Publications

Displaying 2201 - 2292 of 2292
  • Watson, L. M., Wong, M. M. K., & Becker, E. B. E. (2015). Induced pluripotent stem cell technology for modelling and therapy of cerebellar ataxia. Open Biology, 5: 150056. doi:10.1098/rsob.150056.

    Abstract

    Induced pluripotent stem cell (iPSC) technology has emerged as an important tool in understanding, and potentially reversing, disease pathology. This is particularly true in the case of neurodegenerative diseases, in which the affected cell types are not readily accessible for study. Since the first descriptions of iPSC-based disease modelling, considerable advances have been made in understanding the aetiology and progression of a diverse array of neurodegenerative conditions, including Parkinson's disease and Alzheimer's disease. To date, however, relatively few studies have succeeded in using iPSCs to model the neurodegeneration observed in cerebellar ataxia. Given the distinct neurodevelopmental phenotypes associated with certain types of ataxia, iPSC-based models are likely to provide significant insights, not only into disease progression, but also to the development of early-intervention therapies. In this review, we describe the existing iPSC-based disease models of this heterogeneous group of conditions and explore the challenges associated with generating cerebellar neurons from iPSCs, which have thus far hindered the expansion of this research.
  • Weber, A., & Cutler, A. (2004). Lexical competition in non-native spoken-word recognition. Journal of Memory and Language, 50(1), 1-25. doi:10.1016/S0749-596X(03)00105-0.

    Abstract

    Four eye-tracking experiments examined lexical competition in non-native spoken-word recognition. Dutch listeners hearing English fixated longer on distractor pictures with names containing vowels that Dutch listeners are likely to confuse with vowels in a target picture name (pencil, given target panda) than on less confusable distractors (beetle, given target bottle). English listeners showed no such viewing time difference. The confusability was asymmetric: given pencil as target, panda did not distract more than distinct competitors. Distractors with Dutch names phonologically related to English target names (deksel, ‘lid,’ given target desk) also received longer fixations than distractors with phonologically unrelated names. Again, English listeners showed no differential effect. With the materials translated into Dutch, Dutch listeners showed no activation of the English words (desk, given target deksel). The results motivate two conclusions: native phonemic categories capture second-language input even when stored representations maintain a second-language distinction; and lexical competition is greater for non-native than for native listeners.
  • Weber, A., & Melinger, A. (2008). Name dominance in spoken word recognition is (not) modulated by expectations: Evidence from synonyms. In A. Botinis (Ed.), Proceedings of ISCA Tutorial and Research Workshop On Experimental Linguistics (ExLing 2008) (pp. 225-228). Athens: University of Athens.

    Abstract

    Two German eye-tracking experiments tested whether top-down expectations interact with acoustically-driven word-recognition processes. Competitor objects with two synonymous names were paired with target objects whose names shared word onsets with either the dominant or the non-dominant name of the competitor. Non-dominant names of competitor objects were either introduced before the test session or not. Eye-movements were monitored while participants heard instructions to click on target objects. Results demonstrate dominant and non-dominant competitor names were considered for recognition, regardless of top-down expectations, though dominant names were always activated more strongly.
  • Weber, A. (1998). Listening to nonnative language which violates native assimilation rules. In D. Duez (Ed.), Proceedings of the European Scientific Communication Association workshop: Sound patterns of Spontaneous Speech (pp. 101-104).

    Abstract

    Recent studies using phoneme detection tasks have shown that spoken-language processing is neither facilitated nor interfered with by optional assimilation, but is inhibited by violation of obligatory assimilation. Interpretation of these results depends on an assessment of their generality, specifically, whether they also obtain when listeners are processing nonnative language. Two separate experiments are presented in which native listeners of German and native listeners of Dutch had to detect a target fricative in legal monosyllabic Dutch nonwords. All of the nonwords were correct realisations in standard Dutch. For German listeners, however, half of the nonwords contained phoneme strings which violate the German fricative assimilation rule. Whereas the Dutch listeners showed no significant effects, German listeners detected the target fricative faster when the German fricative assimilation was violated than when no violation occurred. The results might suggest that violation of assimilation rules does not have to make processing more difficult per se.
  • Weber, A. (2000). Phonotactic and acoustic cues for word segmentation in English. In Proceedings of the 6th International Conference on Spoken Language Processing (ICSLP 2000) (pp. 782-785).

    Abstract

    This study investigates the influence of both phonotactic and acoustic cues on the segmentation of spoken English. Listeners detected embedded English words in nonsense sequences (word spotting). Words aligned with phonotactic boundaries were easier to detect than words without such alignment. Acoustic cues to boundaries could also have signaled word boundaries, especially when word onsets lacked phonotactic alignment. However, only one of several durational boundary cues showed a marginally significant correlation with response times (RTs). The results suggest that word segmentation in English is influenced primarily by phonotactic constraints and only secondarily by acoustic aspects of the speech signal.
  • Weber, A., Broersma, M., & Aoyagi, M. (2011). Spoken-word recognition in foreign-accented speech by L2 listeners. Journal of Phonetics, 39, 479-491. doi:10.1016/j.wocn.2010.12.004.

    Abstract

    Two cross-modal priming studies investigated the recognition of English words spoken with a foreign accent. Auditory English primes were either typical of a Dutch accent or typical of a Japanese accent in English and were presented to both Dutch and Japanese L2 listeners. Lexical-decision times to subsequent visual target words revealed that foreign-accented words can facilitate word recognition for L2 listeners if at least one of two requirements is met: the foreign-accented production is in accordance with the language background of the L2 listener, or the foreign accent is perceptually confusable with the standard pronunciation for the L2 listener. If neither one of the requirements is met, no facilitatory effect of foreign accents on L2 word recognition is found. Taken together, these findings suggest that linguistic experience with a foreign accent affects the ability to recognize words carrying this accent, and there is furthermore a general benefit for L2 listeners for recognizing foreign-accented words that are perceptually confusable with the standard pronunciation.
  • Weber, K., & Lavric, A. (2008). Syntactic anomaly elicits a lexico-semantic (N400) ERP effect in the second but not in the first language. Psychophysiology, 45(6), 920-925. doi:10.1111/j.1469-8986.2008.00691.x.

    Abstract

    Recent brain potential research into first versus second language (L1 vs. L2) processing revealed striking responses to morphosyntactic features absent in the mother tongue. The aim of the present study was to establish whether the presence of comparable morphosyntactic features in L1 leads to more similar electrophysiological L1 and L2 profiles. ERPs were acquired while German-English bilinguals and native speakers of English read sentences. Some sentences were meaningful and well formed, whereas others contained morphosyntactic or semantic violations in the final word. In addition to the expected P600 component, morphosyntactic violations in L2 but not L1 led to an enhanced N400. This effect may suggest either that resolution of morphosyntactic anomalies in L2 relies on the lexico-semantic system or that the weaker/slower morphological mechanisms in L2 lead to greater sentence wrap-up difficulties known to result in N400 enhancement.
  • Weber, A., & Paris, G. (2004). The origin of the linguistic gender effect in spoken-word recognition: Evidence from non-native listening. In K. Forbus, D. Gentner, & T. Tegier (Eds.), Proceedings of the 26th Annual Meeting of the Cognitive Science Society. Mahwah, NJ: Erlbaum.

    Abstract

    Two eye-tracking experiments examined linguistic gender effects in non-native spoken-word recognition. French participants, who knew German well, followed spoken instructions in German to click on pictures on a computer screen (e.g., Wo befindet sich die Perle, “where is the pearl”) while their eye movements were monitored. The name of the target picture was preceded by a gender-marked article in the instructions. When a target and a competitor picture (with phonologically similar names) were of the same gender in both German and French, French participants fixated competitor pictures more than unrelated pictures. However, when target and competitor were of the same gender in German but of different gender in French, early fixations to the competitor picture were reduced. Competitor activation in the non-native language was seemingly constrained by native gender information. German listeners showed no such viewing time difference. The results speak against a form-based account of the linguistic gender effect. They rather support the notion that the effect originates from the grammatical level of language processing.
  • Weber, A. (2000). The role of phonotactics in the segmentation of native and non-native continuous speech. In A. Cutler, J. M. McQueen, & R. Zondervan (Eds.), Proceedings of SWAP, Workshop on Spoken Word Access Processes. Nijmegen: MPI for Psycholinguistics.

    Abstract

    Previous research has shown that listeners make use of their knowledge of phonotactic constraints to segment speech into individual words. The present study investigates the influence of phonotactics when segmenting a non-native language. German and English listeners detected embedded English words in nonsense sequences. German listeners also had knowledge of English, but English listeners had no knowledge of German. Word onsets were either aligned with a syllable boundary or not, according to the phonotactics of the two languages. Words aligned with either German or English phonotactic boundaries were easier for German listeners to detect than words without such alignment. Responses of English listeners were influenced primarily by English phonotactic alignment. The results suggest that both native and non-native phonotactic constraints influence lexical segmentation of a non-native, but familiar, language.
  • Weber, A. (2008). What eye movements can tell us about spoken-language processing: A psycholinguistic survey. In C. M. Riehl (Ed.), Was ist linguistische Evidenz: Kolloquium des Zentrums Sprachenvielfalt und Mehrsprachigkeit, November 2006 (pp. 57-68). Aachen: Shaker.
  • Weber, A. (2008). What the eyes can tell us about spoken-language comprehension [Abstract]. Journal of the Acoustical Society of America, 124, 2474-2474.

    Abstract

    Lexical recognition is typically slower in L2 than in L1. Part of the difficulty comes from a not precise enough processing of L2 phonemes. Consequently, L2 listeners fail to eliminate candidate words that L1 listeners can exclude from competing for recognition. For instance, the inability to distinguish /r/ from /l/ in rocket and locker makes for Japanese listeners both words possible candidates when hearing their onset (e.g., Cutler, Weber, and Otake, 2006). The L2 disadvantage can, however, be dispelled: For L2 listeners, but not L1 listeners, L2 speech from a non-native talker with the same language background is known to be as intelligible as L2 speech from a native talker (e.g., Bent and Bradlow, 2003). A reason for this may be that L2 listeners have ample experience with segmental deviations that are characteristic for their own accent. On this account, only phonemic deviations that are typical for the listeners’ own accent will cause spurious lexical activation in L2 listening (e.g., English magic pronounced as megic for Dutch listeners). In this talk, I will present evidence from cross-modal priming studies with a variety of L2 listener groups, showing how the processing of phonemic deviations is accent-specific but withstands fine phonetic differences.
  • Weber, A., & Mueller, K. (2004). Word order variation in German main clauses: A corpus analysis. In Proceedings of the 20th International Conference on Computational Linguistics.

    Abstract

    In this paper, we present empirical data from a corpus study on the linear order of subjects and objects in German main clauses. The aim was to establish the validity of three well-known ordering constraints: given complements tend to occur before new complements, definite before indefinite, and pronoun before full noun phrase complements. Frequencies of occurrences were derived for subject-first and object-first sentences from the German Negra corpus. While all three constraints held on subject-first sentences, results for object-first sentences varied. Our findings suggest an influence of grammatical functions on the ordering of verb complements.
  • Wegener, C. (2008). A grammar of Savosavo: A Papuan language of the Solomon Islands. PhD Thesis, Radboud University Nijmegen, Njimegen.
  • Wegener, C. (2011). Expression of reciprocity in Savosavo. In N. Evans, A. Gaby, S. C. Levinson, & A. Majid (Eds.), Reciprocals and semantic typology (pp. 213-224). Amsterdam: Benjamins.

    Abstract

    This paper describes how reciprocity is expressed in the Papuan (i.e. non-Austronesian­) language Savosavo, spoken in the Solomon Islands. The main strategy is to use the reciprocal nominal mapamapa, which can occur in different NP positions and always triggers default third person singular masculine agreement, regardless of the number and gender of the referents. After a description of this as well as another strategy that is occasionally used (the ‘joint activity construction’), the paper will provide a detailed analysis of data elicited with set of video stimuli and show that the main strategy is used to describe even clearly asymmetric situations, as long as more than one person acts on more than one person in a joint activity.
  • Weissenborn, J. (1986). Learning how to become an interlocutor. The verbal negotiation of common frames of reference and actions in dyads of 7–14 year old children. In J. Cook-Gumperz, W. A. Corsaro, & J. Streeck (Eds.), Children's worlds and children's language (pp. 377-404). Berlin: Mouton de Gruyter.
  • Weissenborn, J. (1988). Von der demonstratio ad oculos zur Deixis am Phantasma. Die Entwicklung der lokalen Referenz bei Kindern. In Karl Bühler's Theory of Language. Proceedings of the Conference held at Kirchberg, August 26, 1984 and Essen, November 21–24, 1984 (pp. 257-276). Amsterdam: Benjamins.
  • Whelpton, M., Guðmundsdóttir Beck, þ., & Jordan, F. (2015). The semantics and morphology of household container names in Icelandic and Dutch. Language Sciences, 49, 67-81. doi:10.1016/j.langsci.2014.07.014.

    Abstract

    In this paper, we report an experiment on the naming of household containers in Dutch and Icelandic carried out as part of the Evolution of Semantic Systems project (EoSS; Majid et al., 2011). This naming experiment allows us to support and elaborate on a hypothesis by Malt et al. (2003) that productive morphology in the naming domain can have an influence on boundary placement within the extensional space. Specifically, we demonstrate that the Dutch diminutive -(t)je favours a cut between small items versus others, whereas Icelandic, which does not use the diminutive in this domain, favours a cut between large items and others. This is not a typological effect, as Dutch and Icelandic are both Germanic languages and both have diminutive morphology available in principle. We find no evidence that the diminutive produces a proliferation of terms and/or fine-grained nesting within the extensional domain. Rather, the Dutch diminutive favours a more even distribution of terms across the space whereas Icelandic favours broad inclusive terms with a number of narrower specialist terms. Further, the extensional space defined by the diminutive is not associated with its own clear prototypical exemplar. Using evidence from compounding and modification, we also consider which semantic features are prominent in differentiating categories within the domain. By far the most prominent in both languages is the inferred contents of the container. Other than contents, however, the languages differ in the range and prominence of features such as intended usage or material of composition. Our results demonstrate that in order to understand the processes that produce semantic divisions of basic object classes, we should consider fine-grained analyses of closely related languages alongside analyses of typologically different languages.
  • Whitehead, H., & Hersh, T. A. (2022). Posterior probabilities of membership of repertoires in acoustic clades. PLoS One, 17(4): e0267501. doi:10.1371/journal.pone.0267501.

    Abstract

    Recordings of calls may be used to assess population structure for acoustic species. This can be particularly effective if there are identity calls, produced nearly exclusively by just one population segment. The identity call method, IDcall, classifies calls into types using contaminated mixture models, and then clusters repertoires of calls into identity clades (potential population segments) using identity calls that are characteristic of the repertoires in each identity clade. We show how to calculate the Bayesian posterior probabilities that each repertoire is a member of each identity clade, and display this information as a stacked bar graph. This methodology (IDcallPP) is introduced using the output of IDcall but could easily be adapted to estimate posterior probabilities of clade membership when acoustic clades are delineated using other methods. This output is similar to that of the STRUCTURE software which uses molecular genetic data to assess population structure and has become a standard in conservation genetics. The technique introduced here should be a valuable asset to those who use acoustic data to address evolution, ecology, or conservation, and creates a methodological and conceptual bridge between geneticists and acousticians who aim to assess population structure.
  • Whitehouse, A. J., Bishop, D. V., Ang, Q., Pennell, C. E., & Fisher, S. E. (2011). CNTNAP2 variants affect early language development in the general population. Genes, Brain and Behavior, 10, 451-456. doi:10.1111/j.1601-183X.2011.00684.x.

    Abstract

    Early language development is known to be under genetic influence, but the genes affecting normal variation in the general population remain largely elusive. Recent studies of disorder reported that variants of the CNTNAP2 gene are associated both with language deficits in specific language impairment (SLI) and with language delays in autism. We tested the hypothesis that these CNTNAP2 variants affect communicative behavior, measured at 2 years of age in a large epidemiological sample, the Western Australian Pregnancy Cohort (Raine) Study. Singlepoint analyses of 1149 children (606 males, 543 emales) revealed patterns of association which were strikingly reminiscent of those observed in previous investigations of impaired language, centered on the same genetic markers, and with a consistent direction of effect (rs2710102, p = .0239; rs759178, p = .0248). Based on these findings we performed analyses of four-marker haplotypes of rs2710102- s759178-rs17236239-rs2538976, and identified significant association (haplotype TTAA, p = .049; haplotype GCAG, p = .0014). Our study suggests that common variants in the exon 13-15 region of CNTNAP2 influence early language acquisition, as assessed at age 2, in the general population. We propose that these CNTNAP2 variants increase susceptibility to SLI or autism when they occur together with other risk factors.

    Additional information

    Whitehouse_Additional_Information.doc
  • Widlok, T. (2004). Ethnography in language Documentation. Language Archive Newsletter, 1(3), 4-6.
  • Widlok, T., Rapold, C. J., & Hoymann, G. (2008). Multimedia analysis in documentation projects: Kinship, interrogatives and reciprocals in ǂAkhoe Haiǁom. In K. D. Harrison, D. S. Rood, & A. Dwyer (Eds.), Lessons from documented endangered languages (pp. 355-370). Amsterdam: Benjamins.

    Abstract

    This contribution emphasizes the role of multimedia data not only for archiving languages but also for creating opportunities for innovative analyses. In the case at hand, video material was collected as part of the documentation of Akhoe Haiom, a Khoisan language spoken in northern Namibia. The multimedia documentation project brought together linguistic and anthropological work to highlight connections between specialized domains, namely kinship terminology, interrogatives and reciprocals. These connections would have gone unnoticed or undocumented in more conventional modes of language description. It is suggested that such an approach may be particularly appropriate for the documentation of endangered languages since it directs the focus of attention away from isolated traits of languages towards more complex practices of communication that are also frequently threatened with extinction.
  • Widlok, T. (2008). Landscape unbounded: Space, place, and orientation in ≠Akhoe Hai// om and beyond. Language Sciences, 30(2/3), 362-380. doi:10.1016/j.langsci.2006.12.002.

    Abstract

    Even before it became a common place to assume that “the Eskimo have a hundred words for snow” the languages of hunting and gathering people have played an important role in debates about linguistic relativity concerning geographical ontologies. Evidence from languages of hunter-gatherers has been used in radical relativist challenges to the overall notion of a comparative typology of generic natural forms and landscapes as terms of reference. It has been invoked to emphasize a personalized relationship between humans and the non-human world. It is against this background that this contribution discusses the landscape terminology of ≠Akhoe Hai//om, a Khoisan language spoken by “Bushmen” in Namibia. Landscape vocabulary is ubiquitous in ≠Akhoe Hai//om due to the fact that the landscape plays a critical role in directionals and other forms of “topographical gossip” and due to merges between landscape and group terminology. This system of landscape-cum-group terminology is outlined and related to the use of place names in the area.
  • Widlok, T. (2008). The dilemmas of walking: A comparative view. In T. Ingold, & J. L. Vergunst (Eds.), Ways of walking: Ethnography and practice on foot (pp. 51-66). Aldershot: Ashgate.
  • Wierenga, L. M., Doucet, G. E., Dima, D., Agartz, I., Aghajani, M., Akudjedu, T. N., Albajes-Eizagirre, A., Alnæs, D., Alpert, K. I., Andreassen, O. A., Anticevic, A., Asherson, P., Banaschewski, T., Bargallo, N., Baumeister, S., Baur-Streubel, R., Bertolino, A., Bonvino, A., Boomsma, D. I., Borgwardt, S. and 139 moreWierenga, L. M., Doucet, G. E., Dima, D., Agartz, I., Aghajani, M., Akudjedu, T. N., Albajes-Eizagirre, A., Alnæs, D., Alpert, K. I., Andreassen, O. A., Anticevic, A., Asherson, P., Banaschewski, T., Bargallo, N., Baumeister, S., Baur-Streubel, R., Bertolino, A., Bonvino, A., Boomsma, D. I., Borgwardt, S., Bourque, J., Den Braber, A., Brandeis, D., Breier, A., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Busatto, G. F., Calhoun, V. D., Canales-Rodríguez, E. J., Cannon, D. M., Caseras, X., Castellanos, F. X., Chaim-Avancini, T. M., Ching, C. R. K., Clark, V. P., Conrod, P. J., Conzelmann, A., Crivello, F., Davey, C. G., Dickie, E. W., Ehrlich, S., Van 't Ent, D., Fisher, S. E., Fouche, J.-P., Franke, B., Fuentes-Claramonte, P., De Geus, E. J. C., Di Giorgio, A., Glahn, D. C., Gotlib, I. H., Grabe, H. J., Gruber, O., Gruner, P., Gur, R. E., Gur, R. C., Gurholt, T. P., De Haan, L., Haatveit, B., Harrison, B. J., Hartman, C. A., Hatton, S. N., Heslenfeld, D. J., Van den Heuvel, O. A., Hickie, I. B., Hoekstra, P. J., Hohmann, S., Holmes, A. J., Hoogman, M., Hosten, N., Howells, F. M., Hulshoff Pol, H. E., Huyser, C., Jahanshad, N., James, A. C., Jiang, J., Jönsson, E. G., Joska, J. A., Kalnin, A. J., Karolinska Schizophrenia Project (KaSP) Consortium, Klein, M., Koenders, L., Kolskår, K. K., Krämer, B., Kuntsi, J., Lagopoulos, J., Lazaro, L., Lebedeva, I. S., Lee, P. H., Lochner, C., Machielsen, M. W. J., Maingault, S., Martin, N. G., Martínez-Zalacaín, I., Mataix-Cols, D., Mazoyer, B., McDonald, B. C., McDonald, C., McIntosh, A. M., McMahon, K. L., McPhilemy, G., Van der Meer, D., Menchón, J. M., Naaijen, J., Nyberg, L., Oosterlaan, J., Paloyelis, Y., Pauli, P., Pergola, G., Pomarol-Clotet, E., Portella, M. J., Radua, J., Reif, A., Richard, G., Roffman, J. L., Rosa, P. G. P., Sacchet, M. D., Sachdev, P. S., Salvador, R., Sarró, S., Satterthwaite, T. D., Saykin, A. J., Serpa, M. H., Sim, K., Simmons, A., Smoller, J. W., Sommer, I. E., Soriano-Mas, C., Stein, D. J., Strike, L. T., Szeszko, P. R., Temmingh, H. S., Thomopoulos, S. I., Tomyshev, A. S., Trollor, J. N., Uhlmann, A., Veer, I. M., Veltman, D. J., Voineskos, A., Völzke, H., Walter, H., Wang, L., Wang, Y., Weber, B., Wen, W., West, J. D., Westlye, L. T., Whalley, H. C., Williams, S. C. R., Wittfeld, K., Wolf, D. H., Wright, M. J., Yoncheva, Y. N., Zanetti, M. V., Ziegler, G. C., De Zubicaray, G. I., Thompson, P. M., Crone, E. A., Frangou, S., & Tamnes, C. K. (2022). Greater male than female variability in regional brain structure across the lifespan. Human Brain Mapping, 43(1), 470-499. doi:10.1002/hbm.25204.

    Abstract

    For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta‐Analysis) Consortium presents the largest‐ever mega‐analysis of sex differences in variability of brain structure, based on international data spanning nine decades of life. Subcortical volumes, cortical surface area and cortical thickness were assessed in MRI data of 16,683 healthy individuals 1‐90 years old (47% females). We observed significant patterns of greater male than female between‐subject variance for all subcortical volumetric measures, all cortical surface area measures, and 60% of cortical thickness measures. This pattern was stable across the lifespan for 50% of the subcortical structures, 70% of the regional area measures, and nearly all regions for thickness. Our findings that these sex differences are present in childhood implicate early life genetic or gene‐environment interaction mechanisms. The findings highlight the importance of individual differences within the sexes, that may underpin sex‐specific vulnerability to disorders.
  • Wilkin, K., & Holler, J. (2011). Speakers’ use of ‘action’ and ‘entity’ gestures with definite and indefinite references. In G. Stam, & M. Ishino (Eds.), Integrating gestures: The interdisciplinary nature of gesture (pp. 293-308). Amsterdam: John Benjamins.

    Abstract

    Common ground is an essential prerequisite for coordination in social interaction, including language use. When referring back to a referent in discourse, this referent is ‘given information’ and therefore in the interactants’ common ground. When a referent is being referred to for the first time, a speaker introduces ‘new information’. The analyses reported here are on gestures that accompany such references when they include definite and indefinite grammatical determiners. The main finding from these analyses is that referents referred to by definite and indefinite articles were equally often accompanied by gesture, but speakers tended to accompany definite references with gestures focusing on action information and indefinite references with gestures focusing on entity information. The findings suggest that speakers use speech and gesture together to design utterances appropriate for speakers with whom they share common ground.

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  • Willems, R. M., Ozyurek, A., & Hagoort, P. (2008). Seeing and hearing meaning: ERP and fMRI evidence of word versus picture integration into a sentence context. Journal of Cognitive Neuroscience, 20, 1235-1249. doi:10.1162/jocn.2008.20085.

    Abstract

    Understanding language always occurs within a situational context and, therefore, often implies combining streams of information from different domains and modalities. One such combination is that of spoken language and visual information, which are perceived together in a variety of ways during everyday communication. Here we investigate whether and how words and pictures differ in terms of their neural correlates when they are integrated into a previously built-up sentence context. This is assessed in two experiments looking at the time course (measuring event-related potentials, ERPs) and the locus (using functional magnetic resonance imaging, fMRI) of this integration process. We manipulated the ease of semantic integration of word and/or picture to a previous sentence context to increase the semantic load of processing. In the ERP study, an increased semantic load led to an N400 effect which was similar for pictures and words in terms of latency and amplitude. In the fMRI study, we found overlapping activations to both picture and word integration in the left inferior frontal cortex. Specific activations for the integration of a word were observed in the left superior temporal cortex. We conclude that despite obvious differences in representational format, semantic information coming from pictures and words is integrated into a sentence context in similar ways in the brain. This study adds to the growing insight that the language system incorporates (semantic) information coming from linguistic and extralinguistic domains with the same neural time course and by recruitment of overlapping brain areas.
  • Willems, R. M., Labruna, L., D'Esposito, M., Ivry, R., & Casasanto, D. (2011). A functional role for the motor system in language understanding: Evidence from Theta-Burst Transcranial Magnetic Stimulation. Psychological Science, 22, 849 -854. doi:10.1177/0956797611412387.

    Abstract

    Does language comprehension depend, in part, on neural systems for action? In previous studies, motor areas of the brain were activated when people read or listened to action verbs, but it remains unclear whether such activation is functionally relevant for comprehension. In the experiments reported here, we used off-line theta-burst transcranial magnetic stimulation to investigate whether a causal relationship exists between activity in premotor cortex and action-language understanding. Right-handed participants completed a lexical decision task, in which they read verbs describing manual actions typically performed with the dominant hand (e.g., “to throw,” “to write”) and verbs describing nonmanual actions (e.g., “to earn,” “to wander”). Responses to manual-action verbs (but not to nonmanual-action verbs) were faster after stimulation of the hand area in left premotor cortex than after stimulation of the hand area in right premotor cortex. These results suggest that premotor cortex has a functional role in action-language understanding.

    Additional information

    Supplementary materials Willems.pdf
  • Willems, R. M., Clevis, K., & Hagoort, P. (2011). Add a picture for suspense: Neural correlates of the interaction between language and visual information in the perception of fear. Social, Cognitive and Affective Neuroscience, 6, 404-416. doi:10.1093/scan/nsq050.

    Abstract

    We investigated how visual and linguistic information interact in the perception of emotion. We borrowed a phenomenon from film theory which states that presentation of an as such neutral visual scene intensifies the percept of fear or suspense induced by a different channel of information, such as language. Our main aim was to investigate how neutral visual scenes can enhance responses to fearful language content in parts of the brain involved in the perception of emotion. Healthy participants’ brain activity was measured (using functional magnetic resonance imaging) while they read fearful and less fearful sentences presented with or without a neutral visual scene. The main idea is that the visual scenes intensify the fearful content of the language by subtly implying and concretizing what is described in the sentence. Activation levels in the right anterior temporal pole were selectively increased when a neutral visual scene was paired with a fearful sentence, compared to reading the sentence alone, as well as to reading of non-fearful sentences presented with the same neutral scene. We conclude that the right anterior temporal pole serves a binding function of emotional information across domains such as visual and linguistic information.
  • Willems, R. M. (Ed.). (2015). Cognitive neuroscience of natural language use. Cambridge: Cambridge University Press.
  • Willems, R. M. (2015). Cognitive neuroscience of natural language use: Introduction. In Cognitive neuroscience of natural language use (pp. 1-7). Cambridge: Cambridge University Press.
  • Willems, R. M., Benn, Y., Hagoort, P., Tonia, I., & Varley, R. (2011). Communicating without a functioning language system: Implications for the role of language in mentalizing. Neuropsychologia, 49, 3130-3135. doi:10.1016/j.neuropsychologia.2011.07.023.

    Abstract

    A debated issue in the relationship between language and thought is how our linguistic abilities are involved in understanding the intentions of others (‘mentalizing’). The results of both theoretical and empirical work have been used to argue that linguistic, and more specifically, grammatical, abilities are crucial in representing the mental states of others. Here we contribute to this debate by investigating how damage to the language system influences the generation and understanding of intentional communicative behaviors. Four patients with pervasive language difficulties (severe global or agrammatic aphasia) engaged in an experimentally controlled non-verbal communication paradigm, which required signaling and understanding a communicative message. Despite their profound language problems they were able to engage in recipient design as well as intention recognition, showing similar indicators of mentalizing as have been observed in the neurologically healthy population. Our results show that aspects of the ability to communicate remain present even when core capacities of the language system are dysfunctional
  • Willems, R. M., Oostenveld, R., & Hagoort, P. (2008). Early decreases in alpha and gamma band power distinguish linguistic from visual information during spoken sentence comprehension. Brain Research, 1219, 78-90. doi:10.1016/j.brainres.2008.04.065.

    Abstract

    Language is often perceived together with visual information. This raises the question on how the brain integrates information conveyed in visual and/or linguistic format during spoken language comprehension. In this study we investigated the dynamics of semantic integration of visual and linguistic information by means of time-frequency analysis of the EEG signal. A modified version of the N400 paradigm with either a word or a picture of an object being semantically incongruous with respect to the preceding sentence context was employed. Event-Related Potential (ERP) analysis showed qualitatively similar N400 effects for integration of either word or picture. Time-frequency analysis revealed early specific decreases in alpha and gamma band power for linguistic and visual information respectively. We argue that these reflect a rapid context-based analysis of acoustic (word) or visual (picture) form information. We conclude that although full semantic integration of linguistic and visual information occurs through a common mechanism, early differences in oscillations in specific frequency bands reflect the format of the incoming information and, importantly, an early context-based detection of its congruity with respect to the preceding language context
  • Willems, R. M., & Casasanto, D. (2011). Flexibility in embodied language understanding. Frontiers in Psychology, 2, 116. doi:10.3389/fpsyg.2011.00116.

    Abstract

    Do people use sensori-motor cortices to understand language? Here we review neurocognitive studies of language comprehension in healthy adults and evaluate their possible contributions to theories of language in the brain. We start by sketching the minimal predictions that an embodied theory of language understanding makes for empirical research, and then survey studies that have been offered as evidence for embodied semantic representations. We explore four debated issues: first, does activation of sensori-motor cortices during action language understanding imply that action semantics relies on mirror neurons? Second, what is the evidence that activity in sensori-motor cortices plays a functional role in understanding language? Third, to what extent do responses in perceptual and motor areas depend on the linguistic and extra-linguistic context? And finally, can embodied theories accommodate language about abstract concepts? Based on the available evidence, we conclude that sensori-motor cortices are activated during a variety of language comprehension tasks, for both concrete and abstract language. Yet, this activity depends on the context in which perception and action words are encountered. Although modality-specific cortical activity is not a sine qua non of language processing even for language about perception and action, sensori-motor regions of the brain appear to make functional contributions to the construction of meaning, and should therefore be incorporated into models of the neurocognitive architecture of language.
  • Willems, R. M. (2011). Re-appreciating the why of cognition: 35 years after Marr and Poggio. Frontiers in Psychology, 2, 244. doi:10.3389/fpsyg.2011.00244.

    Abstract

    Marr and Poggio’s levels of description are one of the most well-known theoretical constructs of twentieth century cognitive science. It entails that behavior can and should be considered at three different levels: computation, algorithm, and implementation. In this contribution focus is on the computational level of description, the level that describes the “why” of cognition. I argue that the computational level should be taken as a starting point in devising experiments in cognitive (neuro)science. Instead, the starting point in empirical practice often is a focus on the stimulus or on some capacity of the cognitive system. The “why” of cognition tends to be ignored when designing research, and is not considered in subsequent inference from experimental results. The overall aim of this manuscript is to show how re-appreciation of the computational level of description as a starting point for experiments can lead to more informative experimentation.
  • Williams, N. M., Williams, H., Majounie, E., Norton, N., Glaser, B., Morris, H. R., Owen, M. J., & O'Donovan, M. C. (2008). Analysis of copy number variation using quantitative interspecies competitive PCR. Nucleic Acids Research, 36(17): e112. doi:10.1093/nar/gkn495.

    Abstract

    Over recent years small submicroscopic DNA copy-number variants (CNVs) have been highlighted as an important source of variation in the human genome, human phenotypic diversity and disease susceptibility. Consequently, there is a pressing need for the development of methods that allow the efficient, accurate and cheap measurement of genomic copy number polymorphisms in clinical cohorts. We have developed a simple competitive PCR based method to determine DNA copy number which uses the entire genome of a single chimpanzee as a competitor thus eliminating the requirement for competitive sequences to be synthesized for each assay. This results in the requirement for only a single reference sample for all assays and dramatically increases the potential for large numbers of loci to be analysed in multiplex. In this study we establish proof of concept by accurately detecting previously characterized mutations at the PARK2 locus and then demonstrating the potential of quantitative interspecies competitive PCR (qicPCR) to accurately genotype CNVs in association studies by analysing chromosome 22q11 deletions in a sample of previously characterized patients and normal controls.
  • Wilms, V., Drijvers, L., & Brouwer, S. (2022). The Effects of Iconic Gestures and Babble Language on Word Intelligibility in Sentence Context. Journal of Speech, Language, and Hearing Research, 65, 1822-1838. doi:10.1044/2022\_JSLHR-21-00387.

    Abstract

    Purpose:This study investigated to what extent iconic co-speech gestures helpword intelligibility in sentence context in two different linguistic maskers (nativevs. foreign). It was hypothesized that sentence recognition improves with thepresence of iconic co-speech gestures and with foreign compared to nativebabble.Method:Thirty-two native Dutch participants performed a Dutch word recogni-tion task in context in which they were presented with videos in which anactress uttered short Dutch sentences (e.g.,Ze begint te openen,“She starts toopen”). Participants were presented with a total of six audiovisual conditions: nobackground noise (i.e., clear condition) without gesture, no background noise withgesture, French babble without gesture, French babble with gesture, Dutch bab-ble without gesture, and Dutch babble with gesture; and they were asked to typedown what was said by the Dutch actress. The accurate identification of theaction verbs at the end of the target sentences was measured.Results:The results demonstrated that performance on the task was better inthe gesture compared to the nongesture conditions (i.e., gesture enhancementeffect). In addition, performance was better in French babble than in Dutchbabble.Conclusions:Listeners benefit from iconic co-speech gestures during commu-nication and from foreign background speech compared to native. Theseinsights into multimodal communication may be valuable to everyone whoengages in multimodal communication and especially to a public who oftenworks in public places where competing speech is present in the background.
  • De Wit, S. J., van der Werf, Y. D., Mataix-Cols, D., Trujillo, J. P., van Oppen, P., Veltman, D. J., & van den Heuvel, O. A. (2015). Emotion regulation before and after transcranial magnetic stimulation in obsessive compulsive disorder. Psychological Medicine, 45(14), 3059-3073. doi:10.1017/S0033291715001026.

    Abstract

    Impaired emotion regulation may underlie exaggerated emotional reactivity in patients with obsessive compulsive disorder (OCD), yet instructed emotion regulation has never been studied in the disorder. METHOD: This study aimed to assess the neural correlates of emotion processing and regulation in 43 medication-free OCD patients and 38 matched healthy controls, and additionally test if these can be modulated by stimulatory (patients) and inhibitory (controls) repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (dlPFC). Participants performed an emotion regulation task during functional magnetic resonance imaging before and after a single session of randomly assigned real or sham rTMS. Effect of group and rTMS were assessed on self-reported distress ratings and brain activity in frontal-limbic regions of interest. RESULTS: Patients had higher distress ratings than controls during emotion provocation, but similar rates of distress reduction after voluntary emotion regulation. OCD patients compared with controls showed altered amygdala responsiveness during symptom provocation and diminished left dlPFC activity and frontal-amygdala connectivity during emotion regulation. Real v. sham dlPFC stimulation differentially modulated frontal-amygdala connectivity during emotion regulation in OCD patients. CONCLUSIONS: We propose that the increased emotional reactivity in OCD may be due to a deficit in emotion regulation caused by a failure of cognitive control exerted by the dorsal frontal cortex. Modulatory rTMS over the left dlPFC may influence automatic emotion regulation capabilities by influencing frontal-limbic connectivity.
  • Wittek, A. (1998). Learning verb meaning via adverbial modification: Change-of-state verbs in German and the adverb "wieder" again. In A. Greenhill, M. Hughes, H. Littlefield, & H. Walsh (Eds.), Proceedings of the 22nd Annual Boston University Conference on Language Development (pp. 779-790). Somerville, MA: Cascadilla Press.
  • Witteman, M. J., Bardhan, N. P., Weber, A., & McQueen, J. M. (2015). Automaticity and stability of adaptation to foreign-accented speech. Language and Speech, 52(2), 168-189. doi:10.1177/0023830914528102.

    Abstract

    In three cross-modal priming experiments we asked whether adaptation to a foreign-accented speaker is automatic, and whether adaptation can be seen after a long delay between initial exposure and test. Dutch listeners were exposed to a Hebrew-accented Dutch speaker with two types of Dutch words: those that contained [ɪ] (globally accented words), and those in which the Dutch [i] was shortened to [ɪ] (specific accent marker words). Experiment 1, which served as a baseline, showed that native Dutch participants showed facilitatory priming for globally accented, but not specific accent, words. In experiment 2, participants performed a 3.5-minute phoneme monitoring task, and were tested on their comprehension of the accented speaker 24 hours later using the same cross-modal priming task as in experiment 1. During the phoneme monitoring task, listeners were asked to detect a consonant that was not strongly accented. In experiment 3, the delay between exposure and test was extended to 1 week. Listeners in experiments 2 and 3 showed facilitatory priming for both globally accented and specific accent marker words. Together, these results show that adaptation to a foreign-accented speaker can be rapid and automatic, and can be observed after a prolonged delay in testing.
  • Witteman, M. J., Bardhan, N. P., Weber, A., & McQueen, J. M. (2011). Adapting to foreign-accented speech: The role of delay in testing. Journal of the Acoustical Society of America. Program abstracts of the 162nd Meeting of the Acoustical Society of America, 130(4), 2443.

    Abstract

    Understanding speech usually seems easy, but it can become noticeably harder when the speaker has a foreign accent. This is because foreign accents add considerable variation to speech. Research on foreign-accented speech shows that participants are able to adapt quickly to this type of variation. Less is known, however, about longer-term maintenance of adaptation. The current study focused on long-term adaptation by exposing native listeners to foreign-accented speech on Day 1, and testing them on comprehension of the accent one day later. Comprehension was thus not tested immediately, but only after a 24 hour period. On Day 1, native Dutch listeners listened to the speech of a Hebrew learner of Dutch while performing a phoneme monitoring task that did not depend on the talker’s accent. In particular, shortening of the long vowel /i/ into /ɪ/ (e.g., lief [li:f], ‘sweet’, pronounced as [lɪf]) was examined. These mispronunciations did not create lexical ambiguities in Dutch. On Day 2, listeners participated in a cross-modal priming task to test their comprehension of the accent. The results will be contrasted with results from an experiment without delayed testing and related to accounts of how listeners maintain adaptation to foreign-accented speech.
  • Witteman, M. J., Weber, A., & McQueen, J. M. (2011). On the relationship between perceived accentedness, acoustic similarity, and processing difficulty in foreign-accented speech. In Proceedings of the 12th Annual Conference of the International Speech Communication Association (Interspeech 2011), Florence, Italy (pp. 2229-2232).

    Abstract

    Foreign-accented speech is often perceived as more difficult to understand than native speech. What causes this potential difficulty, however, remains unknown. In the present study, we compared acoustic similarity and accent ratings of American-accented Dutch with a cross-modal priming task designed to measure online speech processing. We focused on two Dutch diphthongs: ui and ij. Though both diphthongs deviated from standard Dutch to varying degrees and perceptually varied in accent strength, native Dutch listeners recognized words containing the diphthongs easily. Thus, not all foreign-accented speech hinders comprehension, and acoustic similarity and perceived accentedness are not always predictive of processing difficulties.
  • Wittenburg, P., Skiba, R., & Trilsbeek, P. (2004). Technology and Tools for Language Documentation. Language Archive Newsletter, 1(4), 3-4.
  • Wittenburg, P. (2004). The IMDI metadata concept. In S. F. Ferreira (Ed.), Workingmaterial on Building the LR&E Roadmap: Joint COCOSDA and ICCWLRE Meeting, (LREC2004). Paris: ELRA - European Language Resources Association.
  • Wittenburg, P. (2004). Training Course in Lithuania. Language Archive Newsletter, 1(2), 6-6.
  • Wittenburg, P., Brugman, H., Broeder, D., & Russel, A. (2004). XML-based language archiving. In Workshop Proceedings on XML-based Richly Annotaded Corpora (LREC2004) (pp. 63-69). Paris: ELRA - European Language Resources Association.
  • Wittenburg, P. (2008). Die CLARIN Forschungsinfrastruktur. ÖGAI-journal (Österreichische Gesellschaft für Artificial Intelligence), 27, 10-17.
  • Wittenburg, P., Gulrajani, G., Broeder, D., & Uneson, M. (2004). Cross-disciplinary integration of metadata descriptions. In M. Lino, M. Xavier, F. Ferreira, R. Costa, & R. Silva (Eds.), Proceedings of the 4th International Conference on Language Resources and Evaluation (LREC2004) (pp. 113-116). Paris: ELRA - European Language Resources Association.
  • Wittenburg, P., Dirksmeyer, R., Brugman, H., & Klaas, G. (2004). Digital formats for images, audio and video. Language Archive Newsletter, 1(1), 3-6.
  • Wittenburg, P., Johnson, H., Buchhorn, M., Brugman, H., & Broeder, D. (2004). Architecture for distributed language resource management and archiving. In M. Lino, M. Xavier, F. Ferreira, R. Costa, & R. Silva (Eds.), Proceedings of the 4th International Conference on Language Resources and Evaluation (LREC2004) (pp. 361-364). Paris: ELRA - European Language Resources Association.
  • Wittenburg, P. (2004). International Expert Meeting on Access Management for Distributed Language Archives. Language Archive Newsletter, 1(3), 12-12.
  • Wittenburg, P. (2004). Final review of INTERA. Language Archive Newsletter, 1(4), 11-12.
  • Wittenburg, P. (2004). LinguaPax Forum on Language Diversity, Sustainability, and Peace. Language Archive Newsletter, 1(3), 13-13.
  • Wittenburg, P. (2004). LREC conference 2004. Language Archive Newsletter, 1(3), 12-13.
  • Wittenburg, P. (2004). News from the Archive of the Max Planck Institute for Psycholinguistics. Language Archive Newsletter, 1(4), 12-12.
  • Wnuk, E., Verkerk, A., Levinson, S. C., & Majid, A. (2022). Color technology is not necessary for rich and efficient color language. Cognition, 229: 105223. doi:10.1016/j.cognition.2022.105223.

    Abstract

    The evolution of basic color terms in language is claimed to be stimulated by technological development, involving technological control of color or exposure to artificially colored objects. Accordingly, technologically “simple” non-industrialized societies are expected to have poor lexicalization of color, i.e., only rudimentary lexica of 2, 3 or 4 basic color terms, with unnamed gaps in the color space. While it may indeed be the case that technology stimulates lexical growth of color terms, it is sometimes considered a sine qua non for color salience and lexicalization. We provide novel evidence that this overlooks the role of the natural environment, and people's engagement with the environment, in the evolution of color vocabulary. We introduce the Maniq—nomadic hunter-gatherers with no color technology, but who have a basic color lexicon of 6 or 7 terms, thus of the same order as large languages like Vietnamese and Hausa, and who routinely talk about color. We examine color language in Maniq and compare it to available data in other languages to demonstrate it has remarkably high consensual color term usage, on a par with English, and high coding efficiency. This shows colors can matter even for non-industrialized societies, suggesting technology is not necessary for color language. Instead, factors such as perceptual prominence of color in natural environments, its practical usefulness across communicative contexts, and symbolic importance can all stimulate elaboration of color language.
  • Woensdregt, M., Jara-Ettinger, J., & Rubio-Fernandez, P. (2022). Language universals rely on social cognition: Computational models of the use of this and that to redirect the receiver’s attention. In J. Culbertson, A. Perfors, H. Rabagliati, & V. Ramenzoni (Eds.), Proceedings of the 44th Annual Conference of the Cognitive Science Society (CogSci 2022) (pp. 1382-1388). Toronto, Canada: Cognitive Science Society.

    Abstract

    Demonstratives—simple referential devices like this and that—are linguistic universals, but their meaning varies cross-linguistically. In languages like English and Italian, demonstratives are thought to encode the referent’s distance from the producer (e.g., that one means “the one far away from me”),
    while in others, like Portuguese and Spanish, they encode relative distance from both producer and receiver (e.g., aquel means “the one far away from both of us”). Here we propose that demonstratives are also sensitive to the receiver’s focus of attention, hence requiring a deeper form of social cognition
    than previously thought. We provide initial empirical and computational evidence for this idea, suggesting that producers use
    demonstratives to redirect the receiver’s attention towards the intended referent, rather than only to indicate its physical distance.
  • Li, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Ikram, M. K., Höhn, R., Vitart, V., Hewitt, A. W., Oexle, K., Mäkelä, K.-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C.-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K., Rahi, J. S. and 69 moreLi, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Ikram, M. K., Höhn, R., Vitart, V., Hewitt, A. W., Oexle, K., Mäkelä, K.-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C.-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K., Rahi, J. S., Cumberland, P. M., Martin, N. G., Sanfilippo, P. G., Lu, Y., Wang, Y. X., Hayward, C., Polašek, O., Campbell, H., Bencic, G., Wright, A. F., Wedenoja, J., Zeller, T., Schillert, A., Mirshahi, A., Lackner, K., Yip, S. P., Yap, M. K. H., Ried, J. S., Gieger, C., Murgia, F., Wilson, J. F., Fleck, B., Yazar, S., Vingerling, J. R., Hofman, A., Uitterlinden, A., Rivadeneira, F., Amin, N., Karssen, L., Oostra, B. A., Zhou, X., Teo, Y.-Y., Tai, E. S., Vithana, E., Barathi, V., Zheng, Y., Siantar, R. G., Neelam, K., Shin, Y., Lam, J., Yonova-Doing, E., Venturini, C., Hosseini, S. M., Wong, H.-S., Lehtimäki, T., Kähönen, M., Raitakari, O., Timpson, N. J., Evans, D. M., Khor, C.-C., Aung, T., Young, T. L., Mitchell, P., Klein, B., van Duijn, C. M., Meitinger, T., Jonas, J. B., Baird, P. N., Mackey, D. A., Wong, T. Y., Saw, S.-M., Pärssinen, O., Stambolian, D., Hammond, C. J., Klaver, C. C. W., Williams, C., Paterson, A. D., Bailey-Wilson, J. E., & Guggenheim, J. A. (2015). Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Human Genetics, 134, 131-146. doi:10.1007/s00439-014-1500-y.

    Abstract

    To identify genetic variants associated with refractive astigmatism in the general population, meta-analyses of genome-wide association studies were performed for: White Europeans aged at least 25 years (20 cohorts, N = 31,968); Asian subjects aged at least 25 years (7 cohorts, N = 9,295); White Europeans aged <25 years (4 cohorts, N = 5,640); and all independent individuals from the above three samples combined with a sample of Chinese subjects aged <25 years (N = 45,931). Participants were classified as cases with refractive astigmatism if the average cylinder power in their two eyes was at least 1.00 diopter and as controls otherwise. Genome-wide association analysis was carried out for each cohort separately using logistic regression. Meta-analysis was conducted using a fixed effects model. In the older European group the most strongly associated marker was downstream of the neurexin-1 (NRXN1) gene (rs1401327, P = 3.92E−8). No other region reached genome-wide significance, and association signals were lower for the younger European group and Asian group. In the meta-analysis of all cohorts, no marker reached genome-wide significance: The most strongly associated regions were, NRXN1 (rs1401327, P = 2.93E−07), TOX (rs7823467, P = 3.47E−07) and LINC00340 (rs12212674, P = 1.49E−06). For 34 markers identified in prior GWAS for spherical equivalent refractive error, the beta coefficients for genotype versus spherical equivalent, and genotype versus refractive astigmatism, were highly correlated (r = −0.59, P = 2.10E−04). This work revealed no consistent or strong genetic signals for refractive astigmatism; however, the TOX gene region previously identified in GWAS for spherical equivalent refractive error was the second most strongly associated region. Analysis of additional markers provided evidence supporting widespread genetic co-susceptibility for spherical and astigmatic refractive errors.
  • Wolf, M. C. (2022). Spoken and written word processing: Effects of presentation modality and individual differences in experience to written language. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Wolf, M. C. (2015). Het verschil tussen hardop en stillezen wat betreft leessnelheid en tekstbegrip en de invloed hierop van fonologisch bewustzijn, benoemsnelheid en visuele aandachtsspanne. Student Undergraduate Research E-journal, 1(1), 261-264. Retrieved from http://journals.library.tudelft.nl/index.php/sure/article/view/1025.

    Abstract

    In het onderwijs wordt aangenomen dat hardop en stillezen dezelfde processen zijn. In dit onderzoek wordt gekeken naar het verschil tussen hardop en stillezen wat betreft leessnelheid en tekstbegrip bij 90 kinderen uit groep 4. Ook wordt de invloed van de cognitieve vaardigheden fonologisch bewustzijn, benoemsnelheid en visuele aandachtsspanne op de verschillende leesmodi onderzocht. De participanten lazen stil sneller, maar begrepen de tekst beter hardop. De cognitieve vaardigheden correleerden met hardop en stillezen wat betreft leessnelheid, maar hingen in beide leesmodi niet samen met tekstbegrip. Hoewel hardop en stillezen samenhangen, onderstrepen deze bevindingen dat het verschillende leesmodi zijn.
  • Wolters, G., & Poletiek, F. H. (2008). Beslissen over aangiftes van seksueel misbruik bij kinderen. De Psycholoog, 43, 29-29.
  • Xiang, H., Van Leeuwen, T. M., Dediu, D., Roberts, L., Norris, D. G., & Hagoort, P. (2015). L2-proficiency-dependent laterality shift in structural connectivity of brain language pathways. Brain Connectivity, 5(6), 349-361. doi:10.1089/brain.2013.0199.

    Abstract

    Diffusion tensor imaging (DTI) and a longitudinal language learning approach were applied to investigate the relationship between the achieved second language (L2) proficiency during L2 learning and the reorganization of structural connectivity between core language areas. Language proficiency tests and DTI scans were obtained from German students before and after they completed an intensive 6-week course of the Dutch language. In the initial learning stage, with increasing L2 proficiency, the hemispheric dominance of the BA6-temporal pathway (mainly along the arcuate fasciculus) shifted from the left to the right hemisphere. With further increased proficiency, however, lateralization dominance was again found in the left BA6-temporal pathway. This result is consistent with reports in the literature that imply a stronger involvement of the right hemisphere in L2-processing especially for less proficient L2-speakers. This is the first time that a L2-proficiency-dependent laterality shift in structural connectivity of language pathways during L2 acquisition has been observed to shift from left to right, and back to left hemisphere dominance with increasing L2-proficiency. We additionally find that changes in fractional anisotropy values after the course are related to the time elapsed between the two scans. The results suggest that structural connectivity in (at least part of) the perisylvian language network may be subject to fast dynamic changes following language learning
  • Li, X., Yang, Y., & Hagoort, P. (2008). Pitch accent and lexical tone processing in Chinese discourse comprehension: An ERP study. Brain Research, 1222, 192-200. doi:10.1016/j.brainres.2008.05.031.

    Abstract

    In the present study, event-related brain potentials (ERP) were recorded to investigate the role of pitch accent and lexical tone in spoken discourse comprehension. Chinese was used as material to explore the potential difference in the nature and time course of brain responses to sentence meaning as indicated by pitch accent and to lexical meaning as indicated by tone. In both cases, the pitch contour of critical words was varied. The results showed that both inconsistent pitch accent and inconsistent lexical tone yielded N400 effects, and there was no interaction between them. The negativity evoked by inconsistent pitch accent had the some topography as that evoked by inconsistent lexical tone violation, with a maximum over central–parietal electrodes. Furthermore, the effect for the combined violations was the sum of effects for pure pitch accent and pure lexical tone violation. However, the effect for the lexical tone violation appeared approximately 90 ms earlier than the effect of the pitch accent violation. It is suggested that there might be a correspondence between the neural mechanism underlying pitch accent and lexical meaning processing in context. They both reflect the integration of the current information into a discourse context, independent of whether the current information was sentence meaning indicated by accentuation, or lexical meaning indicated by tone. In addition, lexical meaning was processed earlier than sentence meaning conveyed by pitch accent during spoken language processing.
  • Yang, J. (2022). Discovering the units in language cognition: From empirical evidence to a computational model. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Yang, J., Van den Bosch, A., & Frank, S. L. (2022). Unsupervised text segmentation predicts eye fixations during reading. Frontiers in Artificial Intelligence, 5: 731615. doi:10.3389/frai.2022.731615.

    Abstract

    Words typically form the basis of psycholinguistic and computational linguistic studies about sentence processing. However, recent evidence shows the basic units during reading, i.e., the items in the mental lexicon, are not always words, but could also be sub-word and supra-word units. To recognize these units, human readers require a cognitive mechanism to learn and detect them. In this paper, we assume eye fixations during reading reveal the locations of the cognitive units, and that the cognitive units are analogous with the text units discovered by unsupervised segmentation models. We predict eye fixations by model-segmented units on both English and Dutch text. The results show the model-segmented units predict eye fixations better than word units. This finding suggests that the predictive performance of model-segmented units indicates their plausibility as cognitive units. The Less-is-Better (LiB) model, which finds the units that minimize both long-term and working memory load, offers advantages both in terms of prediction score and efficiency among alternative models. Our results also suggest that modeling the least-effort principle for the management of long-term and working memory can lead to inferring cognitive units. Overall, the study supports the theory that the mental lexicon stores not only words but also smaller and larger units, suggests that fixation locations during reading depend on these units, and shows that unsupervised segmentation models can discover these units.
  • Zavala, R. (1997). Functional analysis of Akatek voice constructions. International Journal of American Linguistics, 63(4), 439-474.

    Abstract

    L'A. étudie les corrélations entre structure syntaxique et fonction pragmatique dans les alternances de voix en akatek, une langue maya appartenant au sous-groupe Q'anjob'ala. Les alternances pragmatiques de voix sont les mécanismes par lesquels les langues encodent les différents degrés de topicalité des deux principaux participants d'un événement sémantiquement transitif, l'agent et le patient. A l'aide d'une analyse quantitative, l'A. évalue la topicalité de ces participants et identifie les structures syntaxiques permettant d'exprimer les quatre principales fonctions de voix en akatek : active-directe, inverse, passive et antipassive
  • Zavala, R. (2000). Multiple classifier systems in Akatek (Mayan). In G. Senft (Ed.), Systems of nominal classification (pp. 114-146). Cambridge University Press.
  • Zeller, J., Bylund, E., & Lewis, A. G. (2022). The parser consults the lexicon in spite of transparent gender marking: EEG evidence from noun class agreement processing in Zulu. Cognition, 226: 105148. doi:10.1016/j.cognition.2022.105148.

    Abstract

    In sentence comprehension, the parser in many languages has the option to use both the morphological form of a noun and its lexical representation when evaluating agreement. The additional step of consulting the lexicon incurs processing costs, and an important question is whether the parser takes that step even when the formal cues alone are sufficiently reliable to evaluate agreement. Our study addressed this question using electrophysiology in Zulu, a language where both grammatical gender and number features are reliably expressed formally by noun class prefixes, but only gender features are lexically specified. We observed reduced, more topographically focal LAN, and more frontally distributed alpha/beta power effects for gender compared to number agreement violations. These differences provide evidence that for gender mismatches, even though the formal cues are reliable, the parser nevertheless takes the additional step of consulting the noun's lexical representation, a step which is not available for number.

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  • Zeshan, U. (2004). Basic English course taught in Indian Sign Language (Ali Yavar Young National Institute for Hearing Handicapped, Ed.). National Institute for the Hearing Handicapped: Mumbai.
  • Zeshan, U. (2004). Interrogative constructions in sign languages - Cross-linguistic perspectives. Language, 80(1), 7-39.

    Abstract

    This article reports on results from a broad crosslinguistic study based on data from thirty-five signed languages around the world. The study is the first of its kind, and the typological generalizations presented here cover the domain of interrogative structures as they appear across a wide range of geographically and genetically distinct signed languages. Manual and nonmanual ways of marking basic types of questions in signed languages are investigated. As a result, it becomes clear that the range of crosslinguistic variation is extensive for some subparameters, such as the structure of question-word paradigms, while other parameters, such as the use of nonmanual expressions in questions, show more similarities across signed languages. Finally, it is instructive to compare the findings from signed language typology to relevant data from spoken languages at a more abstract, crossmodality level.
  • Zeshan, U. (2004). Hand, head and face - negative constructions in sign languages. Linguistic Typology, 8(1), 1-58. doi:10.1515/lity.2004.003.

    Abstract

    This article presents a typology of negative constructions across a substantial number of sign languages from around the globe. After situating the topic within the wider context of linguistic typology, the main negation strategies found across sign languages are described. Nonmanual negation includes the use of head movements and facial expressions for negation and is of great importance in sign languages as well as particularly interesting from a typological point of view. As far as manual signs are concerned, independent negative particles represent the dominant strategy, but there are also instances of irregular negation in most sign languages. Irregular negatives may take the form of suppletion, cliticisation, affixing, or internal modification of a sign. The results of the study lead to interesting generalisations about similarities and differences between negatives in signed and spoken languages.
  • Zeshan, U., & Panda, S. (2011). Reciprocals constructions in Indo-Pakistani sign language. In N. Evans, & A. Gaby (Eds.), Reciprocals and semantic typology (pp. 91-113). Amsterdam: Benjamins.

    Abstract

    Indo-Pakistani Sign Language (IPSL) is the sign language used by deaf communities in a large region across India and Pakistan. This visual-gestural language has a dedicated construction for specifically expressing reciprocal relationships, which can be applied to agreement verbs and to auxiliaries. The reciprocal construction relies on a change in the movement pattern of the signs it applies to. In addition, IPSL has a number of other strategies which can have a reciprocal interpretation, and the IPSL lexicon includes a good number of inherently reciprocal signs. All reciprocal expressions can be modified in complex ways that rely on the grammatical use of the sign space. Considering grammaticalisation and lexicalisation processes linking some of these constructions is also important for a better understanding of reciprocity in IPSL.
  • Zeshan, U., & Perniss, P. M. (2008). Possessive and existential constructions in sign languages. Nijmegen: Ishara Press.
  • Zhang, Q., Zhou, Y., & Lou, H. (2022). The dissociation between age of acquisition and word frequency effects in Chinese spoken picture naming. Psychological Research, 86, 1918-1929. doi:10.1007/s00426-021-01616-0.

    Abstract

    This study aimed to examine the locus of age of acquisition (AoA) and word frequency (WF) effects in Chinese spoken picture naming, using a picture–word interference task. We conducted four experiments manipulating the properties of picture names (AoA in Experiments 1 and 2, while controlling WF; and WF in Experiments 3 and 4, while controlling AoA), and the relations between distractors and targets (semantic or phonological relatedness). Both Experiments 1 and 2 demonstrated AoA effects in picture naming; pictures of early acquired concepts were named faster than those acquired later. There was an interaction between AoA and semantic relatedness, but not between AoA and phonological relatedness, suggesting localisation of AoA effects at the stage of lexical access in picture naming. Experiments 3 and 4 demonstrated WF effects: pictures of high-frequency concepts were named faster than those of low-frequency concepts. WF interacted with both phonological and semantic relatedness, suggesting localisation of WF effects at multiple levels of picture naming, including lexical access and phonological encoding. Our findings show that AoA and WF effects exist in Chinese spoken word production and may arise at related processes of lexical selection.
  • Zhang, Y., & Yu, C. (2022). Examining real-time attention dynamics in parent-infant picture book reading. In J. Culbertson, A. Perfors, H. Rabagliati, & V. Ramenzoni (Eds.), Proceedings of the 44th Annual Conference of the Cognitive Science Society (CogSci 2022) (pp. 1367-1374). Toronto, Canada: Cognitive Science Society.

    Abstract

    Picture book reading is a common word-learning context from which parents repeatedly name objects to their child and it has been found to facilitate early word learning. To learn the correct word-object mappings in a book-reading context, infants need to be able to link what they see with what they hear. However, given multiple objects on every book page, it is not clear how infants direct their attention to objects named by parents. The aim of the current study is to examine how infants mechanistically discover the correct word-object mappings during book reading in real time. We used head-mounted eye-tracking during parent-infant picture book reading and measured the infant's moment-by-moment visual attention to the named referent. We also examined how gesture cues provided by both the child and the parent may influence infants' attention to the named target. We found that although parents provided many object labels during book reading, infants were not able to attend to the named objects easily. However, their abilities to follow and use gestures to direct the other social partner’s attention increase the chance of looking at the named target during parent naming.
  • Zhang, Y., Yurovsky, D., & Yu, C. (2015). Statistical word learning is a continuous process: Evidence from the human simulation paradigm. In D. Noelle, R. Dale, A. Warlaumont, J. Yoshimi, T. Matlock, C. D. Jennings, & P. P. Maglio (Eds.), Proceedings of the 37th Annual Meeting of the Cognitive Science Society (CogSci 2015) (pp. 2422-2427). Austin: Cognitive Science Society.

    Abstract

    In the word-learning domain, both adults and young children are able to find the correct referent of a word from highly ambiguous contexts that involve many words and objects by computing distributional statistics across the co-occurrences of words and referents at multiple naming moments (Yu & Smith, 2007; Smith & Yu, 2008). However, there is still debate regarding how learners accumulate distributional information to learn object labels in natural learning environments, and what underlying learning mechanism learners are most likely to adopt. Using the Human Simulation Paradigm (Gillette, Gleitman, Gleitman & Lederer, 1999), we found that participants’ learning performance gradually improved and that their ability to remember and carry over partial knowledge from past learning instances facilitated subsequent learning. These results support the statistical learning model that word learning is a continuous process.
  • Wu, S., Zhang, D., Li, X., Zhao, J., Sun, X., Shi, L., Mao, Y., Zhang, Y., & Jiang, F. (2022). Siblings and Early Childhood Development: Evidence from a Population-Based Cohort in Preschoolers from Shanghai. International Journal of Environmental Research and Public Health, 19(9): 5739. doi:10.3390/ijerph19095739.

    Abstract

    Background: The current study aims to investigate the association between the presence of a sibling and early childhood development (ECD). (2) Methods: Data were obtained from a large-scale population-based cohort in Shanghai. Children were followed from three to six years old. Based on birth order, the sample was divided into four groups: single child, younger child, elder child, and single-elder transfer (transfer from single-child to elder-child). Psychosocial well-being and school readiness were assessed with the total difficulties score from the Strengths and Difficulties Questionnaire (SDQ) and the overall development score from the early Human Capability Index (eHCI), respectively. A multilevel model was conducted to evaluate the main effect of each sibling group and the group × age interaction effect on psychosocial well-being and school readiness. (3) Results: Across all measures, children in the younger child group presented with lower psychosocial problems (β = −0.96, 95% CI: −1.44, −0.48, p < 0.001) and higher school readiness scores (β = 1.56, 95% CI: 0.61, 2.51, p = 0.001). No significant difference, or marginally significant difference, was found between the elder group and the single-child group. Compared to the single-child group, the single-elder transfer group presented with slower development on both psychosocial well-being (Age × Group: β = 0.37, 95% CI: 0.18, 0.56, p < 0.001) and school readiness (Age × Group: β = −0.75, 95% CI: −1.10, −0.40, p < 0.001). The sibling-ECD effects did not differ between children from families of low versus high socioeconomic status. (4) Conclusion: The current study suggested the presence of a sibling was not associated with worse development outcomes in general. Rather, children with an elder sibling are more likely to present with better ECD.
  • Zhao, H., Zhou, W., Yao, Z., Wan, Y., Cao, J., Zhang, L., Zhao, J., Li, H., Zhou, R., Li, B., Wei, G., Zhang, Z., French, C. A., Dekker, J. D., Yang, Y., Fisher, S. E., Tucker, H. O., & Guo, X. (2015). Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Developmental Biology, 398, 242-254. doi:10.1016/j.ydbio.2014.12.007.

    Abstract

    Osteoblast induction and differentiation in developing long bones is dynamically controlled by the opposing action of transcriptional activators and repressors. In contrast to the long list of activators that have been discovered over past decades, the network of repressors is not well-defined. Here we identify the expression of Foxp1/2/4 proteins, comprised of Forkhead-box (Fox) transcription factors of the Foxp subfamily, in both perichondrial skeletal progenitors and proliferating chondrocytes during endochondral ossification. Mice carrying loss-of-function and gain-of-function Foxp mutations had gross defects in appendicular skeleton formation. At the cellular level, over-expression of Foxp1/2/4 in chondroctyes abrogated osteoblast formation and chondrocyte hypertrophy. Conversely, single or compound deficiency of Foxp1/2/4 in skeletal progenitors or chondrocytes resulted in premature osteoblast differentiation in the perichondrium, coupled with impaired proliferation, survival, and hypertrophy of chondrocytes in the growth plate. Foxp1/2/4 and Runx2 proteins interacted in vitro and in vivo, and Foxp1/2/4 repressed Runx2 transactivation function in heterologous cells. This study establishes Foxp1/2/4 proteins as coordinators of osteogenesis and chondrocyte hypertrophy in developing long bones and suggests that a novel transcriptional repressor network involving Foxp1/2/4 may regulate Runx2 during endochondral ossification.
  • Zhao, J., Yu, Z., Sun, X., Wu, S., Zhang, J., Zhang, D., Zhang, Y., & Jiang, F. (2022). Association between screen time trajectory and early childhood development in children in China. JAMA Pediatrics, 176(8), 768-775. doi:10.1001/jamapediatrics.2022.1630.

    Abstract

    Importance: Screen time has become an integral part of children's daily lives. Nevertheless, the developmental consequences of screen exposure in young children remain unclear.

    Objective: To investigate the screen time trajectory from 6 to 72 months of age and its association with children's development at age 72 months in a prospective birth cohort.

    Design, setting, and participants: Women in Shanghai, China, who were at 34 to 36 gestational weeks and had an expected delivery date between May 2012 and July 2013 were recruited for this cohort study. Their children were followed up at 6, 9, 12, 18, 24, 36, 48, and 72 months of age. Children's screen time was classified into 3 groups at age 6 months: continued low (ie, stable amount of screen time), late increasing (ie, sharp increase in screen time at age 36 months), and early increasing (ie, large amount of screen time in early stages that remained stable after age 36 months). Cognitive development was assessed by specially trained research staff in a research clinic. Of 262 eligible mother-offspring pairs, 152 dyads had complete data regarding all variables of interest and were included in the analyses. Data were analyzed from September 2019 to November 2021.

    Exposures: Mothers reported screen times of children at 6, 9, 12, 18, 24, 36, 48, and 72 months of age.

    Main outcomes and measures: The cognitive development of children was evaluated using the Wechsler Intelligence Scale for Children, 4th edition, at age 72 months. Social-emotional development was measured by the Strengths and Difficulties Questionnaire, which was completed by the child's mother. The study described demographic characteristics, maternal mental health, child's temperament at age 6 months, and mental development at age 12 months by subgroups clustered by a group-based trajectory model. Group difference was examined by analysis of variance.

    Results: A total of 152 mother-offspring dyads were included in this study, including 77 girls (50.7%) and 75 boys (49.3%) (mean [SD] age of the mothers was 29.7 [3.3] years). Children's screen time trajectory from age 6 to 72 months was classified into 3 groups: continued low (110 [72.4%]), late increasing (17 [11.2%]), and early increasing (25 [16.4%]). Compared with the continued low group, the late increasing group had lower scores on the Full-Scale Intelligence Quotient (β coefficient, -8.23; 95% CI, -15.16 to -1.30; P < .05) and the General Ability Index (β coefficient, -6.42; 95% CI, -13.70 to 0.86; P = .08); the early increasing group presented with lower scores on the Full-Scale Intelligence Quotient (β coefficient, -6.68; 95% CI, -12.35 to -1.02; P < .05) and the Cognitive Proficiency Index (β coefficient, -10.56; 95% CI, -17.23 to -3.90; P < .01) and a higher total difficulties score (β coefficient, 2.62; 95% CI, 0.49-4.76; P < .05).

    Conclusions and relevance: This cohort study found that excessive screen time in early years was associated with poor cognitive and social-emotional development. This finding may be helpful in encouraging awareness among parents of the importance of onset and duration of children's screen time.
  • Zhen, Z., Yang, Z., Huang, L., Kong, X., Wang, X., Dang, X., Huang, Y., Song, Y., & Liu, J. (2015). Quantifying interindividual variability and asymmetry of face-selective regions: A probabilistic functional atlas. NeuroImage, 113, 13-25. doi:10.1016/j.neuroimage.2015.03.010.

    Abstract

    Face-selective regions (FSRs) are among the most widely studied functional regions in the human brain. However, individual variability of the FSRs has not been well quantified. Here we use functional magnetic resonance imaging (fMRI) to localize the FSRs and quantify their spatial and functional variabilities in 202 healthy adults. The occipital face area (OFA), posterior and anterior fusiform face areas (pFFA and aFFA), posterior continuation of the superior temporal sulcus (pcSTS), and posterior and anterior STS (pSTS and aSTS) were delineated for each individual with a semi-automated procedure. A probabilistic atlas was constructed to characterize their interindividual variability, revealing that the FSRs were highly variable in location and extent across subjects. The variability of FSRs was further quantified on both functional (i.e., face selectivity) and spatial (i.e., volume, location of peak activation, and anatomical location) features. Considerable interindividual variability and rightward asymmetry were found in all FSRs on these features. Taken together, our work presents the first effort to characterize comprehensively the variability of FSRs in a large sample of healthy subjects, and invites future work on the origin of the variability and its relation to individual differences in behavioral performance. Moreover, the probabilistic functional atlas will provide an adequate spatial reference for mapping the face network.
  • Zhou, W. (2015). Assessing birth language memory in young adoptees. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Zimianiti, E. (2022). Is semantic memory the winning component in second language teaching with Accelerative Integrated Method (AIM)? LingUU Journal, 6(1), 54-62.

    Abstract

    This paper constitutes a research proposal based on Rousse-Malpalt’s
    (2019) dissertation, which extensively examines the effectiveness of the
    Accelerative Integrated Method (AIM) in second language (L2) learning.
    Although it has been found that AIM is a greatly effective method in comparison with non-implicit teaching methods, the reasons behind its success and effectiveness are yet unknown. As Semantic Memory (SM) is the component of memory responsible for the conceptualization and storage of knowledge, this paper sets to propose an investigation of its role in the learning process of AIM and provide with insights as to why the embodied experience of learning with AIM is more effective than others. The tasks proposed for administration take into account the factors of gestures being related to a learner’s memorization process and Semantic Memory. Lastly, this paper provides with a future research idea about the learning mechanisms of sign languages in people with hearing deficits and healthy population, aiming to indicate which brain mechanisms benefit from the teaching method of AIM and reveal important brain functions for SLA via AIM.
  • Zinn, C., Cablitz, G., Ringersma, J., Kemps-Snijders, M., & Wittenburg, P. (2008). Constructing knowledge spaces from linguistic resources. In Proceedings of the CIL 18 Workshop on Linguistic Studies of Ontology: From lexical semantics to formal ontologies and back.
  • Zinn, C. (2008). Conceptual spaces in ViCoS. In S. Bechhofer, M. Hauswirth, J. Hoffmann, & M. Koubarakis (Eds.), The semantic web: Research and applications (pp. 890-894). Berlin: Springer.

    Abstract

    We describe ViCoS, a tool for constructing and visualising conceptual spaces in the area of language documentation. ViCoS allows users to enrich existing lexical information about the words of a language with conceptual knowledge. Their work towards language-based, informal ontology building must be supported by easy-to-use workflows and supporting software, which we will demonstrate.
  • Zora, H., Schwarz, I.-C., & Heldner, M. (2015). Neural correlates of lexical stress: Mismatch negativity reflects fundamental frequency and intensity. NeuroReport, 26(13), 791-796. doi:10.1097/WNR.0000000000000426.

    Abstract

    Neural correlates of lexical stress were studied using the mismatch negativity (MMN) component in event-related potentials. The MMN responses were expected to reveal the encoding of stress information into long-term memory and the contributions of prosodic features such as fundamental frequency (F0) and intensity toward lexical access. In a passive oddball paradigm, neural responses to changes in F0, intensity, and in both features together were recorded for words and pseudowords. The findings showed significant differences not only between words and pseudowords but also between prosodic features. Early processing of prosodic information in words was indexed by an intensity-related MMN and an F0-related P200. These effects were stable at right-anterior and mid-anterior regions. At a later latency, MMN responses were recorded for both words and pseudowords at the mid-anterior and posterior regions. The P200 effect observed for F0 at the early latency for words developed into an MMN response. Intensity elicited smaller MMN for pseudowords than for words. Moreover, a larger brain area was recruited for the processing of words than for the processing of pseudowords. These findings suggest earlier and higher sensitivity to prosodic changes in words than in pseudowords, reflecting a language-related process. The present study, therefore, not only establishes neural correlates of lexical stress but also confirms the presence of long-term memory traces for prosodic information in the brain.
  • Zora, H., Gussenhoven, C., Tremblay, A., & Liu, F. (2022). Editorial: Crosstalk between intonation and lexical tones: Linguistic, cognitive and neuroscience perspectives. Frontiers in Psychology, 13: 1101499. doi:10.3389/fpsyg.2022.1101499.

    Abstract

    The interplay between categorical and continuous aspects of the speech signal remains central and yet controversial in the fields of phonetics and phonology. The division between phonological abstractions and phonetic variations has been particularly relevant to the unraveling of diverse communicative functions of pitch in the domain of prosody. Pitch influences vocal communication in two major but fundamentally different ways, and lexical and intonational tones exquisitely capture these functions. Lexical tone contrasts convey lexical meanings as well as derivational meanings at the word level and are grammatically encoded as discrete structures. Intonational tones, on the other hand, signal post-lexical meanings at the phrasal level and typically allow gradient pragmatic variations. Since categorical and gradient uses of pitch are ubiquitous and closely intertwined in their physiological and psychological processes, further research is warranted for a more detailed understanding of their structural and functional characterisations. This Research Topic addresses this matter from a wide range of perspectives, including first and second language acquisition, speech production and perception, structural and functional diversity, and working with distinct languages and experimental measures. In the following, we provide a short overview of the contributions submitted to this topic

    Additional information

    also published as book chapter (2023)
  • Zwitserlood, I., Ozyurek, A., & Perniss, P. M. (2008). Annotation of sign and gesture cross-linguistically. In O. Crasborn, E. Efthimiou, T. Hanke, E. D. Thoutenhoofd, & I. Zwitserlood (Eds.), Construction and Exploitation of Sign Language Corpora. 3rd Workshop on the Representation and Processing of Sign Languages (pp. 185-190). Paris: ELDA.

    Abstract

    This paper discusses the construction of a cross-linguistic, bimodal corpus containing three modes of expression: expressions from two sign languages, speech and gestural expressions in two spoken languages and pantomimic expressions by users of two spoken languages who are requested to convey information without speaking. We discuss some problems and tentative solutions for the annotation of utterances expressing spatial information about referents in these three modes, suggesting a set of comparable codes for the description of both sign and gesture. Furthermore, we discuss the processing of entered annotations in ELAN, e.g. relating descriptive annotations to analytic annotations in all three modes and performing relational searches across annotations on different tiers.
  • Zwitserlood, I. (2008). Grammatica-vertaalmethode en nederlandse gebarentaal. Levende Talen Magazine, 95(5), 28-29.
  • Zwitserlood, I. (2011). Gebruiksgemak van het eerste Nederlandse Gebarentaal woordenboek kan beter [Book review]. Levende Talen Magazine, 4, 46-47.

    Abstract

    Review: User friendliness of the first dictionary of Sign Language of the Netherlands can be improved
  • Zwitserlood, I. (2011). Gevraagd: medewerkers verzorgingshuis met een goede oog-handcoördinatie. Het meten van NGT-vaardigheid. Levende Talen Magazine, 1, 44-46.

    Abstract

    (Needed: staff for residential care home with good eye-hand coordination. Measuring NGT-skills.)
  • Zwitserlood, I. (2008). Morphology below the level of the sign - frozen forms and classifier predicates. In J. Quer (Ed.), Proceedings of the 8th Conference on Theoretical Issues in Sign Language Research (TISLR) (pp. 251-272). Hamburg: Signum Verlag.

    Abstract

    The lexicons of many sign languages hold large proportions of “frozen” forms, viz. signs that are generally considered to have been formed productively (as classifier predicates), but that have diachronically undergone processes of lexicalisation. Nederlandse Gebarentaal (Sign Language of the Netherlands; henceforth: NGT) also has many of these signs (Van der Kooij 2002, Zwitserlood 2003). In contrast to the general view on “frozen” forms, a few researchers claim that these signs may be formed according to productive sign formation rules, notably Brennan (1990) for BSL, and Meir (2001, 2002) for ISL. Following these claims, I suggest an analysis of “frozen” NGT signs as morphologically complex, using the framework of Distributed Morphology. The signs in question are derived in a similar way as classifier predicates; hence their similar form (but diverging characteristics). I will indicate how and why the structure and use of classifier predicates and “frozen” forms differ. Although my analysis focuses on NGT, it may also be applicable to other sign languages.
  • Zwitserlood, I. (2011). Het Corpus NGT en de dagelijkse lespraktijk. Levende Talen Magazine, 6, 46.

    Abstract

    (The Corpus NGT and the daily practice of language teaching)
  • Zwitserlood, I. (2011). Het Corpus NGT en de opleiding leraar/tolk NGT. Levende Talen Magazine, 1, 40-41.

    Abstract

    (The Corpus NGT and teacher NGT/interpreter NGT training)

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