Publications

Displaying 301 - 400 of 463
  • Obleser, J., & Eisner, F. (2009). Pre-lexical abstraction of speech in the auditory cortex. Trends in Cognitive Sciences, 13, 14-19. doi:10.1016/j.tics.2008.09.005.

    Abstract

    Speech perception requires the decoding of complex acoustic patterns. According to most cognitive models of spoken word recognition, this complexity is dealt with before lexical access via a process of abstraction from the acoustic signal to pre-lexical categories. It is currently unclear how these categories are implemented in the auditory cortex. Recent advances in animal neurophysiology and human functional imaging have made it possible to investigate the processing of speech in terms of probabilistic cortical maps rather than simple cognitive subtraction, which will enable us to relate neurometric data more directly to behavioural studies. We suggest that integration of insights from cognitive science, neurophysiology and functional imaging is necessary for furthering our understanding of pre-lexical abstraction in the cortex.

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  • O'Brien, D. P., & Bowerman, M. (1998). Martin D. S. Braine (1926–1996): Obituary. American Psychologist, 53, 563. doi:10.1037/0003-066X.53.5.563.

    Abstract

    Memorializes Martin D. S. Braine, whose research on child language acquisition and on both child and adult thinking and reasoning had a major influence on modern cognitive psychology. Addressing meaning as well as position, Braine argued that children start acquiring language by learning narrow-scope positional formulas that map components of meaning to positions in the utterance. These proposals were critical in starting discussions of the possible universality of the pivot-grammar stage and of the role of syntax, semantics,and pragmatics in children's early grammar and were pivotal to the rise of approaches in which cognitive development in language acquisition is stressed.
  • Ogasawara, N., & Warner, N. (2009). Processing missing vowels: Allophonic processing in Japanese. Language and Cognitive Processes, 24, 376 -411. doi:10.1080/01690960802084028.

    Abstract

    The acoustic realisation of a speech sound varies, often showing allophonic variation triggered by surrounding sounds. Listeners recognise words and sounds well despite such variation, and even make use of allophonic variability in processing. This study reports five experiments on processing of the reduced/unreduced allophonic alternation of Japanese high vowels. The results show that listeners use phonological knowledge of their native language during phoneme processing and word recognition. However, interactions of the phonological and acoustic effects differ in these two processes. A facilitatory phonological effect and an inhibitory acoustic effect cancel one another out in phoneme processing; while in word recognition, the facilitatory phonological effect overrides the inhibitory acoustic effect. Four potential models of the processing of allophonic variation are discussed. The results can be accommodated in two of them, but require additional assumptions or modifications to the models, and primarily support lexical specification of allophonic variability.

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  • Orfanidou, E., Adam, R., McQueen, J. M., & Morgan, G. (2009). Making sense of nonsense in British Sign Language (BSL): The contribution of different phonological parameters to sign recognition. Memory & Cognition, 37(3), 302-315. doi:10.3758/MC.37.3.302.

    Abstract

    Do all components of a sign contribute equally to its recognition? In the present study, misperceptions in the sign-spotting task (based on the word-spotting task; Cutler & Norris, 1988) were analyzed to address this question. Three groups of deaf signers of British Sign Language (BSL) with different ages of acquisition (AoA) saw BSL signs combined with nonsense signs, along with combinations of two nonsense signs. They were asked to spot real signs and report what they had spotted. We will present an analysis of false alarms to the nonsense-sign combinations—that is, misperceptions of nonsense signs as real signs (cf. van Ooijen, 1996). Participants modified the movement and handshape parameters more than the location parameter. Within this pattern, however, there were differences as a function of AoA. These results show that the theoretical distinctions between form-based parameters in sign-language models have consequences for online processing. Vowels and consonants have different roles in speech recognition; similarly, it appears that movement, handshape, and location parameters contribute differentially to sign recognition.
  • Otten, M., & Van Berkum, J. J. A. (2009). Does working memory capacity affect the ability to predict upcoming words in discourse? Brain Research, 1291, 92-101. doi:doi:10.1016/j.brainres.2009.07.042.

    Abstract

    Prior research has indicated that readers and listeners can use information in the prior discourse to rapidly predict specific upcoming words, as the text is unfolding. Here we used event-related potentials to explore whether the ability to make rapid online predictions depends on a reader's working memory capacity (WMC). Readers with low WMC were hypothesized to differ from high WMC readers either in their overall capability to make predictions (because of their lack of cognitive resources). High and low WMC participants read highly constraining stories that supported the prediction of a specific noun, mixed with coherent but essentially unpredictive ‘prime control’ control stories that contained the same content words as the predictive stories. To test whether readers were anticipating upcoming words, critical nouns were preceded by a determiner whose gender agreed or disagreed with the gender of the expected noun. In predictive stories, both high and low WMC readers displayed an early negative deflection (300–600 ms) to unexpected determiners, which was not present in prime control stories. Only the low WMC participants displayed an additional later negativity (900–1500 ms) to unexpected determiners. This pattern of results suggests that WMC does not influence the ability to anticipate upcoming words per se, but does change the way in which readers deal with information that disconfirms the generated prediction.
  • Ozyurek, A., & Trabasso, T. (1997). Evaluation during the understanding of narratives. Discourse Processes, 23(3), 305-337. Retrieved from http://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=12673020&site=ehost-live.

    Abstract

    Evaluation plays a role in the telling and understanding of narratives, in communicative interaction, emotional understanding, and in psychological well-being. This article reports a study of evaluation by describing how readers monitor the concerns of characters over the course of a narrative. The main hypothesis is that readers tract the well-being via the expression of a character's internal states. Reader evaluations were revealed in think aloud protocols obtained during reading of narrative texts, one sentence at a time. Five kinds of evaluative inferences were found: appraisals (good versus bad), preferences (like versus don't like), emotions (happy versus frustrated), goals (want versus don't want), or purposes (to attain or maintain X versus to prevent or avoid X). Readers evaluated all sentences. The mean rate of evaluation per sentence was 0.55. Positive and negative evaluations over the course of the story indicated that things initially went badly for characters, improved with the formulation and execution of goal plans, declined with goal failure, and improved as characters formulated new goals and succeeded. The kind of evaluation made depended upon the episodic category of the event and the event's temporal location in the story. Evaluations also served to explain or predict events. In making evaluations, readers stayed within the frame of the story and perspectives of the character or narrator. They also moved out of the narrative frame and addressed evaluations towards the experimenter in a communicative context.
  • Pederson, E., Danziger, E., Wilkins, D. G., Levinson, S. C., Kita, S., & Senft, G. (1998). Semantic typology and spatial conceptualization. Language, 74(3), 557-589. doi:10.2307/417793.
  • Petersson, K. M., Elfgren, C., & Ingvar, M. (1997). A dynamic role of the medial temporal lobe during retrieval of declarative memory in man. NeuroImage, 6, 1-11.

    Abstract

    Understanding the role of the medial temporal lobe (MTL) in learning and memory is an important problem in cognitive neuroscience. Memory and learning processes that depend on the function of the MTL and related diencephalic structures (e.g., the anterior and mediodorsal thalamic nuclei) are defined as declarative. We have studied the MTL activity as indicated by regional cerebral blood flow with positron emission tomography and statistical parametric mapping during recall of abstract designs in a less practiced memory state as well as in a well-practiced (well-encoded) memory state. The results showed an increased activity of the MTL bilaterally (including parahippocampal gyrus extending into hippocampus proper, as well as anterior lingual and anterior fusiform gyri) during retrieval in the less practiced memory state compared to the well-practiced memory state, indicating a dynamic role of the MTL in retrieval during the learning processes. The results also showed that the activation of the MTL decreases as the subjects learn to draw abstract designs from memory, indicating a changing role of the MTL during recall in the earlier stages of acquisition compared to the well-encoded declarative memory state.
  • Petersson, K. M. (1998). Comments on a Monte Carlo approach to the analysis of functional neuroimaging data. NeuroImage, 8, 108-112.
  • Petersson, K. M., Reis, A., Askelöf, S., Castro-Caldas, A., & Ingvar, M. (2000). Language processing modulated by literacy: A network analysis of verbal repetition in literate and illiterate subjects. Journal of Cognitive Neuroscience, 12(3), 364-382. doi:10.1162/089892900562147.
  • Petrovic, P., Petersson, K. M., Ghatan, P., Stone-Elander, S., & Ingvar, M. (2000). Pain related cerebral activation is altered by a distracting cognitive task. Pain, 85, 19-30.

    Abstract

    It has previously been suggested that the activity in sensory regions of the brain can be modulated by attentional mechanisms during parallel cognitive processing. To investigate whether such attention-related modulations are present in the processing of pain, the regional cerebral blood ¯ow was measured using [15O]butanol and positron emission tomography in conditions involving both pain and parallel cognitive demands. The painful stimulus consisted of the standard cold pressor test and the cognitive task was a computerised perceptual maze test. The activations during the maze test reproduced findings in previous studies of the same cognitive task. The cold pressor test evoked signi®cant activity in the contralateral S1, and bilaterally in the somatosensory association areas (including S2), the ACC and the mid-insula. The activity in the somatosensory association areas and periaqueductal gray/midbrain were significantly modified, i.e. relatively decreased, when the subjects also were performing the maze task. The altered activity was accompanied with significantly lower ratings of pain during the cognitive task. In contrast, lateral orbitofrontal regions showed a relative increase of activity during pain combined with the maze task as compared to only pain, which suggests the possibility of the involvement of frontal cortex in modulation of regions processing pain
  • Pijls, F., & Kempen, G. (1986). Een psycholinguïstisch model voor grammatische samentrekking. De Nieuwe Taalgids, 79, 217-234.
  • Pijnacker, J., Geurts, B., Van Lambalgen, M., Kan, C. C., Buitelaar, J. K., & Hagoort, P. (2009). Defeasible reasoning in high-functioning adults with autism: Evidence for impaired exception-handling. Neuropsychologia, 47, 644-651. doi:10.1016/j.neuropsychologia.2008.11.011.

    Abstract

    While autism is one of the most intensively researched psychiatric disorders, little is known about reasoning skills of people with autism. The focus of this study was on defeasible inferences, that is inferences that can be revised in the light of new information. We used a behavioral task to investigate (a) conditional reasoning and (b) the suppression of conditional inferences in high-functioning adults with autism. In the suppression task a possible exception was made salient which could prevent a conclusion from being drawn. We predicted that the autism group would have difficulties dealing with such exceptions because they require mental flexibility to adjust to the context, which is often impaired in autism. The findings confirm our hypothesis that high-functioning adults with autism have a specific difficulty with exception-handling during reasoning. It is suggested that defeasible reasoning is also involved in other cognitive domains. Implications for neural underpinnings of reasoning and autism are discussed.
  • Pijnacker, J., Hagoort, P., Buitelaar, J., Teunisse, J.-P., & Geurts, B. (2009). Pragmatic inferences in high-functioning adults with autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 39(4), 607-618. doi:10.1007/s10803-008-0661-8.

    Abstract

    Although people with autism spectrum disorders (ASD) often have severe problems with pragmatic aspects of language, little is known about their pragmatic reasoning. We carried out a behavioral study on highfunctioning adults with autistic disorder (n = 11) and Asperger syndrome (n = 17) and matched controls (n = 28) to investigate whether they are capable of deriving scalar implicatures, which are generally considered to be pragmatic inferences. Participants were presented with underinformative sentences like ‘‘Some sparrows are birds’’. This sentence is logically true, but pragmatically inappropriate if the scalar implicature ‘‘Not all sparrows are birds’’ is derived. The present findings indicate that the combined ASD group was just as likely as controls to derive scalar implicatures, yet there was a difference between participants with autistic disorder and Asperger syndrome, suggesting a potential differentiation between these disorders in pragmatic reasoning. Moreover, our results suggest that verbal intelligence is a constraint for task performance in autistic disorder but not in Asperger syndrome.
  • Pine, J. M., Lieven, E. V., & Rowland, C. F. (1998). Comparing different models of the development of the English verb category. Linguistics, 36(4), 807-830. doi:10.1515/ling.1998.36.4.807.

    Abstract

    In this study data from the first six months of 12 children s multiword speech were used to test the validity of Valian's (1991) syntactic perfor-mance-limitation account and Tomasello s (1992) verb-island account of early multiword speech with particular reference to the development of the English verb category. The results provide evidence for appropriate use of verb morphology, auxiliary verb structures, pronoun case marking, and SVO word order from quite early in development. However, they also demonstrate a great deal of lexical specificity in the children's use of these systems, evidenced by a lack of overlap in the verbs to which different morphological markers were applied, a lack of overlap in the verbs with which different auxiliary verbs were used, a disproportionate use of the first person singular nominative pronoun I, and a lack of overlap in the lexical items that served as the subjects and direct objects of transitive verbs. These findings raise problems for both a syntactic performance-limitation account and a strong verb-island account of the data and suggest the need to develop a more general lexiealist account of early multiword speech that explains why some words come to function as "islands" of organization in the child's grammar and others do not.
  • Pine, J. M., Lieven, E. V., & Rowland, C. F. (1997). Stylistic variation at the “single-word” stage: Relations between maternal speech characteristics and children's vocabulary composition and usage. Child Development, 68(5), 807-819. doi:10.1111/j.1467-8624.1997.tb01963.x.

    Abstract

    In this study we test a number of different claims about the nature of stylistic variation at the “single-word” stage by examining the relation between variation in early vocabulary composition, variation in early language use, and variation in the structural and functional propreties of mothers' child-directed speech. Maternal-report and observational data were collected for 26 children at 10, 50, and 100 words, These were then correlated with a variety of different measures of maternal speech at 10 words, The results show substantial variation in the percentage of common nouns and unanalyzed phrases in children's vocabularies, and singficant relations between this variation and the way in which language is used by the child. They also reveal singficant relations between the way in whch mothers use language at 10 words and the way in chich their children use language at 50 words and between certain formal properties of mothers speech at 10 words and the percentage of common nouns and unanalyzed phrases in children's early vocabularies, However, most of these relations desappear when an attempt is made to control for ossible effects of the child on the mother at Time 1. The exception is a singficant negative correlation between mothers tendency to produce speech that illustrates word boundaries and the percentage of unanalyzed phrases at 50 and 100 words. This suggests that mothers whose sprech provides the child with information about where new words begin and end tend to have children with few unanalyzed. phrases in their early vocabularies.
  • Poletiek, F. H. (2000). De beoordelaar dobbelt niet - denkt hij. Nederlands Tijdschrift voor de Psychologie en haar Grensgebieden, 55(5), 246-249.
  • Poletiek, F. H. (1998). De geest van de jury. Psychologie en Maatschappij, 4, 376-378.
  • Poletiek, F. H. (1997). De wet 'bijzondere opnemingen in psychiatrische ziekenhuizen' aan de cijfers getoetst. Maandblad voor Geestelijke Volksgezondheid, 4, 349-361.
  • Poletiek, F. H., & Berndsen, M. (2000). Hypothesis testing as risk behaviour with regard to beliefs. Journal of Behavioral Decision Making, 13(1), 107-123. doi:10.1002/(SICI)1099-0771(200001/03)13:1<107:AID-BDM349>3.0.CO;2-P.

    Abstract

    In this paper hypothesis‐testing behaviour is compared to risk‐taking behaviour. It is proposed that choosing a suitable test for a given hypothesis requires making a preposterior analysis of two aspects of such a test: the probability of obtaining supporting evidence and the evidential value of this evidence. This consideration resembles the one a gambler makes when choosing among bets, each having a probability of winning and an amount to be won. A confirmatory testing strategy can be defined within this framework as a strategy directed at maximizing either the probability or the value of a confirming outcome. Previous theories on testing behaviour have focused on the human tendency to maximize the probability of a confirming outcome. In this paper, two experiments are presented in which participants tend to maximize the confirming value of the test outcome. Motivational factors enhance this tendency dependent on the context of the testing situation. Both this result and the framework are discussed in relation to other studies in the field of testing behaviour.
  • Poletiek, F. H. (in preparation). Inside the juror: The psychology of juror decision-making [Bespreking van De geest van de jury (1997)].
  • Poletiek, F. H., & Van Schijndel, T. J. P. (2009). Stimulus set size and statistical coverage of the grammar in artificial grammar learning. Psychonomic Bulletin & Review, 16(6), 1058-1064. doi:10.3758/PBR.16.6.1058.

    Abstract

    Adults and children acquire knowledge of the structure of their environment on the basis of repeated exposure to samples of structured stimuli. In the study of inductive learning, a straightforward issue is how much sample information is needed to learn the structure. The present study distinguishes between two measures for the amount of information in the sample: set size and the extent to which the set of exemplars statistically covers the underlying structure. In an artificial grammar learning experiment, learning was affected by the sample’s statistical coverage of the grammar, but not by its mere size. Our result suggests an alternative explanation of the set size effects on learning found in previous studies (McAndrews & Moscovitch, 1985; Meulemans & Van der Linden, 1997), because, as we argue, set size was confounded with statistical coverage in these studies. nt]mis|This research was supported by a grant from the Netherlands Organization for Scientific Research. We thank Jarry Porsius for his help with the data analyses.
  • Poletiek, F. H. (2009). Popper's Severity of Test as an intuitive probabilistic model of hypothesis testing. Behavioral and Brain Sciences, 32(1), 99-100. doi:10.1017/S0140525X09000454.
  • Poletiek, F. H., & Wolters, G. (2009). What is learned about fragments in artificial grammar learning? A transitional probabilities approach. Quarterly Journal of Experimental Psychology, 62(5), 868-876. doi:10.1080/17470210802511188.

    Abstract

    Learning local regularities in sequentially structured materials is typically assumed to be based on encoding of the frequencies of these regularities. We explore the view that transitional probabilities between elements of chunks, rather than frequencies of chunks, may be the primary factor in artificial grammar learning (AGL). The transitional probability model (TPM) that we propose is argued to provide an adaptive and parsimonious strategy for encoding local regularities in order to induce sequential structure from an input set of exemplars of the grammar. In a variant of the AGL procedure, in which participants estimated the frequencies of bigrams occurring in a set of exemplars they had been exposed to previously, participants were shown to be more sensitive to local transitional probability information than to mere pattern frequencies.
  • Powlesland, A. S., Hitchen, P. G., Parry, S., Graham, S. A., Barrio, M. M., Elola, M. T., Mordoh, J., Dell, A., Drickamer, K., & Taylor, M. E. (2009). Targeted glycoproteomic identification of cancer cell glycosylation. Glycobiology, 9, 899-909. doi:10.1093/glycob/cwp065.

    Abstract

    GalMBP is a fragment of serum mannose-binding protein that has been modified to create a probe for galactose-containing ligands. Glycan array screening demonstrated that the carbohydrate-recognition domain of GalMBP selectively binds common groups of tumor-associated glycans, including Lewis-type structures and T antigen, suggesting that engineered glycan-binding proteins such as GalMBP represent novel tools for the characterization of glycoproteins bearing tumor-associated glycans. Blotting of cell extracts and membranes from MCF7 breast cancer cells with radiolabeled GalMBP was used to demonstrate that it binds to a selected set of high molecular weight glycoproteins that could be purified from MCF7 cells on an affinity column constructed with GalMBP. Proteomic and glycomic analysis of these glycoproteins by mass spectrometry showed that they are forms of CD98hc that bear glycans displaying heavily fucosylated termini, including Lewis(x) and Lewis(y) structures. The pool of ligands was found to include the target ligands for anti-CD15 antibodies, which are commonly used to detect Lewis(x) antigen on tumors, and for the endothelial scavenger receptor C-type lectin, which may be involved in tumor metastasis through interactions with this antigen. A survey of additional breast cancer cell lines reveals that there is wide variation in the types of glycosylation that lead to binding of GalMBP. Higher levels of binding are associated either with the presence of outer-arm fucosylated structures carried on a variety of different cell surface glycoproteins or with the presence of high levels of the mucin MUC1 bearing T antigen.

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  • Praamstra, P., Stegeman, D. F., Cools, A. R., Meyer, A. S., & Horstink, M. W. I. M. (1998). Evidence for lateral premotor and parietal overactivity in Parkinson's disease during sequential and bimanual movements: A PET study. Brain, 121, 769-772. doi:10.1093/brain/121.4.769.
  • Praamstra, P., Hagoort, P., Maassen, B., & Crul, T. (1991). Word deafness and auditory cortical function: A case history and hypothesis. Brain, 114, 1197-1225. doi:10.1093/brain/114.3.1197.

    Abstract

    A patient who already had Wernick's aphasia due to a left temporal lobe lesion suffered a severe deterioration specifically of auditory language comprehension, subsequent to right temporal lobe infarction. A detailed comparison of his new condition with his language status before the second stroke revealed that the newly acquired deficit was limited to tasks related to auditory input. Further investigations demonstrated a speech perceptual disorder, which we analysed as due to deficits both at the level of general auditory processes and at the level of phonetic analysis. We discuss some arguments related to hemisphere specialization of phonetic processing and to the disconnection explanation of word deafness that support the hypothesis of word deafness being generally caused by mixed deficits.
  • Protopapas, A., & Gerakaki, S. (2009). Development of processing stress diacritics in reading Greek. Scientific Studies of Reading, 13(6), 453-483. doi:10.1080/10888430903034788.

    Abstract

    In Greek orthography, stress position is marked with a diacritic. We investigated the developmental course of processing the stress diacritic in Grades 2 to 4. Ninety children read 108 pseudowords presented without or with a diacritic either in the same or in a different position relative to the source word. Half of the pseudowords resembled the words they were derived from. Results showed that lexical sources of stress assignment were active in Grade 2 and remained stronger than the diacritic through Grade 4. The effect of the diacritic increased more rapidly and approached the lexical effect with increasing grade. In a second experiment, 90 children read 54 words and 54 pseudowords. The pattern of results for words was similar to that for nonwords suggesting that findings regarding stress assignment using nonwords may generalize to word reading. Decoding of the diacritic does not appear to be the preferred option for developing readers.
  • Pylkkänen, L., Martin, A. E., McElree, B., & Smart, A. (2009). The Anterior Midline Field: Coercion or decision making? Brain and Language, 108(3), 184-190. doi:10.1016/j.bandl.2008.06.006.

    Abstract

    To study the neural bases of semantic composition in language processing without confounds from syntactic composition, recent magnetoencephalography (MEG) studies have investigated the processing of constructions that exhibit some type of syntax-semantics mismatch. The most studied case of such a mismatch is complement coercion; expressions such as the author began the book, where an entity-denoting noun phrase is coerced into an eventive meaning in order to match the semantic properties of the event-selecting verb (e.g., ‘the author began reading/writing the book’). These expressions have been found to elicit increased activity in the Anterior Midline Field (AMF), an MEG component elicited at frontomedial sensors at ∼400 ms after the onset of the coercing noun [Pylkkänen, L., & McElree, B. (2007). An MEG study of silent meaning. Journal of Cognitive Neuroscience, 19, 11]. Thus, the AMF constitutes a potential neural correlate of coercion. However, the AMF was generated in ventromedial prefrontal regions, which are heavily associated with decision-making. This raises the possibility that, instead of semantic processing, the AMF effect may have been related to the experimental task, which was a sensicality judgment. We tested this hypothesis by assessing the effect of coercion when subjects were simply reading for comprehension, without a decision-task. Additionally, we investigated coercion in an adjectival rather than a verbal environment to further generalize the findings. Our results show that an AMF effect of coercion is elicited without a decision-task and that the effect also extends to this novel syntactic environment. We conclude that in addition to its role in non-linguistic higher cognition, ventromedial prefrontal regions contribute to the resolution of syntax-semantics mismatches in language processing.
  • Qin, S., Rijpkema, M., Tendolkar, I., Piekema, C., Hermans, E. J., Binder, M., Petersson, K. M., Luo, J., & Fernández, G. (2009). Dissecting medial temporal lobe contributions to item and associative memory formation. NeuroImage, 46, 874-881. doi:10.1016/j.neuroimage.2009.02.039.

    Abstract

    A fundamental and intensively discussed question is whether medial temporal lobe (MTL) processes that lead to non-associative item memories differ in their anatomical substrate from processes underlying associative memory formation. Using event-related functional magnetic resonance imaging, we implemented a novel design to dissociate brain activity related to item and associative memory formation not only by subsequent memory performance and anatomy but also in time, because the two constituents of each pair to be memorized were presented sequentially with an intra-pair delay of several seconds. Furthermore, the design enabled us to reduce potential differences in memory strength between item and associative memory by increasing task difficulty in the item recognition memory test. Confidence ratings for correct item recognition for both constituents did not differ between trials in which only item memory was correct and trials in which item and associative memory were correct. Specific subsequent memory analyses for item and associative memory formation revealed brain activity that appears selectively related to item memory formation in the posterior inferior temporal, posterior parahippocampal, and perirhinal cortices. In contrast, hippocampal and inferior prefrontal activity predicted successful retrieval of newly formed inter-item associations. Our findings therefore suggest that different MTL subregions indeed play distinct roles in the formation of item memory and inter-item associative memory as expected by several dual process models of the MTL memory system.
  • Reesink, G., Singer, R., & Dunn, M. (2009). Explaining the linguistic diversity of Sahul using population models. PLoS Biology, 7(11), e1000241. doi:10.1371/journal.pbio.1000241.

    Abstract

    The region of the ancient Sahul continent (present day Australia and New Guinea, and surrounding islands) is home to extreme linguistic diversity. Even apart from the huge Austronesian language family, which spread into the area after the breakup of the Sahul continent in the Holocene, there are hundreds of languages from many apparently unrelated families. On each of the subcontinents, the generally accepted classification recognizes one large, widespread family and a number of unrelatable smaller families. If these language families are related to each other, it is at a depth which is inaccessible to standard linguistic methods. We have inferred the history of structural characteristics of these languages under an admixture model, using a Bayesian algorithm originally developed to discover populations on the basis of recombining genetic markers. This analysis identifies 10 ancestral language populations, some of which can be identified with clearly defined phylogenetic groups. The results also show traces of early dispersals, including hints at ancient connections between Australian languages and some Papuan groups (long hypothesized, never before demonstrated). Systematic language contact effects between members of big phylogenetic groups are also detected, which can in some cases be identified with a diffusional or substrate signal. Most interestingly, however, there remains striking evidence of a phylogenetic signal, with many languages showing negligible amounts of admixture.
  • Richards, J. B., Waterworth, D., O'Rahilly, S., Hivert, M.-F., Loos, R. J. F., Perry, J. R. B., Tanaka, T., Timpson, N. J., Semple, R. K., Soranzo, N., Song, K., Rocha, N., Grundberg, E., Dupuis, J., Florez, J. C., Langenberg, C., Prokopenko, I., Saxena, R., Sladek, R., Aulchenko, Y. and 47 moreRichards, J. B., Waterworth, D., O'Rahilly, S., Hivert, M.-F., Loos, R. J. F., Perry, J. R. B., Tanaka, T., Timpson, N. J., Semple, R. K., Soranzo, N., Song, K., Rocha, N., Grundberg, E., Dupuis, J., Florez, J. C., Langenberg, C., Prokopenko, I., Saxena, R., Sladek, R., Aulchenko, Y., Evans, D., Waeber, G., Erdmann, J., Burnett, M.-S., Sattar, N., Devaney, J., Willenborg, C., Hingorani, A., Witteman, J. C. M., Vollenweider, P., Glaser, B., Hengstenberg, C., Ferrucci, L., Melzer, D., Stark, K., Deanfield, J., Winogradow, J., Grassl, M., Hall, A. S., Egan, J. M., Thompson, J. R., Ricketts, S. L., König, I. R., Reinhard, W., Grundy, S., Wichmann, H.-E., Barter, P., Mahley, R., Kesaniemi, Y. A., Rader, D. J., Reilly, M. P., Epstein, S. E., Stewart, A. F. R., Van Duijn, C. M., Schunkert, H., Burling, K., Deloukas, P., Pastinen, T., Samani, N. J., McPherson, R., Davey Smith, G., Frayling, T. M., Wareham, N. J., Meigs, J. B., Mooser, V., Spector, T. D., & Consortium, G. (2009). A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genetics, 5(12): e1000768. doi:10.1371/journal.pgen.1000768.

    Abstract

    The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n = 8,531) and sought validation of the lead single nucleotide polymorphisms (SNPs) in 5 additional cohorts (n = 6,202). Five SNPs were genome-wide significant in their relationship with adiponectin (P<} or =5x10(-8)). We then tested whether these 5 SNPs were associated with risk of T2D and CHD using a Bonferroni-corrected threshold of P{< or =0.011 to declare statistical significance for these disease associations. SNPs at the adiponectin-encoding ADIPOQ locus demonstrated the strongest associations with adiponectin levels (P-combined = 9.2x10(-19) for lead SNP, rs266717, n = 14,733). A novel variant in the ARL15 (ADP-ribosylation factor-like 15) gene was associated with lower circulating levels of adiponectin (rs4311394-G, P-combined = 2.9x10(-8), n = 14,733). This same risk allele at ARL15 was also associated with a higher risk of CHD (odds ratio [OR] = 1.12, P = 8.5x10(-6), n = 22,421) more nominally, an increased risk of T2D (OR = 1.11, P = 3.2x10(-3), n = 10,128), and several metabolic traits. Expression studies in humans indicated that ARL15 is well-expressed in skeletal muscle. These findings identify a novel protein, ARL15, which influences circulating adiponectin levels and may impact upon CHD risk.
  • Roelofs, A., Meyer, A. S., & Levelt, W. J. M. (1998). A case for the lemma/lexeme distinction in models of speaking: Comment on Caramazza and Miozzo (1997). Cognition, 69(2), 219-230. doi:10.1016/S0010-0277(98)00056-0.

    Abstract

    In a recent series of papers, Caramazza and Miozzo [Caramazza, A., 1997. How many levels of processing are there in lexical access? Cognitive Neuropsychology 14, 177-208; Caramazza, A., Miozzo, M., 1997. The relation between syntactic and phonological knowledge in lexical access: evidence from the 'tip-of-the-tongue' phenomenon. Cognition 64, 309-343; Miozzo, M., Caramazza, A., 1997. On knowing the auxiliary of a verb that cannot be named: evidence for the independence of grammatical and phonological aspects of lexical knowledge. Journal of Cognitive Neuropsychology 9, 160-166] argued against the lemma/lexeme distinction made in many models of lexical access in speaking, including our network model [Roelofs, A., 1992. A spreading-activation theory of lemma retrieval in speaking. Cognition 42, 107-142; Levelt, W.J.M., Roelofs, A., Meyer, A.S., 1998. A theory of lexical access in speech production. Behavioral and Brain Sciences, (in press)]. Their case was based on the observations that grammatical class deficits of brain-damaged patients and semantic errors may be restricted to either spoken or written forms and that the grammatical gender of a word and information about its form can be independently available in tip-of-the-tongue stales (TOTs). In this paper, we argue that though our model is about speaking, not taking position on writing, extensions to writing are possible that are compatible with the evidence from aphasia and speech errors. Furthermore, our model does not predict a dependency between gender and form retrieval in TOTs. Finally, we argue that Caramazza and Miozzo have not accounted for important parts of the evidence motivating the lemma/lexeme distinction, such as word frequency effects in homophone production, the strict ordering of gender and pho neme access in LRP data, and the chronometric and speech error evidence for the production of complex morphology.
  • Roelofs, A., & Meyer, A. S. (1998). Metrical structure in planning the production of spoken words. Journal of Experimental Psychology: Learning, Memory, and Cognition, 24, 922-939. doi:10.1037/0278-7393.24.4.922.

    Abstract

    According to most models of speech production, the planning of spoken words involves the independent retrieval of segments and metrical frames followed by segment-to-frame association. In some models, the metrical frame includes a specification of the number and ordering of consonants and vowels, but in the word-form encoding by activation and verification (WEAVER) model (A. Roelofs, 1997), the frame specifies only the stress pattern across syllables. In 6 implicit priming experiments, on each trial, participants produced 1 word out of a small set as quickly as possible. In homogeneous sets, the response words shared word-initial segments, whereas in heterogeneous sets, they did not. Priming effects from shared segments depended on all response words having the same number of syllables and stress pattern, but not on their having the same number of consonants and vowels. No priming occurred when the response words had only the same metrical frame but shared no segments. Computer simulations demonstrated that WEAVER accounts for the findings.
  • Roelofs, A. (1998). Rightward incrementality in encoding simple phrasal forms in speech production. Journal of Experimental Psychology: Learning, Memory, and Cognition, 24, 904-921. doi:10.1037/0278-7393.24.4.904.

    Abstract

    This article reports 7 experiments investigating whether utterances are planned in a parallel or rightward incremental fashion during language production. The experiments examined the role of linear order, length, frequency, and repetition in producing Dutch verb–particle combinations. On each trial, participants produced 1 utterance out of a set of 3 as quickly as possible. The responses shared part of their form or not. For particle-initial infinitives, facilitation was obtained when the responses shared the particle but not when they shared the verb. For verb-initial imperatives, however, facilitation was obtained for the verbs but not for the particles. The facilitation increased with length, decreased with frequency, and was independent of repetition. A simple rightward incremental model accounts quantitatively for the results.
  • Roelofs, A. (1997). The WEAVER model of word-form encoding in speech production. Cognition, 64, 249-284. doi:10.1016/S0010-0277(97)00027-9.

    Abstract

    Lexical access in speaking consists of two major steps: lemma retrieval and word-form encoding. In Roelofs (Roelofs, A. 1992a. Cognition 42. 107-142; Roelofs. A. 1993. Cognition 47, 59-87.), I described a model of lemma retrieval. The present paper extends this work by presenting a comprehensive model of the second access step, word-form encoding. The model is called WEAVER (Word-form Encoding by Activation and VERification). Unlike other models of word-form generation, WEAVER is able to provide accounts of response time data, particularly from the picture-word interference paradigm and the implicit priming paradigm. Its key features are (1) retrieval by spreading activation, (2) verification of activated information by a production rule, (3) a rightward incremental construction of phonological representations using a principle of active syllabification, syllables are constructed on the fly rather than stored with lexical items, (4) active competitive selection of syllabic motor programs using a mathematical formalism that generates response times and (5) the association of phonological speech errors with the selection of syllabic motor programs due to the failure of verification.
  • Rösler, D., & Skiba, R. (1986). Ein vernetzter Lehrmaterial-Steinbruch für Deutsch als Zweitsprache (Projekt EKMAUS, FU Berlin). Deutsch Lernen: Zeitschrift für den Sprachunterricht mit ausländischen Arbeitnehmern, 2, 68-71. Retrieved from http://www.daz-didaktik.de/html/1986.html.
  • Rossi, G. (2009). Il discorso scritto interattivo degli SMS: Uno studio pragmatico del "messaggiare". Rivista Italiana di Dialettologia, 33, 143-193. doi:10.1400/148734.
  • Rowland, C. F., & Theakston, A. L. (2009). The acquisition of auxiliary syntax: A longitudinal elicitation study. Part 2: The modals and auxiliary DO. Journal of Speech, Language, and Hearing Research, 52, 1471-1492. doi:10.1044/1092-4388(2009/08-0037a).

    Abstract

    Purpose: The study of auxiliary acquisition is central to work on language development and has attracted theoretical work from both nativist and constructivist approaches. This study is part of a 2-part companion set that represents a unique attempt to trace the development of auxiliary syntax by using a longitudinal elicitation methodology. The aim of the research described in this part is to track the development of modal auxiliaries and auxiliary DO in questions and declaratives to provide a more complete picture of the development of the auxiliary system in English-speaking children. Method: Twelve English-speaking children participated in 2 tasks designed to elicit auxiliaries CAN, WILL, and DOES in declaratives and yes/no questions. They completed each task 6 times in total between the ages of 2;10 (years;months) and 3;6. Results: The children’s levels of correct use of the target auxiliaries differed in complex ways according to auxiliary, polarity, and sentence structure, and these relations changed over development. An analysis of the children’s errors also revealed complex interactions between these factors. Conclusions: These data cannot be explained in full by existing theories of auxiliary acquisition. Researchers working within both generativist and constructivist frameworks need to develop more detailed theories of acquisition that predict the pattern of acquisition observed.
  • Rowland, C. F., & Pine, J. M. (2000). Subject-auxiliary inversion errors and wh-question acquisition: what children do know? Journal of Child Language, 27(1), 157-181.

    Abstract

    The present paper reports an analysis of correct wh-question production and subject–auxiliary inversion errors in one child's early wh-question data (age 2; 3.4 to 4; 10.23). It is argued that two current movement rule accounts (DeVilliers, 1991; Valian, Lasser & Mandelbaum, 1992) cannot explain the patterning of early wh-questions. However, the data can be explained in terms of the child's knowledge of particular lexically-specific wh-word+auxiliary combinations, and the pattern of inversion and uninversion predicted from the relative frequencies of these combinations in the mother's speech. The results support the claim that correctly inverted wh-questions can be produced without access to a subject–auxiliary inversion rule and are consistent with the constructivist claim that a distributional learning mechanism that learns and reproduces lexically-specific formulae heard in the input can explain much of the early multi-word speech data. The implications of these results for movement rule-based and constructivist theories of grammatical development are discussed.
  • De Ruiter, L. E. (2009). The prosodic marking of topical referents in the German "Vorfeld" by children and adults. The Linguistic Review, 26, 329-354. doi:10.1515/tlir.2009.012.

    Abstract

    This article reports on the analysis of prosodic marking of topical referents in the German prefield by 5- and 7-year-old children and adults. Natural speech data was obtained from a picture-elicited narration task. The data was analyzed both phonologically and phonetically. In line with previous findings, adult speakers realized topical referents predominantly with the accents L+H* and L*+H, but H* accents and unaccented items were also observed. Children used the same accent types as adults, but the accent types were distributed differently. Also, children aligned pitch minima earlier than adults and produced accents with a decreased speed of pitch change. Possible reasons for these findings are discussed. Contrast – defined in terms of a change of subjecthood – did not affect the choice of pitch accent type and did not influence phonetic realization, underlining the fact that accentuation is often a matter of individual speaker choice.

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  • Sandberg, A., Lansner, A., Petersson, K. M., & Ekeberg, Ö. (2000). A palimpsest memory based on an incremental Bayesian learning rule. Neurocomputing, 32(33), 987-994. doi:10.1016/S0925-2312(00)00270-8.

    Abstract

    Capacity limited memory systems need to gradually forget old information in order to avoid catastrophic forgetting where all stored information is lost. This can be achieved by allowing new information to overwrite old, as in the so-called palimpsest memory. This paper describes a new such learning rule employed in an attractor neural network. The network does not exhibit catastrophic forgetting, has a capacity dependent on the learning time constant and exhibits recency e!ects in retrieval
  • Scheeringa, R., Petersson, K. M., Oostenveld, R., Norris, D. G., Hagoort, P., & Bastiaansen, M. C. M. (2009). Trial-by-trial coupling between EEG and BOLD identifies networks related to alpha and theta EEG power increases during working memory maintenance. Neuroimage, 44, 1224-1238. doi:10.1016/j.neuroimage.2008.08.041.

    Abstract

    PET and fMRI experiments have previously shown that several brain regions in the frontal and parietal lobe are involved in working memory maintenance. MEG and EEG experiments have shown parametric increases with load for oscillatory activity in posterior alpha and frontal theta power. In the current study we investigated whether the areas found with fMRI can be associated with these alpha and theta effects by measuring simultaneous EEG and fMRI during a modified Sternberg task This allowed us to correlate EEG at the single trial level with the fMRI BOLD signal by forming a regressor based on single trial alpha and theta
    power estimates. We observed a right posterior, parametric alpha power increase, which was functionally related to decreases in BOLD in the primary visual cortex and in the posterior part of the right middle temporal gyrus. We relate this finding to the inhibition of neuronal activity that may interfere with WM maintenance. An observed parametric increase in frontal theta power was correlated to a decrease in BOLD in
    regions that together form the default mode network. We did not observe correlations between oscillatory EEG phenomena and BOLD in the traditional WM areas. In conclusion, the study shows that simultaneous EEG fMRI recordings can be successfully used to identify the emergence of functional networks in the brain during the execution of a cognitive task.
  • Schiller, N., Horemans, I., Ganushchak, L. Y., & Koester, D. (2009). Event-related brain potentials during monitoring of speech errors. NeuroImage, 44, 520-530. doi:10.1016/j.neuroimage.2008.09.019.

    Abstract

    When we perceive speech, our goal is to extract the meaning of the verbal message which includes semantic processing. However, how deeply do we process speech in different situations? In two experiments, native Dutch participants heard spoken sentences describing simultaneously presented pictures. Sentences either correctly described the pictures or contained an anomalous final word (i.e. a semantically or phonologically incongruent word). In the first experiment, spoken sentences were task-irrelevant and both anomalous conditions elicited similar centro-parietal N400s that were larger in amplitude than the N400 for the correct condition. In the second experiment, we ensured that participants processed the same stimuli semantically. In an early time window, we found similar phonological mismatch negativities for both anomalous conditions compared to the correct condition. These negativities were followed by an N400 that was larger for semantic than phonological errors. Together, these data suggest that we process speech semantically, even if the speech is task-irrelevant. Once listeners allocate more cognitive resources to the processing of speech, we suggest that they make predictions for upcoming words, presumably by means of the production system and an internal monitoring loop, to facilitate lexical processing of the perceived speech
  • Schiller, N. O. (1998). The effect of visually masked syllable primes on the naming latencies of words and pictures. Journal of Memory and Language, 39, 484-507. doi:10.1006/jmla.1998.2577.

    Abstract

    To investigate the role of the syllable in Dutch speech production, five experiments were carried out to examine the effect of visually masked syllable primes on the naming latencies for written words and pictures. Targets had clear syllable boundaries and began with a CV syllable (e.g., ka.no) or a CVC syllable (e.g., kak.tus), or had ambiguous syllable boundaries and began with a CV[C] syllable (e.g., ka[pp]er). In the syllable match condition, bisyllabic Dutch nouns or verbs were preceded by primes that were identical to the target’s first syllable. In the syllable mismatch condition, the prime was either shorter or longer than the target’s first syllable. A neutral condition was also included. None of the experiments showed a syllable priming effect. Instead, all related primes facilitated the naming of the targets. It is concluded that the syllable does not play a role in the process of phonological encoding in Dutch. Because the amount of facilitation increased with increasing overlap between prime and target, the priming effect is accounted for by a segmental overlap hypothesis.
  • Schiller, N. O., Meyer, A. S., & Levelt, W. J. M. (1997). The syllabic structure of spoken words: Evidence from the syllabification of intervocalic consonants. Language and Speech, 40(2), 103-140.

    Abstract

    A series of experiments was carried out to investigate the syllable affiliation of intervocalic consonants following short vowels, long vowels, and schwa in Dutch. Special interest was paid to words such as letter ['leter] ''id.,'' where a short vowel is followed by a single consonant. On phonological grounds one may predict that the first syllable should always be closed, but earlier psycholinguistic research had shown that speakers tend to leave these syllables open. In our experiments, bisyllabic word forms were presented aurally, and participants produced their syllables in reversed order (Experiments 1 through 5), or repeated the words inserting a pause between the syllables (Experiment 6). The results showed that participants generally closed syllables with a short vowel. However, in a significant number of the cases they produced open short vowel syllables. Syllables containing schwa, like syllables with a long vowel, were hardly ever closed. Word stress, the phonetic quality of the vowel in the first syllable, and the experimental context influenced syllabification. Taken together, the experiments show that native speakers syllabify bisyllabic Dutch nouns in accordance with a small set of prosodic output constraints. To account for the variability of the results, we propose that these constraints differ in their probabilities of being applied.
  • Schoffelen, J.-M., & Gross, J. (2009). Source connectivity analysis with MEG and EEG. Human Brain Mapping, 30, 1857-1865. doi: 10.1002/hbm.20745.

    Abstract

    Interactions between functionally specialized brain regions are crucial for normal brain function. Magnetoencephalography (MEG) and electroencephalography (EEG) are techniques suited to capture these interactions, because they provide whole head measurements of brain activity in the millisecond range. More than one sensor picks up the activity of an underlying source. This field spread severely limits the utility of connectivity measures computed directly between sensor recordings. Consequentially, neuronal interactions should be studied on the level of the reconstructed sources. This article reviews several methods that have been applied to investigate interactions between brain regions in source space. We will mainly focus on the different measures used to quantify connectivity, and on the different strategies adopted to identify regions of interest. Despite various successful accounts of MEG and EEG source connectivity, caution with respect to the interpretation of the results is still warranted. This is due to the fact that effects of field spread can never be completely abolished in source space. However, in this very exciting and developing field of research this cautionary note should not discourage researchers from further investigation into the connectivity between neuronal sources.
  • Schriefers, H., & Meyer, A. S. (1990). Experimental note: Cross-modal, visual-auditory picture-word interference. Bulletin of the Psychonomic Society, 28, 418-420.
  • Schriefers, H., Meyer, A. S., & Levelt, W. J. M. (1990). Exploring the time course of lexical access in language production: Picture-word interference studies. Journal of Memory and Language, 29(1), 86-102. doi:10.1016/0749-596X(90)90011-N.

    Abstract

    According to certain theories of language production, lexical access to a content word consists of two independent and serially ordered stages. In the first, semantically driven stage, so-called lemmas are retrieved, i.e., lexical items that are specified with respect to syntactic and semantic properties, but not with respect to phonological characteristics. In the second stage, the corresponding wordforms, the so-called lexemes, are retrieved. This implies that the access to a content word involves an early stage of exclusively semantic activation and a later stage of exclusively phonological activation. This seriality assumption was tested experimentally, using a picture-word interference paradigm in which the interfering words were presented auditorily. The results show an interference effect of semantically related words on picture naming latencies at an early SOA (− 150 ms), and a facilitatory effect of phonologically related words at later SOAs (0 ms, + 150 ms). On the basis of these results it can be concluded that there is indeed a stage of lexical access to a content word where only its meaning is activated, followed by a stage where only its form is activated. These findings can be seen as empirical support for a two-stage model of lexical access, or, alternatively, as putting constraints on the parameters in a network model of lexical access, such as the model proposed by Dell and Reich.
  • Schuppler, B., van Doremalen, J., Scharenborg, O., Cranen, B., & Boves, L. (2009). Using temporal information for improving articulatory-acoustic feature classification. Automatic Speech Recognition and Understanding, IEEE 2009 Workshop, 70-75. doi:10.1109/ASRU.2009.5373314.

    Abstract

    This paper combines acoustic features with a high temporal and a high frequency resolution to reliably classify articulatory events of short duration, such as bursts in plosives. SVM classification experiments on TIMIT and SVArticulatory showed that articulatory-acoustic features (AFs) based on a combination of MFCCs derived from a long window of 25ms and a short window of 5ms that are both shifted with 2.5ms steps (Both) outperform standard MFCCs derived with a window of 25 ms and a shift of 10 ms (Baseline). Finally, comparison of the TIMIT and SVArticulatory results showed that for classifiers trained on data that allows for asynchronously changing AFs (SVArticulatory) the improvement from Baseline to Both is larger than for classifiers trained on data where AFs change simultaneously with the phone boundaries (TIMIT).
  • Scott, S. K., McGettigan, C., & Eisner, F. (2009). A little more conversation, a little less action: Candidate roles for motor cortex in speech perception. Nature Reviews Neuroscience, 10(4), 295-302. doi:10.1038/nrn2603.

    Abstract

    The motor theory of speech perception assumes that activation of the motor system is essential in the perception of speech. However, deficits in speech perception and comprehension do not arise from damage that is restricted to the motor cortex, few functional imaging studies reveal activity in motor cortex during speech perception, and the motor cortex is strongly activated by many different sound categories. Here, we evaluate alternative roles for the motor cortex in spoken communication and suggest a specific role in sensorimotor processing in conversation. We argue that motor-cortex activation it is essential in joint speech, particularly for the timing of turn-taking.
  • Scott, L. J., Muglia, P., Kong, X. Q., Guan, W., Flickinger, M., Upmanyu, R., Tozzi, F., Li, J. Z., Burmeister, M., Absher, D., Thompson, R. C., Francks, C., Meng, F., Antoniades, A., Southwick, A. M., Schatzberg, A. F., Bunney, W. E., Barchas, J. D., Jones, E. G., Day, R. and 13 moreScott, L. J., Muglia, P., Kong, X. Q., Guan, W., Flickinger, M., Upmanyu, R., Tozzi, F., Li, J. Z., Burmeister, M., Absher, D., Thompson, R. C., Francks, C., Meng, F., Antoniades, A., Southwick, A. M., Schatzberg, A. F., Bunney, W. E., Barchas, J. D., Jones, E. G., Day, R., Matthews, K., McGuffin, P., Strauss, J. S., Kennedy, J. L., Middleton, L., Roses, A. D., Watson, S. J., Vincent, J. B., Myers, R. M., Farmer, A. E., Akil, H., Burns, D. K., & Boehnke, M. (2009). Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7501-7506. doi:10.1073/pnas.0813386106.

    Abstract

    Bipolar disorder (BP) is a disabling and often life-threatening disorder that affects approximately 1% of the population worldwide. To identify genetic variants that increase the risk of BP, we genotyped on the Illumina HumanHap550 Beadchip 2,076 bipolar cases and 1,676 controls of European ancestry from the National Institute of Mental Health Human Genetics Initiative Repository, and the Prechter Repository and samples collected in London, Toronto, and Dundee. We imputed SNP genotypes and tested for SNP-BP association in each sample and then performed meta-analysis across samples. The strongest association P value for this 2-study meta-analysis was 2.4 x 10(-6). We next imputed SNP genotypes and tested for SNP-BP association based on the publicly available Affymetrix 500K genotype data from the Wellcome Trust Case Control Consortium for 1,868 BP cases and a reference set of 12,831 individuals. A 3-study meta-analysis of 3,683 nonoverlapping cases and 14,507 extended controls on >2.3 M genotyped and imputed SNPs resulted in 3 chromosomal regions with association P approximately 10(-7): 1p31.1 (no known genes), 3p21 (>25 known genes), and 5q15 (MCTP1). The most strongly associated nonsynonymous SNP rs1042779 (OR = 1.19, P = 1.8 x 10(-7)) is in the ITIH1 gene on chromosome 3, with other strongly associated nonsynonymous SNPs in GNL3, NEK4, and ITIH3. Thus, these chromosomal regions harbor genes implicated in cell cycle, neurogenesis, neuroplasticity, and neurosignaling. In addition, we replicated the reported ANK3 association results for SNP rs10994336 in the nonoverlapping GSK sample (OR = 1.37, P = 0.042). Although these results are promising, analysis of additional samples will be required to confirm that variant(s) in these regions influence BP risk.

    Additional information

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  • Scott, D. R., & Cutler, A. (1984). Segmental phonology and the perception of syntactic structure. Journal of Verbal Learning and Verbal Behavior, 23, 450-466. Retrieved from http://www.sciencedirect.com/science//journal/00225371.

    Abstract

    Recent research in speech production has shown that syntactic structure is reflected in segmental phonology--the application of certain phonological rules of English (e.g., palatalization and alveolar flapping) is inhibited across phrase boundaries. We examined whether such segmental effects can be used in speech perception as cues to syntactic structure, and the relation between the use of these segmental features as syntactic markers in production and perception. Speakers of American English (a dialect in which the above segmental effects occur) could indeed use the segmental cues in syntax perception; speakers of British English (in which the effects do not occur) were unable to make use of them, while speakers of British English who were long-term residents of the United States showed intermediate performance.
  • Segaert, K., Nygård, G. E., & Wagemans, J. (2009). Identification of everyday objects on the basis of kinetic contours. Vision Research, 49(4), 417-428. doi:10.1016/j.visres.2008.11.012.

    Abstract

    Using kinetic contours derived from everyday objects, we investigated how motion affects object identification. In order not to be distinguishable when static, kinetic contours were made from random dot displays consisting of two regions, inside and outside the object contour. In Experiment 1, the dots were moving in only one of two regions. The objects were identified nearly equally well as soon as the dots either in the figure or in the background started to move. RTs decreased with increasing motion coherence levels and were shorter for complex, less compact objects than for simple, more compact objects. In Experiment 2, objects could be identified when the dots were moving both in the figure and in the background with speed and direction differences between the two. A linear increase in either the speed difference or the direction difference caused a linear decrease in RT for correct identification. In addition, the combination of speed and motion differences appeared to be super-additive.
  • Seidl, A., Cristia, A., Bernard, A., & Onishi, K. H. (2009). Allophonic and phonemic contrasts in infants' learning of sound patterns. Language Learning and Development, 5, 191-202. doi:10.1080/15475440902754326.

    Abstract

    French-learning 11-month-old and English-learning 11- and 4-month-old infants were familiarized with consonant–vowel–consonant syllables in which the final consonants were dependent on whether the preceding vowel was oral or nasal. Oral and nasal vowels are present in the ambient language of all participants, but vowel nasality is phonemic (contrastive) in French and allophonic (noncontrastive) in English. After familiarization, infants heard novel syllables that either followed or violated the familiarized patterns. French-learning 11-month-olds and English-learning 4-month-olds displayed a reliable pattern of preference demonstrating learning and generalization of the patterns, while English-learning 11-month-olds oriented equally to syllables following and violating the familiarized patterns. The results are consistent with an experience-driven reduction of attention to allophonic contrasts by as early as 11 months, which influences phonotactic learning.
  • Sekine, K. (2009). Changes in frame of reference use across the preschool years: A longitudinal study of the gestures and speech produced during route descriptions. Language and Cognitive Processes, 24(2), 218-238. doi:10.1080/01690960801941327.

    Abstract

    This study longitudinally investigated developmental changes in the frame of reference used by children in their gestures and speech. Fifteen children, between 4 and 6 years of age, were asked once a year to describe their route home from their nursery school. When the children were 4 years old, they tended to produce gestures that directly and continuously indicated their actual route in a large gesture space. In contrast, as 6-year-olds, their gestures were segmented and did not match the actual route. Instead, at age 6, the children seemed to create a virtual space in front of themselves to symbolically describe their route. These results indicate that the use of frames of reference develops across the preschool years, shifting from an actual environmental to an abstract environmental frame of reference. Factors underlying the development of frame of reference, including verbal encoding skills and experience, are discussed.
  • Senft, G. (1998). Body and mind in the Trobriand Islands. Ethos, 26, 73-104. doi:10.1525/eth.1998.26.1.73.

    Abstract

    This article discusses how the Trobriand Islanders speak about body and mind. It addresses the following questions: do the linguistic datafit into theories about lexical universals of body-part terminology? Can we make inferences about the Trobrianders' conceptualization of psychological and physical states on the basis of these data? If a Trobriand Islander sees these idioms as external manifestations of inner states, then can we interpret them as a kind of ethnopsychological theory about the body and its role for emotions, knowledge, thought, memory, and so on? Can these idioms be understood as representation of Trobriand ethnopsychological theory?
  • Senft, G. (1998). [Review of the book Anthropological linguistics: An introduction by William A. Foley]. Linguistics, 36, 995-1001.
  • Senft, G. (1991). [Review of the book Einführung in die deskriptive Linguistik by Michael Dürr and Peter Schlobinski]. Linguistics, 29, 722-725.
  • Senft, G. (2009). [Review of the book Geschichten und Gesänge von der Insel Nias in Indonesien ed. by Johannes Maria Hämmerle]. Rundbrief - Forum für Mitglieder des Pazifik-Netzwerkes e.V., 78/09, 29-31.
  • Senft, G. (1990). [Review of the book Intergrammar by H. Arndt, & R.W. Janney]. System, 18(1), 112-114. doi:10.1016/0346-251X(90)90036-5.
  • Senft, G. (2000). [Review of the book Language, identity, and marginality in Indonesia: The changing nature of ritual speech on the island of Sumba by Joel C. Kuipers]. Linguistics, 38, 435-441. doi:10.1515/ling.38.2.435.
  • Senft, G. (1990). [Review of the book Noun classes and categorization ed. by Colette Craig]. Acta Linguistica Hafniensia, 22, 173-180.
  • Senft, G. (1997). [Review of the book The design of language: An introduction to descriptive linguistics by Terry Crowley, John Lynch, Jeff Siegel, and Julie Piau]. Linguistics, 35, 781-785.
  • Senft, G. (1991). [Review of the book The sign languages of Aboriginal Australia by Adam Kendon]. Journal of Pragmatics, 15, 400-405. doi:10.1016/0378-2166(91)90040-5.
  • Senft, G. (1986). [Review of the book Under the Tumtum tree: From nonsense to sense in nonautomatic comprehension by Marlene Dolitsky]. Journal of Pragmatics, 10, 273-278. doi:10.1016/0378-2166(86)90094-9.
  • Senft, G. (1997). Magical conversation on the Trobriand Islands. Anthropos, 92, 369-391.
  • Senft, G. (1991). Network models to describe the Kilivila classifier system. Oceanic Linguistics, 30, 131-155. Retrieved from http://www.jstor.org/stable/3623085.
  • Senft, B., & Senft, G. (1986). Ninikula - Fadenspiele auf den Trobriand Inseln: Untersuchungen zum Spiele-Repertoire unter besonderer Berürcksichtigung der Spiel-begeleitenden Texte. Baessler Archiv: Beiträge zur Völkerkunde, N.F. 34, 92-235.
  • Senft, G., & Senft, B. (1986). Ninikula Fadenspiele auf den Trobriand-Inseln, Papua-Neuguinea: Untersuchungen zum Spiele-Repertoire unter besonderer Berücksichtigung der Spiel-begleitendenden Texte. Baessler-Archiv: Beiträge zur Völkerkunde, 34(1), 93-235.
  • Senft, G. (1990). Yoreshiawes Klagelied anläßlich des Todes seiner kleinen Tochter. Forschungsstelle für Humanethologie in der MPG. Berichte und Mitteilungen; 1/90, 23-24.
  • Seuren, P. A. M. (2000). Bewustzijn en taal. Splijtstof, 28(4), 111-123.
  • Seuren, P. A. M. (1990). Burton-Roberts on presupposition and negation. Journal of Linguistics, 26(2), 425-453. doi:10.1017/S0022226700014730.

    Abstract

    In his paper ‘On Horn's dilemma: presupposition and negation’ Burton-Roberts (1989a) presents an ambitious programme, formulated right at the outset. He seeks to establish three points: (i) Under the ‘standard logical definition of presupposition’ a pre-suppositional semantics is INCOMPATIBLE with a SEMANTICALLY AMBIGUOUS NEGATION operator (SAN), on pain of the theory being rendered ‘empirically empty and theoretically trivial’,. (ii) From this it follows that the one unambiguous negation is presupposition preserving. Cases that have been identified as presupposition-cancelling negation should be re-analysed as ‘instances of a pragmatic phenomenon’, not unlike what has been proposed in Horn (1985), that is as METALINGUISTIC NEGATION (MN). (iii) This pragmatic analysis of MN ‘itself implies a presuppositional semantics’, that is to say ‘a presuppositional theory of truth-value gaps’.
  • Seuren, P. A. M. (1986). Adjectives as adjectives in Sranan. Journal of Pidgin and Creole Languages, 1(1), 123-134.
  • Seuren, P. A. M. (2009). Concerning the roots of transformational generative grammar [Review article]. Historiographia Linguistica, 36, 97-115. doi:10.1075/hl.36.1.05seu.
  • Seuren, P. A. M. (1990). [Review of the book A life for language: A biographical memoir of Leonard Bloomfield by Robert A. Hall]. Linguistics, 29(4), 753-757. doi:10.1515/ling.1991.29.4.719.
  • Seuren, P. A. M. (1998). [Review of the book Adverbial subordination; A typology and history of adverbial subordinators based on European languages by Bernd Kortmann]. Cognitive Linguistics, 9(3), 317-319. doi:10.1515/cogl.1998.9.3.315.
  • Seuren, P. A. M. (1997). [Review of the book Schets van de Nederlandse Taal. Grammatica, poëtica en retorica by Adriaen Verwer, Naar de editie van E. van Driel (1783) vertaald door J. Knol. Ed. Th.A.J.M. Janssen & J. Noordegraaf]. Nederlandse Taalkunde, 4, 370-374.
  • Seuren, P. A. M. (1998). [Review of the book The Dutch pendulum: Linguistics in the Netherlands 1740-1900 by Jan Noordegraaf]. Bulletin of the Henry Sweet Society, 31, 46-50.
  • Seuren, P. A. M. (1990). [Review of the book The limits to debate: A revised theory of presupposition by N. Burton-Roberts]. Linguistics, 28(3), 503-516. doi:10.1515/ling.1990.28.3.503.
  • Seuren, P. A. M. (1986). Formal theory and the ecology of language. Theoretical Linguistics, 13(1), 1-18. doi:10.1515/thli.1986.13.1-2.1.
  • Seuren, P. A. M. (1963). Naar aanleiding van Dr. F. Balk-Smit Duyzentkunst "De Grammatische Functie". Levende Talen, 219, 179-186.
  • Seuren, P. A. M. (1986). La transparence sémantique et la genèse des langues créoles: Le cas du Créole mauricien. Études Créoles, 9, 169-183.
  • Seuren, P. A. M. (1991). Grammatika als algorithme: Rekenen met taal. Koninklijke Nederlandse Akademie van Wetenschappen. Mededelingen van de Afdeling Letterkunde, Nieuwe Reeks, 54(2), 25-63.
  • Seuren, P. A. M. (1986). Helpen en helpen is twee. Glot, 9(1/2), 110-117.
  • Seuren, P. A. M., & Mufwene, S. S. (1990). Introduction. Linguistics, 28(4), 641-643. doi:10.1515/ling.1990.28.4.641.
  • Seuren, P. A. M., & Mufwene, S. S. (Eds.). (1990). Issues in Creole lingusitics [Special Issue]. Linguistics, 28(4).
  • Seuren, P. A. M. (1989). Neue Entwicklungen im Wahrheitsbegriff. Studia Leibnitiana, 21(2), 155-173.
  • Seuren, P. A. M. (1998). Obituary. Herman Christiaan Wekker 1943–1997. Journal of Pidgin and Creole Languages, 13(1), 159-162.
  • Seuren, P. A. M. (1984). Operator lowering. Linguistics, 22(5), 573-627. doi:10.1515/ling.1984.22.5.573.
  • Seuren, P. A. M. (2000). Presupposition, negation and trivalence. Journal of Linguistics, 36(2), 261-297.
  • Seuren, P. A. M. (1984). The bioprogram hypothesis: Facts and fancy. A commentary on Bickerton "The language bioprogram hypothesis". Behavioral and Brain Sciences, 7(2), 208-209. doi:10.1017/S0140525X00044356.
  • Seuren, P. A. M. (2009). The clitics mechanism in French and Italian. Probus, 21(1), 83-142. doi:10.1515/prbs.2009.004.

    Abstract

    The article concentrates on the question of the composition, the internal ordering and the placement of clitic-clusters (C-clusters) in French and Italian, though clitic data from other languages are drawn in occasionally. The system proposed is top-down transformational, in the terms of Semantic Syntax (Seuren, Blackwell, 1996). Clitics are taken to originate in underlying structure as canonical argument terms or adverbial constituents of clauses. During the process of transformation from semantic to surface form, nonfocus, nonsubject, pronominal argument terms are assigned values for the features of animacy ([±an]), dative status ([±dat]) and reflexivity ([±refl]). On the basis of these, the rule feature cm, inducing clitic movement, is assigned or withheld. Plus-values increase, and minus-values reduce, the “semantic weight” of the clitics in question. Pronouns without the feature cm are not cliticised and stay in their canonical term position in their full phonological form. Pronouns with the feature cm are attached to the nearest verb form giving rise to clitic clusters, which accounts for the composition of well-formed C-clusters. The attachment of clitics to a cluster occurs in a fixed order, which accounts for the ordering of clitics in well-formed clusters. Branching directionality, together with a theory of complementation, accounts for the placement of C-clusters. Clitics often take on a reduced phonological form. It is argued that, in French and Italian, which are languages with a right-branching syntax and a left-branching flectional morphology, postverbal clitics, or enclitics, are part of left-branching structures and hence fit naturally into the morphology. They are best categorised as affixes. Occasionally, as in Italian glielo, dative clitics (e.g., gli) turn preceding lighter clitics (e.g., lo) into affixes, resulting in the left-branching structure glielo, where -lo is an affix. In a brief Intermezzo, instances are shown of the irregular but revealing lui-le-lui phenomenon in French, and its much less frequent analog in Italian. On these assumptions, supported by the official orthographies, the clitic systems of French and Italian largely coincide. This new analysis of the facts in question invites further reflection on the interface between syntax and morphology. The final section deals with reflexive clitics. There, the system begins to be unable to account for the observed facts. At this end, therefore, the system is allowed to remain fraying, till further research brings greater clarity.
  • Seuren, P. A. M. (1984). The comparative revisited. Journal of Semantics, 3(1), 109-141. doi:10.1093/jos/3.1-2.109.
  • Seuren, P. A. M. (1990). Still no serials in Seselwa: A Reply to "Seselwa Serialization and its Significance" by Derek Bickerton. Journal of Pidgin and Creole Languages, 5(2), 271-292.
  • Seuren, P. A. M., & Hamans, C. (2009). Semantic conditioning of syntactic rules: Evidentiality and auxiliation in English and Dutch. Folia Linguistica, 43(1), 135-169. doi:10.1515/FLIN.2009.004.

    Abstract

    Ever since the category of evidentiality has been identified in the verbal grammar of certain languages, it has been assumed that evidentiality plays no role in the grammars of those languages that have not incorporated it into their verb morphology or at least their verb clusters. The present paper attempts to show that even if evidentiality is not visible in the verbal grammar of English and Dutch, it appears to be a motivating factor, both historically and synchronically, in the process whereby evidential predicates are made to play a subordinate syntactic role with regard to their embedded subject clause. This process, known as AUXILIATION (Kuteva 2001), appears to manifest itself in a variety of, often successive, grammatical processes or rules, such as Subject-to-Subject Raising (the subject of the embedded clause becomes the subject of the main verb, as in John is likely to be late), V-ING (as in The man stopped breathing), Incorporation-by-Lowering (the evidential main verb is lowered on to the V-constituent of the embedded subject clause, as in John may have left), or Incorporation-by-Raising (also known as Predicate Raising), not or hardly attested in English but dominant in Dutch. A list is provided of those English (and Dutch) predicates that induce one of the above-mentioned auxiliation rules and it is checked how many of those have an evidential meaning. This is set off against evidential predicates that do not induce an auxiliation rule. It results that, for English and Dutch, lexical evidentiality is a powerful determinant for the induction of syntactic auxiliation.
  • Seuren, P. A. M. (1986). The self-styling of relevance theory [Review of the book Relevance, Communication and Cognition by Dan Sperber and Deirdre Wilson]. Journal of Semantics, 5(2), 123-143. doi:10.1093/jos/5.2.123.
  • Seuren, P. A. M. (1990). Verb syncopation and predicate raising in Mauritian Creole. Linguistics, 28(4), 809-844. doi:10.1515/ling.1990.28.4.809.
  • Shopen, T., Reid, N., Shopen, G., & Wilkins, D. G. (1997). Ensuring the survival of Aboriginal and Torres Strait islander languages into the 21st century. Australian Review of Applied Linguistics, 10(1), 143-157.

    Abstract

    Aboriginal languages threatened by speakers poor economic and social conditions; some may survive through support for community development, language maintenance, bilingual education and training of Aboriginal teachers and linguists, and nonAboriginal teachers of Aboriginal and Islander students.
  • Simon-Thomas, E. R., Keltner, D. J., Sauter, D., Sinicropi-Yao, L., & Abramson, A. (2009). The voice conveys specific emotions: Evidence from vocal burst displays. Emotion, 9, 838-846. doi:10.1037/a0017810.

    Abstract

    Studies of emotion signaling inform claims about the taxonomic structure, evolutionary origins, and physiological correlates of emotions. Emotion vocalization research has tended to focus on a limited set of emotions: anger, disgust, fear, sadness, surprise, happiness, and for the voice, also tenderness. Here, we examine how well brief vocal bursts can communicate 22 different emotions: 9 negative (Study 1) and 13 positive (Study 2), and whether prototypical vocal bursts convey emotions more reliably than heterogeneous vocal bursts (Study 3). Results show that vocal bursts communicate emotions like anger, fear, and sadness, as well as seldom-studied states like awe, compassion, interest, and embarrassment. Ancillary analyses reveal family-wise patterns of vocal burst expression. Errors in classification were more common within emotion families (e.g., ‘self-conscious,’ ‘pro-social’) than between emotion families. The three studies reported highlight the voice as a rich modality for emotion display that can inform fundamental constructs about emotion.

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