Publications

Displaying 101 - 200 of 1111
  • Bowerman, M. (1988). The child's expression of meaning: Expanding relationships among lexicon, syntax, and morphology [Reprint]. In M. B. Franklin, & S. S. Barten (Eds.), Child language: A reader (pp. 106-117). Oxford: Oxford University Press.

    Abstract

    Reprinted from: Bowerman, M. (1981). The child's expression of meaning: Expanding relationships among lexicon, syntax, and morphology. In H. Winitz (Ed.), Native language and foreign language acquisition (pp. 172 189). New York: New York Academy of Sciences.
  • Bowerman, M., & Choi, S. (2001). Shaping meanings for language: Universal and language-specific in the acquisition of semantic categories. In M. Bowerman, & S. C. Levinson (Eds.), Language acquisition and conceptual development (pp. 475-511). Cambridge: Cambridge University Press.
  • Bowerman, M. (1982). Starting to talk worse: Clues to language acquisition from children's late speech errors. In S. Strauss (Ed.), U shaped behavioral growth (pp. 101-145). New York: Academic Press.
  • Bowerman, M. (1985). What shapes children's grammars? In D. Slobin (Ed.), The crosslinguistic study of language acquisition (pp. 1257-1319). Hillsdale, N.J.: Lawrence Erlbaum.
  • Brand, S., & Ernestus, M. (2015). Reduction of obstruent-liquid-schwa clusters in casual French. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    This study investigated pronunciation variants of word-final obstruent-liquid-schwa (OLS) clusters in casual French and the variables predicting the absence of the phonemes in these clusters. In a dataset of 291 noun tokens extracted from a corpus of casual conversations, we observed that in 80.7% of the tokens, at least one phoneme was absent and that in no less than 15.5% the whole cluster was absent (e.g., /mis/ for ministre). Importantly, the probability of a phoneme being absent was higher if the following phoneme was absent as well. These data show that reduction can affect several phonemes at once and is not restricted to just a handful of (function) words. Moreover, our results demonstrate that the absence of each single phoneme is affected by the speaker's tendency to increase ease of articulation and to adapt a word's pronunciation variant to the time available.
  • Brascamp, J., Klink, P., & Levelt, W. J. M. (2015). The ‘laws’ of binocular rivalry: 50 years of Levelt’s propositions. Vision Research, 109, 20-37. doi:10.1016/j.visres.2015.02.019.

    Abstract

    It has been fifty years since Levelt’s monograph On Binocular Rivalry (1965) was published, but its four propositions that describe the relation between stimulus strength and the phenomenology of binocular rivalry remain a benchmark for theorists and experimentalists even today. In this review, we will revisit the original conception of the four propositions and the scientific landscape in which this happened. We will also provide a brief update concerning distributions of dominance durations, another aspect of Levelt’s monograph that has maintained a prominent presence in the field. In a critical evaluation of Levelt’s propositions against current knowledge of binocular rivalry we will then demonstrate that the original propositions are not completely compatible with what is known today, but that they can, in a straightforward way, be modified to encapsulate the progress that has been made over the past fifty years. The resulting modified, propositions are shown to apply to a broad range of bistable perceptual phenomena, not just binocular rivalry, and they allow important inferences about the underlying neural systems. We argue that these inferences reflect canonical neural properties that play a role in visual perception in general, and we discuss ways in which future research can build on the work reviewed here to attain a better understanding of these properties
  • Broeder, D., Offenga, F., & Willems, D. (2002). Metadata tools supporting controlled vocabulary services. In M. Rodriguez González, & C. Paz SuárezR Araujo (Eds.), Third international conference on language resources and evaluation (pp. 1055-1059). Paris: European Language Resources Association.

    Abstract

    Within the ISLE Metadata Initiative (IMDI) project a user-friendly editor to enter metadata descriptions and a browser operating on the linked metadata descriptions were developed. Both tools support the usage of Controlled Vocabulary (CV) repositories by means of the specification of an URL where the formal CV definition data is available.
  • Broeder, D., Wittenburg, P., Declerck, T., & Romary, L. (2002). LREP: A language repository exchange protocol. In M. Rodriguez González, & C. Paz Suárez Araujo (Eds.), Third international conference on language resources and evaluation (pp. 1302-1305). Paris: European Language Resources Association.

    Abstract

    The recent increase in the number and complexity of the language resources available on the Internet is followed by a similar increase of available tools for linguistic analysis. Ideally the user does not need to be confronted with the question in how to match tools with resources. If resource repositories and tool repositories offer adequate metadata information and a suitable exchange protocol is developed this matching process could be performed (semi-) automatically.
  • Broersma, M., & De Bot, K. (2001). De triggertheorie voor codewisseling: De oorspronkelijke en een aangepaste versie (‘The trigger theory for codeswitching: The original and an adjusted version’). Toegepaste Taalwetenschap in Artikelen, 65(1), 41-54.
  • Broersma, M. (2002). Comprehension of non-native speech: Inaccurate phoneme processing and activation of lexical competitors. In ICSLP-2002 (pp. 261-264). Denver: Center for Spoken Language Research, U. of Colorado Boulder.

    Abstract

    Native speakers of Dutch with English as a second language and native speakers of English participated in an English lexical decision experiment. Phonemes in real words were replaced by others from which they are hard to distinguish for Dutch listeners. Non-native listeners judged the resulting near-words more often as a word than native listeners. This not only happened when the phonemes that were exchanged did not exist as separate phonemes in the native language Dutch, but also when phoneme pairs that do exist in Dutch were used in word-final position, where they are not distinctive in Dutch. In an English bimodal priming experiment with similar groups of participants, word pairs were used which differed in one phoneme. These phonemes were hard to distinguish for the non-native listeners. Whereas in native listening both words inhibited each other, in non-native listening presentation of one word led to unresolved competition between both words. The results suggest that inaccurate phoneme processing by non-native listeners leads to the activation of spurious lexical competitors.
  • Brouwer, S., & Bradlow, A. R. (2015). The effect of target-background synchronicity on speech-in-speech recognition. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    The aim of the present study was to investigate whether speech-in-speech recognition is affected by variation in the target-background timing relationship. Specifically, we examined whether within trial synchronous or asynchronous onset and offset of the target and background speech influenced speech-in-speech recognition. Native English listeners were presented with English target sentences in the presence of English or Dutch background speech. Importantly, only the short-term temporal context –in terms of onset and offset synchrony or asynchrony of the target and background speech– varied across conditions. Participants’ task was to repeat back the English target sentences. The results showed an effect of synchronicity for English-in-English but not for English-in-Dutch recognition, indicating that familiarity with the English background lead in the asynchronous English-in-English condition might have attracted attention towards the English background. Overall, this study demonstrated that speech-in-speech recognition is sensitive to the target-background timing relationship, revealing an important role for variation in the local context of the target-background relationship as it extends beyond the limits of the time-frame of the to-be-recognized target sentence.
  • Brouwer, S., & Bradlow, A. R. (2015). The temporal dynamics of spoken word recognition in adverse listening conditions. Journal of Psycholinguistic Research. Advanced online publication. doi:10.1007/s10936-015-9396-9.

    Abstract

    This study examined the temporal dynamics of spoken word recognition in noise and background speech. In two visual-world experiments, English participants listened to target words while looking at four pictures on the screen: a target (e.g. candle), an onset competitor (e.g. candy), a rhyme competitor (e.g. sandal), and an unrelated distractor (e.g. lemon). Target words were presented in quiet, mixed with broadband noise, or mixed with background speech. Results showed that lexical competition changes throughout the observation window as a function of what is presented in the background. These findings suggest that, rather than being strictly sequential, stream segregation and lexical competition interact during spoken word recognition
  • Brown, P. (1983). [Review of the book Conversational routine: Explorations in standardized communication situations and prepatterned speech ed. by Florian Coulmas]. Language, 59, 215-219.
  • Brown, P. (1983). [Review of the books Mayan Texts I, II, and III ed. by Louanna Furbee-Losee]. International Journal of American Linguistics, 49, 337-341.
  • Brown, P. (2002). Everyone has to lie in Tzeltal. In S. Blum-Kulka, & C. E. Snow (Eds.), Talking to adults: The contribution of multiparty discourse to language acquisition (pp. 241-275). Mahwah, NJ: Erlbaum.

    Abstract

    In a famous paper Harvey Sacks (1974) argued that the sequential properties of greeting conventions, as well as those governing the flow of information, mean that 'everyone has to lie'. In this paper I show this dictum to be equally true in the Tzeltal Mayan community of Tenejapa, in southern Mexico, but for somewhat different reasons. The phenomenon of interest is the practice of routine fearsome threats to small children. Based on a longitudinal corpus of videotaped and tape-recorded naturally-occurring interaction between caregivers and children in five Tzeltal families, the study examines sequences of Tzeltal caregivers' speech aimed at controlling the children's behaviour and analyzes the children's developing pragmatic skills in handling such controlling utterances, from prelinguistic infants to age five and over. Infants in this society are considered to be vulnerable, easily scared or shocked into losing their 'souls', and therefore at all costs to be protected and hidden from outsiders and other dangers. Nonetheless, the chief form of control (aside from physically removing a child from danger) is to threaten, saying things like "Don't do that, or I'll take you to the clinic for an injection," These overt scare-threats - rarely actually realized - lead Tzeltal children by the age of 2;6 to 3;0 to the understanding that speech does not necessarily convey true propositions, and to a sensitivity to the underlying motivations for utterances distinct from their literal meaning. By age 4;0 children perform the same role to their younger siblings;they also begin to use more subtle non-true (e.g. ironic) utterances. The caretaker practice described here is related to adult norms of social lying, to the sociocultural context of constraints on information flow, social control through gossip, and the different notion of 'truth' that arises in the context of non-verifiability characteristic of a small-scale nonliterate society.
  • Brown, P. (2002). Language as a model for culture: Lessons from the cognitive sciences. In R. G. Fox, & B. J. King (Eds.), Anthropology beyond culture (pp. 169-192). Oxford: Berg.

    Abstract

    This paper surveys the concept of culture as used in recent work in cognitive science, assessing the very different (and sometimes minimal) role 'culture' plays in different branches and schools of linguistics: generative approaches, descriptive/comparative linguistics, typology, cognitive linguistics, semantics, pragmatics, psycholinguistics, linguistic and cognitive anthropology. The paper then describes research on one specific topic, spatial language and conceptualization, describes a methodology for studying it cross-linguistically and cross-culturally. Finally, it considers the implications of results in this area for how we can fruitfully conceptualize 'culture', arguing for an approach which shifts back and forth between individual mind and collective representations, between universals and particulars, and ties 'culture' to our biological roots.
  • Brown, P. (2015). Language, culture, and spatial cognition. In F. Sharifian (Ed.), Routledge Handbook on Language and Culture (pp. 294-309). London: Routledge.
  • Brown, P. (2001). Learning to talk about motion UP and DOWN in Tzeltal: Is there a language-specific bias for verb learning? In M. Bowerman, & S. C. Levinson (Eds.), Language acquisition and conceptual development (pp. 512-543). Cambridge: Cambridge University Press.

    Abstract

    The spatial vocabulary of the Mayan language Tzeltal is dominated by an Absolute system of spatial reckoning, whereby an "uphill/downhill" coordinate abstracted from the lay of the land is used to reckon spatial relationships on the horizontal in both small-scale and long distance space. This system is used in lieu of a Front/Back/Left/Right system which does not exist in this language. The spatial vocabulary dedicated to this system (which I refer to in general as the UP/DOWN vocabulary) includes intransitive motion verbs (roughly translatable as "ascend"/"descend"), their transitivized counterparts ("make it ascend/descend"), directional adverbs ("uphillwards"/"downhillwards"), and possessed relational nouns ("uphill/downhill in relation to it"). This same vocabulary applies to spatial relations on the vertical axis. Two seemingly contradictory observations about children's early meanings for the spatial verbs dedicated to this system motivate the proposal put forward in this paper. On the one hand, Tzeltal children's UP/DOWN vocabulary shows very early sensitivity to the semantic structure of the language they are learning: the meanings for these verbs are from the first usages attached to the slope of the land, and to particular places; there is no evidence of an initial preference for the vertical meaning. On the other hand, children's meanings remain for a long time too specific, and errors of interpretation/production (using the verbs to mean 'local slope of land' rather than 'overall N/S slope of land direction) are evident in verbal productions of some children as late as age 7 or 8. The proposal is made that the highly specific nature of Tzeltal verbs at the basic level influences the children's hypotheses about what kinds of meanings verbs can have.
  • Brown, P. (2001). Repetition. In K. Duranti (Ed.), Key terms in language and culture (pp. 219-222). Oxford: Blackwell.

    Abstract

    This is a reprint of the Brown 1999 article.
  • Brown, P. (1991). Sind Frauen höflicher? Befunde aus einer Maya-Gemeinde. In S. Günther, & H. Kotthoff (Eds.), Von fremden Stimmen: Weibliches und männliches Sprechen im Kulturvergleich. Frankfurt am Main: Suhrkamp.

    Abstract

    This is a German translation of Brown 1980, How and why are women more polite: Some evidence from a Mayan community.
  • Brown, P. (2015). Space: Linguistic expression of. In J. D. Wright (Ed.), International Encyclopedia of the Social and Behavioral Sciences (2nd ed.) Vol. 23 (pp. 89-93). Amsterdam: Elsevier. doi:10.1016/B978-0-08-097086-8.57017-2.
  • Brown, P. (2001). Politeness and language. In N. Smelser, & P. Baltes (Eds.), International encyclopedia of the social and behavioral sciences (pp. 11620-11624). Oxford: Elsevier Sciences.

    Abstract

    This is an encyclopedia entry surveying research and theoretical approaches to politeness phenomena in language usage.
  • Brown, P. (2015). Politeness and language. In J. D. Wright (Ed.), The International Encyclopedia of the Social and Behavioural Sciences (IESBS), (2nd ed.) (pp. 326-330). Amsterdam: Elsevier. doi:10.1016/B978-0-08-097086-8.53072-4.
  • Brown-Schmidt, S., & Konopka, A. E. (2015). Processes of incremental message planning during conversation. Psychonomic Bulletin & Review, 22, 833-843. doi:10.3758/s13423-014-0714-2.

    Abstract

    Speaking begins with the formulation of an intended preverbal message and linguistic encoding of this information. The transition from thought to speech occurs incrementally, with cascading planning at subsequent levels of production. In this article, we aim to specify the mechanisms that support incremental message preparation. We contrast two hypotheses about the mechanisms responsible for incorporating message-level information into a linguistic plan. According to the Initial Preparation view, messages can be encoded as fluent utterances if all information is ready before speaking begins. By contrast, on the Continuous Incrementality view, messages can be continually prepared and updated throughout the production process, allowing for fluent production even if new information is added to the message while speaking is underway. Testing these hypotheses, eye-tracked speakers in two experiments produced unscripted, conjoined noun phrases with modifiers. Both experiments showed that new message elements can be incrementally incorporated into the utterance even after articulation begins, consistent with a Continuous Incrementality view of message planning, in which messages percolate to linguistic encoding immediately as that information becomes available in the mind of the speaker. We conclude by discussing the functional role of incremental message planning in conversational speech and the situations in which this continuous incremental planning would be most likely to be observed
  • Brucato, N., Guadalupe, T., Franke, B., Fisher, S. E., & Francks, C. (2015). A schizophrenia-associated HLA locus affects thalamus volume and asymmetry. Brain, Behavior, and Immunity, 46, 311-318. doi:10.1016/j.bbi.2015.02.021.

    Abstract

    Genes of the Major Histocompatibility Complex (MHC) have recently been shown to have neuronal functions in the thalamus and hippocampus. Common genetic variants in the Human Leukocyte Antigens (HLA) region, human homologue of the MHC locus, are associated with small effects on susceptibility to schizophrenia, while volumetric changes of the thalamus and hippocampus have also been linked to schizophrenia. We therefore investigated whether common variants of the HLA would affect volumetric variation of the thalamus and hippocampus. We analyzed thalamus and hippocampus volumes, as measured using structural magnetic resonance imaging, in 1.265 healthy participants. These participants had also been genotyped using genome-wide single nucleotide polymorphism (SNP) arrays. We imputed genotypes for single nucleotide polymorphisms at high density across the HLA locus, as well as HLA allotypes and HLA amino acids, by use of a reference population dataset that was specifically targeted to the HLA region. We detected a significant association of the SNP rs17194174 with thalamus volume (nominal P=0.0000017, corrected P=0.0039), as well as additional SNPs within the same region of linkage disequilibrium. This effect was largely lateralized to the left thalamus and is localized within a genomic region previously associated with schizophrenia. The associated SNPs are also clustered within a potential regulatory element, and a region of linkage disequilibrium that spans genes expressed in the thalamus, including HLA-A. Our data indicate that genetic variation within the HLA region influences the volume and asymmetry of the human thalamus. The molecular mechanisms underlying this association may relate to HLA influences on susceptibility to schizophrenia
  • Bruggeman, L., & Janse, E. (2015). Older listeners' decreased flexibility in adjusting to changes in speech signal reliability. In M. Wolters, J. Linvingstone, B. Beattie, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). London: International Phonetic Association.

    Abstract

    Under noise or speech reductions, young adult listeners flexibly adjust the parameters of lexical activation and competition to allow for speech signal unreliability. Consequently, mismatches in the input are treated more leniently such that lexical candidates are not immediately deactivated. Using eyetracking, we assessed whether this modulation of recognition dynamics also occurs for older listeners. Dutch participants (aged 60+) heard Dutch sentences containing a critical word while viewing displays of four line drawings. The name of one picture shared either onset or rhyme with the critical word (i.e., was a phonological competitor). Sentences were either clear and noise-free, or had several phonemes replaced by bursts of noise. A larger preference for onset competitors than for rhyme competitors was observed in both clear and noise conditions; performance did not alter across condition. This suggests that dynamic adjustment of spoken-word recognition parameters in response to noise is less available to older listeners.
  • Brugman, H., Levinson, S. C., Skiba, R., & Wittenburg, P. (2002). The DOBES archive: It's purpose and implementation. In P. Austin, H. Dry, & P. Wittenburg (Eds.), Proceedings of the international LREC workshop on resources and tools in field linguistics (pp. 11-11). Paris: European Language Resources Association.
  • Brugman, H., Spenke, H., Kramer, M., & Klassmann, A. (2002). Multimedia annotation with multilingual input methods and search support.
  • Brugman, H., Wittenburg, P., Levinson, S. C., & Kita, S. (2002). Multimodal annotations in gesture and sign language studies. In M. Rodriguez González, & C. Paz Suárez Araujo (Eds.), Third international conference on language resources and evaluation (pp. 176-182). Paris: European Language Resources Association.

    Abstract

    For multimodal annotations an exhaustive encoding system for gestures was developed to facilitate research. The structural requirements of multimodal annotations were analyzed to develop an Abstract Corpus Model which is the basis for a powerful annotation and exploitation tool for multimedia recordings and the definition of the XML-based EUDICO Annotation Format. Finally, a metadata-based data management environment has been setup to facilitate resource discovery and especially corpus management. Bt means of an appropriate digitization policy and their online availability researchers have been able to build up a large corpus covering gesture and sign language data.
  • Bull, L. E., Oliver, C., Callaghan, E., & Woodcock, K. A. (2015). Increased Exposure to Rigid Routines can Lead to Increased Challenging Behavior Following Changes to Those Routines. Journal of Autism and Developmental Disorders, 45(6), 1569-1578. doi:10.1007/s10803-014-2308-2.

    Abstract

    Several neurodevelopmental disorders are associated with preference for routine and challenging behavior following changes to routines. We examine individuals with Prader–Willi syndrome, who show elevated levels of this behavior, to better understand how previous experience of a routine can affect challenging behavior elicited by disruption to that routine. Play based challenges exposed 16 participants to routines, which were either adhered to or changed. Temper outburst behaviors, heart rate and movement were measured. As participants were exposed to routines for longer before a change (between 10 and 80 min; within participants), more temper outburst behaviors were elicited by changes. Increased emotional arousal was also elicited, which was indexed by heart rate increases not driven by movement. Further study will be important to understand whether current intervention approaches that limit exposure to changes, may benefit from the structured integration of flexibility to ensure that the opportunity for routine establishment is also limited.

    Additional information

    10803_2014_2308_MOESM1_ESM.docx
  • Bulut, T., & Hagoort, P. (2024). Contributions of the left and right thalami to language: A meta-analytic approach. Brain Structure & Function. Advance online publication. doi:10.1007/s00429-024-02795-3.

    Abstract

    Background: Despite a pervasive cortico-centric view in cognitive neuroscience, subcortical structures including the thalamus have been shown to be increasingly involved in higher cognitive functions. Previous structural and functional imaging studies demonstrated cortico-thalamo-cortical loops which may support various cognitive functions including language. However, large-scale functional connectivity of the thalamus during language tasks has not been examined before. Methods: The present study employed meta-analytic connectivity modeling to identify language-related coactivation patterns of the left and right thalami. The left and right thalami were used as regions of interest to search the BrainMap functional database for neuroimaging experiments with healthy participants reporting language-related activations in each region of interest. Activation likelihood estimation analyses were then carried out on the foci extracted from the identified studies to estimate functional convergence for each thalamus. A functional decoding analysis based on the same database was conducted to characterize thalamic contributions to different language functions. Results: The results revealed bilateral frontotemporal and bilateral subcortical (basal ganglia) coactivation patterns for both the left and right thalami, and also right cerebellar coactivations for the left thalamus, during language processing. In light of previous empirical studies and theoretical frameworks, the present connectivity and functional decoding findings suggest that cortico-subcortical-cerebellar-cortical loops modulate and fine-tune information transfer within the bilateral frontotemporal cortices during language processing, especially during production and semantic operations, but also other language (e.g., syntax, phonology) and cognitive operations (e.g., attention, cognitive control). Conclusion: The current findings show that the language-relevant network extends beyond the classical left perisylvian cortices and spans bilateral cortical, bilateral subcortical (bilateral thalamus, bilateral basal ganglia) and right cerebellar regions.

    Additional information

    supplementary information
  • Butterfield, S., & Cutler, A. (1988). Segmentation errors by human listeners: Evidence for a prosodic segmentation strategy. In W. Ainsworth, & J. Holmes (Eds.), Proceedings of SPEECH ’88: Seventh Symposium of the Federation of Acoustic Societies of Europe: Vol. 3 (pp. 827-833). Edinburgh: Institute of Acoustics.
  • Byun, K.-S., & Byun, E.-J. (2015). Becoming Friends with International Sign. Seoul: Sign Language Dandelion.
  • Cablitz, G. (2002). The acquisition of an absolute system: learning to talk about space in Marquesan (Oceanic, French Polynesia). In E. V. Clark (Ed.), Space in language location, motion, path, and manner (pp. 40-49). Stanford: Center for the Study of Language & Information (Electronic proceedings.
  • Cablitz, G. (2002). Marquesan: A grammar of space. PhD Thesis, Christian Albrechts U., Kiel.
  • Caldwell-Harris, C. L., Lancaster, A., Ladd, D. R., Dediu, D., & Christiansen, M. H. (2015). Factors influencing sensitivity to lexical tone in an artificial language: Implications for second language learning. Studies in Second Language Acquisition, 37(2), 335-357. doi:10.1017/S0272263114000849.

    Abstract

    This study examined whether musical training, ethnicity, and experience with a natural tone language influenced sensitivity to tone while listening to an artificial tone language. The language was designed with three tones, modeled after level-tone African languages. Participants listened to a 15-min random concatenation of six 3-syllable words. Sensitivity to tone was assessed using minimal pairs differing only in one syllable (nonword task: e.g., to-kà-su compared to ca-fí-to) or only in tone (tone task: e.g., to-kà-su compared to to-ká-su). Proficiency in an East Asian heritage language was the strongest predictor of success on the tone task. Asians without tone language experience were no better than other ethnic groups. We conclude by considering implications for research on second language learning, especially as approached through artificial language learning.
  • Calkoen, F., Vervat, C., van Pel, M., de Haas, V., Vijfhuizen, L., Eising, E., Kroes, W., Hoen, P., van den Heuvel-Eibrink, M., Egeler, R., Van Tol, M., & Ball, L. (2015). Despite differential gene expression profiles pediatric MDS derived mesenchymal stromal cells display functionality in vitro. Stem Cell Research, 14(2), 198-210. doi:10.1016/j.scr.2015.01.006.

    Abstract

    Pediatric myelodysplastic syndrome (MDS) is a heterogeneous disease covering a spectrum ranging from aplasia (RCC) to myeloproliferation (RAEB(t)). In adult-type MDS there is increasing evidence for abnormal function of the bone-marrow microenvironment. Here, we extensively studied the mesenchymal stromal cells (MSCs) derived from children with MDS. MSCs were expanded from the bone-marrow of 17 MDS patients (RCC: n = 10 and advanced MDS: n = 7) and pediatric controls (n = 10). No differences were observed with respect to phenotype, differentiation capacity, immunomodulatory capacity or hematopoietic support. mRNA expression analysis by Deep-SAGE revealed increased IL-6 expression in RCC- and RAEB(t)-MDS. RCC-MDS MSC expressed increased levels of DKK3, a protein associated with decreased apoptosis. RAEB(t)-MDS revealed increased CRLF1 and decreased DAPK1 expressions. This pattern has been associated with transformation in hematopoietic malignancies. Genes reported to be differentially expressed in adult MDS-MSC did not differ between MSC of pediatric MDS and controls. An altered mRNA expression profile, associated with cell survival and malignant transformation, of MSC derived from children with MDS strengthens the hypothesis that the micro-environment is of importance in this disease. Our data support the understanding that pediatric and adult MDS are two different diseases. Further evaluation of the pathways involved might reveal additional therapy targets.
  • Calkoen, F. G., Vervat, C., Eising, E., Vijfhuizen, L. S., 't Hoen, P.-B.-A., van den Heuvel-Eibrink, M. M., & Egeler, R. M. (2015). Gene-expression and in vitro function of mesenchymal stromal cells are affected in juvenile myelomonocytic leukemia. Haematologica, 100(11), 1434-1441. doi:10.3324/haematol.2015.126938.

    Abstract

    An aberrant interaction between hematopoietic stem cells and mesenchymal stromal cells has been linked to disease and shown to contribute to the pathophysiology of hematologic malignancies in murine models. Juvenile myelomonocytic leukemia is an aggressive malignant disease affecting young infants. Here we investigated the impact of juvenile myelomonocytic leukemia on mesenchymal stromal cells. Mesenchymal stromal cells were expanded from bone marrow samples of patients at diagnosis (n=9) and after hematopoietic stem cell transplantation (n=7; from 5 patients) and from healthy children (n=10). Cells were characterized by phenotyping, differentiation, gene expression analysis (of controls and samples obtained at diagnosis) and in vitro functional studies assessing immunomodulation and hematopoietic support. Mesenchymal stromal cells from patients did not differ from controls in differentiation capacity nor did they differ in their capacity to support in vitro hematopoiesis. Deep-SAGE sequencing revealed differential mRNA expression in patient-derived samples, including genes encoding proteins involved in immunomodulation and cell-cell interaction. Selected gene expression normalized during remission after successful hematopoietic stem cell transplantation. Whereas natural killer cell activation and peripheral blood mononuclear cell proliferation were not differentially affected, the suppressive effect on monocyte to dendritic cell differentiation was increased by mesenchymal stromal cells obtained at diagnosis, but not at time of remission. This study shows that active juvenile myelomonocytic leukemia affects the immune response-related gene expression and function of mesenchymal stromal cells. In contrast, the differential gene expression of hematopoiesis-related genes could not be supported by functional data. Decreased immune surveillance might contribute to the therapy resistance and progression in juvenile myelomonocytic leukemia.
  • Casillas, M., De Vos, C., Crasborn, O., & Levinson, S. C. (2015). The perception of stroke-to-stroke turn boundaries in signed conversation. In D. C. Noelle, R. Dale, A. S. Warlaumont, J. Yoshimi, T. Matlock, C. D. Jennings, & P. R. Maglio (Eds.), Proceedings of the 37th Annual Meeting of the Cognitive Science Society (CogSci 2015) (pp. 315-320). Austin, TX: Cognitive Science Society.

    Abstract

    Speaker transitions in conversation are often brief, with minimal vocal overlap. Signed languages appear to defy this pattern with frequent, long spans of simultaneous signing. But recent evidence suggests that turn boundaries in signed language may only include the content-bearing parts of the turn (from the first stroke to the last), and not all turn-related movement (from first preparation to final retraction). We tested whether signers were able to anticipate “stroke-to-stroke” turn boundaries with only minimal conversational context. We found that, indeed, signers anticipated turn boundaries at the ends of turn-final strokes. Signers often responded early, especially when the turn was long or contained multiple possible end points. Early responses for long turns were especially apparent for interrogatives—long interrogative turns showed much greater anticipation compared to short ones.
  • Casillas, M., Foushee, R., Méndez Girón, J., Polian, G., & Brown, P. (2024). Little evidence for a noun bias in Tseltal spontaneous speech. First Language. Advance online publication. doi:10.1177/01427237231216571.

    Abstract

    This study examines whether children acquiring Tseltal (Mayan) demonstrate a noun bias – an overrepresentation of nouns in their early vocabularies. Nouns, specifically concrete and animate nouns, are argued to universally predominate in children’s early vocabularies because their referents are naturally available as bounded concepts to which linguistic labels can be mapped. This early advantage for noun learning has been documented using multiple methods and across a diverse collection of language populations. However, past evidence bearing on a noun bias in Tseltal learners has been mixed. Tseltal grammatical features and child–caregiver interactional patterns dampen the salience of nouns and heighten the salience of verbs, leading to the prediction of a diminished noun bias and perhaps even an early predominance of verbs. We here analyze the use of noun and verb stems in children’s spontaneous speech from egocentric daylong recordings of 29 Tseltal learners between 0;9 and 4;4. We find weak to no evidence for a noun bias using two separate analytical approaches on the same data; one analysis yields a preliminary suggestion of a flipped outcome (i.e. a verb bias). We discuss the implications of these findings for broader theories of learning bias in early lexical development.
  • Ceroni, F., Simpson, N. H., Francks, C., Baird, G., Conti-Ramsden, G., Clark, A., Bolton, P. F., Hennessy, E. R., Donnelly, P., Bentley, D. R., Martin, H., IMGSAC, SLI Consortium, WGS500 Consortium, Parr, J., Pagnamenta, A. T., Maestrini, E., Bacchelli, E., Fisher, S. E., & Newbury, D. F. (2015). Reply to Pembrey et al: ‘ZNF277 microdeletions, specific language impairment and the meiotic mismatch methylation (3M) hypothesis’. European Journal of Human Genetics, 23, 1113-1115. doi:10.1038/ejhg.2014.275.
  • Çetinçelik, M., Rowland, C. F., & Snijders, T. M. (2024). Does the speaker’s eye gaze facilitate infants’ word segmentation from continuous speech? An ERP study. Developmental Science, 27(2): e13436. doi:10.1111/desc.13436.

    Abstract

    The environment in which infants learn language is multimodal and rich with social cues. Yet, the effects of such cues, such as eye contact, on early speech perception have not been closely examined. This study assessed the role of ostensive speech, signalled through the speaker's eye gaze direction, on infants’ word segmentation abilities. A familiarisation-then-test paradigm was used while electroencephalography (EEG) was recorded. Ten-month-old Dutch-learning infants were familiarised with audio-visual stories in which a speaker recited four sentences with one repeated target word. The speaker addressed them either with direct or with averted gaze while speaking. In the test phase following each story, infants heard familiar and novel words presented via audio-only. Infants’ familiarity with the words was assessed using event-related potentials (ERPs). As predicted, infants showed a negative-going ERP familiarity effect to the isolated familiarised words relative to the novel words over the left-frontal region of interest during the test phase. While the word familiarity effect did not differ as a function of the speaker's gaze over the left-frontal region of interest, there was also a (not predicted) positive-going early ERP familiarity effect over right fronto-central and central electrodes in the direct gaze condition only. This study provides electrophysiological evidence that infants can segment words from audio-visual speech, regardless of the ostensiveness of the speaker's communication. However, the speaker's gaze direction seems to influence the processing of familiar words.
  • Chalfoun, A., Rossi, G., & Stivers, T. (2024). The magic word? Face-work and the functions of 'please' in everyday requests. Social Psychology Quarterly. doi:10.1177/01902725241245141.

    Abstract

    Expressions of politeness such as 'please' are prominent elements of interactional conduct that are explicitly targeted in early socialization and are subject to cultural expectations around socially desirable behavior. Yet their specific interactional functions remain poorly understood. Using conversation analysis supplemented with systematic coding, this study investigates when and where interactants use 'please' in everyday requests. We find that 'please' is rare, occurring in only 7 percent of request attempts. Interactants use 'please' to manage face-threats when a request is ill fitted to its immediate interactional context. Within this, we identify two environments in which 'please' prototypically occurs. First, 'please' is used when the requestee has demonstrated unwillingness to comply. Second, 'please' is used when the request is intrusive due to its incompatibility with the requestee’s engagement in a competing action trajectory. Our findings advance research on politeness and extend Goffman’s theory of face-work, with particular salience for scholarship on request behavior.
  • Chang, F., Bauman, M., Pappert, S., & Fitz, H. (2015). Do lemmas speak German?: A verb position effect in German structural priming. Cognitive Science, 39(5), 1113-1130. doi:10.1111/cogs.12184.

    Abstract

    Lexicalized theories of syntax often assume that verb-structure regularities are mediated by lemmas, which abstract over variation in verb tense and aspect. German syntax seems to challenge this assumption, because verb position depends on tense and aspect. To examine how German speakers link these elements, a structural priming study was performed which varied syntactic structure, verb position (encoded by tense and aspect), and verb overlap. Abstract structural priming was found, both within and across verb position, but priming was larger when the verb position was the same between prime and target. Priming was boosted by verb overlap, but there was no interaction with verb position. The results can be explained by a lemma model where tense and aspect are linked to structural choices in German. Since the architecture of this lemma model is not consistent with results from English, a connectionist model was developed which could explain the cross-linguistic variation in the production system. Together, these findings support the view that language learning plays an important role in determining the nature of structural priming in different languages
  • Chen, A. (2015). Children’s use of intonation in reference and the role of input. In L. Serratrice, & S. E. M. Allen (Eds.), The acquisition of reference (pp. 83-104). Amsterdam: Benjamins.

    Abstract

    Studies on children’s use of intonation in reference are few in number but are diverse in terms of theoretical frameworks and intonational parameters. In the current review, I present a re-analysis of the referents in each study, using a three-dimension approach (i.e. referential givenness-newness, relational givenness-newness, contrast), discuss the use of intonation at two levels (phonetic, phonological), and compare findings from different studies within a single framework. The patterns stemming from these studies may be limited in generalisability but can serve as initial hypotheses for future work. Furthermore, I examine the role of input as available in infant direct speech in the acquisition of intonational encoding of referents. In addition, I discuss how future research can advance our knowledge.

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  • Chen, J., Calhoun, V. D., Arias-Vasquez, A., Zwiers, M. P., Van Hulzen, K., Fernández, G., Fisher, S. E., Franke, B., Turner, J. A., & Liu, J. (2015). G-Protein genomic association with normal variation in gray matter density. Human Brain Mapping, 36(11), 4272-4286. doi:10.1002/hbm.22916.

    Abstract

    While detecting genetic variations underlying brain structures helps reveal mechanisms of neural disorders, high data dimensionality poses a major challenge for imaging genomic association studies. In this work, we present the application of a recently proposed approach, parallel independent component analysis with reference (pICA-R), to investigate genomic factors potentially regulating gray matter variation in a healthy population. This approach simultaneously assesses many variables for an aggregate effect and helps to elicit particular features in the data. We applied pICA-R to analyze gray matter density (GMD) images (274,131 voxels) in conjunction with single nucleotide polymorphism (SNP) data (666,019 markers) collected from 1,256 healthy individuals of the Brain Imaging Genetics (BIG) study. Guided by a genetic reference derived from the gene GNA14, pICA-R identified a significant SNP-GMD association (r = −0.16, P = 2.34 × 10−8), implying that subjects with specific genotypes have lower localized GMD. The identified components were then projected to an independent dataset from the Mind Clinical Imaging Consortium (MCIC) including 89 healthy individuals, and the obtained loadings again yielded a significant SNP-GMD association (r = −0.25, P = 0.02). The imaging component reflected GMD variations in frontal, precuneus, and cingulate regions. The SNP component was enriched in genes with neuronal functions, including synaptic plasticity, axon guidance, molecular signal transduction via PKA and CREB, highlighting the GRM1, PRKCH, GNA12, and CAMK2B genes. Collectively, our findings suggest that GNA12 and GNA14 play a key role in the genetic architecture underlying normal GMD variation in frontal and parietal regions
  • Chen, A., Rietveld, T., & Gussenhoven, C. (2001). Language-specific effects of pitch range on the perception of universal intonational meaning. In Eurospeech 2001 (pp. 1403-1406).
  • Chen, A., Rietveld, T., & Gussenhoven, C. (2001). Language-specific effects of pitch range on the perception of universal intonational meaning. In P. Dalsgaard, B. Lindberg, & H. Benner (Eds.), Proceedings of the 7th European Conference on Speech Communication and Technology, II (pp. 1403-1406). Aalborg: University of Aalborg.

    Abstract

    Two groups of listeners, with Dutch and British English as their native language judged stimuli in Dutch and British English, respectively, on the scales CONFIDENT vs. NOT CONFIDENT and FRIENDLY vs. NOT FRIENDLY, two meanings derived from Ohala's universal Frequency Code. The stimuli, which were lexically equivalent, were varied in pitch contour and pitch range. In both languages, the perceived degree of confidence decreases and that of friendliness increases when the pitch range is raised, as predicted by the Frequency Code. However, at identical pitch ranges, British English is perceived as more confident and more friendly than Dutch. We argue that this difference in degree of the use of the Frequency Code is due to the difference in the standard pitch ranges of Dutch and British English.
  • Chen, A., Gussenhoven, C., & Rietveld, T. (2002). Language-specific uses of the effort code. In B. Bel, & I. Marlien (Eds.), Proceedings of the 1st Conference on Speech Prosody (pp. 215-218). Aix=en-Provence: Université de Provence.

    Abstract

    Two groups of listeners with Dutch and British English language backgrounds judged Dutch and British English utterances, respectively, which varied in the intonation contour on the scales EMPHATIC vs. NOT EMPHATIC and SURPRISED vs. NOT SURPRISED, two meanings derived from the Effort Code. The stimuli, which differed in sentence mode but were otherwise lexically equivalent, were varied in peak height, peak alignment, end pitch, and overall register. In both languages, there are positive correlations between peak height and degree of emphasis, between peak height and degree of surprise, between peak alignment and degree of surprise, and between pitch register and degree of surprise. However, in all these cases, Dutch stimuli lead to larger perceived meaning differences than the British English stimuli. This difference in the extent to which increased pitch height triggers increases in perceived emphasis and surprise is argued to be due to the difference in the standard pitch ranges between Dutch and British English. In addition, we found a positive correlation between pitch register and the degree of emphasis in Dutch, but a negative correlation in British English. This is an unexpected difference, which illustrates a case of ambiguity in the meaning of pitch.
  • Cho, T. (2002). The effects of prosody on articulation in English. New York: Routledge.
  • Cho, T., Jun, S.-A., & Ladefoged, P. (2002). Acoustic and aerodynamic correlates of Korean stops and fricatives. Journal of Phonetics, 30(2), 193-228. doi:10.1006/jpho.2001.0153.

    Abstract

    This study examines acoustic and aerodynamic characteristics of consonants in standard Korean and in Cheju, an endangered Korean language. The focus is on the well-known three-way distinction among voiceless stops (i.e., lenis, fortis, aspirated) and the two-way distinction between the voiceless fricatives /s/ and /s*/. While such a typologically unusual contrast among voiceless stops has long drawn the attention of phoneticians and phonologists, there is no single work in the literature that discusses a body of data representing a relatively large number of speakers. This study reports a variety of acoustic and aerodynamic measures obtained from 12 Korean speakers (four speakers of Seoul Korean and eight speakers of Cheju). Results show that, in addition to findings similar to those reported by others, there are three crucial points worth noting. Firstly, lenis, fortis, and aspirated stops are systematically differentiated from each other by the voice quality of the following vowel. Secondly, these stops are also differentiated by aerodynamic mechanisms. The aspirated and fortis stops are similar in supralaryngeal articulation, but employ a different relation between intraoral pressure and flow. Thirdly, our study suggests that the fricative /s/ is better categorized as “lenis” rather than “aspirated”. The paper concludes with a discussion of the implications of Korean data for theories of the voicing contrast and their phonological representations.
  • Choi, J., Broersma, M., & Cutler, A. (2015). Enhanced processing of a lost language: Linguistic knowledge or linguistic skill? In Proceedings of Interspeech 2015: 16th Annual Conference of the International Speech Communication Association (pp. 3110-3114).

    Abstract

    Same-different discrimination judgments for pairs of Korean stop consonants, or of Japanese syllables differing in phonetic segment length, were made by adult Korean adoptees in the Netherlands, by matched Dutch controls, and Korean controls. The adoptees did not outdo either control group on either task, although the same individuals had performed significantly better than matched controls on an identification learning task. This suggests that early exposure to multiple phonetic systems does not specifically improve acoustic-phonetic skills; rather, enhanced performance suggests retained language knowledge.
  • Choi, S., & Bowerman, M. (1991). Learning to express motion events in English and Korean: The influence of language-specific lexicalization patterns. Cognition, 41, 83-121. doi:10.1016/0010-0277(91)90033-Z.

    Abstract

    English and Korean differ in how they lexicalize the components of motionevents. English characteristically conflates Motion with Manner, Cause, or Deixis, and expresses Path separately. Korean, in contrast, conflates Motion with Path and elements of Figure and Ground in transitive clauses for caused Motion, but conflates motion with Deixis and spells out Path and Manner separately in intransitive clauses for spontaneous motion. Children learningEnglish and Korean show sensitivity to language-specific patterns in the way they talk about motion from as early as 17–20 months. For example, learners of English quickly generalize their earliest spatial words — Path particles like up, down, and in — to both spontaneous and caused changes of location and, for up and down, to posture changes, while learners of Korean keep words for spontaneous and caused motion strictly separate and use different words for vertical changes of location and posture changes. These findings challenge the widespread view that children initially map spatial words directly to nonlinguistic spatial concepts, and suggest that they are influenced by the semantic organization of their language virtually from the beginning. We discuss how input and cognition may interact in the early phases of learning to talk about space.
  • Clahsen, H., Prüfert, P., Eisenbeiss, S., & Cholin, J. (2002). Strong stems in the German mental lexicon: Evidence from child language acquisition and adult processing. In I. Kaufmann, & B. Stiebels (Eds.), More than words. Festschrift for Dieter Wunderlich (pp. 91-112). Berlin: Akadamie Verlag.
  • Clahsen, H., Eisenbeiss, S., Hadler, M., & Sonnenstuhl, I. (2001). The Mental Representation of Inflected Words: An Experimental Study of Adjectives and Verbs in German. Language, 77(3), 510-534. doi:10.1353/lan.2001.0140.

    Abstract

    The authors investigate how morphological relationships between inflected word forms are represented in the mental lexicon, focusing on paradigmatic relations between regularly inflected word forms and relationships between different stem forms of the same lexeme. We present results from a series of psycholinguistic experiments investigating German adjectives (which are inflected for case, number, and gender) and the so-called strong verbs of German, which have different stem forms when inflected for person, number, tense, or mood. Evidence from three lexical-decision experiments indicates that regular affixes are stripped off from their stems for processing purposes. It will be shown that this holds for both unmarked and marked stem forms. Another set of experiments revealed priming effects between different paradigmatically related affixes and between different stem forms of the same lexeme. We will show that associative models of inflection do not capture these findings, and we explain our results in terms of combinatorial models of inflection in which regular affixes are represented in inflectional paradigms and stem variants are represented in structured lexical entries. We will also argue that the morphosyntactic features of stems and affixes form abstract underspecified entries. The experimental results indicate that the human language processor makes use of these representations.

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  • Collins, J. (2015). ‘Give’ and semantic maps. In B. Nolan, G. Rawoens, & E. Diedrichsen (Eds.), Causation, permission, and transfer: Argument realisation in GET, TAKE, PUT, GIVE and LET verbs (pp. 129-146). Amsterdam: John Benjamins.
  • Collins, J. (2024). Linguistic areas and prehistoric migrations. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Cooper, N., Cutler, A., & Wales, R. (2002). Constraints of lexical stress on lexical access in English: Evidence from native and non-native listeners. Language and Speech, 45(3), 207-228.

    Abstract

    Four cross-modal priming experiments and two forced-choice identification experiments investigated the use of suprasegmental cues to stress in the recognition of spoken English words, by native (English-speaking) and non- native (Dutch) listeners. Previous results had indicated that suprasegmental information was exploited in lexical access by Dutch but not by English listeners. For both listener groups, recognition of visually presented target words was faster, in comparison to a control condition, after stress-matching spoken primes, either monosyllabic (mus- from MUsic /muSEum) or bisyl labic (admi- from ADmiral/admiRAtion). For native listeners, the effect of stress-mismatching bisyllabic primes was not different from that of control primes, but mismatching monosyllabic primes produced partial facilitation. For non-native listeners, both bisyllabic and monosyllabic stress-mismatching primes produced partial facilitation. Native English listeners thus can exploit suprasegmental information in spoken-word recognition, but information from two syllables is used more effectively than information from one syllable. Dutch listeners are less proficient at using suprasegmental information in English than in their native language, but, as in their native language, use mono- and bisyllabic information to an equal extent. In forced-choice identification, Dutch listeners outperformed native listeners at correctly assigning a monosyllabic fragment (e.g., mus-) to one of two words differing in stress.
  • Cooper, A., Brouwer, S., & Bradlow, A. R. (2015). Interdependent processing and encoding of speech and concurrent background noise. Attention, Perception & Psychophysics, 77(4), 1342-1357. doi:10.3758/s13414-015-0855-z.

    Abstract

    Speech processing can often take place in adverse listening conditions that involve the mixing of speech and background noise. In this study, we investigated processing dependencies between background noise and indexical speech features, using a speeded classification paradigm (Garner, 1974; Exp. 1), and whether background noise is encoded and represented in memory for spoken words in a continuous recognition memory paradigm (Exp. 2). Whether or not the noise spectrally overlapped with the speech signal was also manipulated. The results of Experiment 1 indicated that background noise and indexical features of speech (gender, talker identity) cannot be completely segregated during processing, even when the two auditory streams are spectrally nonoverlapping. Perceptual interference was asymmetric, whereby irrelevant indexical feature variation in the speech signal slowed noise classification to a greater extent than irrelevant noise variation slowed speech classification. This asymmetry may stem from the fact that speech features have greater functional relevance to listeners, and are thus more difficult to selectively ignore than background noise. Experiment 2 revealed that a recognition cost for words embedded in different types of background noise on the first and second occurrences only emerged when the noise and the speech signal were spectrally overlapping. Together, these data suggest integral processing of speech and background noise, modulated by the level of processing and the spectral separation of the speech and noise.
  • Coopmans, C. W., Mai, A., & Martin, A. E. (2024). “Not” in the brain and behavior. PLOS Biology, 22: e3002656. doi:10.1371/journal.pbio.3002656.
  • Coridun, S., Ernestus, M., & Ten Bosch, L. (2015). Learning pronunciation variants in a second language: Orthographic effects. In Scottish consortium for ICPhS 2015, M. Wolters, J. Livingstone, B. Beattie, R. Smith, M. MacMahon, J. Stuart-Smith, & J. Scobbie (Eds.), Proceedings of the 18th International Congress of Phonetic Sciences (ICPhS 2015). Glasgow: University of Glasgow.

    Abstract

    The present study investigated the effect of orthography on the learning and subsequent processing of pronunciation variants in a second language. Dutch learners of French learned reduced pronunciation variants that result from schwa-zero alternation in French (e.g., reduced /ʃnij/ from chenille 'caterpillar'). Half of the participants additionally learnt the words' spellings, which correspond more closely to the full variants with schwa. On the following day, participants performed an auditory lexical decision task, in which they heard half of the words in their reduced variants, and the other half in their full variants. Participants who had exclusively learnt the auditory forms performed significantly worse on full variants than participants who had also learnt the spellings. This shows that learners integrate phonological and orthographic information to process pronunciation variants. There was no difference between both groups in their performances on reduced variants, suggesting that the exposure to spelling does not impede learners' processing of these variants.
  • Cornelis, S. S., IntHout, J., Runhart, E. H., Grunewald, O., Lin, S., Corradi, Z., Khan, M., Hitti-Malin, R. J., Whelan, L., Farrar, G. J., Sharon, D., Van den Born, L. I., Arno, G., Simcoe, M., Michaelides, M., Webster, A. R., Roosing, S., Mahroo, O. A., Dhaenens, C.-M., Cremers, F. P. M. Cornelis, S. S., IntHout, J., Runhart, E. H., Grunewald, O., Lin, S., Corradi, Z., Khan, M., Hitti-Malin, R. J., Whelan, L., Farrar, G. J., Sharon, D., Van den Born, L. I., Arno, G., Simcoe, M., Michaelides, M., Webster, A. R., Roosing, S., Mahroo, O. A., Dhaenens, C.-M., Cremers, F. P. M., & ABCA4 Study Group (2024). Representation of women among individuals with mild variants in ABCA4-associated retinopathy: A meta-analysis. JAMA Ophthalmology, 142(5), 463-471. doi:10.1001/jamaophthalmol.2024.0660.

    Abstract

    Importance
    Previous studies indicated that female sex might be a modifier in Stargardt disease, which is an ABCA4-associated retinopathy.

    Objective
    To investigate whether women are overrepresented among individuals with ABCA4-associated retinopathy who are carrying at least 1 mild allele or carrying nonmild alleles.

    Data Sources
    Literature data, data from 2 European centers, and a new study. Data from a Radboudumc database and from the Rotterdam Eye Hospital were used for exploratory hypothesis testing.

    Study Selection
    Studies investigating the sex ratio in individuals with ABCA4-AR and data from centers that collected ABCA4 variant and sex data. The literature search was performed on February 1, 2023; data from the centers were from before 2023.

    Data Extraction and Synthesis
    Random-effects meta-analyses were conducted to test whether the proportions of women among individuals with ABCA4-associated retinopathy with mild and nonmild variants differed from 0.5, including subgroup analyses for mild alleles. Sensitivity analyses were performed excluding data with possibly incomplete variant identification. χ2 Tests were conducted to compare the proportions of women in adult-onset autosomal non–ABCA4-associated retinopathy and adult-onset ABCA4-associated retinopathy and to investigate if women with suspected ABCA4-associated retinopathy are more likely to obtain a genetic diagnosis. Data analyses were performed from March to October 2023.

    Main Outcomes and Measures
    Proportion of women per ABCA4-associated retinopathy group. The exploratory testing included sex ratio comparisons for individuals with ABCA4-associated retinopathy vs those with other autosomal retinopathies and for individuals with ABCA4-associated retinopathy who underwent genetic testing vs those who did not.

    Results
    Women were significantly overrepresented in the mild variant group (proportion, 0.59; 95% CI, 0.56-0.62; P < .001) but not in the nonmild variant group (proportion, 0.50; 95% CI, 0.46-0.54; P = .89). Sensitivity analyses confirmed these results. Subgroup analyses on mild variants showed differences in the proportions of women. Furthermore, in the Radboudumc database, the proportion of adult women among individuals with ABCA4-associated retinopathy (652/1154 = 0.56) was 0.10 (95% CI, 0.05-0.15) higher than among individuals with other retinopathies (280/602 = 0.47).

    Conclusions and Relevance
    This meta-analysis supports the likelihood that sex is a modifier in developing ABCA4-associated retinopathy for individuals with a mild ABCA4 allele. This finding may be relevant for prognosis predictions and recurrence risks for individuals with ABCA4-associated retinopathy. Future studies should further investigate whether the overrepresentation of women is caused by differences in the disease mechanism, by differences in health care–seeking behavior, or by health care discrimination between women and men with ABCA4-AR.
  • Corps, R. E., & Pickering, M. (2024). Response planning during question-answering: Does deciding what to say involve deciding how to say it? Psychonomic Bulletin & Review, 31, 839-848. doi:10.3758/s13423-023-02382-3.

    Abstract

    To answer a question, speakers must determine their response and formulate it in words. But do they decide on a response before formulation, or do they formulate different potential answers before selecting one? We addressed this issue in a verbal question-answering experiment. Participants answered questions more quickly when they had one potential answer (e.g., Which tourist attraction in Paris is very tall?) than when they had multiple potential answers (e.g., What is the name of a Shakespeare play?). Participants also answered more quickly when the set of potential answers were on average short rather than long, regardless of whether there was only one or multiple potential answers. Thus, participants were not affected by the linguistic complexity of unselected but plausible answers. These findings suggest that participants select a single answer before formulation.
  • Croijmans, I., & Majid, A. (2015). Odor naming is difficult, even for wine and coffee experts. In D. C. Noelle, R. Dale, A. S. Warlaumont, J. Yoshimi, T. Matlock, C. D. Jennings, & P. P. Maglio (Eds.), Proceedings of the 37th Annual Meeting of the Cognitive Science Society (CogSci 2015) (pp. 483-488). Austin, TX: Cognitive Science Society. Retrieved from https://mindmodeling.org/cogsci2015/papers/0092/index.html.

    Abstract

    Odor naming is difficult for people, but recent cross-cultural research suggests this difficulty is culture-specific. Jahai speakers (hunter-gatherers from the Malay Peninsula) name odors as consistently as colors, and much better than English speakers (Majid & Burenhult, 2014). In Jahai the linguistic advantage for smells correlates with a cultural interest in odors. Here we ask whether sub-cultures in the West with odor expertise also show superior odor naming. We tested wine and coffee experts (who have specialized odor training) in an odor naming task. Both wine and coffee experts were no more accurate or consistent than novices when naming odors. Although there were small differences in naming strategies, experts and non-experts alike relied overwhelmingly on source-based descriptions. So the specific language experts speak continues to constrain their ability to express odors. This suggests expertise alone is not sufficient to overcome the limits of language in the domain of smell.
  • Cronin, K. A., De Groot, E., & Stevens, J. M. G. (2015). Bonobos show limited social tolerance in a group setting: A comparison with chimpanzees and a test of the Relational Model. Folia primatologica, 86, 164-177. doi:10.1159/000373886.

    Abstract

    Social tolerance is a core aspect of primate social relationships with implications for the evolution of cooperation, prosociality and social learning. We measured the social tolerance of bonobos in an experiment recently validated with chimpanzees to allow for a comparative assessment of group-level tolerance, and found that the bonobo group studied here exhibited lower social tolerance on average than chimpanzees. Furthermore, following the Relational Model [de Waal, 1996], we investigated whether bonobos responded to an increased potential for social conflict with tolerance, conflict avoidance or conflict escalation, and found that only behaviours indicative of conflict escalation differed across conditions. Taken together, these findings contribute to the current debate over the level of social tolerance of bonobos and lend support to the position that the social tolerance of bonobos may not be notably high compared with other primates.
  • Cronin, K. A., Acheson, D. J., Hernández, P., & Sánchez, A. (2015). Hierarchy is Detrimental for Human Cooperation. Scientific Reports, 5: 18634. doi:10.1038/srep18634.

    Abstract

    Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species.
  • Cutler, A. (2002). Phonological processing: Comments on Pierrehumbert, Moates et al., Kubozono, Peperkamp & Dupoux, and Bradlow. In C. Gussenhoven, & N. Warner (Eds.), Papers in Laboratory Phonology VII (pp. 275-296). Berlin: Mouton de Gruyter.
  • Cutler, A., & Otake, T. (2002). Rhythmic categories in spoken-word recognition. Journal of Memory and Language, 46(2), 296-322. doi:10.1006/jmla.2001.2814.

    Abstract

    Rhythmic categories such as morae in Japanese or stress units in English play a role in the perception of spoken
    language. We examined this role in Japanese, since recent evidence suggests that morae may intervene as
    structural units in word recognition. First, we found that traditional puns more often substituted part of a mora
    than a whole mora. Second, when listeners reconstructed distorted words, e.g. panorama from panozema, responses
    were faster and more accurate when only a phoneme was distorted (panozama, panorema) than when a
    whole CV mora was distorted (panozema). Third, lexical decisions on the same nonwords were better predicted
    by duration and number of phonemes from nonword uniqueness point to word end than by number of morae. Our
    results indicate no role for morae in early spoken-word processing; we propose that rhythmic categories constrain
    not initial lexical activation but subsequent processes of speech segmentation and selection among word candidates.
  • Cutler, A., & Norris, D. (2002). The role of strong syllables in segmentation for lexical access. In G. T. Altmann (Ed.), Psycholinguistics: Critical concepts in psychology (pp. 157-177). London: Routledge.
  • Cutler, A., Mehler, J., Norris, D., & Segui, J. (2002). The syllable's differing role in the segmentation of French and English. In G. T. Altmann (Ed.), Psycholinguistics: Critical concepts in psychology (pp. 115-135). London: Routledge.

    Abstract

    Speech segmentation procedures may differ in speakers of different languages. Earlier work based on French speakers listening to French words suggested that the syllable functions as a segmentation unit in speech processing. However, while French has relatively regular and clearly bounded syllables, other languages, such as English, do not. No trace of syllabifying segmentation was found in English listeners listening to English words, French words, or nonsense words. French listeners, however, showed evidence of syllabification even when they were listening to English words. We conclude that alternative segmentation routines are available to the human language processor. In some cases speech segmentation may involve the operation of more than one procedure.
  • Cutler, A., McQueen, J. M., Jansonius, M., & Bayerl, S. (2002). The lexical statistics of competitor activation in spoken-word recognition. In C. Bow (Ed.), Proceedings of the 9th Australian International Conference on Speech Science and Technology (pp. 40-45). Canberra: Australian Speech Science and Technology Association (ASSTA).

    Abstract

    The Possible Word Constraint is a proposed mechanism whereby listeners avoid recognising words spuriously embedded in other words. It applies to words leaving a vowelless residue between their edge and the nearest known word or syllable boundary. The present study tests the usefulness of this constraint via lexical statistics of both English and Dutch. The analyses demonstrate that the constraint removes a clear majority of embedded words in speech, and thus can contribute significantly to the efficiency of human speech recognition
  • Cutler, A., Demuth, K., & McQueen, J. M. (2002). Universality versus language-specificity in listening to running speech. Psychological Science, 13(3), 258-262. doi:10.1111/1467-9280.00447.

    Abstract

    Recognizing spoken language involves automatic activation of multiple candidate words. The process of selection between candidates is made more efficient by inhibition of embedded words (like egg in beg) that leave a portion of the input stranded (here, b). Results from European languages suggest that this inhibition occurs when consonants are stranded but not when syllables are stranded. The reason why leftover syllables do not lead to inhibition could be that in principle they might themselves be words; in European languages, a syllable can be a word. In Sesotho (a Bantu language), however, a single syllable cannot be a word. We report that in Sesotho, word recognition is inhibited by stranded consonants, but stranded monosyllables produce no more difficulty than stranded bisyllables (which could be Sesotho words). This finding suggests that the viability constraint which inhibits spurious embedded word candidates is not sensitive to language-specific word structure, but is universal.
  • Cutler, A., & Fear, B. D. (1991). Categoricality in acceptability judgements for strong versus weak vowels. In J. Llisterri (Ed.), Proceedings of the ESCA Workshop on Phonetics and Phonology of Speaking Styles (pp. 18.1-18.5). Barcelona, Catalonia: Universitat Autonoma de Barcelona.

    Abstract

    A distinction between strong and weak vowels can be drawn on the basis of vowel quality, of stress, or of both factors. An experiment was conducted in which sets of contextually matched word-intial vowels ranging from clearly strong to clearly weak were cross-spliced, and the naturalness of the resulting words was rated by listeners. The ratings showed that in general cross-spliced words were only significantly less acceptable than unspliced words when schwa was not involved; this supports a categorical distinction based on vowel quality.
  • Cutler, A., Mehler, J., Norris, D., & Segui, J. (1983). A language-specific comprehension strategy [Letters to Nature]. Nature, 304, 159-160. doi:10.1038/304159a0.

    Abstract

    Infants acquire whatever language is spoken in the environment into which they are born. The mental capability of the newborn child is not biased in any way towards the acquisition of one human language rather than another. Because psychologists who attempt to model the process of language comprehension are interested in the structure of the human mind, rather than in the properties of individual languages, strategies which they incorporate in their models are presumed to be universal, not language-specific. In other words, strategies of comprehension are presumed to be characteristic of the human language processing system, rather than, say, the French, English, or Igbo language processing systems. We report here, however, on a comprehension strategy which appears to be used by native speakers of French but not by native speakers of English.
  • Cutler, A. (1985). Cross-language psycholinguistics. Linguistics, 23, 659-667.
  • Cutler, A. (2001). De baby in je hoofd: luisteren naar eigen en andermans taal [Speech at the Catholic University's 78th Dies Natalis]. Nijmegen, The Netherlands: Nijmegen University Press.
  • Cutler, A. (2001). Entries on: Acquisition of language by non-human primates; bilingualism; compound (linguistic); development of language-specific phonology; gender (linguistic); grammar; infant speech perception; language; lexicon; morphology; motor theory of speech perception; perception of second languages; phoneme; phonological store; phonology; prosody; sign language; slips of the tongue; speech perception; speech production; stress (linguistic); syntax; word recognition; words. In P. Winn (Ed.), Dictionary of biological psychology. London: Routledge.
  • Cutler, A. (2002). Lexical access. In L. Nadel (Ed.), Encyclopedia of cognitive science (pp. 858-864). London: Nature Publishing Group.
  • Cutler, A., McQueen, J. M., Norris, D., & Somejuan, A. (2002). Le rôle de la syllable. In E. Dupoux (Ed.), Les langages du cerveau: Textes en l’honneur de Jacques Mehler (pp. 185-197). Paris: Odile Jacob.
  • Cutler, A. (2002). Native listeners. European Review, 10(1), 27-41. doi:10.1017/S1062798702000030.

    Abstract

    Becoming a native listener is the necessary precursor to becoming a native speaker. Babies in the first year of life undertake a remarkable amount of work; by the time they begin to speak, they have perceptually mastered the phonological repertoire and phoneme co-occurrence probabilities of the native language, and they can locate familiar word-forms in novel continuous-speech contexts. The skills acquired at this early stage form a necessary part of adult listening. However, the same native listening skills also underlie problems in listening to a late-acquired non-native language, accounting for why in such a case listening (an innate ability) is sometimes paradoxically more difficult than, for instance, reading (a learned ability).
  • Cutler, A. (1982). Idioms: the older the colder. Linguistic Inquiry, 13(2), 317-320. Retrieved from http://www.jstor.org/stable/4178278?origin=JSTOR-pdf.
  • Cutler, A. (1983). Lexical complexity and sentence processing. In G. B. Flores d'Arcais, & R. J. Jarvella (Eds.), The process of language understanding (pp. 43-79). Chichester, Sussex: Wiley.
  • Cutler, A. (2015). Lexical stress in English pronunciation. In M. Reed, & J. M. Levis (Eds.), The Handbook of English Pronunciation (pp. 106-124). Chichester: Wiley.
  • Cutler, A., Mehler, J., Norris, D., & Segui, J. (1988). Limits on bilingualism [Letters to Nature]. Nature, 340, 229-230. doi:10.1038/340229a0.

    Abstract

    SPEECH, in any language, is continuous; speakers provide few reliable cues to the boundaries of words, phrases, or other meaningful units. To understand speech, listeners must divide the continuous speech stream into portions that correspond to such units. This segmentation process is so basic to human language comprehension that psycholinguists long assumed that all speakers would do it in the same way. In previous research1,2, however, we reported that segmentation routines can be language-specific: speakers of French process spoken words syllable by syllable, but speakers of English do not. French has relatively clear syllable boundaries and syllable-based timing patterns, whereas English has relatively unclear syllable boundaries and stress-based timing; thus syllabic segmentation would work more efficiently in the comprehension of French than in the comprehension of English. Our present study suggests that at this level of language processing, there are limits to bilingualism: a bilingual speaker has one and only one basic language.
  • Cutler, A. (1991). Linguistic rhythm and speech segmentation. In J. Sundberg, L. Nord, & R. Carlson (Eds.), Music, language, speech and brain (pp. 157-166). London: Macmillan.
  • Cutler, A. (2001). Listening to a second language through the ears of a first. Interpreting, 5, 1-23.
  • Cutler, A., & Pearson, M. (1985). On the analysis of prosodic turn-taking cues. In C. Johns-Lewis (Ed.), Intonation in discourse (pp. 139-155). London: Croom Helm.
  • Cutler, A., & Fay, D. A. (1982). One mental lexicon, phonologically arranged: Comments on Hurford’s comments. Linguistic Inquiry, 13, 107-113. Retrieved from http://www.jstor.org/stable/4178262.
  • Cutler, A. (1985). Performance measures of lexical complexity. In G. Hoppenbrouwers, P. A. Seuren, & A. Weijters (Eds.), Meaning and the lexicon (pp. 75). Dordrecht: Foris.
  • Cutler, A. (1991). Proceed with caution. New Scientist, (1799), 53-54.
  • Cutler, A. (1982). Prosody and sentence perception in English. In J. Mehler, E. C. Walker, & M. Garrett (Eds.), Perspectives on mental representation: Experimental and theoretical studies of cognitive processes and capacities (pp. 201-216). Hillsdale, N.J: Erlbaum.
  • Cutler, A. (1991). Prosody in situations of communication: Salience and segmentation. In Proceedings of the Twelfth International Congress of Phonetic Sciences: Vol. 1 (pp. 264-270). Aix-en-Provence: Université de Provence, Service des publications.

    Abstract

    Speakers and listeners have a shared goal: to communicate. The processes of speech perception and of speech production interact in many ways under the constraints of this communicative goal; such interaction is as characteristic of prosodic processing as of the processing of other aspects of linguistic structure. Two of the major uses of prosodic information in situations of communication are to encode salience and segmentation, and these themes unite the contributions to the symposium introduced by the present review.
  • Cutler, A., & Ladd, D. R. (Eds.). (1983). Prosody: Models and measurements. Heidelberg: Springer.
  • Cutler, A. (2015). Representation of second language phonology. Applied Psycholinguistics, 36(1), 115-128. doi:10.1017/S0142716414000459.

    Abstract

    Orthographies encode phonological information only at the level of words (chiefly, the information encoded concerns phonetic segments; in some cases, tonal information or default stress may be encoded). Of primary interest to second language (L2) learners is whether orthography can assist in clarifying L2 phonological distinctions that are particularly difficult to perceive (e.g., where one native-language phonemic category captures two L2 categories). A review of spoken-word recognition evidence suggests that orthographic information can install knowledge of such a distinction in lexical representations but that this does not affect learners’ ability to perceive the phonemic distinction in speech. Words containing the difficult phonemes become even harder for L2 listeners to recognize, because perception maps less accurately to lexical content.
  • Cutler, A. (1983). Semantics, syntax and sentence accent. In M. Van den Broecke, & A. Cohen (Eds.), Proceedings of the Tenth International Congress of Phonetic Sciences (pp. 85-91). Dordrecht: Foris.
  • Cutler, A. (Ed.). (1982). Slips of the tongue and language production. The Hague: Mouton.
  • Cutler, A. (1983). Speakers’ conceptions of the functions of prosody. In A. Cutler, & D. R. Ladd (Eds.), Prosody: Models and measurements (pp. 79-91). Heidelberg: Springer.
  • Cutler, A. (1982). Speech errors: A classified bibliography. Bloomington: Indiana University Linguistics Club.
  • Cutler, A. (1988). The perfect speech error. In L. Hyman, & C. Li (Eds.), Language, speech and mind: Studies in honor of Victoria A. Fromkin (pp. 209-223). London: Croom Helm.
  • Cutler, A., & Norris, D. (1988). The role of strong syllables in segmentation for lexical access. Journal of Experimental Psychology: Human Perception and Performance, 14, 113-121. doi:10.1037/0096-1523.14.1.113.

    Abstract

    A model of speech segmentation in a stress language is proposed, according to which the occurrence of a strong syllable triggers segmentation of the speech signal, whereas occurrence of a weak syllable does not trigger segmentation. We report experiments in which listeners detected words embedded in nonsense bisyllables more slowly when the bisyllable had two strong syllables than when it had a strong and a weak syllable; mint was detected more slowly in mintayve than in mintesh. According to our proposed model, this result is an effect of segmentation: When the second syllable is strong, it is segmented from the first syllable, and successful detection of the embedded word therefore requires assembly of speech material across a segmentation position. Speech recognition models involving phonemic or syllabic recoding, or based on strictly left-to-right processes, do not predict this result. It is argued that segmentation at strong syllables in continuous speech recognition serves the purpose of detecting the most efficient locations at which to initiate lexical access. (C) 1988 by the American Psychological Association

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