Publications

Displaying 301 - 400 of 1265
  • Enfield, N. J., Brown, P., & De Ruiter, J. (2012). Epistemic dimensions of polar questions: Sentence-final particles in comparative perspective. In J. P. De Ruiter (Ed.), Questions: Formal, functional and interactional perspectives (pp. 193-221). New York: Cambridge University Press.
  • Enfield, N. J. (2012). Diversity disregarded [Review of the book Games primates play: An undercover investigation of the evolution and economics of human relationships by Dario Maestripieri]. Science, 337, 1295-1296. doi:10.1126/science.1225365.
  • Enfield, N. J., & Sidnell, J. (2012). Collateral effects, agency, and systems of language use [Reply to commentators]. Current Anthropology, 53(3), 327-329.
  • Enfield, N. J. (2012). [Review of the book "Language, culture, and mind: Natural constructions and social kinds", by Paul Kockelman]. Language in Society, 41(5), 674-677. doi:10.1017/S004740451200070X.
  • Enfield, N. J. (2013). A ‘Composite Utterances’ approach to meaning. In C. Müller, E. Fricke, S. Ladewig, A. Cienki, D. McNeill, & S. Teßendorf (Eds.), Handbook Body – Language – Communication. Volume 1 (pp. 689-706). Berlin: Mouton de Gruyter.
  • Enfield, N. J. (2007). Encoding three-participant events in the Lao clause. Linguistics, 45(3), 509-538. doi:10.1515/LING.2007.016.

    Abstract

    Any language will have a range of predicates that specify three core participants (e.g. 'put', 'show', 'give'), and will conventionally provide a range of constructional types for the expression of these three participants in a structured single-clause or single-sentence event description. This article examines the clausal encoding of three-participant events in Lao, a Tai language of Southeast Asia. There is no possibility in Lao for expression of three full arguments in the core of a single-verb clause (although it is possible to have a third argument in a noncore slot, marked as oblique with a prepositionlike element). Available alternatives include extraposing an argument using a topic-comment construction, incorporating an argument into the verb phrase, and ellipsing one or more contextually retrievable arguments. A more common strategy is verb serialization, for example, where a threeplace verb (e.g. 'put') is assisted by an additional verb (typically a verb of handling such as 'carry') that provides a slot for the theme argument (e.g. the transferred object in a putting scene). The event construal encoded by this type of structure decomposes the event into a first stage in which the agent comes into control over a theme, and a second in which the agent performs a controlled action (e.g. of transfer) with respect to that theme and a goal (and/or source). The particular set of strategies that Lao offers for encoding three-participant events — notably, topic-comment strategy, ellipsis strategy, serial verb strategy — conform with (and are presumably motivated by) the general typological profile of the language. The typological features of Lao are typical for the mainland Southeast Asia area (isolating, topic-prominent, verb-serializing, widespread nominal ellipsis).
  • Enfield, N. J. (2007). A grammar of Lao. Berlin: Mouton de Gruyter.

    Abstract

    Lao is the national language of Laos, and is also spoken widely in Thailand and Cambodia. It is a tone language of the Tai-Kadai family (Southwestern Tai branch). Lao is an extreme example of the isolating, analytic language type. This book is the most comprehensive grammatical description of Lao to date. It describes and analyses the important structures of the language, including classifiers, sentence-final particles, and serial verb constructions. Special attention is paid to grammatical topics from a semantic, pragmatic, and typological perspective.
  • Enfield, N. J. (2007). [Comment on 'Agency' by Paul Kockelman]. Current Anthropology, 48(3), 392-392. doi:10.1086/512998.
  • Enfield, N. J. (2007). [review of the book Ethnopragmatics: Understanding discourse in cultural context ed. by Cliff Goddard]. Intercultural Pragmatics, 4(3), 419-433. doi:10.1515/IP.2007.021.
  • Enfield, N. J. (2007). Meanings of the unmarked: How 'default' person reference does more than just refer. In N. Enfield, & T. Stivers (Eds.), Person reference in interaction: Linguistic, cultural, and social perspectives (pp. 97-120). Cambridge: Cambridge University Press.
  • Enfield, N. J. (2007). Lao separation verbs and the logic of linguistic event categorization. Cognitive Linguistics, 18(2), 287-296. doi:10.1515/COG.2007.016.

    Abstract

    While there are infinite conceivable events of material separation, those actually encoded in the conventions of a given language's verb semantics number only a few. Furthermore, there appear to be crosslinguistic parallels in the native verbal analysis of this conceptual domain. What are the operative distinctions, and why these? This article analyses a key subset of the bivalent (transitive) verbs of cutting and breaking in Lao. I present a decompositional analysis of the verbs glossed 'cut (off)', 'cut.into.with.placed.blade', 'cut.into.with.moving.blade', and 'snap', pursuing the idea that the attested combinations of sub-events have a natural logic to them. Consideration of the nature of linguistic categories, as distinct from categories in general, suggests that the attested distinctions must have ethnographic and social interactional significance, raising new lines of research for cognitive semantics.
  • Enfield, N. J., Dingemanse, M., Baranova, J., Blythe, J., Brown, P., Dirksmeyer, T., Drew, P., Floyd, S., Gipper, S., Gisladottir, R. S., Hoymann, G., Kendrick, K. H., Levinson, S. C., Magyari, L., Manrique, E., Rossi, G., San Roque, L., & Torreira, F. (2013). Huh? What? – A first survey in 21 languages. In M. Hayashi, G. Raymond, & J. Sidnell (Eds.), Conversational repair and human understanding (pp. 343-380). New York: Cambridge University Press.

    Abstract

    Introduction

    A comparison of conversation in twenty-one languages from around the world reveals commonalities and differences in the way that people do open-class other-initiation of repair (Schegloff, Jefferson, and Sacks, 1977; Drew, 1997). We find that speakers of all of the spoken languages in the sample make use of a primary interjection strategy (in English it is Huh?), where the phonetic form of the interjection is strikingly similar across the languages: a monosyllable featuring an open non-back vowel [a, æ, ə, ʌ], often nasalized, usually with rising intonation and sometimes an [h-] onset. We also find that most of the languages have another strategy for open-class other-initiation of repair, namely the use of a question word (usually “what”). Here we find significantly more variation across the languages. The phonetic form of the question word involved is completely different from language to language: e.g., English [wɑt] versus Cha'palaa [ti] versus Duna [aki]. Furthermore, the grammatical structure in which the repair-initiating question word can or must be expressed varies within and across languages. In this chapter we present data on these two strategies – primary interjections like Huh? and question words like What? – with discussion of possible reasons for the similarities and differences across the languages. We explore some implications for the notion of repair as a system, in the context of research on the typology of language use.

    The general outline of this chapter is as follows. We first discuss repair as a system across languages and then introduce the focus of the chapter: open-class other-initiation of repair. A discussion of the main findings follows, where we identify two alternative strategies in the data: an interjection strategy (Huh?) and a question word strategy (What?). Formal features and possible motivations are discussed for the interjection strategy and the question word strategy in order. A final section discusses bodily behavior including posture, eyebrow movements and eye gaze, both in spoken languages and in a sign language.
  • Enfield, N. J. (2012). Language innateness [Letter to the Editor]. The Times Literary Supplement, October 26, 2012(5717), 6.
  • Enfield, N. J. (2013). Language, culture, and mind: Trends and standards in the latest pendulum swing. Journal of the Royal Anthropological Institute, 19, 155-169. doi:10.1111/1467-9655.12008.

    Abstract

    The study of language in relation to anthropological questions has deep and varied roots, from Humboldt and Boas, Malinowski and Vygotsky, Sapir and Whorf, Wittgenstein and Austin, through to the linguistic anthropologists of now. A recent book by the linguist Daniel Everett, language: the cultural tool (2012), aims to bring some of the issues to a popular audience, with a focus on the idea that language is a tool for social action. I argue in this essay that the book does not represent the state of the art in this field, falling short on three central desiderata of a good account for the social functions of language and its relation to culture. I frame these desiderata in terms of three questions, here termed the cognition question, the causality question, and the culture question. I look at the relevance of this work for socio-cultural anthropology, in the context of a major interdisciplinary pendulum swing that is incipient in the study of language today, a swing away from formalist, innatist perspectives, and towards functionalist, empiricist perspectives. The role of human diversity and culture is foregrounded in all of this work. To that extent, Everett’s book is representative, but the quality of his argument is neither strong in itself nor representative of a movement that ought to be of special interest to socio-cultural anthropologists.
  • Enfield, N. J. (2013). Hippie, interrupted. In J. Barker, & J. Lindquist (Eds.), Figures of Southeast Asian modernity (pp. 101-103). Honolulu: University of Hawaii Press.
  • Enfield, N. J. (2013). Reference in conversation. In J. Sidnell, & T. Stivers (Eds.), The handbook of conversation analysis (pp. 433-454). Malden, MA: Wiley-Blackwell. doi:10.1002/9781118325001.ch21.

    Abstract

    This chapter contains sections titled: Introduction Lexical Selection in Reference: Introductory Examples of Reference to Times Multiple “Preferences” Future Directions Conclusion
  • Enfield, N. J. (2013). Rejoinder to Daniel Everett [Comment]. Journal of the Royal Anthropological Institute, 19(3), 649. doi:10.1111/1467-9655.12056.
  • Enfield, N. J. (2013). Relationship thinking: Agency, enchrony, and human sociality. New York: Oxford University Press.
  • Enfield, N. J. (2007). Repair sequences in interaction. In A. Majid (Ed.), Field Manual Volume 10 (pp. 100-103). Nijmegen: Max Planck Institute for Psycholinguistics. doi:10.17617/2.468724.

    Abstract

    This sub-project is concerned with analysis and cross-linguistic comparison of the mechanisms of signaling and redressing ‘trouble’ during conversation. Speakers and listeners constantly face difficulties with many different aspects of speech production and comprehension during conversation. A speaker may mispronounce a word, or may be unable to find a word, or be unable to formulate in words an idea he or she has in mind. A listener may have troubling hearing (part of) what was said, may not know who a speaker is referring to, may not be sure of the current relevance of what is being said. There may be problems in the organisation of turns at talk, for instance, two speakers’ speech may be in overlap. The goal of this task is to investigate the range of practices that a language uses to address problems of speaking, hearing and understanding in conversation.
  • Enfield, N. J. (2012). The slow explosion of speech [Review of the book The origins of Grammar by James R. Hurford]. The Times Literary Supplement, March 30, 2012(5687), 11-12. Retrieved from http://www.the-tls.co.uk/tls/public/article1004404.ece.

    Abstract

    Book review of James R. Hurford THE ORIGINS OF GRAMMAR 791pp. Oxford University Press. ISBN 978 0 19 920787 9
  • Enfield, N. J. (2013). The virtual you and the real you [Book review]. The Times Literary Supplement, April 12, 2013(5741), 31-32.

    Abstract

    Review of the books "Virtually you. The dangerous powers of the e-personality", by Elias Aboujaoude; "The big disconnect. The story of technology and loneliness", by Giles Slade; and "Net smart. How to thrive online", by Howard Rheingold.
  • Erb, J., Henry, M. J., Eisner, F., & Obleser, J. (2012). Auditory skills and brain morphology predict individual differences in adaptation to degraded speech. Neuropsychologia, 50, 2154-2164. doi:10.1016/j.neuropsychologia.2012.05.013.

    Abstract

    Noise-vocoded speech is a spectrally highly degraded signal, but it preserves the temporal envelope of speech. Listeners vary considerably in their ability to adapt to this degraded speech signal. Here, we hypothesized that individual differences in adaptation to vocoded speech should be predictable by non-speech auditory, cognitive, and neuroanatomical factors. We tested eighteen normal-hearing participants in a short-term vocoded speech-learning paradigm (listening to 100 4-band-vocoded sentences). Non-speech auditory skills were assessed using amplitude modulation (AM) rate discrimination, where modulation rates were centered on the speech-relevant rate of 4 Hz. Working memory capacities were evaluated (digit span and nonword repetition), and structural MRI scans were examined for anatomical predictors of vocoded speech learning using voxel-based morphometry. Listeners who learned faster to understand degraded speech also showed smaller thresholds in the AM discrimination task. This ability to adjust to degraded speech is furthermore reflected anatomically in increased volume in an area of the left thalamus (pulvinar) that is strongly connected to the auditory and prefrontal cortices. Thus, individual non-speech auditory skills and left thalamus grey matter volume can predict how quickly a listener adapts to degraded speech.
  • Erb, J., Henry, M. J., Eisner, F., & Obleser, J. (2013). The brain dynamics of rapid perceptual adaptation to adverse listening conditions. The Journal of Neuroscience, 33, 10688-10697. doi:10.1523/​JNEUROSCI.4596-12.2013.

    Abstract

    Listeners show a remarkable ability to quickly adjust to degraded speech input. Here, we aimed to identify the neural mechanisms of such short-term perceptual adaptation. In a sparse-sampling, cardiac-gated functional magnetic resonance imaging (fMRI) acquisition, human listeners heard and repeated back 4-band-vocoded sentences (in which the temporal envelope of the acoustic signal is preserved, while spectral information is highly degraded). Clear-speech trials were included as baseline. An additional fMRI experiment on amplitude modulation rate discrimination quantified the convergence of neural mechanisms that subserve coping with challenging listening conditions for speech and non-speech. First, the degraded speech task revealed an “executive” network (comprising the anterior insula and anterior cingulate cortex), parts of which were also activated in the non-speech discrimination task. Second, trial-by-trial fluctuations in successful comprehension of degraded speech drove hemodynamic signal change in classic “language” areas (bilateral temporal cortices). Third, as listeners perceptually adapted to degraded speech, downregulation in a cortico-striato-thalamo-cortical circuit was observable. The present data highlight differential upregulation and downregulation in auditory–language and executive networks, respectively, with important subcortical contributions when successfully adapting to a challenging listening situation.
  • Ernestus, M., Van Mulken, M., & Baayen, R. H. (2007). Ridders en heiligen in tijd en ruimte: Moderne stylometrische technieken toegepast op Oud-Franse teksten. Taal en Tongval, 58, 1-83.

    Abstract

    This article shows that Old-French literary texts differ systematically in their relative frequencies of syntactic constructions. These frequencies reflect differences in register (poetry versus prose), region (Picardy, Champagne, and Esatern France), time period (until 1250, 1251 – 1300, 1301 – 1350), and genre (hagiography, romance of chivalry, or other).
  • Ernestus, M., & Baayen, R. H. (2007). Paradigmatic effects in auditory word recognition: The case of alternating voice in Dutch. Language and Cognitive Processes, 22(1), 1-24. doi:10.1080/01690960500268303.

    Abstract

    Two lexical decision experiments addressed the role of paradigmatic effects in auditory word recognition. Experiment 1 showed that listeners classified a form with an incorrectly voiced final obstruent more readily as a word if the obstruent is realised as voiced in other forms of that word's morphological paradigm. Moreover, if such was the case, the exact probability of paradigmatic voicing emerged as a significant predictor of the response latencies. A greater probability of voicing correlated with longer response latencies for words correctly realised with voiceless final obstruents. A similar effect of this probability was observed in Experiment 2 for words with completely voiceless or weakly voiced (incompletely neutralised) final obstruents. These data demonstrate the relevance of paradigmatically related complex words for the processing of morphologically simple words in auditory word recognition.
  • Ernestus, M., & Baayen, R. H. (2007). The comprehension of acoustically reduced morphologically complex words: The roles of deletion, duration, and frequency of occurence. In J. Trouvain, & W. J. Barry (Eds.), Proceedings of the 16th International Congress of Phonetic Sciences (ICPhs 2007) (pp. 773-776). Dudweiler: Pirrot.

    Abstract

    This study addresses the roles of segment deletion, durational reduction, and frequency of use in the comprehension of morphologically complex words. We report two auditory lexical decision experiments with reduced and unreduced prefixed Dutch words. We found that segment deletions as such delayed comprehension. Simultaneously, however, longer durations of the different parts of the words appeared to increase lexical competition, either from the word’s stem (Experiment 1) or from the word’s morphological continuation forms (Experiment 2). Increased lexical competition slowed down especially the comprehension of low frequency words, which shows that speakers do not try to meet listeners’ needs when they reduce especially high frequency words.
  • Ernestus, M., & Baayen, R. H. (2007). Intraparadigmatic effects on the perception of voice. In J. van de Weijer, & E. J. van der Torre (Eds.), Voicing in Dutch: (De)voicing-phonology, phonetics, and psycholinguistics (pp. 153-173). Amsterdam: Benjamins.

    Abstract

    In Dutch, all morpheme-final obstruents are voiceless in word-final position. As a consequence, the distinction between obstruents that are voiced before vowel-initial suffixes and those that are always voiceless is neutralized. This study adds to the existing evidence that the neutralization is incomplete: neutralized, alternating plosives tend to have shorter bursts than non-alternating plosives. Furthermore, in a rating study, listeners scored the alternating plosives as more voiced than the nonalternating plosives, showing sensitivity to the subtle subphonemic cues in the acoustic signal. Importantly, the participants who were presented with the complete words, instead of just the final rhymes, scored the alternating plosives as even more voiced. This shows that listeners’ perception of voice is affected by their knowledge of the obstruent’s realization in the word’s morphological paradigm. Apparently, subphonemic paradigmatic levelling is a characteristic of both production and perception. We explain the effects within an analogy-based approach.
  • Ernestus, M. (2013). Halve woorden [Inaugural lecture]. Nijmegen: Radboud University.

    Abstract

    Rede uitgesproken bij de aanvaarding van het ambt van hoogleraar Psycholinguïstiek aan de Faculteit der Letteren van de Radboud Universiteit Nijmegen op vrijdag 18 januari 2013
  • Ernestus, M. (2012). Segmental within-speaker variation. In A. C. Cohn, C. Fougeron, & M. K. Huffman (Eds.), The Oxford handbook of laboratory phonology (pp. 93-102). New York: Oxford University Press.
  • Escudero, P., Broersma, M., & Simon, E. (2013). Learning words in a third language: Effects of vowel inventory and language proficiency. Language and Cognitive Processes, 28, 746-761. doi:10.1080/01690965.2012.662279.

    Abstract

    This study examines the effect of L2 and L3 proficiency on L3 word learning. Native speakers of Spanish with different proficiencies in L2 English and L3 Dutch and a control group of Dutch native speakers participated in a Dutch word learning task involving minimal and non-minimal word pairs. The minimal word pairs were divided into ‘minimal-easy’ and ‘minimal-difficult’ pairs on the basis of whether or not they are known to pose perceptual problems for L1 Spanish learners. Spanish speakers’ proficiency in Dutch and English was independently established by their scores on general language comprehension tests. All participants were trained and subsequently tested on the mapping between pseudo-words and non-objects. The results revealed that, first, both native and non-native speakers produced more errors and longer reaction times for minimal than for non-minimal word pairs, and secondly, Spanish learners had more errors and longer reaction times for minimal-difficult than for minimal-easy pairs. The latter finding suggests that there is a strong continuity between sound perception and L3 word recognition. With respect to proficiency, only the learner’s proficiency in their L2, namely English, predicted their accuracy on L3 minimal pairs. This shows that learning an L2 with a larger vowel inventory than the L1 is also beneficial for word learning in an L3 with a similarly large vowel inventory.

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  • Escudero, P., Simon, E., & Mitterer, H. (2012). The perception of English front vowels by North Holland and Flemish listeners: Acoustic similarity predicts and explains cross-linguistic and L2 perception. Journal of Phonetics, 40, 280-288. doi:10.1016/j.wocn.2011.11.004.

    Abstract

    We investigated whether regional differences in the native language (L1) influence the perception of second language (L2) sounds. Many cross-language and L2 perception studies have assumed that the degree of acoustic similarity between L1 and L2 sounds predicts cross-linguistic and L2 performance. The present study tests this assumption by examining the perception of the English contrast between /e{open}/ and /æ/ in native speakers of Dutch spoken in North Holland (the Netherlands) and in East- and West-Flanders (Belgium). A Linear Discriminant Analysis on acoustic data from both dialects showed that their differences in vowel production, as reported in and Adank, van Hout, and Van de Velde (2007), should influence the perception of the L2 vowels if listeners focus on the vowels' acoustic/auditory properties. Indeed, the results of categorization tasks with Dutch or English vowels as response options showed that the two listener groups differed as predicted by the discriminant analysis. Moreover, the results of the English categorization task revealed that both groups of Dutch listeners displayed the asymmetric pattern found in previous word recognition studies, i.e. English /æ/ was more frequently confused with English /e{open}/ than the reverse. This suggests a strong link between previous L2 word learning results and the present L2 perceptual assimilation patterns.
  • Essegbey, J., & Ameka, F. K. (2007). "Cut" and "break" verbs in Gbe and Sranan. Journal of Pidgin and Creole Languages, 22(1), 37-55. doi:10.1075/jpcl.22.1.04ess.

    Abstract

    This paper compares “cut” and “break” verbs in four variants of Gbe, namely Anfoe, Anlo, Fon and Ayizo, with those of Sranan. “Cut” verbs are change-of-state verbs that co-lexicalize the type of action that brings about a change, the type of instrument or instrument part, and the manner in which a change occurs. By contrast, break verbs co-lexicalize either the type of object or the type of change. It has been hypothesized that “cut”-verbs are unergative while breaks verbs are unaccusatives. For example “break” verbs participate in the causative alternation constructions but “cut” verbs don’t. We show that although there are some differences in the meanings of “cut” and break verbs across the Gbe languages, significant generalizations can be made with regard to their lexicalization patterns. By contrast, the meanings of “cut” and break verbs in Sranan are closer to those of their etymons in English and Dutch. However, despite the differences in the meanings of “cut” and “break” verbs between the Gbe languages and Sranan, the syntax of the verbs in Sranan is similar to that of the Eastern Gbe variants, namely Fon and Ayizo. We look at the implications of our findings for the relexification hypothesis. (copyright Benjamins)
  • Estruch, S. B., Buzon, V., Carbo, L. R., Schorova, L., Luders, J., & Estebanez-Perpina, E. (2012). The oncoprotein BCL11A binds to Orphan Nuclear Receptor TLX and potentiates its transrepressive function. PLoS One, 7(6): e37963. doi:10.1371/journal.pone.0037963.

    Abstract

    Nuclear orphan receptor TLX (NR2E1) functions primarily as a transcriptional repressor and its pivotal role in brain development, glioblastoma, mental retardation and retinopathologies make it an attractive drug target. TLX is expressed in the neural stem cells (NSCs) of the subventricular zone and the hippocampus subgranular zone, regions with persistent neurogenesis in the adult brain, and functions as an essential regulator of NSCs maintenance and self-renewal. Little is known about the TLX social network of interactors and only few TLX coregulators are described. To identify and characterize novel TLX-binders and possible coregulators, we performed yeast-two-hybrid (Y2H) screens of a human adult brain cDNA library using different TLX constructs as baits. Our screens identified multiple clones of Atrophin-1 (ATN1), a previously described TLX interactor. In addition, we identified an interaction with the oncoprotein and zinc finger transcription factor BCL11A (CTIP1/Evi9), a key player in the hematopoietic system and in major blood-related malignancies. This interaction was validated by expression and coimmunoprecipitation in human cells. BCL11A potentiated the transrepressive function of TLX in an in vitro reporter gene assay. Our work suggests that BCL11A is a novel TLX coregulator that might be involved in TLX-dependent gene regulation in the brain.
  • Evans, D. M., Zhu, G., Dy, V., Heath, A. C., Madden, P. A. F., Kemp, J. P., McMahon, G., St Pourcain, B., Timpson, N. J., Golding, J., Lawlor, D. A., Steer, C., Montgomery, G. W., Martin, N. G., Smith, G. D., & Whitfield, J. B. (2013). Genome-wide association study identifies loci affecting blood copper, selenium and zinc. Human Molecular Genetics, 22(19), 3998-4006. doi:10.1093/hmg/ddt239.

    Abstract

    Genetic variation affecting absorption, distribution or excretion of essential trace elements may lead to health effects related to sub-clinical deficiency. We have tested for allelic effects of single-nucleotide polymorphisms (SNPs) on blood copper, selenium and zinc in a genome-wide association study using two adult cohorts from Australia and the UK. Participants were recruited in Australia from twins and their families and in the UK from pregnant women. We measured erythrocyte Cu, Se and Zn (Australian samples) or whole blood Se (UK samples) using inductively coupled plasma mass spectrometry. Genotyping was performed with Illumina chips and > 2.5 m SNPs were imputed from HapMap data. Genome-wide significant associations were found for each element. For Cu, there were two loci on chromosome 1 (most significant SNPs rs1175550, P = 5.03 × 10(-10), and rs2769264, P = 2.63 × 10(-20)); for Se, a locus on chromosome 5 was significant in both cohorts (combined P = 9.40 × 10(-28) at rs921943); and for Zn three loci on chromosomes 8, 15 and X showed significant results (rs1532423, P = 6.40 × 10(-12); rs2120019, P = 1.55 × 10(-18); and rs4826508, P = 1.40 × 10(-12), respectively). The Se locus covers three genes involved in metabolism of sulphur-containing amino acids and potentially of the analogous Se compounds; the chromosome 8 locus for Zn contains multiple genes for the Zn-containing enzyme carbonic anhydrase. Where potentially relevant genes were identified, they relate to metabolism of the element (Se) or to the presence at high concentration of a metal-containing protein (Cu).
  • Evans, D. M., Brion, M. J. A., Paternoster, L., Kemp, J. P., McMahon, G., Munafò, M., Whitfield, J. B., Medland, S. E., Montgomery, G. W., Timpson, N. J., St Pourcain, B., Lawlor, D. A., Martin, N. G., Dehghan, A., Hirschhorn, J., Davey Smith, G., The GIANT consortium, The CRP consortium, & The TAG Consortium (2013). Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates. PLoS Genet, 9(10): e1003919. doi:10.1371/journal.pgen.1003919.

    Abstract

    Author SummaryThe standard approach in genome-wide association studies is to analyse the relationship between genetic variants and disease one marker at a time. Significant associations between markers and disease are then used as evidence to implicate biological intermediates and pathways likely to be involved in disease aetiology. However, single genetic variants typically only explain small amounts of disease risk. Our idea is to construct allelic scores that explain greater proportions of the variance in biological intermediates than single markers, and then use these scores to data mine genome-wide association studies. We show how allelic scores derived from known variants as well as allelic scores derived from hundreds of thousands of genetic markers across the genome explain significant portions of the variance in body mass index, levels of C-reactive protein, and LDLc cholesterol, and many of these scores show expected correlations with disease. Power calculations confirm the feasibility of scaling our strategy to the analysis of tens of thousands of molecular phenotypes in large genome-wide meta-analyses. Our method represents a simple way in which tens of thousands of molecular phenotypes could be screened for potential causal relationships with disease.
  • Fahrenfort, J. J., Snijders, T. M., Heinen, K., van Gaal, S., & Scholte, H. S. (2012). Neuronal integration in visual cortex elevates face category tuning to conscious face perception. Proceedings of the National Academy of Sciences of the United States of America, 109(52), 21504-21509. doi:10.1073/pnas.1207414110.
  • Fatemifar, G., Hoggart, C. J., Paternoster, L., Kemp, J. P., Prokopenko, I., Horikoshi, M., Wright, V. J., Tobias, J. H., Richmond, S., Zhurov, A. I., Toma, A. M., Pouta, A., Taanila, A., Sipila, K., Lähdesmäki, R., Pillas, D., Geller, F., Feenstra, B., Melbye, M., Nohr, E. A. and 6 moreFatemifar, G., Hoggart, C. J., Paternoster, L., Kemp, J. P., Prokopenko, I., Horikoshi, M., Wright, V. J., Tobias, J. H., Richmond, S., Zhurov, A. I., Toma, A. M., Pouta, A., Taanila, A., Sipila, K., Lähdesmäki, R., Pillas, D., Geller, F., Feenstra, B., Melbye, M., Nohr, E. A., Ring, S. M., St Pourcain, B., Timpson, N. J., Davey Smith, G., Jarvelin, M.-R., & Evans, D. M. (2013). Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances. Human Molecular Genetics, 22(18), 3807-3817. doi:10.1093/hmg/ddt231.

    Abstract

    Twin and family studies indicate that the timing of primary tooth eruption is highly heritable, with estimates typically exceeding 80%. To identify variants involved in primary tooth eruption, we performed a population-based genome-wide association study of 'age at first tooth' and 'number of teeth' using 5998 and 6609 individuals, respectively, from the Avon Longitudinal Study of Parents and Children (ALSPAC) and 5403 individuals from the 1966 Northern Finland Birth Cohort (NFBC1966). We tested 2 446 724 SNPs imputed in both studies. Analyses were controlled for the effect of gestational age, sex and age of measurement. Results from the two studies were combined using fixed effects inverse variance meta-analysis. We identified a total of 15 independent loci, with 10 loci reaching genome-wide significance (P < 5 × 10(-8)) for 'age at first tooth' and 11 loci for 'number of teeth'. Together, these associations explain 6.06% of the variation in 'age of first tooth' and 4.76% of the variation in 'number of teeth'. The identified loci included eight previously unidentified loci, some containing genes known to play a role in tooth and other developmental pathways, including an SNP in the protein-coding region of BMP4 (rs17563, P = 9.080 × 10(-17)). Three of these loci, containing the genes HMGA2, AJUBA and ADK, also showed evidence of association with craniofacial distances, particularly those indexing facial width. Our results suggest that the genome-wide association approach is a powerful strategy for detecting variants involved in tooth eruption, and potentially craniofacial growth and more generally organ development.
  • Fawcett, C., & Liszkowski, U. (2012). Infants anticipate others’ social preferences. Infant and Child Development, 21, 239-249. doi:10.1002/icd.739.

    Abstract

    In the current eye-tracking study, we explored whether 12-month-old infants can predict others' social preferences. We showed infants scenes in which two characters alternately helped or hindered an agent in his goal of climbing a hill. In a control condition, the two characters moved up and down the hill in identical ways to the helper and hinderer but did not make contact with the agent; thus, they did not cause him to reach or not reach her or his goal. Following six alternating familiarization trials of helping and hindering interactions (help-hinder condition) or up and down interactions (up-down condition), infants were shown one test trial in which they could visually anticipate the agent approaching one of the two characters. As predicted, infants in the help-hinder condition made significantly more visual anticipations toward the helping than hindering character, suggesting that they predicted the agent to approach the helping character. In contrast, infants revealed no difference in visual anticipations between the up and down characters. The up-down condition served to control for low-level perceptual explanations of the results for the help-hinder condition. Thus, together the results reveal that 12-month-old infants make predictions about others' behaviour and social preferences from a third-party perspective.
  • Fawcett, C., & Liszkowski, U. (2012). Mimicry and play initiation in 18-month-old infants. Infant Behavior and Development, 35, 689-696. doi:10.1016/j.infbeh.2012.07.014.

    Abstract

    Across two experiments, we examined the relationship between 18-month-old infants’ mimicry and social behavior – particularly invitations to play with an adult play partner. In Experiment 1, we manipulated whether an adult mimicked the infant's play or not during an initial play phase. We found that infants who had been mimicked were subsequently more likely to invite the adult to join their play with a new toy. In addition, they reenacted marginally more steps from a social learning demonstration she gave. In Experiment 2, infants had the chance to spontaneously mimic the adult during the play phase. Complementing Experiment 1, those infants who spent more time mimicking the adult were more likely to invite her to play with a new toy. This effect was specific to play and not apparent in other communicative acts, such as directing the adult's attention to an event or requesting toys. Together, the results suggest that infants use mimicry as a tool to establish social connections with others and that mimicry has specific influences on social behaviors related to initiating subsequent joint interactions.
  • Fawcett, C., & Liszkowski, U. (2012). Observation and initiation of joint action in infants. Child Development, 83, 434-441. doi:10.1111/j.1467-8624.2011.01717.x.

    Abstract

    Infants imitate others’ individual actions, but do they also replicate others’ joint activities? To examine whether observing joint action influences infants’ initiation of joint action, forty-eight 18-month-old infants observed object demonstrations by 2 models acting together (joint action), 2 models acting individually (individual action), or 1 model acting alone (solitary action). Infants’ behavior was examined after they were given each object. Infants in the joint action condition attempted to initiate joint action more often than infants in the other conditions, yet they were equally likely to communicate for other reasons and to imitate the demonstrated object-directed actions. The findings suggest that infants learn to replicate others’ joint activity through observation, an important skill for cultural transmission of shared practices.
  • Fear, B. D., Cutler, A., & Butterfield, S. (1995). The strong/weak syllable distinction in English. Journal of the Acoustical Society of America, 97, 1893-1904. doi:10.1121/1.412063.

    Abstract

    Strong and weak syllables in English can be distinguished on the basis of vowel quality, of stress, or of both factors. Critical for deciding between these factors are syllables containing unstressed unreduced vowels, such as the first syllable of automata. In this study 12 speakers produced sentences containing matched sets of words with initial vowels ranging from stressed to reduced, at normal and at fast speech rates. Measurements of the duration, intensity, F0, and spectral characteristics of the word-initial vowels showed that unstressed unreduced vowels differed significantly from both stressed and reduced vowels. This result held true across speaker sex and dialect. The vowels produced by one speaker were then cross-spliced across the words within each set, and the resulting words' acceptability was rated by listeners. In general, cross-spliced words were only rated significantly less acceptable than unspliced words when reduced vowels interchanged with any other vowel. Correlations between rated acceptability and acoustic characteristics of the cross-spliced words demonstrated that listeners were attending to duration, intensity, and spectral characteristics. Together these results suggest that unstressed unreduced vowels in English pattern differently from both stressed and reduced vowels, so that no acoustic support for a binary categorical distinction exists; nevertheless, listeners make such a distinction, grouping unstressed unreduced vowels by preference with stressed vowels
  • Fedden, S., & Boroditsky, L. (2012). Spatialization of time in Mian. Frontiers in Psychology, 3, 485. doi:10.3389/fpsyg.2012.00485.

    Abstract

    We examine representations of time among the Mianmin of Papua New Guinea. We begin by describing the patterns of spatial and temporal reference in Mian. Mian uses a system of spatial terms that derive from the orientation and direction of the Hak and Sek rivers and the surrounding landscape. We then report results from a temporal arrangement task administered to a group of Mian speakers. The results reveal evidence for a variety of temporal representations. Some participants arranged time with respect to their bodies (left to right or toward the body). Others arranged time as laid out on the landscape, roughly along the east/west axis (either east to west or west to east). This absolute pattern is consistent both with the axis of the motion of the sun and the orientation of the two rivers, which provides the basis for spatial reference in the Mian language. The results also suggest an increase in left-to-right temporal representations with increasing years of formal education (and the reverse pattern for absolute spatial representations for time). These results extend previous work on spatial representations for time to a new geographical region, physical environment, and linguistic and cultural system.
  • Felser, C., & Roberts, L. (2007). Processing wh-dependencies in a second language: A cross-modal priming study. Second Language Research, 23(1), 9-36. doi:10.1177/0267658307071600.

    Abstract

    This study investigates the real-time processing of wh-dependencies by advanced Greek-speaking learners of English using a cross-modal picture priming task. Participants were asked to respond to different types of picture target presented either at structurally defined gap positions, or at pre-gap control positions, while listening to sentences containing indirect-object relative clauses. Our results indicate that the learners processed the experimental sentences differently from both adult native speakers of English and monolingual English-speaking children. Contrary to what has been found for native speakers, the learners' response pattern was not influenced by individual working memory differences. Adult second language learners differed from native speakers with a relatively high reading or listening span in that they did not show any evidence of structurally based antecedent reactivation at the point of the indirect object gap. They also differed from low-span native speakers, however, in that they showed evidence of maintained antecedent activation during the processing of the experimental sentences. Whereas the localized priming effect observed in the high-span controls is indicative of trace-based antecedent reactivation in native sentence processing, the results from the Greek-speaking learners support the hypothesis that the mental representations built during non-native language processing lack abstract linguistic structure such as movement traces.
  • Ferreri, A., Ponzoni, M., Govi, S., Pasini, E., Mappa, S., Vino, A., Facchetti, F., Vezzoli, P., Doglioni, C., Berti, E., & Dolcetti, R. (2012). Prevalence of chlamydial infection in a series of 108 primary cutaneous lymphomas. British Journal of Dermatology, 166(5), 1121-1123. doi:10.1111/j.1365-2133.2011.10704.x.
  • Fessler, D. M., Stieger, S., Asaridou, S. S., Bahia, U., Cravalho, M., de Barros, P., Delgado, T., Fisher, M. L., Frederick, D., Perez, P. G., Goetz, C., Haley, K., Jackson, J., Kushnick, G., Lew, K., Pain, E., Florindo, P. P., Pisor, A., Sinaga, E., Sinaga, L. and 3 moreFessler, D. M., Stieger, S., Asaridou, S. S., Bahia, U., Cravalho, M., de Barros, P., Delgado, T., Fisher, M. L., Frederick, D., Perez, P. G., Goetz, C., Haley, K., Jackson, J., Kushnick, G., Lew, K., Pain, E., Florindo, P. P., Pisor, A., Sinaga, E., Sinaga, L., Smolich, L., Sun, D. M., & Voracek, M. (2012). Testing a postulated case of intersexual selection in humans: The role of foot size in judgments of physical attractiveness and age. Evolution and Human Behavior, 33, 147-164. doi:10.1016/j.evolhumbehav.2011.08.002.

    Abstract

    The constituents of attractiveness differ across the sexes. Many relevant traits are dimorphic, suggesting that they are the product of intersexual selection. However, direction of causality is generally difficult to determine, as aesthetic criteria can as readily result from, as cause, dimorphism. Women have proportionately smaller feet than men. Prior work on the role of foot size in attractiveness suggests an asymmetry across the sexes, as small feet enhance female appearance, yet average, rather than large, feet are preferred on men. Previous investigations employed crude stimuli and limited samples. Here, we report on multiple cross-cultural studies designed to overcome these limitations. With the exception of one rural society, we find that small foot size is preferred when judging women, yet no equivalent preference applies to men. Similarly, consonant with the thesis that a preference for youth underlies intersexual selection acting on women, we document an inverse relationship between foot size and perceived age. Examination of preferences regarding, and inferences from, feet viewed in isolation suggests different roles for proportionality and absolute size in judgments of female and male bodies. Although the majority of these results bolster the conclusion that pedal dimorphism is the product of intersexual selection, the picture is complicated by the reversal of the usual preference for small female feet found in one rural society. While possibly explicable in terms of greater emphasis on female economic productivity relative to beauty, the latter finding underscores the importance of employing diverse samples when exploring postulated evolved aesthetic preferences.

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  • Filippi, P. (2013). Connessioni regolate: la chiave ontologica alle specie-specificità? Epekeina, 2(1), 203-223. doi:10.7408/epkn.epkn.v2i1.41.

    Abstract

    This article focuses on “perceptual syntax”, the faculty to process patterns in sensory stimuli. Specifically, this study addresses the ability to perceptually connect elements that are: (1) of the same sensory modality; (2) spatially and temporally non-adjacent; or (3) within multiple sensorial domains. The underlying hypothesis is that in each animal species, this core cognitive faculty enables the perception of the environment-world (Umwelt) and consequently the possibility to survive within it. Importantly, it is suggested that in doing so, perceptual syntax determines (and guides) each species’ ontological access to the world. In support of this hypothesis, research on perceptual syntax in nonverbal individuals (preverbal infants and nonhuman animals) and humans is reviewed. This comparative approach results in theoretical remarks on human cognition and ontology, pointing to the conclusion that the ability to map cross-modal connections through verbal language is what makes humans’ form of life species-typical.
  • Filippi, P., Charlton, B. D., & Fitch, W. T. (2012). Do Women Prefer More Complex Music around Ovulation? PLoS One, 7(4): e35626. doi:10.1371/journal.pone.0035626.

    Abstract

    The evolutionary origins of music are much debated. One theory holds that the ability to produce complex musical sounds might reflect qualities that are relevant in mate choice contexts and hence, that music is functionally analogous to the sexually-selected acoustic displays of some animals. If so, women may be expected to show heightened preferences for more complex music when they are most fertile. Here, we used computer-generated musical pieces and ovulation predictor kits to test this hypothesis. Our results indicate that women prefer more complex music in general; however, we found no evidence that their preference for more complex music increased around ovulation. Consequently, our findings are not consistent with the hypothesis that a heightened preference/bias in women for more complex music around ovulation could have played a role in the evolution of music. We go on to suggest future studies that could further investigate whether sexual selection played a role in the evolution of this universal aspect of human culture.
  • Filippi, P. (2012). Sintassi, Prosodia e Socialità: le Origini del Linguaggio Verbale. PhD Thesis, Università degli Studi di Palermo, Palermo.

    Abstract

    What is the key cognitive ability that makes humans unique among all the other animals? Our work aims at contributing to this research question adopting a comparative and philosophical approach to the origins of verbal language. In particular, we adopt three strands of analysis that are relevant in the context of comparative investigation on the the origins of verbal language: a) research on the evolutionary ‘homologies’, which provides information on the phylogenetic traits that humans and other primates share with their common ancestor; b) investigations on “analogous” traits, aimed at finding the evolutionary pressures that guided the emergence of the same biological traits that evolved independently in phylogenetically distant species; the ontogenetic development of the ability to produce and understand verbal language in human infants. Within this comparative approach, we focus on three key apsects that we addressed bridging recent empiric evidence on language processing with philosophical investigations on verbal language: (i) pattern processing as a biologocal precursor of syntax and algebraic rule acquisition, (ii) sound modulation as a guide to pattern comprehension in speech, animal vocalization and music, (iii) social strategies for mutual understanding, survival and group cohesion. We conclude emphasizing the interplay between these three sets of cognitive processes as a fundamental dimension grounding the emergence of the human ability for propositional language.
  • Filippi, P. (2013). Specifically Human: Going Beyond Perceptual Syntax. Biosemiotics, 7(1), 111-123. doi:10.1007/s12304-013-9187-3.

    Abstract

    The aim of this paper is to help refine the definition of humans as “linguistic animals” in light of a comparative approach on nonhuman animals’ cognitive systems. As Uexküll & Kriszat (1934/1992) have theorized, the epistemic access to each species-specific environment (Umwelt) is driven by different biocognitive processes. Within this conceptual framework, I identify the salient cognitive process that distinguishes each species typical perception of the world as the faculty of language meant in the following operational definition: the ability to connect different elements according to structural rules. In order to draw some conclusions about humans’ specific faculty of language, I review different empirical studies on nonhuman animals’ ability to recognize formal patterns of tokens. I suggest that what differentiates human language from other animals’ cognitive systems is the ability to categorize the units of a pattern, going beyond its perceptual aspects. In fact, humans are the only species known to be able to combine semantic units within a network of combinatorial logical relationships (Deacon 1997) that can be linked to the state of affairs in the external world (Wittgenstein 1922). I assume that this ability is the core cognitive process underlying a) the capacity to speak (or to reason) in verbal propositions and b) the general human faculty of language expressed, for instance, in the ability to draw visual conceptual maps or to compute mathematical expressions. In light of these considerations, I conclude providing some research questions that could lead to a more detailed comparative exploration of the faculty of language.
  • Fisher, S. E. (2013). Building bridges between genes, brains and language. In J. J. Bolhuis, & M. Everaert (Eds.), Birdsong, speech and language: Exploring the evolution of mind and brain (pp. 425-454). Cambridge, Mass: MIT Press.
  • Fisher, S. E., Hatchwell, E., Chand, A., Ockenden, N., Monaco, A. P., & Craig, I. W. (1995). Construction of two YAC contigs in human Xp11.23-p11.22, one encompassing the loci OATL1, GATA, TFE3, and SYP, the other linking DXS255 to DXS146. Genomics, 29(2), 496-502. doi:10.1006/geno.1995.9976.

    Abstract

    We have constructed two YAC contigs in the Xp11.23-p11.22 interval of the human X chromosome, a region that was previously poorly characterized. One contig, of at least 1.4 Mb, links the pseudogene OATL1 to the genes GATA1, TFE3, and SYP and also contains loci implicated in Wiskott-Aldrich syndrome and synovial sarcoma. A second contig, mapping proximal to the first, is estimated to be over 2.1 Mb and links the hypervariable locus DXS255 to DXS146, and also contains a chloride channel gene that is responsible for hereditary nephrolithiasis. We have used plasmid rescue, inverse PCR, and Alu-PCR to generate 20 novel markers from this region, 1 of which is polymorphic, and have positioned these relative to one another on the basis of YAC analysis. The order of previously known markers within our contigs, Xpter-OATL1-GATA-TFE3-SYP-DXS255146- Xcen, agrees with genomic pulsed-field maps of the region. In addition, we have constructed a rare-cutter restriction map for a 710-kb region of the DXS255-DXS146 contig and have identified three CPG islands. These contigs and new markers will provide a useful resource for more detailed analysis of Xp11.23-p11.22, a region implicated in several genetic diseases.
  • Fisher, S. E., & Ridley, M. (2013). Culture, genes, and the human revolution. Science, 340(6135), 929-930. doi:10.1126/science.1236171.

    Abstract

    State-of-the-art DNA sequencing is providing ever more detailed insights into the genomes of humans, extant apes, and even extinct hominins (1–3), offering unprecedented opportunities to uncover the molecular variants that make us human. A common assumption is that the emergence of behaviorally modern humans after 200,000 years ago required—and followed—a specific biological change triggered by one or more genetic mutations. For example, Klein has argued that the dawn of human culture stemmed from a single genetic change that “fostered the uniquely modern ability to adapt to a remarkable range of natural and social circumstance” (4). But are evolutionary changes in our genome a cause or a consequence of cultural innovation (see the figure)?

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  • Fisher, S. E., Van Bakel, I., Lloyd, S. E., Pearce, S. H. S., Thakker, R. V., & Craig, I. W. (1995). Cloning and characterization of CLCN5, the human kidney chloride channel gene implicated in Dent disease (an X-linked hereditary nephrolithiasis). Genomics, 29, 598-606. doi:10.1006/geno.1995.9960.

    Abstract

    Dent disease, an X-linked familial renal tubular disorder, is a form of Fanconi syndrome associated with proteinuria, hypercalciuria, nephrocalcinosis, kidney stones, and eventual renal failure. We have previously used positional cloning to identify the 3' part of a novel kidney-specific gene (initially termed hClC-K2, but now referred to as CLCN5), which is deleted in patients from one pedigree segregating Dent disease. Mutations that disrupt this gene have been identified in other patients with this disorder. Here we describe the isolation and characterization of the complete open reading frame of the human CLCN5 gene, which is predicted to encode a protein of 746 amino acids, with significant homology to all known members of the ClC family of voltage-gated chloride channels. CLCN5 belongs to a distinct branch of this family, which also includes the recently identified genes CLCN3 and CLCN4. We have shown that the coding region of CLCN5 is organized into 12 exons, spanning 25-30 kb of genomic DNA, and have determined the sequence of each exon-intron boundary. The elucidation of the coding sequence and exon-intron organization of CLCN5 will both expedite the evaluation of structure/function relationships of these ion channels and facilitate the screening of other patients with renal tubular dysfunction for mutations at this locus.
  • Fisher, S. E. (2007). Molecular windows into speech and language disorders. Folia Phoniatrica et Logopaedica, 59, 130-140. doi:10.1159/000101771.

    Abstract

    Why do some children fail to acquire speech and language skills despite adequate environmental input and overtly normal neurological and anatomical development? It has been suspected for several decades, based on indirect evidence, that the human genome might hold some answers to this enigma. These suspicions have recently received dramatic confirmation with the discovery of specific genetic changes which appear sufficient to derail speech and language development. Indeed, researchers are already using information from genetic studies to aid early diagnosis and to shed light on the neural pathways that are perturbed in these inherited forms of speech and language disorder. Thus, we have entered an exciting era for dissecting the neural bases of human communication, one which takes genes and molecules as a starting point. In the current article I explain how this recent paradigm shift has occurred and describe the new vistas that have opened up. I demonstrate ways of bridging the gaps between molecules, neurons and the brain, which will provide a new understanding of the aetiology of speech and language impairments.
  • Fisher, S. E., Black, G. C. M., Lloyd, S. E., Wrong, O. M., Thakker, R. V., & Craig, I. W. (1994). Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dent's disease (an X-linked hereditary nephrolithiasis). Human Molecular Genetics, 3, 2053-2059.

    Abstract

    Dent's disease, an X-linked renal tubular disorder, is a form of Fanconi syndrome which is characterized by proteinuria, hypercalciuria, nephrocalcinosis, kidney stones and renal failure. Previous studies localised the gene responsible to Xp11.22, within a microdeletion involving the hypervariable locus DXS255. Further analysis using new probes which flank this locus indicate that the deletion is less than 515 kb. A 185 kb YAC containing DXS255 was used to screen a cDNA library from adult kidney in order to isolate coding sequences falling within the deleted region which may be implicated in the disease aetiology. We identified two clones which are evolutionarily conserved, and detect a 9.5 kb transcript which is expressed predominantly in the kidney. Sequence analysis of 780 bp of ORF from the clones suggests that the identified gene, termed hCIC-K2, encodes a new member of the CIC family of voltage-gated chloride channels. Genomic fragments detected by the cDNA clones are completely absent in patients who have an associated microdeletion. On the basis of the expression pattern, proposed function and deletion mapping, hCIC-K2 is a strong candidate for Dent's disease.
  • Fitch, W. T., Friederici, A. D., & Hagoort, P. (Eds.). (2012). Pattern perception and computational complexity [Special Issue]. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 367 (1598).
  • Fitch, W. T., Friederici, A. D., & Hagoort, P. (2012). Pattern perception and computational complexity: Introduction to the special issue. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 367 (1598), 1925-1932. doi:10.1098/rstb.2012.0099.

    Abstract

    Research on pattern perception and rule learning, grounded in formal language theory (FLT) and using artificial grammar learning paradigms, has exploded in the last decade. This approach marries empirical research conducted by neuroscientists, psychologists and ethologists with the theory of computation and FLT, developed by mathematicians, linguists and computer scientists over the last century. Of particular current interest are comparative extensions of this work to non-human animals, and neuroscientific investigations using brain imaging techniques. We provide a short introduction to the history of these fields, and to some of the dominant hypotheses, to help contextualize these ongoing research programmes, and finally briefly introduce the papers in the current issue.
  • Fitneva, S. A., Lam, N. H. L., & Dunfield, K. A. (2013). The development of children's information gathering: To look or to ask? Developmental Psychology, 49(3), 533-542. doi:10.1037/a0031326.

    Abstract

    The testimony of others and direct experience play a major role in the development of children's knowledge. Children actively use questions to seek others' testimony and explore the environment. It is unclear though whether children distinguish when it is better to ask from when it is better to try to find an answer by oneself. In 2 experiments, we examined the ability of 4- and 6-year-olds to select between looking and asking to determine visible and invisible properties of entities (e.g., hair color vs. knowledge of French). All children chose to look more often for visible than invisible properties. However, only 6-year-olds chose above chance to look for visible properties and to ask for invisible properties. Four-year-olds showed a preference for looking in one experiment and asking in the other. The results suggest substantial development in the efficacy of children's learning in early childhood.
  • FitzPatrick, I. (2007). Effects of sentence context in L2 natural speech comprehension. Nijmegen CNS, 2, 43-56.

    Abstract

    Electrophysiological studies consistently find N400 effects of semantic incongruity in non-native written language comprehension. Typically these N400 effects are later than N400 effects in native comprehension, suggesting that semantic processing in one’s second language (L2) may be delayed compared to one’s first language (L1). In this study we were firstly interested in replicating the semantic incongruity effect using natural auditory speech, which poses strong demands on the speed of processing. Secondly, we wished to investigate whether a possible delay in semantic processing might be due to bilinguals accessing lexical items from both their L1 and L2 (a more extensive lexical search). We recorded EEG from 30 Dutch-English bilinguals who listened to English sentences � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � � ��� � � in which the sentence-final word was: (1) semantically fitting, (2) semantically incongruent, (3) initially congruent: semantically incongruent, but sharing initial phonemes with the most probable sentence completion within the L2, (4) semantically incongruent, but sharing initial phonemes with the L1 translation equivalent of the most probable sentence completion. We found an N400 effect in each of the semantically incongruent conditions. This N400 effect was significantly delayed to L2 words that were initially congruent with the sentence context. We found no effect of initial overlap with L1 translation equivalents. Taken together these findings firstly demonstrate that non-native listeners are sensitive to semantic incongruity in natural speech, secondly indicate that semantic integration in non-native listening can start on the basis of word initial phonemes, and finally suggest that during L2 sentence processing listeners do not access the L1 lexicon.
  • Flecken, M., & Gerwien, J. (2013). Grammatical aspect modulates event duration estimations: findings from Dutch. In M. Knauff, M. Pauen, N. Sebanz, & I. Wachsmuth (Eds.), Proceedings of the 35th annual meeting of the Cognitive Science Society (CogSci 2013) (pp. 2309-2314). Austin,TX: Cognitive Science Society.
  • Flecken, M., von Stutterheim, C., & Carroll, M. (2013). Principles of information organization in L2 use: Complex patterns of conceptual transfer. International review of applied linguistics, 51(2), 229-242. doi:10.1515/iral-2013-0010.
  • Flecken, M., & Schmiedtova, B. (2007). The expression of simultaneity in L1 Dutch. Toegepaste Taalwetenschap in Artikelen, 77(1), 67-78.
  • Floyd, S. (2012). Book review of [Poeticas de vida en espacios de muerte: Ge´ nero, poder y estado en la contidianeidad warao [Poetics of life in spaces of death: Gender, power and the state in Warao everyday life] Charles L. Briggs. Quito, Ecuador: Abya Yala, 2008. 460 pp.]. American Anthropologist, 114, 543 -544. doi:10.1111/j.1548-1433.2012.01461_1.x.

    Abstract

    No abstract is available for this article
  • Floyd, S. (2007). Changing times and local terms on the Rio Negro, Brazil: Amazonian ways of depolarizing epistemology, chronology and cultural Change. Latin American and Caribbean Ethnic studies, 2(2), 111-140. doi:10.1080/17442220701489548.

    Abstract

    Partway along the vast waterways of Brazil's middle Rio Negro, upstream from urban Manaus and downstream from the ethnographically famous Northwest Amazon region, is the town of Castanheiro, whose inhabitants skillfully negotiate a space between the polar extremes of 'traditional' and 'acculturated.' This paper takes an ethnographic look at the non-polarizing terms that these rural Amazonian people use for talking about cultural change. While popular and academic discourses alike have often framed cultural change in the Amazon as a linear process, Amazonian discourse provides resources for describing change as situated in shifting fields of knowledge of the social and physical environments, better capturing its non-linear complexity and ambiguity.
  • Floyd, S. (2013). [Review of the book Lessons from a Quechua strongwoman: ideophony, dialogue and perspective. by Janis Nuckolls. 2010]. Journal of Linguistic Anthropology, 22, 256-258. doi:10.1111/j.1548-1395.2012.01166.x.
  • Floyd, S. (2013). Semantic transparency and cultural calquing in the Northwest Amazon. In P. Epps, & K. Stenzel (Eds.), Upper Rio Negro: Cultural and linguistic interaction in northwestern Amazonia (pp. 271-308). Rio de Janiero: Museu do Indio. Retrieved from http://www.museunacional.ufrj.br/ppgas/livros_ele.html.

    Abstract

    The ethnographic literature has sometimes described parts of the northwest Amazon as areas of shared culture across linguistic groups. This paper illustrates how a principle of semantic transparency across languages is a key means of establishing elements of a common regional culture through practices like the calquing of ethnonyms and toponyms so that they are semantically, but not phonologically, equivalent across languages. It places the upper Rio Negro area of the northwest Amazon in a general discussion of cross-linguistic naming practices in South America and considers the extent to which a preference for semantic transparency can be linked to cases of widespread cultural ‘calquing’, in which culturally-important meanings are kept similar across different linguistic systems. It also addresses the principle of semantic transparency beyond specific referential phrases and into larger discourse structures. It concludes that an attention to semiotic practices in multilingual settings can provide new and more complex ways of thinking about the idea of shared culture.
  • Fonteijn, H. M., Modat, M., Clarkson, M. J., Barnes, J., Lehmann, M., Hobbs, N. Z., Scahill, R. I., Tabrizi, S. J., Ourselin, S., Fox, N. C., & Alexander, D. C. (2012). An event-based model for disease progression and its application in familial Alzheimer's disease and Huntington's disease. NeuroImage, 60, 1880-1889. doi:10.1016/j.neuroimage.2012.01.062.

    Abstract

    Understanding the progression of neurological diseases is vital for accurate and early diagnosis and treatment planning. We introduce a new characterization of disease progression, which describes the disease as a series of events, each comprising a significant change in patient state. We provide novel algorithms to learn the event ordering from heterogeneous measurements over a whole patient cohort and demonstrate using combined imaging and clinical data from familial-Alzheimer's and Huntington's disease cohorts. Results provide new detail in the progression pattern of these diseases, while confirming known features, and give unique insight into the variability of progression over the cohort. The key advantage of the new model and algorithms over previous progression models is that they do not require a priori division of the patients into clinical stages. The model and its formulation extend naturally to a wide range of other diseases and developmental processes and accommodate cross-sectional and longitudinal input data.
  • Franceschini, R. (2012). Wolfgang Klein und die LiLi [Laudatio]. Zeitschrift für Literaturwissenschaft und Linguistik, 42(168), 5-7.
  • Francks, C., Maegawa, S., Laurén, J., Abrahams, B. S., Velayos-Baeza, A., Medland, S. E., Colella, S., Groszer, M., McAuley, E. Z., Caffrey, T. M., Timmusk, T., Pruunsild, P., Koppel, I., Lind, P. A., Matsumoto-Itaba, N., Nicod, J., Xiong, L., Joober, R., Enard, W., Krinsky, B. and 22 moreFrancks, C., Maegawa, S., Laurén, J., Abrahams, B. S., Velayos-Baeza, A., Medland, S. E., Colella, S., Groszer, M., McAuley, E. Z., Caffrey, T. M., Timmusk, T., Pruunsild, P., Koppel, I., Lind, P. A., Matsumoto-Itaba, N., Nicod, J., Xiong, L., Joober, R., Enard, W., Krinsky, B., Nanba, E., Richardson, A. J., Riley, B. P., Martin, N. G., Strittmatter, S. M., Möller, H.-J., Rujescu, D., St Clair, D., Muglia, P., Roos, J. L., Fisher, S. E., Wade-Martins, R., Rouleau, G. A., Stein, J. F., Karayiorgou, M., Geschwind, D. H., Ragoussis, J., Kendler, K. S., Airaksinen, M. S., Oshimura, M., DeLisi, L. E., & Monaco, A. P. (2007). LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Molecular Psychiatry, 12, 1129-1139. doi:10.1038/sj.mp.4002053.

    Abstract

    Left-right asymmetrical brain function underlies much of human cognition, behavior and emotion. Abnormalities of cerebral asymmetry are associated with schizophrenia and other neuropsychiatric disorders. The molecular, developmental and evolutionary origins of human brain asymmetry are unknown. We found significant association of a haplotype upstream of the gene LRRTM1 (Leucine-rich repeat transmembrane neuronal 1) with a quantitative measure of human handedness in a set of dyslexic siblings, when the haplotype was inherited paternally (P=0.00002). While we were unable to find this effect in an epidemiological set of twin-based sibships, we did find that the same haplotype is overtransmitted paternally to individuals with schizophrenia/schizoaffective disorder in a study of 1002 affected families (P=0.0014). We then found direct confirmatory evidence that LRRTM1 is an imprinted gene in humans that shows a variable pattern of maternal downregulation. We also showed that LRRTM1 is expressed during the development of specific forebrain structures, and thus could influence neuronal differentiation and connectivity. This is the first potential genetic influence on human handedness to be identified, and the first putative genetic effect on variability in human brain asymmetry. LRRTM1 is a candidate gene for involvement in several common neurodevelopmental disorders, and may have played a role in human cognitive and behavioral evolution.
  • Frank, S. L., Koppen, M., Noordman, L. G. M., & Vonk, W. (2007). Coherence-driven resolution of referential ambiguity: A computational model. Memory & Cognition, 35(6), 1307-1322.

    Abstract

    We present a computational model that provides a unified account of inference, coherence, and disambiguation. It simulates how the build-up of coherence in text leads to the knowledge-based resolution of referential ambiguity. Possible interpretations of an ambiguity are represented by centers of gravity in a high-dimensional space. The unresolved ambiguity forms a vector in the same space. This vector is attracted by the centers of gravity, while also being affected by context information and world knowledge. When the vector reaches one of the centers of gravity, the ambiguity is resolved to the corresponding interpretation. The model accounts for reading time and error rate data from experiments on ambiguous pronoun resolution and explains the effects of context informativeness, anaphor type, and processing depth. It shows how implicit causality can have an early effect during reading. A novel prediction is that ambiguities can remain unresolved if there is insufficient disambiguating information.
  • Frank, S. L., Koppen, M., Noordman, L. G. M., & Vonk, W. (2007). Modeling multiple levels of text presentation. In F. Schmalhofer, & C. A. Perfetti (Eds.), Higher level language processes in the brain: Inference and comprehension processes (pp. 133-157). Mahwah, NJ: Erlbaum.
  • Franken, M. K., Huizinga, C. S. M., & Schiller, N. O. (2012). De grafemische buffer: Aspecten van een spellingstoornis. Stem- Spraak- en Taalpathologie, 17(3), 17-36.

    Abstract

    A spelling disorder that received much attention recently is the so-called graphemic buffer impairment. Caramazza et al. (1987) presented the first systematic case study of a patient with this disorder. Miceli & Capasso (2006) provide an extensive overview of the relevant literature. This article adds to the literature by describing a Dutch case, i.e. patient BM. We demonstrate how specific features of Dutch and Dutch orthography interact with the graphemic buffer impairment. In addition, we paid special attention to the influence of grapheme position on the patient’s spelling accuracy. For this we used, in contrast with most of the previous literature, the proportional accountability method described in Machtynger & Shallice (2009). We show that by using this method the underlying error distribution can be more optimally captured than with classical methods. The result of this analysis replicates two distributions that have been previously reported in the literature. Finally, attention will be paid to the role of phonology in the described disorder.
  • French, C. A., Jin, X., Campbell, T. G., Gerfen, E., Groszer, M., Fisher, S. E., & Costa, R. M. (2012). An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning. Molecular Psychiatry, 17, 1077-1085. doi:10.1038/mp.2011.105.

    Abstract

    Mutations in the human FOXP2 gene cause impaired speech development and linguistic deficits, which have been best characterised in a large pedigree called the KE family. The encoded protein is highly conserved in many vertebrates and is expressed in homologous brain regions required for sensorimotor integration and motor-skill learning, in particular corticostriatal circuits. Independent studies in multiple species suggest that the striatum is a key site of FOXP2 action. Here, we used in vivo recordings in awake-behaving mice to investigate the effects of the KE-family mutation on the function of striatal circuits during motor-skill learning. We uncovered abnormally high ongoing striatal activity in mice carrying an identical mutation to that of the KE family. Furthermore, there were dramatic alterations in striatal plasticity during the acquisition of a motor skill, with most neurons in mutants showing negative modulation of firing rate, starkly contrasting with the predominantly positive modulation seen in control animals. We also observed striking changes in the temporal coordination of striatal firing during motor-skill learning in mutants. Our results indicate that FOXP2 is critical for the function of striatal circuits in vivo, which are important not only for speech but also for other striatal-dependent skills.

    Additional information

    French_2011_Supplementary_Info.pdf
  • French, C. A., Groszer, M., Preece, C., Coupe, A.-M., Rajewsky, K., & Fisher, S. E. (2007). Generation of mice with a conditional Foxp2 null allele. Genesis, 45(7), 440-446. doi:10.1002/dvg.20305.

    Abstract

    Disruptions of the human FOXP2 gene cause problems with articulation of complex speech sounds, accompanied by impairment in many aspects of language ability. The FOXP2/Foxp2 transcription factor is highly similar in humans and mice, and shows a complex conserved expression pattern, with high levels in neuronal subpopulations of the cortex, striatum, thalamus, and cerebellum. In the present study we generated mice in which loxP sites flank exons 12-14 of Foxp2; these exons encode the DNA-binding motif, a key functional domain. We demonstrate that early global Cre-mediated recombination yields a null allele, as shown by loss of the loxP-flanked exons at the RNA level and an absence of Foxp2 protein. Homozygous null mice display severe motor impairment, cerebellar abnormalities and early postnatal lethality, consistent with other Foxp2 mutants. When crossed to transgenic lines expressing Cre protein in a spatially and/or temporally controlled manner, these conditional mice will provide new insights into the contributions of Foxp2 to distinct neural circuits, and allow dissection of roles during development and in the mature brain.
  • Frost, R. L. A., Gaskell, G., Warker, J., Guest, J., Snowdon, R., & Stackhouse, A. (2012). Sleep Facilitates Acquisition of Implicit Phonotactic Constraints in Speech Production. Journal of sleep research, 21(s1), 249-249. doi:10.1111/j.1365-2869.2012.01044.x.

    Abstract

    Sleep plays an important role in neural reorganisation which underpins memory consolidation. The gradual replacement of
    hippocampal binding of new memories with intracortical connections helps to link new memories to existing knowledge. This process appears to be faster for memories which fit more easily into existing schemas. Here we seek to investigate whether this more rapid consolidation of schema-conformant information is facilitated by
    sleep, and the neural basis of this process.
  • Fueller, C., Loescher, J., & Indefrey, P. (2013). Writing superiority in cued recall. Frontiers in Psychology, 4: 764. doi:10.3389/fpsyg.2013.00764.

    Abstract

    In list learning paradigms with free recall, written recall has been found to be less susceptible to intrusions of related concepts than spoken recall when the list items had been visually presented. This effect has been ascribed to the use of stored orthographic representations from the study phase during written recall (Kellogg, 2001). In other memory retrieval paradigms, by contrast, either better recall for modality-congruent items or an input-independent writing superiority effect have been found (Grabowski, 2005). In a series of four experiments using a paired associate learning paradigm we tested (a) whether output modality effects on verbal recall can be replicated in a paradigm that does not involve the rejection of semantically related intrusion words, (b) whether a possible superior performance for written recall was due to a slower response onset for writing as compared to speaking in immediate recall, and (c) whether the performance in paired associate word recall was correlated with performance in an additional episodic memory recall task. We observed better written recall in the first half of the recall phase, irrespective of the modality in which the material was presented upon encoding. An explanation for this effect based on longer response latencies for writing and hence more time for memory retrieval could be ruled out by showing that the effect persisted in delayed response versions of the task. Although there was some evidence that stored additional episodic information may contribute to the successful retrieval of associate words, this evidence was only found in the immediate response experiments and hence is most likely independent from the observed output modality effect. In sum, our results from a paired associate learning paradigm suggest that superior performance for written vs. spoken recall cannot be (solely) explained in terms of additional access to stored orthographic representations from the encoding phase. Our findings rather suggest a general writing-superiority effect at the time of memory retrieval.
  • De la Fuente, J., Santiago, J., Roma, A., Dumitrache, C., & Casasanto, D. (2012). Facing the past: cognitive flexibility in the front-back mapping of time [Abstract]. Cognitive Processing; Special Issue "ICSC 2012, the 5th International Conference on Spatial Cognition: Space and Embodied Cognition". Poster Presentations, 13(Suppl. 1), S58.

    Abstract

    In many languages the future is in front and the past behind, but in some cultures (like Aymara) the past is in front. Is it possible to find this mapping as an alternative conceptualization of time in other cultures? If so, what are the factors that affect its choice out of the set of available alternatives? In a paper and pencil task, participants placed future or past events either in front or behind a character (a schematic head viewed from above). A sample of 24 Islamic participants (whose language also places the future in front and the past behind) tended to locate the past event in the front box more often than Spanish participants. This result might be due to the greater cultural value assigned to tradition in Islamic culture. The same pattern was found in a sample of Spanish elders (N = 58), what may support that conclusion. Alternatively, the crucial factor may be the amount of attention paid to the past. In a final study, young Spanish adults (N = 200) who had just answered a set of questions about their past showed the past-in-front pattern, whereas questions about their future exacerbated the future-in-front pattern. Thus, the attentional explanation was supported: attended events are mapped to front space in agreement with the experiential connection between attending and seeing. When attention is paid to the past, it tends to occupy the front location in spite of available alternative mappings in the language-culture.
  • Furman, R. (2012). Caused motion events in Turkish: Verbal and gestural representation in adults and children. PhD Thesis, Radboud University Nijmegen/LOT.

    Abstract

    Caused motion events (e.g. a boy pulls a box into a room) are basic events where an Agent (the boy) performs an Action (pulling) that causes a Figure (box) to move in a spatial Path (into) to a Goal (the room). These semantic elements are mapped onto lexical and syntactic structures differently across languages This dissertation investigates the encoding of caused motion events in Turkish, and the development of this encoding in speech and gesture. First, a linguistic analysis shows that Turkish does not fully fit into the expected typological patterns, and that the encoding of caused motion is determined by the fine-grained lexical semantics of a verb as well as the syntactic construction the verb is integrated into. A grammaticality judgment study conducted with adult Turkish speakers further establishes the fundamentals of the encoding patterns. An event description study compares adults’ verbal and gestural representations of caused motion to those of children aged 3 to 5. The findings indicate that although language-specificity is evident in children’s speech and gestures, the development of adult patterns takes time and occurs after the age of 5. A final study investigates a longitudinal video corpus of the spontaneous speech of Turkish-speaking children aged 1 to 3, and finds that language-specificity is evident from the start in both children’s speech and gesture. Apart from contributing to the literature on the development of Turkish, this dissertation furthers our understanding of the interaction between language-specificity and the multimodal expression of semantic information in event descriptions.
  • Furman, R., & Ozyurek, A. (2007). Development of interactional discourse markers: Insights from Turkish children's and adults' narratives. Journal of Pragmatics, 39(10), 1742-1757. doi:10.1016/j.pragma.2007.01.008.

    Abstract

    Discourse markers (DMs) are linguistic elements that index different relations and coherence between units of talk (Schiffrin, Deborah, 1987. Discourse Markers. Cambridge University Press, Cambridge). Most research on the development of these forms has focused on conversations rather than narratives and furthermore has not directly compared children's use of DMs to adult usage. This study examines the development of three DMs (şey ‘uuhh’, yani ‘I mean’, işte ‘y’know’) that mark interactional levels of discourse in oral Turkish narratives in 60 Turkish children (3-, 5- and 9-year-olds) and 20 Turkish-speaking adults. The results show that the frequency and functions of DMs change with age. Children learn şey, which mainly marks exchange level structures, earliest. However, yani and işte have multi-functions such as marking both information states and participation frameworks and are consequently learned later. Children also use DMs with different functions than adults. Overall, the results show that learning to use interactional DMs in narratives is complex and goes beyond age 9, especially for multi-functional DMs that index an interplay of discourse coherence at different levels.
  • Furuyama, N., & Sekine, K. (2007). Forgetful or strategic? The mystery of the systematic avoidance of reference in the cartoon story nsarrative. In S. D. Duncan, J. Cassel, & E. T. Levy (Eds.), Gesture and the Dynamic Dimension of Language: Essays in honor of David McNeill (pp. 75-81). Amsterdam: John Benjamins Publishing Company.
  • Gaby, A. (2012). The Thaayorre lexicon of putting and taking. In A. Kopecka, & B. Narasimhan (Eds.), Events of putting and taking: A crosslinguistic perspective (pp. 233-252). Amsterdam: Benjamins.

    Abstract

    This paper investigates the lexical semantics and relative distributions of verbs describing putting and taking events in Kuuk Thaayorre, a Pama-Nyungan language of Cape York (Australia). Thaayorre put/take verbs can be subcategorised according to whether they may combine with an NP encoding a goal, an NP encoding a source, or both. Goal NPs are far more frequent in natural discourse: initial analysis shows 85% of goal-oriented verb tokens to be accompanied by a goal NP, while only 31% of source-oriented verb tokens were accompanied by a source. This finding adds weight to Ikegami’s (1987) assertion of the conceptual primacy of goals over sources, reflected in a cross-linguistic dissymmetry whereby goal-marking is less marked and more widely used than source-marking.
  • Ganushchak, L. Y., Krott, A., & Meyer, A. S. (2012). From gr8 to great: Lexical access to SMS shortcuts. Frontiers in Psychology, 3, 150. doi:10.3389/fpsyg.2012.00150.

    Abstract

    Many contemporary texts include shortcuts, such as cu or phones4u. The aim of this study was to investigate how the meanings of shortcuts are retrieved. A primed lexical decision paradigm was used with shortcuts and the corresponding words as primes. The target word was associatively related to the meaning of the whole prime (cu/see you – goodbye), to a component of the prime (cu/see you – look), or unrelated to the prime. In Experiment 1, primes were presented for 57 ms. For both word and shortcut primes, responses were faster to targets preceded by whole-related than by unrelated primes. No priming from component-related primes was found. In Experiment 2, the prime duration was 1000 ms. The priming effect seen in Experiment 1 was replicated. Additionally, there was priming from component-related word primes, but not from component-related shortcut primes. These results indicate that the meanings of shortcuts can be retrieved without translating them first into corresponding words.
  • Ganushchak, L. Y., Krott, A., Frisson, S., & Meyer, A. S. (2013). Processing words and Short Message Service shortcuts in sentential contexts: An eye movement study. Applied Psycholinguistics, 34, 163-179. doi:10.1017/S0142716411000658.

    Abstract

    The present study investigated whether Short Message Service shortcuts are more difficult to process in sentence context than the spelled-out word equivalent and, if so, how any additional processing difficulty arises. Twenty-four student participants read 37 Short Message Service shortcuts and word equivalents embedded in semantically plausible and implausible contexts (e.g., He left/drank u/you a note) while their eye movements were recorded. There were effects of plausibility and spelling on early measures of processing difficulty (first fixation durations, gaze durations, skipping, and first-pass regression rates for the targets), but there were no interactions of plausibility and spelling. Late measures of processing difficulty (second run gaze duration and total fixation duration) were only affected by plausibility but not by spelling. These results suggest that shortcuts are harder to recognize, but that, once recognized, they are integrated into the sentence context as easily as ordinary words.
  • Gao, X., Levinthal, B. R., & Stine-Morrow, E. A. L. (2012). The effects of ageing and visual noise on conceptual integration during sentence reading. Quarterly journal of experimental psychology, 65(9), 1833-1847. doi:10.1080/17470218.2012.674146.

    Abstract

    The effortfulness hypothesis implies that difficulty in decoding the surface form, as in the case of age-related sensory limitations or background noise, consumes the attentional resources that are then unavailable for semantic integration in language comprehension. Because ageing is associated with sensory declines, degrading of the surface form by a noisy background can pose an extra challenge for older adults. In two experiments, this hypothesis was tested in a self-paced moving window paradigm in which younger and older readers' online allocation of attentional resources to surface decoding and semantic integration was measured as they read sentences embedded in varying levels of visual noise. When visual noise was moderate (Experiment 1), resource allocation among young adults was unaffected but older adults allocated more resources to decode the surface form at the cost of resources that would otherwise be available for semantic processing; when visual noise was relatively intense (Experiment 2), both younger and older participants allocated more attention to the surface form and less attention to semantic processing. The decrease in attentional allocation to semantic integration resulted in reduced recall of core ideas in both experiments, suggesting that a less organized semantic representation was constructed in noise. The greater vulnerability of older adults at relatively low levels of noise is consistent with the effortfulness hypothesis.
  • Gauvin, H. S., Hartsuiker, R. J., & Huettig, F. (2013). Speech monitoring and phonologically-mediated eye gaze in language perception and production: A comparison using printed word eye-tracking. Frontiers in Human Neuroscience, 7: 818. doi:10.3389/fnhum.2013.00818.

    Abstract

    The Perceptual Loop Theory of speech monitoring assumes that speakers routinely inspect their inner speech. In contrast, Huettig and Hartsuiker (2010) observed that listening to one’s own speech during language production drives eye-movements to phonologically related printed words with a similar time-course as listening to someone else’s speech does in speech perception experiments. This suggests that speakers listen to their own overt speech, but not to their inner speech. However, a direct comparison between production and perception with the same stimuli and participants is lacking so far. The current printed word eye-tracking experiment therefore used a within-subjects design, combining production and perception. Displays showed four words, of which one, the target, either had to be named or was presented auditorily. Accompanying words were phonologically related, semantically related, or unrelated to the target. There were small increases in looks to phonological competitors with a similar time-course in both production and perception. Phonological effects in perception however lasted longer and had a much larger magnitude. We conjecture that this difference is related to a difference in predictability of one’s own and someone else’s speech, which in turn has consequences for lexical competition in other-perception and possibly suppression of activation in self-perception.
  • Gavin, M., Botero, C. A., Bowern, C., Colwell, R. K., Dunn, M., Dunn, R. R., Gray, R. D., Kirby, K. R., McCarter, J., Powell, A., Rangel, T. F., Steppe, J. R., Trautwein, M., Verdolin, J. L., & Yanega, G. (2013). Towards a mechanistic understanding of linguistic diversity. Bioscience, 63, 524-535. doi:10.1525/bio.2013.63.7.6.

    Abstract

    Our species displays remarkable linguistic diversity. While the uneven distribution of this diversity demands explanation, the drivers of these patterns have not been conclusively determined. We address this issue in two steps. First, we review previous empirical studies that have suggested environmental, geographical, and socio-cultural drivers of linguistic diversification. However, contradictory results and methodological variation make it difficult to draw general conclusions. Second, we outline a program for future research. We suggest that future analyses should account for interactions among causal factors, lack of spatial and phylogenetic independence of data, and transitory patterns. Recent analytical advances in biogeography and evolutionary biology, such as simulation modeling of diversity patterns, hold promise for testing four key mechanisms of language diversification proposed here: neutral change, population movement, contact, and selection. Future modeling approaches should also evaluate how the outcomes of these processes are influenced by demography, environmental heterogeneity, and time.
  • Gebre, B. G., Wittenburg, P., & Heskes, T. (2013). Automatic sign language identification. In Proceeding of the 20th IEEE International Conference on Image Processing (ICIP) (pp. 2626-2630).

    Abstract

    We propose a Random-Forest based sign language identification system. The system uses low-level visual features and is based on the hypothesis that sign languages have varying distributions of phonemes (hand-shapes, locations and movements). We evaluated the system on two sign languages -- British SL and Greek SL, both taken from a publicly available corpus, called Dicta Sign Corpus. Achieved average F1 scores are about 95% - indicating that sign languages can be identified with high accuracy using only low-level visual features.
  • Gebre, B. G., Wittenburg, P., & Heskes, T. (2013). Automatic signer diarization - the mover is the signer approach. In Computer Vision and Pattern Recognition Workshops (CVPRW), 2013 IEEE Conference on (pp. 283-287). doi:10.1109/CVPRW.2013.49.

    Abstract

    We present a vision-based method for signer diarization -- the task of automatically determining "who signed when?" in a video. This task has similar motivations and applications as speaker diarization but has received little attention in the literature. In this paper, we motivate the problem and propose a method for solving it. The method is based on the hypothesis that signers make more movements than their interlocutors. Experiments on four videos (a total of 1.4 hours and each consisting of two signers) show the applicability of the method. The best diarization error rate (DER) obtained is 0.16.
  • Gebre, B. G., & Wittenburg, P. (2012). Adaptive automatic gesture stroke detection. In J. C. Meister (Ed.), Digital Humanities 2012 Conference Abstracts. University of Hamburg, Germany; July 16–22, 2012 (pp. 458-461).

    Abstract

    Print Friendly XML Gebre, Binyam Gebrekidan, Max Planck Institute for Psycholinguistics, The Netherlands, binyamgebrekidan.gebre [at] mpi.nl Wittenburg, Peter, Max Planck Institute for Psycholinguistics, The Netherlands, peter.wittenburg [at] mpi.nl Introduction Many gesture and sign language researchers manually annotate video recordings to systematically categorize, analyze and explain their observations. The number and kinds of annotations are so diverse and unpredictable that any attempt at developing non-adaptive automatic annotation systems is usually less effective. The trend in the literature has been to develop models that work for average users and for average scenarios. This approach has three main disadvantages. First, it is impossible to know beforehand all the patterns that could be of interest to all researchers. Second, it is practically impossible to find enough training examples for all patterns. Third, it is currently impossible to learn a model that is robustly applicable across all video quality-recording variations.
  • Gebre, B. G., Zampieri, M., Wittenburg, P., & Heskes, T. (2013). Improving Native Language Identification with TF-IDF weighting. In Proceedings of the Eighth Workshop on Innovative Use of NLP for Building Educational Applications (pp. 216-223).

    Abstract

    This paper presents a Native Language Identification (NLI) system based on TF-IDF weighting schemes and using linear classifiers - support vector machines, logistic regressions and perceptrons. The system was one of the participants of the 2013 NLI Shared Task in the closed-training track, achieving 0.814 overall accuracy for a set of 11 native languages. This accuracy was only 2.2 percentage points lower than the winner's performance. Furthermore, with subsequent evaluations using 10-fold cross-validation (as given by the organizers) on the combined training and development data, the best average accuracy obtained is 0.8455 and the features that contributed to this accuracy are the TF-IDF of the combined unigrams and bigrams of words.
  • Gebre, B. G., Wittenburg, P., & Heskes, T. (2013). The gesturer is the speaker. In Proceedings of the 38th International Conference on Acoustics, Speech, and Signal Processing (ICASSP 2013) (pp. 3751-3755).

    Abstract

    We present and solve the speaker diarization problem in a novel way. We hypothesize that the gesturer is the speaker and that identifying the gesturer can be taken as identifying the active speaker. We provide evidence in support of the hypothesis from gesture literature and audio-visual synchrony studies. We also present a vision-only diarization algorithm that relies on gestures (i.e. upper body movements). Experiments carried out on 8.9 hours of a publicly available dataset (the AMI meeting data) show that diarization error rates as low as 15% can be achieved.
  • Gebre, B. G., Wittenburg, P., & Lenkiewicz, P. (2012). Towards automatic gesture stroke detection. In N. Calzolari (Ed.), Proceedings of LREC 2012: 8th International Conference on Language Resources and Evaluation (pp. 231-235). European Language Resources Association.

    Abstract

    Automatic annotation of gesture strokes is important for many gesture and sign language researchers. The unpredictable diversity of human gestures and video recording conditions require that we adopt a more adaptive case-by-case annotation model. In this paper, we present a work-in progress annotation model that allows a user to a) track hands/face b) extract features c) distinguish strokes from non-strokes. The hands/face tracking is done with color matching algorithms and is initialized by the user. The initialization process is supported with immediate visual feedback. Sliders are also provided to support a user-friendly adjustment of skin color ranges. After successful initialization, features related to positions, orientations and speeds of tracked hands/face are extracted using unique identifiable features (corners) from a window of frames and are used for training a learning algorithm. Our preliminary results for stroke detection under non-ideal video conditions are promising and show the potential applicability of our methodology.
  • Gentner, D., Ozyurek, A., Gurcanli, O., & Goldin-Meadow, S. (2013). Spatial language facilitates spatial cognition: Evidence from children who lack language input. Cognition, 127, 318-330. doi:10.1016/j.cognition.2013.01.003.

    Abstract

    Does spatial language influence how people think about space? To address this question, we observed children who did not know a conventional language, and tested their performance on nonlinguistic spatial tasks. We studied deaf children living in Istanbul whose hearing losses prevented them from acquiring speech and whose hearing parents had not exposed them to sign. Lacking a conventional language, the children used gestures, called homesigns, to communicate. In Study 1, we asked whether homesigners used gesture to convey spatial relations, and found that they did not. In Study 2, we tested a new group of homesigners on a Spatial Mapping Task, and found that they performed significantly worse than hearing Turkish children who were matched to the deaf children on another cognitive task. The absence of spatial language thus went hand-in-hand with poor performance on the nonlinguistic spatial task, pointing to the importance of spatial language in thinking about space.
  • Gialluisi, A., Incollu, S., Pippucci, T., Lepori, M. B., Zappu, A., Loudianos, G., & Romeo, G. (2013). The homozygosity index (HI) approach reveals high allele frequency for Wilson disease in the Sardinian population. European Journal of Human Genetics, 21, 1308-1311. doi:10.1038/ejhg.2013.43.

    Abstract

    Wilson disease (WD) is an autosomal recessive disorder resulting in pathological progressive copper accumulation in liver and other tissues. The worldwide prevalence (P) is about 30/million, while in Sardinia it is in the order of 1/10 000. However, all of these estimates are likely to suffer from an underdiagnosis bias. Indeed, a recent molecular neonatal screening in Sardinia reported a WD prevalence of 1:2707. In this study, we used a new approach that makes it possible to estimate the allelic frequency (q) of an autosomal recessive disorder if one knows the proportion between homozygous and compound heterozygous patients (the homozygosity index or HI) and the inbreeding coefficient (F) in a sample of affected individuals. We applied the method to a set of 178 Sardinian individuals (3 of whom born to consanguineous parents), each with a clinical and molecular diagnosis of WD. Taking into account the geographical provenance of the parents of every patient within Sardinia (to make F computation more precise), we obtained a q=0.0191 (F=7.8 × 10-4, HI=0.476) and a corresponding prevalence P=1:2732. This result confirms that the prevalence of WD is largely underestimated in Sardinia. On the other hand, the general reliability and applicability of the HI approach to other autosomal recessive disorders is confirmed, especially if one is interested in the genetic epidemiology of populations with high frequency of consanguineous marriages.
  • Gialluisi, A., Pippucci, T., Anikster, Y., Ozbek, U., Medlej-Hashim, M., Mégarbané, A., & Romeo, G. (2012). Estimating the allele frequency of autosomal recessive disorders through mutational records and consanguinity: The homozygosity index (HI). Annals of Human Genetics, 76, 159-167. doi:10.1111/j.1469-1809.2011.00693.x.

    Abstract

    In principle mutational records make it possible to estimate frequencies of disease alleles (q) for autosomal recessive disorders using a novel approach based on the calculation of the Homozygosity Index (HI), i.e., the proportion of homozygous patients, which is complementary to the proportion of compound heterozygous patients P(CH). In other words, the rarer the disorder, the higher will be the HI and the lower will be the P(CH). To test this hypothesis we used mutational records of individuals affected with Familial Mediterranean Fever (FMF) and Phenylketonuria (PKU), born to either consanguineous or apparently unrelated parents from six population samples of the Mediterranean region. Despite the unavailability of precise values of the inbreeding coefficient for the general population, which are needed in the case of apparently unrelated parents, our estimates of q are very similar to those of previous descriptive epidemiological studies. Finally, we inferred from simulation studies that the minimum sample size needed to use this approach is 25 patients either with unrelated or first cousin parents. These results show that the HI can be used to produce a ranking order of allele frequencies of autosomal recessive disorders, especially in populations with high rates of consanguineous marriages.
  • Gialluisi, A., Dediu, D., Francks, C., & Fisher, S. E. (2013). Persistence and transmission of recessive deafness and sign language: New insights from village sign languages. European Journal of Human Genetics, 21, 894-896. doi:10.1038/ejhg.2012.292.

    Abstract

    First paragraph: The study of the transmission of sign languages can give novel insights into the transmission of spoken languages1 and, more generally, into gene–culture coevolution. Over the years, several papers related to the persistence of sign language have been
    reported.2–6 All of these studies have emphasized the role of assortative (non-random) mating by deafness state (ie, a tendency for deaf individuals to partner together) for increasing the frequency of recessive deafness, and hence for the persistence of sign language in a population.
  • Gijssels, T., Bottini, R., Rueschemeyer, S.-A., & Casasanto, D. (2013). Space and time in the parietal cortex: fMRI Evidence for a meural asymmetry. In M. Knauff, M. Pauen, N. Sebanz, & I. Wachsmuth (Eds.), Proceedings of the 35th Annual Meeting of the Cognitive Science Society (CogSci 2013) (pp. 495-500). Austin,TX: Cognitive Science Society. Retrieved from http://mindmodeling.org/cogsci2013/papers/0113/index.html.

    Abstract

    How are space and time related in the brain? This study contrasts two proposals that make different predictions about the interaction between spatial and temporal magnitudes. Whereas ATOM implies that space and time are symmetrically related, Metaphor Theory claims they are asymmetrically related. Here we investigated whether space and time activate the same neural structures in the inferior parietal cortex (IPC) and whether the activation is symmetric or asymmetric across domains. We measured participants’ neural activity while they made temporal and spatial judgments on the same visual stimuli. The behavioral results replicated earlier observations of a space-time asymmetry: Temporal judgments were more strongly influenced by irrelevant spatial information than vice versa. The BOLD fMRI data indicated that space and time activated overlapping clusters in the IPC and that, consistent with Metaphor Theory, this activation was asymmetric: The shared region of IPC was activated more strongly during temporal judgments than during spatial judgments. We consider three possible interpretations of this neural asymmetry, based on 3 possible functions of IPC.
  • Gisladottir, R. S., Chwilla, D., Schriefers, H., & Levinson, S. C. (2012). Speech act recognition in conversation: Experimental evidence. In N. Miyake, D. Peebles, & R. P. Cooper (Eds.), Proceedings of the 34th Annual Meeting of the Cognitive Science Society (CogSci 2012) (pp. 1596-1601). Austin, TX: Cognitive Science Society. Retrieved from http://mindmodeling.org/cogsci2012/papers/0282/index.html.

    Abstract

    Recognizing the speech acts in our interlocutors’ utterances is a crucial prerequisite for conversation. However, it is not a trivial task given that the form and content of utterances is frequently underspecified for this level of meaning. In the present study we investigate participants’ competence in categorizing speech acts in such action-underspecific sentences and explore the time-course of speech act inferencing using a self-paced reading paradigm. The results demonstrate that participants are able to categorize the speech acts with very high accuracy, based on limited context and without any prosodic information. Furthermore, the results show that the exact same sentence is processed differently depending on the speech act it performs, with reading times starting to differ already at the first word. These results indicate that participants are very good at “getting” the speech acts, opening up a new arena for experimental research on action recognition in conversation.
  • Gisselgard, J., Uddén, J., Ingvar, M., & Petersson, K. M. (2007). Disruption of order information by irrelevant items: A serial recognition paradigm. Acta Psychologica, 124(3), 356-369. doi:10.1016/j.actpsy.2006.04.002.

    Abstract

    Irrelevant speech effect (ISE) is defined as a decrement in visually presented digit-list short-term memory performance due to exposure to irrelevant auditory material. Perhaps the most successful theoretical explanation of the effect is the changing state hypothesis. This hypothesis explains the effect in terms of confusion between amodal serial order cues, and represents a view based on the interference caused by the processing of similar order information of the visual and auditory materials. An alternative view suggests that the interference occurs as a consequence of the similarity between the visual and auditory contents of the stimuli. An important argument for the former view is the observation that ISE is almost exclusively observed in tasks that require memory for serial order. However, most short-term memory tasks require that both item and order information be retained in memory. An ideal task to investigate the sensitivity of maintenance of serial order to irrelevant speech would be one that calls upon order information but not item information. One task that is particularly suited to address this issue is serial recognition. In a typical serial recognition task, a list of items is presented and then probed by the same list in which the order of two adjacent items has been transposed. Due to the re-presentation of the encoding string, serial recognition requires primarily the serial order to be maintained while the content of the presented items is deemphasized. In demonstrating a highly significant ISE of changing versus steady-state auditory items in a serial recognition task, the present finding lends support for and extends previous empirical findings suggesting that irrelevant speech has the potential to interfere with the coding of the order of the items to be memorized.
  • Glaser, B., Nikolov, I., Chubb, D., Hamshere, M. L., Segurado, R., Moskvina, V., & Holmans, P. (2007). Analyses of single marker and pairwise effects of candidate loci for rheumatoid arthritis using logistic regression and random forests. BMC Proceedings, 1(Suppl 1): 54.

    Abstract

    Using parametric and nonparametric techniques, our study investigated the presence of single locus and pairwise effects between 20 markers of the Genetic Analysis Workshop 15 (GAW15) North American Rheumatoid Arthritis Consortium (NARAC) candidate gene data set (Problem 2), analyzing 463 independent patients and 855 controls. Specifically, our work examined the correspondence between logistic regression (LR) analysis of single-locus and pairwise interaction effects, and random forest (RF) single and joint importance measures. For this comparison, we selected small but stable RFs (500 trees), which showed strong correlations (r~0.98) between their importance measures and those by RFs grown on 5000 trees. Both RF importance measures captured most of the LR single-locus and pairwise interaction effects, while joint importance measures also corresponded to full LR models containing main and interaction effects. We furthermore showed that RF measures were particularly sensitive to data imputation. The most consistent pairwise effect on rheumatoid arthritis was found between two markers within MAP3K7IP2/SUMO4 on 6q25.1, although LR and RFs assigned different significance levels. Within a hypothetical two-stage design, pairwise LR analysis of all markers with significant RF single importance would have reduced the number of possible combinations in our small data set by 61%, whereas joint importance measures would have been less efficient for marker pair reduction. This suggests that RF single importance measures, which are able to detect a wide range of interaction effects and are computationally very efficient, might be exploited as pre-screening tool for larger association studies. Follow-up analysis, such as by LR, is required since RFs do not indicate highrisk genotype combinations.

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