Publications

Displaying 301 - 400 of 649
  • Klein, W. (1990). Language acquisition. In M. Piattelli Palmarini (Ed.), Cognitive science in Europe: Issues and trends: Golem monograph series, 1 (pp. 65-77). Ivrea: Golem.
  • Klein, W. (1993). Learner varieties and theoretical linguistics. In C. Perdue (Ed.), Adult language acquisition: Cross-linguistic perspectives. Cambridge: Cambridge University Press.
  • Klein, W. (Ed.). (1983). Intonation [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (49).
  • Klein, W. (2013). European Science Foundation (ESF) Project. In P. Robinson (Ed.), The Routledge encyclopedia of second language acquisition (pp. 220-221). New York: Routledge.
  • Klein, W. (1992). Tempus, Aspekt und Zeitadverbien. Kognitionswissenschaft, 2, 107-118.
  • Klein, W. (Ed.). (1992). Textlinguistik [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (86).
  • Klein, W., & Von Stutterheim, C. (1992). Textstruktur und referentielle Bewegung. Zeitschrift für Literaturwissenschaft und Linguistik, 86, 67-92.
  • Klein, W., & Carroll, M. (1992). The acquisition of German. In W. Klein, & C. Perdue (Eds.), Utterance structure: Developing grammars again (pp. 123-188). Amsterdam: Benjamins.
  • Klein, W. (1993). Some notorious pitfalls in the analysis of spatial expressions. In F. Beckman, & G. Heyer (Eds.), Theorie und Praxis des Lexikons (pp. 191-204). Berlin: de Gruyter.
  • Klein, W. (1980). Some remarks on Sanders' typology of elliptical coordinations. Linguistics, 18, 871-876.

    Abstract

    Starting with Ross (1970), various proposals have been made to classify elliptical coordinations and to characterize different languages according to the types of ellipses which they admit. Sanders (1977) discusses four of these proposals, shows that they are inadequate on various grounds and proposes a fifth typology whose central claim is 'evidently correct', as he states (p. 258). In the following, I shall briefly outline this typology and then show that it is inadequate, too. Since there is only one language 1 know — German — I will take all my examples from this language. Moreover, all examples will be straightforward and easy to be judged.
  • Klein, W. (Ed.). (1990). Sprache und Raum [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (78).
  • Klein, W. (1990). Sprachverfall. In Ruprecht-Karls-Universität Heidelberg (Ed.), Sprache: Vorträge im Sommersemester (pp. 101-114). Heidelberg: Ruprecht-Karls-Universität.
  • Klein, W. (1992). The present perfect puzzle. Language, 68, 525-552.

    Abstract

    In John has left London, it is clear that the event in question, John's leaving London, has occurred in the past, for example yesterday at ten. Why is it impossible, then, to make this the event time more explicit by such an adverbial, as in Yesterday at ten, John has left London? Any solution of this puzzle crucially hinges on the meaning assigned to the perfect, and the present perfect in particular. Two such solutions, a scope solution and the 'current relevance'-solution, are discussed and shown to be inadequate. A new, strictly compositional analysis of the English perfect is suggested, and it is argued that the imcompatibility of the present perfect and most past tense adverbials has neither syntactic nor semantic reasons but follows from a simple pragmatical constraint, called here the 'position-definiteness constraint'. It is the very same constraint, which also makes an utterance such as At ten, John had left at nine pragmatically odd, even if John indeed had left at nine, and hence the utterance is true.
  • Klein, W. (1980). Vorwort. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 10, 7-8.
  • Klein, W. (1993). Wie ist der Stand der germanistischen Sprachwissenschaft, und was können wir tun, um ihn zu verbessern? Zeitschrift für Literaturwissenschaft und Linguistik, 90/91, 40-52.
  • Klein, W., & Schlieben-Lange, B. (Eds.). (1990). Zukunft der Sprache [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (79).
  • Klein, W. (1990). Überall und nirgendwo: Subjektive und objektive Momente in der Raumreferenz. Zeitschrift für Literaturwissenschaft und Linguistik, 78, 9-42.
  • Klein, W., & Perdue, C. (1993). Utterance structure. In C. Perdue (Ed.), Adult language acquisition: Cross-linguistic perspectives: Vol. 2 The results (pp. 3-40). Cambridge: Cambridge University Press.
  • Klein, W., & Perdue, C. (1992). Utterance structure: Developing grammars again. Amsterdam: Benjamins.
  • Klein, W. (1974). Variation in der Sprache. Kronberg/Ts: Scriptor.
  • Klein, W. (1974). Variation, Norm und Abweichung in der Sprache. In G. Lotzmann (Ed.), Sprach- und Sprechnormen - Verhalten und Abweichung (pp. 7-21). Heidelberg: Groos.
  • Klein, W. (1980). Verbal planning in route directions. In H. Dechert, & M. Raupach (Eds.), Temporal variables in speech (pp. 159-168). Den Haag: Mouton.
  • Klein, W. (1983). Vom Glück des Mißverstehens und der Trostlosigkeit der idealen Kommunikationsgemeinschaft. Zeitschrift für Literaturwissenschaft und Linguistik, 50, 128-140.
  • Klein, W. (2013). Von Reichtum und Armut des deutschen Wortschatzes. In Deutsche Akademie für Sprache und Dichtung, & Union der deutschen Akademien der Wissenschaften (Eds.), Reichtum und Armut der deutschen Sprache (pp. 15-55). Boston: de Gruyter.
  • Knudsen, B., & Liszkowski, U. (2013). One-year-olds warn others about negative action outcomes. Journal of Cognition and Development, 14, 424-436. doi:10.1080/15248372.2012.689387.

    Abstract

    Warning others about unexpected negative action outcomes is a paradigm case of communicative helping and prospective action understanding. The current study addressed the ontogeny of warning in infants’ gestural communication. We found that 12- and 18-month-olds (n = 84) spontaneously warned an adult by pointing out to her an aversive object hidden in her way (Problem condition). In control conditions the object was either positive (No Problem condition) or the adult had witnessed its’ placing (Problem known condition), which resulted in significantly less pointing. Results show that infants intervene spontaneously and with foresight through communication, in order to help others avoid a problem before it has occurred. These acts of warning entail an understanding of others’ negatively defined goals (to avoid an outcome) and their incorrect representations of reality. Findings support theories of altruism and social-pragmatic competencies in infancy.

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  • Kominsky, J. F., & Casasanto, D. (2013). Specific to whose body? Perspective taking and the spatial mapping of valence. Frontiers in Psychology, 4: 266. doi:10.3389/fpsyg.2013.00266.

    Abstract

    People tend to associate the abstract concepts of “good” and “bad” with their fluent and disfluent sides of space, as determined by their natural handedness or by experimental manipulation (Casasanto, 2011). Here we investigated influences of spatial perspective taking on the spatialization of “good” and “bad.” In the first experiment, participants indicated where a schematically drawn cartoon character would locate “good” and “bad” stimuli. Right-handers tended to assign “good” to the right and “bad” to the left side of egocentric space when the character shared their spatial perspective, but when the character was rotated 180° this spatial mapping was reversed: good was assigned to the character’s right side, not the participant’s. The tendency to spatialize valence from the character’s perspective was stronger in the second experiment, when participants were shown a full-featured photograph of the character. In a third experiment, most participants not only spatialized “good” and “bad” from the character’s perspective, they also based their judgments on a salient attribute of the character’s body (an injured hand) rather than their own body. Taking another’s spatial perspective encourages people to compute space-valence mappings using an allocentric frame of reference, based on the fluency with which the other person could perform motor actions with their right or left hand. When people reason from their own spatial perspective, their judgments depend, in part, on the specifics of their bodies; when people reason from someone else’s perspective, their judgments may depend on the specifics of the other person’s body, instead. - See more at: http://journal.frontiersin.org/Journal/10.3389/fpsyg.2013.00266
  • Kooijman, V., Junge, C., Johnson, E. K., Hagoort, P., & Cutler, A. (2013). Predictive brain signals of linguistic development. Frontiers in Psychology, 4: 25. doi:10.3389/fpsyg.2013.00025.

    Abstract

    The ability to extract word forms from continuous speech is a prerequisite for constructing a vocabulary and emerges in the first year of life. Electrophysiological (ERP) studies of speech segmentation by 9- to 12-month-old listeners in several languages have found a left-localized negativity linked to word onset as a marker of word detection. We report an ERP study showing significant evidence of speech segmentation in Dutch-learning 7-month-olds. In contrast to the left-localized negative effect reported with older infants, the observed overall mean effect had a positive polarity. Inspection of individual results revealed two participant sub-groups: a majority showing a positive-going response, and a minority showing the left negativity observed in older age groups. We retested participants at age three, on vocabulary comprehension and word and sentence production. On every test, children who at 7 months had shown the negativity associated with segmentation of words from speech outperformed those who had produced positive-going brain responses to the same input. The earlier that infants show the left-localized brain responses typically indicating detection of words in speech, the better their early childhood language skills.
  • Kristensen, L. B., Wang, L., Petersson, K. M., & Hagoort, P. (2013). The interface between language and attention: Prosodic focus marking recruits a general attention network in spoken language comprehension. Cerebral Cortex, 23, 1836-1848. doi:10.1093/cercor/bhs164.

    Abstract

    In spoken language, pitch accent can mark certain information as focus, whereby more attentional resources are allocated to the focused information. Using functional magnetic resonance imaging, this study examined whether pitch accent, used for marking focus, recruited general attention networks during sentence comprehension. In a language task, we independently manipulated the prosody and semantic/pragmatic congruence of sentences. We found that semantic/pragmatic processing affected bilateral inferior and middle frontal gyrus. The prosody manipulation showed bilateral involvement of the superior/inferior parietal cortex, superior and middle temporal cortex, as well as inferior, middle, and posterior parts of the frontal cortex. We compared these regions with attention networks localized in an auditory spatial attention task. Both tasks activated bilateral superior/inferior parietal cortex, superior temporal cortex, and left precentral cortex. Furthermore, an interaction between prosody and congruence was observed in bilateral inferior parietal regions: for incongruent sentences, but not for congruent ones, there was a larger activation if the incongruent word carried a pitch accent, than if it did not. The common activations between the language task and the spatial attention task demonstrate that pitch accent activates a domain general attention network, which is sensitive to semantic/pragmatic aspects of language. Therefore, attention and language comprehension are highly interactive.

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  • Kristoffersen, J. H., Troelsgard, T., & Zwitserlood, I. (2013). Issues in sign language lexicography. In H. Jackson (Ed.), The Bloomsbury companion to lexicography (pp. 259-283). London: Bloomsbury.
  • Kupisch, T., Akpinar, D., & Stoehr, A. (2013). Gender assignment and gender agreement in adult bilinguals and second learners of French. Linguistic Approaches to Bilingualism, 3, 150-179. doi:10.1075/lab.3.2.02kup.
  • Ladd, D. R., & Dediu, D. (2013). Genes and linguistic tone. In H. Pashler (Ed.), Encyclopedia of the mind (pp. 372-373). London: Sage Publications.

    Abstract

    It is usually assumed that the language spoken by a human community is independent of the community's genetic makeup, an assumption supported by an overwhelming amount of evidence. However, the possibility that language is influenced by its speakers' genes cannot be ruled out a priori, and a recently discovered correlation between the geographic distribution of tone languages and two human genes seems to point to a genetically influenced bias affecting language. This entry describes this specific correlation and highlights its major implications. Voice pitch has a variety of communicative functions. Some of these are probably universal, such as conveying information about the speaker's sex, age, and emotional state. In many languages, including the European languages, voice pitch also conveys certain sentence-level meanings such as signaling that an utterance is a question or an exclamation; these uses of pitch are known as intonation. Some languages, however, known as tone languages, nian ...
  • Ladd, D. R., & Cutler, A. (1983). Models and measurements in the study of prosody. In A. Cutler, & D. R. Ladd (Eds.), Prosody: Models and measurements (pp. 1-10). Heidelberg: Springer.
  • Ladd, D. R., Turnbull, R., Browne, C., Caldwell-Harris, C., Ganushchak, L. Y., Swoboda, K., Woodfield, V., & Dediu, D. (2013). Patterns of individual differences in the perception of missing-fundamental tones. Journal of Experimental Psychology: Human Perception and Performance, 39(5), 1386-1397. doi:10.1037/a0031261.

    Abstract

    Recent experimental findings suggest stable individual differences in the perception of auditory stimuli lacking energy at the fundamental frequency (F0), here called missing fundamental (MF) tones. Specifically, some individuals readily identify the pitch of such tones with the missing F0 ("F0 listeners"), and some base their judgment on the frequency of the partials that make up the tones ("spectral listeners"). However, the diversity of goals and methods in recent research makes it difficult to draw clear conclusions about individual differences. The first purpose of this article is to discuss the influence of methodological choices on listeners' responses. The second goal is to report findings on individual differences in our own studies of the MF phenomenon. In several experiments, participants judged the direction of pitch change in stimuli composed of two MF tones, constructed so as to reveal whether the pitch percept was based on the MF or the partials. The reported difference between F0 listeners and spectral listeners was replicated, but other stable patterns of responses were also observed. Test-retest reliability is high. We conclude that there are genuine, stable individual differences underlying the diverse findings, but also that there are more than two general types of listeners, and that stimulus variables strongly affect some listeners' responses. This suggests that it is generally misleading to classify individuals as "F0 listeners" or "spectral listeners." It may be more accurate to speak of two modes of perception ("F0 listening" and "spectral listening"), both of which are available to many listeners. The individual differences lie in what conditions the choice between the two modes.
  • Lai, V. T., & Curran, T. (2013). ERP evidence for conceptual mappings and comparison processes during the comprehension of conventional and novel metaphors. Brain and Language, 127(3), 484-496. doi:10.1016/j.bandl.2013.09.010.

    Abstract

    Cognitive linguists suggest that understanding metaphors requires activation of conceptual mappings between the involved concepts. We tested whether mappings are indeed in use during metaphor comprehension, and what mapping means as a cognitive process with Event-Related Potentials. Participants read literal, conventional metaphorical, novel metaphorical, and anomalous target sentences preceded by primes with related or unrelated mappings. Experiment 1 used sentence-primes to activate related mappings, and Experiment 2 used simile-primes to induce comparison thinking. In the unprimed conditions of both experiments, metaphors elicited N400s more negative than the literals. In Experiment 1, related sentence-primes reduced the metaphor-literal N400 difference in conventional, but not in novel metaphors. In Experiment 2, related simile-primes reduced the metaphor-literal N400 difference in novel, but not clearly in conventional metaphors. We suggest that mapping as a process occurs in metaphors, and the ways in which it can be facilitated by comparison differ between conventional and novel metaphors.

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  • Lai, J., & Poletiek, F. H. (2013). How “small” is “starting small” for learning hierarchical centre-embedded structures? Journal of Cognitive Psychology, 25, 423-435. doi:10.1080/20445911.2013.779247.

    Abstract

    Hierarchical centre-embedded structures pose a large difficulty for language learners due to their complexity. A recent artificial grammar learning study (Lai & Poletiek, 2011) demonstrated a starting-small (SS) effect, i.e., staged-input and sufficient exposure to 0-level-of-embedding exemplars were the critical conditions in learning AnBn structures. The current study aims to test: (1) a more sophisticated type of SS (a gradually rather than discretely growing input), and (2) the frequency distribution of the input. The results indicate that SS optimally works under other conditional cues, such as a skewed frequency distribution with simple stimuli being more numerous than complex ones.
  • Lai, V. T., & Boroditsky, L. (2013). The immediate and chronic influence of spatio-temporal metaphors on the mental representations of time in English, Mandarin, and Mandarin-English speakers. Frontiers in Psychology, 4: 142. doi:10.3389/fpsyg.2013.00142.

    Abstract

    In this paper we examine whether experience with spatial metaphors for time has an influence on people’s representation of time. In particular we ask whether spatiotemporal metaphors can have both chronic and immediate effects on temporal thinking. In Study 1, we examine the prevalence of ego-moving representations for time in Mandarin speakers, English speakers, and Mandarin-English (ME) bilinguals. As predicted by observations in linguistic analyses, we find that Mandarin speakers are less likely to take an ego-moving perspective than are English speakers. Further, we find that ME bilinguals tested in English are less likely to take an ego-moving perspective than are English monolinguals (an effect of L1 on meaning-making in L2), and also that ME bilinguals tested in Mandarin are more likely to take an ego-moving perspective than are Mandarin monolinguals (an effect of L2 on meaning-making in L1). These findings demonstrate that habits of metaphor use in one language can influence temporal reasoning in another language, suggesting the metaphors can have a chronic effect on patterns in thought. In Study 2 we test Mandarin speakers using either horizontal or vertical metaphors in the immediate context of the task. We find that Mandarin speakers are more likely to construct front-back representations of time when understanding front-back metaphors, and more likely to construct up-down representations of time when understanding up-down metaphors. These findings demonstrate that spatiotemporal metaphors can also have an immediate influence on temporal reasoning. Taken together, these findings demonstrate that the metaphors we use to talk about time have both immediate and long-term consequences for how we conceptualize and reason about this fundamental domain of experience.
  • Larson-Prior, L., Oostenveld, R., Della Penna, S., Michalareas, G., Prior, F., Babajani-Feremi, A., Schoffelen, J.-M., Marzetti, L., de Pasquale, F., Pompeo, F. D., Stout, J., Woolrich, M., Luo, Q., Bucholz, R., Fries, P., Pizzella, V., Romani, G., Corbetta, M., & Snyder, A. (2013). Adding dynamics to the Human Connectome Project with MEG. NeuroImage, 80, 190-201. doi:10.1016/j.neuroimage.2013.05.056.

    Abstract

    The Human Connectome Project (HCP) seeks to map the structural and functional connections between network elements in the human brain. Magnetoencephalography (MEG) provides a temporally rich source of information on brain network dynamics and represents one source of functional connectivity data to be provided by the HCP. High quality MEG data will be collected from 50 twin pairs both in the resting state and during performance of motor, working memory and language tasks. These data will be available to the general community. Additionally, using the cortical parcellation scheme common to all imaging modalities, the HCP will provide processing pipelines for calculating connection matrices as a function of time and frequency. Together with structural and functional data generated using magnetic resonance imaging methods, these data represent a unique opportunity to investigate brain network connectivity in a large cohort of normal adult human subjects. The analysis pipeline software and the dynamic connectivity matrices that it generates will all be made freely available to the research community.
  • Lausberg, H., & Sloetjes, H. (2013). NEUROGES in combination with the annotation tool ELAN. In H. Lausberg (Ed.), Understanding body movement: A guide to empirical research on nonverbal behaviour with an introduction to the NEUROGES coding system (pp. 199-200). Frankfurt a/M: Lang.
  • Leedham, S. J., Rodenas-Cuadrado, P., Howarth, K., Lewis, A., Mallappa, S., Segditsas, S., Davis, H., Jeffery, R., Rodriguez-Justo, M., Keshav, S., Travis, S. P. L., Graham, T. A., East, J., Clark, S., & Tomlinson, I. P. M. (2013). A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts. Gut, 62(1), 83-93. doi:10.1136/gutjnl-2011-301601.

    Abstract

    Objective Wnt signalling is critical for normal intestinal development and homeostasis. Wnt dysregulation occurs in almost all human and murine intestinal tumours and an optimal but not excessive level of Wnt activation is considered favourable for tumourigenesis. The authors assessed effects of pan-intestinal Wnt activation on tissue homeostasis, taking into account underlying physiological Wnt activity and stem-cell number in each region of the bowel. Design The authors generated mice that expressed temporally controlled, stabilised β-catenin along the crypt–villus axis throughout the intestines. Physiological Wnt target gene activity was assessed in different regions of normal mouse and human tissue. Human intestinal tumour mutation spectra were analysed. Results In the mouse, β-catenin stabilisation resulted in a graduated neoplastic response, ranging from dysplastic transformation of the entire epithelium in the proximal small bowel to slightly enlarged crypts of non-dysplastic morphology in the colorectum. In contrast, stem and proliferating cell numbers were increased in all intestinal regions. In the normal mouse and human intestines, stem-cell and Wnt gradients were non-identical, but higher in the small bowel than large bowel in both species. There was also variation in the expression of some Wnt modulators. Human tumour analysis confirmed that different APC mutation spectra are selected in different regions of the bowel. Conclusions There are variable gradients in stem-cell number, physiological Wnt activity and response to pathologically increased Wnt signalling along the crypt-villus axis and throughout the length of the intestinal tract. The authors propose that this variation influences regional mutation spectra, tumour susceptibility and lesion distribution in mice and humans.
  • Lenkiewicz, A., & Drude, S. (2013). Automatic annotation of linguistic 2D and Kinect recordings with the Media Query Language for Elan. In Proceedings of Digital Humanities 2013 (pp. 276-278).

    Abstract

    Research in body language with use of gesture recognition and speech analysis has gained much attention in the recent times, influencing disciplines related to image and speech processing.

    This study aims to design the Media Query Language (MQL) (Lenkiewicz, et al. 2012) combined with the Linguistic Media Query Interface (LMQI) for Elan (Wittenburg, et al. 2006). The system integrated with the new achievements in audio-video recognition will allow querying media files with predefined gesture phases (or motion primitives) and speech characteristics as well as combinations of both. For the purpose of this work the predefined motions and speech characteristics are called patterns for atomic elements and actions for a sequence of patterns. The main assumption is that a user-customized library of patterns and actions and automated media annotation with LMQI will reduce annotation time, hence decreasing costs of creation of annotated corpora. Increase of the number of annotated data should influence the speed and number of possible research in disciplines in which human multimodal interaction is a subject of interest and where annotated corpora are required.
  • Lenkiewicz, P., Pereira, M., Freire, M. M., & Fernandes, J. (2013). The whole mesh deformation model: A fast image segmentation method suitable for effective parallelization. EURASIP Journal on Advances in Signal Processing, 2013: 55. doi:10.1186/1687-6180-2013-55.

    Abstract

    In this article, we propose a novel image segmentation method called the whole mesh deformation (WMD) model, which aims at addressing the problems of modern medical imaging. Such problems have raised from the combination of several factors: (1) significant growth of medical image volumes sizes due to increasing capabilities of medical acquisition devices; (2) the will to increase the complexity of image processing algorithms in order to explore new functionality; (3) change in processor development and turn towards multi processing units instead of growing bus speeds and the number of operations per second of a single processing unit. Our solution is based on the concept of deformable models and is characterized by a very effective and precise segmentation capability. The proposed WMD model uses a volumetric mesh instead of a contour or a surface to represent the segmented shapes of interest, which allows exploiting more information in the image and obtaining results in shorter times, independently of image contents. The model also offers a good ability for topology changes and allows effective parallelization of workflow, which makes it a very good choice for large datasets. We present a precise model description, followed by experiments on artificial images and real medical data.
  • De León, L., & Levinson, S. C. (Eds.). (1992). Space in Mesoamerican languages [Special Issue]. Zeitschrift für Phonetik, Sprachwissenschaft und Kommunikationsforschung, 45(6).
  • Lev-Ari, S., & Peperkamp, S. (2013). Low inhibitory skill leads to non-native perception and production in bilinguals’ native language. Journal of Phonetics, 41(5), 320-331. doi:10.1016/j.wocn.2013.06.002.

    Abstract

    Learning a second language influences speakers’ first language, but there is great variability in the degree of influence that speakers exhibit. We show that some of this variability is due to individual differences in inhibitory skill. Particularly, we propose that poorer inhibitory skill leads to greater activation of competing items from the language not in use, and that this greater co-activation ultimately leads to greater influence of the co-activated items on one another. Specifically, we show that bilinguals with lower inhibitory skill exhibit greater influence of the second language on the first. Late English–French bilinguals residing in France produced and perceived Voice Onset Time of voiceless stops in English in a more French-like manner, the lower their inhibitory skill was. We discuss the implications of these results for the role of inhibitory skill in shaping representation in bilingual as well as monolingual language processing.
  • Levelt, W. J. M. (1993). Die konnektionistische Mode. In J. Engelkamp, & T. Pechmann (Eds.), Mentale Repräsentation (pp. 51-62). Bern: Huber Verlag.
  • Levelt, W. J. M. (2013). A history of psycholinguistics: The pre-Chomskyan era. Oxford: Oxford University Press.

    Abstract

    Describes the history of the field in terms of its multidisciplinary "roots" so that readers from different disciplines can concentrate on, or selectively read, the corresponding chapters. * Explores the history of research on brain and language, making the book valuable for aphasiologists, communication scientists and neuroscientists of language. * Covers the history of linguistic approaches to psycholinguistics - making the book of interest to both theoretical and applied linguists. * Written by a scientist whose own contribution to the field has been seminal, resulting in a work that will be seen as the definitive of psycholinguistics, for many years to come How do we manage to speak and understand language? How do children acquire these skills and how does the brain support them?These psycholinguistic issues have been studied for more than two centuries. Though many Psycholinguists tend to consider their history as beginning with the Chomskyan "cognitive revolution" of the late 1950s/1960s, the history of empirical psycholinguistics actually goes back to the end of the 18th century. This is the first book to comprehensively treat this "pre-Chomskyan" history. It tells the fascinating history of the doctors, pedagogues, linguists and psychologists who created this discipline, looking at how they made their important discoveries about the language regions in the brain, about the high-speed accessing of words in speaking and listening, on the child's invention of syntax, on the disruption of language in aphasic patients and so much more. The book is both a history of ideas as well of the men and women whose intelligence, brilliant insights, fads, fallacies, cooperations, and rivalries created this discipline. Psycholinguistics has four historical roots, which, by the end of the 19th century, had merged. By then, the discipline, usually called the psychology of language, was established. The first root was comparative linguistics, which raised the issue of the psychological origins of language. The second root was the study of language in the brain, with Franz Gall as the pioneer and the Broca and Wernicke discoveries as major landmarks. The third root was the diary approach to child development, which emerged from Rousseau's Émile. The fourth root was the experimental laboratory approach to speech and language processing, which originated from Franciscus Donders' mental chronometry. Wilhelm Wundt unified these four approaches in his monumental Die Sprache of 1900. These four perspectives of psycholinguistics continued into the 20th century but in quite divergent frameworks. There was German consciousness and thought psychology, Swiss/French and Prague/Viennese structuralism, Russian and American behaviorism, and almost aggressive holism in aphasiology. As well as reviewing all these perspectives, the book looks at the deep disruption of the field during the Third Reich and its optimistic, multidisciplinary re-emergence during the 1950s with the mathematical theory of communication as a major impetus. A tour de force from one of the seminal figures in the field, this book will be essential reading for all linguists, psycholinguists, and psychologists with an interest in language. Readership: Linguists, psychologists, aphasiologists, communication scientists, cognitive (neuro-)scientists, whether professionals or graduate students. Historians of science
  • Levelt, W. J. M. (1993). Accessing words in speech production: Stages, processes and representations. In W. J. M. Levelt (Ed.), Lexical access in speech production (pp. 1-22). Cambridge, MA: Blackwell Publishers.

    Abstract

    Originally published in Cognition International Journal of Cognitive Science, Volume 42, Numbers 1-3, 1992 This paper introduces a special issue of Cognition 011 lexical access in speech production. Over the last quarter century, the psycholinguistic study of speaking, and in particular of accessing words in speech, received a major new impetus from the analysis of speech errors, dysfluencies and hesMions, from aphasiology, and from new paradigms in reaction time research. The emerging theoretical picture partitions the accessing process into two subprocesses, the selection of an appropriate lexical item (and "lemma") from the mental lexicon, and the phonological encoding of that item, that is, the computation of a phonetic program for the item in the context of utterance These two theoretical domains are successively introduced by outlining some core issues that have been or still have to be addressed. The final section discusses the controversial question whether phonological encoding can affect lexical selection. This partitioning is also followed in this special issue as a whole. There are, first, four papers on lexical selection, then three papers on phonological encoding, and finally one on the interaction between selection and phonological encoding.
  • Levelt, W. J. M. (1992). Accessing words in speech production: Stages, processes and representations. Cognition, 42, 1-22. doi:10.1016/0010-0277(92)90038-J.

    Abstract

    This paper introduces a special issue of Cognition on lexical access in speech production. Over the last quarter century, the psycholinguistic study of speaking, and in particular of accessing words in speech, received a major new impetus from the analysis of speech errors, dysfluencies and hesitations, from aphasiology, and from new paradigms in reaction time research. The emerging theoretical picture partitions the accessing process into two subprocesses, the selection of an appropriate lexical item (a “lemma”) from the mental lexicon, and the phonological encoding of that item, that is, the computation of a phonetic program for the item in the context of utterance. These two theoretical domains are successively introduced by outlining some core issues that have been or still have to be addressed. The final section discusses the controversial question whether phonological encoding can affect lexical selection. This partitioning is also followed in this special issue as a whole. There are, first, four papers on lexical selection, then three papers on phonological encoding, and finally one on the interaction between selection and phonological encoding.
  • Levelt, W. J. M. (1990). De connectionistische mode. In P. Van Hoogstraten (Ed.), Belofte en werkelijkheid: Sociale wetenschappen en informatisering (pp. 39-68). Lisse: Swets & Zeitlinger.
  • Levelt, W. J. M. (1990). Are multilayer feedforward networks effectively turing machines? Psychological Research, 52, 153-157.
  • Levelt, W. J. M. (1992). Fairness in reviewing: A reply to O'Connell. Journal of Psycholinguistic Research, 21, 401-403.
  • Levelt, W. J. M. (1974). Formal grammars in linguistics and psycholinguistics: Vol.III, Psycholinguistic applications. The Hague: Mouton.
  • Levelt, W. J. M. (1974). Formal grammars in linguistics and psycholinguistics: Vol. I, An introduction to the theory of formal languages and automata. The Hague: Mouton Publishers.
  • Levelt, W. J. M. (1974). Formal grammars in linguistics and psycholinguistics: Vol.II, Applications in linguistic theory. The Hague: Mouton.
  • Levelt, W. J. M. (1983). Monitoring and self-repair in speech. Cognition, 14, 41-104. doi:10.1016/0010-0277(83)90026-4.

    Abstract

    Making a self-repair in speech typically proceeds in three phases. The first phase involves the monitoring of one’s own speech and the interruption of the flow of speech when trouble is detected. From an analysis of 959 spontaneous self-repairs it appears that interrupting follows detection promptly, with the exception that correct words tend to be completed. Another finding is that detection of trouble improves towards the end of constituents. The second phase is characterized by hesitation, pausing, but especially the use of so-called editing terms. Which editing term is used depends on the nature of the speech trouble in a rather regular fashion: Speech errors induce other editing terms than words that are merely inappropriate, and trouble which is detected quickly by the speaker is preferably signalled by the use of ‘uh’. The third phase consists of making the repair proper The linguistic well-formedness of a repair is not dependent on the speaker’s respecting the integriv of constituents, but on the structural relation between original utterance and repair. A bi-conditional well-formedness rule links this relation to a corresponding relation between the conjuncts of a coordination. It is suggested that a similar relation holds also between question and answer. In all three cases the speaker respects certain Istructural commitments derived from an original utterance. It was finally shown that the editing term plus the first word of the repair proper almost always contain sufficient information for the listener to decide how the repair should be related to the original utterance. Speakers almost never produce misleading information in this respect. It is argued that speakers have little or no access to their speech production process; self-monitoring is probably based on parsing one’s own inner or overt speech.
  • Levelt, W. J. M. (1962). Motion breaking and the perception of causality. In A. Michotte (Ed.), Causalité, permanence et réalité phénoménales: Etudes de psychologie expérimentale (pp. 244-258). Louvain: Publications Universitaires.
  • Levelt, W. J. M., & Plomp, R. (1962). Musical consonance and critical bandwidth. In Proceedings of the 4th International Congress Acoustics (pp. 55-55).
  • Levelt, W. J. M. (1993). Lexical access in speech production. In E. Reuland, & W. Abraham (Eds.), Knowledge and language: Vol. 1. From Orwell's problem to Plato's problem (pp. 241-251). Dordrecht: Kluwer.
  • Levelt, W. J. M. (Ed.). (1993). Lexical access in speech production. Cambridge, Mass.: Blackwell.

    Abstract

    Formerly published in: Cognition : international journal of cognitive science, vol. 42, nos. 1-3, 1992
  • Levelt, W. J. M. (1993). Lexical selection, or how to bridge the major rift in language processing. In F. Beckmann, & G. Heyer (Eds.), Theorie und Praxis des Lexikons (pp. 164-172). Berlin: Walter de Gruyter.
  • Levelt, W. J. M. (1974). J.B. Carroll & R. Freedle (eds.), Language comprehension and the acquisition of knowledge [Book review]. The Quarterly journal of experimental psychology, 26(2), 325-326. doi:10.1080/14640747408400419.
  • Levelt, W. J. M. (1990). On learnability, empirical foundations, and naturalness [Commentary on Hanson & Burr]. Behavioral and Brain Sciences, 13(3), 501. doi:10.1017/S0140525X00079887.
  • Levelt, W. J. M. (1980). On-line processing constraints on the properties of signed and spoken language. In U. Bellugi, & M. Studdert-Kennedy (Eds.), Signed and spoken language: Biological constraints on linguistic form (pp. 141-160). Weinheim: Verlag Chemie.

    Abstract

    It is argued that the dominantly successive nature of language is largely mode-independent and holds equally for sign and for spoken language. A preliminary distinction is made between what is simultaneous or successive in the signal, and what is in the process; these need not coincide, and it is the successiveness of the process that is at stake. It is then discussed extensively for the word/sign level, and in a more preliminary fashion for the clause and discourse level that online processes are parallel in that they can simultaneously draw on various sources of knowledge (syntactic, semantic, pragmatic), but successive in that they can work at the interpretation of only one unit at a time. This seems to hold for both sign and spoken language. In the final section, conjectures are made about possible evolutionary explanations for these properties of language processing.
  • Levelt, W. J. M., & Cutler, A. (1983). Prosodic marking in speech repair. Journal of semantics, 2, 205-217. doi:10.1093/semant/2.2.205.

    Abstract

    Spontaneous self-corrections in speech pose a communication problem; the speaker must make clear to the listener not only that the original Utterance was faulty, but where it was faulty and how the fault is to be corrected. Prosodic marking of corrections - making the prosody of the repair noticeably different from that of the original utterance - offers a resource which the speaker can exploit to provide the listener with such information. A corpus of more than 400 spontaneous speech repairs was analysed, and the prosodic characteristics compared with the syntactic and semantic characteristics of each repair. Prosodic marking showed no relationship at all with the syntactic characteristics of repairs. Instead, marking was associated with certain semantic factors: repairs were marked when the original utterance had been actually erroneous, rather than simply less appropriate than the repair; and repairs tended to be marked more often when the set of items encompassing the error and the repair was small rather than when it was large. These findings lend further weight to the characterization of accent as essentially semantic in function.
  • Levelt, W. J. M. (1992). Psycholinguistics: An overview. In W. Bright (Ed.), International encyclopedia of linguistics (Vol. 3) (pp. 290-294). Oxford: Oxford University Press.
  • Levelt, W. J. M. (1993). The architecture of normal spoken language use. In G. Blanken, J. Dittman, H. Grimm, J. C. Marshall, & C.-W. Wallesch (Eds.), Linguistic disorders and pathologies: An international handbook (pp. 1-15). Berlin: Walter de Gruyter.
  • Levelt, W. J. M. (1990). Some studies of lexical access at the Max Planck Institute for Psycholinguistics. In F. Aarts, & T. Van Els (Eds.), Contemporary Dutch linguistics (pp. 131-139). Washington: Georgetown University Press.
  • Levelt, W. J. M. (1992). Sprachliche Musterbildung und Mustererkennung. Nova Acta Leopoldina NF, 67(281), 357-370.
  • Levelt, W. J. M. (1993). Spreken als vaardigheid. In C. Blankenstijn, & A. Scheper (Eds.), Taalvaardigheid (pp. 1-16). Dordrecht: ICG Publications.
  • Levelt, W. J. M. (1974). Taalpsychologie: Van taalkunde naar psychologie. In Herstal-Conferentie.
  • Levelt, W. J. M. (1992). The perceptual loop theory not disconfirmed: A reply to MacKay. Consciousness and Cognition, 1, 226-230. doi:10.1016/1053-8100(92)90062-F.

    Abstract

    In his paper, MacKay reviews his Node Structure theory of error detection, but precedes it with a critical discussion of the Perceptual Loop theory of self-monitoring proposed in Levelt (1983, 1989). The present commentary is concerned with this latter critique and shows that there are more than casual problems with MacKay’s argumentation.
  • Levelt, W. J. M. (1983). The speaker's organization of discourse. In Proceedings of the XIIIth International Congress of Linguists (pp. 278-290).
  • Levelt, W. J. M. (1983). Wetenschapsbeleid: Drie actuele idolen en een godin. Grafiet, 1(4), 178-184.
  • Levelt, W. J. M. (1993). Timing in speech production with special reference to word form encoding. Annals of the New York Academy of Sciences, 682, 283-295. doi:10.1111/j.1749-6632.1993.tb22976.x.
  • Levelt, W. J. M. (1980). Toegepaste aspecten van het taal-psychologisch onderzoek: Enkele inleidende overwegingen. In J. Matter (Ed.), Toegepaste aspekten van de taalpsychologie (pp. 3-11). Amsterdam: VU Boekhandel.
  • Levinson, S. C. (1992). Space in Australian Languages Questionnaire. In S. C. Levinson (Ed.), Space stimuli kit 1.2 (pp. 29-40). Nijmegen: Max Planck Institute for Psycholinguistics.

    Abstract

    This questionnaire is designed to explore how spatial relations are encoded in Australian language, but may be of interest to researchers further afield.
  • Levinson, S. C. (1992). Space in Australian Languages Questionnaire. In S. C. Levinson (Ed.), Space stimuli kit 1.2 (pp. 29-40). Nijmegen: Max Planck Institute for Psycholinguistics. doi:10.17617/2.3512641.

    Abstract

    This questionnaire is designed to explore how spatial relations are encoded in Australian language, but may be of interest to researchers further afield.
  • Levinson, S. C., & Brown, P. (1993). Background to "Immanuel Kant among the Tenejapans". Anthropology Newsletter, 34(3), 22-23. doi:10.1111/an.1993.34.3.22.
  • Levinson, S. C. (2013). Action formation and ascription. In T. Stivers, & J. Sidnell (Eds.), The handbook of conversation analysis (pp. 103-130). Malden, MA: Wiley-Blackwell. doi:10.1002/9781118325001.ch6.

    Abstract

    Since the core matrix for language use is interaction, the main job of language
    is not to express propositions or abstract meanings, but to deliver actions.
    For in order to respond in interaction we have to ascribe to the prior turn
    a primary ‘action’ – variously thought of as an ‘illocution’, ‘speech act’, ‘move’,
    etc. – to which we then respond. The analysis of interaction also relies heavily
    on attributing actions to turns, so that, e.g., sequences can be characterized in
    terms of actions and responses. Yet the process of action ascription remains way
    understudied. We don’t know much about how it is done, when it is done, nor even
    what kind of inventory of possible actions might exist, or the degree to which they
    are culturally variable.
    The study of action ascription remains perhaps the primary unfulfilled task in
    the study of language use, and it needs to be tackled from conversationanalytic,
    psycholinguistic, cross-linguistic and anthropological perspectives.
    In this talk I try to take stock of what we know, and derive a set of goals for and
    constraints on an adequate theory. Such a theory is likely to employ, I will suggest,
    a top-down plus bottom-up account of action perception, and a multi-level notion
    of action which may resolve some of the puzzles that have repeatedly arisen.
  • Levinson, S. C. (1992). Activity types and language. In P. Drew, & J. Heritage (Eds.), Talk at work: Interaction in institutional settings (pp. 66-100). Cambridge University Press.
  • Levinson, S. C. (2013). Cross-cultural universals and communication structures. In M. A. Arbib (Ed.), Language, music, and the brain: A mysterious relationship (pp. 67-80). Cambridge, MA: MIT Press.

    Abstract

    Given the diversity of languages, it is unlikely that the human capacity for language resides in rich universal syntactic machinery. More likely, it resides centrally in the capacity for vocal learning combined with a distinctive ethology for communicative interaction, which together (no doubt with other capacities) make diverse languages learnable. This chapter focuses on face-to-face communication, which is characterized by the mapping of sounds and multimodal signals onto speech acts and which can be deeply recursively embedded in interaction structure, suggesting an interactive origin for complex syntax. These actions are recognized through Gricean intention recognition, which is a kind of “ mirroring” or simulation distinct from the classic mirror neuron system. The multimodality of conversational interaction makes evident the involvement of body, hand, and mouth, where the burden on these can be shifted, as in the use of speech and gesture, or hands and face in sign languages. Such shifts having taken place during the course of human evolution. All this suggests a slightly different approach to the mystery of music, whose origins should also be sought in joint action, albeit with a shift from turn-taking to simultaneous expression, and with an affective quality that may tap ancient sources residual in primate vocalization. The deep connection of language to music can best be seen in the only universal form of music, namely song.
  • Levinson, S. C., Brown, P., Danzinger, E., De León, L., Haviland, J. B., Pederson, E., & Senft, G. (1992). Man and Tree & Space Games. In S. C. Levinson (Ed.), Space stimuli kit 1.2 (pp. 7-14). Nijmegen: Max Planck Institute for Psycholinguistics. doi:10.17617/2.2458804.

    Abstract

    These classic tasks can be used to explore spatial reference in field settings. They provide a language-independent metric for eliciting spatial language, using a “director-matcher” paradigm. The Man and Tree task deals with location on the horizontal plane with both featured (man) and non-featured (e.g., tree) objects. The Space Games depict various objects (e.g. bananas, lemons) and elicit spatial contrasts not obviously lexicalisable in English.
  • Levinson, S. C. (1993). La Pragmatica [Italian translation of Pragmatics]. Bologna: Il Mulino.
  • Levinson, S. C. (1992). Primer for the field investigation of spatial description and conception. Pragmatics, 2(1), 5-47.
  • Levinson, S. C. (1993). Raumkonzeptionen mit absoluten Systemen. In Max Planck Gesellschaft Jahrbuch 1993 (pp. 297-299).
  • Levinson, S. C. (2013). Recursion in pragmatics. Language, 89, 149-162. doi:10.1353/lan.2013.0005.

    Abstract

    There has been a recent spate of work on recursion as a central design feature of language. This short report points out that there is little evidence that unlimited recursion, understood as center-embedding, is typical of natural language syntax. Nevertheless, embedded pragmatic construals seem available in every language. Further, much deeper center-embedding can be found in dialogue or conversation structure than can be found in syntax. Existing accounts for the 'performance' limitations on center-embedding are thus thrown into doubt. Dialogue materials suggest that center-embedding is perhaps a core part of the human interaction system, and is for some reason much more highly restricted in syntax than in other aspects of cognition.
  • Levinson, S. C. (1980). Speech act theory: The state of the art. Language teaching and linguistics: Abstracts, 5-24.

    Abstract

    Survey article
  • Levinson, S. C. (1983). Pragmatics. Cambridge: Cambridge University Press.
  • Levinson, S. C. (1990). Pragmatics [Japanese translation]. Tokyo: Kenkyusha.
  • Levinson, S. C. (1990). Pragmatik [German translation of Pragmatics]. Tübingen: Niemeyer.

    Abstract

    This is the German translation of Stephen C. Levinson's »Pragmatics«.
  • Levinson, S. C., & Dediu, D. (2013). The interplay of genetic and cultural factors in ongoing language evolution. In P. J. Richerson, & M. H. Christiansen (Eds.), Cultural evolution: Society, technology, language, and religion. Strüngmann Forum Reports, vol. 12 (pp. 219-232). Cambridge, Mass: MIT Press.
  • Levinson, S. C., & Majid, A. (2013). The island of time: Yélî Dnye, the language of Rossel Island. Frontiers in Psychology, 4: 61. doi:10.3389/fpsyg.2013.00061.

    Abstract

    This paper describes the linguistic description of time, the accompanying gestural system, and the “mental time lines” found in the speakers of Yélî Dnye, an isolate language spoken offshore from Papua New Guinea. Like many indigenous languages, Yélî Dnye has no fixed anchoring of time and thus no calendrical time. Instead, time in Yélî Dnye linguistic
    description is primarily anchored to the time of speaking, with six diurnal tenses and special nominals for n days from coding time; this is supplemented with special constructions for overlapping events. Consequently there is relatively little cross-over or metaphor from space to time. The gesture system, on the other hand, uses pointing to sun position to indicate time of day and may make use of systematic time lines. Experimental evidence fails to show a single robust axis used for mapping time to space. This suggests that there may not be a strong, universal tendency for systematic space-time mappings.
  • Levinson, S. C., & Annamalai, E. (1992). Why presuppositions aren't conventional. In R. N. Srivastava (Ed.), Language and text: Studies in honour of Ashok R. Kelkar (pp. 227-242). Dehli: Kalinga Publications.
  • Levshina, N., Geeraerts, D., & Speelman, D. (2013). Mapping constructional spaces: A contrastive analysis of English and Dutch analytic causatives. Linguistics, 51(4), 825-854. doi:10.1515/ling-2013-0028.

    Abstract

    The paper demonstrates how verb and noun classes can be used as a common interface in contrastive Construction Grammar. It presents an innovative approach to the contrastive analysis of constructional spaces (sets of constructions covering a certain semantic domain). We compare English and Dutch analytic causatives by using the statistical technique of multiple correspondence analysis applied to data from large monolingual corpora. The method allows us to explore the common conceptual space of the constructions, in particular the salient semantic dimensions and causation types, which emerge on the basis of co-occurring semantic classes of the nominal and verbal slot fillers in constructional exemplars. The formal patterns of the constructions at different levels of specificity are projected onto this space. Our analyses show that an average Dutch analytic causative refers to more indirect and abstract causation with fewer animate than its English counterpart. We have also found that the languages “cut” the common conceptual space in unique ways, although the semantic areas of many English and Dutch constructions overlap substantially. Nevertheless, the form-meaning mapping in the two languages displays commonalities. Both English and Dutch constructions with prepositionally marked or implicit causees are strongly associated with animate causees. We have also observed a correlation between the directness of causation and the crosslinguistic hierarchy of affectedness marking proposed by Kemmer and Verhagen (1994).
  • Levshina, N., Geeraerts, D., & Speelman, D. (2013). Towards a 3D-grammar: Interaction of linguistic and extralinguistic factors in the use of Dutch causative constructions. Journal of Pragmatics, 52, 34-48. doi:10.1016/j.pragma.2012.12.013.

    Abstract

    The integration of three main dimensions of linguistic usage and variation – formal, social and conceptual – can be seen as a major ambition of the Cognitive Sociolinguistics enterprise. The paper illustrates this theoretical approach with a corpus-based study of near-synonymous causative constructions with doen and laten in the Belgian and Netherlandic varieties of Dutch. A series of quantitative analyses show a complex interplay of the dimensions at different levels of constructional schematicity. At the more schematic level, the results indicate that the effects of transitivity and coreferentiality on the probability of the two constructions are slightly different in the two varieties. However, incorporating the effected predicate slot fillers in a mixed-effect model reveals that these differences can be explained to a large extent by the country-specific lexical patterns. These findings suggest that the interplay of the lectal and conceptual factors in constructional variation should be studied at varying degrees of constructional schematicity.
  • Lindell, A. K., & Kidd, E. (2013). Consumers favor “right brain” training: The dangerous lure of neuromarketing. Mind, Brain and Education, 7(1), 35-39. doi:10.1111/mbe.12005.

    Abstract

    Over the past decade the neuromarketing of educational products has become increasingly common. Researchers have however expressed concern about the misapplication of neuroscience to education marketing, fearing that consumers may be deceived into investing in apparently “brain-based” products under the misapprehension that they will be more effective. This study provides the first demonstration that these fears are justified. We presented 180 participants with one of four advertisements for an identical educational program, named either “Right Brain” or “Right Start” Training; the advertisements either did, or did not, include an MRI brain image in one corner. Results demonstrated that “Right Brain” training was deemed more interesting, educationally valuable, and scientifically strong than an identical product named “Right Start” training. Advertisements including an unrelated brain image enhanced ratings of scientific rationale. These results confirm that by implying a strong scientific basis, “brain-based” product names are remarkably effective in implicitly manipulating consumer opinion.
  • Liszkowski, U. (2013). Using theory of mind. Child Development Perspectives, 7, 104-109. doi:10.1111/cdep.12025.

    Abstract

    The ability to flexibly predict others' behaviors has been ascribed to a theory of mind (ToM) system. Most research has focused on formal conceptual definitions of such a system, and the question of whom to credit with a ToM. In this article, I suggest shifting perspective from formal definitions to a usage-based approach. This approach views action within human interaction as central to the emergence and continuous development of the ability to flexibly predict others' behaviors. Addressing the current debate about whether infants have a ToM, I illustrate how infants use flexible action expectations to interact with others appropriately. I also discuss the continuous development of ToM and its natural structure from a usage-based perspective.
  • Liu, Y.-J., Ehrengruber, M. U., Negwer, M., Shao, H.-J., Cetin, A. H., & Lyon, D. C. (2013). Tracing inputs to inhibitory or excitatory neurons of mouse and cat visual cortex with a targeted rabies virus. Current Biology, 23(18), 1746-1755. doi:10.1016/j.cub.2013.07.033.

    Abstract

    Background Cortical inhibition plays a critical role in controlling and modulating cortical excitation and a more detailed understanding of the neuronal circuits contributing to each will provide more insight into their roles in complex cortical computations. Traditional neuronal tracers lack a means for easily distinguishing between circuits of inhibitory and excitatory neurons. To overcome this limitation, we developed a technique for retrogradely labeling inputs to local clusters of inhibitory or excitatory neurons, but not both, using neurotropic adeno-associated and lentiviral vectors, cell-type specific promoters and a modified rabies virus. Results Applied to primary visual cortex (V1) in mouse, the cell-type specific tracing technique labeled thousands of presynaptically connected neurons, and revealed that the dominant source of input to inhibitory and excitatory neurons is local in origin. Neurons in other visual areas are also labeled; the percentage of these inter-cortical inputs to excitatory neurons is somewhat higher (~20%) than to inhibitory neurons (<10%), suggesting that inter-cortical connections have less direct control over inhibition. The inputs to inhibitory neurons were also traced in cat V1, and when aligned with the orientation preference map, revealed for the first time that long-range inputs to inhibitory neurons are well tuned to orientation. Conclusions These novel findings for inhibitory and excitatory circuits in the visual cortex demonstrate the efficacy of our new technique and its ability to work across species, including larger-brained mammals such as the cat. This paves the way for better understanding the roles of specific cell-types in higher-order perceptual and cognitive processes.

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  • Lüttjohann, A., Schoffelen, J.-M., & Van Luijtelaar, G. (2013). Peri-ictal network dynamics of spike-wave discharges: Phase and spectral characteristics. Experimental Neurology, 239, 235-247. doi:10.1016/j.expneurol.2012.10.021.

    Abstract

    Purpose The brain is a highly interconnected neuronal assembly in which network analyses can greatly enlarge our knowledge on seizure generation. The cortico-thalamo-cortical network is the brain-network of interest in absence epilepsy. Here, network synchronization is assessed in a genetic absence model during 5 second long pre-ictal- > ictal transition periods. Method 16 male WAG/Rij rats were equipped with multiple electrodes targeting layer 4 to 6 of the somatosensory-cortex, rostral and caudal RTN, VPM, anterior-(ATN) and posterior (Po) thalamic nucleus. Local Field Potentials measured during pre-ictal- > ictal transition and during control periods were subjected to time-frequency and pairwise phase consistency analysis. Results Pre-ictally, all channels showed Spike-Wave Discharge (SWD) precursor activity (increases in spectral power), which were earliest and most pronounced in the somatosensory cortex. The caudal RTN decoupled from VPM, Po and cortical layer 4. Strong increases in synchrony were found between cortex and thalamus during SWD. Although increases between cortex and VPM were seen in SWD frequencies and its harmonics, boarder spectral increases (6-48 Hz) were seen between cortex and Po. All thalamic nuclei showed increased phase synchronization with Po but not with VPM. Conclusion Absence seizures are not sudden and unpredictable phenomena: the somatosensory cortex shows highest and earliest precursor activity. The pre-ictal decoupling of the caudal RTN might be a prerequisite of SWD generation. Po nucleus might be the primary thalamic counterpart to the somatosensory-cortex in the generation of the cortico-thalamic-cortical oscillations referred to as SWD.
  • Lynott, D., Connell, L., & Holler, J. (Eds.). (2013). The role of body and environment in cognition. Frontiers in Psychology, 4: 465. doi:10.3389/fpsyg.2013.00465.
  • Majid, A. (2013). Making semantics and pragmatics “sensory”. Journal of Pragmatics, 58, 48-51. doi:10.1016/j.pragma.2013.09.019.

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