Publications

Abstract

Encoding the temporal properties of external signals that comprise multimodal events is a major factor guiding everyday experience. However, during the natural aging process, impairments to sensory processing can profoundly affect multimodal temporal perception. Various mechanisms can contribute to temporal perception, and thus it is imperative to understand how each can be affected by age. In the current study, using three different temporal order judgement tasks (unisensory, multisensory, and sensorimotor), we investigated the effects of age on two separate temporal processes: synchronization and integration of multiple signals. These two processes rely on different aspects of temporal information, either the temporal alignment of processed signals or the integration/segregation of signals arising from different modalities, respectively. Results showed that the ability to integrate/segregate multiple signals decreased with age regardless of the task, and that the magnitude of such impairment correlated across tasks, suggesting a widespread mechanism affected by age. In contrast, perceptual synchrony remained stable with age, revealing a distinct intact mechanism. Overall, results from this study suggest that aging has differential effects on temporal processing, and general impairments with aging may impact global temporal sensitivity while context-dependent processes remain unaffected.

Abstract

Behavioral syntactic priming effects during sentence comprehension are typically observed only if both the syntactic structure and lexical head are repeated. In contrast, during production syntactic priming occurs with structure repetition alone, but the effect is boosted by repetition of the lexical head. We used fMRI to investigate the neuronal correlates of syntactic priming and lexical boost effects during sentence production and comprehension. The critical measure was the magnitude of fMRI adaptation to repetition of sentences in active or passive voice, with or without verb repetition. In conditions with repeated verbs, we observed adaptation to structure repetition in the left IFG and MTG, for active and passive voice. However, in the absence of repeated verbs, adaptation occurred only for passive sentences. None of the fMRI adaptation effects yielded differential effects for production versus comprehension, suggesting that sentence comprehension and production are subserved by the same neuronal infrastructure for syntactic processing.

Abstract

Repetition suppression in fMRI studies is generally thought to underlie behavioural facilitation effects (i.e., priming) and it is often used to identify the neuronal representations associated with a stimulus. However, this pays little heed to the large number of repetition enhancement effects observed under similar conditions. In this review, we identify several cognitive variables biasing repetition effects in the BOLD response towards enhancement instead of suppression. These variables are stimulus recognition, learning, attention, expectation and explicit memory. We also evaluate which models can account for these repetition effects and come to the conclusion that there is no one single model that is able to embrace all repetition enhancement effects. Accumulation, novel network formation as well as predictive coding models can all explain subsets of repetition enhancement effects.

Abstract

Like every other social sphere, science is influenced by individual characteristics of researchers. However, for investigations on scientific networks, only little data about the social background of researchers, e.g. social origin, gender, affiliation etc., is available.
This paper introduces ”Take it personally - TIP”, a conceptual model and library currently under development, which aims to support the
semantic enrichment of publication databases with semantically related background information which resides elsewhere in the (semantic) web, such as Wikidata.
The supplementary information enriches the original information in the publication databases and thus facilitates the creation of complex scientific knowledge graphs. Such enrichment helps to improve the scientometric analysis of scientific publications as they can also take social backgrounds of researchers into account and to understand social structure in research communities.

Abstract

Feedforward deep convolutional neural networks (DCNNs) are matching and even surpassing human performance on object recognition. This performance suggests that activation of a loose collection of image
features could support the recognition of natural object categories, without dedicated systems to solve specific visual subtasks. Recent findings in humans however, suggest that while feedforward activity may suffice for
sparse scenes with isolated objects, additional visual operations ('routines') that aid the recognition process (e.g. segmentation or grouping) are needed for more complex scenes. Linking human visual processing to
performance of DCNNs with increasing depth, we here explored if, how, and when object information is differentiated from the backgrounds they appear on. To this end, we controlled the information in both objects
and backgrounds, as well as the relationship between them by adding noise, manipulating background congruence and systematically occluding parts of the image. Results indicated less distinction between object- and background features for more shallow networks. For those networks, we observed a benefit of training on segmented objects (as compared to unsegmented objects). Overall, deeper networks trained on natural
(unsegmented) scenes seem to perform implicit 'segmentation' of the objects from their background, possibly by improved selection of relevant features.

Abstract

People have stereotypes about gesture usage. For instance, speakers in East Asia are not supposed to gesticulate, and it is believed that Italians gesticulate more than the British. Despite the prevalence of such views, studies that investigate these stereotypes are scarce. The present study examined peopleÕs views on spontaneous gestures by collecting data from five different countries. A total of 363 undergraduate students from five countries (France, Italy, Japan, the Netherlands and USA) participated in this study. Data were collected through a two-part questionnaire. Part 1 asked participants to rate two characteristics of gesture: frequency and size of gesture for 13 different languages. Part 2 asked them about their views on factors that might affect the production of gestures. The results showed that most participants in this study believe that Italian, Spanish, and American English speakers produce larger gestures more frequently than other language speakers. They also showed that each culture group, even within Europe, put weight on a slightly different aspect of gestures.

Abstract

This study examined how well 5-, 6-, 10-year-olds and adults integrated information from spoken discourse with cohesive use of space in gesture, in comprehension. In Experiment 1, participants were presented with a combination of spoken discourse and a sequence of cohesive gestures, which consistently located each of the two protagonists in two distinct locations in gesture space. Participants were asked to select an interpretation of the final sentence that best matched the preceding spoken and gestural contexts. Adults and 10-year-olds performed better than 5-year-olds, who were at chance level. In Experiment 2, another group of 5-year-olds was presented with the same stimuli as in Experiment 1, except that the actor showed hand-held pictures, instead of producing cohesive gestures. Unlike cohesive gestures, one set of pictures was self-explanatory and did not require integration with the concurrent speech to derive the referent. With these pictures, 5-year-olds performed nearly perfectly and their performance in the identifiable pictures was significantly better than those in the unidentifiable pictures. These results suggest that young children failed to integrate spoken discourse and cohesive use of space in gestures, because they cannot derive a referent of cohesive gestures from the local speech context.

Abstract

Background: Gesture frequently accompanies speech in healthy speakers. For many individuals with aphasia, gestures are a target of speech-language pathology intervention, either as an alternative form of communication or as a facilitative device for language restoration. The patterns of gesture production for people with aphasia and the participant variables that predict these patterns remain unclear. Aims: We aimed to examine gesture production during conversational discourse in a large sample of individuals with aphasia. We used a detailed gesture coding system to determine patterns of gesture production associated with specific aphasia types and severities. Methods & Procedures: We analysed conversation samples from AphasiaBank, gathered from 46 people with post-stroke aphasia and 10 healthy matched controls all of whom had gestured at least once during a story re-tell task. Twelve gesture types were coded. Descriptive statistics were used to describe the patterns of gesture production. Possible significant differences in production patterns according to aphasia type and severity were examined with a series of analyses of variance (ANOVA) statistics, and multiple regression analysis was used to examine these potential predictors of gesture production patterns. Outcomes & Results: Individuals with aphasia gestured significantly more frequently than healthy controls. Aphasia type and severity impacted significantly on gesture type in specific identified patterns detailed here, especially on the production of meaning-laden gestures. Conclusions: These patterns suggest the opportunity for gestures as targets of aphasia therapy. Aphasia fluency accounted for a greater degree of data variability than aphasia severity or naming skills. More work is required to delineate predictive factors.

Abstract

We examined whether children's ability to integrate speech and gesture follows the pattern of a broader developmental shift between 3- and 5-year-old children (Ramscar & Gitcho, 2007) regarding the ability to process two pieces of information simultaneously. In Experiment 1, 3-year-olds, 5-year-olds, and adults were presented with either an iconic gesture or a spoken sentence or a combination of the two on a computer screen, and they were instructed to select a photograph that best matched the message. The 3-year-olds did not integrate information in speech and gesture, but 5-year-olds and adults did. In Experiment 2, 3-year-old children were presented with the same speech and gesture as in Experiment 1 that were produced live by an experimenter. When presented live, 3-year-olds could integrate speech and gesture. We concluded that development of the integration ability is a part of the broader developmental shift; however, live-presentation facilitates the nascent integration ability in 3-year-olds.

Abstract

We examined how two-handed gestures and speech with equivalent contents that are used in narrative develop during childhood. The participants were 40 native speakers of English consisting of four different age groups: 3-, 5-, 9-year-olds, and adults. A set of 10 video clips depicting motion events were used to elicit speech and gesture. There are two findings. First, two types of two-handed gestures showed different developmental changes: those with a single-handed stroke with a simultaneous hold increased with age, while those with a two handed-stroke decreased with age. Second, representational gesture and speech developed in parallel at the discourse level. More specifically, the ways in which information is packaged in a gesture and in a clause are similar for a given age group; that is, gesture and speech develop hand-in-hand.

Abstract

Purpose For many individuals with aphasia, gestures form a vital component of message transfer and are the target of speech-language pathology intervention. What remains unclear are the participant variables that predict successful outcomes from gesture treatments. The authors examined the gesture production of a large number of individuals with aphasia—in a consistent discourse sampling condition and with a detailed gesture coding system—to determine patterns of gesture production associated with specific types of aphasia. Method The authors analyzed story retell samples from AphasiaBank (TalkBank, n.d.), gathered from 98 individuals with aphasia resulting from stroke and 64 typical controls. Twelve gesture types were coded. Descriptive statistics were used to describe the patterns of gesture production. Possible significant differences in production patterns according to aphasia type were examined using a series of chi-square, Fisher exact, and logistic regression statistics. Results A significantly higher proportion of individuals with aphasia gestured as compared to typical controls, and for many individuals with aphasia, this gesture was iconic and was capable of communicative load. Aphasia type impacted significantly on gesture type in specific identified patterns, detailed here. Conclusion These type-specific patterns suggest the opportunity for gestures as targets of aphasia therapy.

Abstract

This article discusses how the Trobriand Islanders speak about body and mind. It addresses the following questions: do the linguistic datafit into theories about lexical universals of body-part terminology? Can we make inferences about the Trobrianders' conceptualization of psychological and physical states on the basis of these data? If a Trobriand Islander sees these idioms as external manifestations of inner states, then can we interpret them as a kind of ethnopsychological theory about the body and its role for emotions, knowledge, thought, memory, and so on? Can these idioms be understood as representation of Trobriand ethnopsychological theory?

Abstract

This volume presents 22 tales from the Trobriand Islands told by children (boys between the age of 5 and 9 years) and adults. The monograph is motivated not only by the anthropological linguistic aim to present a broad and quite unique collection of tales with the thematic approach to illustrate which topics and themes constitute the content of the stories, but also by the psycholinguistic and textlinguistic questions of how children acquire linearization and other narrative strategies, how they develop them and how they use them to structure these texts in an adult-like way. The tales are presented in morpheme-interlinear transcriptions with first textlinguistic analyses and cultural background information necessary to fully understand them. A summarizing comparative analysis of the texts from a psycholinguistic, anthropological linguistic and philological point of view discusses the underlying schemata of the stories, the means narrators use to structure them, their structural complexity and their cultural specificity. The e-book is made available under a CC BY-NC-ND 4.0 license.

Abstract

Die Sprachwissenschaft hat den Begriff und das Konzept ›Rituelle Kommunikation‹ von der vergleichenden Verhaltensforschung übernommen. Humanethologen unterscheiden eine Reihe von sogenannten ›Ausdrucksbewegungen‹, die in der Mimik, der Gestik, der Personaldistanz (Proxemik) und der Körperhaltung (Kinesik) zum Ausdruck kommen. Viele dieser Ausdrucksbewegungen haben sich zu spezifischen Signalen entwickelt. Ethologen definieren Ritualisierung als Veränderung von Verhaltensweisen im Dienst der Signalbildung. Die zu Signalen ritualisierten Verhaltensweisen sind Rituale. Im Prinzip kann jede Verhaltensweise zu einem Signal werden, entweder im Laufe der Evolution oder durch Konventionen, die in einer bestimmten Gemeinschaft gültig sind, die solche Signale kulturell entwickelt hat und die von ihren Mitgliedern tradiert und gelernt werden.

Abstract

This paper is an attempt to show that given the available observations on the behaviour of negation and presuppositions there is no simpler explanation than to assume that natural language has two distinct negation operators, the minimal negation which preserves presuppositions and the radical negation which does not. The three-valued logic emerging from this distinction, and especially its model-theory, are discussed in detail. It is, however, stressed that the logic itself is only epiphenomenal on the structures and processes involved in the interpretation of sentences. Horn (1985) brings new observations to bear, related with metalinguistic uses of negation, and proposes a “pragmatic” ambiguity in negation to the effect that in descriptive (or “straight”) use negation is the classical bivalent operator, whereas in metalinguistic use it is non-truthfunctional but only pragmatic. Van der Sandt (to appear) accepts Horn's observations but proposes a different solution: he proposes an ambiguity in the argument clause of the negation operator (which, for him, too, is classical and bivalent), according to whether the negation takes only the strictly asserted proposition or covers also the presuppositions, the (scalar) implicatures and other implications (in particular of style and register) of the sentence expressing that proposition. These theories are discussed at some length. The three-valued analysis is defended on the basis of partly new observations, which do not seem to fit either Horn's or Van der Sandt's solution. It is then placed in the context of incremental discourse semantics, where both negations are seen to do the job of keeping increments out of the discourse domain, though each does so in its own specific way. The metalinguistic character of the radical negation is accounted for in terms of the incremental apparatus. The metalinguistic use of negation in denials of implicatures or implications of style and register is regarded as a particular form of minimal negation, where the negation denies not the proposition itself but the appropriateness of the use of an expression in it. This appropriateness negation is truth-functional and not pragmatic, but it applies to a particular, independently motivated, analysis of the argument clause. The ambiguity of negation in natural language is different from the ordinary type of ambiguity found in the lexicon. Normally, lexical ambiguities are idiosyncratic, highly contingent, and unpredictable from language to language. In the case of negation, however, the two meanings are closely related, both truth-conditionally and incrementally. Moreover, the mechanism of discourse incrementation automatically selects the right meaning. These properties are taken to provide a sufficient basis for discarding the, otherwise valid, objection that negation is unlikely to be ambiguous because no known language makes a lexical distinction between the two readings.

Abstract

The message of the present article is, first, that, besides and below the strictly linguistic aspects of communication through language, of which speakers are in principle fully aware, a great deal of knowledge not carried in virtue of the system of the language in question but rather transmitted by the form of the intended message, is imparted to listeners or readers, without either being in the least aware of this happening. For example, listeners quickly register the social status, regional origin or emotional attitude of speakers and they react to those kinds of ‘paralinguistic’ information, mostly totally unawares. When speaker and listener have a positive attitude with regard to each other, the reaction consists, among other things, in mutual alignment or accommodation of pronunciation features, lexical selections and style of speaking. When the mutual attitude is negative, the opposite happens: speakers accentuate their differences. Then, when this happens not between individual interlocutors but between groups of speakers, such accommodation or divergence phenomena may lead to language change. The main theoretical question raised, but not answered, in this article is how and at what point forms of behaviour, including linguistic behaviour, achieve the status of being ‘standard’ or ‘accepted’ in any given community and what it means to say that they are ‘standard’ or ‘accepted’. It is argued that frequency of occurrence is not the main explanatory factor, and that a causal explanation is to be sought rather in the, often unconscious, attitudes of individuals, in particular their desire or need to be integrated members of a community or social group, thus ensuring their safety and asserting their group identity. The question thus belongs to the province of social psychology. Qualms about analyses of this kind being ‘unscientific’ dissipate when it is realized that consciousness phenomena are part of the real world and must therefore be considered to be valid objects of scientific theory formation. Like so many other ill-understood elements in scientific theories, consciousness, though itself unexplained, can be given a place in causal chains of events.

Abstract

The Open Access Movement promotes free and unfettered access to research publications and, increasingly, to the primary data which underly those publications. As the field of documentary linguistics seeks to record and preserve culturally and linguistically relevant materials, the question of how openly accessible these materials should be becomes increasingly important. This paper aims to guide researchers and other stakeholders in finding an appropriate balance between accessibility and confidentiality of data, addressing community questions and legal, institutional, and intellectual issues that pose challenges to accessible data.

Abstract

Autism spectrum disorder is increasingly associated with atypical perceptual and sensory symptoms. Here we explore the hypothesis
that aberrant sensory processing in autism spectrum disorder could be linked to atypical intra- (local) and interregional (global)
brain connectivity. To elucidate oscillatory dynamics and connectivity in the visual domain we used magnetoencephalography and
a simple visual grating paradigm with a group of 18 adolescent autistic participants and 18 typically developing control subjects.
Both groups showed similar increases in gamma (40–80 Hz) and decreases in alpha (8–13 Hz) frequency power in occipital cortex.
However, systematic group differences emerged when analysing intra- and interregional connectivity in detail. First, directed
connectivity was estimated using non-parametric Granger causality between visual areas V1 and V4. Feedforward V1-to-V4
connectivity, mediated by gamma oscillations, was equivalent between autism spectrum disorder and control groups, but importantly,
feedback V4-to-V1 connectivity, mediated by alpha (8–13 Hz) oscillations, was significantly reduced in the autism spectrum
disorder group. This reduction was positively correlated with autistic quotient scores, consistent with an atypical visual hierarchy
in autism, characterized by reduced top-down modulation of visual input via alpha-band oscillations. Second, at the local level in
V1, coupling of alpha-phase to gamma amplitude (alpha-gamma phase amplitude coupling) was reduced in the autism spectrum
disorder group. This implies dysregulated local visual processing, with gamma oscillations decoupled from patterns of wider alphaband
phase synchrony (i.e. reduced phase amplitude coupling), possibly due to an excitation-inhibition imbalance. More generally,
these results are in agreement with predictive coding accounts of neurotypical perception and indicate that visual processes in
autism are less modulated by contextual feedback information.

Abstract

Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric disorders. At present, the neural correlates of cognitive dysfunction across psychiatric disorders are poorly understood. The aim of this study was to investigate functional connectivity and structural perturbations across psychiatric diagnoses in three neurocognitive networks of interest, including the default-mode (DMN), the frontoparietal (FPN) and the salience network (SN). Methods We performed meta-analyses of resting-state functional MRI (R-fMRI) whole-brain seed-based functional connectivity in 8,298 patients (involving 8 disorders) and 8,165 healthy controls and a voxel-based morphometry analysis of structural MRI data in 14,027 patients (involving 8 disorders) and healthy 14,504 controls. To aid the interpretation of the results, we examined neurocognitive function in 776 healthy participants from the Human Connectome Project. Results We found that the three neurocognitive networks of interest were characterized by shared alterations of functional connectivity architecture across psychiatric disorders. More specifically, hypoconnectivity was expressed between the DMN and ventral SN and between the SN and FPN, whereas hyperconnectivity was evident between the DMN and FPN and between the DMN and dorsal SN. This pattern of network alterations was associated with gray matter reductions in patients, and was localized in regions that subserve general cognitive performance. Conclusions This study is the first to provide meta-analytic evidence of common alterations of functional connectivity within and between neurocognitive networks. The findings suggest a shared mechanism of network interactions that may associate with the generalized cognitive deficits observed in psychiatric disorders.

Abstract

There is mounting evidence that the ease of producing and understanding language depends not only on the frequencies of individual words but also on the frequencies of word combinations. However, in two picture description experiments, Janssen and Barber (2012) found that French and Spanish speakers' speech onset latencies for short phrases depended exclusively on the frequencies of the phrases but not on the frequencies of the individual words. They suggested that speakers retrieved phrase-sized units from the mental lexicon. In the present study, we examined whether the time required to plan complex noun phrases in Dutch would likewise depend only on phrase frequencies. Participants described line drawings in phrases such as rode schoen [red shoe] (Experiments 1 and 2) or de rode schoen [the red shoe] (Experiment 3). Replicating Janssen and Barber's findings, utterance onset latencies depended on the frequencies of the phrases but, deviating from their findings, also depended on the frequencies of the adjectives in adjective-noun phrases and the frequencies of the nouns in determiner-adjective-noun phrases. We conclude that individual word frequencies and phrase frequencies both affect the time needed to produce noun phrases and discuss how these findings may be captured in models of the mental lexicon and of phrase production

Abstract

The present study examined the relation between nonselective inhibition and selective inhibition in picture naming performance. Nonselective inhibition refers to the ability to suppress any unwanted response, whereas selective inhibition refers to the ability to suppress specific competing responses. The degree of competition in picture naming was manipulated by presenting targets along with distractor words that could be semantically related (e.g., a picture of a dog combined with the word cat) or unrelated (tree) to the picture name. The mean naming response time (RT) was longer in the related than in the unrelated condition, reflecting semantic interference. Delta plot analyses showed that participants with small mean semantic interference effects employed selective inhibition more effectively than did participants with larger semantic interference effects. The participants were also tested on the stop-signal task, which taps nonselective inhibition. Their performance on this task was correlated with their mean naming RT but, importantly, not with the selective inhibition indexed by the delta plot analyses and the magnitude of the semantic interference effect. These results indicate that nonselective inhibition ability and selective inhibition of competitors in picture naming are separable to some extent.

Abstract

In two studies, we examined whether explicit distractors are necessary and sufficient toevoke selective inhibition in three naming tasks: the semantic blocking, picture-word interference, and color-word Stroop task. Delta plots were used to quantify the size of the interference effects as a function of reaction time (RT). Selective inhibition was operationalized as the decrease in the size of the interference effect as a function of naming RT. For all naming tasks, mean naming RTs were significantly longer in the interference condition than in a control condition. The slopes of the interference effects for the longest naming RTs correlated with the magnitude of the mean interference effect in both the semantic blocking task and the picture-word interference task, suggesting that selective inhibition was involved to reduce the interference from strong semantic competitors either invoked by a single explicit competitor or strong implicit competitors in picture naming. However, there was no correlation between the slopes and the mean interference effect in the Stroop task, suggesting less importance of selective inhibition in this task despite explicit distractors. Whereas the results of the semantic blocking task suggest that an explicit distractor is not necessary for triggering inhibition, the results of the Stroop task suggest that such a distractor is not sufficient for evoking inhibition either.

Abstract

Interactions between top-down and bottom-up information streams are integral to brain function but challenging to measure noninvasively. Laminar resolution, functional MRI (lfMRI) is sensitive to depth-dependent properties of the blood oxygen level-dependent (BOLD) response, which can be potentially related to top-down and bottom-up signal contributions. In this work, we used lfMRI to dissociate the top-down and bottom-up signal contributions to the left occipitotemporal sulcus (LOTS) during word reading. We further demonstrate that laminar resolution measurements could be used to identify condition-specific distributed networks on the basis of whole-brain connectivity patterns specific to the depth-dependent BOLD signal. The networks corresponded to top-down and bottom-up signal pathways targeting the LOTS during word reading. We show that reading increased the top-down BOLD signal observed in the deep layers of the LOTS and that this signal uniquely related to the BOLD response in other language-critical regions. These results demonstrate that lfMRI can reveal important patterns of activation that are obscured at standard resolution. In addition to differences in activation strength as a function of depth, we also show meaningful differences in the interaction between signals originating from different depths both within a region and with the rest of the brain. We thus show that lfMRI allows the noninvasive measurement of directed interaction between brain regions and is capable of resolving different connectivity patterns at submillimeter resolution, something previously considered to be exclusively in the domain of invasive recordings.

Abstract

ndividual talkers may use various strategies to enrich their speech while speaking in noise (i.e., Lombard speech) to improve their intelligibility. The resulting acoustic-phonetic changes in Lombard speech vary amongst different speakers, but it is unclear what causes these talker differences, and what impact these differences have on intelligibility. This study investigates the potential role of articulatory control in talkers’ Lombard speech enrichment success. Seventy-eight speakers read out sentences in both their habitual style and in a condition where they were instructed to speak clearly while hearing loud speech-shaped noise. A diadochokinetic (DDK) speech task that requires speakers to repetitively produce word or non-word sequences as accurately and as rapidly as possible, was used to quantify their articulatory control. Individuals’ predicted intelligibility in both speaking styles (presented at -5 dB SNR) was measured using an acoustic glimpse-based metric: the High-Energy Glimpse Proportion (HEGP). Speakers’ HEGP scores show a clear effect of speaking condition (better HEGP scores in the Lombard than habitual condition), but no simple effect of articulatory control on HEGP, nor an interaction between speaking condition and articulatory control. This indicates that individuals’ speech enrichment success as measured by the HEGP metric was not predicted by DDK performance.

Abstract

In conversation, the initial pitch of an utterance can provide an early phonetic cue of the communicative function, the speech act, or the social action being implemented. We conducted quantitative acoustic measurements and statistical analyses of pitch in over 10,000 utterances, including 2512 questions, their responses, and about 5000 other utterances by 180 total speakers from a corpus of 70 natural conversations in 10 languages. We measured pitch at first prominence in a speaker’s utterance and discriminated utterances by language, speaker, gender, question form, and what social action is achieved by the speaker’s turn. Through applying multivariate logistic regression we found that initial pitch that significantly deviated from the speaker’s median pitch level was predictive of the social action of the question. In questions designed to solicit agreement with an evaluation rather than information, pitch was divergent from a speaker’s median predictably in the top 10% of a speakers range. This latter finding reveals a kind of iconicity in the relationship between prosody and social action in which a marked pitch correlates with a marked social action. Thus, we argue that speakers rely on pitch to provide an early signal for recipients that the question is not to be interpreted through its literal semantics but rather through an inference.

Abstract

In this study, we explore the possibility to predict the semantic category of words from brain signals in a free word generation task. Participants produced single words from different semantic categories in a modified semantic fluency task. A Bayesian logistic regression classifier was trained to predict the semantic category of words from single-trial MEG data. Significant classification accuracies were achieved using sensor-level MEG time series at the time interval of conceptual preparation. Semantic category prediction was also possible using source-reconstructed time series, based on minimum norm estimates of cortical activity. Brain regions that contributed most to classification on the source level were identified. These were the left inferior frontal gyrus, left middle frontal gyrus, and left posterior middle temporal gyrus. Additionally, the temporal dynamics of brain activity underlying the semantic preparation during word generation was explored. These results provide important insights about central aspects of language production

Abstract

An exploratory genome-wide copy number variant (CNV) study was performed in 127 independent cases with specific language impairment (SLI), their first-degree relatives (385 individuals) and 269 population controls. Language-impaired cases showed an increased CNV burden in terms of the average number of events (11.28 vs 10.01, empirical P=0.003), the total length of CNVs (717 vs 513 Kb, empirical P=0.0001), the average CNV size (63.75 vs 51.6 Kb, empirical P=0.0005) and the number of genes spanned (14.29 vs 10.34, empirical P=0.0007) when compared with population controls, suggesting that CNVs may contribute to SLI risk. A similar trend was observed in first-degree relatives regardless of affection status. The increased burden found in our study was not driven by large or de novo events, which have been described as causative in other neurodevelopmental disorders. Nevertheless, de novo CNVs might be important on a case-by-case basis, as indicated by identification of events affecting relevant genes, such as ACTR2 and CSNK1A1, and small events within known micro-deletion/-duplication syndrome regions, such as chr8p23.1. Pathway analysis of the genes present within the CNVs of the independent cases identified significant overrepresentation of acetylcholine binding, cyclic-nucleotide phosphodiesterase activity and MHC proteins as compared with controls. Taken together, our data suggest that the majority of the risk conferred by CNVs in SLI is via common, inherited events within a ‘common disorder–common variant’ model. Therefore the risk conferred by CNVs will depend upon the combination of events inherited (both CNVs and SNPs), the genetic background of the individual and the environmental factors.

Abstract

Perceptual compensation for speaker vocal tract properties was investigated in four groups of listeners: native speakers of English and native speakers of Dutch, native speakers of Spanish with low proficiency in English, and Spanish-English bilinguals. Listeners categorized targets on a [sofo] to [sufu] continuum. Targets were preceded by sentences that were manipulated to have either a high or a low F1 contour. All listeners performed the categorization task for targets that were preceded by Spanish, English and Dutch precursors. Results show that listeners from each of the four language backgrounds compensate for speaker vocal tract properties regardless of language-specific vowel inventory properties. Listeners also compensate when they listen to stimuli in another language. The results suggest that patterns of compensation are mainly determined by auditory properties of precursor sentences.

Abstract

Listeners have to overcome variability of the speech signal that can arise, for example, because of differences in room acoustics, differences in speakers’ vocal tract properties, or idiosyncrasies in pronunciation. Two mechanisms that are involved in resolving such variation are perceptually contrastive effects that arise from surrounding acoustic context and lexically guided perceptual learning. Although both processes have been studied in great detail, little attention has been paid to how they operate relative to each other in speech perception. The present study set out to address this issue. The carrier parts of exposure stimuli of a classical perceptual learning experiment were spectrally filtered such that the acoustically ambiguous final fricatives sounded relatively more like the lexically intended sound (Experiment 1) or the alternative (Experiment 2). Perceptual learning was found only in the latter case. The findings show that perceptual contrast effects precede lexically guided perceptual learning, at least in terms of temporal order, and potentially in terms of cognitive processing levels as well

Abstract

One of the important challenges for the development of science communication concerns the current problems with the under-exposure of null results. I suggest that each article published in a top scientific journal can get tagged (online) with attempts to replicate. As such, a future reader of an article will also be able to see whether replications have been attempted and how these turned out. Editors and/or reviewers decide whether a replication is of sound quality. The authors of the main article have the option to review the replication and can provide a supplementary comment with each attempt that is added. After 5 or 10 years, and provided enough attempts to replicate, the authors of the main article get the opportunity to discuss/review their original study in light of the outcomes of the replications. This approach has two important strengths: 1) The approach would provide researchers with the opportunity to show that they deliver scientifically thorough work, but sometimes just fail to replicate the result that others have reported. This can be especially valuable for the career opportunities of promising young researchers; 2) perhaps even more important, the visibility of replications provides an important incentive for researchers to publish findings only if they are sure that their effects are reliable (and thereby reduce the influence of "experimenter degrees of freedom" or even outright fraud). The proposed approach will stimulate researchers to look beyond the point of publication of their studies.

Abstract

Three experiments investigated whether extrinsic vowel normalization takes place largely at a categorical or a precategorical level of processing. Traditional vowel normalization effects in categorization were replicated in Experiment 1: Vowels taken from an [ɪ]-[ε] continuum were more often interpreted as /ɪ/ (which has a low first formant, F (1)) when the vowels were heard in contexts that had a raised F (1) than when the contexts had a lowered F (1). This was established with contexts that consisted of only two syllables. These short contexts were necessary for Experiment 2, a discrimination task that encouraged listeners to focus on the perceptual properties of vowels at a precategorical level. Vowel normalization was again found: Ambiguous vowels were more easily discriminated from an endpoint [ε] than from an endpoint [ɪ] in a high-F (1) context, whereas the opposite was true in a low-F (1) context. Experiment 3 measured discriminability between pairs of steps along the [ɪ]-[ε] continuum. Contextual influences were again found, but without discrimination peaks, contrary to what was predicted from the same participants' categorization behavior. Extrinsic vowel normalization therefore appears to be a process that takes place at least in part at a precategorical processing level.

Abstract

The acoustic dimensions that distinguish speech sounds (like the vowel differences in “boot” and “boat”) also differentiate speakers’ voices. Therefore, listeners must normalize across speakers without losing linguistic information. Past behavioral work suggests an important role for auditory contrast enhancement in normalization: preceding context affects listeners’ perception of subsequent speech sounds. Here, using intracranial electrocorticography in humans, we investigate whether and how such context effects arise in auditory cortex. Participants identified speech sounds that were preceded by phrases from two different speakers whose voices differed along the same acoustic dimension as target words (the lowest resonance of the vocal tract). In every participant, target vowels evoke a speaker-dependent neural response that is consistent with the listener’s perception, and which follows from a contrast enhancement model. Auditory cortex processing thus displays a critical feature of normalization, allowing listeners to extract meaningful content from the voices of diverse speakers.

Abstract

The smooth transitions between turns in natural conversation suggest that speakers often begin to plan their utterances while listening to their interlocutor. The presented study investigates whether this is indeed the case and, if so, when utterance planning begins. Two hypotheses were contrasted: that speakers begin to plan their turn as soon as possible (in our experiments less than a second after the onset of the interlocutor’s turn), or that they do so close to the end of the interlocutor’s turn. Turn-taking was combined with a finger tapping task to measure variations in cognitive load. We assumed that the onset of speech planning in addition to listening would be accompanied by deterioration in tapping performance. Two picture description experiments were conducted. In both experiments there were three conditions: (1) Tapping and Speaking, where participants tapped a complex pattern while taking over turns from a pre-recorded speaker, (2) Tapping and Listening, where participants carried out the tapping task while overhearing two pre-recorded speakers, and (3) Speaking Only, where participants took over turns as in the Tapping and Speaking condition but without tapping. The experiments differed in the amount of tapping training the participants received at the beginning of the session. In Experiment 2, the participants’ eye-movements were recorded in addition to their speech and tapping. Analyses of the participants’ tapping performance and eye movements showed that they initiated the cognitively demanding aspects of speech planning only shortly before the end of the turn of the preceding speaker. We argue that this is a smart planning strategy, which may be the speakers’ default in many everyday situations.

Abstract

Introduction The ability to identify individuals at increased genetic risk for Alzheimer's disease (AD) may streamline biomarker and drug trials and aid clinical and personal decision making. Methods We evaluated the discriminative ability of a genetic risk score (GRS) covering 22 published genetic risk loci for AD in 1162 Flanders-Belgian AD patients and 1019 controls and assessed correlations with family history, onset age, and cerebrospinal fluid (CSF) biomarkers (Aβ1-42, T-Tau, P-Tau181P). Results A GRS including all single nucleotide polymorphisms (SNPs) and age-specific APOE ε4 weights reached area under the curve (AUC) 0.70, which increased to AUC 0.78 for patients with familial predisposition. Risk of AD increased with GRS (odds ratio, 2.32 (95% confidence interval 2.08-2.58 per unit; P < 1.0e-15). Onset age and CSF Aβ1-42 decreased with increasing GRS (Ponset-age = 9.0e-11; PAβ = 8.9e-7). Discussion The discriminative ability of this 22-SNP GRS is still limited, but these data illustrate that incorporation of age-specific weights improves discriminative ability. GRS-phenotype correlations highlight the feasibility of identifying individuals at highest susceptibility. © 2015 The Authors.

Abstract

Speakers adapt their speech and gestures in various ways for their audience. We investigated further whether they use
ostensive signals (eye gaze, ostensive speech (e.g. like this, this) or a combination of both) in relation to their gestures
when talking to different addressees, i.e., to another adult or a child in a multimodal demonstration task. While adults used
more eye gaze towards their gestures with other adults than with children, they were more likely to use combined
ostensive signals for children than for adults. Thus speakers mark the communicative relevance of their gestures with different types of ostensive signals and by taking different types of addressees into account.

Abstract

It is widely accepted that specific memory processes, such as serial-order memory, are involved in written language development and predictive of reading and spelling abilities. The reverse question, namely whether orthographic abilities also affect serial-order memory, has hardly been investigated. In the current study, we compared 20 illiterate people with a group of 20 literate matched controls on a verbal and a visuospatial version of the Hebb paradigm, measuring both short- and long-term serial-order memory abilities. We observed better short-term serial-recall performance for the literate compared with the illiterate people. This effect was stronger in the verbal than in the visuospatial modality, suggesting that the improved capacity of the literate group is a consequence of learning orthographic skills. The long-term consolidation of ordered information was comparable across groups, for both stimulus modalities. The implications of these findings for current views regarding the bi-directional interactions between memory and written language development are discussed.

Abstract

Spinocerebellar ataxia type 23 is caused by mutations in PDYN, which encodes the opioid neuropeptide precursor protein, prodynorphin. Prodynorphin is processed into the opioid peptides, α-neoendorphin, and dynorphins A and B, that normally exhibit opioid-receptor mediated actions in pain signalling and addiction. Dynorphin A is likely a mutational hotspot for spinocerebellar ataxia type 23 mutations, and in vitro data suggested that dynorphin A mutations lead to persistently elevated mutant peptide levels that are cytotoxic and may thus play a crucial role in the pathogenesis of spinocerebellar ataxia type 23. To further test this and study spinocerebellar ataxia type 23 in more detail, we generated a mouse carrying the spinocerebellar ataxia type 23 mutation R212W in PDYN. Analysis of peptide levels using a radioimmunoassay shows that these PDYNR212W mice display markedly elevated levels of mutant dynorphin A, which are associated with climber fibre retraction and Purkinje cell loss, visualized with immunohistochemical stainings. The PDYNR212W mice reproduced many of the clinical features of spinocerebellar ataxia type 23, with gait deficits starting at 3 months of age revealed by footprint pattern analysis, and progressive loss of motor coordination and balance at the age of 12 months demonstrated by declining performances on the accelerating Rotarod. The pathologically elevated mutant dynorphin A levels in the cerebellum coincided with transcriptionally dysregulated ionotropic and metabotropic glutamate receptors and glutamate transporters, and altered neuronal excitability. In conclusion, the PDYNR212W mouse is the first animal model of spinocerebellar ataxia type 23 and our work indicates that the elevated mutant dynorphin A peptide levels are likely responsible for the initiation and progression of the disease, affecting glutamatergic signalling, neuronal excitability, and motor performance. Our novel mouse model defines a critical role for opioid neuropeptides in spinocerebellar ataxia, and suggests that restoring the elevated mutant neuropeptide levels can be explored as a therapeutic intervention.

Abstract

Language-mediated visual attention describes the interaction of two fundamental components of the human cognitive system, language and vision. Within this paper we present an amodal shared resource model of language-mediated visual attention that offers a description of the information and processes involved in this complex multimodal behavior and a potential explanation for how this ability is acquired. We demonstrate that the model is not only sufficient to account for the experimental effects of Visual World Paradigm studies but also that these effects are emergent properties of the architecture of the model itself, rather than requiring separate information processing channels or modular processing systems. The model provides an explicit description of the connection between the modality-specific input from language and vision and the distribution of eye gaze in language-mediated visual attention. The paper concludes by discussing future applications for the model, specifically its potential for investigating the factors driving observed individual differences in language-mediated eye gaze.

Abstract

Recent empirical evidence suggests that language-mediated eye gaze is partly determined by level of formal literacy training. Huettig, Singh and Mishra (2011) showed that high-literate individuals' eye gaze was closely time locked to phonological overlap between a spoken target word and items presented in a visual display. In contrast, low-literate individuals' eye gaze was not related to phonological overlap, but was instead strongly influenced by semantic relationships between items. Our present study tests the hypothesis that this behavior is an emergent property of an increased ability to extract phonological structure from the speech signal, as in the case of high-literates, with low-literates more reliant on more coarse grained structure. This hypothesis was tested using a neural network model, that integrates linguistic information extracted from the speech signal with visual and semantic information within a central resource. We demonstrate that contrasts in fixation behavior similar to those observed between high and low literates emerge when models are trained on speech signals of contrasting granularity.

Abstract

A quantitative model of human categorization behavior is proposed, which can be applied to 4-alternative forced-choice categorization data involving two binary classifications. A number of processing dependencies between the two classifications are explicitly formulated, such as the dependence of the location, orientation, and steepness of the class boundary for one classification on the outcome of the other classification. The significance of various types of dependencies can be tested statistically. Analyses of a data set from the literature shows that interesting dependencies in human speech recognition can be uncovered using the model.

Abstract

Blindsight refers to the observation of residual visual abilities in the hemianopic field of patients without a functional V1. Given the within- and between-subject variability in the preserved abilities and the phenomenal experience of blindsight patients, the fine-grained description of the phenomenon is still debated. Here we tested a patient with established “perceptual” and “attentional” blindsight (c.f. Danckert and Rossetti, 2005). Using a pointing paradigm patient MS, who suffers from a complete left homonymous hemianopia, showed clear above chance manual localisation of ‘unseen’ targets. In addition, target presentations in his blind field led MS, on occasion, to spontaneous responses towards his sighted field. Structural and functional magnetic resonance imaging was conducted to evaluate the magnitude of V1 damage. Results revealed the presence of a calcarine sulcus in both hemispheres, yet his right V1 is reduced, structurally disconnected and shows no fMRI response to visual stimuli. Thus, visual stimulation of his blind field can lead to “action blindsight” and spontaneous antipointing, in absence of a functional right V1. With respect to the antipointing, we suggest that MS may have registered the stimulation and subsequently presumes it must have been in his intact half field.

Abstract

Previous research [9] suggests that Dutch learners of (British) English are not able to express sarcasm prosodically in their L2. The present study investigates whether explicit training on the prosodic markers of sarcasm in English can improve learners’ realisation of sarcasm. Sarcastic speech was elicited in short simulated telephone conversations between Dutch advanced learners of English and a native British English-speaking ‘friend’ in two sessions, fourteen days apart. Between the two sessions, participants were trained by means of (1) a presentation, (2) directed independent practice, and (3) evaluation of participants’ production and individual feedback in small groups. L1 British English-speaking raters subsequently evaluated the degree of sarcastic sounding in the participants’ responses on a five-point scale. It was found that significantly higher sarcasm ratings were given to L2 learners’ production obtained after the training than that obtained before the training; explicit training on prosody has a positive effect on learners’ production of sarcasm.

Abstract

Atypical visual perception in people with autism spectrum disorders (ASD) is hypothesized to stem from an imbalance in excitatory and inhibitory processes in the brain. We used neuronal oscillations in the gamma frequency range (30 – 90 Hz), which emerge from a balanced interaction of excitation and inhibition in the brain, to assess contextual modulation processes in early visual perception. Electroencephalography was recorded in 12 high-functioning adults with ASD and 12 age- and IQ-matched control participants. Oscilla- tions in the gamma frequency range were analyzed in response to stimuli consisting of small line-like elements. Orientation-speci fi c contextual modulation was manipulated by parametrically increasing the amount of homogeneously oriented elements in the stimuli. The stimuli elicited a strong steady-state gamma response around the refresh-rate of 60 Hz, which was larger for controls than for participants with ASD. The amount of orientation homogeneity (contextual modulation) in fl uenced the gamma response in control subjects, while for subjects with ASD this was not the case. The atypical steady-state gamma response to contextual modulation in subjects with ASD may capture the link between an imbalance in excitatory and inhibitory neuronal processing and atypical visual processing in ASD

Abstract

POU3F3, also referred to as Brain-1, is a well-known transcription factor involved in the development of the central nervous system, but it has not previously been associated with a neurodevelopmental disorder. Here, we report the identification of 19 individuals with heterozygous POU3F3 disruptions, most of which are de novo variants. All individuals had developmental delays and/or intellectual disability and impairments in speech and language skills. Thirteen individuals had characteristic low-set, prominent, and/or cupped ears. Brain abnormalities were observed in seven of eleven MRI reports. POU3F3 is an intronless gene, insensitive to nonsense-mediated decay, and 13 individuals carried protein-truncating variants. All truncating variants that we tested in cellular models led to aberrant subcellular localization of the encoded protein. Luciferase assays demonstrated negative effects of these alleles on transcriptional activation of a reporter with a FOXP2-derived binding motif. In addition to the loss-of-function variants, five individuals had missense variants that clustered at specific positions within the functional domains, and one small in-frame deletion was identified. Two missense variants showed reduced transactivation capacity in our assays, whereas one variant displayed gain-of-function effects, suggesting a distinct pathophysiological mechanism. In bioluminescence resonance energy transfer (BRET) interaction assays, all the truncated POU3F3 versions that we tested had significantly impaired dimerization capacities, whereas all missense variants showed unaffected dimerization with wild-type POU3F3. Taken together, our identification and functional cell-based analyses of pathogenic variants in POU3F3, coupled with a clinical characterization, implicate disruptions of this gene in a characteristic neurodevelopmental disorder.

Abstract

The anterior cingulate cortex (ACC) and the dorsolateral prefrontal cortex (DLPFC) are involved in conflict detection and
conflict resolution, respectively. Here, we investigate how lifelong bilingualism induces neuroplasticity to these structures by
employing a novel analysis of behavioural performance. We correlated grey matter volume (GMV) in seniors reported by
Abutalebi et al. (2015) with behavioral Flanker task performance fitted using the diffusion model (Ratcliff, 1978). As
predicted, we observed significant correlations between GMV in the DLPFC and Flanker performance. However, for
monolinguals the non-decision time parameter was significantly correlated with GMV in the left DLPFC, whereas for
bilinguals the correlation was significant in the right DLPFC. We also found a significant correlation between age and GMV
in left DLPFC and the non-decision time parameter for the conflict effect for monolinguals only.
We submit that this is due to cumulative demands on cognitive control over a lifetime of bilingual language processing

Abstract

In language comprehension, a variety of contextual cues act in unison to render upcoming words more or less predictable. As a sentence unfolds, we use prior context (sentential constraints) to predict what the next words might be. Additionally, in a conversation, we can predict upcoming sounds through observing the mouth movements of a speaker (visual constraints). In electrophysiological studies, effects of visual constraints have typically been observed early in language processing, while effects of sentential constraints have typically been observed later. We hypothesized that the visual and the sentential constraints might feed into the same predictive process such that effects of sentential constraints might also be detectable early in language processing through modulations of the early effects of visual salience. We presented participants with audiovisual speech while recording their brain activity with magnetoencephalography. Participants saw videos of a person saying sentences where the last word was either sententially constrained or not, and began with a salient or non-salient mouth movement. We found that sentential constraints indeed exerted an early (N1) influence on language processing. Sentential modulations of the N1 visual predictability effect were visible in brain areas associated with semantic processing, and were differently expressed in the two hemispheres. In the left hemisphere, visual and sentential constraints jointly suppressed the auditory evoked field, while the right hemisphere was sensitive to visual constraints only in the absence of strong sentential constraints. These results suggest that sentential and visual constraints can jointly influence even very early stages of audiovisual speech comprehension.

Abstract

Humans have a strong proclivity for structuring and patterning stimuli: Whether in space or time, we tend to mentally order stimuli in our environment and organize them into units with specific types of relationships. A crucial prerequisite for such organization is the cognitive ability to discern and process regularities among multiple stimuli. To investigate the evolutionary roots of this cognitive capacity, we tested chimpanzees—which, along with bonobos, are our closest living relatives—for simple, variable distance dependency processing in visual patterns. We trained chimpanzees to identify pairs of shapes either linked by an arbitrary learned association (arbitrary associative dependency) or a shared feature (same shape, feature-based dependency), and to recognize strings where items related to either of these ways occupied the first (leftmost) and the last (rightmost) item of the stimulus. We then probed the degree to which subjects generalized this pattern to new colors, shapes, and numbers of interspersed items. We found that chimpanzees can learn and generalize both types of dependency rules, indicating that the ability to encode both feature-based and arbitrary associative regularities over variable distances in the visual domain is not a human prerogative. Our results strongly suggest that these core components of human structural processing were already present in our last common ancestor with chimpanzees.

Abstract

Flexibly adapting social behavior to social and environmental challenges helps to alleviate glucocorticoid (GC) levels, which may have positive fitness implications for an individual. For primates, the predominant social behavior is grooming. Giving grooming to others is particularly efficient in terms of GC mitigation. However, grooming is confined by certain limitations such as time constraints or restricted access to other group members. For instance, dominance hierarchies may impact grooming partner availability in primate societies. Consequently specific grooming patterns emerge. In despotic species focusing grooming activity on preferred social partners significantly ameliorates GC levels in females of all ranks. In this study we investigated grooming patterns and GC management in Barbary macaques, a comparably relaxed species. We monitored changes in grooming behavior and cortisol (C) for females of different ranks. Our results show that the C‐amelioration associated with different grooming patterns had a gradual connection with dominance hierarchy: while higher‐ranking individuals showed lowest urinary C measures when they focused their grooming on selected partners within their social network, lower‐ranking individuals expressed lowest C levels when dispersing their grooming activity evenly across their social partners. We argue that the relatively relaxed social style of Barbary macaque societies allows individuals to flexibly adapt grooming patterns, which is associated with rank‐specific GC management. Am. J. Primatol. 77:688–700, 2015

Abstract

Aims/hypothesis Several forkhead box (FOX) transcription factor family members have important roles in controlling pancreatic cell fates and maintaining beta cell mass and function, including FOXA1, FOXA2 and FOXM1. In this study we have examined the importance of FOXP1, FOXP2 and FOXP4 of the FOXP subfamily in islet cell development and function. Methods Mice harbouring floxed alleles for Foxp1, Foxp2 and Foxp4 were crossed with pan-endocrine Pax6-Cre transgenic mice to generate single and compound Foxp mutant mice. Mice were monitored for changes in glucose tolerance by IPGTT, serum insulin and glucagon levels by radioimmunoassay, and endocrine cell development and proliferation by immunohistochemistry. Gene expression and glucose-stimulated hormone secretion experiments were performed with isolated islets. Results Only the triple-compound Foxp1/2/4 conditional knockout (cKO) mutant had an overt islet phenotype, manifested physiologically by hypoglycaemia and hypoglucagonaemia. This resulted from the reduction in glucagon-secreting alpha cell mass and function. The proliferation of alpha cells was profoundly reduced in Foxp1/2/4 cKO islets through the effects on mediators of replication (i.e. decreased Ccna2, Ccnb1 and Ccnd2 activators, and increased Cdkn1a inhibitor). Adult islet Foxp1/2/4 cKO beta cells secrete insulin normally while the remaining alpha cells have impaired glucagon secretion. Conclusions/interpretation Collectively, these findings reveal an important role for the FOXP1, 2, and 4 proteins in governing postnatal alpha cell expansion and function.

Abstract

E-Prime® is the leading software suite by Psychology Software Tools for designing and running Psychology lab experiments. The E-Primer is the perfect accompanying guide: It provides all the necessary knowledge to make E-Prime accessible to everyone. You can learn the tools of Psychological science by following the E-Primer through a series of entertaining, step-by-step recipes that recreate classic experiments. The updated E-Primer expands its proven combination of simple explanations, interesting tutorials and fun exercises, and makes even the novice student quickly confident to create their dream experiment.

Abstract

Odors are often difficult to identify and name, which leaves them vulnerable to the influence of language. The present study tests the boundaries of the effect of language on odor cognition by examining the effect of grammatical gender. We presented participants with male and female fragrances paired with descriptions of masculine or feminine grammatical gender. In Experiment 1 we found that memory for fragrances was enhanced when the grammatical gender of a fragrance description matched the gender of the fragrance. In Experiment 2 we found memory for fragrances was affected by both grammatical gender and gender associations in fragrance descriptions – recognition memory for odors was higher when the gender was incongruent. In sum, we demonstrated that even subtle aspects of language can affect odor cognition.

Abstract

Metaphor allows us to think and talk about one thing in terms of another, ratcheting up our cognitive and expressive capacity. It gives us concrete terms for abstract phenomena, for example, ideas become things we can grasp or let go of. Perceptual experience—characterised as physical and relatively concrete—should be an ideal source domain in metaphor, and a less likely target. But is this the case across diverse languages? And are some sensory modalities perhaps more concrete than others? This volume presents critical new data on perception metaphors from over 40 languages, including many which are under-studied. Aside from the wealth of data from diverse languages—modern and historical; spoken and signed—a variety of methods (e.g., natural language corpora, experimental) and theoretical approaches are brought together. This collection highlights how perception metaphor can offer both a bedrock of common experience and a source of continuing innovation in human communication

Abstract

The response exclusion account (REA), advanced by Mahon and colleagues, localises the distractor frequency effect and the semantic interference effect in picture naming at the level of the response output buffer. We derive four predictions from the REA: (1) the size of the distractor frequency effect should be identical to the frequency effect obtained when distractor words are read aloud, (2) the distractor frequency effect should not change in size when stimulus-onset asynchrony (SOA) is manipulated, (3) the interference effect induced by a distractor word (as measured from a nonword control distractor) should increase in size with increasing SOA, and (4) the word frequency effect and the semantic interference effect should be additive. The results of the picture-naming task in Experiment 1 and the word-reading task in Experiment 2 refute all four predictions. We discuss a tentative account of the findings obtained within a traditional selection-by-competition model in which both context effects are localised at the level of lexical selection.

Abstract

Neuronal nicotinic acetylcholine receptor (nAChR) genes (CHRNA5/CHRNA3/CHRNB4) have been reproducibly associated with nicotine dependence, smoking behaviors, and lung cancer risk. Of the few reports that have focused on early smoking behaviors, association results have been mixed. This meta-analysis examines early smoking phenotypes and SNPs in the gene cluster to determine: (1) whether the most robust association signal in this region (rs16969968) for other smoking behaviors is also associated with early behaviors, and/or (2) if additional statistically independent signals are important in early smoking. We focused on two phenotypes: age of tobacco initiation (AOI) and age of first regular tobacco use (AOS). This study included 56,034 subjects (41 groups) spanning nine countries and evaluated five SNPs including rs1948, rs16969968, rs578776, rs588765, and rs684513. Each dataset was analyzed using a centrally generated script. Meta-analyses were conducted from summary statistics. AOS yielded significant associations with SNPs rs578776 (beta = 0.02, P = 0.004), rs1948 (beta = 0.023, P = 0.018), and rs684513 (beta = 0.032, P = 0.017), indicating protective effects. There were no significant associations for the AOI phenotype. Importantly, rs16969968, the most replicated signal in this region for nicotine dependence, cigarettes per day, and cotinine levels, was not associated with AOI (P = 0.59) or AOS (P = 0.92). These results provide important insight into the complexity of smoking behavior phenotypes, and suggest that association signals in the CHRNA5/A3/B4 gene cluster affecting early smoking behaviors may be different from those affecting the mature nicotine dependence phenotype

Abstract

The principle of common coding suggests that a joint representation is formed when actions are repeatedly paired with a specific perceptual event. Musicians are occupationally specialized with regard to the coupling between actions and their auditory effects. In the present study, we employed a novel paradigm to demonstrate automatic action–effect associations in pianists. Pianists and nonmusicians pressed keys according to aurally presented number sequences. Numbers were presented at pitches that were neutral, congruent, or incongruent with respect to pitches that would normally be produced by such actions. Response time differences were seen between congruent and incongruent sequences in pianists alone. A second experiment was conducted to determine whether these effects could be attributed to the existence of previously documented spatial/pitch compatibility effects. In a “stretched” version of the task, the pitch distance over which the numbers were presented was enlarged to a range that could not be produced by the hand span used in Experiment 1. The finding of a larger response time difference between congruent and incongruent trials in the original, standard, version compared with the stretched version, in pianists, but not in nonmusicians, indicates that the effects obtained are, at least partially, attributable to learned action effects.

Abstract

Presenting a comprehensive, state-of-the-art overview of theoretical and descriptive research in the field, The Handbook of Conversation Analysis brings together contributions by leading international experts to provide an invaluable information resource and reference for scholars of social interaction across the areas of conversation analysis, discourse analysis, linguistic anthropology, interpersonal communication, discursive psychology and sociolinguistics. Ideal as an introduction to the field for upper level undergraduates and as an in-depth review of the latest developments for graduate level students and established scholars Five sections outline the history and theory, methods, fundamental concepts, and core contexts in the study of conversation, as well as topics central to conversation analysis Written by international conversation analysis experts, the book covers a wide range of topics and disciplines, from reviewing underlying structures of conversation, to describing conversation analysis' relationship to anthropology, communication, linguistics, psychology, and sociology

Abstract

Bilingual children are often exposed to non-native speech through their parents. Yet, little is known about the relation between bilingual preschoolers’ speech production and their speech input. The present study investigated the production of voice onset time (VOT) by Dutch-German bilingual preschoolers and their sequential bilingual mothers. The findings reveal an association between maternal VOT and bilingual children’s VOT in the heritage language German as well as in the majority language Dutch. By contrast, no input-production association was observed in the VOT production of monolingual German-speaking children and monolingual Dutch-speaking children. The results of this study provide the first empirical evidence that non-native and attrited maternal speech contributes to the often-observed linguistic differences between bilingual children and their monolingual peers.

Abstract

Human referential communication is often thought as coding-decoding a set of symbols, neglecting that establishing shared meanings requires a computational mechanism powerful enough to mutually negotiate them. Sharing the meaning of a novel symbol might rely on similar conceptual inferences across communicators or on statistical similarities in their sensorimotor behaviors. Using magnetoencephalography, we assess spectral, temporal, and spatial characteristics of neural activity evoked when people generate and understand novel shared symbols during live communicative interactions. Solving those communicative problems induced comparable changes in the spectral profile of neural activity of both communicators and addressees. This shared neuronal up-regulation was spatially localized to the right temporal lobe and the ventromedial prefrontal cortex and emerged already before the occurrence of a specific communicative problem. Communicative innovation relies on neuronal computations that are shared across generating and understanding novel shared symbols, operating over temporal scales independent from transient sensorimotor behavior.

Abstract

Magnetoencephalography (MEG) is measured above the head, which makes it sensitive to variations of the head position with respect to the sensors. Head movements blur the topography of the neuronal sources of the MEG signal, increase localization errors, and reduce statistical sensitivity. Here we describe two novel and readily applicable methods that compensate for the detrimental effects of head motion on the statistical sensitivity of MEG experiments. First, we introduce an online procedure that continuously monitors head position. Second, we describe an offline analysis method that takes into account the head position time-series. We quantify the performance of these methods in the context of three different experimental settings, involving somatosensory, visual and auditory stimuli, assessing both individual and group-level statistics. The online head localization procedure allowed for optimal repositioning of the subjects over multiple sessions, resulting in a 28% reduction of the variance in dipole position and an improvement of up to 15% in statistical sensitivity. Offline incorporation of the head position time-series into the general linear model resulted in improvements of group-level statistical sensitivity between 15% and 29%. These tools can substantially reduce the influence of head movement within and between sessions, increasing the sensitivity of many cognitive neuroscience experiments.

Abstract

In sign languages, where space is often used to talk about space, expressions of spatial relations (e.g., ON, IN, UNDER, BEHIND) may rely on analogue mappings of real space onto signing space. In contrast, spoken languages express space in mostly categorical ways (e.g. adpositions). This raises interesting questions about the role of language modality in the acquisition of expressions of spatial relations. However, whether and to what extent modality influences the acquisition of spatial language is controversial – mostly due to the lack of direct comparisons of Deaf children to Deaf adults and to age-matched hearing children in similar tasks. Furthermore, the previous studies have taken English as the only model for spoken language development of spatial relations.
Therefore, we present a balanced study in which spatial expressions by deaf and hearing children in two different age-matched groups (preschool children and school-age children) are systematically compared, as well as compared to the spatial expressions of adults. All participants performed the same tasks, describing angular (LEFT, RIGHT, FRONT, BEHIND) and non-angular spatial configurations (IN, ON, UNDER) of different objects (e.g. apple in box; car behind box).
The analysis of the descriptions with non-angular spatial relations does not show an effect of modality on the development of
locative expressions in TİD and Turkish. However, preliminary results of the analysis of expressions of angular spatial relations suggest that signers provide angular information in their spatial descriptions
more frequently than Turkish speakers in all three age groups, and thus showing a potentially different developmental pattern in this domain. Implications of the findings with regard to the development of relations in spatial language and cognition will be discussed.