Publications

Displaying 101 - 200 of 383
  • Fisher, S. E., Marlow, A. J., Lamb, J., Maestrini, E., Williams, D. F., Richardson, A. J., Weeks, D. E., Stein, J. F., & Monaco, A. P. (1999). A quantitative-trait locus on chromosome 6p influences different aspects of developmental dyslexia. American Journal of Human Genetics, 64(1), 146-156. doi:10.1086/302190.

    Abstract

    Recent application of nonparametric-linkage analysis to reading disability has implicated a putative quantitative-trait locus (QTL) on the short arm of chromosome 6. In the present study, we use QTL methods to evaluate linkage to the 6p25-21.3 region in a sample of 181 sib pairs from 82 nuclear families that were selected on the basis of a dyslexic proband. We have assessed linkage directly for several quantitative measures that should correlate with different components of the phenotype, rather than using a single composite measure or employing categorical definitions of subtypes. Our measures include the traditional IQ/reading discrepancy score, as well as tests of word recognition, irregular-word reading, and nonword reading. Pointwise analysis by means of sib-pair trait differences suggests the presence, in 6p21.3, of a QTL influencing multiple components of dyslexia, in particular the reading of irregular words (P=.0016) and nonwords (P=.0024). A complementary statistical approach involving estimation of variance components supports these findings (irregular words, P=.007; nonwords, P=.0004). Multipoint analyses place the QTL within the D6S422-D6S291 interval, with a peak around markers D6S276 and D6S105 consistently identified by approaches based on trait differences (irregular words, P=.00035; nonwords, P=.0035) and variance components (irregular words, P=.007; nonwords, P=.0038). Our findings indicate that the QTL affects both phonological and orthographic skills and is not specific to phoneme awareness, as has been previously suggested. Further studies will be necessary to obtain a more precise localization of this QTL, which may lead to the isolation of one of the genes involved in developmental dyslexia.
  • Fisher, S. E., & DeFries, J. C. (2002). Developmental dyslexia: Genetic dissection of a complex cognitive trait. Nature Reviews Neuroscience, 3, 767-780. doi:10.1038/nrn936.

    Abstract

    Developmental dyslexia, a specific impairment of reading ability despite adequate intelligence and educational opportunity, is one of the most frequent childhood disorders. Since the first documented cases at the beginning of the last century, it has become increasingly apparent that the reading problems of people with dyslexia form part of a heritable neurobiological syndrome. As for most cognitive and behavioural traits, phenotypic definition is fraught with difficulties and the genetic basis is complex, making the isolation of genetic risk factors a formidable challenge. Against such a background, it is notable that several recent studies have reported the localization of genes that influence dyslexia and other language-related traits. These investigations exploit novel research approaches that are relevant to many areas of human neurogenetics.
  • Fisher, S. E., Francks, C., Marlow, A. J., MacPhie, I. L., Newbury, D. F., Cardon, L. R., Ishikawa-Brush, Y., Richardson, A. J., Talcott, J. B., Gayán, J., Olson, R. K., Pennington, B. F., Smith, S. D., DeFries, J. C., Stein, J. F., & Monaco, A. P. (2002). Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia. Nature Genetics, 30(1), 86-91. doi:10.1038/ng792.

    Abstract

    Developmental dyslexia is defined as a specific and significant impairment in reading ability that cannot be explained by deficits in intelligence, learning opportunity, motivation or sensory acuity. It is one of the most frequently diagnosed disorders in childhood, representing a major educational and social problem. It is well established that dyslexia is a significantly heritable trait with a neurobiological basis. The etiological mechanisms remain elusive, however, despite being the focus of intensive multidisciplinary research. All attempts to map quantitative-trait loci (QTLs) influencing dyslexia susceptibility have targeted specific chromosomal regions, so that inferences regarding genetic etiology have been made on the basis of very limited information. Here we present the first two complete QTL-based genome-wide scans for this trait, in large samples of families from the United Kingdom and United States. Using single-point analysis, linkage to marker D18S53 was independently identified as being one of the most significant results of the genome in each scan (P< or =0.0004 for single word-reading ability in each family sample). Multipoint analysis gave increased evidence of 18p11.2 linkage for single-word reading, yielding top empirical P values of 0.00001 (UK) and 0.0004 (US). Measures related to phonological and orthographic processing also showed linkage at this locus. We replicated linkage to 18p11.2 in a third independent sample of families (from the UK), in which the strongest evidence came from a phoneme-awareness measure (most significant P value=0.00004). A combined analysis of all UK families confirmed that this newly discovered 18p QTL is probably a general risk factor for dyslexia, influencing several reading-related processes. This is the first report of QTL-based genome-wide scanning for a human cognitive trait.
  • Fisher, S. E., Black, G. C. M., Lloyd, S. E., Wrong, O. M., Thakker, R. V., & Craig, I. W. (1994). Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis). Human Molecular Genetics, 3, 2053-2059.

    Abstract

    Dent's disease, an X-linked renal tubular disorder, is a form of Fanconi syndrome which is characterized by proteinuria, hypercalciuria, nephrocalcinosis, kidney stones and renal failure. Previous studies localised the gene responsible to Xp11.22, within a microdeletion involving the hypervariable locus DXS255. Further analysis using new probes which flank this locus indicate that the deletion is less than 515 kb. A 185 kb YAC containing DXS255 was used to screen a cDNA library from adult kidney in order to isolate coding sequences falling within the deleted region which may be implicated in the disease aetiology. We identified two clones which are evolutionarily conserved, and detect a 9.5 kb transcript which is expressed predominantly in the kidney. Sequence analysis of 780 bp of ORF from the clones suggests that the identified gene, termed hCIC-K2, encodes a new member of the CIC family of voltage-gated chloride channels. Genomic fragments detected by the cDNA clones are completely absent in patients who have an associated microdeletion. On the basis of the expression pattern, proposed function and deletion mapping, hCIC-K2 is a strong candidate for Dent's disease.
  • Francks, C., Fisher, S. E., MacPhie, I. L., Richardson, A. J., Marlow, A. J., Stein, J. F., & Monaco, A. P. (2002). A genomewide linkage screen for relative hand skill in sibling pairs. American Journal of Human Genetics, 70(3), 800-805. doi:10.1086/339249.

    Abstract

    Genomewide quantitative-trait locus (QTL) linkage analysis was performed using a continuous measure of relative hand skill (PegQ) in a sample of 195 reading-disabled sibling pairs from the United Kingdom. This was the first genomewide screen for any measure related to handedness. The mean PegQ in the sample was equivalent to that of normative data, and PegQ was not correlated with tests of reading ability (correlations between −0.13 and 0.05). Relative hand skill could therefore be considered normal within the sample. A QTL on chromosome 2p11.2-12 yielded strong evidence for linkage to PegQ (empirical P=.00007), and another suggestive QTL on 17p11-q23 was also identified (empirical P=.002). The 2p11.2-12 locus was further analyzed in an independent sample of 143 reading-disabled sibling pairs, and this analysis yielded an empirical P=.13. Relative hand skill therefore is probably a complex multifactorial phenotype with a heterogeneous background, but nevertheless is amenable to QTL-based gene-mapping approaches.
  • Francks, C., Fisher, S. E., Olson, R. K., Pennington, B. F., Smith, S. D., DeFries, J. C., & Monaco, A. P. (2002). Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus: Quantitative association analysis and positional candidate genes SEMA4F and OTX1. Psychiatric Genetics, 12(1), 35-41.

    Abstract

    A locus on chromosome 2p12-16 has been implicated in dyslexia susceptibility by two independent linkage studies, including our own study of 119 nuclear twin-based families, each with at least one reading-disabled child. Nonetheless, no variant of any gene has been reported to show association with dyslexia, and no consistent clinical evidence exists to identify candidate genes with any strong a priori logic. We used 21 microsatellite markers spanning 2p12-16 to refine our 1-LOD unit linkage support interval to 12cM between D2S337 and D2S286. Then, in quantitative association analysis, two microsatellites yielded P values<0.05 across a range of reading-related measures (D2S2378 and D2S2114). The exon/intron borders of two positional candidate genes within the region were characterized, and the exons were screened for polymorphisms. The genes were Semaphorin4F (SEMA4F), which encodes a protein involved in axonal growth cone guidance, and OTX1, encoding a homeodomain transcription factor involved in forebrain development. Two non-synonymous single nucleotide polymorphisms were found in SEMA4F, each with a heterozygosity of 0.03. One intronic single nucleotide polymorphism between exons 12 and 13 of SEMA4F was tested for quantitative association, but no significant association was found. Only one single nucleotide polymorphism was found in OTX1, which was exonic but silent. Our data therefore suggest that linkage with reading disability at 2p12-16 is not caused by coding variants of SEMA4F or OTX1. Our study outlines the approach necessary for the identification of genetic variants causing dyslexia susceptibility in an epidemiological population of dyslexics.
  • Francks, C., MacPhie, I. L., & Monaco, A. P. (2002). The genetic basis of dyslexia. The Lancet Neurology, 1(8), 483-490. doi:10.1016/S1474-4422(02)00221-1.

    Abstract

    Dyslexia, a disorder of reading and spelling, is a heterogeneous neurological syndrome with a complex genetic and environmental aetiology. People with dyslexia differ in their individual profiles across a range of cognitive, physiological, and behavioural measures related to reading disability. Some or all of the subtypes of dyslexia might have partly or wholly distinct genetic causes. An understanding of the role of genetics in dyslexia could help to diagnose and treat susceptible children more effectively and rapidly than is currently possible and in ways that account for their individual disabilities. This knowledge will also give new insights into the neurobiology of reading and language cognition. Genetic linkage analysis has identified regions of the genome that might harbour inherited variants that cause reading disability. In particular, loci on chromosomes 6 and 18 have shown strong and replicable effects on reading abilities. These genomic regions contain tens or hundreds of candidate genes, and studies aimed at the identification of the specific causal genetic variants are underway.
  • Fransson, P., Merboldt, K.-D., Petersson, K. M., Ingvar, M., & Frahm, J. (2002). On the effects of spatial filtering — A comparative fMRI study of episodic memory encoding at high and low resolution. NeuroImage, 16(4), 977-984. doi:10.1006/nimg.2002.1079.

    Abstract

    Theeffects of spatial filtering in functional magnetic resonance imaging were investigated by reevaluating the data of a previous study of episodic memory encoding at 2 × 2 × 4-mm3 resolution with use of a SPM99 analysis involving a Gaussian kernel of 8-mm full width at half maximum. In addition, a multisubject analysis of activated regions was performed by normalizing the functional images to an approximate Talairach brain atlas. In individual subjects, spatial filtering merged activations in anatomically separated brain regions. Moreover, small foci of activated pixels which originated from veins became blurred and hence indistinguishable from parenchymal responses. The multisubject analysis resulted in activation of the hippocampus proper, a finding which could not be confirmed by the activation maps obtained at high resolution. It is concluded that the validity of multisubject fMRI analyses can be considerably improved by first analyzing individual data sets at optimum resolution to assess the effects of spatial filtering and minimize the risk of signal contamination by macroscopically visible vessels.
  • Guirardello-Damian, R., & Skiba, R. (2002). Trumai Corpus: An example of presenting multi-media data in the IMDI-browser. In P. Austin, H. Dry, & P. Wittenburg (Eds.), Proceedings of the international LREC workshop on resources and tools in field linguistics (pp. 16-1-16-8). Paris: European Language Resources Association.

    Abstract

    Trumai, a genetically isolated language spoken in Brazil (Xingu reserve), is an example of an endangered language. Although the Trumai population consists of more than 100 individuals, only 51 people speak the language. The oral traditions are progressively dying. Given the current scenario, the documentation of this language and its cultural aspects is of great importance. In the framework of the DoBeS program (Documentation of Endangered Languages), the project "Documentation of Trumai" has selected and organized a collection of Trumai texts, with a multi-media representation of the corpus. Several kinds of information and data types are being included in the archive of the language: texts with audio and video recordings; written texts from educational materials; drawings; photos; songs; annotations in different formats; lexicon; field notes; results from scientific studies of the language (sound system, sketch grammar, comparative studies with other Xinguan languages), etc. All materials are integrated into the IMDI-Browser, a specialized tool for presenting and searching for linguistic data. This paper explores the processing phases and the results of the Trumai project taking into consideration the issue of how to combine the needs and wishes of field linguistics (content and research aspects) and the needs of archiving (structure and workflow aspects) in a well-organized corpus.
  • Gullberg, M., & Holmqvist, K. (1999). Keeping an eye on gestures: Visual perception of gestures in face-to-face communication. Pragmatics & Cognition, 7(1), 35-63. doi:10.1075/pc.7.1.04gul.

    Abstract

    Since listeners usually look at the speaker's face, gestural information has to be absorbed through peripheral visual perception. In the literature, it has been suggested that listeners look at gestures under certain circumstances: 1) when the articulation of the gesture is peripheral; 2) when the speech channel is insufficient for comprehension; and 3) when the speaker him- or herself indicates that the gesture is worthy of attention. The research here reported employs eye tracking techniques to study the perception of gestures in face-to-face interaction. The improved control over the listener's visual channel allows us to test the validity of the above claims. We present preliminary findings substantiating claims 1 and 3, and relate them to theoretical proposals in the literature and to the issue of how visual and cognitive attention are related.
  • Gulrajani, G., & Harrison, D. (2002). SHAWEL: Sharable and interactive web-lexicons. In P. Austin, H. Dry, & P. Wittenburg (Eds.), Proceedings of the international LREC workshop on resources and tools in field linguistics (pp. 9-1-9-4). Paris: European Language Resources Association.

    Abstract

    A prototypical lexicon tool was implemented which was intended to allow researchers to collaboratively create lexicons of endangered languages. Increasingly often researchers documenting or analyzing a language work at different locations. Lexicons that evolve through continuous interaction between the collaborators can only be efficiently produced when it can be accessed and manipulated via the Internet. The SHAWEL tool was developed to address these needs; it makes use of a thin Java client and a central database solution.
  • Gumperz, J. J., & Levinson, S. C. (1991). Rethinking linguistic relativity. Current Anthropology, 32(5), 613-623. Retrieved from http://www.jstor.org/stable/2743696.
  • Hagoort, P. (1994). Afasie als een tekort aan tijd voor spreken en verstaan. De Psycholoog, 4, 153-154.
  • Hagoort, P. (1999). De toekomstige eeuw zonder psychologie. Psychologie Magazine, 18, 35-36.
  • Hagoort, P. (2002). De koninklijke verloving tussen psychologie en neurowetenschap. De Psycholoog, 37, 107-113.
  • Hagoort, P., & Brown, C. M. (1999). Gender electrified: ERP evidence on the syntactic nature of gender processing. Journal of Psycholinguistic Research, 28(6), 715-728. doi:10.1023/A:1023277213129.

    Abstract

    The central issue of this study concerns the claim that the processing of gender agreement in online sentence comprehension is a syntactic rather than a conceptual/semantic process. This claim was tested for the grammatical gender agreement in Dutch between the definite article and the noun. Subjects read sentences in which the definite article and the noun had the same gender and sentences in which the gender agreement was violated, While subjects read these sentences, their electrophysiological activity was recorded via electrodes placed on the scalp. Earlier research has shown that semantic and syntactic processing events manifest themselves in different event-related brain potential (ERP) effects. Semantic integration modulates the amplitude of the so-called N400.The P600/SPS is an ERP effect that is more sensitive to syntactic processes. The violation of grammatical gender agreement was found to result in a P600/SPS. For violations in sentence-final position, an additional increase of the N400 amplitude was observed. This N400 effect is interpreted as resulting from the consequence of a syntactic violation for the sentence-final wrap-up. The overall pattern of results supports the claim that the on-line processing of gender agreement information is not a content driven but a syntactic-form driven process.
  • Hagoort, P. (1994). Het brein op een kier: Over hersenen gesproken. Psychologie, 13, 42-46.
  • Hagoort, P., & Brown, C. M. (1999). The consequences of the temporal interaction between syntactic and semantic processes for haemodynamic studies of language. NeuroImage, 9, S1024-S1024.
  • Hagoort, P., Ramsey, N., Rutten, G.-J., & Van Rijen, P. (1999). The role of the left anterior temporal cortex in language processing. Brain and Language, 69, 322-325. doi:10.1006/brln.1999.2169.
  • Hagoort, P., Indefrey, P., Brown, C. M., Herzog, H., Steinmetz, H., & Seitz, R. J. (1999). The neural circuitry involved in the reading of german words and pseudowords: A PET study. Journal of Cognitive Neuroscience, 11(4), 383-398. doi:10.1162/089892999563490.

    Abstract

    Silent reading and reading aloud of German words and pseudowords were used in a PET study using (15O)butanol to examine the neural correlates of reading and of the phonological conversion of legal letter strings, with or without meaning.
    The results of 11 healthy, right-handed volunteers in the age range of 25 to 30 years showed activation of the lingual gyri during silent reading in comparison with viewing a fixation cross. Comparisons between the reading of words and pseudowords suggest the involvement of the middle temporal gyri in retrieving both the phonological and semantic code for words. The reading of pseudowords activates the left inferior frontal gyrus, including the ventral part of Broca’s area, to a larger extent than the reading of words. This suggests that this area might be involved in the sublexical conversion of orthographic input strings into phonological output codes. (Pre)motor areas were found to be activated during both silent reading and reading aloud. On the basis of the obtained activation patterns, it is hypothesized that the articulation of high-frequency syllables requires the retrieval of their concomitant articulatory gestures from the SMA and that the articulation of lowfrequency syllables recruits the left medial premotor cortex.
  • Harbusch, K., & Kempen, G. (2002). A quantitative model of word order and movement in English, Dutch and German complement constructions. In Proceedings of the 19th international conference on Computational linguistics. San Francisco: Morgan Kaufmann.

    Abstract

    We present a quantitative model of word order and movement constraints that enables a simple and uniform treatment of a seemingly heterogeneous collection of linear order phenomena in English, Dutch and German complement constructions (Wh-extraction, clause union, extraposition, verb clustering, particle movement, etc.). Underlying the scheme are central assumptions of the psycholinguistically motivated Performance Grammar (PG). Here we describe this formalism in declarative terms based on typed feature unification. PG allows a homogenous treatment of both the within- and between-language variations of the ordering phenomena under discussion, which reduce to different settings of a small number of quantitative parameters.
  • Härle, M., Dobel, C., Cohen, R., & Rockstroh, B. (2002). Brain activity during syntactic and semantic processing - a magnetoencephalographic study. Brain Topography, 15(1), 3-11. doi:10.1023/A:1020070521429.

    Abstract

    Drawings of objects were presented in series of 54 each to 14 German speaking subjects with the tasks to indicate by button presses a) whether the grammatical gender of an object name was masculine ("der") or feminine ("die") and b) whether the depicted object was man-made or nature-made. The magnetoencephalogram (MEG) was recorded with a whole-head neuromagnetometer and task-specific patterns of brain activity were determined in the source space (Minimum Norm Estimates, MNE). A left-temporal focus of activity 150-275 ms after stimulus onset in the gender decision compared to the semantic classification task was discussed as indicating the retrieval of syntactic information, while a more expanded left hemispheric activity in the gender relative to the semantic task 300-625 ms after stimulus onset was discussed as indicating phonological encoding. A predominance of activity in the semantic task was observed over right fronto-central region 150-225 ms after stimulus-onset, suggesting that semantic and syntactic processes are prominent in this stage of lexical selection.
  • Heritage, J., & Stivers, T. (1999). Online commentary in acute medical visits: A method of shaping patient expectations. Social Science and Medicine, 49(11), 1501-1517. doi:10.1016/S0277-9536(99)00219-1.
  • Hoeks, J. C. J., Vonk, W., & Schriefers, H. (2002). Processing coordinated structures in context: The effect of topic-structure on ambiguity resolution. Journal of Memory and Language, 46(1), 99-119. doi:10.1006/jmla.2001.2800.

    Abstract

    When a sentence such as The model embraced the designer and the photographer laughed is read, the noun phrase the photographer is temporarily ambiguous: It can be either one of the objects of embraced (NP-coordination) or the subject of a new, conjoined sentence (S-coordination). It has been shown for a number of languages, including Dutch (the language used in this study), that readers prefer NP-coordination over S-coordination, at least in isolated sentences. In the present paper, it will be suggested that NP-coordination is preferred because it is the simpler of the two options in terms of topic-structure; in NP-coordinations there is only one topic, whereas S-coordinations contain two. Results from off-line (sentence completion) and online studies (a self-paced reading and an eye tracking experiment) support this topic-structure explanation. The processing difficulty associated with S-coordinated sentences disappeared when these sentences followed contexts favoring a two-topic continuation. This finding establishes topic-structure as an important factor in online sentence processing.
  • Holler, J., & Beattie, G. (2002). A micro-analytic investigation of how iconic gestures and speech represent core semantic features in talk. Semiotica, 142, 31-69.
  • Indefrey, P., & Levelt, W. J. M. (1999). A meta-analysis of neuroimaging experiments on word production. Neuroimage, 7, 1028.
  • Indefrey, P. (1999). Some problems with the lexical status of nondefault inflection. Behavioral and Brain Sciences, 22(6), 1025. doi:10.1017/S0140525X99342229.

    Abstract

    Clahsen's characterization of nondefault inflection as based exclusively on lexical entries does not capture the full range of empirical data on German inflection. In the verb system differential effects of lexical frequency seem to be input-related rather than affecting morphological production. In the noun system, the generalization properties of -n and -e plurals exceed mere analogy-based productivity.
  • Janse, E., & Quené, H. (1999). On the suitability of the cross-modal semantic priming task. In Proceedings of the XIVth International Congress of Phonetic Sciences (pp. 1937-1940).
  • Janse, E. (2002). Time-compressing natural and synthetic speech. In Proceedings of 7th International Conference on Spoken Language Processing (pp. 1645-1648).
  • Janssen, D. P., Roelofs, A., & Levelt, W. J. M. (2002). Inflectional frames in language production. Language and Cognitive Processes, 17(3), 209-236. doi:10.1006/jmla.2001.2800.

    Abstract

    The authors report six implicit priming experiments that examined the production of inflected forms. Participants produced words out of small sets in response to prompts. The words differed in form or shared word-initial segments, which allowed for preparation. In constant inflectional sets, the words had the same number of inflectional suffixes, whereas in variable sets the number of suffixes differed. In the experiments, preparation effects were obtained, which were larger in the constant than in the variable sets. Control experiments showed that this difference in effect was not due to syntactic class or phonological form per se. The results are interpreted in terms of a slot-and-filler model of word production, in which inflectional frames, on the one hand, and stems and affixes, on the other hand, are independently spelled out on the basis of an abstract morpho-syntactic specification of the word, which is followed by morpheme-to-frame association.
  • Jescheniak, J. D., & Levelt, W. J. M. (1994). Word frequency effects in speech production: Retrieval of syntactic information and of phonological form. Journal of Experimental Psychology: Learning, Memory, and Cognition, 20(4), 824-843.

    Abstract

    In 7 experiments the authors investigated the locus of word frequency effects in speech production. Experiment 1 demonstrated a frequency effect in picture naming that was robust over repetitions. Experiments 2, 3, and 7 excluded contributions from object identification and initiation of articulation. Experiments 4 and 5 investigated whether the effect arises in accessing the syntactic word (lemma) by using a grammatical gender decision task. Although a frequency effect was found, it dissipated under repeated access to word's gender. Experiment 6 tested whether the robust frequency effect arises in accessing the phonological form (lexeme) by having Ss translate words that produced homophones. Low-frequent homophones behaved like high-frequent controls, inheriting the accessing speed of their high-frequent homophone twins. Because homophones share the lexeme, not the lemma, this suggests a lexeme-level origin of the robust effect.
  • De Jong, N. H., Feldman, L. B., Schreuder, R., Pastizzo, M., & Baayen, R. H. (2002). The processing and representation of Dutch and English compounds: Peripheral morphological, and central orthographic effects. Brain and Language, 81(1-3), 555-567. doi:10.1006/brln.2001.2547.

    Abstract

    In this study, we use the association between various measures of the morphological family and decision latencies to reveal the way in which the components of Dutch and English compounds are processed. The results show that for constituents of concatenated compounds in both languages, a position-related token count of the morphological family plays a role, whereas English open compounds show an effect of a type count, similar to the effect of family size for simplex words. When Dutch compounds are written with an artificial space, they reveal no effect of type count, which shows that the differential effect for the English open compounds is not superficial. The final experiment provides converging evidence for the lexical consequences of the space in English compounds. Decision latencies for English simplex words are better predicted from counts of the morphological family that include concatenated and hyphenated but not open family members.
  • Jordens, P. (2002). Finiteness in early child Dutch. Linguistics, 40(4), 687-765. doi:10.1515/ling.2002.029.
  • Kearns, R. K., Norris, D., & Cutler, A. (2002). Syllable processing in English. In Proceedings of the 7th International Conference on Spoken Language Processing [ICSLP 2002] (pp. 1657-1660).

    Abstract

    We describe a reaction time study in which listeners detected word or nonword syllable targets (e.g. zoo, trel) in sequences consisting of the target plus a consonant or syllable residue (trelsh, trelshek). The pattern of responses differed from an earlier word-spotting study with the same material, in which words were always harder to find if only a consonant residue remained. The earlier results should thus not be viewed in terms of syllabic parsing, but in terms of a universal role for syllables in speech perception; words which are accidentally present in spoken input (e.g. sell in self) can be rejected when they leave a residue of the input which could not itself be a word.
  • Kempen, G., & Van Breugel, C. (2002). A workbench for visual-interactive grammar instruction at the secondary education level. In Proceedings of the 10th International CALL Conference (pp. 157-158). Antwerp: University of Antwerp.
  • Kempen, G. (1991). Conjunction reduction and gapping in clause-level coordination: An inheritance-based approach. Computational Intelligence, 7, 357-360. doi:10.1111/j.1467-8640.1991.tb00406.x.
  • Kempen, G. (1994). De mythe van het woordbeeld: Spellingherziening taalpsychologisch doorgelicht. Spektator, tijdschrift voor Neerlandistiek, 23, 292-301.
  • Kempen, G., Schotel, H., & Hoenkamp, E. (1982). Analyse-door-synthese van Nederlandse zinnen [Abstract]. De Psycholoog, 17, 509.
  • Kempen, G. (1971). [Review of the book General Psychology by N. Dember and J.J. Jenkins]. Nijmeegs Tijdschrift voor Psychologie, 19, 132-133.
  • Kempen, G. (1999). Fiets en (centri)fuge. Onze Taal, 68, 88.
  • Kempen, G. (1994). In de grammaticadiscussie is de empirie aan zet. Levende Talen, 486, 27-28.
  • Kempen, G., & Hoenkamp, E. (1982). Incremental sentence generation: Implications for the structure of a syntactic processor. In J. Horecký (Ed.), COLING 82. Proceedings of the Ninth International Conference on Computational Linguistics, Prague, July 5-10, 1982 (pp. 151-156). Amsterdam: North-Holland.

    Abstract

    Human speakers often produce sentences incrementally. They can start speaking having in mind only a fragmentary idea of what they want to say, and while saying this they refine the contents underlying subsequent parts of the utterance. This capability imposes a number of constraints on the design of a syntactic processor. This paper explores these constraints and evaluates some recent computational sentence generators from the perspective of incremental production.
  • Kempen, G., & De Vroomen, P. (Eds.). (1991). Informatiewetenschap 1991: Wetenschappelijke bijdragen aan de eerste STINFON-conferentie. Leiden: STINFON.
  • Kempen, G. (1994). Innovative language checking software for Dutch. In J. Van Gent, & E. Peeters (Eds.), Proceedings of the 2e Dag van het Document (pp. 99-100). Delft: TNO Technisch Physische Dienst.
  • Kempen, G. (1994). Klare taal: Zicht op zinsbouw. Natuur en Techniek, 62, 380-391.
  • Kempen, G. (1971). Het onthouden van eenvoudige zinnen met zijn en hebben als werkwoorden: Een experiment met steekwoordreaktietijden. Nijmeegs Tijdschrift voor Psychologie, 19, 262-274.
  • Kempen, G. (1994). Nederlands als computertaal. EMNET: Nieuwsbrief Elektronische Media, 2, 9-12.
  • Kempen, G. (1971). Opslag van woordbetekenissen in het semantisch geheugen. Nijmeegs Tijdschrift voor Psychologie, 19, 36-50.
  • Kempen, G., & Harbusch, K. (2002). Rethinking the architecture of human syntactic processing: The relationship between grammatical encoding and decoding. In Proceedings of the 35th Meeting of the Societas Linguistica Europaea. University of Potsdam.
  • Kempen, G., & Huijbers, P. (1983). The lexicalization process in sentence production and naming: Indirect election of words. Cognition, 14(2), 185-209. doi:10.1016/0010-0277(83)90029-X.

    Abstract

    A series of experiments is reported in which subjects describe simple visual scenes by means of both sentential and non-sentential responses. The data support the following statements about the lexicalization (word finding) process. (1) Words used by speakers in overt naming or sentence production responses are selected by a sequence of two lexical retrieval processes, the first yielding abstract pre-phonological items (Ll -items), the second one adding their phonological shapes (L2-items). (2) The selection of several Ll-items for a multi-word utterance can take place simultaneously. (3) A monitoring process is watching the output of Ll-lexicalization to check if it is in keeping with prevailing constraints upon utterance format. (4) Retrieval of the L2-item which corresponds with a given LI-item waits until the Ld-item has been checked by the monitor, and all other Ll-items needed for the utterance under construction have become available. A coherent picture of the lexicalization process begins to emerge when these characteristics are brought together with other empirical results in the area of naming and sentence production, e.g., picture naming reaction times (Seymour, 1979), speech errors (Garrett, 1980), and word order preferences (Bock, 1982).
  • Kempen, G. (1983). Wat betekent taalvaardigheid voor informatiesystemen? TNO project: Maandblad voor toegepaste wetenschappen, 11, 401-403.
  • Kempen, G. (1994). The unification space: A hybrid model of human syntactic processing [Abstract]. In Cuny 1994 - The 7th Annual CUNY Conference on Human Sentence Processing. March 17-19, 1994. CUNY Graduate Center, New York.
  • Kempen, G., & Dijkstra, A. (1994). Toward an integrated system for grammar, writing and spelling instruction. In L. Appelo, & F. De Jong (Eds.), Computer-Assisted Language Learning: Proceedings of the Seventh Twente Workshop on Language Technology (pp. 41-46). Enschede: University of Twente.
  • Kidd, E., & Bavin, E. L. (2002). English-speaking children's comprehension of relative clauses: Evidence for general-cognitive and language-specific constraints on development. Journal of Psycholinguistic Research, 31(6), 599-617. doi:10.1023/A:1021265021141.

    Abstract

    Children must possess some ability to process input in a meaningful manner to acquire language. The present study reports on data from an experiment investigating 3- to 5-year-old English-speaking children's understanding of restrictive relative clauses manipulated for embeddedness and focus. The results of the study showed that English-speaking children acquire right-branching before center-embedded structures. Comparisons made with data from Portuguese-speaking children suggest general-cognitive and language-specific constraints on development, and with respect to English, a “clause expansion” approach to processing in development
  • Kirsch, K., & Dittmar, N. (2002). [Review of the book Russlanddeutsche Sprachbiografien: Untersuchungen zur sprachlichen Integration von Aussiedlerfamilien by Katharina Meng]. Zeitschrift für Sprachwissenschaft, 21, 295-296.
  • Kita, S. (Ed.). (2002). 2002 Supplement (version 3) for the Manual for the field season 2001. Nijmegen: Max Planck Institute for Psycholinguistics.
  • Kita, S. (2002). Jesuchaa: kangaeru karada: Gesture: the body that thinks. Tokyo: Kaneko Shobo.
  • Klein, W. (Ed.). (2002). Sprache des Rechts II [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, 128.
  • Klein, W. (2002). Time in language (in Korean, translated by Soo-Song Shin). Seoul: Doseo-chul-phan Yeok lak.
  • Klein, W., & Musan, R. (Eds.). (1999). Das deutsche Perfekt [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (113).
  • Klein, W., & Rieck, B.-O. (1982). Der Erwerb der Personalpronomina im ungesteuerten Spracherwerb. Zeitschrift für Literaturwissenschaft und Linguistik, 45, 35-71.
  • Klein, W. (1982). Einige Bemerkungen zur Frageintonation. Deutsche Sprache, 4, 289-310.

    Abstract

    In the first, critical part of this study, a small sample of simple German sentences with their empirically determined pitch contours is used to demonstrate the incorrectness of numerous currently hold views of German sentence intonation. In the second, more constructive part, several interrogative sentence types are analysed and an attempt is made to show that intonation, besides other functions, indicates the permantently changing 'thematic score' in on-going discourse as well as certain validity claims.
  • Klein, W. (1982). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 12, 7-8.
  • Klein, W., & Dittmar, N. (1994). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (93), 7-8.
  • Klein, W., & Jungbluth, K. (Eds.). (2002). Deixis [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, 125.
  • Klein, W. (1971). Eine kommentierte Bibliographie zur Computerlinguistik. Linguistische Berichte, (11), 101-134.
  • Klein, W., & Jungbluth, K. (2002). Einleitung - Introduction. Zeitschrift für Literaturwissenschaft und Linguistik, 125, 5-9.
  • Klein, W. (1991). Geile Binsenbüschel, sehr intime Gespielen: Ein paar Anmerkungen über Arno Schmidt als Übersetzer. Zeitschrift für Literaturwissenschaft und Linguistik, 84, 124-129.
  • Klein, W., & Zimmermann, H. (1971). Lemmatisierter Index zu Georg Trakl, Dichtungen. Frankfurt am Main: Athenäum.
  • Klein, W., & Weissenborn, J. (Eds.). (1982). Here and there: Cross-linguistic studies on deixis and demonstration. Amsterdam: Benjamins.
  • Klein, W., & Dittmar, N. (Eds.). (1994). Interkulturelle Kommunikation [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (93).
  • Klein, W. (Ed.). (1983). Intonation [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (49).
  • Klein, W., & Von Stechow, A. (1982). Intonation und Bedeutung von Fokus. Konstanz: Universität Konstanz.
  • Klein, W. (1971). Parsing: Studien zur maschinellen Satzanalyse mit Abhängigkeitsgrammatiken und Transformationsgrammatiken. Frankfurt am Main: Athenäum.
  • Klein, W. (1982). Pronoms personnels et formes d'acquisition. Encrages, 8/9, 42-46.
  • Klein, W. (1991). Raumausdrücke. Linguistische Berichte, 132, 77-114.
  • Klein, W., & Von Stutterheim, C. (1991). Text structure and referential movement. Arbeitsberichte des Forschungsprogramms S&P: Sprache und Pragmatik, 22.
  • Klein, W. (Ed.). (1982). Speech, place, and action: Studies of language in context. New York: Wiley.
  • Klein, W. (1991). Was kann sich die Übersetzungswissenschaft von der Linguistik erwarten? Zeitschrift für Literaturwissenschaft und Linguistik, 84, 104-123.
  • Klein, W. (1994). Time in language. London: Routledge.
  • Klein, W. (1999). Wie sich das deutsche Perfekt zusammensetzt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (113), 52-85.
  • Klein, W. (Ed.). (1982). Zweitspracherwerb [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (45).
  • Klein, W. (1983). Vom Glück des Mißverstehens und der Trostlosigkeit der idealen Kommunikationsgemeinschaft. Zeitschrift für Literaturwissenschaft und Linguistik, 50, 128-140.
  • Knosche, T. R., & Bastiaansen, M. C. M. (2002). On the time resolution of event-related desynchronization: A simulation study. Clinical Neurophysiology, 113(5), 754-763. doi:10.1016/S1388-2457(02)00055-X.

    Abstract

    Objectives: To investigate the time resolution of different methods for the computation of event-related desynchronization/synchronization (ERD/ERS), including one based on Hilbert transform. Methods: In order to better understand the time resolution of ERD/ERS, which is a function of factors such as the exact computation method, the frequency under study, the number of trials, and the sampling frequency, we simulated sudden changes in oscillation amplitude as well as very short and closely spaced events. Results: Hilbert-based ERD yields very similar results to ERD integrated over predefined time intervals (block ERD), if the block length is half the period length of the studied frequency. ERD predicts the onset of a change in oscillation amplitude with an error margin of only 10–30 ms. On the other hand, the time the ERD response needs to climb to its full height after a sudden change in oscillation amplitude is quite long, i.e. between 200 and 500 ms. With respect to sensitivity to short oscillatory events, the ratio between sampling frequency and electroencephalographic frequency band plays a major role. Conclusions: (1) The optimal time interval for the computation of block ERD is half a period of the frequency under investigation. (2) Due to the slow impulse response, amplitude effects in the ERD may in reality be caused by duration differences. (3) Although ERD based on the Hilbert transform does not yield any significant advantages over classical ERD in terms of time resolution, it has some important practical advantages.
  • Kreuzer, H. (Ed.). (1971). Methodische Perspektiven [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (1/2).
  • Kuijpers, C., Van Donselaar, W., & Cutler, A. (2002). Perceptual effects of assimilation-induced violation of final devoicing in Dutch. In J. H. L. Hansen, & B. Pellum (Eds.), The 7th International Conference on Spoken Language Processing (pp. 1661-1664). Denver: ICSA.

    Abstract

    Voice assimilation in Dutch is an optional phonological rule which changes the surface forms of words and in doing so may violate the otherwise obligatory phonological rule of syllablefinal devoicing. We report two experiments examining the influence of voice assimilation on phoneme processing, in lexical compound words and in noun-verb phrases. Processing was not impaired in appropriate assimilation contexts across morpheme boundaries, but was impaired when devoicing was violated (a) in an inappropriate non-assimilatory) context, or (b) across a syntactic boundary.
  • Küntay, A. C., & Slobin, D. I. (2002). Putting interaction back into child language: Examples from Turkish. Psychology of Language and Communication, 6(1): 14.

    Abstract

    As in the case of other non-English languages, the study of the acquisition of Turkish has mostly focused on aspects of grammatical morphology and syntax, largely neglecting the study of the effect of interactional factors on child morphosyntax. This paper reviews indications from past research that studying input and adult-child discourse can facilitate the study of the acquisition of morphosyntax in the Turkish language. It also provides some recent studies of Turkish child language on the relationship of child-directed speech to the early acquisition of morphosyntax, and on the pragmatic features of a certain kind of discourse form in child-directed speech called variation sets.
  • Kuntay, A., & Ozyurek, A. (2002). Joint attention and the development of the use of demonstrative pronouns in Turkish. In B. Skarabela, S. Fish, & A. H. Do (Eds.), Proceedings of the 26th annual Boston University Conference on Language Development (pp. 336-347). Somerville, MA: Cascadilla Press.
  • Lausberg, H., & Kita, S. (2002). Dissociation of right and left gesture spaces in split-brain patients. Cortex, 38(5), 883-886. doi:10.1016/S0010-9452(08)70062-5.

    Abstract

    The present study investigates hemispheric specialisation in the use of space in communicative gestures. For this purpose, we investigate split-brain patients in whom spontaneous and distinct right hand gestures can only be controlled by the left hemisphere and vice versa, the left hand only by the right hemisphere. On this anatomical basis, we can infer hemispheric specialisation from the performances of the right and left hands. In contrast to left hand dyspraxia in tasks that require language processing, split-brain patients utilise their left hands in a meaningful way in visuo-constructive tasks such as copying drawings or block-design. Therefore, we conjecture that split-brain patients are capable of using their left hands for the communication of the content of visuo-spatial animations via gestural demonstration. On this basis, we further examine the use of space in communicative gestures by the right and left hands. McNeill and Pedelty (1995) noted for the split-brain patient N.G. that her iconic right hand gestures were exclusively displayed in the right personal space. The present study investigates systematically if there is indication for neglect of the left personal space in right hand gestures in split-brain patients.
  • Lausberg, H., & Kita, S. (2002). Dissociation of right and left hand gesture spaces in split-brain patients. Cortex, 38(5), 883-886. doi:10.1016/S0010-9452(08)70062-5.

    Abstract

    The present study investigates hemispheric specialisation in the use of space in communicative gestures. For this purpose, we investigate split-brain patients in whom spontaneous and distinct right hand gestures can only be controlled by the left hemisphere and vice versa, the left hand only by the right hemisphere. On this anatomical basis, we can infer hemispheric specialisation from the performances of the right and left hands. In contrast to left hand dyspraxia in tasks that require language processing, split-brain patients utilise their left hands in a meaningful way in visuo-constructive tasks such as copying drawings or block-design. Therefore, we conjecture that split-brain patients are capable of using their left hands for the communication of the content of visuo-spatial animations via gestural demonstration. On this basis, we further examine the use of space in communicative gestures by the right and left hands. McNeill and Pedelty (1995) noted for the split-brain patient N.G. that her iconic right hand gestures were exclusively displayed in the right personal space. The present study investigates systematically if there is indication for neglect of the left personal space in right hand gestures in split-brain patients.
  • Levelt, W. J. M. (2002). Picture naming and word frequency: Comments on Alario, Costa and Caramazza, Language and Cognitive Processes, 17(3), 299-319. Language and Cognitive Processes, 17(6), 663-671. doi:0.1080/01690960143000443.

    Abstract

    This commentary on Alario et al. (2002) addresses two issues: (1) Different from what the authors suggest, there are no theories of production claiming the phonological word to be the upper bound of advance planning before the onset of articulation; (2) Their picture naming study of word frequency effects on speech onset is inconclusive by lack of a crucial control, viz., of object recognition latency. This is a perennial problem in picture naming studies of word frequency and age of acquisition effects
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (1999). A developmental grammar for syllable structure in the production of child language. Brain and Language, 68, 291-299.

    Abstract

    The order of acquisition of Dutch syllable types by first language learners is analyzed as following from an initial ranking and subsequent rerankings of constraints in an optimality theoretic grammar. Initially, structural constraints are all ranked above faithfulness constraints, leading to core syllable (CV) productions only. Subsequently, faithfulness gradually rises to the highest position in the ranking, allowing more and more marked syllable types to appear in production. Local conjunctions of Structural constraints allow for a more detailed analysis.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). A theory of lexical access in speech production. Behavioral and Brain Sciences, 22, 1-38. doi:10.1017/S0140525X99001776.

    Abstract

    Preparing words in speech production is normally a fast and accurate process. We generate them two or three per second in fluent conversation; and overtly naming a clear picture of an object can easily be initiated within 600 msec after picture onset. The underlying process, however, is exceedingly complex. The theory reviewed in this target article analyzes this process as staged and feedforward. After a first stage of conceptual preparation, word generation proceeds through lexical selection, morphological and phonological encoding, phonetic encoding, and articulation itself. In addition, the speaker exerts some degree of output control, by monitoring of self-produced internal and overt speech. The core of the theory, ranging from lexical selection to the initiation of phonetic encoding, is captured in a computational model, called WEAVER + +. Both the theory and the computational model have been developed in interaction with reaction time experiments, particularly in picture naming or related word production paradigms, with the aim of accounting. for the real-time processing in normal word production. A comprehensive review of theory, model, and experiments is presented. The model can handle some of the main observations in the domain of speech errors (the major empirical domain for most other theories of lexical access), and the theory opens new ways of approaching the cerebral organization of speech production by way of high-temporal-resolution imaging.
  • Levelt, W. J. M. (1991). Die konnektionistische Mode. Sprache und Kognition, 10(2), 61-72.
  • Levelt, W. J. M., & Wheeldon, L. (1994). Do speakers have access to a mental syllabary? Cognition, 50, 239-269. doi:10.1016/0010-0277(94)90030-2.

    Abstract

    The first, theoretical part of this paper sketches a framework for phonological encoding in which the speaker successively generates phonological syllables in connected speech. The final stage of this process, phonetic encoding, consists of accessing articulatory gestural scores for each of these syllables in a "mental syllabary". The second, experimental part studies various predictions derived from this theory. The main finding is a syllable frequency effect: words ending in a high-frequent syllable are named faster than words ending in a low-frequent syllable. As predicted, this syllable frequency effect is independent of and additive to the effect of word frequency on naming latency. The effect, moreover, is not due to the complexity of the word-final syllable. In the General Discussion, the syllabary model is further elaborated with respect to phonological underspecification and activation spreading. Alternative accounts of the empirical findings in terms of core syllables and demisyllables are considered.
  • Levelt, W. J. M. (1999). Models of word production. Trends in Cognitive Sciences, 3, 223-232.

    Abstract

    Research on spoken word production has been approached from two angles. In one research tradition, the analysis of spontaneous or induced speech errors led to models that can account for speech error distributions. In another tradition, the measurement of picture naming latencies led to chronometric models accounting for distributions of reaction times in word production. Both kinds of models are, however, dealing with the same underlying processes: (1) the speaker’s selection of a word that is semantically and syntactically appropriate; (2) the retrieval of the word’s phonological properties; (3) the rapid syllabification of the word in context; and (4) the preparation of the corresponding articulatory gestures. Models of both traditions explain these processes in terms of activation spreading through a localist, symbolic network. By and large, they share the main levels of representation: conceptual/semantic, syntactic, phonological and phonetic. They differ in various details, such as the amount of cascading and feedback in the network. These research traditions have begun to merge in recent years, leading to highly constructive experimentation. Currently, they are like two similar knives honing each other. A single pair of scissors is in the making.
  • Levelt, W. J. M. (1983). Monitoring and self-repair in speech. Cognition, 14, 41-104. doi:10.1016/0010-0277(83)90026-4.

    Abstract

    Making a self-repair in speech typically proceeds in three phases. The first phase involves the monitoring of one’s own speech and the interruption of the flow of speech when trouble is detected. From an analysis of 959 spontaneous self-repairs it appears that interrupting follows detection promptly, with the exception that correct words tend to be completed. Another finding is that detection of trouble improves towards the end of constituents. The second phase is characterized by hesitation, pausing, but especially the use of so-called editing terms. Which editing term is used depends on the nature of the speech trouble in a rather regular fashion: Speech errors induce other editing terms than words that are merely inappropriate, and trouble which is detected quickly by the speaker is preferably signalled by the use of ‘uh’. The third phase consists of making the repair proper The linguistic well-formedness of a repair is not dependent on the speaker’s respecting the integriv of constituents, but on the structural relation between original utterance and repair. A bi-conditional well-formedness rule links this relation to a corresponding relation between the conjuncts of a coordination. It is suggested that a similar relation holds also between question and answer. In all three cases the speaker respects certain Istructural commitments derived from an original utterance. It was finally shown that the editing term plus the first word of the repair proper almost always contain sufficient information for the listener to decide how the repair should be related to the original utterance. Speakers almost never produce misleading information in this respect. It is argued that speakers have little or no access to their speech production process; self-monitoring is probably based on parsing one’s own inner or overt speech.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). Multiple perspectives on lexical access [authors' response ]. Behavioral and Brain Sciences, 22, 61-72. doi:10.1017/S0140525X99451775.
  • Levelt, W. J. M., & Plomp, R. (1962). Musical consonance and critical bandwidth. In Proceedings of the 4th International Congress Acoustics (pp. 55-55).
  • Levelt, W. J. M. (1982). Het lineariseringsprobleem van de spreker. Tijdschrift voor Taal- en Tekstwetenschap (TTT), 2(1), 1-15.

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