Publications

Displaying 201 - 300 of 497
  • Indefrey, P. (2011). The spatial and temporal signatures of word production components: a critical update. Frontiers in Psychology, 2(255): 255. doi:10.3389/fpsyg.2011.00255.

    Abstract

    In the first decade of neurocognitive word production research the predominant approach was brain mapping, i.e., investigating the regional cerebral brain activation patterns correlated with word production tasks, such as picture naming and word generation. Indefrey and Levelt (2004) conducted a comprehensive meta-analysis of word production studies that used this approach and combined the resulting spatial information on neural correlates of component processes of word production with information on the time course of word production provided by behavioral and electromagnetic studies. In recent years, neurocognitive word production research has seen a major change toward a hypothesis-testing approach. This approach is characterized by the design of experimental variables modulating single component processes of word production and testing for predicted effects on spatial or temporal neurocognitive signatures of these components. This change was accompanied by the development of a broader spectrum of measurement and analysis techniques. The article reviews the findings of recent studies using the new approach. The time course assumptions of Indefrey and Levelt (2004) have largely been confirmed requiring only minor adaptations. Adaptations of the brain structure/function relationships proposed by Indefrey and Leven (2004) include the precise role of subregions of the left inferior frontal gyrus as well as a probable, yet to date unclear role of the inferior parietal cortex in word production.
  • Ingason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietilainen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., Gylfason, A., Gustafsson, O., Olason, P. I., Steinberg, S., Hansen, T., Jakobsen, K. D., Rasmussen, H. B., Giegling, I., Möller, H.-J., Hartmann, A. and 28 moreIngason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietilainen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., Gylfason, A., Gustafsson, O., Olason, P. I., Steinberg, S., Hansen, T., Jakobsen, K. D., Rasmussen, H. B., Giegling, I., Möller, H.-J., Hartmann, A., Crombie, C., Fraser, G., Walker, N., Lonnqvist, J., Suvisaari, J., Tuulio-Henriksson, A., Bramon, E., Kiemeney, L. A., Franke, B., Murray, R., Vassos, E., Toulopoulou, T., Mühleisen, T. W., Tosato, S., Ruggeri, M., Djurovic, S., Andreassen, O. A., Zhang, Z., Werge, T., Ophoff, R. A., Rietschel, M., Nöthen, M. M., Petursson, H., Stefansson, H., Peltonen, L., Collier, D., Stefansson, K., & St Clair, D. M. (2011). Copy number variations of chromosome 16p13.1 region associated with schizophrenia. Molecular Psychiatry, 16, 17-25. doi:10.1038/mp.2009.101.

    Abstract

    Deletions and reciprocal duplications of the chromosome 16p13.1 region have recently been reported in several cases of autism and mental retardation (MR). As genomic copy number variants found in these two disorders may also associate with schizophrenia, we examined 4345 schizophrenia patients and 35 079 controls from 8 European populations for duplications and deletions at the 16p13.1 locus, using microarray data. We found a threefold excess of duplications and deletions in schizophrenia cases compared with controls, with duplications present in 0.30% of cases versus 0.09% of controls (P=0.007) and deletions in 0.12 % of cases and 0.04% of controls (P>0.05). The region can be divided into three intervals defined by flanking low copy repeats. Duplications spanning intervals I and II showed the most significant (P=0.00010) association with schizophrenia. The age of onset in duplication and deletion carriers among cases ranged from 12 to 35 years, and the majority were males with a family history of psychiatric disorders. In a single Icelandic family, a duplication spanning intervals I and II was present in two cases of schizophrenia, and individual cases of alcoholism, attention deficit hyperactivity disorder and dyslexia. Candidate genes in the region include NTAN1 and NDE1. We conclude that duplications and perhaps also deletions of chromosome 16p13.1, previously reported to be associated with autism and MR, also confer risk of schizophrenia.
  • Janse, E., & Ernestus, M. (2011). The roles of bottom-up and top-down information in the recognition of reduced speech: Evidence from listeners with normal and impaired hearing. Journal of Phonetics, 39(3), 330-343. doi:10.1016/j.wocn.2011.03.005.
  • Janse, E. (2002). Time-compressing natural and synthetic speech. In Proceedings of 7th International Conference on Spoken Language Processing (pp. 1645-1648).
  • Janssen, D. P., Roelofs, A., & Levelt, W. J. M. (2002). Inflectional frames in language production. Language and Cognitive Processes, 17(3), 209-236. doi:10.1006/jmla.2001.2800.

    Abstract

    The authors report six implicit priming experiments that examined the production of inflected forms. Participants produced words out of small sets in response to prompts. The words differed in form or shared word-initial segments, which allowed for preparation. In constant inflectional sets, the words had the same number of inflectional suffixes, whereas in variable sets the number of suffixes differed. In the experiments, preparation effects were obtained, which were larger in the constant than in the variable sets. Control experiments showed that this difference in effect was not due to syntactic class or phonological form per se. The results are interpreted in terms of a slot-and-filler model of word production, in which inflectional frames, on the one hand, and stems and affixes, on the other hand, are independently spelled out on the basis of an abstract morpho-syntactic specification of the word, which is followed by morpheme-to-frame association.
  • Jasmin, K., & Casasanto, D. (2011). The QWERTY effect: How stereo-typing shapes the mental lexicon. In L. Carlson, C. Holscher, & T. Shipley (Eds.), Proceedings of the 33rd Annual Conference of the Cognitive Science Society. Austin, TX: Cognitive Science Society.
  • Jesse, A., & Mitterer, H. (2011). Pointing gestures do not influence the perception of lexical stress. In Proceedings of the 12th Annual Conference of the International Speech Communication Association (Interspeech 2011), Florence, Italy (pp. 2445-2448).

    Abstract

    We investigated whether seeing a pointing gesture influences the perceived lexical stress. A pitch contour continuum between the Dutch words “CAnon” (‘canon’) and “kaNON” (‘cannon’) was presented along with a pointing gesture during the first or the second syllable. Pointing gestures following natural recordings but not Gaussian functions influenced stress perception (Experiment 1 and 2), especially when auditory context preceded (Experiment 2). This was not replicated in Experiment 3. Natural pointing gestures failed to affect the categorization of a pitch peak timing continuum (Experiment 4). There is thus no convincing evidence that seeing a pointing gesture influences lexical stress perception.
  • Jesse, A., & McQueen, J. M. (2011). Positional effects in the lexical retuning of speech perception. Psychonomic Bulletin & Review, 18, 943-950. doi:10.3758/s13423-011-0129-2.

    Abstract

    Listeners use lexical knowledge to adjust to speakers’ idiosyncratic pronunciations. Dutch listeners learn to interpret an ambiguous sound between /s/ and /f/ as /f/ if they hear it word-finally in Dutch words normally ending in /f/, but as /s/ if they hear it in normally /s/-final words. Here, we examined two positional effects in lexically guided retuning. In Experiment 1, ambiguous sounds during exposure always appeared in word-initial position (replacing the first sounds of /f/- or /s/-initial words). No retuning was found. In Experiment 2, the same ambiguous sounds always appeared word-finally during exposure. Here, retuning was found. Lexically guided perceptual learning thus appears to emerge reliably only when lexical knowledge is available as the to-be-tuned segment is initially being processed. Under these conditions, however, lexically guided retuning was position independent: It generalized across syllabic positions. Lexical retuning can thus benefit future recognition of particular sounds wherever they appear in words.
  • Johnson, E., McQueen, J. M., & Huettig, F. (2011). Toddlers’ language-mediated visual search: They need not have the words for it. The Quarterly Journal of Experimental Psychology, 64, 1672-1682. doi:10.1080/17470218.2011.594165.

    Abstract

    Eye movements made by listeners during language-mediated visual search reveal a strong link between
    visual processing and conceptual processing. For example, upon hearing the word for a missing referent
    with a characteristic colour (e.g., “strawberry”), listeners tend to fixate a colour-matched distractor (e.g.,
    a red plane) more than a colour-mismatched distractor (e.g., a yellow plane). We ask whether these
    shifts in visual attention are mediated by the retrieval of lexically stored colour labels. Do children
    who do not yet possess verbal labels for the colour attribute that spoken and viewed objects have in
    common exhibit language-mediated eye movements like those made by older children and adults?
    That is, do toddlers look at a red plane when hearing “strawberry”? We observed that 24-montholds
    lacking colour term knowledge nonetheless recognized the perceptual–conceptual commonality
    between named and seen objects. This indicates that language-mediated visual search need not
    depend on stored labels for concepts.
  • Johnson, E. K., & Huettig, F. (2011). Eye movements during language-mediated visual search reveal a strong link between overt visual attention and lexical processing in 36-months-olds. Psychological Research, 75, 35-42. doi:10.1007/s00426-010-0285-4.

    Abstract

    The nature of children’s early lexical processing was investigated by asking what information 36-month-olds access and use when instructed to find a known but absent referent. Children readily retrieved stored knowledge about characteristic color, i.e. when asked to find an object with a typical color (e.g. strawberry), children tended to fixate more upon an object that had the same (e.g. red plane) as opposed to a different (e.g. yellow plane) color. They did so regardless of the fact that they have had plenty of time to recognize the pictures for what they are, i.e. planes not strawberries. These data represent the first demonstration that language-mediated shifts of overt attention in young children can be driven by individual stored visual attributes of known words that mismatch on most other dimensions. The finding suggests that lexical processing and overt attention are strongly linked from an early age.
  • Johnson, J. S., Sutterer, D. W., Acheson, D. J., Lewis-Peacock, J. A., & Postle, B. R. (2011). Increased alpha-band power during the retention of shapes and shape-location associations in visual short-term memory. Frontiers in Psychology, 2(128), 1-9. doi:10.3389/fpsyg.2011.00128.

    Abstract

    Studies exploring the role of neural oscillations in cognition have revealed sustained increases in alpha-band (∼8–14 Hz) power during the delay period of delayed-recognition short-term memory tasks. These increases have been proposed to reflect the inhibition, for example, of cortical areas representing task-irrelevant information, or of potentially interfering representations from previous trials. Another possibility, however, is that elevated delay-period alpha-band power (DPABP) reflects the selection and maintenance of information, rather than, or in addition to, the inhibition of task-irrelevant information. In the present study, we explored these possibilities using a delayed-recognition paradigm in which the presence and task relevance of shape information was systematically manipulated across trial blocks and electroencephalographic was used to measure alpha-band power. In the first trial block, participants remembered locations marked by identical black circles. The second block featured the same instructions, but locations were marked by unique shapes. The third block featured the same stimulus presentation as the second, but with pretrial instructions indicating, on a trial-by-trial basis, whether memory for shape or location was required, the other dimension being irrelevant. In the final block, participants remembered the unique pairing of shape and location for each stimulus. Results revealed minimal DPABP in each of the location-memory conditions, whether locations were marked with identical circles or with unique task-irrelevant shapes. In contrast, alpha-band power increases were observed in both the shape-memory condition, in which location was task irrelevant, and in the critical final condition, in which both shape and location were task relevant. These results provide support for the proposal that alpha-band oscillations reflect the retention of shape information and/or shape–location associations in short-term memory.
  • Johnson, E. K., Westrek, E., Nazzi, T., & Cutler, A. (2011). Infant ability to tell voices apart rests on language experience. Developmental Science, 14(5), 1002-1011. doi:10.1111/j.1467-7687.2011.01052.x.

    Abstract

    A visual fixation study tested whether seven-month-olds can discriminate between different talkers. The infants were first habituated to talkers producing sentences in either a familiar or unfamiliar language, then heard test sentences from previously unheard speakers, either in the language used for habituation, or in another language. When the language at test mismatched that in habituation, infants always noticed the change. When language remained constant and only talker altered, however, infants detected the change only if the language was the native tongue. Adult listeners with a different native tongue than the infants did not reproduce the discriminability patterns shown by the infants, and infants detected neither voice nor language changes in reversed speech; both these results argue against explanation of the native-language voice discrimination in terms of acoustic properties of the stimuli. The ability to identify talkers is, like many other perceptual abilities, strongly influenced by early life experience.
  • Jones, C. R., Pickles, A., Falcaro, M., Marsden, A. J., Happé, F., Scott, S. K., Sauter, D., Tregay, J., Phillips, R. J., Baird, G., Simonoff, E., & Charman, T. (2011). A multimodal approach to emotion recognition ability in autism spectrum disorders. Journal of Child Psychology and Psychiatry, 52(3), 275-285. doi:10.1111/j.1469-7610.2010.02328.x.

    Abstract

    Background: Autism spectrum disorders (ASD) are characterised by social and communication difficulties in day-to-day life, including problems in recognising emotions. However, experimental investigations of emotion recognition ability in ASD have been equivocal; hampered by small sample sizes, narrow IQ range and over-focus on the visual modality. Methods: We tested 99 adolescents (mean age 15;6 years, mean IQ 85) with an ASD and 57 adolescents without an ASD (mean age 15;6 years, mean IQ 88) on a facial emotion recognition task and two vocal emotion recognition tasks (one verbal; one non-verbal). Recognition of happiness, sadness, fear, anger, surprise and disgust were tested. Using structural equation modelling, we conceptualised emotion recognition ability as a multimodal construct, measured by the three tasks. We examined how the mean levels of recognition of the six emotions differed by group (ASD vs. non-ASD) and IQ (>= 80 vs. < 80). Results: There was no significant difference between groups for the majority of emotions and analysis of error patterns suggested that the ASD group were vulnerable to the same pattern of confusions between emotions as the non-ASD group. However, recognition ability was significantly impaired in the ASD group for surprise. IQ had a strong and significant effect on performance for the recognition of all six emotions, with higher IQ adolescents outperforming lower IQ adolescents. Conclusions: The findings do not suggest a fundamental difficulty with the recognition of basic emotions in adolescents with ASD.
  • De Jong, N. H., Feldman, L. B., Schreuder, R., Pastizzo, M., & Baayen, R. H. (2002). The processing and representation of Dutch and English compounds: Peripheral morphological, and central orthographic effects. Brain and Language, 81(1-3), 555-567. doi:10.1006/brln.2001.2547.

    Abstract

    In this study, we use the association between various measures of the morphological family and decision latencies to reveal the way in which the components of Dutch and English compounds are processed. The results show that for constituents of concatenated compounds in both languages, a position-related token count of the morphological family plays a role, whereas English open compounds show an effect of a type count, similar to the effect of family size for simplex words. When Dutch compounds are written with an artificial space, they reveal no effect of type count, which shows that the differential effect for the English open compounds is not superficial. The final experiment provides converging evidence for the lexical consequences of the space in English compounds. Decision latencies for English simplex words are better predicted from counts of the morphological family that include concatenated and hyphenated but not open family members.
  • Jordan, F. (2011). A phylogenetic analysis of the evolution of Austronesian sibling terminologies. Human Biology, 83, 297-321. doi:10.3378/027.083.0209.

    Abstract

    Social structure in human societies is underpinned by the variable expression of ideas about relatedness between different types of kin. We express these ideas through language in our kin terminology: to delineate who is kin and who is not, and to attach meanings to the types of kin labels associated with different individuals. Cross-culturally, there is a regular and restricted range of patterned variation in kin terminologies, and to date, our understanding of this diversity has been hampered by inadequate techniques for dealing with the hierarchical relatedness of languages (Galton’s Problem). Here I use maximum-likelihood and Bayesian phylogenetic comparative methods to begin to tease apart the processes underlying the evolution of kin terminologies in the Austronesian language family, focusing on terms for siblings. I infer (1) the probable ancestral states and (2) evolutionary models of change for the semantic distinctions of relative age (older/younger sibling) and relative sex (same sex/opposite-sex). Analyses show that early Austronesian languages contained the relative-age, but not the relative-sex distinction; the latter was reconstructed firmly only for the ancestor of Eastern Malayo-Polynesian languages. Both distinctions were best characterized by evolutionary models where the gains and losses of the semantic distinctions were equally likely. A multi-state model of change examined how the relative-sex distinction could be elaborated and found that some transitions in kin terms were not possible: jumps from absence to heavily elaborated were very unlikely, as was piece-wise dismantling of elaborate distinctions. Cultural ideas about what types of kin distinctions are important can be embedded in the semantics of language; using a phylogenetic evolutionary framework we can understand how those distinctions in meaning change through time.
  • Jordens, P. (2002). Finiteness in early child Dutch. Linguistics, 40(4), 687-765. doi:10.1515/ling.2002.029.
  • Kearns, R. K., Norris, D., & Cutler, A. (2002). Syllable processing in English. In Proceedings of the 7th International Conference on Spoken Language Processing [ICSLP 2002] (pp. 1657-1660).

    Abstract

    We describe a reaction time study in which listeners detected word or nonword syllable targets (e.g. zoo, trel) in sequences consisting of the target plus a consonant or syllable residue (trelsh, trelshek). The pattern of responses differed from an earlier word-spotting study with the same material, in which words were always harder to find if only a consonant residue remained. The earlier results should thus not be viewed in terms of syllabic parsing, but in terms of a universal role for syllables in speech perception; words which are accidentally present in spoken input (e.g. sell in self) can be rejected when they leave a residue of the input which could not itself be a word.
  • Kelly, S., Byrne, K., & Holler, J. (2011). Raising the stakes of communication: Evidence for increased gesture production as predicted by the GSA framework. Information, 2(4), 579-593. doi:10.3390/info2040579.

    Abstract

    Theorists of language have argued that co-­speech hand gestures are an
    intentional part of social communication. The present study provides evidence for these
    claims by showing that speakers adjust their gesture use according to their perceived relevance to the audience. Participants were asked to read about items that were and were not useful in a wilderness survival scenario, under the pretense that they would then
    explain (on camera) what they learned to one of two different audiences. For one audience (a group of college students in a dormitory orientation activity), the stakes of successful
    communication were low;; for the other audience (a group of students preparing for a
    rugged camping trip in the mountains), the stakes were high. In their explanations to the camera, participants in the high stakes condition produced three times as many
    representational gestures, and spent three times as much time gesturing, than participants in the low stakes condition. This study extends previous research by showing that the anticipated consequences of one’s communication—namely, the degree to which information may be useful to an intended recipient—influences speakers’ use of gesture.
  • Kempen, G., & Van Breugel, C. (2002). A workbench for visual-interactive grammar instruction at the secondary education level. In Proceedings of the 10th International CALL Conference (pp. 157-158). Antwerp: University of Antwerp.
  • Kempen, G. (1996). Human language technology can modernize writing and grammar instruction. In COLING '96 Proceedings of the 16th conference on Computational linguistics - Volume 2 (pp. 1005-1006). Stroudsburg, PA: Association for Computational Linguistics.
  • Kempen, G. (1996). Lezen, leren lezen, dyslexie: De auditieve basis van visuele woordherkenning. Nederlands Tijdschrift voor de Psychologie, 51, 91-100.
  • Kempen, G., & Janssen, S. (1996). Omspellen: Reuze(n)karwei of peule(n)schil? In H. Croll, & J. Creutzberg (Eds.), Proceedings of the 5e Dag van het Document (pp. 143-146). Projectbureau Croll en Creutzberg.
  • Kempen, G., & Harbusch, K. (2002). Rethinking the architecture of human syntactic processing: The relationship between grammatical encoding and decoding. In Proceedings of the 35th Meeting of the Societas Linguistica Europaea. University of Potsdam.
  • Kempen, G. (1996). Wetenschap op internet: Een voorstel voor de Nederlandse Psychonomie. Nieuwsbrief Nederlandse Vereniging voor Psychonomie, 3, 5-8.
  • Kidd, E., Stewart, A. J., & Serratrice, L. (2011). Children do not overcome lexical biases where adults do: The role of the referential scene in garden-path recovery. Journal of Child Language, 38(1), 222-234. doi:10.1017/s0305000909990316.

    Abstract

    In this paper we report on a visual world eye-tracking experiment that investigated the differing abilities of adults and children to use referential scene information during reanalysis to overcome lexical biases during sentence processing. The results showed that adults incorporated aspects of the referential scene into their parse as soon as it became apparent that a test sentence was syntactically ambiguous, suggesting they considered the two alternative analyses in parallel. In contrast, the children appeared not to reanalyze their initial analysis, even over shorter distances than have been investigated in prior research. We argue that this reflects the children's over-reliance on bottom-up, lexical cues to interpretation. The implications for the development of parsing routines are discussed
  • Kidd, E., & Bavin, E. L. (2002). English-speaking children's comprehension of relative clauses: Evidence for general-cognitive and language-specific constraints on development. Journal of Psycholinguistic Research, 31(6), 599-617. doi:10.1023/A:1021265021141.

    Abstract

    Children must possess some ability to process input in a meaningful manner to acquire language. The present study reports on data from an experiment investigating 3- to 5-year-old English-speaking children's understanding of restrictive relative clauses manipulated for embeddedness and focus. The results of the study showed that English-speaking children acquire right-branching before center-embedded structures. Comparisons made with data from Portuguese-speaking children suggest general-cognitive and language-specific constraints on development, and with respect to English, a “clause expansion” approach to processing in development
  • Kidd, E., Kemp, N., & Quinn, S. (2011). Did you have a choccie bickie this arvo? A quantitative look at Australian hypocoristics. Language Sciences, 33(3), 359-368. doi:10.1016/j.langsci.2010.11.006.

    Abstract

    This paper considers the use and representation of Australian hypocoristics (e.g., choccie → chocolate, arvo → afternoon). One-hundred-and-fifteen adult speakers of Australian English aged 17–84 years generated as many tokens of hypocoristics as they could in 10 min. The resulting corpus was analysed along a number of dimensions in an attempt to identify (i) general age- and gender-related trends in hypocoristic knowledge and use, and (ii) linguistic properties of each hypocoristic class. Following Bybee’s (1985, 1995) lexical network approach, we conclude that Australian hypocoristics are the product of the same linguistic processes that capture other inflectional morphological processes.
  • Kidd, E., & Kirjavainen, M. (2011). Investigating the contribution of procedural and declarative memory to the acquisition of past tense morphology: Evidence from Finnish. Language and Cognitive Processes, 26(4-6), 794-829. doi:10.1080/01690965.2010.493735.

    Abstract

    The present paper reports on a study that investigated the role of procedural and declarative memory in the acquisition of Finnish past tense morphology. Two competing models were tested. Ullman's (2004) declarative/procedural model predicts that procedural memory supports the acquisition of regular morphology, whereas declarative memory supports the acquisition of irregular morphology. In contrast, single-route approaches predict that declarative memory should support lexical learning, which in turn should predict morphological acquisition. One-hundred and twenty-four (N=124) monolingual Finnish-speaking children aged 4;0–6;7 completed tests of procedural and declarative memory, tests of vocabulary knowledge and nonverbal ability, and a test of past test knowledge. The results best supported the single-route approach, suggesting that this account best extends to languages that possess greater morphological complexity than English.
  • Kirsch, K., & Dittmar, N. (2002). [Review of the book Russlanddeutsche Sprachbiografien: Untersuchungen zur sprachlichen Integration von Aussiedlerfamilien by Katharina Meng]. Zeitschrift für Sprachwissenschaft, 21, 295-296.
  • Klein, W. (Ed.). (2002). Sprache des Rechts II [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, 128.
  • Klein, W., & Schlieben-Lange, B. (1996). Das Ich und die Sprache. Zeitschrift für Literaturwissenschaft und Linguistik, 101, 1-5.
  • Klein, W., & Meibauer, J. (2011). Einleitung. LiLi, Zeitschrift für Literaturwissenschaft und Linguistik, 41(162), 5-8.

    Abstract

    Nannten die Erwachsenen irgend einen Gegenstand und wandten sie sich dabei ihm zu, so nahm ich das wahr und ich begriff, daß der Gegenstand durch die Laute, die sie aussprachen, bezeichnet wurde, da sie auf ihn hinweisen wollten. Dies aber entnahm ich aus ihren Gebärden, der natürlichen Sprache aller Völker, der Sprache, die durch Mienen- und Augenspiel, durch die Bewegungen der Glieder und den Klang der Stimme die Empfindungen der Seele anzeigt, wenn diese irgend etwas begehrt, oder festhält, oder zurückweist, oder flieht. So lernte ich nach und nach verstehen, welche Dinge die Wörter bezeichneten, die ich wieder und wieder, an ihren bestimmten Stellen in verschiedenen Sätzen, aussprechen hörte. Und ich brachte, als nun mein Mund sich an diese Zeichen gewöhnt hatte, durch sie meine Wünsche zum Ausdruck. (Augustinus, Confessiones I, 8) Dies ist das Zitat eines Zitats: Zu Beginn der Philosophischen Untersuchungen führt Ludwig Wittgenstein diese Stelle aus Augustinus’ Bekenntnissen an, in denen dieser beschreibt, wie er seiner Erinnerung nach seine Muttersprache gelernt hat (Wittgenstein führt den lateinischen Text an und gibt dann seine Übersetzung, hier ist nur letztere zitiert). Sie bilden den Ausgangspunkt für Wittgensteins berühmte Überlegungen über die Funktionsweise der menschlichen Sprache und für seine Idee des Sprachspiels. Nun weiß man nicht, wie genau sich Augustinus wirklich erinnert und ob er sich all dies, wie so viel, was seither über den Spracherwerb gesagt und geschrieben wurde, bloß zurechtgelegt hat, in der Meinung, so müsse es sein. Aber anders als so vieles, was seither über den Spracherwerb gesagt und geschrieben wurde, ist es wunderbar formuliert und enthält zwei Momente, die in der wissenschaftlichen Forschung bis heute, wenn denn nicht bestritten, so doch oft nicht gesehen und dort, wo sie denn gesehen, nicht wirklich ernstgenommen wurden: A. Wir lernen die Sprache in der alltäglichen Kommunikation mit der sozialen Umgebung. B. Um eine Sprache zu lernen, genügt es nicht, diese Sprache zu hören; vielmehr benötigen wir eine Fülle an begleitender Information, wie hier Gestik und Mimik der Erwachsenen. Beides möchte man eigentlich für selbstverständlich halten. Herodot erzählt die berühmte Geschichte des Pharaos Psammetich, der wissen wollte, was die erste und eigentliche Sprache der Menschen sei, und befahl, zwei Neugeborene aufwachsen zu lassen, ohne dass jemand zu ihnen spricht; das erste Wort, das sie äußern, klang, so erzählt Herodot, wie das phrygische Wort für Brot, und so nahm man denn an, die Ursprache des Menschen sei das Phrygische. In dieser Vorstellung vom Spracherwerb spielt der Input aus der sozialen Umgebung nur insofern eine Rolle, als die eigentliche, von Geburt an vorhandene Sprache durch eine andere verdrängt werden kann: Kinder, die in einer englischsprachigen Umgebung aufwachsen, sprechen nicht die Ursprache. Diese Theorie gilt heute als obsolet. Sie ist aber in ihrer Einschätzung vom relativen Gewicht dessen, was an sprachlichem Wissen von Anfang an vorhanden ist, und dem, was der sozialen Umgebung entnommen werden muss, manchen neueren Theorien des Spracherwerbs nicht ganz fern: In der Chomsky’schen Idee der Universalgrammatik, theoretische Grundlage eines wesentlichen Teils der modernen Spracherwerbsforschung, ist „die Sprache” hauptsächlich etwas Angeborenes, insoweit gleich für alle Menschen und vom jeweiligen Input unabhängig. Das, was das Kind oder, beim Zweitspracherwerb, der erwachsene Lerner an Sprachlichem aus seiner Umgebung erfährt, wird nicht genutzt, um daraus bestimmte Regelhaftigkeiten abzuleiten und sich diese anzueignen; der Input fungiert eher als eine Art externer Auslöser für latent bereits vorhandenes Wissen. Für das Erlernen des Wortschatzes gilt dies sicher nicht. Es kann nicht angeboren sein, dass der Mond luna heißt. Für andere Bereiche der Sprache ist das Ausmaß des Angeborenen aber durchaus umstritten. Bei dieser Denkweise gilt das unter A Gesagte nicht. Die meisten modernen Spracherwerbsforscher schreiben dem Input ein wesentlich höheres Gewicht zu: Wir kopieren die charakteristischen Eigenschaften eines bestimmten sprachlichen Systems, indem wir den Input analysieren, um so die ihm zugrundeliegenden Regularitäten abzuleiten. Der Input tritt uns in Form von Schallfolgen (oder Gesten und später geschriebenen Zeichen) entgegen, die von anderen, die das System beherrschen, zu kommunikativen Zwecken verwendet werden. Diese Schallfolgen müssen die Lernenden in kleinere Einheiten zerlegen, diese mit Bedeutungen versehen und nach den Regularitäten abklopfen, denen gemäß sie sich zu komplexeren Ausdrücken verbinden lassen. Dies – und vieles andere – ist es, was das dem Menschen angeborene Sprachvermögen leistet, keine andere Spezies kann es (einem Pferd kann man so viel Chinesisch vorspielen, wie man will, es wird es nicht lernen). Aber auch wir könnten es nicht, wenn wir nur den Schall hätten. Wenn man, in einer Abwandlung des Psammetich’schen Versuchs, jemanden in ein Zimmer einsperren und tagaus tagein mit Chinesisch beschallen und im Übrigen gut versorgen würde, so würde er es, gleich ob als Kind oder als Erwachsener, nicht lernen. Vielleicht würde er einige strukturelle Eigenschaften des Schallstroms ausfindig machen; aber er würde auch nach Jahren kein Chinesisch können. Man benötigt den Schallstrom als sinnlich fassbaren Ausdruck der zugrundeliegenden Sprache, und man benötigt all die Informationen, die man der jeweiligen Redesituation oder aber seinem bereits vorhandenen anderweitigen Wissen entnehmen kann. Augustinus hat beides radikal vereinfacht; aber im Prinzip hat er Recht, und man sollte daher von der Spracherwerbsforschung erwarten, dass sie dies in Rechnung stellt. Das tut sie aber selten. Soweit sie überhaupt aus dem Gehäuse der Theorie tritt und sich den tatsächlichen Verlauf des Spracherwerbs anschaut, konzentriert sie sich weithin auf das, was die Kinder selbst sagen – dazu dienen ausgedehnte Corpora –, oder aber sie untersucht in experimentellen Settings, wie Kinder bestimmte Wörter oder Strukturen verstehen oder auch nicht verstehen. Das hat auch, wenn denn gut gemacht, einen hohen Aufschlusswert. Aber die eigentliche Verarbeitung des Inputs im doppelten Sinne – Schallwellen und Parallelinformation – wird selten in den Mittelpunkt des Interesses gerückt. Dies führt zu eigentümlichen Verzerrungen. So betrachtet man in der Spracherwerbsforschung vor allem deklarative Hauptsätze. Ein nicht unwesentlicher Teil dessen, was Kinder hören, besteht aber aus Imperativen („Tu das!“, „Tu das nicht!“). In solchen Imperativen gibt es normalerweise kein Subjekt. Ein intelligentes Kind muss daher zu dem Schluss kommen, dass das Deutsche in einem nicht unwesentlichen Teil seiner grammatischen Strukturen eine „pro drop-Sprache” ist, d.h. eine Sprache, in dem man das Subjekt weglassen kann. Kein Linguist käme auf diese Idee; sie entspricht aber den tatsächlichen Verhältnissen, und dies schlägt sich in dem Input, den das Kind verarbeiten muss, nieder. Dieses Heft befasst sich mit einer Spracherwerbssituation, in der – anders als beispielsweise bei einem Gespräch am Frühstückstisch – der Input in seiner doppelten Form gut zu überschauen ist, ohne dass die Situation, wie etwa bei einem kontrollierten Experiment, unnatürlich und der normalen Lernumgebung ferne wäre: mit dem Anschauen, Vorlesen und Lesen von Kinderbüchern. Man kann sich eine solche Situation als eine natürliche Ausweitung dessen vorstellen, was Augustinus beschreibt: Die Kinder hören, was die Erwachsenen sagen, und ihre Aufmerksamkeit wird auf bestimmte Dinge gerichtet, während sie hören und schauen – nur geht es hier nicht um einzelne Wörter, sondern um komplexe Ausdrücke und um komplexe, aber dennoch überschaubare begleitende Informationen. Nun haben Kinderbücher in der Spracherwerbsforschung durchaus eine Rolle gespielt. Dabei dienen sie – sei es als reine Folge von Bildern, sei es mit Text oder gar nur als Text – aber meistens nur als eine Art Vorlage für die Sprachproduktion der Kinder: Sie sollen aus der Vorlage eine Geschichte ableiten und in ihren eigenen Worten erzählen. Das bekannteste, aber keineswegs das einzige Beispiel sind die von Michael Bamberg, Ruth Berman und Dan Slobin in den 1980er Jahren initiierten „frog stories” – Nacherzählungen einer einfachen Bildgeschichte, die inzwischen in zahlreichen Sprachen vorliegen und viele Aufschlüsse über die unterschiedlichsten Aspekte der sich entwickelnden Sprachbeherrschung, von der Flexionsmorphologie bis zur Textstruktur, gebracht haben. Das ist gut und sinnvoll; aber im Grunde müsste man einen Schritt weiter gehen, nämlich gleichsam wir durch ein Mikroskop zu schauen, wie sich die Kinder ihre Regularitäten aus der Interaktion ableiten. Dies würde unsere Vorstellungen über den Verlauf des Spracherwerbs und die Gesetzlichkeiten, nach denen er erfolgt, wesentlich bereichern, vielleicht auf eine ganz neue Basis stellen. Die Beiträge dieses Heftes geben dafür eine Reihe von Beispielen, von denen nur ein kleines, aber besonders schlagendes erwähnt werden soll. Es gibt zahlreiche, auf Bildgeschichten beruhende Analysen, in denen untersucht wird, wie Kinder eine bestimmte Person oder eine Sache im fortlaufenden Diskurs benennen – ob sie etwa definite und indefinite Nominalausdrücke (ein Junge – der Junge), lexikalische oder pronominale Nominalphrasen (der Junge – er) oder gar leere Elemente (der Junge wacht auf und 0 schaut nach seinem Hund) richtig verwenden können. Das Bild, das die Forschung in diesem wesentlichen Teil der Sprachbeherrschung heute bietet, ist alles andere als einheitlich. So umfassen die Ansichten darüber, wann die Definit-Indefinit-Unterscheidung gemeistert wird, den größten Teil der Kindheit, je nachdem, welche Untersuchungen man zu Rate zieht. In dem Aufsatz von Katrin Dammann-Thedens wird deutlich, dass Kindern in einem bestimmen Alter oft überhaupt nicht klar ist, dass eine bestimmte Person, eine bestimmte Sache auf fortlaufenden Bildern dieselbe ist – auch wenn sie ähnlich aussieht –, und das ist bei Licht besehen ja auch keine triviale Frage. Diese Beobachtungen werfen ein ganz neues Licht auf die Idee der referentiellen Kontinuität im Diskurs und ihren Ausdruck durch nominale Ausdrücke wie die eben genannten. Vielleicht haben wir ganz falsche Vorstellungen darüber, wie Kinder die begleitende Information – hier durch die Bilder einer Geschichte geliefert – verstehen und damit für den Spracherwerb verarbeiten. Derlei Beobachtungen sind zunächst einmal etwas Punktuelles, keine Antworten, sondern Hinweise auf Dinge, die man bedenken muss. Aber ihre Analyse, und allgemeiner, ein genauerer Blick auf das, was sich tatsächlich abspielt, wenn Kinder sich Kinderbücher anschauen, mag uns vielleicht zu einem wesentlich tieferen Verständnis dessen führen, was beim Erwerb einer Sprache tatsächlich geschieht.
  • Klein, W., & Jungbluth, K. (Eds.). (2002). Deixis [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, 125.
  • Klein, W., & Jungbluth, K. (2002). Einleitung - Introduction. Zeitschrift für Literaturwissenschaft und Linguistik, 125, 5-9.
  • Klein, W., & Schlieben-Lange, B. (Eds.). (1996). Sprache und Subjektivität I [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (101).
  • Klein, W., & Schlieben-Lange, B. (Eds.). (1996). Sprache und Subjektivität II [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (102).
  • Klein, W., & Meibauer, J. (Eds.). (2011). Spracherwerb und Kinderliteratur [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, 162.
  • Klein, W. (Ed.). (1996). Zweitspracherwerb [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (104).
  • Knosche, T. R., & Bastiaansen, M. C. M. (2002). On the time resolution of event-related desynchronization: A simulation study. Clinical Neurophysiology, 113(5), 754-763. doi:10.1016/S1388-2457(02)00055-X.

    Abstract

    Objectives: To investigate the time resolution of different methods for the computation of event-related desynchronization/synchronization (ERD/ERS), including one based on Hilbert transform. Methods: In order to better understand the time resolution of ERD/ERS, which is a function of factors such as the exact computation method, the frequency under study, the number of trials, and the sampling frequency, we simulated sudden changes in oscillation amplitude as well as very short and closely spaced events. Results: Hilbert-based ERD yields very similar results to ERD integrated over predefined time intervals (block ERD), if the block length is half the period length of the studied frequency. ERD predicts the onset of a change in oscillation amplitude with an error margin of only 10–30 ms. On the other hand, the time the ERD response needs to climb to its full height after a sudden change in oscillation amplitude is quite long, i.e. between 200 and 500 ms. With respect to sensitivity to short oscillatory events, the ratio between sampling frequency and electroencephalographic frequency band plays a major role. Conclusions: (1) The optimal time interval for the computation of block ERD is half a period of the frequency under investigation. (2) Due to the slow impulse response, amplitude effects in the ERD may in reality be caused by duration differences. (3) Although ERD based on the Hilbert transform does not yield any significant advantages over classical ERD in terms of time resolution, it has some important practical advantages.
  • Koenigs, M., Acheson, D. J., Barbey, A. K., Soloman, J., Postle, B. R., & Grafman, J. (2011). Areas of left perisylvian cortex mediate auditory-verbal short-term memory. Neuropsychologia, 49(13), 3612-3619. doi:10.1016/j.neuropsychologia.2011.09.013.

    Abstract

    A contentious issue in memory research is whether verbal short-term memory (STM) depends on a neural system specifically dedicated to the temporary maintenance of information, or instead relies on the same brain areas subserving the comprehension and production of language. In this study, we examined a large sample of adults with acquired brain lesions to identify the critical neural substrates underlying verbal STM and the relationship between verbal STM and language processing abilities. We found that patients with damage to selective regions of left perisylvian cortex – specifically the inferior frontal and posterior temporal sectors – were impaired on auditory–verbal STM performance (digit span), as well as on tests requiring the production and/or comprehension of language. These results support the conclusion that verbal STM and language processing are mediated by the same areas of left perisylvian cortex.

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  • Kokal, I., Engel, A., Kirschner, S., & Keysers, C. (2011). Synchronized drumming enhances activity in the caudate and facilitates prosocial commitment - If the rhythm comes easily. PLoS One, 6(11), e27272. doi:10.1371/journal.pone.0027272.

    Abstract

    Why does chanting, drumming or dancing together make people feel united? Here we investigate the neural mechanisms underlying interpersonal synchrony and its subsequent effects on prosocial behavior among synchronized individuals. We hypothesized that areas of the brain associated with the processing of reward would be active when individuals experience synchrony during drumming, and that these reward signals would increase prosocial behavior toward this synchronous drum partner. 18 female non-musicians were scanned with functional magnetic resonance imaging while they drummed a rhythm, in alternating blocks, with two different experimenters: one drumming in-synchrony and the other out-of-synchrony relative to the participant. In the last scanning part, which served as the experimental manipulation for the following prosocial behavioral test, one of the experimenters drummed with one half of the participants in-synchrony and with the other out-of-synchrony. After scanning, this experimenter "accidentally" dropped eight pencils, and the number of pencils collected by the participants was used as a measure of prosocial commitment. Results revealed that participants who mastered the novel rhythm easily before scanning showed increased activity in the caudate during synchronous drumming. The same area also responded to monetary reward in a localizer task with the same participants. The activity in the caudate during experiencing synchronous drumming also predicted the number of pencils the participants later collected to help the synchronous experimenter of the manipulation run. In addition, participants collected more pencils to help the experimenter when she had drummed in-synchrony than out-of-synchrony during the manipulation run. By showing an overlap in activated areas during synchronized drumming and monetary reward, our findings suggest that interpersonal synchrony is related to the brain's reward system.
  • Kucera, K. S., Reddy, T. E., Pauli, F., Gertz, J., Logan, J. E., Myers, R. M., & Willard, H. F. (2011). Allele-specific distribution of RNA polymerase II on female X chromosomes. Human Molecular Genetics, 20, 3964-3973. doi:10.1093/hmg/ddr315.

    Abstract

    While the distribution of RNA polymerase II (PolII) in a variety of complex genomes is correlated with gene expression, the presence of PolII at a gene does not necessarily indicate active expression. Various patterns of PolII binding have been described genome wide; however, whether or not PolII binds at transcriptionally inactive sites remains uncertain. The two X chromosomes in female cells in mammals present an opportunity to examine each of the two alleles of a given locus in both active and inactive states, depending on which X chromosome is silenced by X chromosome inactivation. Here, we investigated PolII occupancy and expression of the associated genes across the active (Xa) and inactive (Xi) X chromosomes in human female cells to elucidate the relationship of gene expression and PolII binding. We find that, while PolII in the pseudoautosomal region occupies both chromosomes at similar levels, it is significantly biased toward the Xa throughout the rest of the chromosome. The general paucity of PolII on the Xi notwithstanding, detectable (albeit significantly reduced) binding can be observed, especially on the evolutionarily younger short arm of the X. PolII levels at genes that escape inactivation correlate with the levels of their expression; however, additional PolII sites can be found at apparently silenced regions, suggesting the possibility of a subset of genes on the Xi that are poised for expression. Consistent with this hypothesis, we show that a high proportion of genes associated with PolII-accessible sites, while silenced in GM12878, are expressed in other female cell lines.
  • Kuijpers, C., Van Donselaar, W., & Cutler, A. (2002). Perceptual effects of assimilation-induced violation of final devoicing in Dutch. In J. H. L. Hansen, & B. Pellum (Eds.), The 7th International Conference on Spoken Language Processing (pp. 1661-1664). Denver: ICSA.

    Abstract

    Voice assimilation in Dutch is an optional phonological rule which changes the surface forms of words and in doing so may violate the otherwise obligatory phonological rule of syllablefinal devoicing. We report two experiments examining the influence of voice assimilation on phoneme processing, in lexical compound words and in noun-verb phrases. Processing was not impaired in appropriate assimilation contexts across morpheme boundaries, but was impaired when devoicing was violated (a) in an inappropriate non-assimilatory) context, or (b) across a syntactic boundary.
  • Kuijpers, C., Van Donselaar, W., & Cutler, A. (1996). Phonological variation: Epenthesis and deletion of schwa in Dutch. In H. T. Bunnell (Ed.), Proceedings of the Fourth International Conference on Spoken Language Processing: Vol. 1 (pp. 94-97). New York: Institute of Electrical and Electronics Engineers.

    Abstract

    Two types of phonological variation in Dutch, resulting from optional rules, are schwa epenthesis and schwa deletion. In a lexical decision experiment it was investigated whether the phonological variants were processed similarly to the standard forms. It was found that the two types of variation patterned differently. Words with schwa epenthesis were processed faster and more accurately than the standard forms, whereas words with schwa deletion led to less fast and less accurate responses. The results are discussed in relation to the role of consonant-vowel alternations in speech processing and the perceptual integrity of onset clusters.
  • Küntay, A. C., & Slobin, D. I. (2002). Putting interaction back into child language: Examples from Turkish. Psychology of Language and Communication, 6(1): 14.

    Abstract

    As in the case of other non-English languages, the study of the acquisition of Turkish has mostly focused on aspects of grammatical morphology and syntax, largely neglecting the study of the effect of interactional factors on child morphosyntax. This paper reviews indications from past research that studying input and adult-child discourse can facilitate the study of the acquisition of morphosyntax in the Turkish language. It also provides some recent studies of Turkish child language on the relationship of child-directed speech to the early acquisition of morphosyntax, and on the pragmatic features of a certain kind of discourse form in child-directed speech called variation sets.
  • Kuntay, A., & Ozyurek, A. (2002). Joint attention and the development of the use of demonstrative pronouns in Turkish. In B. Skarabela, S. Fish, & A. H. Do (Eds.), Proceedings of the 26th annual Boston University Conference on Language Development (pp. 336-347). Somerville, MA: Cascadilla Press.
  • Kuzla, C., & Ernestus, M. (2011). Prosodic conditioning of phonetic detail in German plosives. Journal of Phonetics, 39, 143-155. doi:10.1016/j.wocn.2011.01.001.

    Abstract

    This study investigates the prosodic conditioning of phonetic details which are candidate cues to phonological contrasts. German /b, d, g, p, t, k/ were examined in three prosodic positions. Lenis plosives /b, d, g/ were produced with less glottal vibration at larger prosodic boundaries, whereas their VOT showed no effect of prosody. VOT of fortis plosives /p, t, k/ decreased at larger boundaries, as did their burst intensity maximum. Vowels (when measured from consonantal release) following fortis plosives and lenis velars were shorter after larger boundaries. Closure duration, which did not contribute to the fortis/lenis contrast, was heavily affected by prosody. These results support neither of the hitherto proposed accounts of prosodic strengthening (Uniform Strengthening and Feature Enhancement). We propose a different account, stating that the phonological identity of speech sounds remains stable not only within, but also across prosodic positions (contrast-over-prosody hypothesis). Domain-initial strengthening hardly diminishes the contrast between prosodically weak fortis and strong lenis plosives.
  • Laaksonen, H., Kujala, J., Hultén, A., Liljeström, M., & Salmelin, R. (2011). MEG evoked responses and rhythmic activity provide spatiotemporally complementary measures of neural activity in language production. NeuroImage, 60, 29-36. doi:MEG evoked responses and rhythmic activity provide spatiotemporally complementary measures of neural activity in language production.

    Abstract

    Phase-locked evoked responses and event-related modulations of spontaneous rhythmic activity are the two main approaches used to quantify stimulus- or task-related changes in electrophysiological measures. The relationship between the two has beenwidely theorized upon but empirical research has been limited to the primary visual and sensorimotor cortex. However, both evoked responses and rhythms have been used as markers of neural activity in paradigms ranging from simple sensory to complex cognitive tasks.While some spatial agreement between the two phenomena has been observed, typically only one of the measures has been used in any given study, thus disallowing a direct evaluation of their exact spatiotemporal relationship. In this study, we sought to systematically clarify the connection between evoked responses and rhythmic activity. Using both measures, we identified the spatiotemporal patterns of task effects in three magnetoencephalography (MEG) data sets, all variants of a picture naming task. Evoked responses and rhythmic modulation yielded largely separate networks, with spatial overlap mainly in the sensorimotor and primary visual areas.Moreover, in the cortical regions thatwere identified with both measures the experimental effects they conveyed differed in terms of timing and function. Our results suggest that the two phenomena are largely detached and that both measures are needed for an accurate portrayal of brain activity.
  • Lacan, M., Keyser, C., Ricaut, F.-X., Brucato, N., Duranthon, F., Guilaine, J., Crubézy, E., & Ludes, B. (2011). Ancient DNA reveals male diffusion through the Neolithic Mediterranean route. Proceedings of the National Academy of Sciences of the United States of America, 108, 9788-9791. doi:10.1073/pnas.1100723108.

    Abstract

    The Neolithic is a key period in the history of the European settlement. Although archaeological and present-day genetic data suggest several hypotheses regarding the human migration patterns at this period, validation of these hypotheses with the use of ancient genetic data has been limited. In this context, we studied DNA extracted from 53 individuals buried in a necropolis used by a French local community 5,000 y ago. The relatively good DNA preservation of the samples allowed us to obtain autosomal, Y-chromosomal, and/or mtDNA data for 29 of the 53 samples studied. From these datasets, we established close parental relationships within the necropolis and determined maternal and paternal lineages as well as the absence of an allele associated with lactase persistence, probably carried by Neolithic cultures of central Europe. Our study provides an integrative view of the genetic past in southern France at the end of the Neolithic period. Furthermore, the Y-haplotype lineages characterized and the study of their current repartition in European populations confirm a greater influence of the Mediterranean than the Central European route in the peopling of southern Europe during the Neolithic transition.
  • Lacan, M., Keyser, C., Ricaut, F.-X., Brucato, N., Tarrús, J., Bosch, A., Guilaine, J., Crubézy, E., & Ludes, B. (2011). Ancient DNA suggests the leading role played by men in the Neolithic dissemination. Proceedings of the National Academy of Sciences of the United States of America, 108, 18255-18259. doi:10.1073/pnas.1113061108.

    Abstract

    The impact of the Neolithic dispersal on the western European populations is subject to continuing debate. To trace and date genetic lineages potentially brought during this transition and so understand the origin of the gene pool of current populations, we studied DNA extracted from human remains excavated in a Spanish funeral cave dating from the beginning of the fifth millennium B.C. Thanks to a “multimarkers” approach based on the analysis of mitochondrial and nuclear DNA (autosomes and Y-chromosome), we obtained information on the early Neolithic funeral practices and on the biogeographical origin of the inhumed individuals. No close kinship was detected. Maternal haplogroups found are consistent with pre-Neolithic settlement, whereas the Y-chromosomal analyses permitted confirmation of the existence in Spain approximately 7,000 y ago of two haplogroups previously associated with the Neolithic transition: G2a and E1b1b1a1b. These results are highly consistent with those previously found in Neolithic individuals from French Late Neolithic individuals, indicating a surprising temporal genetic homogeneity in these groups. The high frequency of G2a in Neolithic samples in western Europe could suggest, furthermore, that the role of men during Neolithic dispersal could be greater than currently estimated.

    Additional information

    Supporting_Information_Lacan.pdf
  • Lai, V. T., Hagoort, P., & Casasanto, D. (2011). Affective and non-affective meaning in words and pictures. In L. Carlson, C. Holscher, & T. Shipley (Eds.), Proceedings of the 33rd Annual Meeting of the Cognitive Science Society (pp. 390-395). Austin, TX: Cognitive Science Society.
  • Lai, J., & Poletiek, F. H. (2011). The impact of adjacent-dependencies and staged-input on the learnability of center-embedded hierarchical structures. Cognition, 118(2), 265-273. doi:10.1016/j.cognition.2010.11.011.

    Abstract

    A theoretical debate in artificial grammar learning (AGL) regards the learnability of hierarchical structures. Recent studies using an AnBn grammar draw conflicting conclusions (Bahlmann and Friederici, 2006, De Vries et al., 2008). We argue that 2 conditions crucially affect learning AnBn structures: sufficient exposure to zero-level-of-embedding (0-LoE) exemplars and a staged-input. In 2 AGL experiments, learning was observed only when the training set was staged and contained 0-LoE exemplars. Our results might help understanding how natural complex structures are learned from exemplars.
  • Lausberg, H., & Kita, S. (2002). Dissociation of right and left gesture spaces in split-brain patients. Cortex, 38(5), 883-886. doi:10.1016/S0010-9452(08)70062-5.

    Abstract

    The present study investigates hemispheric specialisation in the use of space in communicative gestures. For this purpose, we investigate split-brain patients in whom spontaneous and distinct right hand gestures can only be controlled by the left hemisphere and vice versa, the left hand only by the right hemisphere. On this anatomical basis, we can infer hemispheric specialisation from the performances of the right and left hands. In contrast to left hand dyspraxia in tasks that require language processing, split-brain patients utilise their left hands in a meaningful way in visuo-constructive tasks such as copying drawings or block-design. Therefore, we conjecture that split-brain patients are capable of using their left hands for the communication of the content of visuo-spatial animations via gestural demonstration. On this basis, we further examine the use of space in communicative gestures by the right and left hands. McNeill and Pedelty (1995) noted for the split-brain patient N.G. that her iconic right hand gestures were exclusively displayed in the right personal space. The present study investigates systematically if there is indication for neglect of the left personal space in right hand gestures in split-brain patients.
  • Lausberg, H., & Kita, S. (2002). Dissociation of right and left hand gesture spaces in split-brain patients. Cortex, 38(5), 883-886. doi:10.1016/S0010-9452(08)70062-5.

    Abstract

    The present study investigates hemispheric specialisation in the use of space in communicative gestures. For this purpose, we investigate split-brain patients in whom spontaneous and distinct right hand gestures can only be controlled by the left hemisphere and vice versa, the left hand only by the right hemisphere. On this anatomical basis, we can infer hemispheric specialisation from the performances of the right and left hands. In contrast to left hand dyspraxia in tasks that require language processing, split-brain patients utilise their left hands in a meaningful way in visuo-constructive tasks such as copying drawings or block-design. Therefore, we conjecture that split-brain patients are capable of using their left hands for the communication of the content of visuo-spatial animations via gestural demonstration. On this basis, we further examine the use of space in communicative gestures by the right and left hands. McNeill and Pedelty (1995) noted for the split-brain patient N.G. that her iconic right hand gestures were exclusively displayed in the right personal space. The present study investigates systematically if there is indication for neglect of the left personal space in right hand gestures in split-brain patients.
  • Leckband, D. E., Menon, S., Rosenberg, K., Graham, S. A., Taylor, M. E., & Drickamer, K. (2011). Geometry and adhesion of extracellular domains of DC-SIGNR neck length variants analyzed by force-distance measurements. Biochemistry, 50, 6125-6132. doi:10.1021/bi2003444.

    Abstract

    Force-distance measurements have been used to examine differences in the interaction of the dendritic cell glycan-binding receptor DC-SIGN and the closely related endothelial cell receptor DC-SIGNR (L-SIGN) with membranes bearing glycan ligands. The results demonstrate that upon binding to membrane-anchored ligand, DC-SIGNR undergoes a conformational change similar to that previously observed for DC-SIGN. The results also validate a model for the extracellular domain of DC-SIGNR derived from crystallographic studies. Force measurements were performed with DC-SIGNR variants that differ in the length of the neck that result from genetic polymorphisms, which encode different numbers of the 23-amino acid repeat sequences that constitute the neck. The findings are consistent with an elongated, relatively rigid structure of the neck repeat observed in crystals. In addition, differences in the lengths of DC-SIGN and DC-SIGNR extracellular domains with equivalent numbers of neck repeats support a model in which the different dispositions of the carbohydrate-recognition domains in DC-SIGN and DC-SIGNR result from variations in the sequences of the necks.
  • Lenkiewicz, P., Wittenburg, P., Schreer, O., Masneri, S., Schneider, D., & Tschöpel, S. (2011). Application of audio and video processing methods for language research. In Proceedings of the conference Supporting Digital Humanities 2011 [SDH 2011], Copenhagen, Denmark, November 17-18, 2011.

    Abstract

    Annotations of media recordings are the grounds for linguistic research. Since creating those annotations is a very laborious task, reaching 100 times longer than the length of the annotated media, innovative audio and video processing algorithms are needed, in order to improve the efficiency and quality of annotation process. The AVATecH project, started by the Max-Planck Institute for Psycholinguistics (MPI) and the Fraunhofer institutes HHI and IAIS, aims at significantly speeding up the process of creating annotations of audio-visual data for humanities research. In order for this to be achieved a range of state-of-the-art audio and video pattern recognition algorithms have been developed and integrated into widely used ELAN annotation tool. To address the problem of heterogeneous annotation tasks and recordings we provide modular components extended by adaptation and feedback mechanisms to achieve competitive annotation quality within significantly less annotation time.
  • Lenkiewicz, P., Wittenburg, P., Gebre, B. G., Lenkiewicz, A., Schreer, O., & Masneri, S. (2011). Application of video processing methods for linguistic research. In Z. Vetulani (Ed.), Human language technologies as a challenge for computer science and linguistics. Proceedings of the 5th Language and Technology Conference (LTC 2011), November 25-27, 2011, Poznań, Poland (pp. 561-564).

    Abstract

    Evolution and changes of all modern languages is a well-known fact. However, recently it is reaching dynamics never seen before, which results in loss of the vast amount of information encoded in every language. In order to preserve such heritage, properly annotated recordings of world languages are necessary. Since creating those annotations is a very laborious task, reaching times 100 longer than the length of the annotated media, innovative video processing algorithms are needed, in order to improve the efficiency and quality of annotation process.
  • Lenkiewicz, P., Pereira, M., Freire, M., & Fernandes, J. (2011). Extended whole mesh deformation model: Full 3D processing. In Proceedings of the 2011 IEEE International Conference on Image Processing (pp. 1633-1636).

    Abstract

    Processing medical data has always been an interesting field that has shown the need for effective image segmentation methods. Modern medical image segmentation solutions are focused on 3D image volumes, which originate at advanced acquisition devices. Operating on such data in a 3D envi- ronment is essential in order to take the full advantage of the available information. In this paper we present an extended version of our 3D image segmentation and reconstruction model that belongs to the family of Deformable Models and is capable of processing large image volumes in competitive times and in fully 3D environment, offering a big level of automation of the process and a high precision of results. It is also capable of handling topology changes and offers a very good scalability on multi-processing unit architectures. We present a description of the model and show its capabilities in the field of medical image processing.
  • Levelt, W. J. M. (2002). Picture naming and word frequency: Comments on Alario, Costa and Caramazza, Language and Cognitive Processes, 17(3), 299-319. Language and Cognitive Processes, 17(6), 663-671. doi:0.1080/01690960143000443.

    Abstract

    This commentary on Alario et al. (2002) addresses two issues: (1) Different from what the authors suggest, there are no theories of production claiming the phonological word to be the upper bound of advance planning before the onset of articulation; (2) Their picture naming study of word frequency effects on speech onset is inconclusive by lack of a crucial control, viz., of object recognition latency. This is a perennial problem in picture naming studies of word frequency and age of acquisition effects
  • Levelt, W. J. M. (1996). Hoedt u voor neurolinguïstisch programmeren. Actieblad tegen de kwakzalverij, 107, 12-14.
  • Levelt, W. J. M. (1996). Waar komen gesproken woorden vandaan? De Psycholoog, 31, 434-437.
  • Levinson, S. C., Kita, S., Haun, D. B. M., & Rasch, B. H. (2002). Returning the tables: Language affects spatial reasoning. Cognition, 84(2), 155-188. doi:10.1016/S0010-0277(02)00045-8.

    Abstract

    Li and Gleitman (Turning the tables: language and spatial reasoning. Cognition, in press) seek to undermine a large-scale cross-cultural comparison of spatial language and cognition which claims to have demonstrated that language and conceptual coding in the spatial domain covary (see, for example, Space in language and cognition: explorations in linguistic diversity. Cambridge: Cambridge University Press, in press; Language 74 (1998) 557): the most plausible interpretation is that different languages induce distinct conceptual codings. Arguing against this, Li and Gleitman attempt to show that in an American student population they can obtain any of the relevant conceptual codings just by varying spatial cues, holding language constant. They then argue that our findings are better interpreted in terms of ecologically-induced distinct cognitive styles reflected in language. Linguistic coding, they argue, has no causal effects on non-linguistic thinking – it simply reflects antecedently existing conceptual distinctions. We here show that Li and Gleitman did not make a crucial distinction between frames of spatial reference relevant to our line of research. We report a series of experiments designed to show that they have, as a consequence, misinterpreted the results of their own experiments, which are in fact in line with our hypothesis. Their attempts to reinterpret the large cross-cultural study, and to enlist support from animal and infant studies, fail for the same reasons. We further try to discern exactly what theory drives their presumption that language can have no cognitive efficacy, and conclude that their position is undermined by a wide range of considerations.
  • Levinson, S. C. (2002). Time for a linguistic anthropology of time. Current Anthropology, 43(4), S122-S123. doi:10.1086/342214.
  • Levinson, S. C. (1996). Language and space. Annual Review of Anthropology, 25, 353-382. doi:10.1146/annurev.anthro.25.1.353.

    Abstract

    This review describes some recent, unexpected findings concerning variation in spatial language across cultures, and places them in the context of the general anthropology of space on the one hand, and theories of spatial cognition in the cognitive sciences on the other. There has been much concern with the symbolism of space in anthropological writings, but little on concepts of space in practical activities. This neglect of everyday spatial notions may be due to unwitting ethnocentrism, the assumption in Western thinking generally that notions of space are universally of a single kind. Recent work shows that systems of spatial reckoning and description can in fact be quite divergent across cultures, linguistic differences correlating with distinct cognitive tendencies. This unexpected cultural variation raises interesting questions concerning the relation between cultural and linguistic concepts and the biological foundations of cognition. It argues for more sophisticated models relating culture and cognition than we currently have available.
  • Levinson, S. C. (2011). Pojmowanie przestrzeni w różnych kulturach [Polish translation of Levinson, S. C. 1998. Studying spatial conceptualization across cultures]. Autoportret, 33, 16-23.

    Abstract

    Polish translation of Levinson, S. C. (1998). Studying spatial conceptualization across cultures: Anthropology and cognitive science. Ethos, 26(1), 7-24. doi:10.1525/eth.1998.26.1.7
  • Levinson, S. C., Greenhill, S. J., Gray, R. D., & Dunn, M. (2011). Universal typological dependencies should be detectable in the history of language families. Linguistic Typology, 15, 509-534. doi:10.1515/LITY.2011.034.

    Abstract

    1. Introduction We claim that making sense of the typological diversity of languages demands a historical/evolutionary approach.We are pleased that the target paper (Dunn et al. 2011a) has served to bring discussion of this claim into prominence, and are grateful that leading typologists have taken the time to respond (commentaries denoted by boldface). It is unfortunate though that a number of the commentaries in this issue of LT show significant misunderstandings of our paper. Donohue thinks we were out to show the stability of typological features, but that was not our target at all (although related methods can be used to do that: see, e.g., Greenhill et al. 2010a, Dediu 2011a). Plank seems to think we were arguing against universals of any type, but our target was in fact just the implicational universals of word order that have been the bread and butter of typology. He also seems to think we ignore diachrony, whereas in fact the method introduces diachrony centrally into typological reasoning, thereby potentially revolutionising typology (see Cysouw’s commentary). Levy & Daumé think we were testing for lineage-specificity, whereas that was in fact an outcome (the main finding) of our testing for correlated evolution. Dryer thinks we must account for the distribution of language types around the world, but that was not our aim: our aim was to test the causal connection between linguistic variables by taking the perspective of language evolution (diversification and change). Longobardi & Roberts seem to think we set out to extract family trees from syntactic features, but our goal was in fact to use trees based on lexical cognates and hang reconstructed syntactic states on each node of these trees, thereby reconstructing the processes of language change.
  • Lindell, A. K., & Kidd, E. (2011). Why right-brain teaching is half-witted: A critique of the misapplication of neuroscience to education. Mind, Brain and Education, 5(3), 121-127. doi:10.1111/j.1751-228X.2011.01120.x.

    Abstract

    Educational tools claiming to use “right-brain techniques” are increasingly shaping school curricula. By implying a strong scientific basis, such approaches appeal to educators who rightly believe that knowledge of the brain should guide curriculum development. However, the notion of hemisphericity (idea that people are “left-brained” or “right-brained”) is a neuromyth that was debunked in the scientific literature 25 years ago. This article challenges the validity of “right-brain” teaching, highlighting the fact that neuroscientific research does not support its claims. Providing teachers with a basic understanding of neuroscience research as part of teacher training would enable more effective evaluation of brain-based claims and facilitate the adoption of tools validated by rigorous independent research rather than programs based on pseudoscience.
  • Liszkowski, U., & Tomasello, M. (2011). Individual differences in social, cognitive, and morphological aspects of infant pointing. Cognitive Development, 26, 16-29. doi:10.1016/j.cogdev.2010.10.001.

    Abstract

    Little is known about the origins of the pointing gesture. We sought to gain insight into its emergence by investigating individual differences in the pointing of 12-month-old infants in two ways. First, we looked at differences in the communicative and interactional uses of pointing and asked how different hand shapes relate to point frequency, accompanying vocalizations, and mothers’ pointing. Second, we looked at differences in social-cognitive skills of point comprehension and imitation and tested whether these were related to infants’ own pointing. Infants’ and mothers’ spontaneous pointing correlated with one another, as did infants’ point production and comprehension. In particular, infants’ index-finger pointing had a profile different from simple whole-hand pointing. It was more frequent, it was more often accompanied by vocalizations, and it correlated more strongly with comprehension of pointing (especially to occluded referents). We conclude that whole-hand and index-finger pointing differ qualitatively and suggest that it is index-finger pointing that first embodies infants’ understanding of communicative intentions.
  • Liszkowski, U. (2011). Three lines in the emergence of prelinguistic communication and social cognition. Journal of cognitive education and psychology, 10(1), 32-43. doi:10.1891/1945-8959.10.1.32.

    Abstract

    Sociocultural theories of development posit that higher cognitive functions emerge through socially mediated processes, in particular through language. However, theories of human communication posit that language itself is based on higher social cognitive skills and cooperative motivations. Prelinguistic communication is a test case to this puzzle. In the current review, I first present recent and new findings of a research program on prelinguistic infants’ ommunication skills. This research provides empirical evidence for a rich social cognitive and motivational basis of human communication before language. Next, I discuss the emergence of these foundational skills. By considering all three lines of development, and by drawing on new findings from phylogenetic and cross-cultural comparisons, this article discusses the possibility that the cognitive foundations of prelinguistic communication are, in turn, mediated by social interactional input and shared experiences.
  • Lloyd, S. E., Pearce, S. H. S., Fisher, S. E., Steinmeyer, K., Schwappach, B., Scheinman, S. J., Harding, B., Bolino, A., Devoto, M., Goodyer, P., Rigden, S. P. A., Wrong, O., Jentsch, T. J., Craig, I. W., & Thakker, R. V. (1996). A common molecular basis for three inherited kidney stone diseases [Letter to Nature]. Nature, 379, 445 -449. doi:10.1038/379445a0.

    Abstract

    Kidney stones (nephrolithiasis), which affect 12% of males and 5% of females in the western world, are familial in 45% of patients and are most commonly associated with hypercalciuria. Three disorders of hypercalciuric nephrolithiasis (Dent's disease, X-linked recessive nephrolithiasis (XRN), and X-linked recessive hypophosphataemic rickets (XLRH)) have been mapped to Xp11.22 (refs 5-7). A microdeletion in one Dent's disease kindred allowed the identification of a candidate gene, CLCN5 (refs 8,9) which encodes a putative renal chloride channel. Here we report the investigation of 11 kindreds with these renal tubular disorders for CLCN5 abnormalities; this identified three nonsense, four missense and two donor splice site mutations, together with one intragenic deletion and one microdeletion encompassing the entire gene. Heterologous expression of wild-type CLCN5 in Xenopus oocytes yielded outwardly rectifying chloride currents, which were either abolished or markedly reduced by the mutations. The common aetiology for Dent's disease, XRN and XLRH indicates that CLCN5 may be involved in other renal tubular disorders associated with kidney stones
  • Mace, R., & Jordan, F. (2011). Macro-evolutionary studies of cultural diversity: A review of empirical studies of cultural transmission and cultural adaptation. Philosophical Transactions of the Royal Society of London B, Biological Sciences, 366, 402-411. doi:10.1098/rstb.2010.0238.

    Abstract

    A growing body of theoretical and empirical research has examined cultural transmission and adaptive cultural behaviour at the individual, within-group level. However, relatively few studies have tried to examine proximate transmission or test ultimate adaptive hypotheses about behavioural or cultural diversity at a between-societies macro-level. In both the history of anthropology and in present-day work, a common approach to examining adaptive behaviour at the macro-level has been through correlating various cultural traits with features of ecology. We discuss some difficulties with simple ecological associations, and then review cultural phylogenetic studies that have attempted to go beyond correlations to understand the underlying cultural evolutionary processes. We conclude with an example of a phylogenetically controlled approach to understanding proximate transmission pathways in Austronesian cultural diversity.
  • Maess, B., Friederici, A. D., Damian, M., Meyer, A. S., & Levelt, W. J. M. (2002). Semantic category interference in overt picture naming: Sharpening current density localization by PCA. Journal of Cognitive Neuroscience, 14(3), 455-462. doi:10.1162/089892902317361967.

    Abstract

    The study investigated the neuronal basis of the retrieval of words from the mental lexicon. The semantic category interference effect was used to locate lexical retrieval processes in time and space. This effect reflects the finding that, for overt naming, volunteers are slower when naming pictures out of a sequence of items from the same semantic category than from different categories. Participants named pictures blockwise either in the context of same- or mixedcategory items while the brain response was registered using magnetoencephalography (MEG). Fifteen out of 20 participants showed longer response latencies in the same-category compared to the mixed-category condition. Event-related MEG signals for the participants demonstrating the interference effect were submitted to a current source density (CSD) analysis. As a new approach, a principal component analysis was applied to decompose the grand average CSD distribution into spatial subcomponents (factors). The spatial factor indicating left temporal activity revealed significantly different activation for the same-category compared to the mixedcategory condition in the time window between 150 and 225 msec post picture onset. These findings indicate a major involvement of the left temporal cortex in the semantic interference effect. As this effect has been shown to take place at the level of lexical selection, the data suggest that the left temporal cortex supports processes of lexical retrieval during production.
  • Majid, A. (2002). Frames of reference and language concepts. Trends in Cognitive Sciences, 6(12), 503-504. doi:10.1016/S1364-6613(02)02024-7.
  • Majid, A., & Levinson, S. C. (Eds.). (2011). The senses in language and culture [Special Issue]. The Senses & Society, 6(1).
  • Majid, A., & Levinson, S. C. (2011). The senses in language and culture. The Senses & Society, 6(1), 5-18. doi:10.2752/174589311X12893982233551.

    Abstract

    Multiple social science disciplines have converged on the senses in recent years, where formerly the domain of perception was the preserve of psychology. Linguistics, or Language, however, seems to have an ambivalent role in this undertaking. On the one hand, Language with a capital L (language as a general human capacity) is part of the problem. It was the prior focus on language (text) that led to the disregard of the senses. On the other hand, it is language (with a small "l", a particular tongue) that offers key insights into how other peoples onceptualize the senses. In this article, we argue that a systematic cross-cultural approach can reveal fundamental truths about the precise connections between language and the senses. Recurring failures to adequately describe the sensorium across specific languages reveal the intrinsic limits of Language. But the converse does not hold. Failures of expressibility in one language need not hold any implications for the Language faculty per se, and indeed can enlighten us about the possible experiential worlds available to human experience.
  • Majid, A., Evans, N., Gaby, A., & Levinson, S. C. (2011). The grammar of exchange: A comparative study of reciprocal constructions across languages. Frontiers in Psychology, 2: 34, pp. 34. doi:10.3389/fpsyg.2011.00034.

    Abstract

    Cultures are built on social exchange. Most languages have dedicated grammatical machinery for expressing this. To demonstrate that statistical methods can also be applied to grammatical meaning, we here ask whether the underlying meanings of these grammatical constructions are based on shared common concepts. To explore this, we designed video stimuli of reciprocated actions (e.g. ‘giving to each other’) and symmetrical states (e.g. ‘sitting next to each other’), and with the help of a team of linguists collected responses from 20 languages around the world. Statistical analyses revealed that many languages do, in fact, share a common conceptual core for reciprocal meanings but that this is not a universally expressed concept. The recurrent pattern of conceptual packaging found across languages is compatible with the view that there is a shared non-linguistic understanding of reciprocation. But, nevertheless, there are considerable differences between languages in the exact extensional patterns, highlighting that even in the domain of grammar semantics is highly language-specific.
  • Majid, A., & Levinson, S. C. (2011). The language of perception across cultures [Abstract]. Abstracts of the XXth Congress of European Chemoreception Research Organization, ECRO-2010. Publ. in Chemical Senses, 36(1), E7-E8.

    Abstract

    How are the senses structured by the languages we speak, the cultures we inhabit? To what extent is the encoding of perceptual experiences in languages a matter of how the mind/brain is ―wired-up‖ and to what extent is it a question of local cultural preoccupation? The ―Language of Perception‖ project tests the hypothesis that some perceptual domains may be more ―ineffable‖ – i.e. difficult or impossible to put into words – than others. While cognitive scientists have assumed that proximate senses (olfaction, taste, touch) are more ineffable than distal senses (vision, hearing), anthropologists have illustrated the exquisite variation and elaboration the senses achieve in different cultural milieus. The project is designed to test whether the proximate senses are universally ineffable – suggesting an architectural constraint on cognition – or whether they are just accidentally so in Indo-European languages, so expanding the role of cultural interests and preoccupations. To address this question, a standardized set of stimuli of color patches, geometric shapes, simple sounds, tactile textures, smells and tastes have been used to elicit descriptions from speakers of more than twenty languages—including three sign languages. The languages are typologically, genetically and geographically diverse, representing a wide-range of cultures. The communities sampled vary in subsistence modes (hunter-gatherer to industrial), ecological zones (rainforest jungle to desert), dwelling types (rural and urban), and various other parameters. We examine how codable the different sensory modalities are by comparing how consistent speakers are in how they describe the materials in each modality. Our current analyses suggest that taste may, in fact, be the most codable sensorial domain across languages. Moreover, we have identified exquisite elaboration in the olfactory domains in some cultural settings, contrary to some contemporary predictions within the cognitive sciences. These results suggest that differential codability may be at least partly the result of cultural preoccupation. This shows that the senses are not just physiological phenomena but are constructed through linguistic, cultural and social practices.
  • Mak, W. M., Vonk, W., & Schriefers, H. (2002). The influence of animacy on relative clause processing. Journal of Memory and Language, 47(1), 50-68. doi:10.1006/jmla.2001.2837.

    Abstract

    In previous research it has been shown that subject relative clauses are easier to process than object relative clauses. Several theories have been proposed that explain the difference on the basis of different theoretical perspectives. However, previous research tested relative clauses only with animate protagonists. In a corpus study of Dutch and German newspaper texts, we show that animacy is an important determinant of the distribution of subject and object relative clauses. In two experiments in Dutch, in which the animacy of the object of the relative clause is varied, no difference in reading time is obtained between subject and object relative clauses when the object is inanimate. The experiments show that animacy influences the processing difficulty of relative clauses. These results can only be accounted for by current major theories of relative clause processing when additional assumptions are introduced, and at the same time show that the possibility of semantically driven analysis can be considered as a serious alternative.
  • Malt, B. C., Ameel, E., Gennari, S., Imai, M., Saji, N., & Majid, A. (2011). Do words reveal concepts? In L. Carlson, C. Hölscher, & T. Shipley (Eds.), Proceedings of the 33rd Annual Conference of the Cognitive Science Society (pp. 519-524). Austin, TX: Cognitive Science Society.

    Abstract

    To study concepts, cognitive scientists must first identify some. The prevailing assumption is that they are revealed by words such as triangle, table, and robin. But languages vary dramatically in how they carve up the world by name. Either ordinary concepts must be heavily language-dependent or names cannot be a direct route to concepts. We asked English, Dutch, Spanish, and Japanese speakers to name videos of human locomotion and judge their similarities. We investigated what name inventories and scaling solutions on name similarity and on physical similarity for the groups individually and together suggest about the underlying concepts. Aggregated naming and similarity solutions converged on results distinct from the answers suggested by the word inventories and scaling solutions of any single language. Words such as triangle, table, and robin can help identify the conceptual space of a domain, but they do not directly reveal units of knowledge usefully considered 'concepts'.
  • Marlow, A. J., Fisher, S. E., Richardson, A. J., Francks, C., Talcott, J. B., Monaco, A. P., Stein, J. F., & Cardon, L. R. (2002). Investigation of quantitative measures related to reading disability in a large sample of sib-pairs from the UK. Behavior Genetics, 31(2), 219-230. doi:10.1023/A:1010209629021.

    Abstract

    We describe a family-based sample of individuals with reading disability collected as part of a quantitative trait loci (QTL) mapping study. Eighty-nine nuclear families (135 independent sib-pairs) were identified through a single proband using a traditional discrepancy score of predicted/actual reading ability and a known family history. Eight correlated psychometric measures were administered to each sibling, including single word reading, spelling, similarities, matrices, spoonerisms, nonword and irregular word reading, and a pseudohomophone test. Summary statistics for each measure showed a reduced mean for the probands compared to the co-sibs, which in turn was lower than that of the population. This partial co-sib regression back to the mean indicates that the measures are influenced by familial factors and therefore, may be suitable for a mapping study. The variance of each of the measures remained largely unaffected, which is reassuring for the application of a QTL approach. Multivariate genetic analysis carried out to explore the relationship between the measures identified a common factor between the reading measures that accounted for 54% of the variance. Finally the familiality estimates (range 0.32–0.73) obtained for the reading measures including the common factor (0.68) supported their heritability. These findings demonstrate the viability of this sample for QTL mapping, and will assist in the interpretation of any subsequent linkage findings in an ongoing genome scan.
  • de Marneffe, M.-C., Tomlinson, J. J., Tice, M., & Sumner, M. (2011). The interaction of lexical frequency and phonetic variation in the perception of accented speech. In L. Carlson, C. Hölscher, & T. Shipley (Eds.), Proceedings of the 33rd Annual Conference of the Cognitive Science Society (pp. 3575-3580). Austin, TX: Cognitive Science Society.

    Abstract

    How listeners understand spoken words despite massive variation in the speech signal is a central issue for linguistic theory. A recent focus on lexical frequency and specificity has proved fruitful in accounting for this phenomenon. Speech perception, though, is a multi-faceted process and likely incorporates a number of mechanisms to map a variable signal to meaning. We examine a well-established language use factor — lexical frequency — and how this factor is integrated with phonetic variability during the perception of accented speech. We show that an integrated perspective highlights a low-level perceptual mechanism that accounts for the perception of accented speech absent native contrasts, while shedding light on the use of interactive language factors in the perception of spoken words.
  • Martin, A. E., & McElree, B. (2011). Direct-access retrieval during sentence comprehension: Evidence from Sluicing. Journal of Memory and Language, 64(4), 327-343. doi:10.1016/j.jml.2010.12.006.

    Abstract

    Language comprehension requires recovering meaning from linguistic form, even when the mapping between the two is indirect. A canonical example is ellipsis, the omission of information that is subsequently understood without being overtly pronounced. Comprehension of ellipsis requires retrieval of an antecedent from memory, without prior prediction, a property which enables the study of retrieval in situ ( Martin and McElree, 2008 and Martin and McElree, 2009). Sluicing, or inflectional-phrase ellipsis, in the presence of a conjunction, presents a test case where a competing antecedent position is syntactically licensed, in contrast with most cases of nonadjacent dependency, including verb–phrase ellipsis. We present speed–accuracy tradeoff and eye-movement data inconsistent with the hypothesis that retrieval is accomplished via a syntactically guided search, a particular variant of search not examined in past research. The observed timecourse profiles are consistent with the hypothesis that antecedents are retrieved via a cue-dependent direct-access mechanism susceptible to general memory variables.
  • Matsuo, A., & Duffield, N. (2002). Assessing the generality of knowledge about English ellipsis in SLA. In J. Costa, & M. J. Freitas (Eds.), Proceedings of the GALA 2001 Conference on Language Acquisition (pp. 49-53). Lisboa: Associacao Portuguesa de Linguistica.
  • Matsuo, A., & Duffield, N. (2002). Finiteness and parallelism: Assessing the generality of knowledge about English ellipsis in SLA. In B. Skarabela, S. Fish, & A.-H.-J. Do (Eds.), Proceedings of the 26th Boston University Conference on Language Development (pp. 197-207). Somerville, Massachusetts: Cascadilla Press.
  • Matthews, L. J., Tehrani, J. J., Jordan, F., Collard, M., & Nunn, C. (2011). Testing for divergent transmission histories among cultural characters: A study using Bayesian phylogenetic methods and Iranian tribal textile data. Plos One, 6(4), e14810. doi:10.1371/journal.pone.0014810.

    Abstract

    Abstract Background: Archaeologists and anthropologists have long recognized that different cultural complexes may have distinct descent histories, but they have lacked analytical techniques capable of easily identifying such incongruence. Here, we show how Bayesian phylogenetic analysis can be used to identify incongruent cultural histories. We employ the approach to investigate Iranian tribal textile traditions. Methods: We used Bayes factor comparisons in a phylogenetic framework to test two models of cultural evolution: the hierarchically integrated system hypothesis and the multiple coherent units hypothesis. In the hierarchically integrated system hypothesis, a core tradition of characters evolves through descent with modification and characters peripheral to the core are exchanged among contemporaneous populations. In the multiple coherent units hypothesis, a core tradition does not exist. Rather, there are several cultural units consisting of sets of characters that have different histories of descent. Results: For the Iranian textiles, the Bayesian phylogenetic analyses supported the multiple coherent units hypothesis over the hierarchically integrated system hypothesis. Our analyses suggest that pile-weave designs represent a distinct cultural unit that has a different phylogenetic history compared to other textile characters. Conclusions: The results from the Iranian textiles are consistent with the available ethnographic evidence, which suggests that the commercial rug market has influenced pile-rug designs but not the techniques or designs incorporated in the other textiles produced by the tribes. We anticipate that Bayesian phylogenetic tests for inferring cultural units will be of great value for researchers interested in studying the evolution of cultural traits including language, behavior, and material culture.
  • Mauner, G., Melinger, A., Koenig, J.-P., & Bienvenue, B. (2002). When is schematic participant information encoded: Evidence from eye-monitoring. Journal of Memory and Language, 47(3), 386-406. doi:10.1016/S0749-596X(02)00009-8.

    Abstract

    Two eye-monitoring studies examined when unexpressed schematic participant information specified by verbs is used during sentence processing. Experiment 1 compared the processing of sentences with passive and intransitive verbs hypothesized to introduce or not introduce, respectively, an agent when their main clauses were preceded by either agent-dependent rationale clauses or adverbial clause controls. While there were no differences in the processing of passive clauses following rationale and control clauses, intransitive verb clauses elicited anomaly effects following agent-dependent rationale clauses. To determine whether the source of this immediately available schematic participant information is lexically specified or instead derived solely from conceptual sources associated with verbs, Experiment 2 compared the processing of clauses with passive and middle verbs following rationale clauses (e.g., To raise money for the charity, the vase was/had sold quickly…). Although both passive and middle verb forms denote situations that logically require an agent, middle verbs, which by hypothesis do not lexically specify an agent, elicited longer processing times than passive verbs in measures of early processing. These results demonstrate that participants access and interpret lexically encoded schematic participant information in the process of recognizing a verb.
  • McGettigan, C., Warren, J. E., Eisner, F., Marshall, C. R., Shanmugalingam, P., & Scott, S. K. (2011). Neural correlates of sublexical processing in phonological working memory. Journal of Cognitive Neuroscience, 23, 961-977. doi:10.1162/jocn.2010.21491.

    Abstract

    This study investigated links between working memory and speech processing systems. We used delayed pseudoword repetition in fMRI to investigate the neural correlates of sublexical structure in phonological working memory (pWM). We orthogonally varied the number of syllables and consonant clusters in auditory pseudowords and measured the neural responses to these manipulations under conditions of covert rehearsal (Experiment 1). A left-dominant network of temporal and motor cortex showed increased activity for longer items, with motor cortex only showing greater activity concomitant with adding consonant clusters. An individual-differences analysis revealed a significant positive relationship between activity in the angular gyrus and the hippocampus, and accuracy on pseudoword repetition. As models of pWM stipulate that its neural correlates should be activated during both perception and production/rehearsal [Buchsbaum, B. R., & D'Esposito, M. The search for the phonological store: From loop to convolution. Journal of Cognitive Neuroscience, 20, 762-778, 2008; Jacquemot, C., & Scott, S. K. What is the relationship between phonological short-term memory and speech processing? Trends in Cognitive Sciences, 10, 480-486, 2006; Baddeley, A. D., & Hitch, G. Working memory. In G. H. Bower (Ed.), The psychology of learning and motivation: Advances in research and theory (Vol. 8, pp. 47-89). New York: Academic Press, 1974], we further assessed the effects of the two factors in a separate passive listening experiment (Experiment 2). In this experiment, the effect of the number of syllables was concentrated in posterior-medial regions of the supratemporal plane bilaterally, although there was no evidence of a significant response to added clusters. Taken together, the results identify the planum temporale as a key region in pWM; within this region, representations are likely to take the form of auditory or audiomotor -templates- or -chunks- at the level of the syllable [Papoutsi, M., de Zwart, J. A., Jansma, J. M., Pickering, M. J., Bednar, J. A., & Horwitz, B. From phonemes to articulatory codes: an fMRI study of the role of Broca's area in speech production. Cerebral Cortex, 19, 2156-2165, 2009; Warren, J. E., Wise, R. J. S., & Warren, J. D. Sounds do-able: auditory-motor transformations and the posterior temporal plane. Trends in Neurosciences, 28, 636-643, 2005; Griffiths, T. D., & Warren, J. D. The planum temporale as a computational hub. Trends in Neurosciences, 25, 348-353, 2002], whereas more lateral structures on the STG may deal with phonetic analysis of the auditory input [Hickok, G. The functional neuroanatomy of language. Physics of Life Reviews, 6, 121-143, 2009].
  • Melinger, A. (2002). Foot structure and accent in Seneca. International Journal of American Linguistics, 68(3), 287-315.

    Abstract

    Argues that the Seneca accent system can be explained more simply and naturally if the foot structure is reanalyzed as trochaic. Determination of the position of the accent by the position and structure of the accented syllable and by the position and structure of the post-tonic syllable; Assignment of the pair of syllables which interact to predict where accent is assigned in different iambic feet.
  • Menenti, L., Gierhan, S., Segaert, K., & Hagoort, P. (2011). Shared language: Overlap and segregation of the neuronal infrastructure for speaking and listening revealed by functional MRI. Psychological Science, 22, 1173-1182. doi:10.1177/0956797611418347.

    Abstract

    Whether the brain’s speech-production system is also involved in speech comprehension is a topic of much debate. Research has focused on whether motor areas are involved in listening, but overlap between speaking and listening might occur not only at primary sensory and motor levels, but also at linguistic levels (where semantic, lexical, and syntactic processes occur). Using functional MRI adaptation during speech comprehension and production, we found that the brain areas involved in semantic, lexical, and syntactic processing are mostly the same for speaking and for listening. Effects of primary processing load (indicative of sensory and motor processes) overlapped in auditory cortex and left inferior frontal cortex, but not in motor cortex, where processing load affected activity only in speaking. These results indicate that the linguistic parts of the language system are used for both speaking and listening, but that the motor system does not seem to provide a crucial contribution to listening.
  • Mester, J. L., Tilot, A. K., Rybicki, L. A., Frazier, T. W., & Eng, C. (2011). Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model. European Journal of Human Genetics, 19(7), 763-768. doi:10.1038/ejhg.2011.20.

    Abstract

    PTEN Hamartoma Tumour Syndrome (PHTS) includes Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome (BRRS), and other conditions resulting from germline mutation of the PTEN tumour suppressor gene. Although macrocephaly, presumably due to megencephaly, is found in both CS and BRRS, the prevalence and degree have not been formally assessed in PHTS. We evaluated head size in a prospective nested series of 181 patients found to have pathogenic germline PTEN mutations. Clinical data including occipital-frontal circumference (OFC) measurement were requested for all participants. Macrocephaly was present in 94% of 161 evaluable PHTS individuals. In patients ≤18 years, mean OFC was +4.89 standard deviations (SD) above the population mean with no difference between genders (P=0.7). Among patients >18 years, average OFC was 60.0 cm in females and 62.8 cm in males (P<0.0001). To systematically determine whether macrocephaly was due to megencephaly, we examined PtenM3M4 missense mutant mice generated and maintained on mixed backgrounds. Mice were killed at various ages, brains were dissected out and weighed. Average brain weight for PtenM3M4 homozygous mice (N=15) was 1.02 g compared with 0.57 g for heterozygous mice (N=29) and 0.49 g for wild-type littermates (N=24) (P<0.0001). Macrocephaly, secondary to megencephaly, is an important component of PHTS and more prevalent than previously appreciated. Patients with PHTS have increased risks for breast and thyroid cancers, and early diagnosis is key to initiating timely screening to reduce patient morbidity and mortality. Clinicians should consider germline PTEN testing at an early point in the diagnostic work-up for patients with extreme macrocephaly.
  • Meyer, A. S., Levelt, W. J. M., & Wissink, M. T. (1996). Een modulair model van zinsproductie. Logopedie, 9(2), 21-31.

    Abstract

    In deze bijdrage wordt een modulair model van zinsproductie besproken. De planningsprocessen, die aan de productie van een zin voorafgaan, kunnen in twee hoofdcomponenten onderverdeeld worden: deconceptualisering (het bedenken van de inhoud van de uiting) en de formulering (het vastleggen van de linguïstische vorm). Het formuleringsproces bestaat weer uit twee componenten, te weten de grammatische en fonologische codering. Ook deze componenten bestaan elk weer uit een aantal subcomponenten. Dit artikel beschrijft wat de specifieke taak van iedere component is, hoe deze uitgevoerd wordt en hoe de componenten samenwerken. Tevens worden enkele belangrijke methoden van taalproductie-onderzoek besproken.
  • Meyer, A. S. (1996). Lexical access in phrase and sentence production: Results from picture-word interference experiments. Journal of Memory and Language, 35, 477-496. doi:doi:10.1006/jmla.1996.0026.

    Abstract

    Four experiments investigated the span of advance planning for phrases and short sentences. Dutch subjects were presented with pairs of objects, which they named using noun-phrase conjunctions (e.g., the translation equivalent of ''the arrow and the bag'') or sentences (''the arrow is next to the bag''). Each display was accompanied by an auditory distracter, which was related in form or meaning to the first or second noun of the utterance or unrelated to both. For sentences and phrases, the mean speech onset time was longer when the distracter was semantically related to the first or second noun and shorter when it was phonologically related to the first noun than when it was unrelated. No phonological facilitation was found for the second noun. This suggests that before utterance onset both target lemmas and the first target form were selected.
  • Minagawa-Kawai, Y., Cristia, A., Vendelin, I., Cabrol, D., & Dupoux, E. (2011). Assessing signal-driven mechanisms in neonates: Brain responses to temporally and spectrally different sounds. Frontiers in Psychology, 2, 135. doi:10.3389/fpsyg.2011.00135.

    Abstract

    Past studies have found that, in adults, the acoustic properties of sound signals (such as fast versus slow temporal features) differentially activate the left and right hemispheres, and some have hypothesized that left-lateralization for speech processing may follow from left-lateralization to rapidly changing signals. Here, we tested whether newborns’ brains show some evidence of signal-specific lateralization responses using near-infrared spectroscopy (NIRS) and auditory stimuli that elicits lateralized responses in adults, composed of segments that vary in duration and spectral diversity. We found significantly greater bilateral responses of oxygenated hemoglobin (oxy-Hb) in the temporal areas for stimuli with a minimum segment duration of 21 ms, than stimuli with a minimum segment duration of 667 ms. However, we found no evidence for hemispheric asymmetries dependent on the stimulus characteristics. We hypothesize that acoustic-based functional brain asymmetries may develop throughout early infancy, and discuss their possible relationship with brain asymmetries for language.
  • Minagawa-Kawai, Y., Cristia, A., & Dupoux, E. (2011). Cerebral lateralization and early speech acquisition: A developmental scenario. Developmental Cognitive Neuroscience, 1, 217-232. doi:10.1016/j.dcn.2011.03.005.

    Abstract

    During the past ten years, research using Near-infrared Spectroscopy (NIRS) to study the developing brain has provided groundbreaking evidence of brain functions in infants. This paper presents a theoretically oriented review of this wealth of evidence, summarizing recent NIRS data on language processing, without neglecting other neuroimaging or behavioral studies in infancy and adulthood. We review three competing classes of hypotheses (i.e. signal-driven, domain-driven, and learning biases hypotheses) regarding the causes of hemispheric specialization for speech processing. We assess the fit between each of these hypotheses and neuroimaging evidence in speech perception and show that none of the three hypotheses can account for the entire set of observations on its own. However, we argue that they provide a good fit when combined within a developmental perspective. According to our proposed scenario, lateralization for language emerges out of the interaction between pre-existing left–right biases in generic auditory processing (signal-driven hypothesis), and a left-hemisphere predominance of particular learning mechanisms (learning-biases hypothesis). As a result of this completed developmental process, the native language is represented in the left hemisphere predominantly. The integrated scenario enables to link infant and adult data, and points to many empirical avenues that need to be explored more systematically.
  • Mitterer, H., Chen, Y., & Zhou, X. (2011). Phonological abstraction in processing lexical-tone variation: Evidence from a learning paradigm. Cognitive Science, 35, 184-197. doi:10.1111/j.1551-6709.2010.01140.x.

    Abstract

    There is a growing consensus that the mental lexicon contains both abstract and word-specific acoustic information. To investigate their relative importance for word recognition, we tested to what extent perceptual learning is word specific or generalizable to other words. In an exposure phase, participants were divided into two groups; each group was semantically biased to interpret an ambiguous Mandarin tone contour as either tone1 or tone2. In a subsequent test phase, the perception of ambiguous contours was dependent on the exposure phase: Participants who heard ambiguous contours as tone1 during exposure were more likely to perceive ambiguous contours as tone1 than participants who heard ambiguous contours as tone2 during exposure. This learning effect was only slightly larger for previously encountered than for not previously encountered words. The results speak for an architecture with prelexical analysis of phonological categories to achieve both lexical access and episodic storage of exemplars.
  • Mitterer, H. (2011). Recognizing reduced forms: Different processing mechanisms for similar reductions. Journal of Phonetics, 39, 298-303. doi:10.1016/j.wocn.2010.11.009.

    Abstract

    Recognizing phonetically reduced forms is a huge challenge for spoken-word recognition. Phonetic reductions not only occur often, but also come in a variety of forms. The paper investigates how two similar forms of reductions – /t/-reduction and nasal place assimilation in Dutch – can eventually be recognized, focusing on the role of following phonological context. Previous research indicated that listeners take the following phonological context into account when compensating for /t/-reduction and nasal place assimilation. The current paper shows that these context effects arise in early perceptual processes for the perception of assimilated forms, but at a later stage of processing for the perception of /t/-reduced forms. This shows first that the recognition of apparently similarly reduced words may rely on different processing mechanisms and, second, that searching for dissociations over tasks is a promising research strategy to investigate how reduced forms are recognized.
  • Mitterer, H. (2011). Social accountability influences phonetic alignment. Journal of the Acoustical Society of America. Program abstracts of the 162nd Meeting of the Acoustical Society of America, 130(4), 2442.

    Abstract

    Speakers tend to take over the articulatory habits of their interlocutors [e.g., Pardo, JASA (2006)]. This phonetic alignment could be the consequence of either a social mechanism or a direct and automatic link between speech perception and production. The latter assumes that social variables should have little influence on phonetic alignment. To test that participants were engaged in a "cloze task" (i.e., Stimulus: "In fantasy movies, silver bullets are used to kill ..." Response: "werewolves") with either one or four interlocutors. Given findings with the Asch-conformity paradigm in social psychology, multiple consistent speakers should exert a stronger force on the participant to align. To control the speech style of the interlocutors, their questions and answers were pre-recorded in either a formal or a casual speech style. The stimuli's speech style was then manipulated between participants and was consistent throughout the experiment for a given participant. Surprisingly, participants aligned less with the speech style if there were multiple interlocutors. This may reflect a "diffusion of responsibility:" Participants may find it more important to align when they interact with only one person than with a larger group.
  • Mitterer, H. (2011). The mental lexicon is fully specified: Evidence from eye-tracking. Journal of Experimental Psychology: Human Perception and Performance, 37(2), 496-513. doi:10.1037/a0020989.

    Abstract

    Four visual-world experiments, in which listeners heard spoken words and saw printed words, compared an optimal-perception account with the theory of phonological underspecification. This theory argues that default phonological features are not specified in the mental lexicon, leading to asymmetric lexical matching: Mismatching input ("pin") activates lexical entries with underspecified coronal stops ('tin'), but lexical entries with specified labial stops ('pin') are not activated by mismatching input ("tin"). The eye-tracking data failed to show such a pattern. Although words that were phonologically similar to the spoken target attracted more looks than unrelated distractors, this effect was symmetric in Experiment 1 with minimal pairs ("tin"- "pin") and in Experiments 2 and 3 with words with an onset overlap ("peacock" - "teacake"). Experiment 4 revealed that /t/-initial words were looked at more frequently if the spoken input mismatched only in terms of place than if it mismatched in place and voice, contrary to the assumption that /t/ is unspecified for place and voice. These results show that speech perception uses signal-driven information to the fullest, as predicted by an optimal perception account.
  • Mulder, K., & Hulstijn, J. H. (2011). Linguistic skills of adult native speakers, as a function of age and level of education. Applied Linguistics, 32, 475-494. doi:10.1093/applin/amr016.

    Abstract

    This study assessed, in a sample of 98 adult native speakers of Dutch, how their lexical skills and their speaking proficiency varied as a function of their age and level of education and profession (EP). Participants, categorized in terms of their age (18–35, 36–50, and 51–76 years old) and the level of their EP (low versus high), were tested on their lexical knowledge, lexical fluency, and lexical memory, and they performed four speaking tasks, differing in genre and formality. Speaking performance was rated in terms of communicative adequacy and in terms of number of words, number of T-units, words per T-unit, content words per T-unit, hesitations per T-unit, and grammatical errors per T-unit. Increasing age affected lexical knowledge positively but lexical fluency and memory negatively. High EP positively affected lexical knowledge and memory but EP did not affect lexical fluency. Communicative adequacy of the responses in the speaking tasks was positively affected by high EP but was not affected by age. It is concluded that, given the large variability in native speakers’ language knowledge and skills, studies investigating the question of whether second-language learners can reach native levels of proficiency, should take native-speaker variability into account.

    Additional information

    Mulder_2011_Supplementary Data.doc
  • Munafò, M. R., Freathy, R. M., Ring, S. M., St Pourcain, B., & Smith, G. D. (2011). Association of COMT Val108/158Met Genotype and Cigarette Smoking in Pregnant Women. Nicotine & Tobacco Research, 13(2), 55-63. doi:10.1093/ntr/ntq209.

    Abstract

    INTRODUCTION: Smoking behaviors, including heaviness of smoking and smoking cessation, are known to be under a degree of genetic influence. The enzyme catechol O-methyltransferase (COMT) is of relevance in studies of smoking behavior and smoking cessation due to its presence in dopaminergic brain regions. While the COMT gene is therefore one of the more promising candidate genes for smoking behavior, some inconsistencies have begun to emerge. METHODS: We explored whether the rs4680 A (Met) allele of the COMT gene predicts increased heaviness of smoking and reduced likelihood of smoking cessation in a large population-based cohort of pregnant women. We further conducted a meta-analysis of published data from community samples investigating the association of this polymorphism with heaviness of smoking and smoking status. RESULTS: In our primary sample, the A (Met) allele was associated with increased heaviness of smoking before pregnancy but not with the odds of continuing to smoke in pregnancy either in the first trimester or in the third trimester. Meta-analysis also indicated modest evidence of association of the A (Met) allele with increased heaviness of smoking but not with persistent smoking. CONCLUSIONS: Our data suggest a weak association between COMT genotype and heaviness of smoking, which is supported by our meta-analysis. However, it should be noted that the strength of evidence for this association was modest. Neither our primary data nor our meta-analysis support an association between COMT genotype and smoking cessation. Therefore, COMT remains a plausible candidate gene for smoking behavior phenotypes, in particular, heaviness of smoking.

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