Publications

Abstract

Serial verb constructions have often been said to refer to single conceptual events. However, evidence to support this claim has been elusive. This article introduces co-speech gestures as a new way of investigating the relationship. The alignment patterns of gestures with serial verb constructions and other complex clauses were compared in Avatime (Ka-Togo, Kwa, Niger-Congo). Serial verb constructions tended to occur with single gestures overlapping the entire construction. In contrast, other complex clauses were more likely to be accompanied by distinct gestures overlapping individual verbs. This pattern of alignment suggests that serial verb constructions are in fact used to describe single events.

Abstract

Elevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci. Experimental downregulation of gene expression in Drosophila melanogaster and Danio rerio identified 20 genes at 11 loci that are relevant for heart rate regulation and highlight a role for genes involved in signal transmission, embryonic cardiac development and the pathophysiology of dilated cardiomyopathy, congenital heart failure and/or sudden cardiac death. In addition, genetic susceptibility to increased heart rate is associated with altered cardiac conduction and reduced risk of sick sinus syndrome, and both heart rate-increasing and heart rate-decreasing variants associate with risk of atrial fibrillation. Our findings provide fresh insights into the mechanisms regulating heart rate and identify new therapeutic targets.

Abstract

Next-generation sequencing is set to transform the discovery of genes underlying neurodevelopmental disorders, and so off er important insights into the biological bases of spoken language. Success will depend on functional assessments in neuronal cell lines, animal models and humans themselves.

Abstract

Prion diseases are fatal neurodegenerative disorders that include Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy in animals. They are unique in terms of their biology because they are caused by the conformational re-arrangement of a normal host-encoded prion protein, PrPC, to an abnormal infectious isoform, PrPSc. Currently the precise mechanism behind prion-mediated neurodegeneration remains unclear. It is hypothesised than an unknown toxic gain of function of PrPSc, or an intermediate oligomeric form, underlies neuronal death. Increasing evidence suggests a role for the ubiquitin proteasome system (UPS) in prion disease. Both wild-type PrPC and disease-associated PrP isoforms accumulate in cells after proteasome inhibition leading to increased cell death, and abnormal beta-sheet-rich PrP isoforms have been shown to inhibit the catalytic activity of the proteasome. Here we review potential interactions between prions and the proteasome outlining how the UPS may be implicated in prion-mediated neurodegeneration.

Abstract

Ependymal cells in the lateral ventricular wall are considered to be post-mitotic but can give rise to neuroblasts and astrocytes after stroke in adult mice due to insult-induced suppression of Notch signaling. The transcription factor FoxJ1, which has been used to characterize mouse ependymal cells, is also expressed by a subset of astrocytes. Cells expressing FoxJ1, which drives the expression of motile cilia, contribute to early postnatal neurogenesis in mouse olfactory bulb. The distribution and progeny of FoxJ1-expressing cells in rat forebrain are unknown. Here we show using immunohistochemistry that the overall majority of FoxJ1-expressing cells in the lateral ventricular wall of adult rats are ependymal cells with a minor population being astrocytes. To allow for long-term fate mapping of FoxJ1-derived cells, we used the piggyBac system for in vivo gene transfer with electroporation. Using this method, we found that FoxJ1-expressing cells, presumably the astrocytes, give rise to neuroblasts and mature neurons in the olfactory bulb both in intact and stroke-damaged brain of adult rats. No significant contribution of FoxJ1-derived cells to stroke-induced striatal neurogenesis was detected. These data indicate that in the adult rat brain, FoxJ1-expressing cells contribute to the formation of new neurons in the olfactory bulb but are not involved in the cellular repair after stroke.

Abstract

Intellectual disability (ID) is a common condition with considerable genetic heterogeneity. Next-generation sequencing of large cohorts has identified an increasing number of genes implicated in ID, but their roles in neurodevelopment remain largely unexplored. Here we report an ID syndrome caused by de novo heterozygous missense, nonsense, and frameshift mutations in BCL11A, encoding a transcription factor that is a putative member of the BAF swi/snf chromatin-remodeling complex. Using a comprehensive integrated approach to ID disease modeling, involving human cellular analyses coupled to mouse behavioral, neuroanatomical, and molecular phenotyping, we provide multiple lines of functional evidence for phenotypic effects. The etiological missense variants cluster in the amino-terminal region of human BCL11A, and we demonstrate that they all disrupt its localization, dimerization, and transcriptional regulatory activity, consistent with a loss of function. We show that Bcl11a haploinsufficiency in mice causes impaired cognition, abnormal social behavior, and microcephaly in accordance with the human phenotype. Furthermore, we identify shared aberrant transcriptional profiles in the cortex and hippocampus of these mouse models. Thus, our work implicates BCL11A haploinsufficiency in neurodevelopmental disorders and defines additional targets regulated by this gene, with broad relevance for our understanding of ID and related syndromes

Abstract

People differ in their ability to perceive second language (L2) sounds. In early bilinguals the variability in learning L2 phonemes stems from speech-specific capabilities (Díaz, Baus, Escera, Costa & Sebastián-Gallés, 2008). The present study addresses whether speech-specific capabilities similarly explain variability in late bilinguals. Event-related potentials were recorded (using a design similar to Díaz et al., 2008) in two groups of late Dutch–English bilinguals who were good or poor in overtly discriminating the L2 English vowels /ε-æ/. The mismatch negativity, an index of discrimination sensitivity, was similar between the groups in conditions involving pure tones (of different length, frequency, and presentation order) but was attenuated in poor L2 perceivers for native, unknown, and L2 phonemes. These results suggest that variability in L2 phonemic learning originates from speech-specific capabilities and imply a continuity of L2 phonemic learning mechanisms throughout the lifespan

Abstract

Retrieval of autobiographical memories is facilitated by activation of perceptuo-motor aspects of the experience, for example a congruent body position at the time of the experiencing and the time of retelling (Dijkstra, Kaschak, & Zwaan, 2007). The present study examined whether similar retrieval facilitation occurs when the direction of motor action is congruent with the valence of emotional memories. Consistent with evidence that people mentally represent emotions spatially (Casasanto, in press), participants moved marbles between vertically stacked boxes at a higher rate when the direction of movement was congruent with the valence of the memory they retrieved (e.g., upward for positive memories, downward for negative memories) than when direction and valence were incongruent (t(22)=4.24, p<.001). In addition, valence-congruent movements facilitated access to these memories, resulting in shorter retrieval times (t(22)=2.43, p<.05). Results demonstrate bidirectional influences between the emotional content of autobiographical memories and irrelevant motor actions.

Abstract

Adherence to medications is an important indicator of the quality of medication management and impacts on health outcomes and cost-effectiveness of healthcare delivery. Electronic healthcare data (EHD) are increasingly used to estimate adherence in research and clinical practice, yet standardization and transparency of data processing are still a concern. Comprehensive and flexible open-source algorithms can facilitate the development of high-quality, consistent, and reproducible evidence in this field. Some EHD-based clinical decision support systems (CDSS) include visualization of medication histories, but this is rarely integrated in adherence analyses and not easily accessible for data exploration or implementation in new clinical settings. We introduce AdhereR, a package for the widely used open-source statistical environment R, designed to support researchers in computing EHD-based adherence estimates and in visualizing individual medication histories and adherence patterns. AdhereR implements a set of functions that are consistent with current adherence guidelines, definitions and operationalizations. We illustrate the use of AdhereR with an example dataset of 2-year records of 100 patients and describe the various analysis choices possible and how they can be adapted to different health conditions and types of medications. The package is freely available for use and its implementation facilitates the integration of medication history visualizations in open-source CDSS platforms.

Abstract

Communication is facilitated when listeners allocate their attention to important information (focus) in the message, a process called "information structure." Linguistic cues like the preceding context and pitch accent help listeners to identify focused information. In multimodal communication, relevant information can be emphasized by nonverbal cues like beat gestures, which represent rhythmic nonmeaningful hand movements. Recent studies have found that linguistic and nonverbal attention cues are integrated independently in single sentences. However, it is possible that these two cues interact when information is embedded in context, because context allows listeners to predict what information is important. In an ERP study, we tested this hypothesis and asked listeners to view videos capturing a dialogue. In the critical sentence, focused and nonfocused words were accompanied by beat gestures, grooming hand movements, or no gestures. ERP results showed that focused words are processed more attentively than nonfocused words as reflected in an N1 and P300 component. Hand movements also captured attention and elicited a P300 component. Importantly, beat gesture and focus interacted in a late time window of 600-900 msec relative to target word onset, giving rise to a late positivity when nonfocused words were accompanied by beat gestures. Our results show that listeners integrate beat gesture with the focus of the message and that integration costs arise when beat gesture falls on nonfocused information. This suggests that beat gestures fulfill a unique focusing function in multimodal discourse processing and that they have to be integrated with the information structure of the message.

Abstract

In this paper we discuss the influence of semantically unexpected information on the prosodic realization of contrast.
For this purpose, we examine the interplay between unexpectedness and various discourse factors that have been claimed to enhance the accentuation of contrastive
information: contrast direction, syntactic status, and discourse distance. We conducted a production experiment in Dutch in which speakers described scenes consisting of moving fruits with unnatural colors. We found that a general cognitive factor such as the unexpectedness of a property has a strong impact on the intonational marking of contrast, over and above the influence of the immediate discourse context.

Abstract

In this paper, we discuss the interplay of factors that influence the intonational marking of contrast in Dutch. In particular, we examine how prominence is expressed at the prosodic level when semantically abnormal information conflicts with contrastive information. For this purpose, we conducted a production experiment in Dutch in which speakers described scenes containing fruits with unnatural colors. We found that semantically abnormal information invokes cognitive prominence which corresponds to intonational prominence. Moreover, the results show that abnormality may overrule the accentual marking of information structural categories such as contrastive focus. If semantically abnormal information becomes integrated into the larger discourse context, its prosodic prominence decreases in favor of the signaling of information structural categories such as contrastive focus.

Abstract

Empirical studies addressing the age factor in second language acquisition have mainly been concerned with a comparison of end state data (from learners before and after the closure of a putative Critical Period for language acquisition) to the native speaker norm. Based on longitudinal corpus data, this paper investigates the affect of age on end state, rate and the process of acquisition and addresses the question of whether different grammatical domains are equally affected. To this end, the paper presents summarized findings from the acquisition of word order and inflectional morphology in L2 German by Russian learners of different ages and discusses theoretical implications that can be drawn from this evidence.

Abstract

It is widely assumed that ultimate attainment in adult second language (L2) learners often differs quite radically from ultimate attainment in child L2 learners. This article addresses the question of whether learners at different ages also show qualitative differences in the process of L2 acquisition. Longitudinal production data from two untutored Russian beginners (ages 8 and 14) acquiring German under roughly similar conditions are compared to published results on the acquisition of German by adult immigrants. The study focuses on the acquisition of negation and finiteness as core domains of German sentence grammar. Adult learners have been shown to produce an early nonfinite learner variety in which utterance organization relies on principles of information structure rather than on target language grammar. They then go through a couple of intermediate steps in which, first, semantically empty verbs (auxiliaries) serve as isolated carriers of finiteness before lexical verbs become finite. Whereas the 14-year-old learner of this case study basically shows a developmental pattern similar to that of adults, the 8-year-old child produces a different order of acquisition: Not only is the development of finite morphology faster, but finite lexical verbs are acquired before auxiliary constructions (Perfekt). Results suggest a stronger tendency for young learners to incrementally assimilate input patterns without relying on analytic steps guided by principles of information organization to the same extent as older learners.

Abstract

Words evolve not as blobs of ink on paper but in face to face interaction. The nature of language as fundamentally interactive and multimodal is shown by the study of ideophones, vivid sensory words that thrive in conversations around the world. The ways in which these Lautbilder enable precise communication about sensory knowledge has for the first time been studied in detail. It turns out that we can paint with language, and that the onomatopoeia we sometimes classify as childish might be a subset of a much richer toolkit for depiction in speech, available to us all.

Abstract

We provide an annotated coding scheme for other-initiated repair, along with guidelines for building collections and aggregating cases based on interactionally relevant similarities and differences. The questions and categories of the scheme are grounded in inductive observations of conversational data and connected to a rich body of work on other-initiated repair in conversation analysis. The scheme is developed and tested in a 12-language comparative project and can serve as a stepping stone for future work on other-initiated repair and the systematic comparative study of conversational structures.

Abstract

This entry provides some orientation and task suggestions on how to explore the perceptual world of your field site and the interaction between the cultural world and the sensory lexicon in your community. The material consists of procedural texts; soundscapes; other documentary and observational tasks. The goal of this task is to explore the perceptual world of your field site and the interaction between the cultural world and the sensory lexicon in your community.

Abstract

This article examines the relation between ideophones and gestures in a corpus of everyday discourse in Siwu, a richly ideophonic language spoken in Ghana. The overall frequency of ideophone-gesture couplings in everyday speech is lower than previously suggested, but two findings shed new light on the relation between ideophones and gesture. First, discourse type makes a difference: ideophone-gesture couplings are more frequent in narrative contexts, a finding that explains earlier claims, which were based not on everyday language use but on elicited narratives. Second, there is a particularly strong coupling between ideophones and one type of gesture: iconic gestures. This coupling allows us to better understand iconicity in relation to the affordances of meaning and modality. Ultimately, the connection between ideophones and iconic gestures is explained by reference to the depictive nature of both. Ideophone and iconic gesture are two aspects of the process of depiction

Abstract

A word like Huh?–used as a repair initiator when, for example, one has not clearly heard what someone just said– is found in roughly the same form and function in spoken languages across the globe. We investigate it in naturally occurring conversations in ten languages and present evidence and arguments for two distinct claims: that Huh? is universal, and that it is a word. In support of the first, we show that the similarities in form and function of this interjection across languages are much greater than expected by chance. In support of the second claim we show that it is a lexical, conventionalised form that has to be learnt, unlike grunts or emotional cries. We discuss possible reasons for the cross-linguistic similarity and propose an account in terms of convergent evolution. Huh? is a universal word not because it is innate but because it is shaped by selective pressures in an interactional environment that all languages share: that of other-initiated repair. Our proposal enhances evolutionary models of language change by suggesting that conversational infrastructure can drive the convergent cultural evolution of linguistic items.

Abstract

Sound symbolism is a phenomenon with broad relevance to the study of language and mind, but there has been a disconnect between its investigations in linguistics and psychology. This study tests the sound-symbolic potential of ideophones—words described as iconic—in an experimental task that improves over prior work in terms of ecological validity and experimental control. We presented 203 ideophones from five languages to eighty-two Dutch listeners in a binary-choice task, in four versions: original recording, full diphone resynthesis, segments-only resynthesis, and prosody-only resynthesis. Listeners guessed the meaning of all four versions above chance, confirming the iconicity of ideophones and showing the viability of speech synthesis as a way of controlling for segmental and suprasegmental properties in experimental studies of sound symbolism. The success rate was more modest than prior studies using pseudowords like bouba/kiki, implying that assumptions based on such words cannot simply be transferred to natural languages. Prosody and segments together drive the effect: neither alone is sufficient, showing that segments and prosody work together as cues supporting iconic interpretations. The findings cast doubt on attempts to ascribe iconic meanings to segments alone and support a view of ideophones as words that combine arbitrariness and iconicity.We discuss the implications for theory and methods in the empirical study of sound symbolism and iconicity.

Abstract

This thesis examines the semantic structures underlying the encoding of space in Chintang, a Kiranti (Sino-Tibetan) language of Nepal. It provides a short general introduction to the history of thinking and speaking about space as well as to the notions of deixis and transposition, and sketches a state-of-the-art theory for categorizing spatial semantics (Levinson 2003). Drawing on targeted elicitation with native speakers, the empirical part then relates linguistic items of Chintang to the theoretical framework, with a focus on the nominal domain. After an analysis of deictic, topological, intrinsic and absolute spatial relations and their reflections in the language, the investigation concludes by comparing sets of Chintang deictics to those found in neighbouring Belhare (Bickel 2001). Despite striking formal resemblances, the semantic differences found indicate that even across closely related languages, meaning does not generalize easily.

Abstract

Under what circumstances do languages die? Why has their “mortality rate” increased dramatically in the recent past? What “causes of death” can be identified for historical cases, to what extent are these generalizable, and how can they be captured in an explanatory theory? In pursuing these questions, it becomes apparent that in typical cases of language death various causes tend to interact in multiple ways. Speakers’ attitudes towards their language play a critical role in all of this. Existing categorial taxonomies do not succeed in modeling the complex relationships between these factors. Therefore, an alternative, dimensional approach is called for to more adequately address (and counter) the causes of language death in a given scenario.

Abstract

Background Sanger sequencing, still the standard technique for genetic testing in most diagnostic laboratories and until recently widely used in research, is gradually being complemented by next-generation sequencing (NGS). No single mutation detection technique is however perfect in identifying all mutations. Therefore, we wondered to what extent inconsistencies between Sanger sequencing and NGS affect the molecular diagnosis of patients. Since mutations in SCN1A, the major gene implicated in epilepsy, are found in the majority of Dravet syndrome (DS) patients, we focused on missed SCN1A mutations. Methods We sent out a survey to 16 genetic centers performing SCN1A testing. Results We collected data on 28 mutations initially missed using Sanger sequencing. All patients were falsely reported as SCN1A mutation-negative, both due to technical limitations and human errors. Conclusion We illustrate the pitfalls of Sanger sequencing and most importantly provide evidence that SCN1A mutations are an even more frequent cause of DS than already anticipated.

Abstract

Spatial congruity effects have often been interpreted as evidence for metaphorical thinking, but an alternative markedness-based account challenges this view. In two experiments, we directly compared metaphor and markedness explanations for spatial congruity effects, using musical pitch as a testbed. English speakers who talk about pitch in terms of spatial height were tested in speeded space-pitch compatibility tasks. To determine whether space-pitch congruency effects could be elicited by any marked spatial continuum, participants were asked to classify high- and low-frequency pitches as 'high' and 'low' or as 'front' and 'back' (both pairs of terms constitute cases of marked continuums). We found congruency effects in high/low conditions but not in front/back conditions, indicating that markedness is not sufficient to account for congruity effects (Experiment 1). A second experiment showed that congruency effects were specific to spatial words that cued a vertical schema (tall/short), and that congruity effects were not an artifact of polysemy (e.g., 'high' referring both to space and pitch). Together, these results suggest that congruency effects reveal metaphorical uses of spatial schemas, not markedness effects.

Abstract

Do people who speak different languages think differently, even when they are not using language? To find out, we used nonlinguistic psychophysical tasks to compare mental representations of musical pitch in native speakers of Dutch and Farsi. Dutch speakers describe pitches as high (hoog) or low (laag), whereas Farsi speakers describe pitches as thin (na-zok) or thick (koloft). Differences in language were reflected in differences in performance on two pitch-reproduction tasks, even though the tasks used simple, nonlinguistic stimuli and responses. To test whether experience using language influences mental representations of pitch, we trained native Dutch speakers to describe pitch in terms of thickness, as Farsi speakers do. After the training, Dutch speakers’ performance on a nonlinguistic psychophysical task resembled the performance of native Farsi speakers. People who use different linguistic space-pitch metaphors also think about pitch differently. Language can play a causal role in shaping nonlinguistic representations of musical pitch.

Abstract

Abstract mental representation is fundamental for human cognition. Forming such representations in time, especially from dynamic and noisy perceptual input, is a challenge for any processing modality, but perhaps none so acutely as for language processing. We show that LISA (Hummel & Holyaok, 1997) and DORA (Doumas, Hummel, & Sandhofer, 2008), models built to process and to learn structured (i.e., symbolic) rep resentations of conceptual properties and relations from unstructured inputs, show oscillatory activation during processing that is highly similar to the cortical activity elicited by the linguistic stimuli from Ding et al.(2016). We argue, as Ding et al.(2016), that this activation reflects formation of hierarchical linguistic representation, and furthermore, that the kind of computational mechanisms in LISA/DORA (e.g., temporal binding by systematic asynchrony of firing) may underlie formation of abstract linguistic representations in the human brain. It may be this repurposing that allowed for the generation or mergence of hierarchical linguistic structure, and therefore, human language, from extant cognitive and neural systems. We conclude that models of thinking and reasoning and models of language processing must be integrated —not only for increased plausiblity, but in order to advance both fields towards a larger integrative model of human cognition

Abstract

The Levelt, Noort and Drenth Committees make their sole and final rejoinder to criticisms of their report on the Stapel fraud

Abstract

Reduced forms like yeshay for yesterday often occur in conversations. Previous behavioral research reported a processing advantage for full over reduced forms. The present study investigated whether this processing advantage is reflected in a modulation of alpha (8–12 Hz) and gamma (30+ Hz) band activity. In three electrophysiological experiments, participants listened to full and reduced forms in isolation (Experiment 1), sentence-final position (Experiment 2), or mid-sentence position (Experiment 3). Alpha power was larger in response to reduced forms than to full forms, but only in Experiments 1 and 2. We interpret these increases in alpha power as reflections of higher auditory cognitive load. In all experiments, gamma power only increased in response to full forms, which we interpret as showing that lexical activation spreads more quickly through the semantic network for full than for reduced forms. These results confirm a processing advantage for full forms, especially in non-medial sentence position.

Abstract

There is ample evidence that native and non-native listeners use lexical knowledge to retune their native phonetic categories following ambiguous pronunciations. The present study investigates whether a non-native ambiguous sound can retune non-native phonetic categories. After a brief exposure to an ambiguous British English [l/ɹ] sound, Dutch listeners demonstrated retuning. This retuning was, however, asymmetrical: the non-native listeners seemed to show (more) retuning of the /ɹ/ category than of the /l/ category, suggesting that non-native listeners can retune non-native phonetic categories. This asymmetry is argued to be related to the large phonetic variability of /r/ in both Dutch and English.

Abstract

Listeners use their lexical knowledge to interpret ambiguous sounds, and retune their phonetic categories to include this ambiguous sound. Although there is ample evidence for lexically-guided retuning, the adaptation process is not fully understood. Using a lexical decision task with an embedded auditory semantic priming task, the present study investigates whether words containing an ambiguous sound are processed in the same way as “natural” words and whether adaptation to the ambiguous sound tends to equalize the processing of “ambiguous” and natural words. Analyses of the yes/no responses and reaction times to natural and “ambiguous” words showed that words containing an ambiguous sound were accepted as words less often and were processed slower than the same words without ambiguity. The difference in acceptance disappeared after exposure to approximately 15 ambiguous items. Interestingly, lower acceptance rates and slower processing did not have an effect on the processing of semantic information of the following word. However, lower acceptance rates of ambiguous primes predict slower reaction times of these primes, suggesting an important role of stimulus-specific characteristics in triggering lexically-guided perceptual learning.

Abstract

Der vorliegende Beitrag zum Kieler Symposium1 stellt die Resultate eines Teilbereichs meiner Arbeit zum Guarani vor, nämlich einen Vorschlag zur Analyse der Personenpräfixe dieser Sprache und der mit ihnen verbundenen grammatischen Kategorien. Die im Titel angedeutete lexikographische Fragestellung bedarf einer näheren Erläuterung, die ich im Zusammenhang mit einer kurzen Darstellung der Motivation für meine Untersuchungen geben will

Abstract

With the present essay I pursue a threefold aim as will be explained in the following paragraphs. Since I cannot expect my readers to be familiar with the language studied, Guaran´ı, more information about this language will be given in the next subsection.

Abstract

1. Object: Awetí and the ‘Mawetí-Guaraní’ subfamily “Mawetí-Guaraní” is a shorter designation of a branch of the large Tupí language family, alongside with eight other branches or subfamilies. This branch in turn consists internally of the languages (Sateré-) Mawé and Awetí and the large Tupí-Guaraní subfamily, and so its explicit but longish name could be “Mawé-Awetí-Tupí-Guaraní” (MTAG). This genetic grouping has already been suggested (without any specific designation) by A. D. Rodrigues (e.g., 1984/85; Rodrigues and Dietrich 1997), and, more recently, it has been confirmed by comparative studies (Corrêa da Silva 2007; Drude 2006; Meira and Drude in prep.), which also more reliably establish the most probable internal ramification, according to which Mawé separated first, whereas the differentiation between Awetí, on the one hand, and the precursor of the Tupí-Guaraní (TG) subfamily, proto-Tupí-Guaraní (pTG), on the other, would have been more recent. The intermediate branch could be named “Awetí-Tupí-Guaraní” (“Awetí-TG” or “ATG”). Figure 1 shows the internal grouping of the Tupí family according to results of the Tupí Comparative Project under D. Moore at the Museu Goeldi (2000–2006).

Abstract

This paper describes the verbal Tense-Aspect-Mood system of Awetí (Tupian, Central Brazil) in a Word-and-Paradigm approach. One classification of Awetí verb forms contains clear aspect categories. A second set of independent classifications renders at least four moods and contains a third major TAM classification, factuality, that has one mainly temporal category Future, while others are partially or wholly modal. Structural categories reflect the formal composition of the forms. Some forms are synthetic, ‘marked’ only by means of affixes, but many are analytic, containing auxiliary particles. With selected sample forms we demonstrate in detail the interplay of structural and functional categories in Awetí verb paradigms.

Abstract

Using various methods derived from evolutionary biology, including maximum parsimony and Bayesian phylogenetic analysis, we tackle the question of the relationships among a group of Papuan isolate languages that have hitherto resisted accepted attempts at demonstration of interrelatedness. Instead of using existing vocabulary-based methods, which cannot be applied to these languages due to the paucity of shared lexemes, we created a database of STRUCTURAL FEATURES—abstract phonological and grammatical features apart from their form. The methods are first tested on the closely related Oceanic languages spoken in the same region as the Papuan languages in question. We find that using biological methods on structural features can recapitulate the results of the comparative method tree for the Oceanic languages, thus showing that structural features can be a valid way of extracting linguistic history. Application of the same methods to the otherwise unrelatable Papuan languages is therefore likely to be similarly valid. Because languages that have been in contact for protracted periods may also converge, we outline additional methods for distinguishing convergence from inherited relatedness.

Abstract

The Aslian branch of Austroasiatic is recognised as the oldest recoverable language family in the Malay Peninsula, predating the now dominant Austronesian languages present today. In this paper we address the dynamics of the prehistoric spread of Aslian languages across the peninsula, including the languages spoken by Semang foragers, traditionally associated with the 'Negrito' phenotype. The received view of an early and uniform tripartite break-up of proto-Aslian in the Early Neolithic period, and subsequent differentiation driven by societal modes is challenged. We present a Bayesian phylogeographic analysis of our dataset of vocabulary from 28 Aslian varieties. An explicit geographic model of diffusion is combined with a cognate birth-word death model of lexical evolution to infer the location of the major events of Aslian cladogenesis. The resultant phylogenetic trees are calibrated against dates in the historical and archaeological record to extrapolate a detailed picture of Aslian language history. We conclude that a binary split between Southern Aslian and the rest of Aslian took place in the Early Neolithic (4000 BP). This was followed much later in the Late Neolithic (2000-3000 BP) by a tripartite branching into Central Aslian, Jah Hut and Northern Aslian. Subsequent internal divisions within these sub-clades took place in the Early Metal Phase (post-2000 BP). Significantly, a split in Northern Aslian between Ceq Wong and the languages of the Semang was a late development and is proposed here to coincide with the adoption of Aslian by the Semang foragers. Given the difficulties involved in associating archaeologically recorded activities with linguistic events, as well as the lack of historical sources, our results remain preliminary. However, they provide sufficient evidence to prompt a rethinking of previous models of both clado- and ethno-genesis within the Malay Peninsula.

Abstract

In recent years, large scale initiatives like CLARIN set out to overcome the notorious heterogeneity of metadata formats in the domain of language resource. The CLARIN Component Metadata Infrastructure established means for flexible resouce descriptions for the domain of language resources. The Data Category Registry ISOcat and the accompanying Relation Registry foster semantic interoperability within the growing heterogeneous collection of metadata records. This paper describes the CMD Infrastructure focusing on the facilities for semantic mapping, and gives also an overview of the current status in the joint component metadata domain.

Abstract

The Core Trustworthy Data Repository Requirements were developed by the DSA–WDS Partnership Working Group on Repository Audit and Certification, a Working Group (WG) of the Research Data Alliance . The goal of the effort was to create a set of harmonized common requirements for certification of repositories at the core level, drawing from criteria already put in place by the Data Seal of Approval (DSA: www.datasealofapproval.org) and the ICSU World Data System (ICSU-WDS: https://www.icsu-wds.org/services/certification). An additional goal of the project was to develop common procedures to be implemented by both DSA and ICSU-WDS. Ultimately, the DSA and ICSU-WDS plan to collaborate on a global framework for repository certification that moves from the core to the extended (nestor-Seal DIN 31644), to the formal (ISO 16363) level.

Abstract

Written and verbal languages are neurobehavioral traits vital to the development of communication skills. Unfortunately, disorders involving these traits-specifically reading disability (RD) and language impairment (LI)-are common and prevent affected individuals from developing adequate communication skills, leaving them at risk for adverse academic, socioeconomic and psychiatric outcomes. Both RD and LI are complex traits that frequently co-occur, leading us to hypothesize that these disorders share genetic etiologies. To test this, we performed a genome-wide association study on individuals affected with both RD and LI in the Avon Longitudinal Study of Parents and Children. The strongest associations were seen with markers in ZNF385D (OR = 1.81, P = 5.45 × 10(-7) ) and COL4A2 (OR = 1.71, P = 7.59 × 10(-7) ). Markers within NDST4 showed the strongest associations with LI individually (OR = 1.827, P = 1.40 × 10(-7) ). We replicated association of ZNF385D using receptive vocabulary measures in the Pediatric Imaging Neurocognitive Genetics study (P = 0.00245). We then used diffusion tensor imaging fiber tract volume data on 16 fiber tracts to examine the implications of replicated markers. ZNF385D was a predictor of overall fiber tract volumes in both hemispheres, as well as global brain volume. Here, we present evidence for ZNF385D as a candidate gene for RD and LI. The implication of transcription factor ZNF385D in RD and LI underscores the importance of transcriptional regulation in the development of higher order neurocognitive traits. Further study is necessary to discern target genes of ZNF385D and how it functions within neural development of fluent language.

Abstract

How involved in an event is a person that possesses one of the event participants? Some languages can treat such “external possessors” as very closely involved, even marking them on the verb along with core roles such as subject and object. Other languages only allow possessors to be expressed as non-core participants. This task explores possibilities for the encoding of possessors and other related roles such as beneficiaries. The materials consist of a sequence of thirty drawings designed to elicit target construction types.

Abstract

Migraine is a disabling common brain disorder typically characterized by attacks of severe headache and associated with autonomic and neurological symptoms. Its etiology is far from resolved. This review will focus on evidence that epigenetic mechanisms play an important role in disease etiology. Epigenetics comprise both DNA methylation and post-translational modifications of the tails of histone proteins, affecting chromatin structure and gene expression. Besides playing a role in establishing cellular and developmental stage-specific regulation of gene expression, epigenetic processes are also important for programming lasting cellular responses to environmental signals. Epigenetic mechanisms may explain how non-genetic endogenous and exogenous factors such as female sex hormones, stress hormones and inflammation trigger may modulate attack frequency. Developing drugs that specifically target epigenetic mechanisms may open up exciting new avenues for the prophylactic treatment of migraine.

Abstract

Migraine is a common disabling neurovascular brain disorder typically characterised by attacks of severe headache and associated with autonomic and neurological symptoms. Migraine is caused by an interplay of genetic and environmental factors. Genome-wide association studies (GWAS) have identified over a dozen genetic loci associated with migraine. Here, we integrated migraine GWAS data with high-resolution spatial gene expression data of normal adult brains from the Allen Human Brain Atlas to identify specific brain regions and molecular pathways that are possibly involved in migraine pathophysiology. To this end, we used two complementary methods. In GWAS data from 23,285 migraine cases and 95,425 controls, we first studied modules of co-expressed genes that were calculated based on human brain expression data for enrichment of genes that showed association with migraine. Enrichment of a migraine GWAS signal was found for five modules that suggest involvement in migraine pathophysiology of: (i) neurotransmission, protein catabolism and mitochondria in the cortex; (ii) transcription regulation in the cortex and cerebellum; and (iii) oligodendrocytes and mitochondria in subcortical areas. Second, we used the high-confidence genes from the migraine GWAS as a basis to construct local migraine-related co-expression gene networks. Signatures of all brain regions and pathways that were prominent in the first method also surfaced in the second method, thus providing support that these brain regions and pathways are indeed involved in migraine pathophysiology.

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Migraine is a common episodic brain disorder characterized by recurrent attacks of severe unilateral headache and additional neurological symptoms. Two main migraine types can be distinguished based on the presence of aura symptoms that can accompany the headache: migraine with aura and migraine without aura. Multiple genetic and environmental factors confer disease susceptibility. Recent genome-wide association studies (GWAS) indicate that migraine susceptibility genes are involved in various pathways, including neurotransmission, which have already been implicated in genetic studies of monogenic familial hemiplegic migraine, a subtype of migraine with aura. Methods To further explore the genetic background of migraine, we performed a gene set analysis of migraine GWAS data of 4954 clinic-based patients with migraine, as well as 13,390 controls. Curated sets of synaptic genes and sets of genes predominantly expressed in three glial cell types (astrocytes, microglia and oligodendrocytes) were investigated. Discussion Our results show that gene sets containing astrocyte- and oligodendrocyte-related genes are associated with migraine, which is especially true for gene sets involved in protein modification and signal transduction. Observed differences between migraine with aura and migraine without aura indicate that both migraine types, at least in part, seem to have a different genetic background.

Abstract

Purpose of review: Migraine is a prevalent neurovascular brain disorder with a strong genetic component, and different methodological approaches have been implemented to identify the genes involved. This review focuses on pearls and pitfalls of these approaches and genetic findings in migraine. Summary: Common forms of migraine (i.e. migraine with and without aura) are thought to have a polygenic make-up, whereas rare familial hemiplegic migraine (FHM) presents with a monogenic pattern of inheritance. Until a few years ago only studies in FHM yielded causal genes, which were identified by a classical linkage analysis approach. Functional analyses of FHM gene mutations in cellular and transgenic animal models suggest abnormal glutamatergic neurotransmission as a possible key disease mechanism. Recently, a number of genes were discovered for the common forms of migraine using a genome-wide association (GWA) approach, which sheds first light on the pathophysiological mechanisms involved. Conclusions: Novel technological strategies such as next-generation sequencing, which can be implemented in future genetic migraine research, may aid the identification of novel FHM genes and promote the search for the missing heritability of common migraine.

Abstract

We conducted four experiments to investigate the specificity of perceptual adjustments made to unusual speech sounds. Dutch listeners heard a female talker produce an ambiguous fricative [?] (between [f] and [s]) in [f]- or [s]-biased lexical contexts. Listeners with [f]-biased exposure (e.g., [witlo?]; from witlof, “chicory”; witlos is meaningless) subsequently categorized more sounds on an [εf]–[εs] continuum as [f] than did listeners with [s]-biased exposure. This occurred when the continuum was based on the exposure talker's speech (Experiment 1), and when the same test fricatives appeared after vowels spoken by novel female and male talkers (Experiments 1 and 2). When the continuum was made entirely from a novel talker's speech, there was no exposure effect (Experiment 3) unless fricatives from that talker had been spliced into the exposure talker's speech during exposure (Experiment 4). We conclude that perceptual learning about idiosyncratic speech is applied at a segmental level and is, under these exposure conditions, talker specific.

Abstract

The perception of speech sounds can be re-tuned rapidly through a mechanism of lexically-driven learning (Norris et al 2003, Cogn.Psych. 47). Here we investigated this type of learning for English voiced stop consonants which are commonly de-voiced in word final position by Dutch learners of English . Specifically, this study asked under which conditions the change in pre-lexical representation encodes phonological information about the position of the critical sound within a word. After exposure to a Dutch learner’s productions of de-voiced stops in word-final position (but not in any other positions), British English listeners showed evidence of perceptual learning in a subsequent cross-modal priming task, where auditory primes with voiceless final stops (e.g., ‘seat’), facilitated recognition of visual targets with voiced final stops (e.g., SEED). This learning generalized to test pairs where the critical contrast was in word-initial position, e.g. auditory primes such as ‘town’ facilitated recognition of visual targets like DOWN (Experiment 1). Control listeners, who had not heard any stops by the speaker during exposure, showed no learning effects. The generalization to word-initial position did not occur when participants had also heard correctly voiced, word-initial stops during exposure (Experiment 2), and when the speaker was a native BE speaker who mimicked the word-final devoicing (Experiment 3). These results suggest that word position can be encoded in the pre-lexical adjustment to the accented phoneme contrast. Lexcially-guided feedback, distributional properties of the input, and long-term representations of accents all appear to modulate the pre-lexical re-tuning of phoneme categories.

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Central to cultural, social, and conceptual life are cognitive arti-facts, the perceptible structures which populate our world and mediate our navigation of it, complementing, enhancing, and altering available affordances for the problem-solving challenges of everyday life. Much work in this domain has concentrated on technological artifacts, especially manual tools and devices and the conceptual and communicative tools of literacy and diagrams. Recent research on hand gestures and other bodily movements which occur during speech shows that the human body serves a number of the functions of "cognitive technologies," affording the special cognitive advantages claimed to be associated exclusively with enduring (e.g., printed or drawn) diagrammatic representations. The issue is explored with reference to extensive data from video-recorded interviews with speakers of Lao in Vientiane, Laos, which show integration of verbal descriptions with complex spatial representations akin to diagrams. The study has implications both for research on cognitive artifacts (namely, that the body is a visuospatial representational resource not to be overlooked) and for research on ethnogenealogical knowledge (namely, that hand gestures reveal speakers' conceptualizations of kinship structure which are of a different nature to and not necessarily retrievable from the accompanying linguistic code).

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To develop a nuanced account for selection within an epidemiological, population-based model of language contact and change, it is useful to consider possible conduits and filters on linguistic transmission and distribution. Richerson & Boyd (2005) describe a number of candidate biases in their evolutionary analysis of culture as a biological phenomenon (cf. Cavalli-Sforza & Feldman 1981, Sperber 1985, 1999, Boyd & Richerson 2005). This paper explores some of these biases with reference to language, exploring a set of analytic distinctions for a proper understanding of population-level linguistic processes. In putting forward these ideas, this paper echoes recent attempts to combine linguistic and biological concepts in the analysis of language diversity and change.

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This field guide is for eliciting information about grammatical resources used in describing perceptual events and perception-based properties and states. A list of leading questions outlines an underlying semantic space for events/states of perception, against which language-specific constructions may be defined. It should be used as an entry point into a flexible exploration of the structures and constraints which are specific to the language you are working on. The goal is to provide a cross-linguistically comparable description of the constructions of a language used in describing perceptual events and states. The core focus is to discover any sensory asymmetries, i.e., ways in which different sensory modalities are treated differently with respect to these constructions.

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Different domains of concrete referential semantics have provided testing grounds for investigation of the differential roles of perception, cognition, language, and culture in human categorization. A vast literature on semantics of biological classification, color, shape and topological relations, artifacts, and more, raises a range of theoretical and analytical debates. This article uses landscape terms to address a key debate from within research on ethnobiological classification: the opposition between so-called utilitarian and intellectualist accounts for patterns of lexicalization of the natural world [Berlin, B., 1992. Ethnobiological Classification: Principles of Categorization of Plants and Animals in Traditional Societies. Princeton University Press, Princeton, NJ]. ‘Utilitarianists’ argue that lexical categories reflect practical consequences of knowing certain category distinctions, related to cultural practice and functional affordances of referents. ‘Intellectualists’ argue that lexical categories reflect people’s innate interest in the natural world, combined with the perceptual discontinuities supplied by ‘Nature’s Plan’. The debate is generalizable to other domains, including landscape terminology, the topic of this special issue. This article brings landscape terminology into this larger debate, arguing in favor of a utilitarian account of linguistic categories in the domain of landscape, but proposing a significant revision to the concept of utility in linguistic categorization. The proposal is that for linguistic categorization, what is at issue is not (primarily) the utility of the referent (e.g. a river), but the utility of the word (e.g. the English word river). By considering how landscape terms are actually used in conversation, we see that they are deployed in communicative contexts which fit a rich, ‘functionalist’ semantics. A landscape term is not employed for mere referring, but functions to bring particular associated ideas into social discourse. In turn, language use reveals a range of evidence for the semantic content of any such term, of utility both to the language learner and to the semanticist. This kind of evidence can be argued to underlie the acquisition of semantic categories in language learning. The arguments are illustrated with examples from Lao, a Tai language of mainland Southeast Asia.

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Language is shaped by its environment, which includes not only the brain, but also the public context in which speech acts are effected. To fully account for why language has the shape it has, we need to examine the constraints imposed by language use as a sequentially organized joint activity, and as the very conduit for linguistic diffusion and change.

Abstract

Introduction

A comparison of conversation in twenty-one languages from around the world reveals commonalities and differences in the way that people do open-class other-initiation of repair (Schegloff, Jefferson, and Sacks, 1977; Drew, 1997). We find that speakers of all of the spoken languages in the sample make use of a primary interjection strategy (in English it is Huh?), where the phonetic form of the interjection is strikingly similar across the languages: a monosyllable featuring an open non-back vowel [a, æ, ə, ʌ], often nasalized, usually with rising intonation and sometimes an [h-] onset. We also find that most of the languages have another strategy for open-class other-initiation of repair, namely the use of a question word (usually “what”). Here we find significantly more variation across the languages. The phonetic form of the question word involved is completely different from language to language: e.g., English [wɑt] versus Cha'palaa [ti] versus Duna [aki]. Furthermore, the grammatical structure in which the repair-initiating question word can or must be expressed varies within and across languages. In this chapter we present data on these two strategies – primary interjections like Huh? and question words like What? – with discussion of possible reasons for the similarities and differences across the languages. We explore some implications for the notion of repair as a system, in the context of research on the typology of language use.

The general outline of this chapter is as follows. We first discuss repair as a system across languages and then introduce the focus of the chapter: open-class other-initiation of repair. A discussion of the main findings follows, where we identify two alternative strategies in the data: an interjection strategy (Huh?) and a question word strategy (What?). Formal features and possible motivations are discussed for the interjection strategy and the question word strategy in order. A final section discusses bodily behavior including posture, eyebrow movements and eye gaze, both in spoken languages and in a sign language.

Abstract

People of all cultures have some degree of concern with categorizing types of communicative social action. All languages have words with meanings like speak, say, talk, complain, curse, promise, accuse, nod, wink, point and chant. But the exact distinctions they make will differ in both quantity and quality. How is communicative social action categorised across languages and cultures? The goal of this task is to establish a basis for cross-linguistic comparison of native metalanguages for social action.

Abstract

The study of language in relation to anthropological questions has deep and varied roots, from Humboldt and Boas, Malinowski and Vygotsky, Sapir and Whorf, Wittgenstein and Austin, through to the linguistic anthropologists of now. A recent book by the linguist Daniel Everett, language: the cultural tool (2012), aims to bring some of the issues to a popular audience, with a focus on the idea that language is a tool for social action. I argue in this essay that the book does not represent the state of the art in this field, falling short on three central desiderata of a good account for the social functions of language and its relation to culture. I frame these desiderata in terms of three questions, here termed the cognition question, the causality question, and the culture question. I look at the relevance of this work for socio-cultural anthropology, in the context of a major interdisciplinary pendulum swing that is incipient in the study of language today, a swing away from formalist, innatist perspectives, and towards functionalist, empiricist perspectives. The role of human diversity and culture is foregrounded in all of this work. To that extent, Everett’s book is representative, but the quality of his argument is neither strong in itself nor representative of a movement that ought to be of special interest to socio-cultural anthropologists.

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This chapter contains sections titled: Introduction Lexical Selection in Reference: Introductory Examples of Reference to Times Multiple “Preferences” Future Directions Conclusion

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This Field Manual entry has been superceded by the 2009 version: https://doi.org/10.17617/2.883564

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Review of the books "Virtually you. The dangerous powers of the e-personality", by Elias Aboujaoude; "The big disconnect. The story of technology and loneliness", by Giles Slade; and "Net smart. How to thrive online", by Howard Rheingold.

Abstract

Listeners show a remarkable ability to quickly adjust to degraded speech input. Here, we aimed to identify the neural mechanisms of such short-term perceptual adaptation. In a sparse-sampling, cardiac-gated functional magnetic resonance imaging (fMRI) acquisition, human listeners heard and repeated back 4-band-vocoded sentences (in which the temporal envelope of the acoustic signal is preserved, while spectral information is highly degraded). Clear-speech trials were included as baseline. An additional fMRI experiment on amplitude modulation rate discrimination quantified the convergence of neural mechanisms that subserve coping with challenging listening conditions for speech and non-speech. First, the degraded speech task revealed an “executive” network (comprising the anterior insula and anterior cingulate cortex), parts of which were also activated in the non-speech discrimination task. Second, trial-by-trial fluctuations in successful comprehension of degraded speech drove hemodynamic signal change in classic “language” areas (bilateral temporal cortices). Third, as listeners perceptually adapted to degraded speech, downregulation in a cortico-striato-thalamo-cortical circuit was observable. The present data highlight differential upregulation and downregulation in auditory–language and executive networks, respectively, with important subcortical contributions when successfully adapting to a challenging listening situation.

Abstract

This study addresses the extent to which the location of primary stress in Dutch, German, and English monomorphemic words is affected by the syllables preceding the three final syllables. We present analyses of the monomorphemic words in the CELEX lexical database, which showed that penultimate primary stress is less frequent in Dutch and English trisyllabic than quadrisyllabic words. In addition, we discuss paper-and-pencil experiments in which native speakers assigned primary stress to pseudowords. These experiments provided evidence that in all three languages penultimate stress is more likely in quadrisyllabic than in trisyllabic words. We explain this length effect with the preferences in these languages for word-initial stress and for alternating patterns of stressed and unstressed syllables. The experimental data also showed important intra- and interspeaker variation, and they thus form a challenging test case for theories of language variation.

Abstract

Previous research has shown that the production of morphologically complex words in isolation is affected by the properties of morphologically, phonologically, or semantically similar words stored in the mental lexicon. We report five experiments with Dutch speakers that show that reading an inflectional word form in its linguistic context is also affected by analogical sets of formally similar words. Using the self-paced reading technique, we show in Experiments 1-3 that an incorrectly spelled suffix delays readers less if the incorrect spelling is in line with the spelling of verbal suffixes in other inflectional forms of the same verb. In Experiments 4 and 5, our use of the self-paced reading technique shows that formally similar words with different stems affect the reading of incorrect suffixal allomorphs on a given stem. These intra- and interparadigmatic effects in reading may be due to online processes or to the storage of incorrect forms resulting from analogical effects in production.

Abstract

Amsterdam klinkt in informele gesprekken vaak als Amsdam en Rotterdam als Rodam, zonder dat de meeste moedertaalsprekers zich daar bewust van zijn. In alledaagse situaties valt een aanzienlijk deel van de klanken weg. Daarnaast worden veel klanken zwakker gearticuleerd (bijvoorbeeld een d als een j, als de mond niet helemaal afgesloten wordt). Het lijkt waarschijnlijk dat deze half uitgesproken woorden een probleem vormen voor tweedetaalleerders. Gereduceerde vormen kunnen immers sterk afwijken van de vormen die deze leerders geleerd hebben. Of dit werkelijk zo is, hebben de auteurs onderzocht in twee studies. Voordat ze deze twee studies bespreken, vertellen ze eerst kort iets over de verschillende typen reducties die voorkomen.