Publications

Displaying 201 - 300 of 523
  • Kempen, G., & Harbusch, K. (2003). A corpus study into word order variation in German subordinate clauses: Animacy affects linearization independently of function assignment. In Proceedings of AMLaP 2003 (pp. 153-154). Glasgow: Glasgow University.
  • Kempen, G. (1991). Conjunction reduction and gapping in clause-level coordination: An inheritance-based approach. Computational Intelligence, 7, 357-360. doi:10.1111/j.1467-8640.1991.tb00406.x.
  • Kempen, G. (1995). De mythe van het woordbeeld: Spellingherziening taalpsychologisch doorgelicht. Onze Taal, 64(11), 275-277.
  • Kempen, G. (1988). De netwerker: Spin in het web of rat in een doolhof? In SURF in theorie en praktijk: Van personal tot supercomputer (pp. 59-61). Amsterdam: Elsevier Science Publishers.
  • Kempen, G. (1975). De taalgebruiker in de mens: Schets van zijn bouw en funktie, toepassingen op moedertaal en vreemde taal verwerving. Forum der Letteren, 16, 132-158.
  • Kempen, G. (1995). Drinken eten mij Nim. Intermediair, 31(19), 41-45.
  • Kempen, G. (1998). Comparing and explaining the trajectories of first and second language acquisition: In search of the right mix of psychological and linguistic factors [Commentory]. Bilingualism: Language and Cognition, 1, 29-30. doi:10.1017/S1366728998000066.

    Abstract

    When you compare the behavior of two different age groups which are trying to master the same sensori-motor or cognitive skill, you are likely to discover varying learning routes: different stages, different intervals between stages, or even different orderings of stages. Such heterogeneous learning trajectories may be caused by at least six different types of factors: (1) Initial state: the kinds and levels of skills the learners have available at the onset of the learning episode. (2) Learning mechanisms: rule-based, inductive, connectionist, parameter setting, and so on. (3) Input and feedback characteristics: learning stimuli, information about success and failure. (4) Information processing mechanisms: capacity limitations, attentional biases, response preferences. (5) Energetic variables: motivation, emotional reactions. (6) Final state: the fine-structure of kinds and levels of subskills at the end of the learning episode. This applies to language acquisition as well. First and second language learners probably differ on all six factors. Nevertheless, the debate between advocates and opponents of the Fundamental Difference Hypothesis concerning L1 and L2 acquisition have looked almost exclusively at the first two factors. Those who believe that L1 learners have access to Universal Grammar whereas L2 learners rely on language processing strategies, postulate different learning mechanisms (UG parameter setting in L1, more general inductive strategies in L2 learning). Pienemann opposes this view and, based on his Processability Theory, argues that L1 and L2 learners start out from different initial states: they come to the grammar learning task with different structural hypotheses (SOV versus SVO as basic word order of German).
  • Kempen, G. (1995). 'Hier spreekt men Nederlands'. EMNET: Nieuwsbrief Elektronische Media, 22, 1.
  • Kempen, G., & Harbusch, K. (1998). A 'tree adjoining' grammar without adjoining: The case of scrambling in German. In Fourth International Workshop on Tree Adjoining Grammars and Related Frameworks (TAG+4).
  • Kempen, G., & Harbusch, K. (2003). An artificial opposition between grammaticality and frequency: Comment on Bornkessel, Schlesewsky & Friederici (2002). Cognition, 90(2), 205-210 [Rectification on p. 215]. doi:10.1016/S0010-0277(03)00145-8.

    Abstract

    In a recent Cognition paper (Cognition 85 (2002) B21), Bornkessel, Schlesewsky, and Friederici report ERP data that they claim “show that online processing difficulties induced by word order variations in German cannot be attributed to the relative infrequency of the constructions in question, but rather appear to reflect the application of grammatical principles during parsing” (p. B21). In this commentary we demonstrate that the posited contrast between grammatical principles and construction (in)frequency as sources of parsing problems is artificial because it is based on factually incorrect assumptions about the grammar of German and on inaccurate corpus frequency data concerning the German constructions involved.
  • Kempen, G. (1999). Fiets en (centri)fuge. Onze Taal, 68, 88.
  • Kempen, G. (1995). IJ of Y? Onze Taal, 64(9), 205-206.
  • Kempen, G., & Olsthoorn, N. (2005). Non-parallelism of grammatical encoding and decoding due to shared working memory [Abstract]. In AMLaP-2005 11th Annual Conference on Architectures and Mechanisms for Language Processing September 5-7, 2005 Ghent, Belgium (pp. 24).
  • Kempen, G. (1995). Processing discontinuous lexical items: A reply to Frazier. Cognition, 55, 219-221. doi:10.1016/0010-0277(94)00657-7.

    Abstract

    Comments on a study by Frazier and others on Dutch-language lexical processing. Claims that the control condition in the experiment was inadequate and that an assumption made by Frazier about closed class verbal items is inaccurate, and proposes an alternative account of a subset of the data from the experiment
  • Kempen, G. (1995). Processing separable complex verbs in Dutch: Comments on Frazier, Flores d'Arcais, and Coolen (1993). Cognition, 54, 353-356. doi:10.1016/0010-0277(94)00649-6.

    Abstract

    Raises objections to L. Frazier et al's (see record 1994-32229-001) report of an experimental study intended to test Schreuder's (1990) Morphological Integration (MI) model concerning the processing of separable and inseparable verbs and shows that the logic of the experiment is flawed. The problem is rooted in the notion of a separable complex verb. The conclusion is drawn that Frazier et al's experimental data cannot be taken as evidence for the theoretical propositions they develop about the MI model.
  • Kempen, G. (1985). Psychologie 2000. Toegepaste psychologie in de informatiemaatschappij. Computers in de psychologie, 13-21.
  • Kempen, G. (1988). Preface. Acta Psychologica, 69(3), 205-206. doi:10.1016/0001-6918(88)90032-7.
  • Kempen, G. (1975). Theoretiseren en experimenteren in de cognitieve psychologie. Gedrag: Tijdschrift voor Psychologie, 6, 341-347.
  • Kempen, G. (1995). Van leescultuur en beeldcultuur naar internetcultuur. De Psycholoog, 30, 315-319.
  • Kemps, R. J. J. K., Wurm, L. H., Ernestus, M., Schreuder, R., & Baayen, R. H. (2005). Prosodic cues for morphological complexity in Dutch and English. Language and Cognitive Processes, 20(1/2), 43-73. doi:10.1080/01690960444000223.

    Abstract

    Previous work has shown that Dutch listeners use prosodic information in the speech signal to optimise morphological processing: Listeners are sensitive to prosodic differences between a noun stem realised in isolation and a noun stem realised as part of a plural form (in which the stem is followed by an unstressed syllable). The present study, employing a lexical decision task, provides an additional demonstration of listeners' sensitivity to prosodic cues in the stem. This sensitivity is shown for two languages that differ in morphological productivity: Dutch and English. The degree of morphological productivity does not correlate with listeners' sensitivity to prosodic cues in the stem, but it is reflected in differential sensitivities to the word-specific log odds ratio of encountering an unshortened stem (i.e., a stem in isolation) versus encountering a shortened stem (i.e., a stem followed by a suffix consisting of one or more unstressed syllables). In addition to being sensitive to the prosodic cues themselves, listeners are also sensitive to the probabilities of occurrence of these prosodic cues.
  • Kemps, R. J. J. K., Ernestus, M., Schreuder, R., & Baayen, R. H. (2005). Prosodic cues for morphological complexity: The case of Dutch plural nouns. Memory & Cognition, 33(3), 430-446.

    Abstract

    It has recently been shown that listeners use systematic differences in vowel length and intonation to resolve ambiguities between onset-matched simple words (Davis, Marslen-Wilson, & Gaskell, 2002; Salverda, Dahan, & McQueen, 2003). The present study shows that listeners also use prosodic information in the speech signal to optimize morphological processing. The precise acoustic realization of the stem provides crucial information to the listener about the morphological context in which the stem appears and attenuates the competition between stored inflectional variants. We argue that listeners are able to make use of prosodic information, even though the speech signal is highly variable within and between speakers, by virtue of the relative invariance of the duration of the onset. This provides listeners with a baseline against which the durational cues in a vowel and a coda can be evaluated. Furthermore, our experiments provide evidence for item-specific prosodic effects.
  • Keune, K., Ernestus, M., Van Hout, R., & Baayen, R. H. (2005). Variation in Dutch: From written "mogelijk" to spoken "mok". Corpus Linguistics and Linguistic Theory, 1(2), 183-223. doi:10.1515/cllt.2005.1.2.183.

    Abstract

    In Dutch, high-frequency words with the suffix -lijk are often highly reduced in spontaneous unscripted speech. This study addressed socio-geographic variation in the reduction of such words against the backdrop of the variation in their use in written and spoken Dutch. Multivariate analyses of the frequencies with which the words were used in a factorially contrasted set of subcorpora revealed signi ficant variation involving the speaker's country, sex, and education level for spoken Dutch, and involving country and register for written Dutch. Acoustic analyses revealed that Dutch men reduced most often, while Flemish highly educated women reduced least. Two linguistic context effects emerged, one prosodic, and the other pertaining to the flow of information. Words in sentence final position showed less reduction, while words that were better predictable from the preceding word in the sentence(based on mutual information) tended to be reduced more often. The increased probability of reduction for forms that are more predictable in context, combined with the loss of the suffix in the more extremely reduced forms, suggests that highfrequency words in -lijk are undergoing a process of erosion that causes them to gravitate towards monomorphemic function words.
  • Kidd, E., & Bavin, E. L. (2005). Lexical and referential cues to sentence interpretation: An investigation of children's interpretations of ambiguous sentences. Journal of Child Language, 32(4), 855-876. doi:10.1017/S0305000905007051.

    Abstract

    This paper reports on an investigation of children's (aged 3;5–9;8) comprehension of sentences containing ambiguity of prepositional phrase (PP) attachment. Results from a picture selection study (N=90) showed that children use verb semantics and preposition type to resolve the ambiguity, with older children also showing sensitivity to the definiteness of the object NP as a cue to interpretation. Study 2 investigated three- and five-year-old children's (N=47) ability to override an instrumental interpretation of ambiguous PPs in order to process attributes of the referential scene. The results showed that while five-year-olds are capable of incorporating aspects of the referential scene into their interpretations, three-year-olds are not as successful. Overall, the results suggest that children are attuned very early to the lexico-semantic co-occurrences that have been shown to aid ambiguity resolution in adults, but that more diffuse cues to interpretation are used only later in development
  • Kidd, E. (2003). Relative clause comprehension revisited: Commentary on Eisenberg (2002). Journal of Child Language, 30(3), 671-679. doi:10.1017/S0305000903005683.

    Abstract

    Eisenberg (2002) presents data from an experiment investigating three- and four-year-old children's comprehension of restrictive relative clauses (RC). From the results she argues, contrary to Hamburger & Crain (1982), that children do not have discourse knowledge of the felicity conditions of RCs before acquiring the syntax of relativization. This note evaluates this conclusion on the basis of the methodology used, and proposes that an account of syntactic development needs to be sensitive to the real-time processing requirements acquisition places on the learner.
  • Kita, S., & Ozyurek, A. (2003). What does cross-linguistic variation in semantic coordination of speech and gesture reveal? Evidence for an interface representation of spatial thinking and speaking. Journal of Memory and Language, 48(1), 16-32. doi:10.1016/S0749-596X(02)00505-3.

    Abstract

    Gestures that spontaneously accompany speech convey information coordinated with the concurrent speech. There has been considerable theoretical disagreement about the process by which this informational coordination is achieved. Some theories predict that the information encoded in gesture is not influenced by how information is verbally expressed. However, others predict that gestures encode only what is encoded in speech. This paper investigates this issue by comparing informational coordination between speech and gesture across different languages. Narratives in Turkish, Japanese, and English were elicited using an animated cartoon as the stimulus. It was found that gestures used to express the same motion events were influenced simultaneously by (1) how features of motion events were expressed in each language, and (2) spatial information in the stimulus that was never verbalized. From this, it is concluded that gestures are generated from spatio-motoric processes that interact on-line with the speech production process. Through the interaction, spatio-motoric information to be expressed is packaged into chunks that are verbalizable within a processing unit for speech formulation. In addition, we propose a model of speech and gesture production as one of a class of frameworks that are compatible with the data.
  • Kita, S., van Gijn, I., & van der Hulst, H. (1998). Movement phases in signs and co-speech gestures, and their transcription by human coders. In Gesture and Sign-Language in Human-Computer Interaction (Lecture Notes in Artificial Intelligence - LNCS Subseries, Vol. 1371) (pp. 23-35). Berlin, Germany: Springer-Verlag.

    Abstract

    The previous literature has suggested that the hand movement in co-speech gestures and signs consists of a series of phases with qualitatively different dynamic characteristics. In this paper, we propose a syntagmatic rule system for movement phases that applies to both co-speech gestures and signs. Descriptive criteria for the rule system were developed for the analysis video-recorded continuous production of signs and gesture. It involves segmenting a stream of body movement into phases and identifying different phase types. Two human coders used the criteria to analyze signs and cospeech gestures that are produced in natural discourse. It was found that the criteria yielded good inter-coder reliability. These criteria can be used for the technology of automatic recognition of signs and co-speech gestures in order to segment continuous production and identify the potentially meaningbearing phase.
  • Klein, W. (2005). Über den Nutzen naturwissenschaftlicher Denkmodelle für die Geisteswissenschaften. Debatte, 2, 45-50.
  • Klein, W. (2005). Vom Sprachvermögen zum Sprachlichen System. Zeitschrift für Literaturwissenschaft und Linguistik, 140, 8-39.
  • Klein, W. (2003). Wozu braucht man eigentlich Flexionsmorphologie? Zeitschrift für Literaturwissenschaft und Linguistik, 131, 23-54.
  • Klein, W. (2005). Wie ist eine exakte Wissenschaft von der Literatur möglich? Zeitschrift für Literaturwissenschaft und Linguistik, 137, 80-100.
  • Klein, W. (1995). A simplest analysis of the English tense-aspect system. In W. Riehle, & H. Keiper (Eds.), Proceedings of the Anglistentag 1994 (pp. 139-151). Tübingen: Niemeyer.
  • Klein, W. (1995). A time-relational analysis of Russian aspect. Language, 71(4), 669-695.
  • Klein, W. (1995). Das Vermächtnis der Geschichte, der Müll der Vergangenheit, oder: Wie wichtig ist zu wissen, was die Menschen früher getan oder geglaubt haben, für das, was wir jetzt tun oder glauben? Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 100, 77-100.
  • Klein, W. (1975). Eine Theorie der Wortstellungsveränderung: Einige kritische Bemerkungen zu Vennemanns Theorie der Sprachentwicklung. Linguistische Berichte, 37(75), 46-57.
  • Klein, W. (1985). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 15(59), 7-8.
  • Klein, W. (1975). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 5(18), 7-8.
  • Klein, W. (1988). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 18(69), 7-8.
  • Klein, W. (2005). Hoe is een exacte literatuurwetenschap mogelijk? Parmentier, 14(1), 48-65.
  • Klein, W. (1991). Geile Binsenbüschel, sehr intime Gespielen: Ein paar Anmerkungen über Arno Schmidt als Übersetzer. Zeitschrift für Literaturwissenschaft und Linguistik, 84, 124-129.
  • Klein, W. (1985). Gesprochene Sprache - geschriebene Sprache. Zeitschrift für Literaturwissenschaft und Linguistik, 59, 9-35.
  • Klein, W. (1995). Literaturwissenschaft, Linguistik, LiLi. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (100), 1-10.
  • Klein, W. (1991). Raumausdrücke. Linguistische Berichte, 132, 77-114.
  • Klein, W., & Von Stutterheim, C. (1991). Text structure and referential movement. Arbeitsberichte des Forschungsprogramms S&P: Sprache und Pragmatik, 22.
  • Klein, W. (1998). The contribution of second language acquisition research. Language Learning, 48, 527-550. doi:10.1111/0023-8333.00057.

    Abstract

    During the last 25 years, second language acquisition (SLA) research hasmade considerable progress, but is still far from proving a solid basis for foreign language teaching, or from a general theory of SLA. In addition, its status within the linguistic disciplines is still very low. I argue this has not much to do with low empirical or theoretical standards in the field—in this regard, SLA research is fully competitive—but with a particular perspective on the acquisition process: SLA researches learners' utterances as deviations from a certain target, instead of genuine manifestations of underlying language capacity; it analyses them in terms of what they are not rather than what they are. For some purposes such a "target deviation perspective" makes sense, but it will not help SLA researchers to substantially and independently contribute to a deeper understanding of the structure and function of the human language faculty. Therefore, these findings will remain of limited interest to other scientists until SLA researchers consider learner varieties a normal, in fact typical, manifestation of this unique human capacity.
  • Klein, W. (1988). Sprache und Krankheit: Ein paar Anmerkungen. Zeitschrift für Literaturwissenschaft und Linguistik, 69, 9-20.
  • Klein, W. (1991). Was kann sich die Übersetzungswissenschaft von der Linguistik erwarten? Zeitschrift für Literaturwissenschaft und Linguistik, 84, 104-123.
  • Klein, W. (1999). Wie sich das deutsche Perfekt zusammensetzt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (113), 52-85.
  • Klein, W. (1975). Zur Sprache ausländischer Arbeiter: Syntaktische Analysen und Aspekte des kommunikativen Verhaltens. Zeitschrift für Literaturwissenschaft und Linguistik, 18, 78-121.
  • Klein, W. (1998). Von der einfältigen Wißbegierde. Zeitschrift für Literaturwissenschaft und Linguistik, 112, 6-13.
  • Kooijman, V., Hagoort, P., & Cutler, A. (2005). Electrophysiological evidence for prelinguistic infants' word recognition in continuous speech. Cognitive Brain Research, 24(1), 109-116. doi:10.1016/j.cogbrainres.2004.12.009.

    Abstract

    Children begin to talk at about age one. The vocabulary they need to do so must be built on perceptual evidence and, indeed, infants begin to recognize spoken words long before they talk. Most of the utterances infants hear, however, are continuous, without pauses between words, so constructing a vocabulary requires them to decompose continuous speech in order to extract the individual words. Here, we present electrophysiological evidence that 10-month-old infants recognize two-syllable words they have previously heard only in isolation when these words are presented anew in continuous speech. Moreover, they only need roughly the first syllable of the word to begin doing this. Thus, prelinguistic infants command a highly efficient procedure for segmentation and recognition of spoken words in the absence of an existing vocabulary, allowing them to tackle effectively the problem of bootstrapping a lexicon out of the highly variable, continuous speech signals in their environment.
  • Köster, O., Hess, M. M., Schiller, N. O., & Künzel, H. J. (1998). The correlation between auditory speech sensitivity and speaker recognition ability. Forensic Linguistics: The international Journal of Speech, Language and the Law, 5, 22-32.

    Abstract

    In various applications of forensic phonetics the question arises as to how far aural-perceptual speaker recognition performance is reliable. Therefore, it is necessary to examine the relationship between speaker recognition results and human perception/production abilities like musicality or speech sensitivity. In this study, performance in a speaker recognition experiment and a speech sensitivity test are correlated. The results show a moderately significant positive correlation between the two tasks. Generally, performance in the speaker recognition task was better than in the speech sensitivity test. Professionals in speech and singing yielded a more homogeneous correlation than non-experts. Training in speech as well as choir-singing seems to have a positive effect on performance in speaker recognition. It may be concluded, firstly, that in cases where the reliability of voice line-up results or the credibility of a testimony have to be considered, the speech sensitivity test could be a useful indicator. Secondly, the speech sensitivity test might be integrated into the canon of possible procedures for the accreditation of forensic phoneticians. Both tests may also be used in combination.
  • Krämer, I. (1998). Children's interpretations of indefinite object noun phrases. Linguistics in the Netherlands, 1998, 163-174. doi:10.1075/avt.15.15kra.
  • Kuzla, C. (2003). Prosodically-conditioned variation in the realization of domain-final stops and voicing assimilation of domain-initial fricatives in German. In Proceedings of the 15th International Congress of Phonetic Sciences (ICPhS 2003) (pp. 2829-2832). Adelaide: Causal Productions.
  • Lai, C. S. L., Gerrelli, D., Monaco, A. P., Fisher, S. E., & Copp, A. J. (2003). FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain, 126(11), 2455-2462. doi:10.1093/brain/awg247.

    Abstract

    Disruption of FOXP2, a gene encoding a forkhead-domain transcription factor, causes a severe developmental disorder of verbal communication, involving profound articulation deficits, accompanied by linguistic and grammatical impairments. Investigation of the neural basis of this disorder has been limited previously to neuroimaging of affected children and adults. The discovery of the gene responsible, FOXP2, offers a unique opportunity to explore the relevant neural mechanisms from a molecular perspective. In the present study, we have determined the detailed spatial and temporal expression pattern of FOXP2 mRNA in the developing brain of mouse and human. We find expression in several structures including the cortical plate, basal ganglia, thalamus, inferior olives and cerebellum. These data support a role for FOXP2 in the development of corticostriatal and olivocerebellar circuits involved in motor control. We find intriguing concordance between regions of early expression and later sites of pathology suggested by neuroimaging. Moreover, the homologous pattern of FOXP2/Foxp2 expression in human and mouse argues for a role for this gene in development of motor-related circuits throughout mammalian species. Overall, this study provides support for the hypothesis that impairments in sequencing of movement and procedural learning might be central to the FOXP2-related speech and language disorder.
  • Lai, V. T. (2005). Language experience influences the conceptualization of TIME metaphor. In Proceedings of the II Conference on Metaphor in Language and Thought, Rio de Janeiro, Brazil, August 17-20, 2005.

    Abstract

    This paper examines the language-specific aspect of the TIME PASSING IS MOTION metaphor and suggests that the temporal construal of time can be influenced by a person's second language. Ahrens and Huang (2002) have analyzed the source domain of MOTION for the TIME metaphor into two special cases. In the special case one, TIME PASSING is an object that moves towards an ego. For example, qimuokao kuai dao le "the final exam is approaching." In the special case two, TIME PASSING is a point (that a plural ego is attached to) that moves across a landscape. For example, women kuai dao qimuokao le "we are approaching the final exam." In addition, in English, the ego in the special case one faces the future while in Chinese, the ego faces the past. The current experiment hypothesizes that English influences the choice of the orientation of the ego in native Chinese speakers who speak English as the second language. 54 subjects are asked to switch the clock time one hour forward. Results show that native Chinese speakers living in the Chinese speaking country tend to move the clock one hour forward to the past (92%) while native Chinese speakers living in an English speaking country are less likely to do so (60%). This implies that the experience of English influences the conceptualization of time in Mandarin Chinese.
  • De Lange, F. P., Hagoort, P., & Toni, I. (2003). Differential fronto-parietal contributions to visual and motor imagery. NeuroImage, 19(2), e2094-e2095.

    Abstract

    Mental imagery is a cognitive process crucial to human reasoning. Numerous studies have characterized specific
    instances of this cognitive ability, as evoked by visual imagery (VI) or motor imagery (MI) tasks. However, it
    remains unclear which neural resources are shared between VI and MI, and which are exclusively related to MI.
    To address this issue, we have used fMRI to measure human brain activity during performance of VI and MI
    tasks. Crucially, we have modulated the imagery process by manipulating the degree of mental rotation necessary
    to solve the tasks. We focused our analysis on changes in neural signal as a function of the degree of mental
    rotation in each task.
  • De Lange, F. P., Kalkman, J. S., Bleijenberg, G., Hagoort, P., Van der Meer, J. W. M., & Toni, I. (2005). Gray matter volume reduction in the chronic fatigue syndrome. NeuroImage, 26, 777-781. doi:10.1016/j.neuroimage.2005.02.037.

    Abstract

    The chronic fatigue syndrome (CFS) is a disabling disorder of unknown etiology. The symptomatology of CFS (central fatigue, impaired concentration, attention and memory) suggests that this disorder could be related to alterations at the level of the central nervous system. In this study, we have used an automated and unbiased morphometric technique to test whether CFS patients display structural cerebral abnormalities. We mapped structural cerebral morphology and volume in two cohorts of CFS patients (in total 28 patients) and healthy controls (in total 28 controls) from high-resolution structural magnetic resonance images, using voxel-based morphometry. Additionally, we recorded physical activity levels to explore the relation between severity of CFS symptoms and cerebral abnormalities. We observed significant reductions in global gray matter volume in both cohorts of CFS patients, as compared to matched control participants. Moreover, the decline in gray matter volume was linked to the reduction in physical activity, a core aspect of CFS. These findings suggest that the central nervous system plays a key role in the pathophysiology of CFS and point to a new objective and quantitative tool for clinical diagnosis of this disabling disorder.
  • De Lange, F. P., Hagoort, P., & Toni, I. (2005). Neural topography and content of movement representations. Journal of Cognitive Neuroscience, 17(1), 97-112. doi:10.1162/0898929052880039.

    Abstract

    We have used implicit motor imagery to investigate the neural correlates of motor planning independently from actual movements. Subjects were presented with drawings of left or right hands and asked to judge the hand laterality, regardless of the stimulus rotation from its upright orientation. We paired this task with a visual imagery control task, in which subjects were presented with typographical characters and asked to report whether they saw a canonical letter or its mirror image, regardless of its rotation. We measured neurovascular activity with fast event-related fMRI, distinguishing responses parametrically related to motor imagery from responses evoked by visual imagery and other task-related phenomena. By quantifying behavioral and neurovascular correlates of imagery on a trial-by-trial basis, we could discriminate between stimulusrelated, mental rotation-related, and response-related neural activity. We found that specific portions of the posterior parietal and precentral cortex increased their activity as a function of mental rotation only during the motor imagery task. Within these regions, the parietal cortex was visually responsive, whereas the dorsal precentral cortex was not. Response- but not rotation-related activity was found around the left central sulcus (putative primary motor cortex) during both imagery tasks. Our study provides novel evidence on the topography and content of movement representations in the human brain. During intended action, the posterior parietal cortex combines somatosensory and visuomotor information, whereas the dorsal premotor cortex generates the actual motor plan, and the primary motor cortex deals with movement execution. We discuss the relevance of these results in the context of current models of action planning.
  • Lausberg, H., Cruz, R. F., Kita, S., Zaidel, E., & Ptito, A. (2003). Pantomime to visual presentation of objects: Left hand dyspraxia in patients with complete callosotomy. Brain, 126(2), 343-360. doi:10.1093/brain/awg042.

    Abstract

    Investigations of left hand praxis in imitation and object use in patients with callosal disconnection have yielded divergent results, inducing a debate between two theoretical positions. Whereas Liepmann suggested that the left hemisphere is motor dominant, others maintain that both hemispheres have equal motor competences and propose that left hand apraxia in patients with callosal disconnection is secondary to left hemispheric specialization for language or other task modalities. The present study aims to gain further insight into the motor competence of the right hemisphere by investigating pantomime of object use in split-brain patients. Three patients with complete callosotomy and, as control groups, five patients with partial callosotomy and nine healthy subjects were examined for their ability to pantomime object use to visual object presentation and demonstrate object manipulation. In each condition, 11 objects were presented to the subjects who pantomimed or demonstrated the object use with either hand. In addition, six object pairs were presented to test bimanual coordination. Two independent raters evaluated the videotaped movement demonstrations. While object use demonstrations were perfect in all three groups, the split-brain patients displayed apraxic errors only with their left hands in the pantomime condition. The movement analysis of concept and execution errors included the examination of ipsilateral versus contralateral motor control. As the right hand/left hemisphere performances demonstrated retrieval of the correct movement concepts, concept errors by the left hand were taken as evidence for right hemisphere control. Several types of execution errors reflected a lack of distal motor control indicating the use of ipsilateral pathways. While one split-brain patient controlled his left hand predominantly by ipsilateral pathways in the pantomime condition, the error profile in the other two split-brain patients suggested that the right hemisphere controlled their left hands. In the object use condition, in all three split-brain patients fine-graded distal movements in the left hand indicated right hemispheric control. Our data show left hand apraxia in split-brain patients is not limited to verbal commands, but also occurs in pantomime to visual presentation of objects. As the demonstration with object in hand was unimpaired in either hand, both hemispheres must contain movement concepts for object use. However, the disconnected right hemisphere is impaired in retrieving the movement concept in response to visual object presentation, presumably because of a deficit in associating perceptual object representation with the movement concepts.
  • Lausberg, H., Kita, S., Zaidel, E., & Ptito, A. (2003). Split-brain patients neglect left personal space during right-handed gestures. Neuropsychologia, 41(10), 1317-1329. doi:10.1016/S0028-3932(03)00047-2.

    Abstract

    Since some patients with right hemisphere damage or with spontaneous callosal disconnection neglect the left half of space, it has been suggested that the left cerebral hemisphere predominantly attends to the right half of space. However, clinical investigations of patients having undergone surgical callosal section have not shown neglect when the hemispheres are tested separately. These observations question the validity of theoretical models that propose a left hemispheric specialisation for attending to the right half of space. The present study aims to investigate neglect and the use of space by either hand in gestural demonstrations in three split-brain patients as compared to five patients with partial callosotomy and 11 healthy subjects. Subjects were asked to demonstrate with precise gestures and without speaking the content of animated scenes with two moving objects. The results show that in the absence of primary perceptual or representational neglect, split-brain patients neglect left personal space in right-handed gestural demonstrations. Since this neglect of left personal space cannot be explained by directional or spatial akinesia, it is suggested that it originates at the conceptual level, where the spatial coordinates for right-hand gestures are planned. The present findings are at odds with the position that the separate left hemisphere possesses adequate mechanisms for acting in both halves of space and neglect results from right hemisphere suppression of this potential. Rather, the results provide support for theoretical models that consider the left hemisphere as specialised for processing the right half of space during the execution of descriptive gestures.
  • Lausberg, H., & Kita, S. (2003). The content of the message influences the hand choice in co-speech gestures and in gesturing without speaking. Brain and Language, 86(1), 57-69. doi:10.1016/S0093-934X(02)00534-5.

    Abstract

    The present study investigates the hand choice in iconic gestures that accompany speech. In 10 right-handed subjects gestures were elicited by verbal narration and by silent gestural demonstrations of animations with two moving objects. In both conditions, the left-hand was used as often as the right-hand to display iconic gestures. The choice of the right- or left-hands was determined by semantic aspects of the message. The influence of hemispheric language lateralization on the hand choice in co-speech gestures appeared to be minor. Instead, speaking seemed to induce a sequential organization of the iconic gestures.
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (1999). A developmental grammar for syllable structure in the production of child language. Brain and Language, 68, 291-299.

    Abstract

    The order of acquisition of Dutch syllable types by first language learners is analyzed as following from an initial ranking and subsequent rerankings of constraints in an optimality theoretic grammar. Initially, structural constraints are all ranked above faithfulness constraints, leading to core syllable (CV) productions only. Subsequently, faithfulness gradually rises to the highest position in the ranking, allowing more and more marked syllable types to appear in production. Local conjunctions of Structural constraints allow for a more detailed analysis.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). A theory of lexical access in speech production. Behavioral and Brain Sciences, 22, 1-38. doi:10.1017/S0140525X99001776.

    Abstract

    Preparing words in speech production is normally a fast and accurate process. We generate them two or three per second in fluent conversation; and overtly naming a clear picture of an object can easily be initiated within 600 msec after picture onset. The underlying process, however, is exceedingly complex. The theory reviewed in this target article analyzes this process as staged and feedforward. After a first stage of conceptual preparation, word generation proceeds through lexical selection, morphological and phonological encoding, phonetic encoding, and articulation itself. In addition, the speaker exerts some degree of output control, by monitoring of self-produced internal and overt speech. The core of the theory, ranging from lexical selection to the initiation of phonetic encoding, is captured in a computational model, called WEAVER + +. Both the theory and the computational model have been developed in interaction with reaction time experiments, particularly in picture naming or related word production paradigms, with the aim of accounting. for the real-time processing in normal word production. A comprehensive review of theory, model, and experiments is presented. The model can handle some of the main observations in the domain of speech errors (the major empirical domain for most other theories of lexical access), and the theory opens new ways of approaching the cerebral organization of speech production by way of high-temporal-resolution imaging.
  • Levelt, W. J. M. (1991). Die konnektionistische Mode. Sprache und Kognition, 10(2), 61-72.
  • Levelt, W. J. M., Praamstra, P., Meyer, A. S., Helenius, P., & Salmelin, R. (1998). An MEG study of picture naming. Journal of Cognitive Neuroscience, 10(5), 553-567. doi:10.1162/089892998562960.

    Abstract

    The purpose of this study was to relate a psycholinguistic processing model of picture naming to the dynamics of cortical activation during picture naming. The activation was recorded from eight Dutch subjects with a whole-head neuromagnetometer. The processing model, based on extensive naming latency studies, is a stage model. In preparing a picture's name, the speaker performs a chain of specific operations. They are, in this order, computing the visual percept, activating an appropriate lexical concept, selecting the target word from the mental lexicon, phonological encoding, phonetic encoding, and initiation of articulation. The time windows for each of these operations are reasonably well known and could be related to the peak activity of dipole sources in the individual magnetic response patterns. The analyses showed a clear progression over these time windows from early occipital activation, via parietal and temporal to frontal activation. The major specific findings were that (1) a region in the left posterior temporal lobe, agreeing with the location of Wernicke's area, showed prominent activation starting about 200 msec after picture onset and peaking at about 350 msec, (i.e., within the stage of phonological encoding), and (2) a consistent activation was found in the right parietal cortex, peaking at about 230 msec after picture onset, thus preceding and partly overlapping with the left temporal response. An interpretation in terms of the management of visual attention is proposed.
  • Levelt, W. J. M. (2005). Habitual perspective. In Proceedings of the 27th Annual Meeting of the Cognitive Science Society (CogSci 2005).
  • Levelt, C. C., Fikkert, P., & Schiller, N. O. (2003). Metrical priming in speech production. In Proceedings of the 15th International Congress of Phonetic Sciences (ICPhS 2003) (pp. 2481-2485). Adelaide: Causal Productions.

    Abstract

    In this paper we report on four experiments in which we attempted to prime the stress position of Dutch bisyllabic target nouns. These nouns, picture names, had stress on either the first or the second syllable. Auditory prime words had either the same stress as the target or a different stress (e.g., WORtel – MOtor vs. koSTUUM – MOtor; capital letters indicate stressed syllables in prime – target pairs). Furthermore, half of the prime words were semantically related, the other half were unrelated. In none of the experiments a stress priming effect was found. This could mean that stress is not stored in the lexicon. An additional finding was that targets with initial stress had a faster response than targets with a final stress. We hypothesize that bisyllabic words with final stress take longer to be encoded because this stress pattern is irregular with respect to the lexical distribution of bisyllabic stress patterns, even though it can be regular in terms of the metrical stress rules of Dutch.
  • Levelt, W. J. M. (1999). Models of word production. Trends in Cognitive Sciences, 3, 223-232.

    Abstract

    Research on spoken word production has been approached from two angles. In one research tradition, the analysis of spontaneous or induced speech errors led to models that can account for speech error distributions. In another tradition, the measurement of picture naming latencies led to chronometric models accounting for distributions of reaction times in word production. Both kinds of models are, however, dealing with the same underlying processes: (1) the speaker’s selection of a word that is semantically and syntactically appropriate; (2) the retrieval of the word’s phonological properties; (3) the rapid syllabification of the word in context; and (4) the preparation of the corresponding articulatory gestures. Models of both traditions explain these processes in terms of activation spreading through a localist, symbolic network. By and large, they share the main levels of representation: conceptual/semantic, syntactic, phonological and phonetic. They differ in various details, such as the amount of cascading and feedback in the network. These research traditions have begun to merge in recent years, leading to highly constructive experimentation. Currently, they are like two similar knives honing each other. A single pair of scissors is in the making.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). Multiple perspectives on lexical access [authors' response ]. Behavioral and Brain Sciences, 22, 61-72. doi:10.1017/S0140525X99451775.
  • Levelt, W. J. M., & Plomp, R. (1962). Musical consonance and critical bandwidth. In Proceedings of the 4th International Congress Acoustics (pp. 55-55).
  • Levelt, W. J. M. (1995). Hoezo 'neuro'? Hoezo 'linguïstisch'? Intermediair, 31(46), 32-37.
  • Levelt, W. J. M. (1991). Lexical access in speech production: Stages versus cascading. In H. Peters, W. Hulstijn, & C. Starkweather (Eds.), Speech motor control and stuttering (pp. 3-10). Amsterdam: Excerpta Medica.
  • Levelt, W. J. M., & Schiller, N. O. (1998). Is the syllable frame stored? [Commentary on the BBS target article 'The frame/content theory of evolution of speech production' by Peter F. McNeilage]. Behavioral and Brain Sciences, 21, 520.

    Abstract

    This commentary discusses whether abstract metrical frames are stored. For stress-assigning languages (e.g., Dutch and English), which have a dominant stress pattern, metrical frames are stored only for words that deviate from the default stress pattern. The majority of the words in these languages are produced without retrieving any independent syllabic or metrical frame.
  • Levelt, W. J. M., Schriefers, H., Vorberg, D., Meyer, A. S., Pechmann, T., & Havinga, J. (1991). Normal and deviant lexical processing: Reply to Dell and O'Seaghdha. Psychological Review, 98(4), 615-618. doi:10.1037/0033-295X.98.4.615.

    Abstract

    In their comment, Dell and O'Seaghdha (1991) adduced any effect on phonological probes for semantic alternatives to the activation of these probes in the lexical network. We argue that that interpretation is false and, in addition, that the model still cannot account for our data. Furthermore, and different from Dell and O'seaghda, we adduce semantic rebound to the lemma level, where it is so substantial that it should have shown up in our data. Finally, we question the function of feedback in a lexical network (other than eliciting speech errors) and discuss Dell's (1988) notion of a unified production-comprehension system.
  • Levelt, W. J. M. (1988). Onder sociale wetenschappen. Mededelingen van de Afdeling Letterkunde, 51(2), 41-55.
  • Levelt, W. J. M. (1995). The ability to speak: From intentions to spoken words. European Review, 3(1), 13-23. doi:10.1017/S1062798700001290.

    Abstract

    In recent decades, psychologists have become increasingly interested in our ability to speak. This paper sketches the present theoretical perspective on this most complex skill of homo sapiens. The generation of fluent speech is based on the interaction of various processing components. These mechanisms are highly specialized, dedicated to performing specific subroutines, such as retrieving appropriate words, generating morpho-syntactic structure, computing the phonological target shape of syllables, words, phrases and whole utterances, and creating and executing articulatory programmes. As in any complex skill, there is a self-monitoring mechanism that checks the output. These component processes are targets of increasingly sophisticated experimental research, of which this paper presents a few salient examples.
  • Levelt, W. J. M., & Flores d'Arcais, G. B. (1975). Some psychologists' reactions to the Symposium of Dynamic Aspects of Speech Perception. In A. Cohen, & S. Nooteboom (Eds.), Structure and process in speech perception (pp. 345-351). Berlin: Springer.
  • Levelt, W. J. M., Richardson, G., & La Heij, W. (1985). Pointing and voicing in deictic expressions. Journal of Memory and Language, 24, 133-164. doi:10.1016/0749-596X(85)90021-X.

    Abstract

    The present paper studies how, in deictic expressions, the temporal interdependency of speech and gesture is realized in the course of motor planning and execution. Two theoretical positions were compared. On the “interactive” view the temporal parameters of speech and gesture are claimed to be the result of feedback between the two systems throughout the phases of motor planning and execution. The alternative “ballistic” view, however, predicts that the two systems are independent during the phase of motor execution, the temporal parameters having been preestablished in the planning phase. In four experiments subjects were requested to indicate which of an array of referent lights was momentarily illuminated. This was done by pointing to the light and/or by using a deictic expression (this/that light). The temporal and spatial course of the pointing movement was automatically registered by means of a Selspot opto-electronic system. By analyzing the moments of gesture initiation and apex, and relating them to the moments of speech onset, it was possible to show that, for deictic expressions, the ballistic view is very nearly correct.
  • Levelt, W. J. M. (1998). The genetic perspective in psycholinguistics, or: Where do spoken words come from? Journal of Psycholinguistic Research, 27(2), 167-180. doi:10.1023/A:1023245931630.

    Abstract

    The core issue in the 19-century sources of psycholinguistics was the question, "Where does language come from?'' This genetic perspective unified the study of the ontogenesis, the phylogenesis, the microgenesis, and to some extent the neurogenesis of language. This paper makes the point that this original perspective is still a valid and attractive one. It is exemplified by a discussion of the genesis of spoken words.
  • Levelt, W. J. M., Schriefer, H., Vorberg, D., Meyer, A. S., Pechmann, T., & Havinga, J. (1991). The time course of lexical access in speech production: A study of picture naming. Psychological Review, 98(1), 122-142. doi:10.1037/0033-295X.98.1.122.
  • Levinson, S. C., & Brown, P. (2003). Emmanuel Kant chez les Tenejapans: L'Anthropologie comme philosophie empirique [Translated by Claude Vandeloise for 'Langues et Cognition']. Langues et Cognition, 239-278.

    Abstract

    This is a translation of Levinson and Brown (1994).
  • Levinson, S. C., & Meira, S. (2003). 'Natural concepts' in the spatial topological domain - adpositional meanings in crosslinguistic perspective: An exercise in semantic typology. Language, 79(3), 485-516.

    Abstract

    Most approaches to spatial language have assumed that the simplest spatial notions are (after Piaget) topological and universal (containment, contiguity, proximity, support, represented as semantic primitives suchas IN, ON, UNDER, etc.). These concepts would be coded directly in language, above all in small closed classes suchas adpositions—thus providing a striking example of semantic categories as language-specific projections of universal conceptual notions. This idea, if correct, should have as a consequence that the semantic categories instantiated in spatial adpositions should be essentially uniform crosslinguistically. This article attempts to verify this possibility by comparing the semantics of spatial adpositions in nine unrelated languages, with the help of a standard elicitation procedure, thus producing a preliminary semantic typology of spatial adpositional systems. The differences between the languages turn out to be so significant as to be incompatible withstronger versions of the UNIVERSAL CONCEPTUAL CATEGORIES hypothesis. Rather, the language-specific spatial adposition meanings seem to emerge as compact subsets of an underlying semantic space, withcertain areas being statistical ATTRACTORS or FOCI. Moreover, a comparison of systems withdifferent degrees of complexity suggests the possibility of positing implicational hierarchies for spatial adpositions. But such hierarchies need to be treated as successive divisions of semantic space, as in recent treatments of basic color terms. This type of analysis appears to be a promising approachfor future work in semantic typology.
  • Levinson, S. C. (2005). [Comment on: Cultural constraints on grammar and cognition in Piraha by Daniel L. Everett]. Current Anthropology, 46, 637-638.
  • Levinson, S. C. (2005). Living with Manny's dangerous idea. Discourse Studies, 7(4-5), 431-453. doi:10.1177/1461445605054401.

    Abstract

    Daniel Dennett, in Darwin's Dangerous Idea, argues that natural selection is a universal acid that eats through other theories, because it can explain just about everything, even the structure of the mind. Emanuel (Manny) Schegloff (1987) in ‘Between Micro and Macro: Context and Other Connections’ opposes the importation of ‘macro’ (sociological/sociolinguistic) factors into the ‘micro’ (interaction analysis), suggesting that one might reverse the strategy instead. Like Darwin, he is coy about whether he just wants his own turf, but the idea opens up the possibility of interactional reductionism. I will argue against interactional reductionism on methodological grounds: Don't bite off more than you can chew! Instead I'll support the good old Durkheimian strategy of looking for intermediate variables between systems of different orders. I try and make the case with data from Rossel Island, Papua New Guinea.
  • Levinson, S. C. (2005). Languages: Europe puts it's money where its mouth is [Letter to the editor]. Nature, 438, 914-914. doi:doi:10.1038/438914c.
  • Levinson, S. C., & Senft, G. (1991). Forschungsgruppe für Kognitive Anthropologie - Eine neue Forschungsgruppe in der Max-Planck-Gesellschaft. Linguistische Berichte, 133, 244-246.
  • Levinson, S. C. (1999). Maxim. Journal of Linguistic Anthropology, 9, 144-147. doi:10.1525/jlin.1999.9.1-2.144.
  • Levinson, S. C., & Senft, G. (1991). Research group for cognitive anthropology - A new research group of the Max Planck Society. Cognitive Linguistics, 2, 311-312.
  • Levinson, S. C. (1998). Studying spatial conceptualization across cultures: Anthropology and cognitive science. Ethos, 26(1), 7-24. doi:10.1525/eth.1998.26.1.7.

    Abstract

    Philosophers, psychologists, and linguists have argued that spatial conception is pivotal to cognition in general, providing a general, egocentric, and universal framework for cognition as well as metaphors for conceptualizing many other domains. But in an aboriginal community in Northern Queensland, a system of cardinal directions informs not only language, but also memory for arbitrary spatial arrays and directions. This work suggests that fundamental cognitive parameters, like the system of coding spatial locations, can vary cross-culturally, in line with the language spoken by a community. This opens up the prospect of a fruitful dialogue between anthropology and the cognitive sciences on the complex interaction between cultural and universal factors in the constitution of mind.
  • Levinson, S. C. (1991). Pragmatic reduction of the Binding Conditions revisited. Journal of Linguistics, 27, 107-161. doi:10.1017/S0022226700012433.

    Abstract

    In an earlier article (Levinson, 1987b), I raised the possibility that a Gricean theory of implicature might provide a systematic partial reduction of the Binding Conditions; the briefest of outlines is given in Section 2.1 below but the argumentation will be found in the earlier article. In this article I want, first, to show how that account might be further justified and extended, but then to introduce a radical alternative. This alternative uses the same pragmatic framework, but gives an account better adjusted to some languages. Finally, I shall attempt to show that both accounts can be combined by taking a diachronic perspective. The attraction of the combined account is that, suddenly, many facts about long-range reflexives and their associated logophoricity fall into place.
  • Liszkowski, U. (2005). Human twelve-month-olds point cooperatively to share interest with and helpfully provide information for a communicative partner. Gesture, 5(1-2), 135-154. doi:10.1075/gest.5.1.11lis.

    Abstract

    This paper investigates infant pointing at 12 months. Three recent experimental studies from our lab are reported and contrasted with existing accounts on infant communicative and social-cognitive abilities. The new results show that infant pointing at 12 months already is a communicative act which involves the intentional transmission of information to share interest with, or provide information for other persons. It is argued that infant pointing is an inherently social and cooperative act which is used to share psychological relations between interlocutors and environment, repairs misunderstandings in proto-conversational turn-taking, and helps others by providing information. Infant pointing builds on an understanding of others as persons with attentional states and attitudes. Findings do not support lean accounts on early infant pointing which posit that it is initially non-communicative, does not serve the function of indicating, or is purely self-centered. It is suggested to investigate the emergence of reference and the motivation to jointly engage with others also before pointing has emerged.
  • Lundstrom, B. N., Petersson, K. M., Andersson, J., Johansson, M., Fransson, P., & Ingvar, M. (2003). Isolating the retrieval of imagined pictures during episodic memory: Activation of the left precuneus and left prefrontal cortex. Neuroimage, 20, 1934-1943. doi:10.1016/j.neuroimage.2003.07.017.

    Abstract

    The posterior medial parietal cortex and the left prefrontal cortex have both been implicated in the recollection of past episodes. In order to clarify their functional significance, we performed this functional magnetic resonance imaging study, which employed event-related source memory and item recognition retrieval of words paired with corresponding imagined or viewed pictures. Our results suggest that episodic source memory is related to a functional network including the posterior precuneus and the left lateral prefrontal cortex. This network is activated during explicit retrieval of imagined pictures and results from the retrieval of item-context associations. This suggests that previously imagined pictures provide a context with which encoded words can be more strongly associated.
  • Lundstrom, B. N., Ingvar, M., & Petersson, K. M. (2005). The role of precuneus and left inferior frontal cortex during source memory episodic retrieval. Neuroimage, 27, 824-834. doi:10.1016/j.neuroimage.2005.05.008.

    Abstract

    The posterior medial parietal cortex and left prefrontal cortex (PFC) have both been implicated in the recollection of past episodes. In a previous study, we found the posterior precuneus and left lateral inferior frontal cortex to be activated during episodic source memory retrieval. This study further examines the role of posterior precuneal and left prefrontal activation during episodic source memory retrieval using a similar source memory paradigm but with longer latency between encoding and retrieval. Our results suggest that both the precuneus and the left inferior PFC are important for regeneration of rich episodic contextual associations and that the precuneus activates in tandem with the left inferior PFC during correct source retrieval. Further, results suggest that the left ventro-lateral frontal region/ frontal operculum is involved in searching for task-relevant information (BA 47) and subsequent monitoring or scrutiny (BA 44/45) while regions in the dorsal inferior frontal cortex are important for information selection (BA 45/46).
  • MacDermot, K. D., Bonora, E., Sykes, N., Coupe, A.-M., Lai, C. S. L., Vernes, S. C., Vargha-Khadem, F., McKenzie, F., Smith, R. L., Monaco, A. P., & Fisher, S. E. (2005). Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits. American Journal of Human Genetics, 76(6), 1074-1080. doi:10.1086/430841.

    Abstract

    FOXP2, the first gene to have been implicated in a developmental communication disorder, offers a unique entry point into neuromolecular mechanisms influencing human speech and language acquisition. In multiple members of the well-studied KE family, a heterozygous missense mutation in FOXP2 causes problems in sequencing muscle movements required for articulating speech (developmental verbal dyspraxia), accompanied by wider deficits in linguistic and grammatical processing. Chromosomal rearrangements involving this locus have also been identified. Analyses of FOXP2 coding sequence in typical forms of specific language impairment (SLI), autism, and dyslexia have not uncovered any etiological variants. However, no previous study has performed mutation screening of children with a primary diagnosis of verbal dyspraxia, the most overt feature of the disorder in affected members of the KE family. Here, we report investigations of the entire coding region of FOXP2, including alternatively spliced exons, in 49 probands affected with verbal dyspraxia. We detected variants that alter FOXP2 protein sequence in three probands. One such variant is a heterozygous nonsense mutation that yields a dramatically truncated protein product and cosegregates with speech and language difficulties in the proband, his affected sibling, and their mother. Our discovery of the first nonsense mutation in FOXP2 now opens the door for detailed investigations of neurodevelopment in people carrying different etiological variants of the gene. This endeavor will be crucial for gaining insight into the role of FOXP2 in human cognition.
  • Mace, R., Jordan, F., & Holden, C. (2003). Testing evolutionary hypotheses about human biological adaptation using cross-cultural comparison. Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology, 136(1), 85-94. doi:10.1016/S1095-6433(03)00019-9.

    Abstract

    Physiological data from a range of human populations living in different environments can provide valuable information for testing evolutionary hypotheses about human adaptation. By taking into account the effects of population history, phylogenetic comparative methods can help us determine whether variation results from selection due to particular environmental variables. These selective forces could even be due to cultural traits-which means that gene-culture co-evolution may be occurring. In this paper, we outline two examples of the use of these approaches to test adaptive hypotheses that explain global variation in two physiological traits: the first is lactose digestion capacity in adults, and the second is population sex-ratio at birth. We show that lower than average sex ratio at birth is associated with high fertility, and argue that global variation in sex ratio at birth has evolved as a response to the high physiological costs of producing boys in high fertility populations.
  • Magnuson, J. S., Tanenhaus, M. K., Aslin, R. N., & Dahan, D. (2003). The time course of spoken word learning and recognition: Studies with artificial lexicons. Journal of Experimental Psychology: General, 132(2), 202-227. doi:10.1037/0096-3445.132.2.202.

    Abstract

    The time course of spoken word recognition depends largely on the frequencies of a word and its competitors, or neighbors (similar-sounding words). However, variability in natural lexicons makes systematic analysis of frequency and neighbor similarity difficult. Artificial lexicons were used to achieve precise control over word frequency and phonological similarity. Eye tracking provided time course measures of lexical activation and competition (during spoken instructions to perform visually guided tasks) both during and after word learning, as a function of word frequency, neighbor type, and neighbor frequency. Apparent shifts from holistic to incremental competitor effects were observed in adults and neural network simulations, suggesting such shifts reflect general properties of learning rather than changes in the nature of lexical representations.
  • Magyari, L. (2003). Mit ne gondoljunk az állatokról? [What not to think about animals?] [Review of the book Wild Minds: What animals really think by M. Hauser]. Magyar Pszichológiai Szemle (Hungarian Psychological Review), 58(3), 417-424. doi:10.1556/MPSzle.58.2003.3.5.
  • Majid, A. (2003). Towards behavioural genomics. The Psychologist, 16(6), 298-298.
  • Majid, A. (2003). Into the deep. The Psychologist, 16(6), 300-300.
  • Mangione-Smith, R., Stivers, T., Elliott, M. N., McDonald, L., & Heritage, J. (2003). Online commentary during the physical examination: A communication tool for avoiding inappropriate antibiotic prescribing? Social Science and Medicine, 56(2), 313-320.

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