Publications

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  • Corps, R. E., Gambi, C., & Pickering, M. J. (2020). How do listeners time response articulation when answering questions? The role of speech rate. Journal of Experimental Psychology: Learning, Memory, and Cognition, 46(4), 781-802. doi:10.1037/xlm0000759.

    Abstract

    During conversation, interlocutors often produce their utterances with little overlap or gap between their turns. But what mechanism underlies this striking ability to time articulation appropriately? In 2 verbal yes/no question-answering experiments, we investigated whether listeners use the speech rate of questions to time articulation of their answers. In Experiment 1, we orthogonally manipulated the speech rate of the context (e.g., Do you have a . . .) and final word (e.g., dog?) of questions using time-compression, so that each component was spoken at the natural rate or twice as a fast. Listeners responded earlier when the context was speeded rather than natural, suggesting they used the speaker’s context rate to time answer articulation. Additionally, listeners responded earlier when the speaker’s final syllable was speeded than natural, regardless of context rate, suggesting they adjusted the timing of articulation after listening to a single syllable produced at a different rate. We replicated this final word effect in Experiment 2, which also showed that our speech rate manipulation did not influence the timing of response preparation. Together, these findings suggest listeners use speech rate information to time articulation when answering questions
  • Corps, R. E., & Rabagliati, H. (2020). How top-down processing enhances comprehension of noise-vocoded speech: Predictions about meaning are more important than predictions about form. Journal of Memory and Language, 113: 104114. doi:10.1016/j.jml.2020.104114.

    Abstract

    Listeners quickly learn to understand speech that has been distorted, and this process is enhanced when comprehension is constrained by higher-level knowledge. In three experiments, we investigated whether this knowledge enhances comprehension of distorted speech because it allows listeners to predict (1) the meaning of the distorted utterance, or (2) the lower-level wordforms. Participants listened to question-answer sequences, in which questions were clearly-spoken but answers were noise-vocoded. Comprehension (Experiment 1) and learning (Experiment 2) were enhanced when listeners could use the question to predict the semantics of the distorted answer, but were not enhanced by predictions of answer form. Form predictions enhanced comprehension only when questions and answers were significantly separated by time and intervening linguistic material (Experiment 3). Together, these results suggest that high-level semantic predictions enhance comprehension and learning, with form predictions playing only a minimal role.
  • Cousijn, H., Eissing, M., Fernández, G., Fisher, S. E., Franke, B., Zwers, M., Harrison, P. J., & Arias-Vasquez, A. (2014). No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure. Schizophrenia Research, 159, 329-332. doi:10.1016/j.schres.2014.08.007.

    Abstract

    Single nucleotide polymorphisms (SNPs) within the MIR137, TCF4, and ZNF804A genes show genome-wide association to schizophrenia. However, the biological basis for the associations is unknown. Here, we tested the effects of these genes on brain structure in 1300 healthy adults. Using volumetry and voxel-based morphometry, neither gene-wide effects—including the combined effect of the genes—nor single SNP effects—including specific psychosis risk SNPs—were found on total brain volume, grey matter, white matter, or hippocampal volume. These results suggest that the associations between these risk genes and schizophrenia are unlikely to be mediated via effects on macroscopic brain structure.
  • Cozijn, R., Noordman, L. G., & Vonk, W. (2011). Propositional integration and world-knowledge inference: Processes in understanding because sentences. Discourse Processes, 48, 475-500. doi:10.1080/0163853X.2011.594421.

    Abstract

    The issue addressed in this study is whether propositional integration and world-knowledge inference can be distinguished as separate processes during the comprehension of Dutch omdat (because) sentences. “Propositional integration” refers to the process by which the reader establishes the type of relation between two clauses or sentences. “World-knowledge inference” refers to the process of deriving the general causal relation and checking it against the reader's world knowledge. An eye-tracking experiment showed that the presence of the conjunction speeds up the processing of the words immediately following the conjunction, and slows down the processing of the sentence final words in comparison to the absence of the conjunction. A second, subject-paced reading experiment replicated the reading time findings, and the results of a verification task confirmed that the effect at the end of the sentence was due to inferential processing. The findings evidence integrative processing and inferential processing, respectively.
  • Cozijn, R., Commandeur, E., Vonk, W., & Noordman, L. G. (2011). The time course of the use of implicit causality information in the processing of pronouns: A visual world paradigm study. Journal of Memory and Language, 64, 381-403. doi:10.1016/j.jml.2011.01.001.

    Abstract

    Several theoretical accounts have been proposed with respect to the issue how quickly the implicit causality verb bias affects the understanding of sentences such as “John beat Pete at the tennis match, because he had played very well”. They can be considered as instances of two viewpoints: the focusing and the integration account. The focusing account claims that the bias should be manifest soon after the verb has been processed, whereas the integration account claims that the interpretation is deferred until disambiguating information is encountered. Up to now, this issue has remained unresolved because materials or methods have failed to address it conclusively. We conducted two experiments that exploited the visual world paradigm and ambiguous pronouns in subordinate because clauses. The first experiment presented implicit causality sentences with the task to resolve the ambiguous pronoun. To exclude strategic processing, in the second experiment, the task was to answer simple comprehension questions and only a minority of the sentences contained implicit causality verbs. In both experiments, the implicit causality of the verb had an effect before the disambiguating information was available. This result supported the focusing account.
  • Creemers, A., Goodwin Davies, A., Wilder, R. J., Tamminga, M., & Embick, D. (2020). Opacity, transparency, and morphological priming: A study of prefixed verbs in Dutch. Journal of Memory and Language, 110: 104055. doi:10.1016/j.jml.2019.104055.

    Abstract

    A basic question for the study of the mental lexicon is whether there are morphological representations and processes that are independent of phonology and semantics. According to a prominent tradition, morphological relatedness requires semantic transparency: semantically transparent words are related in meaning to their stems, while semantically opaque words are not. This study examines the question of morphological relatedness using intra-modal auditory priming by Dutch prefixed verbs. The key conditions involve semantically transparent prefixed primes (e.g., aanbieden ‘offer’, with the stem bieden, also ‘offer’) and opaque primes (e.g., verbieden ‘forbid’). Results show robust facilitation for both transparent and opaque pairs; phonological (Experiment 1) and semantic (Experiment 2) controls rule out the possibility that these other types of relatedness are responsible for the observed priming effects. The finding of facilitation with opaque primes suggests that morphological processing is independent of semantic and phonological representations. Accordingly, the results are incompatible with theories that make semantic overlap a necessary condition for relatedness, and favor theories in which words may be related in ways that do not require shared meaning. The general discussion considers several specific proposals along these lines, and compares and contrasts questions about morphological relatedness of the type found here with the different but related question of whether there is morphological decomposition of complex forms or not.
  • Cristia, A., McGuire, G. L., Seidl, A., & Francis, A. L. (2011). Effects of the distribution of acoustic cues on infants' perception of sibilants. Journal of Phonetics, 39, 388-402. doi:10.1016/j.wocn.2011.02.004.

    Abstract

    A current theoretical view proposes that infants converge on the speech categories of their native language by attending to frequency distributions that occur in the acoustic input. To date, the only empirical support for this statistical learning hypothesis comes from studies where a single, salient dimension was manipulated. Additional evidence is sought here, by introducing a less salient pair of categories supported by multiple cues. We exposed English-learning infants to a multi-cue bidimensional grid ranging between retroflex and alveolopalatal sibilants in prevocalic position. This contrast is substantially more difficult according to previous cross-linguistic and perceptual research, and its perception is driven by cues in both the consonantal and the following vowel portions. Infants heard one of two distributions (flat, or with two peaks), and were tested with sounds varying along only one dimension. Infants' responses differed depending on the familiarization distribution, and their performance was equally good for the vocalic and the frication dimension, lending some support to the statistical hypothesis even in this harder learning situation. However, learning was restricted to the retroflex category, and a control experiment showed that lack of learning for the alveolopalatal category was not due to the presence of a competing category. Thus, these results contribute fundamental evidence on the extent and limitations of the statistical hypothesis as an explanation for infants' perceptual tuning.
  • Cristia, A. (2011). Fine-grained variation in caregivers' speech predicts their infants' discrimination. Journal of the Acoustical Society of America, 129, 3271-3280. doi:10.1121/1.3562562.

    Abstract

    Within the debate on the mechanisms underlying infants’ perceptual acquisition, one hypothesis proposes that infants’ perception is directly affected by the acoustic implementation of sound categories in the speech they hear. In consonance with this view, the present study shows that individual variation in fine-grained, subphonemic aspects of the acoustic realization of /s/ in caregivers’ speech predicts infants’ discrimination of this sound from the highly similar /∫/, suggesting that learning based on acoustic cue distributions may indeed drive natural phonological acquisition.
  • Cristia, A., Seidl, A., & Gerken, L. (2011). Learning classes of sounds in infancy. University of Pennsylvania Working Papers in Linguistics, 17, 9.

    Abstract

    Adults' phonotactic learning is affected by perceptual biases. One such bias concerns learning of constraints affecting groups of sounds: all else being equal, learning constraints affecting a natural class (a set of sounds sharing some phonetic characteristic) is easier than learning a constraint affecting an arbitrary set of sounds. This perceptual bias could be a given, for example, the result of innately guided learning; alternatively, it could be due to human learners’ experience with sounds. Using artificial grammars, we investigated whether such a bias arises in development, or whether it is present as soon as infants can learn phonotactics. Seven-month-old English-learning infants fail to generalize a phonotactic pattern involving fricatives and nasals, which does not form a coherent phonetic group, but succeed with the natural class of oral and nasal stops. In this paper, we report an experiment that explored whether those results also follow in a cohort of 4-month-olds. Unlike the older infants, 4-month-olds were able to generalize both groups, suggesting that the perceptual bias that makes phonotactic constraints on natural classes easier to learn is likely the effect of experience.
  • Cristia, A., Minagawa-Kawai, Y., Egorova, N., Gervain, J., Filippin, L., Cabrol, D., & Dupoux, E. (2014). Neural correlates of infant accent discrimination: An fNIRS study. Developmental Science, 17(4), 628-635. doi:10.1111/desc.12160.

    Abstract

    The present study investigated the neural correlates of infant discrimination of very similar linguistic varieties (Quebecois and Parisian French) using functional Near InfraRed Spectroscopy. In line with previous behavioral and electrophysiological data, there was no evidence that 3-month-olds discriminated the two regional accents, whereas 5-month-olds did, with the locus of discrimination in left anterior perisylvian regions. These neuroimaging results suggest that a developing language network relying crucially on left perisylvian cortices sustains infants' discrimination of similar linguistic varieties within this early period of infancy.

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  • Cristia, A., Seidl, A., & Francis, A. L. (2011). Phonological features in infancy. In G. N. Clements, & R. Ridouane (Eds.), Where do phonological contrasts come from? Cognitive, physical and developmental bases of phonological features (pp. 303-326). Amsterdam: Benjamins.

    Abstract

    Features serve two main functions in the phonology of languages: they encode the distinction between pairs of contrastive phonemes (distinctive function); and they delimit sets of sounds that participate in phonological processes and patterns (classificatory function). We summarize evidence from a variety of experimental paradigms bearing on the functional relevance of phonological features. This research shows that while young infants may use abstract phonological features to learn sound patterns, this ability becomes more constrained with development and experience. Furthermore, given the lack of overlap between the ability to learn a pair of words differing in a single feature and the ability to learn sound patterns based on features, we argue for the separation of the distinctive and the classificatory function.
  • Cristia, A., & Seidl, A. (2011). Sensitivity to prosody at 6 months predicts vocabulary at 24 months. In N. Danis, K. Mesh, & H. Sung (Eds.), BUCLD 35: Proceedings of the 35th annual Boston University Conference on Language Development (pp. 145-156). Somerville, Mass: Cascadilla Press.
  • Cristia, A., Seidl, A., Junge, C., Soderstrom, M., & Hagoort, P. (2014). Predicting individual variation in language from infant speech perception measures. Child development, 85(4), 1330-1345. doi:10.1111/cdev.12193.

    Abstract

    There are increasing reports that individual variation in behavioral and neurophysiological measures of infant speech processing predicts later language outcomes, and specifically concurrent or subsequent vocabulary size. If such findings are held up under scrutiny, they could both illuminate theoretical models of language development and contribute to the prediction of communicative disorders. A qualitative, systematic review of this emergent literature illustrated the variety of approaches that have been used and highlighted some conceptual problems regarding the measurements. A quantitative analysis of the same data established that the bivariate relation was significant, with correlations of similar strength to those found for well-established nonlinguistic predictors of language. Further exploration of infant speech perception predictors, particularly from a methodological perspective, is recommended.
  • Cristia, A., & Seidl, A. (2014). The hyperarticulation hypothesis of infant-directed speech. Journal of Child Language, 41(4), 913-934. doi:10.1017/S0305000912000669.

    Abstract

    Typically, the point vowels [i,ɑ,u] are acoustically more peripheral in infant-directed speech (IDS) compared to adult-directed speech (ADS). If caregivers seek to highlight lexically relevant contrasts in IDS, then two sounds that are contrastive should become more distinct, whereas two sounds that are surface realizations of the same underlying sound category should not. To test this prediction, vowels that are phonemically contrastive ([i-ɪ] and [eɪ-ε]), vowels that map onto the same underlying category ([æ- ] and [ε- ]), and the point vowels [i,ɑ,u] were elicited in IDS and ADS by American English mothers of two age groups of infants (four- and eleven-month-olds). As in other work, point vowels were produced in more peripheral positions in IDS compared to ADS. However, there was little evidence of hyperarticulation per se (e.g. [i-ɪ] was hypoarticulated). We suggest that across-the-board lexically based hyperarticulation is not a necessary feature of IDS.

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    CORRIGENDUM
  • Croijmans, I., Hendrickx, I., Lefever, E., Majid, A., & Van den Bosch, A. (2020). Uncovering the language of wine experts. Natural Language Engineering, 26(5), 511-530. doi:10.1017/S1351324919000500.

    Abstract

    Talking about odors and flavors is difficult for most people, yet experts appear to be able to convey critical information about wines in their reviews. This seems to be a contradiction, and wine expert descriptions are frequently received with criticism. Here, we propose a method for probing the language of wine reviews, and thus offer a means to enhance current vocabularies, and as a by-product question the general assumption that wine reviews are gibberish. By means of two different quantitative analyses—support vector machines for classification and Termhood analysis—on a corpus of online wine reviews, we tested whether wine reviews are written in a consistent manner, and thus may be considered informative; and whether reviews feature domain-specific language. First, a classification paradigm was trained on wine reviews from one set of authors for which the color, grape variety, and origin of a wine were known, and subsequently tested on data from a new author. This analysis revealed that, regardless of individual differences in vocabulary preferences, color and grape variety were predicted with high accuracy. Second, using Termhood as a measure of how words are used in wine reviews in a domain-specific manner compared to other genres in English, a list of 146 wine-specific terms was uncovered. These words were compared to existing lists of wine vocabulary that are currently used to train experts. Some overlap was observed, but there were also gaps revealed in the extant lists, suggesting these lists could be improved by our automatic analysis.
  • Cronin, K. A., Van Leeuwen, E. J. C., Mulenga, I. C., & Bodamer, M. D. (2011). Behavioral response of a chimpanzee mother toward her dead infant. American Journal of Primatology, 73(5), 415-421. doi:10.1002/ajp.20927.

    Abstract

    The mother-offspring bond is one of the strongest and most essential social bonds. Following is a detailed behavioral report of a female chimpanzee two days after her 16-month-old infant died, on the first day that the mother is observed to create distance between her and the corpse. A series of repeated approaches and retreats to and from the body are documented, along with detailed accounts of behaviors directed toward the dead infant by the mother and other group members. The behavior of the mother toward her dead infant not only highlights the maternal contribution to the mother-infant relationship but also elucidates the opportunities chimpanzees have to learn about the sensory cues associated with death, and the implications of death for the social environment.
  • Cronin, K. A., Pieper, B., Van Leeuwen, E. J. C., Mundry, R., & Haun, D. B. M. (2014). Problem solving in the presence of others: How rank and relationship quality impact resource acquisition in chimpanzees (Pan troglodytes). PLoS One, 9(4): e93204. doi:10.1371/journal.pone.0093204.

    Abstract

    In the wild, chimpanzees (Pan troglodytes) are often faced with clumped food resources that they may know how to access but abstain from doing so due to social pressures. To better understand how social settings influence resource acquisition, we tested fifteen semi-wild chimpanzees from two social groups alone and in the presence of others. We investigated how resource acquisition was affected by relative social dominance, whether collaborative problem solving or (active or passive) sharing occurred amongst any of the dyads, and whether these outcomes were related to relationship quality as determined from six months of observational data. Results indicated that chimpanzees, regardless of rank, obtained fewer rewards when tested in the presence of others compared to when they were tested alone. Chimpanzees demonstrated behavioral inhibition; chimpanzees who showed proficient skill when alone often abstained from solving the task when in the presence of others. Finally, individuals with close social relationships spent more time together in the problem solving space, but collaboration and sharing were infrequent and sessions in which collaboration or sharing did occur contained more instances of aggression. Group living provides benefits and imposes costs, and these findings highlight that one cost of group living may be diminishing productive individual behaviors.
  • Cronin, K. A., Van Leeuwen, E. J. C., Vreeman, V., & Haun, D. B. M. (2014). Population-level variability in the social climates of four chimpanzee societies. Evolution and Human Behavior, 35(5), 389-396. doi:10.1016/j.evolhumbehav.2014.05.004.

    Abstract

    Recent debates have questioned the extent to which culturally-transmitted norms drive behavioral variation in resource sharing across human populations. We shed new light on this discussion by examining the group-level variation in the social dynamics and resource sharing of chimpanzees, a species that is highly social and forms long-term community associations but differs from humans in the extent to which cultural norms are adopted and enforced. We rely on theory developed in primate socioecology to guide our investigation in four neighboring chimpanzee groups at a sanctuary in Zambia. We used a combination of experimental and observational approaches to assess the distribution of resource holding potential in each group. In the first assessment, we measured the proportion of the population that gathered in a resource-rich zone, in the second we assessed naturally occurring social spacing via social network analysis, and in the third we assessed the degree to which benefits were equally distributed within the group. We report significant, stable group-level variation across these multiple measures, indicating that group-level variation in resource sharing and social tolerance is not necessarily reliant upon human-like cultural norms.
  • Cross, Z. R., Santamaria, A., Corcoran, A. W., Chatburn, A., Alday, P. M., Coussens, S., & Kohler, M. J. (2020). Individual alpha frequency modulates sleep-related emotional memory consolidation. Neuropsychologia, 148: 107660. doi:10.1016/j.neuropsychologia.2020.107660.

    Abstract

    Alpha-band oscillatory activity is involved in modulating memory and attention. However, few studies have investigated individual differences in oscillatory activity during the encoding of emotional memory, particularly in sleep paradigms where sleep is thought to play an active role in memory consolidation. The current study aimed to address the question of whether individual alpha frequency (IAF) modulates the consolidation of declarative memory across periods of sleep and wake. 22 participants aged 18 – 41 years (mean age = 25.77) viewed 120 emotionally valenced images (positive, negative, neutral) and completed a baseline memory task before a 2hr afternoon sleep opportunity and an equivalent period of wake. Following the sleep and wake conditions, participants were required to distinguish between 120 learned (target) images and 120 new (distractor) images. This method allowed us to delineate the role of different oscillatory components of sleep and wake states in the emotional modulation of memory. Linear mixed-effects models revealed interactions between IAF, rapid eye movement sleep theta power, and slow-wave sleep slow oscillatory density on memory outcomes. These results highlight the importance of individual factors in the EEG in modulating oscillatory-related memory consolidation and subsequent behavioural outcomes and test predictions proposed by models of sleep-based memory consolidation.

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  • Cutler, A. (2002). Phonological processing: Comments on Pierrehumbert, Moates et al., Kubozono, Peperkamp & Dupoux, and Bradlow. In C. Gussenhoven, & N. Warner (Eds.), Papers in Laboratory Phonology VII (pp. 275-296). Berlin: Mouton de Gruyter.
  • Cutler, A., & Otake, T. (2002). Rhythmic categories in spoken-word recognition. Journal of Memory and Language, 46(2), 296-322. doi:10.1006/jmla.2001.2814.

    Abstract

    Rhythmic categories such as morae in Japanese or stress units in English play a role in the perception of spoken
    language. We examined this role in Japanese, since recent evidence suggests that morae may intervene as
    structural units in word recognition. First, we found that traditional puns more often substituted part of a mora
    than a whole mora. Second, when listeners reconstructed distorted words, e.g. panorama from panozema, responses
    were faster and more accurate when only a phoneme was distorted (panozama, panorema) than when a
    whole CV mora was distorted (panozema). Third, lexical decisions on the same nonwords were better predicted
    by duration and number of phonemes from nonword uniqueness point to word end than by number of morae. Our
    results indicate no role for morae in early spoken-word processing; we propose that rhythmic categories constrain
    not initial lexical activation but subsequent processes of speech segmentation and selection among word candidates.
  • Cutler, A. (2004). Segmentation of spoken language by normal adult listeners. In R. Kent (Ed.), MIT encyclopedia of communication sciences and disorders (pp. 392-395). Cambridge, MA: MIT Press.
  • Cutler, A., Weber, A., Smits, R., & Cooper, N. (2004). Patterns of English phoneme confusions by native and non-native listeners. Journal of the Acoustical Society of America, 116(6), 3668-3678. doi:10.1121/1.1810292.

    Abstract

    Native American English and non-native(Dutch)listeners identified either the consonant or the vowel in all possible American English CV and VC syllables. The syllables were embedded in multispeaker babble at three signal-to-noise ratios(0, 8, and 16 dB). The phoneme identification
    performance of the non-native listeners was less accurate than that of the native listeners. All listeners were adversely affected by noise. With these isolated syllables, initial segments were harder to identify than final segments. Crucially, the effects of language background and noise did not interact; the performance asymmetry between the native and non-native groups was not significantly different across signal-to-noise ratios. It is concluded that the frequently reported disproportionate difficulty of non-native listening under disadvantageous conditions is not due to a disproportionate increase in phoneme misidentifications.
  • Cutler, A. (2004). On spoken-word recognition in a second language. Newsletter, American Association of Teachers of Slavic and East European Languages, 47, 15-15.
  • Cutler, A., & Norris, D. (2002). The role of strong syllables in segmentation for lexical access. In G. T. Altmann (Ed.), Psycholinguistics: Critical concepts in psychology (pp. 157-177). London: Routledge.
  • Cutler, A., Mehler, J., Norris, D., & Segui, J. (2002). The syllable's differing role in the segmentation of French and English. In G. T. Altmann (Ed.), Psycholinguistics: Critical concepts in psychology (pp. 115-135). London: Routledge.

    Abstract

    Speech segmentation procedures may differ in speakers of different languages. Earlier work based on French speakers listening to French words suggested that the syllable functions as a segmentation unit in speech processing. However, while French has relatively regular and clearly bounded syllables, other languages, such as English, do not. No trace of syllabifying segmentation was found in English listeners listening to English words, French words, or nonsense words. French listeners, however, showed evidence of syllabification even when they were listening to English words. We conclude that alternative segmentation routines are available to the human language processor. In some cases speech segmentation may involve the operation of more than one procedure.
  • Cutler, A., & Henton, C. G. (2004). There's many a slip 'twixt the cup and the lip. In H. Quené, & V. Van Heuven (Eds.), On speech and Language: Studies for Sieb G. Nooteboom (pp. 37-45). Utrecht: Netherlands Graduate School of Linguistics.

    Abstract

    The retiring academic may look back upon, inter alia, years of conference attendance. Speech error researchers are uniquely fortunate because they can collect data in any situation involving communication; accordingly, the retiring speech error researcher will have collected data at those conferences. We here address the issue of whether error data collected in situations involving conviviality (such as at conferences) is representative of error data in general. Our approach involved a comparison, across three levels of linguistic processing, between a specially constructed Conviviality Sample and the largest existing source of speech error data, the newly available Fromkin Speech Error Database. The results indicate that there are grounds for regarding the data in the Conviviality Sample as a better than average reflection of the true population of all errors committed. These findings encourage us to recommend further data collection in collaboration with like-minded colleagues.
  • Cutler, A. (2004). Twee regels voor academische vorming. In H. Procee (Ed.), Bij die wereld wil ik horen! Zesendertig columns en drie essays over de vorming tot academicus. (pp. 42-45). Amsterdam: Boom.
  • Cutler, A., Demuth, K., & McQueen, J. M. (2002). Universality versus language-specificity in listening to running speech. Psychological Science, 13(3), 258-262. doi:10.1111/1467-9280.00447.

    Abstract

    Recognizing spoken language involves automatic activation of multiple candidate words. The process of selection between candidates is made more efficient by inhibition of embedded words (like egg in beg) that leave a portion of the input stranded (here, b). Results from European languages suggest that this inhibition occurs when consonants are stranded but not when syllables are stranded. The reason why leftover syllables do not lead to inhibition could be that in principle they might themselves be words; in European languages, a syllable can be a word. In Sesotho (a Bantu language), however, a single syllable cannot be a word. We report that in Sesotho, word recognition is inhibited by stranded consonants, but stranded monosyllables produce no more difficulty than stranded bisyllables (which could be Sesotho words). This finding suggests that the viability constraint which inhibits spurious embedded word candidates is not sensitive to language-specific word structure, but is universal.
  • Ip, M. H. K., & Cutler, A. (2020). Universals of listening: Equivalent prosodic entrainment in tone and non-tone languages. Cognition, 202: 104311. doi:10.1016/j.cognition.2020.104311.

    Abstract

    In English and Dutch, listeners entrain to prosodic contours to predict where focus will fall in an utterance. Here, we ask whether this strategy is universally available, even in languages with very different phonological systems (e.g., tone versus non-tone languages). In a phoneme detection experiment, we examined whether prosodic entrainment also occurs in Mandarin Chinese, a tone language, where the use of various suprasegmental cues to lexical identity may take precedence over their use in salience. Consistent with the results from Germanic languages, response times were facilitated when preceding intonation predicted high stress on the target-bearing word, and the lexical tone of the target word (i.e., rising versus falling) did not affect the Mandarin listeners' response. Further, the extent to which prosodic entrainment was used to detect the target phoneme was the same in both English and Mandarin listeners. Nevertheless, native Mandarin speakers did not adopt an entrainment strategy when the sentences were presented in English, consistent with the suggestion that L2 listening may be strained by additional functional load from prosodic processing. These findings have implications for how universal and language-specific mechanisms interact in the perception of focus structure in everyday discourse.

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  • Cutler, A. (2002). Lexical access. In L. Nadel (Ed.), Encyclopedia of cognitive science (pp. 858-864). London: Nature Publishing Group.
  • Cutler, A., Mister, E., Norris, D., & Sebastián-Gallés, N. (2004). La perception de la parole en espagnol: Un cas particulier? In L. Ferrand, & J. Grainger (Eds.), Psycholinguistique cognitive: Essais en l'honneur de Juan Segui (pp. 57-74). Brussels: De Boeck.
  • Cutler, A., McQueen, J. M., Norris, D., & Somejuan, A. (2002). Le rôle de la syllable. In E. Dupoux (Ed.), Les langages du cerveau: Textes en l’honneur de Jacques Mehler (pp. 185-197). Paris: Odile Jacob.
  • Cutler, A. (2002). Native listeners. European Review, 10(1), 27-41. doi:10.1017/S1062798702000030.

    Abstract

    Becoming a native listener is the necessary precursor to becoming a native speaker. Babies in the first year of life undertake a remarkable amount of work; by the time they begin to speak, they have perceptually mastered the phonological repertoire and phoneme co-occurrence probabilities of the native language, and they can locate familiar word-forms in novel continuous-speech contexts. The skills acquired at this early stage form a necessary part of adult listening. However, the same native listening skills also underlie problems in listening to a late-acquired non-native language, accounting for why in such a case listening (an innate ability) is sometimes paradoxically more difficult than, for instance, reading (a learned ability).
  • Cutler, A., & McQueen, J. M. (2014). How prosody is both mandatory and optional. In J. Caspers, Y. Chen, W. Heeren, J. Pacilly, N. O. Schiller, & E. Van Zanten (Eds.), Above and Beyond the Segments: Experimental linguistics and phonetics (pp. 71-82). Amsterdam: Benjamins.

    Abstract

    Speech signals originate as a sequence of linguistic units selected by speakers, but these units are necessarily realised in the suprasegmental dimensions of time, frequency and amplitude. For this reason prosodic structure has been viewed as a mandatory target of language processing by both speakers and listeners. In apparent contradiction, however, prosody has also been argued to be ancillary rather than core linguistic structure, making processing of prosodic structure essentially optional. In the present tribute to one of the luminaries of prosodic research for the past quarter century, we review evidence from studies of the processing of lexical stress and focal accent which reconciles these views and shows that both claims are, each in their own way, fully true.
  • Cutler, A. (2014). In thrall to the vocabulary. Acoustics Australia, 42, 84-89.

    Abstract

    Vocabularies contain hundreds of thousands of words built from only a handful of phonemes; longer words inevitably tend to contain shorter ones. Recognising speech thus requires distinguishing intended words from accidentally present ones. Acoustic information in speech is used wherever it contributes significantly to this process; but as this review shows, its contribution differs across languages, with the consequences of this including: identical and equivalently present information distinguishing the same phonemes being used in Polish but not in German, or in English but not in Italian; identical stress cues being used in Dutch but not in English; expectations about likely embedding patterns differing across English, French, Japanese.
  • Cutler, A. (2011). Listening to REAL second language. AATSEEL Newsletter, 54(3), 14.
  • Cutter, M. G., Martin, A. E., & Sturt, P. (2020). Capitalization interacts with syntactic complexity. Journal of Experimental Psychology: Learning, Memory, and Cognition, 46(6), 1146-1164. doi:10.1037/xlm0000780.

    Abstract

    We investigated whether readers use the low-level cue of proper noun capitalization in the parafovea to infer syntactic category, and whether this results in an early update of the representation of a sentence’s syntactic structure. Participants read sentences containing either a subject relative or object relative clause, in which the relative clause’s overt argument was a proper noun (e.g., The tall lanky guard who alerted Charlie/Charlie alerted to the danger was young) across three experiments. In Experiment 1 these sentences were presented in normal sentence casing or entirely in upper case. In Experiment 2 participants received either valid or invalid parafoveal previews of the relative clause. In Experiment 3 participants viewed relative clauses in only normal conditions. We hypothesized that we would observe relative clause effects (i.e., inflated fixation times for object relative clauses) while readers were still fixated on the word who, if readers use capitalization to infer a parafoveal word’s syntactic class. This would constitute a syntactic parafoveal-on-foveal effect. Furthermore, we hypothesised that this effect should be influenced by sentence casing in Experiment 1 (with no cue for syntactic category being available in upper case sentences) but not by parafoveal preview validity of the target words. We observed syntactic parafoveal-on-foveal effects in Experiment 1 and 3, and a Bayesian analysis of the combined data from all three experiments. These effects seemed to be influenced more by noun capitalization than lexical processing. We discuss our findings in relation to models of eye movement control and sentence processing theories.
  • Cutter, M. G., Martin, A. E., & Sturt, P. (2020). Readers detect an low-level phonological violation between two parafoveal words. Cognition, 204: 104395. doi:10.1016/j.cognition.2020.104395.

    Abstract

    In two eye-tracking studies we investigated whether readers can detect a violation of the phonological-grammatical convention for the indefinite article an to be followed by a word beginning with a vowel when these two words appear in the parafovea. Across two experiments participants read sentences in which the word an was followed by a parafoveal preview that was either correct (e.g. Icelandic), incorrect and represented a phonological violation (e.g. Mongolian), or incorrect without representing a phonological violation (e.g. Ethiopian), with this parafoveal preview changing to the target word as participants made a saccade into the space preceding an. Our data suggests that participants detected the phonological violation while the target word was still two words to the right of fixation, with participants making more regressions from the previewed word and having longer go-past times on this word when they received a violation preview as opposed to a non-violation preview. We argue that participants were attempting to perform aspects of sentence integration on the basis of low-level orthographic information from the previewed word.

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    Data files and R Scripts
  • Cutter, M. G., Martin, A. E., & Sturt, P. (2020). The activation of contextually predictable words in syntactically illegal positions. Quarterly Journal of Experimental Psychology, 73(9), 1423-1430. doi:10.1177/1747021820911021.

    Abstract

    We present an eye-tracking study testing a hypothesis emerging from several theories of prediction during language processing, whereby predictable words should be skipped more than unpredictable words even in syntactically illegal positions. Participants read sentences in which a target word became predictable by a certain point (e.g., “bone” is 92% predictable given, “The dog buried his. . .”), with the next word actually being an intensifier (e.g., “really”), which a noun cannot follow. The target noun remained predictable to appear later in the sentence. We used the boundary paradigm to present the predictable noun or an alternative unpredictable noun (e.g., “food”) directly after the intensifier, until participants moved beyond the intensifier, at which point the noun changed to a syntactically legal word. Participants also read sentences in which predictable or unpredictable nouns appeared in syntactically legal positions. A Bayesian linear-mixed model suggested a 5.7% predictability effect on skipping of nouns in syntactically legal positions, and a 3.1% predictability effect on skipping of nouns in illegal positions. We discuss our findings in relation to theories of lexical prediction during reading.

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    OSF data
  • Cychosz, M., Romeo, R., Soderstrom, M., Scaff, C., Ganek, H., Cristia, A., Casillas, M., De Barbaro, K., Bang, J. Y., & Weisleder, A. (2020). Longform recordings of everyday life: Ethics for best practices. Behavior Research Methods, 52, 1951-1969. doi:10.3758/s13428-020-01365-9.

    Abstract

    Recent advances in large-scale data storage and processing offer unprecedented opportunities for behavioral scientists to collect and analyze naturalistic data, including from under-represented groups. Audio data, particularly real-world audio recordings, are of particular interest to behavioral scientists because they provide high-fidelity access to subtle aspects of daily life and social interactions. However, these methodological advances pose novel risks to research participants and communities. In this article, we outline the benefits and challenges associated with collecting, analyzing, and sharing multi-hour audio recording data. Guided by the principles of autonomy, privacy, beneficence, and justice, we propose a set of ethical guidelines for the use of longform audio recordings in behavioral research. This article is also accompanied by an Open Science Framework Ethics Repository that includes informed consent resources such as frequent participant concerns and sample consent forms.
  • Dahan, D., & Tanenhaus, M. K. (2004). Continuous mapping from sound to meaning in spoken-language comprehension: Immediate effects of verb-based thematic constraints. Journal of Experimental Psychology: Learning, Memory, and Cognition, 30(2), 498-513. doi:10.1037/0278-7393.30.2.498.

    Abstract

    The authors used 2 “visual-world” eye-tracking experiments to examine lexical access using Dutch constructions in which the verb did or did not place semantic constraints on its subsequent subject noun phrase. In Experiment 1, fixations to the picture of a cohort competitor (overlapping with the onset of the referent’s name, the subject) did not differ from fixations to a distractor in the constraining-verb condition. In Experiment 2, cross-splicing introduced phonetic information that temporarily biased the input toward the cohort competitor. Fixations to the cohort competitor temporarily increased in both the neutral and constraining conditions. These results favor models in which mapping from the input onto meaning is continuous over models in which contextual effects follow access of an initial form-based competitor set.
  • Dahan, D., Tanenhaus, M. K., & Chambers, C. G. (2002). Accent and reference resolution in spoken-language comprehension. Journal of Memory and Language, 47(2), 292-314. doi:10.1016/S0749-596X(02)00001-3.

    Abstract

    The role of accent in reference resolution was investigated by monitoring eye fixations to lexical competitors (e.g., candy and candle ) as participants followed prerecorded instructions to move objects above or below fixed geometric shapes using a computer mouse. In Experiment 1, the first utterance instructed participants to move one object above or below a shape (e.g., “Put the candle/candy below the triangle”) and the second utterance contained an accented or deaccented definite noun phrase which referred to the same object or introduced a new entity (e.g., “Now put the CANDLE above the square” vs. “Now put the candle ABOVE THE SQUARE”). Fixations to the competitor (e.g., candy ) demonstrated a bias to interpret deaccented nouns as anaphoric and accented nouns as nonanaphoric. Experiment 2 used only accented nouns in the second instruction, varying whether the referent of this second instruction was the Theme of the first instruction (e.g., “Put the candle below the triangle”) or the Goal of the first instruction (e.g., “Put the necklace below the candle”). Participants preferred to interpret accented noun phrases as referring to a previously mentioned nonfocused entity (the Goal) rather than as introducing a new unmentioned entity.
  • Daller, M. H., Treffers-Daller, J., & Furman, R. (2011). Transfer of conceptualization patterns in bilinguals: The construal of motion events in Turkish and German. Bilingualism: Language and Cognition, 14(1), 95-119. doi:10.1017/S1366728910000106.

    Abstract

    In the present article we provide evidence for the occurrence of transfer of conceptualization patterns in narratives of two German-Turkish bilingual groups. All bilingual participants grew up in Germany, but only one group is still resident in Germany (n = 49). The other, the returnees, moved back to Turkey after having lived in Germany for thirteen years (n = 35). The study is based on the theoretical framework for conceptual transfer outlined in Jarvis and Pavlenko (2008) and on the typology of satellite-framed and verb-framed languages developed by Talmy (1985, 1991, 2000a, b) and Slobin (1987, 1996, 2003, 2004, 2005, 2006). In the present study we provide evidence for the hypothesis that language structure affects the organization of information structure at the level of the Conceptualizer, and show that bilingual speakers’ conceptualization of motion events is influenced by the dominant linguistic environment in both languages (German for the group in Germany and Turkish for the returnees). The returnees follow the Turkish blueprints for the conceptualization of motion, in both Turkish and German event construals, whereas the German-resident bilinguals follow the German blueprints, when speaking German as well as Turkish. We argue that most of the patterns found are the result of transfer of conceptualization patterns from the dominant language of the environment.
  • Daly, T., Chen, X. S., & Penny, D. (2011). How old are RNA networks? In L. J. Collins (Ed.), RNA infrastructure and networks (pp. 255-273). New York: Springer Science + Business Media and Landes Bioscience.

    Abstract

    Some major classes of RNAs (such as mRNA, rRNA, tRNA and RNase P) are ubiquitous in all living systems so are inferred to have arisen early during the origin of life. However, the situation is not so clear for the system of RNA regulatory networks that continue to be uncovered, especially in eukaryotes. It is increasingly being recognised that networks of small RNAs are important for regulation in all cells, but it is not certain whether the origin of these networks are as old as rRNAs and tRNA. Another group of ncRNAs, including snoRNAs, occurs mainly in archaea and eukaryotes and their ultimate origin is less certain, although perhaps the simplest hypothesis is that they were present in earlier stages of life and were lost from bacteria. Some RNA networks may trace back to an early stage when there was just RNA and proteins, the RNP‑world; before DNA.
  • Danielsen, S., Dunn, M., & Muysken, P. (2011). The spread of the Arawakan languages: A view from structural phylogenetics. In A. Hornborg, & J. D. Hill (Eds.), Ethnicity in ancient Amazonia: Reconstructing past identities from archaeology, linguistics, and ethnohistory (pp. 173-196). Boulder: University Press of Colorado.
  • Dautriche, I., Cristia, A., Brusini, P., Yuan, S., Fisher, C., & Christophe, A. (2014). Toddlers default to canonical surface-to-meaning mapping when learning verbs. Child Development, 85(3), 1168-1180. doi:10.1111/cdev.12183.

    Abstract

    This work was supported by grants from the French Agence Nationale de la Recherche (ANR-2010-BLAN-1901) and from French Fondation de France to Anne Christophe, from the National Institute of Child Health and Human Development (HD054448) to Cynthia Fisher, Fondation Fyssen and Ecole de Neurosciences de Paris to Alex Cristia, and a PhD fellowship from the Direction Générale de l'Armement (DGA, France) supported by the PhD program FdV (Frontières du Vivant) to Isabelle Dautriche. We thank Isabelle Brunet for the recruitment, Michel Dutat for the technical support, and Hernan Anllo for his puppet mastery skill. We are grateful to the families that participated in this study. We also thank two anonymous reviewers for their comments on an earlier draft of this manuscript.
  • Davids, N., Segers, E., Van den Brink, D., Mitterer, H., van Balkom, H., Hagoort, P., & Verhoeven, L. (2011). The nature of auditory discrimination problems in children with specific language impairment: An MMN study. Neuropsychologia, 49, 19-28. doi:10.1016/j.neuropsychologia.2010.11.001.

    Abstract

    Many children with Specific Language Impairment (SLI) show impairments in discriminating auditorily presented stimuli. The present study investigates whether these discrimination problems are speech specific or of a general auditory nature. This was studied by using a linguistic and nonlinguistic contrast that were matched for acoustic complexity in an active behavioral task and a passive ERP paradigm, known to elicit the mismatch negativity (MMN). In addition, attention skills and a variety of language skills were measured. Participants were 25 five-year-old Dutch children with SLI having receptive as well as productive language problems and 25 control children with typical speechand language development. At the behavioral level, the SLI group was impaired in discriminating the linguistic contrast as compared to the control group, while both groups were unable to distinguish the non-linguistic contrast. Moreover, the SLI group tended to have impaired attention skills which correlated with performance on most of the language tests. At the neural level, the SLI group, in contrast to the control group, did not show an MMN in response to either the linguistic or nonlinguistic contrast. The MMN data are consistent with an account that relates the symptoms in children with SLI to non-speech processing difficulties.
  • Davidson, D., & Indefrey, P. (2011). Error-related activity and correlates of grammatical plasticity. Frontiers in Psychology, 2: 219. doi:10.3389/fpsyg.2011.00219.

    Abstract

    Cognitive control involves not only the ability to manage competing task demands, but also the ability to adapt task performance during learning. This study investigated how violation-, response-, and feedback-related electrophysiological (EEG) activity changes over time during language learning. Twenty-two Dutch learners of German classified short prepositional phrases presented serially as text. The phrases were initially presented without feedback during a pre-test phase, and then with feedback in a training phase on two separate days spaced 1 week apart. The stimuli included grammatically correct phrases, as well as grammatical violations of gender and declension. Without feedback, participants' classification was near chance and did not improve over trials. During training with feedback, behavioral classification improved and violation responses appeared to both types of violation in the form of a P600. Feedback-related negative and positive components were also present from the first day of training. The results show changes in the electrophysiological responses in concert with improving behavioral discrimination, suggesting that the activity is related to grammar learning.
  • Davies, C., McGillion, M., Rowland, C. F., & Matthews, D. (2020). Can inferencing be trained in preschoolers using shared book-reading? A randomised controlled trial of parents’ inference-eliciting questions on oral inferencing ability. Journal of Child Language, 47(3), 655-679. doi:10.1017/S0305000919000801.

    Abstract

    The ability to make inferences is essential for effective language comprehension. While inferencing training benefits reading comprehension in school-aged children (see Elleman, 2017, for a review), we do not yet know whether it is beneficial to support the development of these skills prior to school entry. In a pre-registered randomised controlled trial, we evaluated the efficacy of a parent-delivered intervention intended to promote four-year-olds’ oral inferencing skills during shared book-reading. One hundred children from socioeconomically diverse backgrounds were randomly assigned to inferencing training or an active control condition of daily maths activities. The training was found to have no effect on inferencing. However, inferencing measures were highly correlated with children's baseline language ability. This suggests that a more effective approach to scaffolding inferencing in the preschool years might be to focus on promoting vocabulary to develop richer and stronger semantic networks.
  • Dediu, D. (2011). Are languages really independent from genes? If not, what would a genetic bias affecting language diversity look like? Human Biology, 83, 279-296. doi:10.3378/027.083.0208.

    Abstract

    It is generally accepted that the relationship between human genes
    and language is very complex and multifaceted. This has its roots in the
    “regular” complexity governing the interplay among genes and between genes
    and environment for most phenotypes, but with the added layer of supraontogenetic
    and supra-individual processes defining culture. At the coarsest
    level, focusing on the species, it is clear that human-specific—but not necessarily
    faculty-specific—genetic factors subtend our capacity for language and a
    currently very productive research program is aiming at uncovering them. At the
    other end of the spectrum, it is uncontroversial that individual-level variations in
    different aspects related to speech and language have an important genetic
    component and their discovery and detailed characterization have already started
    to revolutionize the way we think about human nature. However, at the
    intermediate, glossogenetic/population level, the relationship becomes controversial,
    partly due to deeply ingrained beliefs about language acquisition and
    universality and partly because of confusions with a different type of genelanguages
    correlation due to shared history. Nevertheless, conceptual, mathematical
    and computational models—and, recently, experimental evidence from
    artificial languages and songbirds—have repeatedly shown that genetic biases
    affecting the acquisition or processing of aspects of language and speech can be
    amplified by population-level intergenerational cultural processes and made
    manifest either as fixed “universal” properties of language or as structured
    linguistic diversity. Here, I review several such models as well as the recently
    proposed case of a causal relationship between the distribution of tone languages
    and two genes related to brain growth and development, ASPM and Microcephalin,
    and I discuss the relevance of such genetic biasing for language
    evolution, change, and diversity.
  • Dediu, D. (2011). A Bayesian phylogenetic approach to estimating the stability of linguistic features and the genetic biasing of tone. Proceedings of the Royal Society of London/B, 278(1704), 474-479. doi:10.1098/rspb.2010.1595.

    Abstract

    Language is a hallmark of our species and understanding linguistic diversity is an area of major interest. Genetic factors influencing the cultural transmission of language provide a powerful and elegant explanation for aspects of the present day linguistic diversity and a window into the emergence and evolution of language. In particular, it has recently been proposed that linguistic tone—the usage of voice pitch to convey lexical and grammatical meaning—is biased by two genes involved in brain growth and development, ASPM and Microcephalin. This hypothesis predicts that tone is a stable characteristic of language because of its ‘genetic anchoring’. The present paper tests this prediction using a Bayesian phylogenetic framework applied to a large set of linguistic features and language families, using multiple software implementations, data codings, stability estimations, linguistic classifications and outgroup choices. The results of these different methods and datasets show a large agreement, suggesting that this approach produces reliable estimates of the stability of linguistic data. Moreover, linguistic tone is found to be stable across methods and datasets, providing suggestive support for the hypothesis of genetic influences on its distribution.
  • Dediu, D., & Graham, S. A. (2014). Genetics and Language. In M. Aronoff (Ed.), Oxford Bibliographies in Linguistics. New York: Oxford University Press. Retrieved from http://www.oxfordbibliographies.com/view/document/obo-9780199772810/obo-9780199772810-0184.xml.

    Abstract

    This article surveys what is currently known about the complex interplay between genetics and the language sciences. It focuses not only on the genetic architecture of language and speech, but also on their interactions on the cultural and evolutionary timescales. Given the complexity of these issues and their current state of flux and high dynamism, this article surveys the main findings and topics of interest while also briefly introducing the main relevant methods, thus allowing the interested reader to fully appreciate and understand them in their proper context. Of course, not all the relevant publications and resources are mentioned, but this article aims to select the most relevant, promising, or accessible for nonspecialists.

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  • Dediu, D. (2014). Language and biology: The multiple interactions between genetics and language. In N. J. Enfield, P. Kockelman, & J. Sidnell (Eds.), The Cambridge handbook of linguistic anthropology (pp. 686-707). Cambridge: Cambridge University Press.
  • Dediu, D., & Levinson, S. C. (2014). The time frame of the emergence of modern language and its implications. In D. Dor, C. Knight, & J. Lewis (Eds.), The social origins of language (pp. 184-195). Oxford: Oxford University Press.
  • Defina, R. (2014). Arbil: Free tool for creating, editing and searching metadata. Language Documentation and Conservation, 8, 307-314.
  • Dempsey, J., & Brehm, L. (2020). Can propositional biases modulate syntactic repair processes? Insights from preceding comprehension questions. Journal of Cognitive Psychology, 32(5-6), 543-552. doi:10.1080/20445911.2020.1803884.

    Abstract

    There is an ongoing debate about whether discourse biases can constrain sentence
    processing. Previous work has shown comprehension question accuracy to decrease
    for temporarily ambiguous sentences preceded by a context biasing towards an initial
    misinterpretation, suggesting a role of context for modulating comprehension.
    However, this creates limited modulation of reading times at the disambiguating word,
    suggesting initial syntactic processing may be unaffected by context [Christianson &
    Luke, 2011. Context strengthens initial misinterpretations of text. Scientific Studies of
    Reading, 15(2), 136–166]. The current experiments examine whether propositional and
    structural content from preceding comprehension questions can cue readers to expect
    certain structures in temporarily ambiguous garden-path sentences. The central finding
    is that syntactic repair processes remain unaffected while reading times in other
    regions are modulated by preceding questions. This suggests that reading strategies
    can be superficially influenced by preceding comprehension questions without
    impacting the fidelity of ultimate (mis)representations.

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    pecp_a_1803884_sm1217.zip
  • Den Os, E., & Boves, L. (2002). BabelWeb project develops multilingual guidelines. Multilingual Computing and Technologies, 13(1), 33-36.

    Abstract

    European cooperative effort seeks best practices architecture and procedures for international sites
  • Den Os, E., & Boves, L. (2004). Natural multimodal interaction for design applications. In P. Cunningham (Ed.), Adoption and the knowledge economy (pp. 1403-1410). Amsterdam: IOS Press.
  • Den Hoed, J., & Fisher, S. E. (2020). Genetic pathways involved in human speech disorders. Current Opinion in Genetics & Development, 65, 103-111. doi:10.1016/j.gde.2020.05.012.
  • Deriziotis, P., O'Roak, B. J., Graham, S. A., Estruch, S. B., Dimitropoulou, D., Bernier, R. A., Gerdts, J., Shendure, J., Eichler, E. E., & Fisher, S. E. (2014). De novo TBR1 mutations in sporadic autism disrupt protein functions. Nature Communications, 5: 4954. doi:10.1038/ncomms5954.

    Abstract

    Next-generation sequencing recently revealed that recurrent disruptive mutations in a few genes may account for 1% of sporadic autism cases. Coupling these novel genetic data to empirical assays of protein function can illuminate crucial molecular networks. Here we demonstrate the power of the approach, performing the first functional analyses of TBR1 variants identified in sporadic autism. De novo truncating and missense mutations disrupt multiple aspects of TBR1 function, including subcellular localization, interactions with co-regulators and transcriptional repression. Missense mutations inherited from unaffected parents did not disturb function in our assays. We show that TBR1 homodimerizes, that it interacts with FOXP2, a transcription factor implicated in speech/language disorders, and that this interaction is disrupted by pathogenic mutations affecting either protein. These findings support the hypothesis that de novo mutations in sporadic autism have severe functional consequences. Moreover, they uncover neurogenetic mechanisms that bridge different neurodevelopmental disorders involving language deficits.
  • Deriziotis, P., André, R., Smith, D. M., Goold, R., Kinghorn, K. J., Kristiansen, M., Nathan, J. A., Rosenzweig, R., Krutauz, D., Glickman, M. H., Collinge, J., Goldberg, A. L., & Tabrizi, S. J. (2011). Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry. EMBO Journal, 30(15), 3065-3077. doi:10.1038/emboj.2011.224.

    Abstract

    * Deriziotis, P., André, R., and Smith. D.M. contributed equally to this work * - Prion diseases are associated with the conversion of cellular prion protein (PrP(C)) to toxic β-sheet isoforms (PrP(Sc)), which are reported to inhibit the ubiquitin-proteasome system (UPS). Accordingly, UPS substrates accumulate in prion-infected mouse brains, suggesting impairment of the 26S proteasome. A direct interaction between its 20S core particle and PrP isoforms was demonstrated by immunoprecipitation. β-PrP aggregates associated with the 20S particle, but did not impede binding of the PA26 complex, suggesting that the aggregates do not bind to its ends. Aggregated β-PrP reduced the 20S proteasome's basal peptidase activity, and the enhanced activity induced by C-terminal peptides from the 19S ATPases or by the 19S regulator itself, including when stimulated by polyubiquitin conjugates. However, the 20S proteasome was not inhibited when the gate in the α-ring was open due to a truncation mutation or by association with PA26/PA28. These PrP aggregates inhibit by stabilising the closed conformation of the substrate entry channel. A similar inhibition of substrate entry into the proteasome may occur in other neurodegenerative diseases where misfolded β-sheet-rich proteins accumulate.

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    EMBOsup.pdf
  • Deriziotis, P., Graham, S. A., Estruch, S. B., & Fisher, S. E. (2014). Investigating protein-protein interactions in live cells using Bioluminescence Resonance Energy Transfer. Journal of visualized experiments, 87: e51438. doi:10.3791/51438.

    Abstract

    Assays based on Bioluminescence Resonance Energy Transfer (BRET) provide a sensitive and reliable means to monitor protein-protein interactions in live cells. BRET is the non-radiative transfer of energy from a ‘donor’ luciferase enzyme to an ‘acceptor’ fluorescent protein. In the most common configuration of this assay, the donor is Renilla reniformis luciferase and the acceptor is Yellow Fluorescent Protein (YFP). Because the efficiency of energy transfer is strongly distance-dependent, observation of the BRET phenomenon requires that the donor and acceptor be in close proximity. To test for an interaction between two proteins of interest in cultured mammalian cells, one protein is expressed as a fusion with luciferase and the second as a fusion with YFP. An interaction between the two proteins of interest may bring the donor and acceptor sufficiently close for energy transfer to occur. Compared to other techniques for investigating protein-protein interactions, the BRET assay is sensitive, requires little hands-on time and few reagents, and is able to detect interactions which are weak, transient, or dependent on the biochemical environment found within a live cell. It is therefore an ideal approach for confirming putative interactions suggested by yeast two-hybrid or mass spectrometry proteomics studies, and in addition it is well-suited for mapping interacting regions, assessing the effect of post-translational modifications on protein-protein interactions, and evaluating the impact of mutations identified in patient DNA.

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  • Devanna, P., & Vernes, S. C. (2014). A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137. Scientific Reports, 4: 3994. doi:10.1038/srep03994.

    Abstract

    Retinoic acid-related orphan receptor alpha gene (RORa) and the microRNA MIR137 have both recently been identified as novel candidate genes for neuropsychiatric disorders. RORa encodes a ligand-dependent orphan nuclear receptor that acts as a transcriptional regulator and miR-137 is a brain enriched small non-coding RNA that interacts with gene transcripts to control protein levels. Given the mounting evidence for RORa in autism spectrum disorders (ASD) and MIR137 in schizophrenia and ASD, we investigated if there was a functional biological relationship between these two genes. Herein, we demonstrate that miR-137 targets the 3'UTR of RORa in a site specific manner. We also provide further support for MIR137 as an autism candidate by showing that a large number of previously implicated autism genes are also putatively targeted by miR-137. This work supports the role of MIR137 as an ASD candidate and demonstrates a direct biological link between these previously unrelated autism candidate genes
  • Devanna, P., Middelbeek, J., & Vernes, S. C. (2014). FOXP2 drives neuronal differentiation by interacting with retinoic acid signaling pathways. Frontiers in Cellular Neuroscience, 8: 305. doi:10.3389/fncel.2014.00305.

    Abstract

    FOXP2 was the first gene shown to cause a Mendelian form of speech and language disorder. Although developmentally expressed in many organs, loss of a single copy of FOXP2 leads to a phenotype that is largely restricted to orofacial impairment during articulation and linguistic processing deficits. Why perturbed FOXP2 function affects specific aspects of the developing brain remains elusive. We investigated the role of FOXP2 in neuronal differentiation and found that FOXP2 drives molecular changes consistent with neuronal differentiation in a human model system. We identified a network of FOXP2 regulated genes related to retinoic acid signaling and neuronal differentiation. FOXP2 also produced phenotypic changes associated with neuronal differentiation including increased neurite outgrowth and reduced migration. Crucially, cells expressing FOXP2 displayed increased sensitivity to retinoic acid exposure. This suggests a mechanism by which FOXP2 may be able to increase the cellular differentiation response to environmental retinoic acid cues for specific subsets of neurons in the brain. These data demonstrate that FOXP2 promotes neuronal differentiation by interacting with the retinoic acid signaling pathway and regulates key processes required for normal circuit formation such as neuronal migration and neurite outgrowth. In this way, FOXP2, which is found only in specific subpopulations of neurons in the brain, may drive precise neuronal differentiation patterns and/or control localization and connectivity of these FOXP2 positive cells
  • Dimroth, C. (2002). Topics, assertions and additive words: How L2 learners get from information structure to target-language syntax. Linguistics, 40(4), 891-923. doi:10.1515/ling.2002.033.

    Abstract

    The article compares the integration of topic-related additive words at different stages of untutored L2 acquisition. Data stem from an ‘‘additive-elicitation task’’ that was designed in order to capture topic-related additive words in a context that is at the same time controlled for the underlying information structure and nondeviant from other kinds of narrative discourse. We relate the distinction between stressed and nonstressed forms of the German scope particles and adverbials auch ‘also’, noch ‘another’, wieder ‘again’, and immer noch ‘still’ to a uniform, information-structure-based principle: the stressed variants have scope over the topic information of the relevant utterances. It is then the common function of these additive words to express the additive link between the topic of the present utterance and some previous topic for which the same state of affairs is claimed to hold. This phenomenon has often been referred to as ‘‘contrastive topic,’’ but contrary to what this term suggests, these topic elements are by no means deviant from the default in coherent discourse. In the underlying information structure, the validity of some given state of affairs for the present topic must be under discussion. Topic-related additive words then express that the state of affairs indeed applies to this topic, their function therefore coming close to the function of assertion marking. While this functional correspondence goes along with the formal organization of the basic stages of untutored second-language acquisition, its expression brings linguistic constraints into conflict when the acquisition of finiteness pushes learners to reorganize their utterances according to target-language syntax.
  • Dimroth, C., & Lasser, I. (2002). Finite options: How L1 and L2 learners cope with the acquisition of finiteness. Linguistics, 40(4), 647-651. doi:10.1515/ling.2002.027.
  • Dingemanse, M., & Enfield, N. J. (2014). Ongeschreven regels van de taal. Psyche en Brein, 6, 6-11.

    Abstract

    Als je wereldwijd gesprekken beluistert, merk je dat de menselijke dialoog universele regels volgt. Die sturen en verrijken onze sociale interactie.
  • Dingemanse, M., Perlman, M., & Perniss, P. (2020). Construals of iconicity: Experimental approaches to form-meaning resemblances in language. Language and Cognition, 12(1), 1-14. doi:10.1017/langcog.2019.48.

    Abstract

    While speculations on form–meaning resemblances in language go back millennia, the experimental study of iconicity is only about a century old. Here we take stock of experimental work on iconicity and present a double special issue with a diverse set of new contributions. We contextualise the work by introducing a typology of approaches to iconicity in language. Some approaches construe iconicity as a discrete property that is either present or absent; others treat it as involving semiotic relationships that come in kinds; and yet others see it as a gradient substance that comes in degrees. We show the benefits and limitations that come with each of these construals and stress the importance of developing accounts that can fluently switch between them. With operationalisations of iconicity that are well defined yet flexible enough to deal with differences in tasks, modalities, and levels of analysis, experimental research on iconicity is well equipped to contribute to a comprehensive science of language.
  • Dingemanse, M. (2020). Resource-rationality beyond individual minds: The case of interactive language use. Behavioral and Brain Sciences, 43, 23-24. doi:10.1017/S0140525X19001638.

    Abstract

    Resource-rational approaches offer much promise for understanding human cognition, especially if they can reach beyond the confines of individual minds. Language allows people to transcend individual resource limitations by augmenting computation and enabling distributed cognition. Interactive language use, an environment where social rational agents routinely deal with resource constraints together, offers a natural laboratory to test resource-rationality in the wild.
  • Dingemanse, M. (2020). Between sound and speech: Liminal signs in interaction. Research on Language and Social Interaction, 53(1), 188-196. doi:10.1080/08351813.2020.1712967.

    Abstract

    When people talk, they recruit a wide range of expressive devices for interactional work, from sighs, sniffs, clicks, and whistles to other conduct that borders on the linguistic. These resources represent some of the more elusive yet no less powerful aspects of the interactional machinery as they are used in the management of turn and sequence and the marking of stance and affect. Phenomena long assumed to be beyond the purview of linguistic inquiry emerge as systematically deployed practices whose ambiguous degree of control and convention allows participants to carry out subtle interactional work without committing to specific words. While these resources have been characterised as non-lexical, non-verbal, or non-conventional, I propose they are unified in their liminality: they work well precisely because they equivocate between sound and speech. The empirical study of liminal signs shows the promise of sequential analysis for building a science of language on interactional foundations.
  • Dingemanse, M., & Floyd, S. (2014). Conversation across cultures. In N. J. Enfield, P. Kockelman, & J. Sidnell (Eds.), The Cambridge handbook of linguistic anthropology (pp. 447-480). Cambridge: Cambridge University Press.
  • Dingemanse, M. (2020). Der Raum zwischen unseren Köpfen. Technology Review, 2020(13), 10-15.

    Abstract

    Aktuelle Vorstellungen von Gehirn-zu-Gehirn-Schnittstellen versprechen, die Sprache zu umgehen. Aber wenn wir sie verfeinern, um ihr kollaboratives Potenzial voll auszuschöpfen, sehen wir Sprache — oder zumindest ein sprachähnliches Infrastruktur für Kommunika­tion und Koordination — durch die Hintertür wieder hereinkommen. Es wäre nicht das erste Mal, dass sich die Sprache neu erfindet.

    Current conceptions of brain-to-brain interfaces attempt to bypass language. But when we refine them to more fully realise their collaborative potential we find language —or at least a language-like infrastructure for communication and coordination— slipping through the back door. It wouldn't be the first time that language reinvented itself.
  • Dingemanse, M., Van Leeuwen, T., & Majid, A. (2011). Mapping across senses: Two cross-modal association tasks. In K. Kendrick, & A. Majid (Eds.), Field manual volume 14 (pp. 11-15). Nijmegen: Max Planck Institute for Psycholinguistics. doi:10.17617/2.1005579.
  • Dingemanse, M. (2011). Ezra Pound among the Mawu: Ideophones and iconicity in Siwu. In P. Michelucci, O. Fischer, & C. Ljungberg (Eds.), Semblance and Signification (pp. 39-54). Amsterdam: John Benjamins.

    Abstract

    The Mawu people of eastern Ghana make common use of ideophones: marked words that depict sensory imagery. Ideophones have been described as “poetry in ordinary language,” yet the shadow of Lévy-Bruhl, who assigned such words to the realm of primitivity, has loomed large over linguistics and literary theory alike. The poet Ezra Pound is a case in point: while his fascination with Chinese characters spawned the ideogrammic method, the mimicry and gestures of the “primitive languages in Africa” were never more than a mere curiosity to him. This paper imagines Pound transposed into the linguaculture of the Mawu. What would have struck him about their ways of ‘charging language’ with imagery? I juxtapose Pound’s views of the poetic image with an analysis of how different layers of iconicity in ideophones combine to depict sensory imagery. This exercise illuminates aspects of what one might call ‘the ideophonic
  • Dingemanse, M., Blythe, J., & Dirksmeyer, T. (2014). Formats for other-initiation of repair across languages: An exercise in pragmatic typology. Studies in Language, 38, 5-43. doi:10.1075/sl.38.1.01din.

    Abstract

    In conversation, people have to deal with problems of speaking, hearing, and understanding. We report on a cross-linguistic investigation of the conversational structure of other-initiated repair (also known as collaborative repair, feedback, requests for clarification, or grounding sequences). We take stock of formats for initiating repair across languages (comparable to English huh?, who?, y’mean X?, etc.) and find that different languages make available a wide but remarkably similar range of linguistic resources for this function. We exploit the patterned variation as evidence for several underlying concerns addressed by repair initiation: characterising trouble, managing responsibility, and handling knowledge. The concerns do not always point in the same direction and thus provide participants in interaction with alternative principles for selecting one format over possible others. By comparing conversational structures across languages, this paper contributes to pragmatic typology: the typology of systems of language use and the principles that shape them
  • Dingemanse, M. (2011). Ideophones and the aesthetics of everyday language in a West-African society. The Senses & Society, 6(1), 77-85. doi:10.2752/174589311X12893982233830.

    Abstract

    This article explores language, culture, and the perceptual world as reflected in a particular linguistic device: ideophones, marked words that depict sensory imagery. Data from a range of elicitation tasks shows that ideophones are a key resource in talking about sensory perception in Siwu. Their use in everyday conversations underlines their communicative versatility while at the same time showing that people delight in their expressiveness. In ideophones, we have an expressive resource that combines sheer playfulness with extraordinary precision
  • Dingemanse, M. (2014). Making new ideophones in Siwu: Creative depiction in conversation. Pragmatics and Society, 5(3), 384-405. doi:10.1075/ps.5.3.04din.

    Abstract

    Ideophones are found in many of the world’s languages. Though they are a major word class on a par with nouns and verbs, their origins are ill-understood, and the question of ideophone creation has been a source of controversy. This paper studies ideophone creation in naturally occurring speech. New, unconventionalised ideophones are identified using native speaker judgements, and are studied in context to understand the rules and regularities underlying their production and interpretation. People produce and interpret new ideophones with the help of the semiotic infrastructure that underlies the use of existing ideophones: foregrounding frames certain stretches of speech as depictive enactments of sensory imagery, and various types of iconicity link forms and meanings. As with any creative use of linguistic resources, context and common ground also play an important role in supporting rapid ‘good enough’ interpretations of new material. The making of new ideophones is a special case of a more general phenomenon of creative depiction: the art of presenting verbal material in such a way that the interlocutor recognises and interprets it as a depiction.
  • Dingemanse, M., & Enfield, N. J. (2014). Let's talk: Universal social rules underlie languages. Scientific American Mind, 25, 64-69. doi:10.1038/scientificamericanmind0914-64.

    Abstract

    Recent developments in the science of language signal the emergence of a new paradigm for language study: a social approach to the fundamental questions of what language is like, how much languages really have in common, and why only our species has it. The key to these developments is a new appreciation of the need to study everyday spoken language, with all its complications and ‘imperfections’, in a systematic way. The work reviewed in this article —on turn-taking, timing, and other-initiated repair in languages around the world— has important implications for our understanding of human sociality and sheds new light on the social shape of language. For the first time in the history of linguistics, we are no longer tied to what can be written down or thought up. Rather, we look at language as a biologist would: as it occurs in nature.
  • Dingemanse, M. (2020). Recruiting assistance and collaboration: A West-African corpus study. In S. Floyd, G. Rossi, & N. J. Enfield (Eds.), Getting others to do things: A pragmatic typology of recruitments (pp. 369-241). Berlin: Language Science Press. doi:10.5281/zenodo.4018388.

    Abstract

    Doing things for and with others is one of the foundations of human social life. This chapter studies a systematic collection of 207 requests for assistance and collaboration from a video corpus of everyday conversations in Siwu, a Kwa language of Ghana. A range of social action formats and semiotic resources reveals how language is adapted to the interactional challenges posed by recruiting assistance. While many of the formats bear a language-specific signature, their sequential and interactional properties show important commonalities across languages. Two tentative findings are put forward for further cross-linguistic examination: a “rule of three” that may play a role in the organisation of successive response pursuits, and a striking commonality in animal-oriented recruitments across languages that may be explained by convergent cultural evolution. The Siwu recruitment system emerges as one instance of a sophisticated machinery for organising collaborative action that transcends language and culture.
  • Dingemanse, M., & Thompson, B. (2020). Playful iconicity: Structural markedness underlies the relation between funniness and iconicity. Language and Cognition, 12(1), 203-224. doi:10.1017/langcog.2019.49.

    Abstract

    Words like ‘waddle’, ‘flop’ and ‘zigzag’ combine playful connotations with iconic form-meaning resemblances. Here we propose that structural markedness may be a common factor underlying perceptions of playfulness and iconicity. Using collected and estimated lexical ratings covering a total of over 70,000 English words, we assess the robustness of this assocation. We identify cues of phonotactic complexity that covary with funniness and iconicity ratings and that, we propose, serve as metacommunicative signals to draw attention to words as playful and performative. To assess the generalisability of the findings we develop a method to estimate lexical ratings from distributional semantics and apply it to a dataset 20 times the size of the original set of human ratings. The method can be used more generally to extend coverage of lexical ratings. We find that it reliably reproduces correlations between funniness and iconicity as well as cues of structural markedness, though it also amplifies biases present in the human ratings. Our study shows that the playful and the poetic are part of the very texture of the lexicon.
  • Dolscheid, S., Çelik, S., Erkan, H., Küntay, A., & Majid, A. (2020). Space-pitch associations differ in their susceptibility to language. Cognition, 196: 104073. doi:10.1016/j.cognition.2019.104073.

    Abstract

    To what extent are links between musical pitch and space universal, and to what extent are they shaped by
    language? There is contradictory evidence in support of both universality and linguistic relativity presently,
    leaving the question open. To address this, speakers of Dutch who talk about pitch in terms of spatial height and
    speakers of Turkish who use a thickness metaphor were tested in simple nonlinguistic space-pitch association
    tasks. Both groups showed evidence of a thickness-pitch association, but differed significantly in their heightpitch
    associations, suggesting the latter may be more susceptible to language. When participants had to match
    pitches to spatial stimuli where height and thickness were opposed (i.e., a thick line high in space vs. a thin line
    low in space), Dutch and Turkish differed in their relative preferences. Whereas Turkish participants predominantly
    opted for a thickness-pitch interpretation—even if this meant a reversal of height-pitch
    mappings—Dutch participants favored a height-pitch interpretation more often. These findings provide new
    evidence that speakers of different languages vary in their space-pitch associations, while at the same time
    showing such associations are not equally susceptible to linguistic influences. Some space-pitch (i.e., heightpitch)
    associations are more malleable than others (i.e., thickness-pitch).
  • Dolscheid, S., Hunnius, S., Casasanto, D., & Majid, A. (2014). Prelinguistic infants are sensitive to space-pitch associations found across cultures. Psychological Science, 25(6), 1256-1261. doi:10.1177/0956797614528521.

    Abstract

    People often talk about musical pitch using spatial metaphors. In English, for instance, pitches can be “high” or “low” (i.e., height-pitch association), whereas in other languages, pitches are described as “thin” or “thick” (i.e., thickness-pitch association). According to results from psychophysical studies, metaphors in language can shape people’s nonlinguistic space-pitch representations. But does language establish mappings between space and pitch in the first place, or does it only modify preexisting associations? To find out, we tested 4-month-old Dutch infants’ sensitivity to height-pitch and thickness-pitch mappings using a preferential-looking paradigm. The infants looked significantly longer at cross-modally congruent stimuli for both space-pitch mappings, which indicates that infants are sensitive to these associations before language acquisition. The early presence of space-pitch mappings means that these associations do not originate from language. Instead, language builds on preexisting mappings, changing them gradually via competitive associative learning. Space-pitch mappings that are language-specific in adults develop from mappings that may be universal in infants.
  • Donnelly, S., & Kidd, E. (2020). Individual differences in lexical processing efficiency and vocabulary in toddlers: A longitudinal investigation. Journal of Experimental Child Psychology, 192: 104781. doi:10.1016/j.jecp.2019.104781.

    Abstract

    Research on infants’ online lexical processing by Fernald, Perfors, and Marchman (2006) revealed substantial individual differences that are related to vocabulary development, such that infants with better lexical processing efficiency show greater vocabulary growth across time. Although it is clear that individual differences in lexical processing efficiency exist and are meaningful, the theoretical nature of lexical processing efficiency and its relation to vocabulary size is less clear. In the current study, we asked two questions: (a) Is lexical processing efficiency better conceptualized as a central processing capacity or as an emergent capacity reflecting a collection of word-specific capacities? and (b) Is there evidence for a causal role for lexical processing efficiency in early vocabulary development? In the study, 120 infants were tested on a measure of lexical processing at 18, 21, and 24 months, and their vocabulary was measured via parent report. Structural equation modeling of the 18-month time point data revealed that both theoretical constructs represented in the first question above (a) fit the data. A set of regression analyses on the longitudinal data revealed little evidence for a causal effect of lexical processing on vocabulary but revealed a significant effect of vocabulary size on lexical processing efficiency early in development. Overall, the results suggest that lexical processing efficiency is a stable construct in infancy that may reflect the structure of the developing lexicon.
  • Doust, C., Gordon, S. D., Garden, N., Fisher, S. E., Martin, N. G., Bates, T. C., & Luciano, M. (2020). The association of dyslexia and developmental speech and language disorder candidate genes with reading and language abilities in adults. Twin Research and Human Genetics, 23(1), 22-32. doi:10.1017/thg.2020.7.

    Abstract

    Reading and language abilities are critical for educational achievement and success in adulthood. Variation in these traits is highly heritable, but the underlying genetic architecture is largely undiscovered. Genetic studies of reading and language skills traditionally focus on children with developmental disorders; however, much larger unselected adult samples are available, increasing power to identify associations with specific genetic variants of small effect size. We introduce an Australian adult population cohort (41.7–73.2 years of age, N = 1505) in which we obtained data using validated measures of several aspects of reading and language abilities. We performed genetic association analysis for a reading and spelling composite score, nonword reading (assessing phonological processing: a core component in learning to read), phonetic spelling, self-reported reading impairment and nonword repetition (a marker of language ability). Given the limited power in a sample of this size (~80% power to find a minimum effect size of 0.005), we focused on analyzing candidate genes that have been associated with dyslexia and developmental speech and language disorders in prior studies. In gene-based tests, FOXP2, a gene implicated in speech/language disorders, was associated with nonword repetition (p < .001), phonetic spelling (p = .002) and the reading and spelling composite score (p < .001). Gene-set analyses of candidate dyslexia and speech/language disorder genes were not significant. These findings contribute to the assessment of genetic associations in reading and language disorders, crucial for understanding their etiology and informing intervention strategies, and validate the approach of using unselected adult samples for gene discovery in language and reading.

    Additional information

    Supplementary materials
  • Dow, D. J., Huxley-Jones, J., Hall, J. M., Francks, C., Maycox, P. R., Kew, J. N., Gloger, I. S., Mehta, N. A., Kelly, F. M., Muglia, P., Breen, G., Jugurnauth, S., Pederoso, I., St.Clair, D., Rujescu, D., & Barnes, M. R. (2011). ADAMTSL3 as a candidate gene for schizophrenia: Gene sequencing and ultra-high density association analysis by imputation. Schizophrenia Research, 127(1-3), 28-34. doi:10.1016/j.schres.2010.12.009.

    Abstract

    We previously reported an association with a putative functional variant in the ADAMTSL3 gene, just below genome-wide significance in a genome-wide association study of schizophrenia. As variants impacting the function of ADAMTSL3 (a disintegrin-like and metalloprotease domain with thrombospondin type I motifs-like-3) could illuminate a novel disease mechanism and a potentially specific target, we have used complementary approaches to further evaluate the association. We imputed genotypes and performed high density association analysis using data from the HapMap and 1000 genomes projects. To review all variants that could potentially cause the association, and to identify additional possible pathogenic rare variants, we sequenced ADAMTSL3 in 92 schizophrenics. A total of 71 ADAMTSL3 variants were identified by sequencing, many were also seen in the 1000 genomes data, but 26 were novel. None of the variants identified by re-sequencing was in strong linkage disequilibrium (LD) with the associated markers. Imputation analysis refined association between ADAMTSL3 and schizophrenia, and highlighted additional common variants with similar levels of association. We evaluated the functional consequences of all variants identified by sequencing, or showing direct or imputed association. The strongest evidence for function remained with the originally associated variant, rs950169, suggesting that this variant may be causal of the association. Rare variants were also identified with possible functional impact. Our study confirms ADAMTSL3 as a candidate for further investigation in schizophrenia, using the variants identified here. The utility of imputation analysis is demonstrated, and we recommend wider use of this method to re-evaluate the existing canon of suggestive schizophrenia associations.
  • Dowell, C., Hajnal, A., Pouw, W., & Wagman, J. B. (2020). Visual and haptic perception of affordances of feelies. Perception, 49(9), 905-925. doi:10.1177/0301006620946532.

    Abstract

    Most objects have well-defined affordances. Investigating perception of affordances of objects that were not created for a specific purpose would provide insight into how affordances are perceived. In addition, comparison of perception of affordances for such objects across different exploratory modalities (visual vs. haptic) would offer a strong test of the lawfulness of information about affordances (i.e., the invariance of such information over transformation). Along these lines, “feelies”— objects created by Gibson with no obvious function and unlike any common object—could shed light on the processes underlying affordance perception. This study showed that when observers reported potential uses for feelies, modality significantly influenced what kind of affordances were perceived. Specifically, visual exploration resulted in more noun labels (e.g., “toy”) than haptic exploration which resulted in more verb labels (i.e., “throw”). These results suggested that overlapping, but distinct classes of action possibilities are perceivable using vision and haptics. Semantic network analyses revealed that visual exploration resulted in object-oriented responses focused on object identification, whereas haptic exploration resulted in action-oriented responses. Cluster analyses confirmed these results. Affordance labels produced in the visual condition were more consistent, used fewer descriptors, were less diverse, but more novel than in the haptic condition.
  • Drijvers, L., & Ozyurek, A. (2020). Non-native listeners benefit less from gestures and visible speech than native listeners during degraded speech comprehension. Language and Speech, 63(2), 209-220. doi:10.1177/0023830919831311.

    Abstract

    Native listeners benefit from both visible speech and iconic gestures to enhance degraded speech comprehension (Drijvers & Ozyürek, 2017). We tested how highly proficient non-native listeners benefit from these visual articulators compared to native listeners. We presented videos of an actress uttering a verb in clear, moderately, or severely degraded speech, while her lips were blurred, visible, or visible and accompanied by a gesture. Our results revealed that unlike native listeners, non-native listeners were less likely to benefit from the combined enhancement of visible speech and gestures, especially since the benefit from visible speech was minimal when the signal quality was not sufficient.
  • Dronkers, N. F., Wilkins, D. P., Van Valin Jr., R. D., Redfern, B. B., & Jaeger, J. J. (2004). Lesion analysis of the brain areas involved in language comprehension. Cognition, 92, 145-177. doi:10.1016/j.cognition.2003.11.002.

    Abstract

    The cortical regions of the brain traditionally associated with the comprehension of language are Wernicke's area and Broca's area. However, recent evidence suggests that other brain regions might also be involved in this complex process. This paper describes the opportunity to evaluate a large number of brain-injured patients to determine which lesioned brain areas might affect language comprehension. Sixty-four chronic left hemisphere stroke patients were evaluated on 11 subtests of the Curtiss–Yamada Comprehensive Language Evaluation – Receptive (CYCLE-R; Curtiss, S., & Yamada, J. (1988). Curtiss–Yamada Comprehensive Language Evaluation. Unpublished test, UCLA). Eight right hemisphere stroke patients and 15 neurologically normal older controls also participated. Patients were required to select a single line drawing from an array of three or four choices that best depicted the content of an auditorily-presented sentence. Patients' lesions obtained from structural neuroimaging were reconstructed onto templates and entered into a voxel-based lesion-symptom mapping (VLSM; Bates, E., Wilson, S., Saygin, A. P., Dick, F., Sereno, M., Knight, R. T., & Dronkers, N. F. (2003). Voxel-based lesion-symptom mapping. Nature Neuroscience, 6(5), 448–450.) analysis along with the behavioral data. VLSM is a brain–behavior mapping technique that evaluates the relationships between areas of injury and behavioral performance in all patients on a voxel-by-voxel basis, similar to the analysis of functional neuroimaging data. Results indicated that lesions to five left hemisphere brain regions affected performance on the CYCLE-R, including the posterior middle temporal gyrus and underlying white matter, the anterior superior temporal gyrus, the superior temporal sulcus and angular gyrus, mid-frontal cortex in Brodmann's area 46, and Brodmann's area 47 of the inferior frontal gyrus. Lesions to Broca's and Wernicke's areas were not found to significantly alter language comprehension on this particular measure. Further analysis suggested that the middle temporal gyrus may be more important for comprehension at the word level, while the other regions may play a greater role at the level of the sentence. These results are consistent with those seen in recent functional neuroimaging studies and offer complementary data in the effort to understand the brain areas underlying language comprehension.
  • Drude, S. (2011). Awetí in relation with Kamayurá: The two Tupian languages of the Upper Xingu. In B. Franchetto (Ed.), Alto Xingu. Uma sociedade multilíngüe (pp. 155-192). Rio de Janeiro: Museu do Indio - FUNAI.

    Abstract

    The article analyzes the relation between Aweti and Kamayurá on different levels. Both languages belong to different branches of the subfamily “Maweti-Guarani” within the large Tupi ‘stock’. Both peoples have arrived rather late to the complex Upper Xinguan society, but probably independently and from different directions. Both resulted from mergers of different groups and suffered a dramatic demographic decline in the first half of last century. There is no concrete evidence that these groups spoke varieties of more than 2 different languages (Pre-Aweti and Pre-Kamayurá). Today, many Aweti are at least passive bilinguals with Kamayurá, their most important allies, but the opposite does not hold. The article also discusses the relations between the languages on the main structural levels. In phonology, the phoneme inventories are compared and the sound changes are listed that occurred from the hypothetical proto-language “Proto-Maweti-Guarani” to Aweti, on the one hand, and to Proto-Tupi-Guarani and further to Kamayurá, on the other. In morpho-syntax, the article offers a comparison of the person systems and of affixes in general, treating in particular the so-called ‘relational prefixes’, which do not exist in Aweti. The most important syntactic shared properties are also listed. There seem to be very little mutual lexical borrowing. In the appendix, a list of more than 60 cognates with reconstructed proto-forms is given. Key-words: Aweti; Kamayurá; Sociolinguistics; History; Phonology.
  • Drude, S., Trilsbeek, P., Sloetjes, H., & Broeder, D. (2014). Best practices in the creation, archiving and dissemination of speech corpora at the Language Archive. In S. Ruhi, M. Haugh, T. Schmidt, & K. Wörner (Eds.), Best Practices for Spoken Corpora in Linguistic Research (pp. 183-207). Newcastle upon Tyne: Cambridge Scholars Publishing.
  • Drude, S. (2011). Comparando línguas alto‐xinguanas: Metodologia e bases de dados comparativos. In B. Franchetto (Ed.), Alto Xingu. Uma sociedade multilíngüe (pp. 39-56). Rio de Janeiro: Museu do Indio - FUNAI.

    Abstract

    A key for understanding the Upper Xingu system is the comparison of the different languages which are part of that multilingual society. This article discusses the notion ‘comparing languages’ and delineates a research program in accordance to which a fruitful comparison can be done on four levels: 1) structural (phonological and morphosyntactic), 2) lexical (semantic structure of the lexica and individual lexical items), 3) discourse (figures of speech and thought), 4) content (in particular, narratives). The language data of the project gathered so far (focusing on level 2 and 4) is described in detail: 10 comparative word lists from different semantic domains, and a core of 5 analogous texts of different genera. Finally, some general considerations are offered about how to analyze both similarities and divergence found among the compared material.
  • Drude, S. (2011). 'Derivational verbs' and other multi-verb constructions in Aweti and Tupi-Guarani. In A. Y. Aikhenvald, & P. C. Muysken (Eds.), Multi-verb constructions: A view from the Americas (pp. 213-254). Leiden: Brill.
  • Drude, S. (2002). Fala masculina e feminina em Awetí. In A. D. Rodrigues, & A. S. A. C. Cabral (Eds.), Línguas indígenas Brasileiras: Fonologia, gramática e história. (Atas do I Encontro Internacional do Grupo de Trabalho sobre Línguas Indígenas da ANPOLL). vol. 1 (pp. 177-190). Belém: EDUFPA.
  • Drude, S. (2011). Nominalization and subordination in Awetí. Amerindia, 35, 189-218.

    Abstract

    This paper describes the different kinds of nominalizations and the main forms used in subordination in Awetí, a Tupian language spoken by ca. 150 people in central Bra-zil in the Upper Xingu area. Awetí does not belong to, but is arguably the closest rela-tive of the well-known Tupí-Guaraní subfamily, the largest branch of the Tupí stock. In our analysis, subordination in Awetí is achieved by means of forms which may have developed from nominalizations, but which are synchronously possibly best classified as verbal moods, belonging into the verbal paradigm. On the other hand, nouns (and in particular nouns derived from verbs) often appear as predicates, especially in equality and cleft sentences.
  • Drude, S. (2014). Reduplication as a tool for morphological and phonological analysis in Awetí. In G. G. Gómez, & H. Van der Voort (Eds.), Reduplication in Indigenous languages of South America (pp. 185-216). Leiden: Brill.
  • Drude, S., Broeder, D., & Trilsbeek, P. (2014). The Language Archive and its solutions for sustainable endangered languages corpora. Book 2.0, 4, 5-20. doi:10.1386/btwo.4.1-2.5_1.

    Abstract

    Since the late 1990s, the technical group at the Max-Planck-Institute for Psycholinguistics has worked on solutions for important challenges in building sustainable data archives, in particular, how to guarantee long-time-availability of digital research data for future research. The support for the well-known DOBES (Documentation of Endangered Languages) programme has greatly inspired and advanced this work, and lead to the ongoing development of a whole suite of tools for annotating, cataloguing and archiving multi-media data. At the core of the LAT (Language Archiving Technology) tools is the IMDI metadata schema, now being integrated into a larger network of digital resources in the European CLARIN project. The multi-media annotator ELAN (with its web-based cousin ANNEX) is now well known not only among documentary linguists. We aim at presenting an overview of the solutions, both achieved and in development, for creating and exploiting sustainable digital data, in particular in the area of documenting languages and cultures, and their interfaces with related other developments
  • Drude, S. (2011). Word accent and its manifestation in Awetí. Amerindia, 35, 7-40.

    Abstract

    This paper describes the distribution and phonetic properties of accentuation of word forms in Awetí, a Tupian language spoken by ca. 150 people in central Brazil in the Upper Xingu area. Awetí does not belong to, but is arguably the closest relative of the better known Tupí-Guaraní subfamily, the largest branch of the Tupí stock. After a short overview over the word classes and general phonotactics of Awetí (sec-tion 2), we briefly discuss the notion ‘word accent’ and show that, in Awetí, it is generally located on the last syllable of the stem in morphologically simple forms (section 3). We then discuss regular and isolated exceptions to this rule (section 4). In section 5, we describe the distribution of the word accent when inflectional or deriva-tional suffixes are present – usually, the word accent of the word form with suffixes continues to be on the last syllable of the stem. After this descriptive part, we present a preliminary study of the acoustic-phonetic details of the manifestation of the word accent, observing word forms in isolation (section 6) and in different syntactic con-texts (section 7). The results are briefly summarized in the conclusion (section 8)
  • Dufau, S., Duñabeitia, J. A., Moret-Tatay, C., McGonigal, A., Peeters, D., Alario, F.-X., Balota, D. A., Brysbaert, M., Carreiras, M., Ferrand, L., Ktori, M., Perea, M., Rastle, K., Sasburg, O., Yap, M. J., Ziegler, J. C., & Grainger, J. (2011). Smart phone, smart science: How the use of smartphones can revolutionize research in cognitive science. PLoS One, 6(9), e24974. doi:10.1371/journal.pone.0024974.

    Abstract

    Investigating human cognitive faculties such as language, attention, and memory most often relies on testing small and homogeneous groups of volunteers coming to research facilities where they are asked to participate in behavioral experiments. We show that this limitation and sampling bias can be overcome by using smartphone technology to collect data in cognitive science experiments from thousands of subjects from all over the world. This mass coordinated use of smartphones creates a novel and powerful scientific ‘‘instrument’’ that yields the data necessary to test universal theories of cognition. This increase in power represents a potential revolution in cognitive science
  • Dunn, M., Reesink, G., & Terrill, A. (2002). The East Papuan languages: A preliminary typological appraisal. Oceanic Linguistics, 41(1), 28-62.

    Abstract

    This paper examines the Papuan languages of Island Melanesia, with a view to considering their typological similarities and differences. The East Papuan languages are thought to be the descendants of the languages spoken by the original inhabitants of Island Melanesia, who arrived in the area up to 50,000 years ago. The Oceanic Austronesian languages are thought to have come into the area with the Lapita peoples 3,500 years ago. With this historical backdrop in view, our paper seeks to investigate the linguistic relationships between the scattered Papuan languages of Island Melanesia. To do this, we survey various structural features, including syntactic patterns such as constituent order in clauses and noun phrases and other features of clause structure, paradigmatic structures of pronouns, and the structure of verbal morphology. In particular, we seek to discern similarities between the languages that might call for closer investigation, with a view to establishing genetic relatedness between some or all of the languages. In addition, in examining structural relationships between languages, we aim to discover whether it is possible to distinguish between original Papuan elements and diffused Austronesian elements of these languages. As this is a vast task, our paper aims merely to lay the groundwork for investigation into these and related questions.

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