence comprehension was investigated by examining event-related potential (ERP) and event-related power changes in response to semantic and grammatical violations. Sentences with semantic, phrase structure, or number violations and matched controls were presented serially (1.25 words/s) to 20 participants while EEG was recorded. Semantic violations were associated with an N400 effect and a theta band increase in power, while grammatical violations were associated with a P600 effect and an alpha/beta band decrease in power. A quartile analysis showed that for both types of violations, larger average violation effects were associated with lower relative amplitudes of oscillatory activity, implying an inverse relation between ERP amplitude and event-related power magnitude change in sentence processing.
  • Dediu, D. (2011). Are languages really independent from genes? If not, what would a genetic bias affecting language diversity look like? Human Biology, 83, 279-296. doi:10.3378/027.083.0208.

    Abstract

    It is generally accepted that the relationship between human genes
    and language is very complex and multifaceted. This has its roots in the
    “regular” complexity governing the interplay among genes and between genes
    and environment for most phenotypes, but with the added layer of supraontogenetic
    and supra-individual processes defining culture. At the coarsest
    level, focusing on the species, it is clear that human-specific—but not necessarily
    faculty-specific—genetic factors subtend our capacity for language and a
    currently very productive research program is aiming at uncovering them. At the
    other end of the spectrum, it is uncontroversial that individual-level variations in
    different aspects related to speech and language have an important genetic
    component and their discovery and detailed characterization have already started
    to revolutionize the way we think about human nature. However, at the
    intermediate, glossogenetic/population level, the relationship becomes controversial,
    partly due to deeply ingrained beliefs about language acquisition and
    universality and partly because of confusions with a different type of genelanguages
    correlation due to shared history. Nevertheless, conceptual, mathematical
    and computational models—and, recently, experimental evidence from
    artificial languages and songbirds—have repeatedly shown that genetic biases
    affecting the acquisition or processing of aspects of language and speech can be
    amplified by population-level intergenerational cultural processes and made
    manifest either as fixed “universal” properties of language or as structured
    linguistic diversity. Here, I review several such models as well as the recently
    proposed case of a causal relationship between the distribution of tone languages
    and two genes related to brain growth and development, ASPM and Microcephalin,
    and I discuss the relevance of such genetic biasing for language
    evolution, change, and diversity.
  • Dediu, D. (2011). A Bayesian phylogenetic approach to estimating the stability of linguistic features and the genetic biasing of tone. Proceedings of the Royal Society of London/B, 278(1704), 474-479. doi:10.1098/rspb.2010.1595.

    Abstract

    Language is a hallmark of our species and understanding linguistic diversity is an area of major interest. Genetic factors influencing the cultural transmission of language provide a powerful and elegant explanation for aspects of the present day linguistic diversity and a window into the emergence and evolution of language. In particular, it has recently been proposed that linguistic tone—the usage of voice pitch to convey lexical and grammatical meaning—is biased by two genes involved in brain growth and development, ASPM and Microcephalin. This hypothesis predicts that tone is a stable characteristic of language because of its ‘genetic anchoring’. The present paper tests this prediction using a Bayesian phylogenetic framework applied to a large set of linguistic features and language families, using multiple software implementations, data codings, stability estimations, linguistic classifications and outgroup choices. The results of these different methods and datasets show a large agreement, suggesting that this approach produces reliable estimates of the stability of linguistic data. Moreover, linguistic tone is found to be stable across methods and datasets, providing suggestive support for the hypothesis of genetic influences on its distribution.
  • Dediu, D., & Ladd, D. R. (2007). Linguistic tone is related to the population frequency of the adaptive haplogroups of two brain size genes, ASPM and Microcephalin. PNAS, 104, 10944-10949. doi:10.1073/pnas.0610848104.

    Abstract

    The correlations between interpopulation genetic and linguistic diversities are mostly noncausal (spurious), being due to historical processes and geographical factors that shape them in similar ways. Studies of such correlations usually consider allele frequencies and linguistic groupings (dialects, languages, linguistic families or phyla), sometimes controlling for geographic, topographic, or ecological factors. Here, we consider the relation between allele frequencies and linguistic typological features. Specifically, we focus on the derived haplogroups of the brain growth and development-related genes ASPM and Microcephalin, which show signs of natural selection and a marked geographic structure, and on linguistic tone, the use of voice pitch to convey lexical or grammatical distinctions. We hypothesize that there is a relationship between the population frequency of these two alleles and the presence of linguistic tone and test this hypothesis relative to a large database (983 alleles and 26 linguistic features in 49 populations), showing that it is not due to the usual explanatory factors represented by geography and history. The relationship between genetic and linguistic diversity in this case may be causal: certain alleles can bias language acquisition or processing and thereby influence the trajectory of language change through iterated cultural transmission.

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  • Dell, G. S., Reed, K. D., Adams, D. R., & Meyer, A. S. (2000). Speech errors, phonotactic constraints, and implicit learning: A study of the role of experience in language production. Journal of Experimental Psychology: Learning, Memory, and Cognition, 26, 1355-1367. doi:10.1037/0278-7393.26.6.1355.

    Abstract

    Speech errors follow the phonotactics of the language being spoken. For example, in English, if [n] is mispronounced as [n] the [n] will always appear in a syllable coda. The authors created an analogue to this phenomenon by having participants recite lists of consonant-vowel-consonant syllables in 4 sessions on different days. In the first 2 experiments, some consonants were always onsets, some were always codas, and some could be both. In a third experiment, the set of possible onsets and codas depended on vowel identity. In all 3 studies, the production errors that occurred respected the "phonotactics" of the experiment. The results illustrate the implicit learning of the sequential constraints present in the stimuli and show that the language production system adapts to recent experience.
  • Deriziotis, P., André, R., Smith, D. M., Goold, R., Kinghorn, K. J., Kristiansen, M., Nathan, J. A., Rosenzweig, R., Krutauz, D., Glickman, M. H., Collinge, J., Goldberg, A. L., & Tabrizi, S. J. (2011). Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry. EMBO Journal, 30(15), 3065-3077. doi:10.1038/emboj.2011.224.

    Abstract

    * Deriziotis, P., André, R., and Smith. D.M. contributed equally to this work * - Prion diseases are associated with the conversion of cellular prion protein (PrP(C)) to toxic β-sheet isoforms (PrP(Sc)), which are reported to inhibit the ubiquitin-proteasome system (UPS). Accordingly, UPS substrates accumulate in prion-infected mouse brains, suggesting impairment of the 26S proteasome. A direct interaction between its 20S core particle and PrP isoforms was demonstrated by immunoprecipitation. β-PrP aggregates associated with the 20S particle, but did not impede binding of the PA26 complex, suggesting that the aggregates do not bind to its ends. Aggregated β-PrP reduced the 20S proteasome's basal peptidase activity, and the enhanced activity induced by C-terminal peptides from the 19S ATPases or by the 19S regulator itself, including when stimulated by polyubiquitin conjugates. However, the 20S proteasome was not inhibited when the gate in the α-ring was open due to a truncation mutation or by association with PA26/PA28. These PrP aggregates inhibit by stabilising the closed conformation of the substrate entry channel. A similar inhibition of substrate entry into the proteasome may occur in other neurodegenerative diseases where misfolded β-sheet-rich proteins accumulate.

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  • Dietrich, C., Swingley, D., & Werker, J. F. (2007). Native language governs interpretation of salient speech sound differences at 18 months. Proceedings of the National Academy of Sciences of the USA, 104(41), 16027-16031.

    Abstract

    One of the first steps infants take in learning their native language is to discover its set of speech-sound categories. This early development is shown when infants begin to lose the ability to differentiate some of the speech sounds their language does not use, while retaining or improving discrimination of language-relevant sounds. However, this aspect of early phonological tuning is not sufficient for language learning. Children must also discover which of the phonetic cues that are used in their language serve to signal lexical distinctions. Phonetic variation that is readily discriminable to all children may indicate two different words in one language but only one word in another. Here, we provide evidence that the language background of 1.5-year-olds affects their interpretation of phonetic variation in word learning, and we show that young children interpret salient phonetic variation in language-specific ways. Three experiments with a total of 104 children compared Dutch- and English-learning 18-month-olds' responses to novel words varying in vowel duration or vowel quality. Dutch learners interpreted vowel duration as lexically contrastive, but English learners did not, in keeping with properties of Dutch and English. Both groups performed equivalently when differentiating words varying in vowel quality. Thus, at one and a half years, children's phonological knowledge already guides their interpretation of salient phonetic variation. We argue that early phonological learning is not just a matter of maintaining the ability to distinguish language-relevant phonetic cues. Learning also requires phonological interpretation at appropriate levels of linguistic analysis.
  • Dietrich, W., & Drude, S. (Eds.). (2015). Variation in Tupi languages: Genealogy, language change, and typology [Special Issue]. Boletim do Museu Paraense Emilio Goeldi:Ciencias Humanas, 10(2).
  • Dietrich, W., & Drude, S. (2015). Variation in Tupi languages: Genealogy, language change, and typology: Introduction. Boletim do Museu Paraense Emilio Goeldi:Ciencias Humanas, 10, 213-215. doi:10.1590/1981-81222015000200002.
  • Dimitrova, D. V., Stowe, L. A., & Hoeks, J. C. (2015). When correction turns positive: Processing corrective prosody in Dutch. PLoS One, 10(5): e0126299. doi:10.1371/journal.pone.0126299.

    Abstract

    Current research on spoken language does not provide a consistent picture as to whether prosody, the melody and rhythm of speech, conveys a specific meaning. Perception studies show that English listeners assign meaning to prosodic patterns, and, for instance, associate some accents with contrast, whereas Dutch listeners behave more controversially. In two ERP studies we tested how Dutch listeners process words carrying two types of accents, which either provided new information (new information accents) or corrected information (corrective accents), both in single sentences (experiment 1) and after corrective and new information questions (experiment 2). In both experiments corrective accents elicited a sustained positivity as compared to new information accents, which started earlier in context than in single sentences. The positivity was not modulated by the nature of the preceding question, suggesting that the underlying neural mechanism likely reflects the construction of an interpretation to the accented word, either by identifying an alternative in context or by inferring it when no context is present. Our experimental results provide strong evidence for inferential processes related to prosodic contours in Dutch
  • Dimroth, C., & Klein, W. (2007). Den Erwachsenen überlegen: Kinder entwickeln beim Sprachenlernen besondere Techniken und sind erfolgreicher als ältere Menschen. Tagesspiegel, 19737, B6-B6.

    Abstract

    The younger - the better? This paper discusses second language learning at different ages and takes a critical look at generalizations of the kind ‘The younger – the better’. It is argued that these generalizations do not apply across the board. Age related differences like the amount of linguistic knowledge, prior experience as a language user, or more or less advanced communicative needs affect different components of the language system to different degrees, and can even be an advantage for the early development of simple communicative systems.
  • Dimroth, C., & Watorek, M. (2000). The scope of additive particles in basic learner languages. Studies in Second Language Acquisition, 22, 307-336. Retrieved from http://journals.cambridge.org/action/displayAbstract?aid=65981.

    Abstract

    Based on their longitudinal analysis of the acquisition of Dutch, English, French, and German, Klein and Perdue (1997) described a “basic learner variety” as valid cross-linguistically and comprising a limited number of shared syntactic patterns interacting with two types of constraints: (a) semantic—the NP whose referent has highest control comes first, and (b) pragmatic—the focus expression is in final position. These authors hypothesized that “the topic-focus structure also plays an important role in some other respects. . . . Thus, negation and (other) scope particles occur at the topic-focus boundary” (p. 318). This poses the problem of the interaction between the core organizational principles of the basic variety and optional items such as negative particles and scope particles, which semantically affect the whole or part of the utterance in which they occur. In this article, we test the validity of these authors' hypothesis for the acquisition of the additive scope particle also (and its translation equivalents). Our analysis is based on the European Science Foundation (ESF) data originally used to define the basic variety, but we also included some more advanced learner data from the same database. In doing so, we refer to the analyses of Dimroth and Klein (1996), which concern the interaction between scope particles and the part of the utterance they affect, and we make a distinction between maximal scope—that which is potentially affected by the particle—and the actual scope of a particle in relation to an utterance in a given discourse context

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  • Dingemanse, M., & Enfield, N. J. (2015). Ungeschriebene Gesetze. Gehirn und Geist, 8, 34-39.
  • Dingemanse, M., & Van Leeuwen, T. (2015). Boekoeboekoe is mollig: Taal als samenspel van de zintuigen. Onze Taal, (12), 344-345.
  • Dingemanse, M., Blasi, D. E., Lupyan, G., Christiansen, M. H., & Monaghan, P. (2015). Arbitrariness, iconicity and systematicity in language. Trends in Cognitive Sciences, 19(10), 603-615. doi:10.1016/j.tics.2015.07.013.

    Abstract

    The notion that the form of a word bears an arbitrary relation to its meaning accounts only partly for the attested form to meaning correspondences in the world’s languages. Recent research suggests a more textured view of vocabulary structure, in which arbitrariness is complemented by iconicity (aspects of form resemble aspects of meaning) and systematicity (statistical regularities in forms predict function). Experimental evidence suggests these form to meaning correspondences serve different functions in language processing, development and communication: systematicity facilities category learning by means of phonological cues, iconicity facilitates word learning and communication by means of perceptuomotor analogies, and arbitrariness facilitates meaning individuation through distinctive forms. Processes of cultural evolution help explain how these competing motivations shape vocabulary structure.
  • Dingemanse, M. (2015). Ideophones and Reduplication: Depiction, Description, and the Interpretation of Repeated Talk in Discourse. Studies in Language, 39(4), 946-970. doi:10.1075/sl.39.4.05din.

    Abstract

    Repetition is one of the most basic operations on talk, often discussed for its iconic meanings. Ideophones are marked words that depict sensory imagery, often identified by their reduplicated forms. Yet not all reduplication is iconic, and not all ideophones are reduplicated. This paper discusses the semantics and pragmatics of repeated talk (repetition as well as reduplication), with special focus on the intersection of reduplicative processes and ideophonic words. Various formal features of ideophones suggest that it is fruitful to distinguish two modes of representation in language —description and depiction— along with cues like prosodic foregrounding that can steer listeners’ interpretation from one to the other. What is special about reduplication is that it can naturally partake in both of these modes of representation, which is why it is so common in ideophones as well as in other areas of grammar. Using evidence from Siwu, Korean, Semai and a range of other languages, this paper shows how the study of ideophones sheds light on the interpretation of repeated talk and can lead to a more holistic understanding of reduplicative phenomena in language.
  • Dingemanse, M. (2011). Ideophones and the aesthetics of everyday language in a West-African society. The Senses & Society, 6(1), 77-85. doi:10.2752/174589311X12893982233830.

    Abstract

    This article explores language, culture, and the perceptual world as reflected in a particular linguistic device: ideophones, marked words that depict sensory imagery. Data from a range of elicitation tasks shows that ideophones are a key resource in talking about sensory perception in Siwu. Their use in everyday conversations underlines their communicative versatility while at the same time showing that people delight in their expressiveness. In ideophones, we have an expressive resource that combines sheer playfulness with extraordinary precision
  • Dingemanse, M., & Enfield, N. J. (2015). Other-initiated repair across languages: Towards a typology of conversational structures. Open Linguistics, 1, 98-118. doi:10.2478/opli-2014-0007.

    Abstract

    This special issue reports on a cross-linguistic study of other-initiated repair, a domain at the crossroads of language, mind, and social life. Other-initiated repair is part of a system of practices that people use to deal with problems of speaking, hearing and understanding. The contributions in this special issue describe the linguistic resources and interactional practices associated with other-initiated repair in ten different languages. Here we provide an overview of the research methods and the conceptual framework. The empirical base for the project consists of corpora of naturally occurring conversations, collected in fieldsites around the world. Methodologically, we combine qualitative analysis with a comparative-typological perspective, and we formulate principles for the cross-linguistic comparison of conversational structures. A key move, of broad relevance to pragmatic typology, is the recognition that formats for repair initiation form paradigm-like systems that are ultimately language-specific, and that comparison is best done at the level of the constitutive properties of these formats. These properties can be functional (concerning aspects of linguistic formatting) as well as sequential (concerning aspects of the interactional environment). We show how functional and sequential aspects of conversational structure can capture patterns of commonality and diversity in conversational structures within and across languages
  • Dingemanse, M. (2015). Other-initiated repair in Siwu. Open Linguistics, 1, 232-255. doi:10.1515/opli-2015-0001.

    Abstract

    This article describes the interactional patterns and linguistic structures associated with other-initiated repair in Siwu, a Kwa language spoken in eastern Ghana. Other-initiated repair is the set of techniques used by people to deal with problems in speaking, hearing and understanding. Formats for repair initiation in Siwu exploit language-specific resources like question words and noun class morphology. At the same time, the basic structure of the system bears a strong similarity other-initiated repair in other languages. Practices described for Siwu thus are potentially of broader relevance to the study of other-initiated repair. This article documents how different prosodic realisations of repair initiators may index social actions and features of the speech event; how two distinct roles of repetition in repair initiators are kept apart by features of turn design; and what kinds of items can be treated as ‘dispensable’ in resayings. By charting how other-initiated repair uses local linguistic resources and yet is shaped by interactional needs that transcend particular languages, this study contributes to the growing field of pragmatic typology: the study of systems of language use and the principles that shape them
  • Dingemanse, M., Roberts, S. G., Baranova, J., Blythe, J., Drew, P., Floyd, S., Gisladottir, R. S., Kendrick, K. H., Levinson, S. C., Manrique, E., Rossi, G., & Enfield, N. J. (2015). Universal Principles in the Repair of Communication Problems. PLoS One, 10(9): e0136100. doi:10.1371/journal.pone.0136100.

    Abstract

    There would be little adaptive value in a complex communication system like human language if there were no ways to detect and correct problems. A systematic comparison of conversation in a broad sample of the world’s languages reveals a universal system for the real-time resolution of frequent breakdowns in communication. In a sample of 12 languages of 8 language families of varied typological profiles we find a system of ‘other-initiated repair’, where the recipient of an unclear message can signal trouble and the sender can repair the original message. We find that this system is frequently used (on average about once per 1.4 minutes in any language), and that it has detailed common properties, contrary to assumptions of radical cultural variation. Unrelated languages share the same three functionally distinct types of repair initiator for signalling problems and use them in the same kinds of contexts. People prefer to choose the type that is the most specific possible, a principle that minimizes cost both for the sender being asked to fix the problem and for the dyad as a social unit. Disruption to the conversation is kept to a minimum, with the two-utterance repair sequence being on average no longer that the single utterance which is being fixed. The findings, controlled for historical relationships, situation types and other dependencies, reveal the fundamentally cooperative nature of human communication and offer support for the pragmatic universals hypothesis: while languages may vary in the organization of grammar and meaning, key systems of language use may be largely similar across cultural groups. They also provide a fresh perspective on controversies about the core properties of language, by revealing a common infrastructure for social interaction which may be the universal bedrock upon which linguistic diversity rests.
  • Dow, D. J., Huxley-Jones, J., Hall, J. M., Francks, C., Maycox, P. R., Kew, J. N., Gloger, I. S., Mehta, N. A., Kelly, F. M., Muglia, P., Breen, G., Jugurnauth, S., Pederoso, I., St.Clair, D., Rujescu, D., & Barnes, M. R. (2011). ADAMTSL3 as a candidate gene for schizophrenia: Gene sequencing and ultra-high density association analysis by imputation. Schizophrenia Research, 127(1-3), 28-34. doi:10.1016/j.schres.2010.12.009.

    Abstract

    We previously reported an association with a putative functional variant in the ADAMTSL3 gene, just below genome-wide significance in a genome-wide association study of schizophrenia. As variants impacting the function of ADAMTSL3 (a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like-3) could illuminate a novel disease mechanism and a potentially specific target, we have used complementary approaches to further evaluate the association. We imputed genotypes and performed high density association analysis using data from the HapMap and 1000 genomes projects. To review all variants that could potentially cause the association, and to identify additional possible pathogenic rare variants, we sequenced ADAMTSL3 in 92 schizophrenics. A total of 71 ADAMTSL3 variants were identified by sequencing, many were also seen in the 1000 genomes data, but 26 were novel. None of the variants identified by re-sequencing was in strong linkage disequilibrium (LD) with the associated markers. Imputation analysis refined association between ADAMTSL3 and schizophrenia, and highlighted additional common variants with similar levels of association. We evaluated the functional consequences of all variants identified by sequencing, or showing direct or imputed association. The strongest evidence for function remained with the originally associated variant, rs950169, suggesting that this variant may be causal of the association. Rare variants were also identified with possible functional impact. Our study confirms ADAMTSL3 as a candidate for further investigation in schizophrenia, using the variants identified here. The utility of imputation analysis is demonstrated, and we recommend wider use of this method to re-evaluate the existing canon of suggestive schizophrenia associations.
  • Drude, S. (2011). Nominalization and subordination in Awetí. Amerindia, 35, 189-218.

    Abstract

    This paper describes the different kinds of nominalizations and the main forms used in subordination in Awetí, a Tupian language spoken by ca. 150 people in central Bra-zil in the Upper Xingu area. Awetí does not belong to, but is arguably the closest rela-tive of the well-known Tupí-Guaraní subfamily, the largest branch of the Tupí stock. In our analysis, subordination in Awetí is achieved by means of forms which may have developed from nominalizations, but which are synchronously possibly best classified as verbal moods, belonging into the verbal paradigm. On the other hand, nouns (and in particular nouns derived from verbs) often appear as predicates, especially in equality and cleft sentences.
  • Drude, S. (2011). Word accent and its manifestation in Awetí. Amerindia, 35, 7-40.

    Abstract

    This paper describes the distribution and phonetic properties of accentuation of word forms in Awetí, a Tupian language spoken by ca. 150 people in central Brazil in the Upper Xingu area. Awetí does not belong to, but is arguably the closest relative of the better known Tupí-Guaraní subfamily, the largest branch of the Tupí stock. After a short overview over the word classes and general phonotactics of Awetí (sec-tion 2), we briefly discuss the notion ‘word accent’ and show that, in Awetí, it is generally located on the last syllable of the stem in morphologically simple forms (section 3). We then discuss regular and isolated exceptions to this rule (section 4). In section 5, we describe the distribution of the word accent when inflectional or deriva-tional suffixes are present – usually, the word accent of the word form with suffixes continues to be on the last syllable of the stem. After this descriptive part, we present a preliminary study of the acoustic-phonetic details of the manifestation of the word accent, observing word forms in isolation (section 6) and in different syntactic con-texts (section 7). The results are briefly summarized in the conclusion (section 8)
  • Duarri, A., Meng-Chin, A. L., Fokkens, M. R., Meijer, M., Smeets, C. J. L. M., Nibbeling, E. A. R., Boddeke, E., Sinke, R. J., Kampinga, H. H., Papazian, D. M., & Verbeek, D. S. (2015). Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner. Cellular and Molecular Life Sciences, 72(17), 3387-3399. doi:10.1007/s00018-015-1894-2.

    Abstract

    The dominantly inherited cerebellar ataxias are a heterogeneous group of neurodegenerative disorders caused by Purkinje cell loss in the cerebellum. Recently, we identified loss-of-function mutations in the KCND3 gene as the cause of spinocerebellar ataxia type 19/22 (SCA19/22), revealing a previously unknown role for the voltage-gated potassium channel, Kv4.3, in Purkinje cell survival. However, how mutant Kv4.3 affects wild-type Kv4.3 channel functioning remains unknown. We provide evidence that SCA19/22-mutant Kv4.3 exerts a dominant negative effect on the trafficking and surface expression of wild-type Kv4.3 in the absence of its regulatory subunit, KChIP2. Notably, this dominant negative effect can be rescued by the presence of KChIP2. We also found that all SCA19/22-mutant subunits either suppress wild-type Kv4.3 current amplitude or alter channel gating in a dominant manner. Our findings suggest that altered Kv4.3 channel localization and/or functioning resulting from SCA19/22 mutations may lead to Purkinje cell loss, neurodegeneration and ataxia.
  • Dufau, S., Duñabeitia, J. A., Moret-Tatay, C., McGonigal, A., Peeters, D., Alario, F.-X., Balota, D. A., Brysbaert, M., Carreiras, M., Ferrand, L., Ktori, M., Perea, M., Rastle, K., Sasburg, O., Yap, M. J., Ziegler, J. C., & Grainger, J. (2011). Smart phone, smart science: How the use of smartphones can revolutionize research in cognitive science. PLoS One, 6(9), e24974. doi:10.1371/journal.pone.0024974.

    Abstract

    Investigating human cognitive faculties such as language, attention, and memory most often relies on testing small and homogeneous groups of volunteers coming to research facilities where they are asked to participate in behavioral experiments. We show that this limitation and sampling bias can be overcome by using smartphone technology to collect data in cognitive science experiments from thousands of subjects from all over the world. This mass coordinated use of smartphones creates a novel and powerful scientific ‘‘instrument’’ that yields the data necessary to test universal theories of cognition. This increase in power represents a potential revolution in cognitive science
  • Duffield, N., Matsuo, A., & Roberts, L. (2007). Acceptable ungrammaticality in sentence matching. Second Language Research, 23(2), 155-177. doi:10.1177/0267658307076544.

    Abstract

    This paper presents results from a new set of experiments using the sentence matching paradigm (Forster, Kenneth (1979), Freedman & Forster (1985), also Bley-Vroman & Masterson (1989), investigating native-speakers’ and L2 learners’ knowledge of constraints on clitic placement in French.1 Our purpose is three-fold: (i) to shed more light on the contrasts between native-speakers and L2 learners observed in previous experiments, especially Duffield & White (1999), and Duffield, White, Bruhn de Garavito, Montrul & Prévost (2002); (ii), to address specific criticisms of the sentence-matching paradigm leveled by Gass (2001); (iii), to provide a firm empirical basis for follow-up experiments with L2 learners
  • Dunn, M., Foley, R., Levinson, S. C., Reesink, G., & Terrill, A. (2007). Statistical reasoning in the evaluation of typological diversity in Island Melanesia. Oceanic Linguistics, 46(2), 388-403.

    Abstract

    This paper builds on a previous work in which we attempted to retrieve a phylogenetic signal using abstract structural features alone, as opposed to cognate sets, drawn from a sample of Island Melanesian languages, both Oceanic (Austronesian) and (non-Austronesian) Papuan (Science 2005[309]: 2072-75 ). Here we clarify a number of misunderstandings of this approach, referring particularly to the critique by Mark Donohue and Simon Musgrave (in this same issue of Oceanic Linguistics), in which they fail to appreciate the statistical principles underlying computational phylogenetic methods. We also present new analyses that provide stronger evidence supporting the hypotheses put forward in our original paper: a reanalysis using Bayesian phylogenetic inference demonstrates the robustness of the data and methods, and provides a substantial improvement over the parsimony method used in our earlier paper. We further demonstrate, using the technique of spatial autocorrelation, that neither proximity nor Oceanic contact can be a major determinant of the pattern of structural variation of the Papuan languages, and thus that the phylogenetic relatedness of the Papuan languages remains a serious hypothesis.
  • Dunn, M., Burenhult, N., Kruspe, N., Tufvesson, S., & Becker, N. (2011). Aslian linguistic prehistory: A case study in computational phylogenetics. Diachronica, 28, 291-323. doi:10.1075/dia.28.3.01dun.

    Abstract

    This paper analyzes newly collected lexical data from 26 languages of the Aslian subgroup of the Austroasiatic language family using computational phylogenetic methods. We show the most likely topology of the Aslian family tree, discuss rooting and external relationships to other Austroasiatic languages, and investigate differences in the rates of diversification of different branches. Evidence is given supporting the classification of Jah Hut as a fourth top level subgroup of the family. The phylogenetic positions of known geographic and linguistic outlier languages are clarified, and the relationships of the little studied Aslian languages of Southern Thailand to the rest of the family are explored.
  • Dunn, M., Margetts, A., Meira, S., & Terrill, A. (2007). Four languages from the lower end of the typology of locative predication. Linguistics, 45, 873-892. doi:10.1515/LING.2007.026.

    Abstract

    As proposed by Ameka and Levinson (this issue) locative verb systems can be classified into four types according to the number of verbs distinguished. This article addresses the lower extreme of this typology: languages which offer no choice of verb in the basic locative function (BLF). These languages have either a single locative verb, or do not use verbs at all in the basic locative construction (BLC, the construction used to encode the BLF). A close analysis is presented of the behavior of BLF predicate types in four genetically diverse languages: Chukchi (Chukotko-Kamchatkan, Russian Arctic), and Lavukaleve (Papuan isolate, Solomon Islands), which have BLC with the normal copula/existential verb for the language; Tiriyó (Cariban/Taranoan, Brazil), which has an optional copula in the BLC; and Saliba (Austronesian/Western Oceanic, Papua New Guinea), a language with a verbless clause as the BLC. The status of these languages in the typology of positional verb systems is reviewed, and other relevant typological generalizations are discussed
  • Dunn, M., & Ross, M. (2007). Is Kazukuru really non-Austronesian? Oceanic Linguistics, 46(1), 210-231. doi:10.1353/ol.2007.0018.

    Abstract

    Kazukuru is an extinct language, originally spoken in the inland of the western part of the island of New Georgia, Solomon Islands, and attested by very limited historical sources. Kazukuru has generally been considered to be a Papuan, that is, non-Austronesian, language, mostly on the basis of its lexicon. Reevaluation of the available data suggests a high likelihood that Kazukuru was in fact an Oceanic Austronesian language. Pronominal paradigms are clearly of Austronesian origin, and many other aspects of language structured retrievable from the limited data are also congruent with regional Oceanic Austronesian typology. The extent and possible causes of Kazukuru lexical deviations from the Austronesian norm are evaluated and discussed.
  • Dunn, M., Greenhill, S. J., Levinson, S. C., & Gray, R. D. (2011). Evolved structure of language shows lineage-specific trends in word-order universals. Nature, 473, 79-82. doi:10.1038/nature09923.

    Abstract

    Languages vary widely but not without limit. The central goal of linguistics is to describe the diversity of human languages and explain the constraints on that diversity. Generative linguists following Chomsky have claimed that linguistic diversity must be constrained by innate parameters that are set as a child learns a language1, 2. In contrast, other linguists following Greenberg have claimed that there are statistical tendencies for co-occurrence of traits reflecting universal systems biases3, 4, 5, rather than absolute constraints or parametric variation. Here we use computational phylogenetic methods to address the nature of constraints on linguistic diversity in an evolutionary framework6. First, contrary to the generative account of parameter setting, we show that the evolution of only a few word-order features of languages are strongly correlated. Second, contrary to the Greenbergian generalizations, we show that most observed functional dependencies between traits are lineage-specific rather than universal tendencies. These findings support the view that—at least with respect to word order—cultural evolution is the primary factor that determines linguistic structure, with the current state of a linguistic system shaping and constraining future states.

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    Supplementary information
  • Dunn, M. (2000). Planning for failure: The niche of standard Chukchi. Current Issues in Language Planning, 1, 389-399. doi:10.1080/14664200008668013.

    Abstract

    This paper examines the effects of language standardization and orthography design on the Chukchi linguistic ecology. The process of standardisation has not taken into consideration the gender-based sociolects of colloquial Chukchi and is based on a grammaticaldescriptionwhich does not reflectactual Chukchi use; as a result standard Chukchi has not gained a place in the Chukchi language ecology. The Cyrillic orthography developed for Chukchi is also problematic as it is based on features of Russian phonology, rather than on Chukchi itself: this has meant that a knowledge of written Chukchi is dependent on a knowledge of the principles of Russian orthography. The aspects of language planning have had a large impact on the pre-existing Chukchi language ecology which has contributed to the obsolescence of the colloquial language.
  • Ebisch, S. J., Gallese, V., Willems, R. M., Mantini, D., Groen, W. B., Romani, G. L., Buitelaar, J. K., & Bekkering, H. (2011). Altered intrinsic functional connectivity of anterior and posterior insular regions in high-functioning participants with autism spectrum disorder. Human Brain Mapping, 32, 1013-1028. doi:10.1002/hbm.21085.

    Abstract

    Impaired understanding of others' sensations and emotions as well as abnormal experience of their own emotions and sensations is frequently reported in individuals with Autism Spectrum Disorder (ASD). It is hypothesized that these abnormalities are based on altered connectivity within “shared” neural networks involved in emotional awareness of self and others. The insula is considered a central brain region in a network underlying these functions, being located at the transition of information about bodily arousal and the physiological state of the body to subjective feelings. The present study investigated the intrinsic functional connectivity properties of the insula in 14 high-functioning participants with ASD (HF-ASD) and 15 typically developing (TD) participants in the age range between 12 and 20 years by means of “resting state” or “nontask” functional magnetic resonance imaging. Essentially, a distinction was made between anterior and posterior regions of the insular cortex. The results show a reduced functional connectivity in the HF-ASD group, compared with the TD group, between anterior as well as posterior insula and specific brain regions involved in emotional and sensory processing. It is suggested that functional abnormalities in a network involved in emotional and interoceptive awareness might be at the basis of altered emotional experiences and impaired social abilities in ASD, and that these abnormalities are partly based on the intrinsic functional connectivity properties of such a network.
  • Edlinger, G., Bastiaansen, M. C. M., Brunia, C., Neuper, C., & Pfurtscheller, G. (1999). Cortical oscillatory activity assessed by combined EEG and MEG recordings and high resolution ERD methods. Biomedizinische Technik, 44(2), 131-134.
  • Eerland, A., Guadalupe, T. M., & Zwaan, R. A. (2011). Leaning to the left makes the Eiffel Tower seem smaller: Posture-modulated estimation. Psychological Science, 22, 1511-1514. doi:10.1177/0956797611420731.

    Abstract

    In two experiments, we investigated whether body posture influences people’s estimation of quantities. According to the mental-number-line theory, people mentally represent numbers along a line with smaller numbers on the left and larger numbers on the right. We hypothesized that surreptitiously making people lean to the right or to the left would affect their quantitative estimates. Participants answered estimation questions while standing on a Wii Balance Board. Posture was manipulated within subjects so that participants answered some questions while they leaned slightly to the left, some questions while they leaned slightly to the right, and some questions while they stood upright. Crucially, participants were not aware of this manipulation. Estimates were significantly smaller when participants leaned to the left than when they leaned to the right.

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  • Enfield, N. J., Kita, S., & De Ruiter, J. P. (2007). Primary and secondary pragmatic functions of pointing gestures. Journal of Pragmatics, 39(10), 1722-1741. doi:10.1016/j.pragma.2007.03.001.

    Abstract

    This article presents a study of a set of pointing gestures produced together with speech in a corpus of video-recorded “locality description” interviews in rural Laos. In a restricted set of the observed gestures (we did not consider gestures with special hand shapes, gestures with arc/tracing motion, or gestures directed at referents within physical reach), two basic formal types of pointing gesture are observed: B-points (large movement, full arm, eye gaze often aligned) and S-points (small movement, hand only, casual articulation). Taking the approach that speech and gesture are structurally integrated in composite utterances, we observe that these types of pointing gesture have distinct pragmatic functions at the utterance level. One type of gesture (usually “big” in form) carries primary, informationally foregrounded information (for saying “where” or “which one”). Infants perform this type of gesture long before they can talk. The second type of gesture (usually “small” in form) carries secondary, informationally backgrounded information which responds to a possible but uncertain lack of referential common ground. We propose that the packaging of the extra locational information into a casual gesture is a way of adding extra information to an utterance without it being on-record that the added information was necessary. This is motivated by the conflict between two general imperatives of communication in social interaction: a social-affiliational imperative not to provide more information than necessary (“Don’t over-tell”), and an informational imperative not to provide less information than necessary (“Don’t under-tell”).
  • Enfield, N. J. (2011). Books that live and die [Book review]. Current Anthropology, 52(1), 129-131. doi:10.1086/657928.

    Abstract

    Reviewed work(s): Dying Words: Endangered Languages and What They Have to Tell Us. By Nicholas Evans. Indianapolis: Wiley-Blackwell, 2010. On the Death and Life of Languages. By Claude Hagège, translated by Jody Gladding. New Haven, CT: Yale University Press, 2009.
  • Enfield, N. J. (2011). Credit tests [Review of the book You are not a gadget by Jaron Lanier]. The Times Literary Supplement, February 18, 2011, 12.
  • Enfield, N. J. (2007). Encoding three-participant events in the Lao clause. Linguistics, 45(3), 509-538. doi:10.1515/LING.2007.016.

    Abstract

    Any language will have a range of predicates that specify three core participants (e.g. 'put', 'show', 'give'), and will conventionally provide a range of constructional types for the expression of these three participants in a structured single-clause or single-sentence event description. This article examines the clausal encoding of three-participant events in Lao, a Tai language of Southeast Asia. There is no possibility in Lao for expression of three full arguments in the core of a single-verb clause (although it is possible to have a third argument in a noncore slot, marked as oblique with a prepositionlike element). Available alternatives include extraposing an argument using a topic-comment construction, incorporating an argument into the verb phrase, and ellipsing one or more contextually retrievable arguments. A more common strategy is verb serialization, for example, where a threeplace verb (e.g. 'put') is assisted by an additional verb (typically a verb of handling such as 'carry') that provides a slot for the theme argument (e.g. the transferred object in a putting scene). The event construal encoded by this type of structure decomposes the event into a first stage in which the agent comes into control over a theme, and a second in which the agent performs a controlled action (e.g. of transfer) with respect to that theme and a goal (and/or source). The particular set of strategies that Lao offers for encoding three-participant events — notably, topic-comment strategy, ellipsis strategy, serial verb strategy — conform with (and are presumably motivated by) the general typological profile of the language. The typological features of Lao are typical for the mainland Southeast Asia area (isolating, topic-prominent, verb-serializing, widespread nominal ellipsis).
  • Enfield, N. J. (2007). [Comment on 'Agency' by Paul Kockelman]. Current Anthropology, 48(3), 392-392. doi:10.1086/512998.
  • Enfield, N. J. (2007). [review of the book Ethnopragmatics: Understanding discourse in cultural context ed. by Cliff Goddard]. Intercultural Pragmatics, 4(3), 419-433. doi:10.1515/IP.2007.021.
  • Enfield, N. J. (2007). Lao separation verbs and the logic of linguistic event categorization. Cognitive Linguistics, 18(2), 287-296. doi:10.1515/COG.2007.016.

    Abstract

    While there are infinite conceivable events of material separation, those actually encoded in the conventions of a given language's verb semantics number only a few. Furthermore, there appear to be crosslinguistic parallels in the native verbal analysis of this conceptual domain. What are the operative distinctions, and why these? This article analyses a key subset of the bivalent (transitive) verbs of cutting and breaking in Lao. I present a decompositional analysis of the verbs glossed 'cut (off)', 'cut.into.with.placed.blade', 'cut.into.with.moving.blade', and 'snap', pursuing the idea that the attested combinations of sub-events have a natural logic to them. Consideration of the nature of linguistic categories, as distinct from categories in general, suggests that the attested distinctions must have ethnographic and social interactional significance, raising new lines of research for cognitive semantics.
  • Enfield, N. J. (2011). Hidden delights [Review of the book How pleasure works by Paul Bloom]. The Times Literary Supplement, January 21, 2011, 30-30.
  • Enfield, N. J. (2015). Linguistic relativity from reference to agency. Annual Review of Anthropology, 44, 207-224. doi:10.1146/annurev-anthro-102214-014053.

    Abstract

    How are language, thought, and reality related? Interdisciplinary research on this question over the past two decades has made significant progress. Most of the work has been Neo-Whorfian in two senses: One, it has been driven by research questions that were articulated most explicitly and most famously by the linguistic anthropologist Benjamin Lee Whorf, and two, it has limited the scope of inquiry to Whorf's narrow interpretations of the key terms “language,” “thought,” and “reality.” This article first reviews some of the ideas and results of Neo-Whorfian work, concentrating on the special role of linguistic categorization in heuristic decision making. It then considers new and potential directions in work on linguistic relativity, taken broadly to mean the ways in which the perspective offered by a given language can affect thought (or mind) and reality. New lines of work must reconsider the idea of linguistic relativity by exploring the range of available interpretations of the key terms: in particular, “language” beyond reference, “thought” beyond nonsocial processing, and “reality” beyond brute, nonsocial facts.
  • Enfield, N. J. (1999). On the indispensability of semantics: Defining the ‘vacuous’. Rask: internationalt tidsskrift for sprog og kommunikation, 9/10, 285-304.
  • Enfield, N. J. (2015). Other-initiated repair in Lao. Open linguistics, 1(1), 119-144. doi:10.2478/opli-2014-0006.

    Abstract

    This article describes the interactional patterns and linguistic structures associated with otherinitiated repair, as observed in a corpus of video-recorded conversation in the Lao language (a Southwestern Tai language spoken in Laos, Thailand, and Cambodia). The article reports findings specific to the Lao language from the comparative project that is the topic of this special issue. While the scope is general to the overall pattern of other-initiated repair as a set of practices and a system of semiotic resources, special attention is given to (1) the range of repair operations that are elicited by open other-initiators of repair in Lao, especially the subtle changes made when problem turns are repeated, and (2) the use of phrase-final particles—a characteristic feature of Lao grammar—in the marking of both other-initiations of repair and repair solution turns
  • Enfield, N. J. (2011). Taste in two tongues: A Southeast Asian study of semantic convergence. The Senses & Society, 6(1), 30-37. doi:10.2752/174589311X12893982233632.

    Abstract

    This article examines vocabulary for taste and flavor in two neighboring but unrelated languages (Lao and Kri) spoken in Laos, Southeast Asia. There are very close similarities in underlying semantic distinctions made in the taste/flavor domain in these two languages, not just in the set of basic tastes distinguished (sweet, salty, bitter, sour, umami or glutamate), but in a series of further basic terms for flavors, specifying texture and other sensations in the mouth apart from pure taste (e.g. starchy, dry in the mouth, minty, tingly, spicy). After presenting sets of taste/flavor vocabulary in the two languages and showing their high degree of convergence, the article discusses some methodological and theoretical issues that arise from the observation of close convergence in semantic structure across languages, in particular the issue of how much inter-speaker variation is possible not only across apparently highly convergent systems, but also within languages. The final section raises possible causes for the close convergence of semantic structure in the two languages. The conclusion is that the likely cause of this convergence is historical social contact between speech communities in the area, although the precise mode of influence (e.g. direction of transmission) is unknown.
  • Enfield, N. J. (2000). The theory of cultural logic: How individuals combine social intelligence with semiotics to create and maintain cultural meaning. Cultural Dynamics, 12(1), 35-64. doi:10.1177/092137400001200102.

    Abstract

    The social world is an ecological complex in which cultural meanings and knowledges (linguistic and non-linguistic) personally embodied by individuals are intercalibrated via common attention to commonly accessible semiotic structures. This interpersonal ecology bridges realms which are the subject matter of both anthropology and linguistics, allowing the public maintenance of a system of assumptions and counter-assumptions among individuals as to what is mutually known (about), in general and/or in any particular context. The mutual assumption of particular cultural ideas provides human groups with common premises for predictably convergent inferential processes. This process of people collectively using effectively identical assumptions in interpreting each other's actions—i.e. hypothesizing as to each other's motivations and intentions—may be termed cultural logic. This logic relies on the establishment of stereotypes and other kinds of precedents, catalogued in individuals’ personal libraries, as models and scenarios which may serve as reference in inferring and attributing motivations behind people's actions, and behind other mysterious phenomena. This process of establishing conceptual convention depends directly on semiotics, since groups of individuals rely on external signs as material for common focus and, thereby, agreement. Social intelligence binds signs in the world (e.g. speech sounds impressing upon eardrums), with individually embodied representations (e.g. word meanings and contextual schemas). The innate tendency for people to model the intentions of others provides an ultimately biological account for the logic behind culture. Ethnographic examples are drawn from Laos and Australia.
  • Erard, M. (2015). What's in a name? Science, 347(6225), 941-943. doi:10.1126/science.347.6225.941.
  • Ernestus, M., Van Mulken, M., & Baayen, R. H. (2007). Ridders en heiligen in tijd en ruimte: Moderne stylometrische technieken toegepast op Oud-Franse teksten. Taal en Tongval, 58, 1-83.

    Abstract

    This article shows that Old-French literary texts differ systematically in their relative frequencies of syntactic constructions. These frequencies reflect differences in register (poetry versus prose), region (Picardy, Champagne, and Esatern France), time period (until 1250, 1251 – 1300, 1301 – 1350), and genre (hagiography, romance of chivalry, or other).
  • Ernestus, M., & Baayen, R. H. (2007). Paradigmatic effects in auditory word recognition: The case of alternating voice in Dutch. Language and Cognitive Processes, 22(1), 1-24. doi:10.1080/01690960500268303.

    Abstract

    Two lexical decision experiments addressed the role of paradigmatic effects in auditory word recognition. Experiment 1 showed that listeners classified a form with an incorrectly voiced final obstruent more readily as a word if the obstruent is realised as voiced in other forms of that word's morphological paradigm. Moreover, if such was the case, the exact probability of paradigmatic voicing emerged as a significant predictor of the response latencies. A greater probability of voicing correlated with longer response latencies for words correctly realised with voiceless final obstruents. A similar effect of this probability was observed in Experiment 2 for words with completely voiceless or weakly voiced (incompletely neutralised) final obstruents. These data demonstrate the relevance of paradigmatically related complex words for the processing of morphologically simple words in auditory word recognition.

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