Publications

Displaying 201 - 300 of 542
  • Kempen, G., & Van Wijk, C. (1980). Leren formuleren: Hoe uit opstellen een objektieve index voor formuleervaardigheid afgeleid kan worden. De Psycholoog, 15, 609-621.
  • Kempen, G., & Kolk, H. (1986). Het voortbrengen van normale en agrammatische taal. Van Horen Zeggen, 27(2), 36-40.
  • Kempen, G. (2014). Prolegomena to a neurocomputational architecture for human grammatical encoding and decoding. Neuroinformatics, 12, 111-142. doi:10.1007/s12021-013-9191-4.

    Abstract

    The study develops a neurocomputational architecture for grammatical processing in language production and language comprehension (grammatical encoding and decoding, respectively). It seeks to answer two questions. First, how is online syntactic structure formation of the complexity required by natural-language grammars possible in a fixed, preexisting neural network without the need for online creation of new connections or associations? Second, is it realistic to assume that the seemingly disparate instantiations of syntactic structure formation in grammatical encoding and grammatical decoding can run on the same neural infrastructure? This issue is prompted by accumulating experimental evidence for the hypothesis that the mechanisms for grammatical decoding overlap with those for grammatical encoding to a considerable extent, thus inviting the hypothesis of a single “grammatical coder.” The paper answers both questions by providing the blueprint for a syntactic structure formation mechanism that is entirely based on prewired circuitry (except for referential processing, which relies on the rapid learning capacity of the hippocampal complex), and can subserve decoding as well as encoding tasks. The model builds on the “Unification Space” model of syntactic parsing developed by Vosse & Kempen (2000, 2008, 2009). The design includes a neurocomputational mechanism for the treatment of an important class of grammatical movement phenomena.
  • Kempen, G. (1987). Tekstverwerking: De vijfde generatie. Informatie, 29, 402-406.
  • Kempen, G. (1986). RIKS: Kennistechnologisch centrum voor bedrijfsleven en wetenschap. Informatie, 28, 122-125.
  • Kempen, G. (1988). Preface. Acta Psychologica, 69(3), 205-206. doi:10.1016/0001-6918(88)90032-7.
  • Kempen, G. (1997). Van taalbarrières naar linguïstische snelwegen: Inrichting van een technische taalinfrastructuur voor het Nederlands. Grenzen aan veeltaligheid: Taalgebruik en bestuurlijke doeltreffendheid in de instellingen van de Europese Unie, 43-48.
  • Kersten, R. W. J., Van Gastel, B. E., Shkaravska, O., Montenegro, M., & Van Eekelen, M. C. J. D. (2014). ResAna: a resource analysis toolset for (real-time) JAVA. Concurrency and Computing: Practice and Experience, 26, 2432-2455. doi:10.1002/cpe.3154.

    Abstract

    For real-time and embedded systems, limiting the consumption of time and memory resources is often an important part of the requirements. Being able to predict bounds on the consumption of such resources during the development process of the code can be of great value. In this paper, we focus mainly on memory-related bounds. Recent research results have advanced the state of the art of resource consumption analysis. In this paper, we present a toolset that makes it possible to apply these research results in practice for (real-time) systems enabling JAVA developers to analyse symbolic loop bounds, symbolic bounds on heap size and both symbolic and numeric bounds on stack size. We describe which theoretical additions were needed in order to achieve this. We give an overview of the capabilities of the RESANA (Radboud University Nijmegen, The Netherlands) toolset that is the result of this effort. The toolset can not only perform generally applicable analyses, but it also contains a part of the analysis that is dedicated to the developers' (real-time) virtual machine, such that the results apply directly to the actual development environment that is used in practice
  • Kita, S., Van Gijn, I., & Van Der Hulst, H. (2014). The non-linguistic status of the Symmetry Condition in signed languages: Evidence from a comparison of signs and speechaccompanying representational gestures. Sign language and linguistics, 17(2), 215-238.

    Abstract

    Since Battison (1978), it has been noted in many signed languages that the Symmetry Condition constrains the form of two-handed signs in which two hands move independently. The Condition states that the form features (e.g., the handshapes and movements) of the two hands are 'symmetrical'. The Symmetry Condition has been regarded in the literature as a part of signed language phonology. In this study, we examine the linguistic status of the Symmetry Condition by comparing the degree of symmetry in signs from Sign Language of the Netherlands and speech-accompanying representational gestures produced by Dutch speakers. Like signed language, such gestures use hand movements to express concepts, but they do not constitute a linguistic system in their own right. We found that the Symmetry Condition holds equally well for signs and spontaneous gestures. This indicates that this condition is a general cognitive constraint, rather than a constraint specific to language. We suggest that the Symmetry Condition is a manifestation of the mind having one active 'mental articulator' when expressing a concept with hand movements
  • Kita, S. (1997). Two-dimensional semantic analysis of Japanese mimetics. Linguistics, 35, 379-415. doi:10.1515/ling.1997.35.2.379.
  • Klein, W., & Musan, R. (Eds.). (1999). Das deutsche Perfekt [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (113).
  • Klein, W. (1987). Das Geltende, oder: System der Überzeugungen. Zeitschrift für Literaturwissenschaft und Linguistik, (64), 10-31.
  • Klein, W., & Rieck, B.-O. (1982). Der Erwerb der Personalpronomina im ungesteuerten Spracherwerb. Zeitschrift für Literaturwissenschaft und Linguistik, 45, 35-71.
  • Klein, W. (1980). Der stand der Forschung zur deutschen Satzintonation. Linguistische Berichte, 68/80, 3-33.
  • Klein, W. (1986). Der Wahn vom Sprachverfall und andere Mythen. Zeitschrift für Literaturwissenschaft und Linguistik, 62, 11-28.
  • Klein, W. (1987). Eine Verschärfung des Entscheidungsproblems. Rechtshistorisches Journal, 6, 209-210.
  • Klein, W. (1982). Einige Bemerkungen zur Frageintonation. Deutsche Sprache, 4, 289-310.

    Abstract

    In the first, critical part of this study, a small sample of simple German sentences with their empirically determined pitch contours is used to demonstrate the incorrectness of numerous currently hold views of German sentence intonation. In the second, more constructive part, several interrogative sentence types are analysed and an attempt is made to show that intonation, besides other functions, indicates the permantently changing 'thematic score' in on-going discourse as well as certain validity claims.
  • Klein, W. (1982). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 12, 7-8.
  • Klein, W. (1986). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 16(62), 9-10.
  • Klein, W. (1988). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 18(69), 7-8.
  • Klein, W. (2000). An analysis of the German perfekt. Language, 76, 358-382.

    Abstract

    The German Perfekt has two quite different temporal readings, as illustrated by the two possible continuations of the sentence Peter hat gearbeitet in i, ii, respectively: (i) Peter hat gearbeitet und ist müde. Peter has worked and is tired. (ii) Peter hat gearbeitet und wollte nicht gestört werden. Peter has worked and wanted not to be disturbed. The first reading essentially corresponds to the English present perfect; the second can take a temporal adverbial with past time reference ('yesterday at five', 'when the phone rang', and so on), and an English translation would require a past tense ('Peter worked/was working'). This article shows that the Perfekt has a uniform temporal meaning that results systematically from the interaction of its three components-finiteness marking, auxiliary and past participle-and that the two readings are the consequence of a structural ambiguity. This analysis also predicts the properties of other participle constructions, in particular the passive in German.
  • Klein, W. (Ed.). (1980). Argumentation [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (38/39).
  • Klein, W. (1980). Argumentation und Argument. Zeitschrift für Literaturwissenschaft und Linguistik, 38/39, 9-57.
  • Klein, W., Li, P., & Hendriks, H. (2000). Aspect and assertion in Mandarin Chinese. Natural Language & Linguistic Theory, 18, 723-770. doi:10.1023/A:1006411825993.

    Abstract

    Chinese has a number of particles such as le, guo, zai and zhe that add a particular aspectual value to the verb to which they are attached. There have been many characterisations of this value in the literature. In this paper, we review several existing influential accounts of these particles, including those in Li and Thompson (1981), Smith (1991), and Mangione and Li (1993). We argue that all these characterisations are intuitively plausible, but none of them is precise.We propose that these particles serve to mark which part of the sentence''s descriptive content is asserted, and that their aspectual value is a consequence of this function. We provide a simple and precise definition of the meanings of le, guo, zai and zhe in terms of the relationship between topic time and time of situation, and show the consequences of their interaction with different verb expressions within thisnew framework of interpretation.
  • Klein, W. (1980). Der Stand der Forschung zur deutschen Satzintonation. Linguistische Berichte, (68/80), 3-33.
  • Klein, W. (2014). Is aspect time-relational? Commentary on the paper by Jürgen Bohnemeyer. Natural Language & Linguistic Theory, 32(3), 955-971. doi:10.1007/s11049-014-9240-1.

    Abstract

    Tense is traditionally assumed to express temporal relations between the time of the event and the moment of speech, whereas aspect expresses various views on one and the same event. In Klein (1994), it was argued that the intuitions which underlie this viewing metaphor can be made precise by a time-relational analysis as well. In his article “Aspect vs. relative tense: the case reopened”, Jürgen Bohnemeyer challenges one important point of this analysis, the equation of aspect and relative tense in the English perfect and in temporal forms of few other languages. In the present comment, it is argued that this is indeed a simplification, which does not speak, however, against a time-relational analysis of aspect in general. The main lines of such an analysis for the English perfect are sketched. It is shown that it naturally accounts for differences between the simple past and the present perfect, as well as for the oddity of constructions such as Einstein has visited Princeton or Ira has left yesterday at five.
  • Klein, W. (2000). Fatale Traditionen. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (120), 11-40.
  • Klein, W. (1997). Learner varieties are the normal case. The Clarion, 3, 4-6.
  • Klein, W. (1997). Nobels Vermächtnis, oder die Wandlungen des Idealischen. Zeitschrift für Literaturwissenschaft und Linguistik, 107, 6-18.

    Abstract

    Nobel's legacy, or the metamorphosis of what is idealistic Ever since the first Nobel prize in literature was awarded to Prudhomme in 1901, the decisions of the Swedish Academy have been subject to criticism. What is surprising in the changing decision policy as well as in its criticism is the fact that Alfred Nobel's original intentions are hardly ever taken into account: the Nobel prize is a philanthropic prize, it is not meant to select and honour the most eminent literary work but the work with maximal benefit to human beings. What is even more surprising is the fact that no one seems to care that the donator's Last Will is regularly broken.
  • Klein, W. (1982). Pronoms personnels et formes d'acquisition. Encrages, 8/9, 42-46.
  • Klein, W., & Von Stutterheim, C. (1987). Quaestio und referentielle Bewegung in Erzählungen. Linguistische Berichte, 109, 163-183.
  • Klein, W. (Ed.). (1997). Technologischer Wandel in den Philologien [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (106).
  • Klein, W., & Perdue, C. (1997). The basic variety (or: Couldn't natural languages be much simpler?). Second Language Research, 13, 301-347. doi:10.1191/026765897666879396.

    Abstract

    In this article, we discuss the implications of the fact that adult second language learners (outside the classroom) universally develop a well-structured, efficient and simple form of language–the Basic Variety (BV). Three questions are asked as to (1) the structural properties of the BV, (2) the status of these properties and (3) why some structural properties of ‘fully fledged’ languages are more complex. First, we characterize the BV in four respects: its lexical repertoire, the principles according to which utterances are structured, and temporality and spatiality expressed. The organizational principles proposed are small in number, and interact. We analyse this interaction, describing how the BV is put to use in various complex verbal tasks, in order to establish both what its communicative potentialities are, and also those discourse contexts where the constraints come into conflict and where the variety breaks down. This latter phenomenon provides a partial answer to the third question,concerning the relative complexity of ‘fully fledged’ languages–they have devices to deal with such cases. As for the second question, it is argued firstly that the empirically established continuity of the adult acquisition process precludes any assignment of the BV to a mode of linguistic expression (e.g., ‘protolanguage’) distinct from that of ‘fully fledged’ languages and, moreover, that the organizational constraints of the BV belong to the core attributes of the human language capacity, whereas a number of complexifications not attested in the BV are less central properties of this capacity. Finally, it is shown that the notion of feature strength, as used in recent versions of Generative Grammar, allows a straightforward characterization of the BV as a special case of an I-language, in the sense of this theory. Under this perspective, the acquisition of an Ilanguage beyond the BV can essentially be described as a change in feature strength.
  • Klein, W. (1980). Some remarks on Sanders' typology of elliptical coordinations. Linguistics, 18, 871-876.

    Abstract

    Starting with Ross (1970), various proposals have been made to classify elliptical coordinations and to characterize different languages according to the types of ellipses which they admit. Sanders (1977) discusses four of these proposals, shows that they are inadequate on various grounds and proposes a fifth typology whose central claim is 'evidently correct', as he states (p. 258). In the following, I shall briefly outline this typology and then show that it is inadequate, too. Since there is only one language 1 know — German — I will take all my examples from this language. Moreover, all examples will be straightforward and easy to be judged.
  • Klein, W. (Ed.). (2000). Sprache des Rechts [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (118).
  • Klein, W., & Berliner Arbeitsgruppe (2000). Sprache des Rechts: Vermitteln, Verstehen, Verwechseln. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (118), 7-33.
  • Klein, W. (Ed.). (1988). Sprache Kranker [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (69).
  • Klein, W. (1988). Sprache und Krankheit: Ein paar Anmerkungen. Zeitschrift für Literaturwissenschaft und Linguistik, 69, 9-20.
  • Klein, W. (Ed.). (1987). Sprache und Ritual [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (65).
  • Klein, W. (Ed.). (1986). Sprachverfall [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (62).
  • Klein, W. (1980). Vorwort. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 10, 7-8.
  • Klein, W. (2000). Was uns die Sprache des Rechts über die Sprache sagt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (118), 115-149.
  • Klein, W. (1999). Wie sich das deutsche Perfekt zusammensetzt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (113), 52-85.
  • Klein, W. (Ed.). (1982). Zweitspracherwerb [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (45).
  • Klein, W. (1986). Über Ansehen und Wirkung der deutschen Sprachwissenschaft heute. Linguistische Berichte, 100, 511-520.
  • Klenova, A. V., Goncharova, M. V., Bragina, E. V., & Kashentseva, T. A. (2014). Vocal development and voice breaking in Demoiselle Cranes (Anthropoides virgo). Bioacoustics, 23, 247-265. doi:10.1080/09524622.2014.900648.

    Abstract

    The vocal development of cranes (Gruidae) has attracted scientific interest due to a
    special stage, so-called voice breaking. During voice breaking, chicks produce both
    adult low-frequency and juvenile high-frequency vocalizations. The triggers that affect voice breaking are unknown. For the first time, we study the vocal development of the Demoiselle Crane (Anthropoides virgo). We describe the age and possible drivers of
    the onset of voice breaking. We analyse the calls of 21 Demoiselle Crane chicks, and
    compare them with the calls of six adult birds, noting the day when adult low-frequency calls are first recorded as the day when voice breaking begins. The age of voice
    breaking onset does not depend on hatching date, clutch order or chick body mass. Thus, there is no correlation between body growth and the onset of voice breaking for individual Demoiselle Crane chicks. However, there is a strong relationship between body mass and voice breaking among different crane species. Demoiselle Cranes stop intense body growth at the age of 2 months and start voice breaking at 70 ^ 46 days. By way of comparison, Red-crowned Cranes finish the period of intense body growth at the age of 7 months and start voice breaking at 211 ^ 60 days. Thus, we show that the Demoiselle Crane has a sudden vocal development, similar to other crane species, and we suggest that the end of intense body growth is the trigger for the onset of voice breaking in cranes.
  • Knudsen, B., Fischer, M., & Aschersleben, G. (2014). Development of Spatial Preferences for Counting and Picture Naming. Psychological Research, 79, 939-949. doi:10.1007/s00426-014-0623-z.

    Abstract

    The direction of object enumeration reflects children’s enculturation but previous work on the development of such spatial preferences has been inconsistent. Therefore, we documented directional preferences in finger counting, object counting, and picture naming for children (4 groups from 3 to 6 years, N = 104) and adults (N = 56). We found a right-side preference for finger counting in 3- to 6-year-olds and a left-side preference for counting objects and naming pictures by 6 years of age. Children were consistent in their special preferences when comparing object counting and picture naming, but not in other task pairings. Finally, spatial preferences were not related to cardinality comprehension. These results, together with other recent work, suggest a gradual development of spatial-numerical associations from early non-directional mappings into culturally constrained directional mappings.
  • Kong, X. (2014). Association between in-scanner head motion with cerebral white matter microstructure: a multiband diffusion-weighted MRI study. PeerJ, 2: e366. doi:10.7717/peerj.366.

    Abstract

    Diffusion-weighted Magnetic Resonance Imaging (DW-MRI) has emerged as the most popular neuroimaging technique used to depict the biological microstructural properties of human brain white matter. However, like other MRI techniques, traditional DW-MRI data remains subject to head motion artifacts during scanning. For example, previous studies have indicated that, with traditional DW-MRI data, head motion artifacts significantly affect the evaluation of diffusion metrics. Actually, DW-MRI data scanned with higher sampling rate are important for accurately evaluating diffusion metrics because it allows for full-brain coverage through the acquisition of multiple slices simultaneously and more gradient directions. Here, we employed a publicly available multiband DW-MRI dataset to investigate the association between motion and diffusion metrics with the standard pipeline, tract-based spatial statistics (TBSS). The diffusion metrics used in this study included not only the commonly used metrics (i.e., FA and MD) in DW-MRI studies, but also newly proposed inter-voxel metric, local diffusion homogeneity (LDH). We found that the motion effects in FA and MD seems to be mitigated to some extent, but the effect on MD still exists. Furthermore, the effect in LDH is much more pronounced. These results indicate that researchers shall be cautious when conducting data analysis and interpretation. Finally, the motion-diffusion association is discussed.
  • Kong, X., Zhen, Z., Li, X., Lu, H.-h., Wang, R., Liu, L., He, Y., Zang, Y., & Liu, J. (2014). Individual Differences in Impulsivity Predict Head Motion during Magnetic Resonance Imaging. PLoS One, 9(8): e104989. doi:10.1371/journal.pone.0104989.

    Abstract

    Magnetic resonance imaging (MRI) provides valuable data for understanding the human mind and brain disorders, but in-scanner head motion introduces systematic and spurious biases. For example, differences in MRI measures (e.g., network strength, white matter integrity) between patient and control groups may be due to the differences in their head motion. To determine whether head motion is an important variable in itself, or just simply a confounding variable, we explored individual differences in psychological traits that may predispose some people to move more than others during an MRI scan. In the first two studies, we demonstrated in both children (N  =  245) and adults (N  =  581) that head motion, estimated from resting-state functional MRI and diffusion tensor imaging, was reliably correlated with impulsivity scores. Further, the difference in head motion between children with attention deficit hyperactivity disorder (ADHD) and typically developing children was largely due to differences in impulsivity. Finally, in the third study, we confirmed the observation that the regression approach, which aims to deal with motion issues by regressing out motion in the group analysis, would underestimate the effect of interest. Taken together, the present findings provide empirical evidence that links in-scanner head motion to psychological traits.
  • Kong, X., Wang, X., Huang, L., Pu, Y., Yang, Z., Dang, X., Zhen, Z., & Liu, J. (2014). Measuring individual morphological relationship of cortical regions. Journal of Neuroscience Methods, 237, 103-107. doi:10.1016/j.jneumeth.2014.09.003.

    Abstract

    Background Although local features of brain morphology have been widely investigated in neuroscience, the inter-regional relations in brain morphology have rarely been investigated, especially not for individual participants. New method In this paper, we proposed a novel framework for investigating this relation based on an individual's magnetic resonance imaging (MRI) data. The key idea was to estimate the probability density function (PDF) of local morphological features within a brain region to provide a global description of this region. Then, the inter-regional relations were quantified by calculating the similarity of the PDFs for pairs of regions based on the Kullback–Leibler (KL) divergence. Results For illustration, we applied this approach to a pre-post intervention study to investigate the longitudinal changes in morphological relations after long-term sleep deprivation. The results suggest the potential application of this new method for studies on individual differences in brain structure. Comparison with existing methods The current method can be employed to estimate individual morphological relations between regions, which have been largely ignored by previous studies. Conclusions Our morphological relation metric, as a novel quantitative biomarker, can be used to investigate normal individual variability and even within-individual alterations/abnormalities in brain structure.
  • Konopka, A. E., & Meyer, A. S. (2014). Priming sentence planning. Cognitive Psychology, 73, 1-40. doi:10.1016/j.cogpsych.2014.04.001.

    Abstract

    Sentence production requires mapping preverbal messages onto linguistic structures. Because sentences are normally built incrementally, the information encoded in a sentence-initial increment is critical for explaining how the mapping process starts and for predicting its timecourse. Two experiments tested whether and when speakers prioritize encoding of different types of information at the outset of formulation by comparing production of descriptions of transitive events (e.g., A dog is chasing the mailman) that differed on two dimensions: the ease of naming individual characters and the ease of apprehending the event gist (i.e., encoding the relational structure of the event). To additionally manipulate ease of encoding, speakers described the target events after receiving lexical primes (facilitating naming; Experiment 1) or structural primes (facilitating generation of a linguistic structure; Experiment 2). Both properties of the pictured events and both types of primes influenced the form of target descriptions and the timecourse of formulation: character-specific variables increased the probability of speakers encoding one character with priority at the outset of formulation, while the ease of encoding event gist and of generating a syntactic structure increased the likelihood of early encoding of information about both characters. The results show that formulation is flexible and highlight some of the conditions under which speakers might employ different planning strategies.
  • Kösem, A., Gramfort, A., & van Wassenhove, V. (2014). Encoding of event timing in the phase of neural oscillations. NeuroImage, 92, 274-284. doi:10.1016/j.neuroimage.2014.02.010.

    Abstract

    ime perception is a critical component of conscious experience. To be in synchrony with the environment, the brain must deal not only with differences in the speed of light and sound but also with its computational and neural transmission delays. Here, we asked whether the brain could actively compensate for temporal delays by changing its processing time. Specifically, can changes in neural timing or in the phase of neural oscillation index perceived timing? For this, a lag-adaptation paradigm was used to manipulate participants' perceived audiovisual (AV) simultaneity of events while they were recorded with magnetoencephalography (MEG). Desynchronized AV stimuli were presented rhythmically to elicit a robust 1 Hz frequency-tagging of auditory and visual cortical responses. As participants' perception of AV simultaneity shifted, systematic changes in the phase of entrained neural oscillations were observed. This suggests that neural entrainment is not a passive response and that the entrained neural oscillation shifts in time. Crucially, our results indicate that shifts in neural timing in auditory cortices linearly map participants' perceived AV simultaneity. To our knowledge, these results provide the first mechanistic evidence for active neural compensation in the encoding of sensory event timing in support of the emergence of time awareness.
  • De Kovel, C. G. F., Meisler, M. H., Brilstra, E. H., van Berkestijn, F. M. C., van 't Slot, R., van Lieshout, S., Nijman, I. J., O'Brien, J. E., Hammer, M. F., Estacion, M., Waxman, S. G., Dib-Hajj, S. D., & Koeleman, B. P. C. (2014). Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy. Epilepsy Research, 108(9), 1511-1518. doi:10.1016/j.eplepsyres.2014.08.020.

    Abstract

    Objective Recently, de novo SCN8A missense mutations have been identified as a rare dominant cause of epileptic encephalopathies. Functional studies on the first described case demonstrated gain-of-function effects of the mutation. We describe a novel de novo mutation of SCN8A in a patient with epileptic encephalopathy, and functional characterization of the mutant protein. Design Whole exome sequencing was used to discover the variant. We generated a mutant cDNA, transfected HEK293 cells, and performed Western blotting to assess protein stability. To study channel functional properties, patch-clamp experiments were carried out in transfected neuronal ND7/23 cells. Results The proband exhibited seizure onset at 6 months of age, diffuse brain atrophy, and more profound developmental impairment than the original case. The mutation p.Arg233Gly in the voltage sensing transmembrane segment D1S4 was present in the proband and absent in both parents. This mutation results in a temperature-sensitive reduction in protein expression as well as reduced sodium current amplitude and density and a relative increased response to a slow ramp stimulus, though this did not result in an absolute increased current at physiological temperatures. Conclusion The new de novo SCN8A mutation is clearly deleterious, resulting in an unstable protein with reduced channel activity. This differs from the gain-of-function attributes of the first SCN8A mutation in epileptic encephalopathy, pointing to heterogeneity of mechanisms. Since Nav1.6 is expressed in both excitatory and inhibitory neurons, a differential effect of a loss-of-function of Nav1.6 Arg223Gly on inhibitory interneurons may underlie the epilepsy phenotype in this patient.
  • Kunert, R., & Scheepers, C. (2014). Speed and accuracy of dyslexic versus typical word recognition: An eye-movement investigation. Frontiers in Psychology, 5: 1129. doi:10.3389/fpsyg.2014.01129.

    Abstract

    Developmental dyslexia is often characterized by a dual deficit in both word recognition accuracy and general processing speed. While previous research into dyslexic word recognition may have suffered from speed-accuracy trade-off, the present study employed a novel eye-tracking task that is less prone to such confounds. Participants (10 dyslexics and 12 controls) were asked to look at real word stimuli, and to ignore simultaneously presented non-word stimuli, while their eye-movements were recorded. Improvements in word recognition accuracy over time were modeled in terms of a continuous non-linear function. The words' rhyme consistency and the non-words' lexicality (unpronounceable, pronounceable, pseudohomophone) were manipulated within-subjects. Speed-related measures derived from the model fits confirmed generally slower processing in dyslexics, and showed a rhyme consistency effect in both dyslexics and controls. In terms of overall error rate, dyslexics (but not controls) performed less accurately on rhyme-inconsistent words, suggesting a representational deficit for such words in dyslexics. Interestingly, neither group showed a pseudohomophone effect in speed or accuracy, which might call the task-independent pervasiveness of this effect into question. The present results illustrate the importance of distinguishing between speed- vs. accuracy-related effects for our understanding of dyslexic word recognition

    Additional information

    Kunert_Data Sheet 1.DOCX
  • Kupisch, T., Lein, T., Barton, D., Schröder, D. J., Stangen, I., & Stoehr, A. (2014). Acquisition outcomes across domains in adult simultaneous bilinguals with French as weaker and stronger language. Journal of French Language Studies, 24(3), 347-376. doi:10.1017/S0959269513000197.

    Abstract

    This study investigates the adult grammars of French simultaneous bilingual speakers (2L1s) whose other language is German. Apart from providing an example of French as heritage language in Europe, the goals of this paper are (i) to compare the acquisition of French in a minority and majority language context, (ii) to identify the relative vulnerability of individual domains, and (iii) to investigate whether 2L1s are vulnerable to language attrition when moving to their heritage country during adulthood. We include two groups of German-French 2L1s: One group grew up predominantly in France, but moved to Germany during adulthood; the other group grew up predominantly in Germany and stayed there. Performance is compared in different domains, including adjective placement, gender marking, articles, prepositions, foreign accent and voice onset time. Results indicate that differences between the two groups are minimal in morpho-syntax, but more prominent in pronunciation.
  • Kushnick, G., Gray, R., & Jordan, F. (2014). The sequential evolution of land tenure norms. Evolution and Human Behavior, 35, 309-318. doi:10.1016/j.evolhumbehav.2014.03.001.
  • Lahey, M., & Ernestus, M. (2014). Pronunciation variation in infant-directed speech: Phonetic reduction of two highly frequent words. Language Learning and Development, 10, 308-327. doi:10.1080/15475441.2013.860813.

    Abstract

    In spontaneous conversations between adults, words are often pronounced with fewer segments or syllables than their citation forms. The question arises whether infant-directed speech also contains phonetic reduction. If so, infants would be presented with speech input that enables them to acquire reduced variants from an early age. This study compared speech directed at 11- and 12-month-old infants with adult-directed conversational speech and adult-directed read speech. In an acoustic study, 216 tokens of the Dutch words allemaal and helemaal from speech corpora were analyzed for duration, number of syllables, and vowel quality. In a perception study, adult participants rated these same materials for reduction and provided phonetic transcriptions. The results show that these two words are frequently reduced in infant-directed speech, and that their degree of reduction is comparable with conversational adult-directed speech. These findings suggest that lexical representations for reduced pronunciation variants can be acquired early in linguistic development

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  • Lai, C. S. L., Fisher, S. E., Hurst, J. A., Levy, E. R., Hodgson, S., Fox, M., Jeremiah, S., Povey, S., Jamison, D. C., Green, E. D., Vargha-Khadem, F., & Monaco, A. P. (2000). The SPCH1 region on human 7q31: Genomic characterization of the critical interval and localization of translocations associated with speech and language disorder. American Journal of Human Genetics, 67(2), 357-368. doi:10.1086/303011.

    Abstract

    The KE family is a large three-generation pedigree in which half the members are affected with a severe speech and language disorder that is transmitted as an autosomal dominant monogenic trait. In previously published work, we localized the gene responsible (SPCH1) to a 5.6-cM region of 7q31 between D7S2459 and D7S643. In the present study, we have employed bioinformatic analyses to assemble a detailed BAC-/PAC-based sequence map of this interval, containing 152 sequence tagged sites (STSs), 20 known genes, and >7.75 Mb of completed genomic sequence. We screened the affected chromosome 7 from the KE family with 120 of these STSs (average spacing <100 kb), but we did not detect any evidence of a microdeletion. Novel polymorphic markers were generated from the sequence and were used to further localize critical recombination breakpoints in the KE family. This allowed refinement of the SPCH1 interval to a region between new markers 013A and 330B, containing ∼6.1 Mb of completed sequence. In addition, we have studied two unrelated patients with a similar speech and language disorder, who have de novo translocations involving 7q31. Fluorescence in situ hybridization analyses with BACs/PACs from the sequence map localized the t(5;7)(q22;q31.2) breakpoint in the first patient (CS) to a single clone within the newly refined SPCH1 interval. This clone contains the CAGH44 gene, which encodes a brain-expressed protein containing a large polyglutamine stretch. However, we found that the t(2;7)(p23;q31.3) breakpoint in the second patient (BRD) resides within a BAC clone mapping >3.7 Mb distal to this, outside the current SPCH1 critical interval. Finally, we investigated the CAGH44 gene in affected individuals of the KE family, but we found no mutations in the currently known coding sequence. These studies represent further steps toward the isolation of the first gene to be implicated in the development of speech and language.
  • Lai, V. T., Garrido Rodriguez, G., & Narasimhan, B. (2014). Thinking-for-speaking in early and late bilinguals. Bilingualism: Language and Cognition, 17, 139-152. doi:10.1017/S1366728913000151.

    Abstract

    When speakers describe motion events using different languages, they subsequently classify those events in language-specific ways (Gennari, Sloman, Malt & Fitch, 2002). Here we ask if bilingual speakers flexibly shift their event classification preferences based on the language in which they verbally encode those events. English–Spanish bilinguals and monolingual controls described motion events in either Spanish or English. Subsequently they judged the similarity of the motion events in a triad task. Bilinguals tested in Spanish and Spanish monolinguals were more likely to make similarity judgments based on the path of motion versus bilinguals tested in English and English monolinguals. The effect is modulated in bilinguals by the age of acquisition of the second language. Late bilinguals based their judgments on path more often when Spanish was used to describe the motion events versus English. Early bilinguals had a path preference independent of the language in use. These findings support “thinking-for-speaking” (Slobin, 1996) in late bilinguals.
  • Lartseva, A., Dijkstra, T., Kan, C. C., & Buitelaar, J. K. (2014). Processing of emotion words by patients with Autism Spectrum Disorders: Evidence from reaction times and EEG. Journal of Autism and Developmental Disorders, 44, 2882-2894. doi:10.1007/s10803-014-2149-z.

    Abstract

    This study investigated processing of emotion words in autism spectrum disorders (ASD) using reaction times and event-related potentials (ERP). Adults with (n = 21) and without (n = 20) ASD performed a lexical decision task on emotion and neutral words while their brain activity was recorded. Both groups showed faster responses to emotion words compared to neutral, suggesting intact early processing of emotion in ASD. In the ERPs, the control group showed a typical late positive component (LPC) at 400-600 ms for emotion words compared to neutral, while the ASD group showed no LPC. The between-group difference in LPC amplitude was significant, suggesting that emotion words were processed differently by individuals with ASD, although their behavioral performance was similar to that of typical individuals
  • Lemhoefer, K., Schriefers, H., & Indefrey, P. (2014). Idiosyncratic Grammars: Syntactic Processing in Second Language Comprehension Uses Subjective Feature Representations. Journal of Cognitive Neuroscience, 26(7), 1428-1444. doi:10.1162/jocn_a_00609.

    Abstract

    Learning the syntax of a second language (L2) often represents a big challenge to L2 learners. Previous research on syntactic processing in L2 has mainly focused on how L2 speakers respond to "objective" syntactic violations, that is, phrases that are incorrect by native standards. In this study, we investigate how L2 learners, in particular those of less than near-native proficiency, process phrases that deviate from their own, "subjective," and often incorrect syntactic representations, that is, whether they use these subjective and idiosyncratic representations during sentence comprehension. We study this within the domain of grammatical gender in a population of German learners of Dutch, for which systematic errors of grammatical gender are well documented. These L2 learners as well as a control group of Dutch native speakers read Dutch sentences containing gender-marked determinernoun phrases in which gender agreement was either (objectively) correct or incorrect. Furthermore, the noun targets were selected such that, in a high proportion of nouns, objective and subjective correctness would differ for German learners. The ERP results show a syntactic violation effect (P600) for objective gender agreement violations for native, but not for nonnative speakers. However, when the items were re-sorted for the L2 speakers according to subjective correctness (as assessed offline), the P600 effect emerged as well. Thus, rather than being insensitive to violations of gender agreement, L2 speakers are similarly sensitive as native speakers but base their sensitivity on their subjective-sometimes incorrect-representations.

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  • Lensink, S. E., Verdonschot, R. G., & Schiller, N. O. (2014). Morphological priming during language switching: An ERP study. Frontiers in Human Neuroscience, 8: 995. doi:10.3389/fnhum.2014.00995.

    Abstract

    Bilingual language control (BLC) is a much-debated issue in recent literature. Some models assume BLC is achieved by various types of inhibition of the non-target language, whereas other models do not assume any inhibitory mechanisms. In an event-related potential (ERP) study involving a long-lag morphological priming paradigm, participants were required to name pictures and read aloud words in both their L1 (Dutch) and L2 (English). Switch blocks contained intervening L1 items between L2 primes and targets, whereas non-switch blocks contained only L2 stimuli. In non-switch blocks, target picture names that were morphologically related to the primes were named faster than unrelated control items. In switch blocks, faster response latencies were recorded for morphologically related targets as well, demonstrating the existence of morphological priming in the L2. However, only in non-switch blocks, ERP data showed a reduced N400 trend, possibly suggesting that participants made use of a post-lexical checking mechanism during the switch block.
  • Lev-Ari, S., & Peperkamp, S. (2014). An experimental study of the role of social factors in sound change. Laboratory Phonology, 5(3), 379-401. doi:10.1515/lp-2014-0013.

    Abstract

    There is great variation in whether foreign sounds in loanwords are adapted or retained. Importantly, the retention of foreign sounds can lead to a sound change in the language. We propose that social factors influence the likelihood of loanword sound adaptation, and use this case to introduce a novel experimental paradigm for studying language change that captures the role of social factors. Specifically, we show that the relative prestige of the donor language in the loanword's semantic domain influences the rate of sound adaptation. We further show that speakers adapt to the performance of their ‘community’, and that this adaptation leads to the creation of a norm. The results of this study are thus the first to show an effect of social factors on loanword sound adaptation in an experimental setting. Moreover, they open up a new domain of experimentally studying language change in a manner that integrates social factors
  • Lev-Ari, S., & Keysar, B. (2014). Executive control influences linguistic representations. Memory & Cognition, 42(2), 247-263. doi:10.3758/s13421-013-0352-3.

    Abstract

    Although it is known that words acquire their meanings partly from the contexts in which they are used, we proposed that the way in which words are processed can also influence their representation. We further propose that individual differences in the way that words are processed can consequently lead to individual differences in the way that they are represented. Specifically, we showed that executive control influences linguistic representations by influencing the coactivation of competing and reinforcing terms. Consequently, people with poorer executive control perceive the meanings of homonymous terms as being more similar to one another, and those of polysemous terms as being less similar to one another, than do people with better executive control. We also showed that bilinguals with poorer executive control experience greater cross-linguistic interference than do bilinguals with better executive control. These results have implications for theories of linguistic representation and language organization.
  • Lev-Ari, S., San Giacomo, M., & Peperkamp, S. (2014). The effect of domain prestige and interlocutors’ bilingualism on sound adaptation. Journal of Sociolinguistics, 18(5), 658-684. doi:10.1111/josl.12102.

    Abstract

    There is great variability in whether foreign sounds in loanwords are adapted, such that segments show cross-word and cross-situational variation in adaptation. Previous research proposed that word frequency, speakers' level of bilingualism and neighborhoods' level of bilingualism can explain such variability. We test for the effect of these factors and propose two additional factors: interlocutors' level of bilingualism and the prestige of the donor language in the loanword's domain. Analyzing elicited productions of loanwords from Spanish into Mexicano in a village where Spanish and Mexicano enjoy prestige in complementary domains, we show that interlocutors' bilingualism and prestige influence the rate of sound adaptation. Additionally, we find that speakers accommodate to their interlocutors, regardless of the interlocutors' level of bilingualism. As retention of foreign sounds can lead to sound change, these results show that social factors can influence changes in a language's sound system.
  • Lev-Ari, S., & Peperkamp, S. (2014). The influence of inhibitory skill on phonological representations in production and perception. Journal of Phonetics, 47, 36-46. doi:10.1016/j.wocn.2014.09.001.

    Abstract

    Inhibition is known to play a role in speech perception and has been hypothesized to likewise influence speech production. In this paper we test whether individual differences in inhibitory skill can lead to individual differences in phonological representations in perception and production. We further examine whether the type of inhibition that influences phonological representation is domain-specific or domain-general. Native French speakers read aloud sentences with words containing a voiced stop that either have a voicing neighbor (target) or not (control). The duration of pre-voicing was measured. Participants similarly performed a lexical decision task on versions of these target and matched control words whose pre-voicing duration was manipulated. Lastly, participants performed linguistic and non-linguistic inhibition tasks. Results indicate that the lower speakers' linguistic or non-linguistic inhibition is, the easier it is for them to recognize words with a voiceless neighbor when these words have a shorter, intermediate, pre-voicing rather than a longer one. Inhibitory skill did not predict recognition time for control words, indicating that the effect was due to the greater activation of the voiceless neighbor. Inhibition did not predict pre-voicing duration in production. These results indicate that individual differences in cognitive skills can influence phonological representations in speech perception.
  • Levelt, W. J. M. (2000). Uit talloos veel miljoenen. Natuur & Techniek, 68(11), 90.
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (1999). A developmental grammar for syllable structure in the production of child language. Brain and Language, 68, 291-299.

    Abstract

    The order of acquisition of Dutch syllable types by first language learners is analyzed as following from an initial ranking and subsequent rerankings of constraints in an optimality theoretic grammar. Initially, structural constraints are all ranked above faithfulness constraints, leading to core syllable (CV) productions only. Subsequently, faithfulness gradually rises to the highest position in the ranking, allowing more and more marked syllable types to appear in production. Local conjunctions of Structural constraints allow for a more detailed analysis.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). A theory of lexical access in speech production. Behavioral and Brain Sciences, 22, 1-38. doi:10.1017/S0140525X99001776.

    Abstract

    Preparing words in speech production is normally a fast and accurate process. We generate them two or three per second in fluent conversation; and overtly naming a clear picture of an object can easily be initiated within 600 msec after picture onset. The underlying process, however, is exceedingly complex. The theory reviewed in this target article analyzes this process as staged and feedforward. After a first stage of conceptual preparation, word generation proceeds through lexical selection, morphological and phonological encoding, phonetic encoding, and articulation itself. In addition, the speaker exerts some degree of output control, by monitoring of self-produced internal and overt speech. The core of the theory, ranging from lexical selection to the initiation of phonetic encoding, is captured in a computational model, called WEAVER + +. Both the theory and the computational model have been developed in interaction with reaction time experiments, particularly in picture naming or related word production paradigms, with the aim of accounting. for the real-time processing in normal word production. A comprehensive review of theory, model, and experiments is presented. The model can handle some of the main observations in the domain of speech errors (the major empirical domain for most other theories of lexical access), and the theory opens new ways of approaching the cerebral organization of speech production by way of high-temporal-resolution imaging.
  • Levelt, W. J. M. (2000). Dyslexie. Natuur & Techniek, 68(4), 64.
  • Levelt, W. J. M. (1999). Models of word production. Trends in Cognitive Sciences, 3, 223-232.

    Abstract

    Research on spoken word production has been approached from two angles. In one research tradition, the analysis of spontaneous or induced speech errors led to models that can account for speech error distributions. In another tradition, the measurement of picture naming latencies led to chronometric models accounting for distributions of reaction times in word production. Both kinds of models are, however, dealing with the same underlying processes: (1) the speaker’s selection of a word that is semantically and syntactically appropriate; (2) the retrieval of the word’s phonological properties; (3) the rapid syllabification of the word in context; and (4) the preparation of the corresponding articulatory gestures. Models of both traditions explain these processes in terms of activation spreading through a localist, symbolic network. By and large, they share the main levels of representation: conceptual/semantic, syntactic, phonological and phonetic. They differ in various details, such as the amount of cascading and feedback in the network. These research traditions have begun to merge in recent years, leading to highly constructive experimentation. Currently, they are like two similar knives honing each other. A single pair of scissors is in the making.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). Multiple perspectives on lexical access [authors' response ]. Behavioral and Brain Sciences, 22, 61-72. doi:10.1017/S0140525X99451775.
  • Levelt, W. J. M. (1997). Kunnen lezen is ongewoon voor horenden en doven. Tijdschrift voor Jeugdgezondheidszorg, 29(2), 22-25.
  • Levelt, W. J. M. (1982). Het lineariseringsprobleem van de spreker. Tijdschrift voor Taal- en Tekstwetenschap (TTT), 2(1), 1-15.
  • Levelt, W. J. M. (2000). Links en rechts: Waarom hebben we zo vaak problemen met die woorden? Natuur & Techniek, 68(7/8), 90.
  • Levelt, W. J. M. (1988). Onder sociale wetenschappen. Mededelingen van de Afdeling Letterkunde, 51(2), 41-55.
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (2000). The acquisition of syllable types. Language Acquisition, 8(3), 237-263. doi:10.1207/S15327817LA0803_2.

    Abstract

    In this article, we present an account of developmental data regarding the acquisition of syllable types. The data come from a longitudinal corpus of phonetically transcribed speech of 12 children acquiring Dutch as their first language. A developmental order of acquisition of syllable types was deduced by aligning the syllabified data on a Guttman scale. This order could be analyzed as following from an initial ranking and subsequent rerankings in the grammar of the structural constraints ONSET, NO-CODA, *COMPLEX-O, and *COMPLEX-C; some local conjunctions of these constraints; and a faithfulness constraint FAITH. The syllable type frequencies in the speech surrounding the language learner are also considered. An interesting correlation is found between the frequencies and the order of development of the different syllable types.
  • Levelt, W. J. M. (2000). The brain does not serve linguistic theory so easily [Commentary to target article by Grodzinksy]. Behavioral and Brain Sciences, 23(1), 40-41.
  • Levelt, W. J. M., & Kelter, S. (1982). Surface form and memory in question answering. Cognitive Psychology, 14, 78-106. doi:10.1016/0010-0285(82)90005-6.

    Abstract

    Speakers tend to repeat materials from previous talk. This tendency is experimentally established and manipulated in various question-answering situations. It is shown that a question's surface form can affect the format of the answer given, even if this form has little semantic or conversational consequence, as in the pair Q: (At) what time do you close. A: “(At)five o'clock.” Answerers tend to match the utterance to the prepositional (nonprepositional) form of the question. This “correspondence effect” may diminish or disappear when, following the question, additional verbal material is presented to the answerer. The experiments show that neither the articulatory buffer nor long-term memory is normally involved in this retention of recent speech. Retaining recent speech in working memory may fulfill a variety of functions for speaker and listener, among them the correct production and interpretation of surface anaphora. Reusing recent materials may, moreover, be more economical than regenerating speech anew from a semantic base, and thus contribute to fluency. But the realization of this strategy requires a production system in which linguistic formulation can take place relatively independent of, and parallel to, conceptual planning.
  • Levelt, W. J. M. (1982). Science policy: Three recent idols, and a goddess. IPO Annual Progress Report, 17, 32-35.
  • Levelt, W. J. M., & Meyer, A. S. (2000). Word for word: Multiple lexical access in speech production. European Journal of Cognitive Psychology, 12(4), 433-452. doi:10.1080/095414400750050178.

    Abstract

    It is quite normal for us to produce one or two million word tokens every year. Speaking is a dear occupation and producing words is at the core of it. Still, producing even a single word is a highly complex affair. Recently, Levelt, Roelofs, and Meyer (1999) reviewed their theory of lexical access in speech production, which dissects the word-producing mechanism as a staged application of various dedicated operations. The present paper begins by presenting a bird eye's view of this mechanism. We then square the complexity by asking how speakers control multiple access in generating simple utterances such as a table and a chair. In particular, we address two issues. The first one concerns dependency: Do temporally contiguous access procedures interact in any way, or do they run in modular fashion? The second issue concerns temporal alignment: How much temporal overlap of processing does the system tolerate in accessing multiple content words, such as table and chair? Results from picture-word interference and eye tracking experiments provide evidence for restricted cases of dependency as well as for constraints on the temporal alignment of access procedures.
  • Levelt, W. J. M. (1982). Zelfcorrecties in het spreekproces. KNAW: Mededelingen van de afdeling letterkunde, nieuwe reeks, 45(8), 215-228.
  • Levinson, S. C., & Majid, A. (2014). Differential ineffability and the senses. Mind & Language, 29, 407-427. doi:10.1111/mila.12057.

    Abstract

    neffability, the degree to which percepts or concepts resist linguistic coding, is a fairly unexplored nook of cognitive science. Although philosophical preoccupations with qualia or nonconceptual content certainly touch upon the area, there has been little systematic thought and hardly any empirical work in recent years on the subject. We argue that ineffability is an important domain for the cognitive sciences. For examining differential ineffability across the senses may be able to tell us important things about how the mind works, how different modalities talk to one another, and how language does, or does not, interact with other mental faculties.
  • Levinson, S. C. (1987). Implicature explicated? [Comment on Sperber and Wilson]. Behavioral and Brain Sciences, 10(4), 722-723.

    Abstract

    Comment on Sperber and Wilson
  • Levinson, S. C. (1999). Maxim. Journal of Linguistic Anthropology, 9, 144-147. doi:10.1525/jlin.1999.9.1-2.144.
  • Levinson, S. C. (1997). Language and cognition: The cognitive consequences of spatial description in Guugu Yimithirr. Journal of Linguistic Anthropology, 7(1), 98-131. doi:10.1525/jlin.1997.7.1.98.

    Abstract

    This article explores the relation between language and cognition by examining the case of "absolute" (cardinal direction) spatial description in the Australian aboriginal language Guugu Yimithirr. This kind of spatial description is incongruent with the "relative" (e.g., left/right/front/back) spatial description familiar in European languages. Building on Haviland's 1993 analysis of Guugu Yimithirr directionals in speech and gesture, a series of informal experiments were developed. It is shown that Guugu Yimithirr speakers predominantly code for nonverbal memory in "absolute" concepts congruent with their language, while a comparative sample of Dutch speakers do so in "relative" concepts. Much anecdotal evidence also supports this. The conclusion is that Whorfian effects may in fact be demonstrable in the spatial domain.
  • Levinson, S. C. (1997). Language and cognition: The cognitive consequences of spatial description in Guugu Yimithirr. Journal of Linguistic Anthropology, 7(1), 1-35. doi:10.1525/jlin.1997.7.1.98.
  • Levinson, S. C. (2014). Language and Wallace's problem [Review of the books More than nature needs: Language, mind and evolution by D. Bickerton and A natural history of human thinking by M. Tomasello]. Science, 344, 1458-1459. doi:10.1126/science.1252988.
  • Levinson, S. C. (1980). Speech act theory: The state of the art. Language teaching and linguistics: Abstracts, 5-24.

    Abstract

    Survey article
  • Levinson, S. C. (1987). Pragmatics and the grammar of anaphora: A partial pragmatic reduction of Binding and Control phenomena. Journal of Linguistics, 23, 379-434. doi:10.1017/S0022226700011324.

    Abstract

    This paper is one in a series that develops a pragmatic framework in loose confederation with Jay Atlas and Larry Horn: thus they may or may not be responsible for the ideas contained herein. Jay Atlas provided many comments which I have utilized or perverted as the case may be. The Australian data to which this framework is applied was collected with the financial and personal assistance of many people and agencies acknowledged separately below; but I must single out for special thanks John Haviland, who recommended the study of Guugu Yimidhirr anaphora to me and upon whose grammatical work on Guugu Yimidhirr this paper is but a minor (and perhaps flawed) elaboration. A grant from the British Academy allowed me to visit Haviland in September 1986 to discuss many aspects of Guugu Yimidhirr with him, and I am most grateful to the Academy for funding this trip and to Haviland for generously making available his time, his texts (from which I have drawn many examples, not always with specific acknowledgement) and most especially his expertise. Where I have diverged from his opinion I may well learn to regret it. I must also thank Nigel Vincent for putting me in touch with a number of recent relevant developments in syntax (only some of which I have been able to address) and for suggestions for numerous improvements. In addition, I have benefited immensely for comments on a distinct but related paper (Levinson, 1987) kindly provided by Jay Atlas, John Haviland, John Heritage, Phil Johnson-Laird, John Lyons, Tanya Reinhart, Emanuel Schegloff and an anonymous referee; and from comments on this paper by participants in the Cambridge Linguistics Department seminar where it was first presented (especial thanks to John Lyons and Huang Yan for further comments, and Mary Smith for a counter-example). Despite all this help, there are sure to be errors of data and analysis that I have persisted in. Aid in gathering the Australian data is acknowledged separately below.
  • Levinson, S. C., & Holler, J. (2014). The origin of human multi-modal communication. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 369(1651): 2013030. doi:10.1098/rstb.2013.0302.

    Abstract

    One reason for the apparent gulf between animal and human communication systems is that the focus has been on the presence or the absence of language as a complex expressive system built on speech. But language normally occurs embedded within an interactional exchange of multi-modal signals. If this larger perspective takes central focus, then it becomes apparent that human communication has a layered structure, where the layers may be plausibly assigned different phylogenetic and evolutionary origins—especially in the light of recent thoughts on the emergence of voluntary breathing and spoken language. This perspective helps us to appreciate the different roles that the different modalities play in human communication, as well as how they function as one integrated system despite their different roles and origins. It also offers possibilities for reconciling the ‘gesture-first hypothesis’ with that of gesture and speech having evolved together, hand in hand—or hand in mouth, rather—as one system.
  • Levinson, S. C. (2000). Yélî Dnye and the theory of basic color terms. Journal of Linguistic Anthropology, 10( 1), 3-55. doi:10.1525/jlin.2000.10.1.3.

    Abstract

    The theory of basic color terms was a crucial factor in the demise of linguistic relativity. The theory is now once again under scrutiny and fundamental revision. This article details a case study that undermines one of the central claims of the classical theory, namely that languages universally treat color as a unitary domain, to be exhaustively named. Taken together with other cases, the study suggests that a number of languages have only an incipient color terminology, raising doubts about the linguistic universality of such terminology.
  • Levy, J., Hagoort, P., & Démonet, J.-F. (2014). A neuronal gamma oscillatory signature during morphological unification in the left occipitotemporal junction. Human Brain Mapping, 35, 5847-5860. doi:10.1002/hbm.22589.

    Abstract

    Morphology is the aspect of language concerned with the internal structure of words. In the past decades, a large body of masked priming (behavioral and neuroimaging) data has suggested that the visual word recognition system automatically decomposes any morphologically complex word into a stem and its constituent morphemes. Yet the reliance of morphology on other reading processes (e.g., orthography and semantics), as well as its underlying neuronal mechanisms are yet to be determined. In the current magnetoencephalography study, we addressed morphology from the perspective of the unification framework, that is, by applying the Hold/Release paradigm, morphological unification was simulated via the assembly of internal morphemic units into a whole word. Trials representing real words were divided into words with a transparent (true) or a nontransparent (pseudo) morphological relationship. Morphological unification of truly suffixed words was faster and more accurate and additionally enhanced induced oscillations in the narrow gamma band (60–85 Hz, 260–440 ms) in the left posterior occipitotemporal junction. This neural signature could not be explained by a mere automatic lexical processing (i.e., stem perception), but more likely it related to a semantic access step during the morphological unification process. By demonstrating the validity of unification at the morphological level, this study contributes to the vast empirical evidence on unification across other language processes. Furthermore, we point out that morphological unification relies on the retrieval of lexical semantic associations via induced gamma band oscillations in a cerebral hub region for visual word form processing.
  • Lewis, A., Freeman-Mills, L., de la Calle-Mustienes, E., Giráldez-Pérez, R. M., Davis, H., Jaeger, E., Becker, M., Hubner, N. C., Nguyen, L. N., Zeron-Medina, J., Bond, G., Stunnenberg, H. G., Carvajal, J. J., Gomez-Skarmeta, J. L., Leedham, S., & Tomlinson, I. (2014). A polymorphic enhancer near GREM1 influences bowel cancer risk through diifferential CDX2 and TCF7L2 binding. Cell Reports, 8(4), Pages 983-990. doi:10.1016/j.celrep.2014.07.020.

    Abstract

    A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Mendelian-dominant predisposition to colorectal cancer (CRC). The underlying disease mechanism is strong, ectopic GREM1 overexpression in the intestinal epithelium. Here, we confirm that a common GREM1 polymorphism, rs16969681, is also associated with CRC susceptibility, conferring ∼20% differential risk in the general population. We hypothesized the underlying cause to be moderate differences in GREM1 expression. We showed that rs16969681 lies in a region of active chromatin with allele- and tissue-specific enhancer activity. The CRC high-risk allele was associated with stronger gene expression, and higher Grem1 mRNA levels increased the intestinal tumor burden in ApcMin mice. The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.
  • Lieber, R., & Baayen, R. H. (1997). A semantic principle of auxiliary selection in Dutch. Natural Language & Linguistic Theory, 15(4), 789-845.

    Abstract

    We propose that the choice between the auxiliaries hebben 'have' and zijn 'be' in Dutch is determined by a particular semantic feature of verbs. In particular we propose a feature of meaning [IEPS] for 'inferable eventual position or state' that characterizes whether the action denoted by the verb allows us to determine the eventual position or state of the verb's highest argument. It is argued that only verbs which exhibit the feature [+IEPS] or which obtain the feature compositionally in the syntax select zijn as their auxiliary. Our analysis is then compared to a number of other analyses of auxiliary selection in Dutch.

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  • Liszkowski, U. (2014). Two sources of meaning in infant communication: Preceding action contexts and act-accompanying characteristics. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 369(1651): 20130294. doi:10.1098/rstb.2013.0294.
  • Littauer, R., Roberts, S. G., Winters, J., Bailes, R., Pleyer, M., & Little, H. (2014). From the savannah to the cloud: Blogging evolutionary linguistics research. The Past, Present and Future of Language Evolution Research: Student Volume of the 9th International Conference on the Evolution of Language, 121-133.

    Abstract

    Over the last thirty years, evolutionary linguistics has grown as a data-driven, interdisciplinary field and received accelerated interest due to its adoption of modern research methodologies. This growth is dependant upon the methods used to both disseminate and foster discussion of research by the larger academic community. We argue that the internet is increasingly being used as an efficient means of finding and presenting research. The traditional journal format for disseminating knowledge was well-designed within the confines of print publication. With the tools afforded to us by technology and the internet, the evolutionary linguistics research community is able to compensate for the necessary shortcomings of the journal format. We evaluate examples of how research blogging has aided language scientists. We review the state of the field for online, real-time academic debate, by covering particular instances of post- publication review and their reaction. We conclude by considering how evolutionary linguistics as a field can potentially benefit from using the internet
  • Liu, C., Kong, X., Liu, X., Zhou, R., & Wu, B. (2014). Long-term total sleep deprivation reduces thalamic gray matter volume in healthy men. NeuroReport, 25(5), 320-323. doi:10.1097/WNR.0000000000000091.

    Abstract

    Sleep loss can alter extrinsic, task-related functional MRI signals involved in attention, memory, and executive function. However, the effects of sleep loss on brain structure have not been well characterized. Recent studies with patients with sleep disorders and animal models have demonstrated reduction of regional brain structure in the hippocampus and thalamus. In this study, using T1-weighted MRI, we examined the change of regional gray matter volume in healthy adults after long-term total sleep deprivation (∼72 h). Regional volume changes were explored using voxel-based morphometry with a paired two-sample t-test. The results revealed significant loss of gray matter volume in the thalamus but not in the hippocampus. No overall decrease in whole brain gray matter volume was noted after sleep deprivation. As expected, sleep deprivation significantly reduced visual vigilance as assessed by the continuous performance test, and this decrease was correlated significantly with reduced regional gray matter volume in thalamic regions. This study provides the first evidence for sleep loss-related changes in gray matter in the healthy adult brain.
  • Lloyd, S. E., Günther, W., Pearce, S. H. S., Thomson, A., Bianchi, M. L., Bosio, M., Craig, I. W., Fisher, S. E., Scheinman, S. J., Wrong, O., Jentsch, T. J., & Thakker, R. V. (1997). Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders. Human Molecular Genetics, 6(8), 1233-1239. doi:10.1093/hmg/6.8.1233.

    Abstract

    Mutations of the renal-specific chloride channel (CLCN5) gene, which is located on chromosome Xp11.22, are associated with hypercalciuric nephrolithiasis (kidney stones) in the Northern European and Japanese populations. CLCN5 encodes a 746 amino acid channel (CLC-5) that has approximately 12 transmembrane domains, and heterologous expression of wild-type CLC-5 in Xenopus oocytes has yielded outwardly rectifying chloride currents that were markedly reduced or abolished by these mutations. In order to assess further the structural and functional relationships of this recently cloned chloride channel, additional CLCN5 mutations have been identified in five unrelated families with this disorder. Three of these mutations were missense (G57V, G512R and E527D), one was a nonsense (R648Stop) and one was an insertion (30:H insertion). In addition, two of the mutations (30:H insertion and E527D) were demonstrated to be de novo, and the G57V and E527D mutations were identified in families of Afro-American and Indian origin, respectively. The G57V and 30:H insertion mutations represent the first CLCN5 mutations to be identified in the N-terminus region, and the R648Stop mutation, which has been observed previously in an unrelated family, suggests that this codon may be particularly prone to mutations. Heterologous expression of the mutations resulted in a marked reduction or abolition of the chloride currents, thereby establishing their functional importance. These results help to elucidate further the structure-function relationships of this renal chloride channel.
  • Lohmann, A., & Takada, T. (2014). Order in NP conjuncts in spoken English and Japanese. Lingua, 152, 48-64. doi:10.1016/j.lingua.2014.09.011.

    Abstract

    In the emerging field of cross-linguistic studies on language production, one particularly interesting line of inquiry is possible differences between English and Japanese in ordering words and phrases. Previous research gives rise to the idea that there is a difference in accessing meaning versus form during linearization between these two languages. This assumption is based on observations of language-specific effects of the length factor on the order of phrases (short-before-long in English, long-before-short in Japanese). We contribute to the cross-linguistic exploration of such differences by investigating the variables underlying the internal order of NP conjuncts in spoken English and Japanese. Our quantitative analysis shows that similar influences underlie the ordering process across the two languages. Thus we do not find evidence for the aforementioned difference in accessing meaning versus form with this syntactic phenomenon. With regard to length, Japanese also exhibits a short-before-long preference. However, this tendency is significantly weaker in Japanese than in English, which we explain through an attenuating influence of the typical Japanese phrase structure pattern on the universal effect of short phrases being more accessible. We propose that a similar interaction between entrenched long-before-short schemas and universal accessibility effects is responsible for the varying effects of length in Japanese.

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