Publications

Displaying 301 - 400 of 855
  • Hope, T. M. H., Neville, D., Talozzi, L., Foulon, C., Forkel, S. J., Thiebaut de Schotten, M., & Price, C. J. (2024). Testing the disconnectome symptom discoverer model on out-of-sample post-stroke language outcomes. Brain, 147(2), e11-e13. doi:10.1093/brain/awad352.

    Abstract

    Stroke is common, and its consequent brain damage can cause various cognitive impairments. Associations between where and how much brain lesion damage a patient has suffered, and the particular impairments that injury has caused (lesion-symptom associations) offer potentially compelling insights into how the brain implements cognition.1 A better understanding of those associations can also fill a gap in current stroke medicine by helping us to predict how individual patients might recover from post-stroke impairments.2 Most recent work in this area employs machine learning models trained with data from stroke patients whose mid-to-long-term outcomes are known.2-4 These machine learning models are tested by predicting new outcomes—typically scores on standardized tests of post-stroke impairment—for patients whose data were not used to train the model. Traditionally, these validation results have been shared in peer-reviewed publications describing the model and its training. But recently, and for the first time in this field (as far as we know), one of these pre-trained models has been made public—The Disconnectome Symptom Discoverer model (DSD) which draws its predictors from structural disconnection information inferred from stroke patients’ brain MRI.5

    Here, we test the DSD model on wholly independent data, never seen by the model authors, before they published it. Specifically, we test whether its predictive performance is just as accurate as (i.e. not significantly worse than) that reported in the original (Washington University) dataset, when predicting new patients’ outcomes at a similar time post-stroke (∼1 year post-stroke) and also in another independent sample tested later (5+ years) post-stroke. A failure to generalize the DSD model occurs if it performs significantly better in the Washington data than in our data from patients tested at a similar time point (∼1 year post-stroke). In addition, a significant decrease in predictive performance for the more chronic sample would be evidence that lesion-symptom associations differ at ∼1 year post-stroke and >5 years post-stroke.
  • Horton, S., Jackson, V., Boyce, J., Franken, M.-C., Siemers, S., St John, M., Hearps, S., Van Reyk, O., Braden, R., Parker, R., Vogel, A. P., Eising, E., Amor, D. J., Irvine, J., Fisher, S. E., Martin, N. G., Reilly, S., Bahlo, M., Scheffer, I., & Morgan, A. (2023). Self-reported stuttering severity is accurate: Informing methods for large-scale data collection in stuttering. Journal of Speech, Language, and Hearing Research. Advance online publication. doi:10.1044/2023_JSLHR-23-00081.

    Abstract

    Purpose:
    To our knowledge, there are no data examining the agreement between self-reported and clinician-rated stuttering severity. In the era of big data, self-reported ratings have great potential utility for large-scale data collection, where cost and time preclude in-depth assessment by a clinician. Equally, there is increasing emphasis on the need to recognize an individual's experience of their own condition. Here, we examined the agreement between self-reported stuttering severity compared to clinician ratings during a speech assessment. As a secondary objective, we determined whether self-reported stuttering severity correlated with an individual's subjective impact of stuttering.

    Method:
    Speech-language pathologists conducted face-to-face speech assessments with 195 participants (137 males) aged 5–84 years, recruited from a cohort of people with self-reported stuttering. Stuttering severity was rated on a 10-point scale by the participant and by two speech-language pathologists. Participants also completed the Overall Assessment of the Subjective Experience of Stuttering (OASES). Clinician and participant ratings were compared. The association between stuttering severity and the OASES scores was examined.

    Results:
    There was a strong positive correlation between speech-language pathologist and participant-reported ratings of stuttering severity. Participant-reported stuttering severity correlated weakly with the four OASES domains and with the OASES overall impact score.

    Conclusions:
    Participants were able to accurately rate their stuttering severity during a speech assessment using a simple one-item question. This finding indicates that self-report stuttering severity is a suitable method for large-scale data collection. Findings also support the collection of self-report subjective experience data using questionnaires, such as the OASES, which add vital information about the participants' experience of stuttering that is not captured by overt speech severity ratings alone.
  • De Hoyos, L., Barendse, M. T., Schlag, F., Van Donkelaar, M. M. J., Verhoef, E., Shapland, C. Y., Klassmann, A., Buitelaar, J., Verhulst, B., Fisher, S. E., Rai, D., & St Pourcain, B. (2024). Structural models of genome-wide covariance identify multiple common dimensions in autism. Nature Communications, 15: 1770. doi:10.1038/s41467-024-46128-8.

    Abstract

    Common genetic variation has been associated with multiple symptoms in Autism Spectrum Disorder (ASD). However, our knowledge of shared genetic factor structures contributing to this highly heterogeneous neurodevelopmental condition is limited. Here, we developed a structural equation modelling framework to directly model genome-wide covariance across core and non-core ASD phenotypes, studying autistic individuals of European descent using a case-only design. We identified three independent genetic factors most strongly linked to language/cognition, behaviour and motor development, respectively, when studying a population-representative sample (N=5,331). These analyses revealed novel associations. For example, developmental delay in acquiring personal-social skills was inversely related to language, while developmental motor delay was linked to self-injurious behaviour. We largely confirmed the three-factorial structure in independent ASD-simplex families (N=1,946), but uncovered simplex-specific genetic overlap between behaviour and language phenotypes. Thus, the common genetic architecture in ASD is multi-dimensional and contributes, in combination with ascertainment-specific patterns, to phenotypic heterogeneity.
  • Huang, L., Zhou, G., Liu, Z., Dang, X., Yang, Z., Kong, X., Wang, X., Song, Y., Zhen, Z., & Liu, J. (2016). A Multi-Atlas Labeling Approach for Identifying Subject-Specific Functional Regions of Interest. PLoS One, 11(1): e0146868. doi:10.1371/journal.pone.0146868.

    Abstract

    The functional region of interest (fROI) approach has increasingly become a favored methodology in functional magnetic resonance imaging (fMRI) because it can circumvent inter-subject anatomical and functional variability, and thus increase the sensitivity and functional resolution of fMRI analyses. The standard fROI method requires human experts to meticulously examine and identify subject-specific fROIs within activation clusters. This process is time-consuming and heavily dependent on experts’ knowledge. Several algorithmic approaches have been proposed for identifying subject-specific fROIs; however, these approaches cannot easily incorporate prior knowledge of inter-subject variability. In the present study, we improved the multi-atlas labeling approach for defining subject-specific fROIs. In particular, we used a classifier-based atlas-encoding scheme and an atlas selection procedure to account for the large spatial variability across subjects. Using a functional atlas database for face recognition, we showed that with these two features, our approach efficiently circumvented inter-subject anatomical and functional variability and thus improved labeling accuracy. Moreover, in comparison with a single-atlas approach, our multi-atlas labeling approach showed better performance in identifying subject-specific fROIs.

    Additional information

    S1_Fig.tif S2_Fig.tif
  • Hubers, F., Snijders, T. M., & De Hoop, H. (2016). How the brain processes violations of the grammatical norm: An fMRI study. Brain and Language, 163, 22-31. doi:10.1016/j.bandl.2016.08.006.

    Abstract

    Native speakers of Dutch do not always adhere to prescriptive grammar rules in their daily speech. These grammatical norm violations can elicit emotional reactions in language purists, mostly high-educated people, who claim that for them these constructions are truly ungrammatical. However, linguists generally assume that grammatical norm violations are in fact truly grammatical, especially when they occur frequently in a language. In an fMRI study we investigated the processing of grammatical norm violations in the brains of language purists, and compared them with truly grammatical and truly ungrammatical sentences. Grammatical norm violations were found to be unique in that their processing resembled not only the processing of truly grammatical sentences (in left medial Superior Frontal Gyrus and Angular Gyrus), but also that of truly ungrammatical sentences (in Inferior Frontal Gyrus), despite what theories of grammar would usually lead us to believe
  • Huettig, F., & Janse, E. (2016). Individual differences in working memory and processing speed predict anticipatory spoken language processing in the visual world. Language, Cognition and Neuroscience, 31(1), 80-93. doi:10.1080/23273798.2015.1047459.

    Abstract

    It is now well established that anticipation of up-coming input is a key characteristic of spoken language comprehension. Several mechanisms of predictive language processing have been proposed. The possible influence of mediating factors such as working memory and processing speed however has hardly been explored. We sought to find evidence for such an influence using an individual differences approach. 105 participants from 32 to 77 years of age received spoken instructions (e.g., "Kijk naar deCOM afgebeelde pianoCOM" - look at the displayed piano) while viewing four objects. Articles (Dutch “het” or “de”) were gender-marked such that the article agreed in gender only with the target. Participants could thus use gender information from the article to predict the upcoming target object. The average participant anticipated the target objects well in advance of the critical noun. Multiple regression analyses showed that working memory and processing speed had the largest mediating effects: Enhanced working memory abilities and faster processing speed supported anticipatory spoken language processing. These findings suggest that models of predictive language processing must take mediating factors such as working memory and processing speed into account. More generally, our results are consistent with the notion that working memory grounds language in space and time, linking linguistic and visual-spatial representations.
  • Huettig, F., & Mani, N. (2016). Is prediction necessary to understand language? Probably not. Language, Cognition and Neuroscience, 31(1), 19-31. doi:10.1080/23273798.2015.1072223.

    Abstract

    Many psycholinguistic experiments suggest that prediction is an important characteristic of language processing. Some recent theoretical accounts in the cognitive sciences (e.g., Clark, 2013; Friston, 2010) and psycholinguistics (e.g., Dell & Chang, 2014) appear to suggest that prediction is even necessary to understand language. In the present opinion paper we evaluate this proposal. We first critically discuss several arguments that may appear to be in line with the notion that prediction is necessary for language processing. These arguments include that prediction provides a unified theoretical principle of the human mind and that it pervades cortical function. We discuss whether evidence of human abilities to detect statistical regularities is necessarily evidence for predictive processing and evaluate suggestions that prediction is necessary for language learning. Five arguments are then presented that question the claim that all language processing is predictive in nature. We point out that not all language users appear to predict language and that suboptimal input makes prediction often very challenging. Prediction, moreover, is strongly context-dependent and impeded by resource limitations. We also argue that it may be problematic that most experimental evidence for predictive language processing comes from 'prediction-encouraging' experimental set-ups. Finally, we discuss possible ways that may lead to a further resolution of this debate. We conclude that languages can be learned and understood in the absence of prediction. Claims that all language processing is predictive in nature are premature.
  • Huettig, F., Voeten, C. C., Pascual, E., Liang, J., & Hintz, F. (2023). Do autistic children differ in language-mediated prediction? Cognition, 239: 105571. doi:10.1016/j.cognition.2023.105571.

    Abstract

    Prediction appears to be an important characteristic of the human mind. It has also been suggested that prediction is a core difference of autistic children. Past research exploring language-mediated anticipatory eye movements in autistic children, however, has been somewhat contradictory, with some studies finding normal anticipatory processing in autistic children with low levels of autistic traits but others observing weaker prediction effects in autistic children with less receptive language skills. Here we investigated language-mediated anticipatory eye movements in young children who differed in the severity of their level of autistic traits and were in professional institutional care in Hangzhou, China. We chose the same spoken sentences (translated into Mandarin Chinese) and visual stimuli as a previous study which observed robust prediction effects in young children (Mani & Huettig, 2012) and included a control group of typically-developing children. Typically developing but not autistic children showed robust prediction effects. Most interestingly, autistic children with lower communication, motor, and (adaptive) behavior scores exhibited both less predictive and non-predictive visual attention behavior. Our results raise the possibility that differences in language-mediated anticipatory eye movements in autistic children with higher levels of autistic traits may be differences in visual attention in disguise, a hypothesis that needs further investigation.
  • Huettig, F., & Ferreira, F. (2023). The myth of normal reading. Perspectives on Psychological Science, 18(4), 863-870. doi:10.1177/17456916221127226.

    Abstract

    We argue that the educational and psychological sciences must embrace the diversity of reading rather than chase the phantom of normal reading behavior. We critically discuss the research practice of asking participants in experiments to read “normally”. We then draw attention to the large cross-cultural and linguistic diversity around the world and consider the enormous diversity of reading situations and goals. Finally, we observe that people bring a huge diversity of brains and experiences to the reading task. This leads to certain implications. First, there are important lessons for how to conduct psycholinguistic experiments. Second, we need to move beyond Anglo-centric reading research and produce models of reading that reflect the large cross-cultural diversity of languages and types of writing systems. Third, we must acknowledge that there are multiple ways of reading and reasons for reading, and none of them is normal or better or a “gold standard”. Finally, we must stop stigmatizing individuals who read differently and for different reasons, and there should be increased focus on teaching the ability to extract information relevant to the person’s goals. What is important is not how well people decode written language and how fast people read but what people comprehend given their own stated goals.
  • Huettig, F., & Hulstijn, J. (2024). The Enhanced Literate Mind Hypothesis. Topics in Cognitive Science. Advance online publication. doi:10.1111/tops.12731.

    Abstract

    In the present paper we describe the Enhanced Literate Mind (ELM) hypothesis. As individuals learn to read and write, they are, from then on, exposed to extensive written-language input and become literate. We propose that acquisition and proficient processing of written language (‘literacy’) leads to, both, increased language knowledge as well as enhanced language and non-language (perceptual and cognitive) skills. We also suggest that all neurotypical native language users, including illiterate, low literate, and high literate individuals, share a Basic Language Cognition (BLC) in the domain of oral informal language. Finally, we discuss the possibility that the acquisition of ELM leads to some degree of ‘knowledge parallelism’ between BLC and ELM in literate language users, which has implications for empirical research on individual and situational differences in spoken language processing.
  • Hugh-Jones, D., Verweij, K. J. H., St Pourcain, B., & Abdellaoui, A. (2016). Assortative mating on educational attainment leads to genetic spousal resemblance for causal alleles. Intelligence, 59, 103-108. doi:10.1016/j.intell.2016.08.005.

    Abstract

    We examined whether assortative mating for educational attainment (“like marries like”) can be detected in the genomes of ~ 1600 UK spouse pairs of European descent. Assortative mating on heritable traits like educational attainment increases the genetic variance and heritability of the trait in the population, which may increase social inequalities. We test for genetic assortative mating in the UK on educational attainment, a phenotype that is indicative of socio-economic status and has shown substantial levels of assortative mating. We use genome-wide allelic effect sizes from a large genome-wide association study on educational attainment (N ~ 300 k) to create polygenic scores that are predictive of educational attainment in our independent sample (r = 0.23, p < 2 × 10− 16). The polygenic scores significantly predict partners' educational outcome (r = 0.14, p = 4 × 10− 8 and r = 0.19, p = 2 × 10− 14, for prediction from males to females and vice versa, respectively), and are themselves significantly correlated between spouses (r = 0.11, p = 7 × 10− 6). Our findings provide molecular genetic evidence for genetic assortative mating on education in the UK
  • Huisman, J. L. A., Van Hout, R., & Majid, A. (2023). Cross-linguistic constraints and lineage-specific developments in the semantics of cutting and breaking in Japonic and Germanic. Linguistic Typology, 27(1), 41-75. doi:10.1515/lingty-2021-2090.

    Abstract

    Semantic variation in the cutting and breaking domain has been shown to be constrained across languages in a previous typological study, but it was unclear whether Japanese was an outlier in this domain. Here we revisit cutting and breaking in the Japonic language area by collecting new naming data for 40 videoclips depicting cutting and breaking events in Standard Japanese, the highly divergent Tohoku dialects, as well as four related Ryukyuan languages (Amami, Okinawa, Miyako and Yaeyama). We find that the Japonic languages recapitulate the same semantic dimensions attested in the previous typological study, confirming that semantic variation in the domain of cutting and breaking is indeed cross-linguistically constrained. We then compare our new Japonic data to previously collected Germanic data and find that, in general, related languages resemble each other more than unrelated languages, and that the Japonic languages resemble each other more than the Germanic languages do. Nevertheless, English resembles all of the Japonic languages more than it resembles Swedish. Together, these findings show that the rate and extent of semantic change can differ between language families, indicating the existence of lineage-specific developments on top of universal cross-linguistic constraints.
  • Huizeling, E., Alday, P. M., Peeters, D., & Hagoort, P. (2023). Combining EEG and 3D-eye-tracking to study the prediction of upcoming speech in naturalistic virtual environments: A proof of principle. Neuropsychologia, 191: 108730. doi:10.1016/j.neuropsychologia.2023.108730.

    Abstract

    EEG and eye-tracking provide complementary information when investigating language comprehension. Evidence that speech processing may be facilitated by speech prediction comes from the observation that a listener's eye gaze moves towards a referent before it is mentioned if the remainder of the spoken sentence is predictable. However, changes to the trajectory of anticipatory fixations could result from a change in prediction or an attention shift. Conversely, N400 amplitudes and concurrent spectral power provide information about the ease of word processing the moment the word is perceived. In a proof-of-principle investigation, we combined EEG and eye-tracking to study linguistic prediction in naturalistic, virtual environments. We observed increased processing, reflected in theta band power, either during verb processing - when the verb was predictive of the noun - or during noun processing - when the verb was not predictive of the noun. Alpha power was higher in response to the predictive verb and unpredictable nouns. We replicated typical effects of noun congruence but not predictability on the N400 in response to the noun. Thus, the rich visual context that accompanied speech in virtual reality influenced language processing compared to previous reports, where the visual context may have facilitated processing of unpredictable nouns. Finally, anticipatory fixations were predictive of spectral power during noun processing and the length of time fixating the target could be predicted by spectral power at verb onset, conditional on the object having been fixated. Overall, we show that combining EEG and eye-tracking provides a promising new method to answer novel research questions about the prediction of upcoming linguistic input, for example, regarding the role of extralinguistic cues in prediction during language comprehension.
  • Humphries, S., Holler, J., Crawford, T. J., Herrera, E., & Poliakoff, E. (2016). A third-person perspective on co-speech action gestures in Parkinson’s disease. Cortex, 78, 44-54. doi:10.1016/j.cortex.2016.02.009.

    Abstract

    A combination of impaired motor and cognitive function in Parkinson’s disease (PD) can impact on language and communication, with patients exhibiting a particular difficulty processing action verbs. Co-speech gestures embody a link between action and language and contribute significantly to communication in healthy people. Here, we investigated how co-speech gestures depicting actions are affected in PD, in particular with respect to the visual perspective—or the viewpoint – they depict. Gestures are closely related to mental imagery and motor simulations, but people with PD may be impaired in the way they simulate actions from a first-person perspective and may compensate for this by relying more on third-person visual features. We analysed the action-depicting gestures produced by mild-moderate PD patients and age-matched controls on an action description task and examined the relationship between gesture viewpoint, action naming, and performance on an action observation task (weight judgement). Healthy controls produced the majority of their action gestures from a first-person perspective, whereas PD patients produced a greater proportion of gestures produced from a third-person perspective. We propose that this reflects a compensatory reliance on third-person visual features in the simulation of actions in PD. Performance was also impaired in action naming and weight judgement, although this was unrelated to gesture viewpoint. Our findings provide a more comprehensive understanding of how action-language impairments in PD impact on action communication, on the cognitive underpinnings of this impairment, as well as elucidating the role of action simulation in gesture production
  • Hustá, C., Nieuwland, M. S., & Meyer, A. S. (2023). Effects of picture naming and categorization on concurrent comprehension: Evidence from the N400. Collabra: Psychology, 9(1): 88129. doi:10.1525/collabra.88129.

    Abstract

    n conversations, interlocutors concurrently perform two related processes: speech comprehension and speech planning. We investigated effects of speech planning on comprehension using EEG. Dutch speakers listened to sentences that ended with expected or unexpected target words. In addition, a picture was presented two seconds after target onset (Experiment 1) or 50 ms before target onset (Experiment 2). Participants’ task was to name the picture or to stay quiet depending on the picture category. In Experiment 1, we found a strong N400 effect in response to unexpected compared to expected target words. Importantly, this N400 effect was reduced in Experiment 2 compared to Experiment 1. Unexpectedly, the N400 effect was not smaller in the naming compared to categorization condition. This indicates that conceptual preparation or the decision whether to speak (taking place in both task conditions of Experiment 2) rather than processes specific to word planning interfere with comprehension.
  • Hwang, S.-O., Tomita, N., Morgan, H., Ergin, R., İlkbaşaran, D., Seegers, S., Lepic, R., & Padden, C. (2016). Of the body and the hands: patterned iconicity for semantic categories. Language and Cognition, 9(4), 573-602. doi:10.1017/langcog.2016.28.

    Abstract

    This paper examines how gesturers and signers use their bodies to express concepts such as instrumentality and humanness. Comparing across eight sign languages (American, Japanese, German, Israeli, and Kenyan Sign Languages, Ha Noi Sign Language of Vietnam, Central Taurus Sign Language of Turkey, and Al-Sayyid Bedouin Sign Language of Israel) and the gestures of American non-signers, we find recurring patterns for naming entities in three semantic categories (tools, animals, and fruits & vegetables). These recurring patterns are captured in a classification system that identifies iconic strategies based on how the body is used together with the hands. Across all groups, tools are named with manipulation forms, where the head and torso represent those of a human agent. Animals tend to be identified with personification forms, where the body serves as a map for a comparable non-human body. Fruits & vegetables tend to be identified with object forms, where the hands act independently from the rest of the body to represent static features of the referent. We argue that these iconic patterns are rooted in using the body for communication, and provide a basis for understanding how meaningful communication emerges quickly in gesture and persists in emergent and established sign languages.
  • Iliadis, S. I., Sylvén, S., Hellgren, C., Olivier, J. D., Schijven, D., Comasco, E., Chrousos, G. P., Sundström Poromaa, I., & Skalkidou, A. (2016). Mid-pregnancy corticotropin-releasing hormone levels in association with postpartum depressive symptoms. Depression and Anxiety, 33(11), 1023-1030. doi:10.1002/da.22529.

    Abstract

    Background Peripartum depression is a common cause of pregnancy- and postpartum-related morbidity. The production of corticotropin-releasing hormone (CRH) from the placenta alters the profile of hypothalamus–pituitary–adrenal axis hormones and may be associated with postpartum depression. The purpose of this study was to assess, in nondepressed pregnant women, the possible association between CRH levels in pregnancy and depressive symptoms postpartum. Methods A questionnaire containing demographic data and the Edinburgh Postnatal Depression Scale (EPDS) was filled in gestational weeks 17 and 32, and 6 week postpartum. Blood samples were collected in week 17 for assessment of CRH. A logistic regression model was constructed, using postpartum EPDS score as the dependent variable and log-transformed CRH levels as the independent variable. Confounding factors were included in the model. Subanalyses after exclusion of study subjects with preterm birth, newborns small for gestational age (SGA), and women on corticosteroids were performed. Results Five hundred thirty-five women without depressive symptoms during pregnancy were included. Logistic regression showed an association between high CRH levels in gestational week 17 and postpartum depressive symptoms, before and after controlling for several confounders (unadjusted OR = 1.11, 95% CI 1.01–1.22; adjusted OR = 1.13, 95% CI 1.02–1.26; per 0.1 unit increase in log CRH). Exclusion of women with preterm birth and newborns SGA as well as women who used inhalation corticosteroids during pregnancy did not alter the results. Conclusions This study suggests an association between high CRH levels in gestational week 17 and the development of postpartum depressive symptoms, among women without depressive symptoms during pregnancy.
  • Indefrey, P., & Levelt, W. J. M. (1999). A meta-analysis of neuroimaging experiments on word production. Neuroimage, 7, 1028.
  • Indefrey, P., Kleinschmidt, A., Merboldt, K.-D., Krüger, G., Brown, C. M., Hagoort, P., & Frahm, J. (1997). Equivalent responses to lexical and nonlexical visual stimuli in occipital cortex: a functional magnetic resonance imaging study. Neuroimage, 5, 78-81. doi:10.1006/nimg.1996.0232.

    Abstract

    Stimulus-related changes in cerebral blood oxygenation were measured using high-resolution functional magnetic resonance imaging sequentially covering visual occipital areas in contiguous sections. During dynamic imaging, healthy subjects silently viewed pseudowords, single false fonts, or length-matched strings of the same false fonts. The paradigm consisted of a sixfold alternation of an activation and a control task. With pseudowords as activation vs single false fonts as control, responses were seen mainly in medial occipital cortex. These responses disappeared when pseudowords were alternated with false font strings as the control and reappeared when false font strings instead of pseudowords served as activation and were alternated with single false fonts. The string-length contrast alone, therefore, is sufficient to account for the activation pattern observed in medial visual cortex when word-like stimuli are contrasted with single characters.
  • Indefrey, P. (1998). De neurale architectuur van taal: Welke hersengebieden zijn betrokken bij het spreken. Neuropraxis, 2(6), 230-237.
  • Indefrey, P., Gruber, O., Brown, C. M., Hagoort, P., Posse, S., & Kleinschmidt, A. (1998). Lexicality and not syllable frequency determine lateralized premotor activation during the pronunciation of word-like stimuli: An fMRI study. NeuroImage, 7, S4.
  • Indefrey, P. (2016). On putative shortcomings and dangerous future avenues: response to Strijkers & Costa. Language, Cognition and Neuroscience, 31(4), 517-520. doi:10.1080/23273798.2015.1128554.
  • Indefrey, P. (1999). Some problems with the lexical status of nondefault inflection. Behavioral and Brain Sciences, 22(6), 1025. doi:10.1017/S0140525X99342229.

    Abstract

    Clahsen's characterization of nondefault inflection as based exclusively on lexical entries does not capture the full range of empirical data on German inflection. In the verb system differential effects of lexical frequency seem to be input-related rather than affecting morphological production. In the noun system, the generalization properties of -n and -e plurals exceed mere analogy-based productivity.
  • Ito, A., Corley, M., Pickering, M. J., Martin, A. E., & Nieuwland, M. S. (2016). Predicting form and meaning: Evidence from brain potentials. Journal of Memory and Language, 86, 157-171. doi:10.1016/j.jml.2015.10.007.

    Abstract

    We used ERPs to investigate the pre-activation of form and meaning in language comprehension. Participants read high-cloze sentence contexts (e.g., “The student is going to the library to borrow a…”), followed by a word that was predictable (book), form-related (hook) or semantically related (page) to the predictable word, or unrelated (sofa). At a 500 ms SOA (Experiment 1), semantically related words, but not form-related words, elicited a reduced N400 compared to unrelated words. At a 700 ms SOA (Experiment 2), semantically related words and form-related words elicited reduced N400 effects, but the effect for form-related words occurred in very high-cloze sentences only. At both SOAs, form-related words elicited an enhanced, post-N400 posterior positivity (Late Positive Component effect). The N400 effects suggest that readers can pre-activate meaning and form information for highly predictable words, but form pre-activation is more limited than meaning pre-activation. The post-N400 LPC effect suggests that participants detected the form similarity between expected and encountered input. Pre-activation of word forms crucially depends upon the time that readers have to make predictions, in line with production-based accounts of linguistic prediction.
  • Jadoul, Y., & Ravignani, A. (2023). Modelling the emergence of synchrony from decentralized rhythmic interactions in animal communication. Proceedings of the Royal Society B: Biological Sciences, 290(2003). doi:10.1098/rspb.2023.0876.

    Abstract

    To communicate, an animal's strategic timing of rhythmic signals is crucial. Evolutionary, game-theoretical, and dynamical systems models can shed light on the interaction between individuals and the associated costs and benefits of signalling at a specific time. Mathematical models that study rhythmic interactions from a strategic or evolutionary perspective are rare in animal communication research. But new inspiration may come from a recent game theory model of how group synchrony emerges from local interactions of oscillatory neurons. In the study, the authors analyse when the benefit of joint synchronization outweighs the cost of individual neurons sending electrical signals to each other. They postulate there is a benefit for pairs of neurons to fire together and a cost for a neuron to communicate. The resulting model delivers a variant of a classical dynamical system, the Kuramoto model. Here, we present an accessible overview of the Kuramoto model and evolutionary game theory, and of the 'oscillatory neurons' model. We interpret the model's results and discuss the advantages and limitations of using this particular model in the context of animal rhythmic communication. Finally, we sketch potential future directions and discuss the need to further combine evolutionary dynamics, game theory and rhythmic processes in animal communication studies.
  • Jadoul, Y., Düngen, D., & Ravignani, A. (2023). PyGellermann: a Python tool to generate pseudorandom series for human and non-human animal behavioural experiments. BMC Research Notes, 16: 135. doi:10.1186/s13104-023-06396-x.

    Abstract

    Objective

    Researchers in animal cognition, psychophysics, and experimental psychology need to randomise the presentation order of trials in experimental sessions. In many paradigms, for each trial, one of two responses can be correct, and the trials need to be ordered such that the participant’s responses are a fair assessment of their performance. Specifically, in some cases, especially for low numbers of trials, randomised trial orders need to be excluded if they contain simple patterns which a participant could accidentally match and so succeed at the task without learning.
    Results

    We present and distribute a simple Python software package and tool to produce pseudorandom sequences following the Gellermann series. This series has been proposed to pre-empt simple heuristics and avoid inflated performance rates via false positive responses. Our tool allows users to choose the sequence length and outputs a .csv file with newly and randomly generated sequences. This allows behavioural researchers to produce, in a few seconds, a pseudorandom sequence for their specific experiment. PyGellermann is available at https://github.com/YannickJadoul/PyGellermann.
  • Jadoul, Y., De Boer, B., & Ravignani, A. (2024). Parselmouth for bioacoustics: Automated acoustic analysis in Python. Bioacoustics, 33(1), 1-19. doi:10.1080/09524622.2023.2259327.

    Abstract

    Bioacoustics increasingly relies on large datasets and computational methods. The need to batch-process large amounts of data and the increased focus on algorithmic processing require software tools. To optimally assist in a bioacoustician’s workflow, software tools need to be as simple and effective as possible. Five years ago, the Python package Parselmouth was released to provide easy and intuitive access to all functionality in the Praat software. Whereas Praat is principally designed for phonetics and speech processing, plenty of bioacoustics studies have used its advanced acoustic algorithms. Here, we evaluate existing usage of Parselmouth and discuss in detail several studies which used the software library. We argue that Parselmouth has the potential to be used even more in bioacoustics research, and suggest future directions to be pursued with the help of Parselmouth.
  • Jago, L. S., Alcock, K., Meints, K., Pine, J. M., & Rowland, C. F. (2023). Language outcomes from the UK-CDI Project: Can risk factors, vocabulary skills and gesture scores in infancy predict later language disorders or concern for language development? Frontiers in Psychology, 14: 1167810. doi:10.3389/fpsyg.2023.1167810.

    Abstract

    At the group level, children exposed to certain health and demographic risk factors, and who have delayed language in early childhood are, more likely to have language problems later in childhood. However, it is unclear whether we can use these risk factors to predict whether an individual child is likely to develop problems with language (e.g., be diagnosed with a developmental language disorder). We tested this in a sample of 146 children who took part in the UK-CDI norming project. When the children were 15–18 months old, 1,210 British parents completed: (a) the UK-CDI (a detailed assessment of vocabulary and gesture use) and (b) the Family Questionnaire (questions about health and demographic risk factors). When the children were between 4 and 6  years, 146 of the same parents completed a short questionnaire that assessed (a) whether children had been diagnosed with a disability that was likely to affect language proficiency (e.g., developmental disability, language disorder, hearing impairment), but (b) also yielded a broader measure: whether the child’s language had raised any concern, either by a parent or professional. Discriminant function analyses were used to assess whether we could use different combinations of 10 risk factors, together with early vocabulary and gesture scores, to identify children (a) who had developed a language-related disability by the age of 4–6 years (20 children, 13.70% of the sample) or (b) for whom concern about language had been expressed (49 children; 33.56%). The overall accuracy of the models, and the specificity scores were high, indicating that the measures correctly identified those children without a language-related disability and whose language was not of concern. However, sensitivity scores were low, indicating that the models could not identify those children who were diagnosed with a language-related disability or whose language was of concern. Several exploratory analyses were carried out to analyse these results further. Overall, the results suggest that it is difficult to use parent reports of early risk factors and language in the first 2 years of life to predict which children are likely to be diagnosed with a language-related disability. Possible reasons for this are discussed.

    Additional information

    follow up questionnaire table S1
  • Janssen, R., Nolfi, S., Haselager, W. F. G., & Sprinkhuizen-Kuyper, I. G. (2016). Cyclic Incrementality in Competitive Coevolution: Evolvability through Pseudo-Baldwinian Switching-Genes. Artificial Life, 22(3), 319-352. doi:10.1162/ARTL_a_00208.

    Abstract

    Coevolving systems are notoriously difficult to understand. This is largely due to the Red Queen effect that dictates heterospecific fitness interdependence. In simulation studies of coevolving systems, master tournaments are often used to obtain more informed fitness measures by testing evolved individuals against past and future opponents. However, such tournaments still contain certain ambiguities. We introduce the use of a phenotypic cluster analysis to examine the distribution of opponent categories throughout an evolutionary sequence. This analysis, adopted from widespread usage in the bioinformatics community, can be applied to master tournament data. This allows us to construct behavior-based category trees, obtaining a hierarchical classification of phenotypes that are suspected to interleave during cyclic evolution. We use the cluster data to establish the existence of switching-genes that control opponent specialization, suggesting the retention of dormant genetic adaptations, that is, genetic memory. Our overarching goal is to reiterate how computer simulations may have importance to the broader understanding of evolutionary dynamics in general. We emphasize a further shift from a component-driven to an interaction-driven perspective in understanding coevolving systems. As yet, it is unclear how the sudden development of switching-genes relates to the gradual emergence of genetic adaptability. Likely, context genes gradually provide the appropriate genetic environment wherein the switching-gene effect can be exploited
  • Jaspers, D., & Seuren, P. A. M. (2016). The Square of opposition in catholic hands: A chapter in the history of 20th-century logic. Logique et Analyse, 59(233), 1-35.

    Abstract

    The present study describes how three now almost forgotten mid-20th-century logicians, the American Paul Jacoby and the Frenchmen Augustin Sesmat and Robert Blanché, all three ardent Catholics, tried to restore traditional predicate logic to a position of respectability by expanding the classic Square of Opposition to a hexagon of logical relations, showing the logical and cognitive advantages of such an expansion. The nature of these advantages is discussed in the context of modern research regarding the relations between logic, language, and cognition. It is desirable to call attention to these attempts, as they are, though almost totally forgotten, highly relevant against the backdrop of the clash between modern and traditional logic. It is argued that this clash was and is unnecessary, as both forms of predicate logic are legitimate, each in its own right. The attempts by Jacoby, Sesmat, and Blanché are, moreover, of interest to the history of logic in a cultural context in that, in their own idiosyncratic ways, they fit into the general pattern of the Catholic cultural revival that took place roughly between the years 1840 and 1960. The Catholic Church had put up stiff resistance to modern mathematical logic, considering it dehumanizing and a threat to Catholic doctrine. Both the wider cultural context and the specific implications for logic are described and analyzed, in conjunction with the more general philosophical and doctrinal issues involved.
  • Jiang, T., Zhang, W., Wen, W., Zhu, H., Du, H., Zhu, X., Gao, X., Zhang, H., Dong, Q., & Chen, C. (2016). Reevaluating the two-representation model of numerical magnitude processing. Memory & Cognition, 44, 162-170. doi:10.3758/s13421-015-0542-2.

    Abstract

    One debate in mathematical cognition centers on the single-representation model versus the two-representation model. Using an improved number Stroop paradigm (i.e., systematically manipulating physical size distance), in the present study we tested the predictions of the two models for number magnitude processing. The results supported the single-representation model and, more importantly, explained how a design problem (failure to manipulate physical size distance) and an analytical problem (failure to consider the interaction between congruity and task-irrelevant numerical distance) might have contributed to the evidence used to support the two-representation model. This study, therefore, can help settle the debate between the single-representation and two-representation models. © 2015 The Author(s)
  • Jin, H., Wang, Q., Yang, Y.-F., Zhang, H., Gao, M. (., Jin, S., Chen, Y. (., Xu, T., Zheng, Y.-R., Chen, J., Xiao, Q., Yang, J., Wang, X., Geng, H., Ge, J., Wang, W.-W., Chen, X., Zhang, L., Zuo, X.-N., & Chuan-Peng, H. (2023). The Chinese Open Science Network (COSN): Building an open science community from scratch. Advances in Methods and Practices in Psychological Science, 6(1): 10.1177/25152459221144986. doi:10.1177/25152459221144986.

    Abstract

    Open Science is becoming a mainstream scientific ideology in psychology and related fields. However, researchers, especially early-career researchers (ECRs) in developing countries, are facing significant hurdles in engaging in Open Science and moving it forward. In China, various societal and cultural factors discourage ECRs from participating in Open Science, such as the lack of dedicated communication channels and the norm of modesty. To make the voice of Open Science heard by Chinese-speaking ECRs and scholars at large, the Chinese Open Science Network (COSN) was initiated in 2016. With its core values being grassroots-oriented, diversity, and inclusivity, COSN has grown from a small Open Science interest group to a recognized network both in the Chinese-speaking research community and the international Open Science community. So far, COSN has organized three in-person workshops, 12 tutorials, 48 talks, and 55 journal club sessions and translated 15 Open Science-related articles and blogs from English to Chinese. Currently, the main social media account of COSN (i.e., the WeChat Official Account) has more than 23,000 subscribers, and more than 1,000 researchers/students actively participate in the discussions on Open Science. In this article, we share our experience in building such a network to encourage ECRs in developing countries to start their own Open Science initiatives and engage in the global Open Science movement. We foresee great collaborative efforts of COSN together with all other local and international networks to further accelerate the Open Science movement.
  • Jodzio, A., Piai, V., Verhagen, L., Cameron, I., & Indefrey, P. (2023). Validity of chronometric TMS for probing the time-course of word production: A modified replication. Cerebral Cortex, 33(12), 7816-7829. doi:10.1093/cercor/bhad081.

    Abstract

    In the present study, we used chronometric TMS to probe the time-course of 3 brain regions during a picture naming task. The left inferior frontal gyrus, left posterior middle temporal gyrus, and left posterior superior temporal gyrus were all separately stimulated in 1 of 5 time-windows (225, 300, 375, 450, and 525 ms) from picture onset. We found posterior temporal areas to be causally involved in picture naming in earlier time-windows, whereas all 3 regions appear to be involved in the later time-windows. However, chronometric TMS produces nonspecific effects that may impact behavior, and furthermore, the time-course of any given process is a product of both the involved processing stages along with individual variation in the duration of each stage. We therefore extend previous work in the field by accounting for both individual variations in naming latencies and directly testing for nonspecific effects of TMS. Our findings reveal that both factors influence behavioral outcomes at the group level, underlining the importance of accounting for individual variations in naming latencies, especially for late processing stages closer to articulation, and recognizing the presence of nonspecific effects of TMS. The paper advances key considerations and avenues for future work using chronometric TMS to study overt production.
  • Jordanoska, I., Kocher, A., & Bendezú-Araujo, R. (2023). Introduction special issue: Marking the truth: A cross-linguistic approach to verum. Zeitschrift für Sprachwissenschaft, 42(3), 429-442. doi:10.1515/zfs-2023-2012.

    Abstract

    This special issue focuses on the theoretical and empirical underpinnings of truth-marking. The names that have been used to refer to this phenomenon include, among others, counter-assertive focus, polar(ity) focus, verum focus, emphatic polarity or simply verum. This terminological variety is suggestive of the wide range of ideas and conceptions that characterizes this research field. This collection aims to get closer to the core of what truly constitutes verum. We want to expand the empirical base and determine the common and diverging properties of truth-marking in the languages of the world. The objective is to set a theoretical and empirical baseline for future research on verum and related phenomena.
  • Jordanoska, I., Kocher, A., & Bendezú-Araujo, R. (Eds.). (2023). Marking the truth: A cross-linguistic approach to verum [Special Issue]. Zeitschrift für Sprachwissenschaft, 42(3).
  • Jordens, P. (1997). Introducing the basic variety. Second Language Research, 13(4), 289-300. doi:10.1191%2F026765897672176425.
  • Kakimoto, N., Wongratwanich, P., Shimamoto, H., Kitisubkanchana, J., Tsujimoto, T., Shimabukuro, K., Verdonschot, R. G., Hasegawa, Y., & Murakami, S. (2024). Comparison of T2 values of the displaced unilateral disc and retrodiscal tissue of temporomandibular joints and their implications. Scientific Reports, 14: 1705. doi:10.1038/s41598-024-52092-6.

    Abstract

    Unilateral anterior disc displacement (uADD) has been shown to affect the contralateral joints qualitatively. This study aims to assess the quantitative T2 values of the articular disc and retrodiscal tissue of patients with uADD at 1.5 Tesla (T). The study included 65 uADD patients and 17 volunteers. The regions of interest on T2 maps were evaluated. The affected joints demonstrated significantly higher articular disc T2 values (31.5 ± 3.8 ms) than those of the unaffected joints (28.9 ± 4.5 ms) (P < 0.001). For retrodiscal tissue, T2 values of the unaffected (37.8 ± 5.8 ms) and affected joints (41.6 ± 7.1 ms) were significantly longer than those of normal volunteers (34.4 ± 3.2 ms) (P < 0.001). Furthermore, uADD without reduction (WOR) joints (43.3 ± 6.8 ms) showed statistically higher T2 values than the unaffected joints of both uADD with reduction (WR) (33.9 ± 3.8 ms) and uADDWOR (38.9 ± 5.8 ms), and the affected joints of uADDWR (35.8 ± 4.4 ms). The mean T2 value of the unaffected joints of uADDWOR was significantly longer than that of healthy volunteers (P < 0.001). These results provided quantitative evidence for the influence of the affected joints on the contralateral joints.
  • Kałamała, P., Chuderski, A., Szewczyk, J., Senderecka, M., & Wodniecka, Z. (2023). Bilingualism caught in a net: A new approach to understanding the complexity of bilingual experience. Journal of Experimental Psychology: General, 152(1), 157-174. doi:10.1037/xge0001263.

    Abstract

    The growing importance of research on bilingualism in psychology and neuroscience motivates the need for a psychometric model that can be used to understand and quantify this phenomenon. This research is the first to meet this need. We reanalyzed two data sets (N = 171 and N = 112) from relatively young adult language-unbalanced bilinguals and asked whether bilingualism is best described by the factor structure or by the network structure. The factor and network models were established on one data set and then validated on the other data set in a fully confirmatory manner. The network model provided the best fit to the data. This implies that bilingualism should be conceptualized as an emergent phenomenon arising from direct and idiosyncratic dependencies among the history of language acquisition, diverse language skills, and language-use practices. These dependencies can be reduced to neither a single universal quotient nor to some more general factors. Additional in-depth network analyses showed that the subjective perception of proficiency along with language entropy and language mixing were the most central indices of bilingualism, thus indicating that these measures can be especially sensitive to variation in the overall bilingual experience. Overall, this work highlights the great potential of psychometric network modeling to gain a more accurate description and understanding of complex (psycho)linguistic and cognitive phenomena.
  • Karaca, F., Brouwer, S., Unsworth, S., & Huettig, F. (2024). Morphosyntactic predictive processing in adult heritage speakers: Effects of cue availability and spoken and written language experience. Language, Cognition and Neuroscience, 39(1), 118-135. doi:10.1080/23273798.2023.2254424.

    Abstract

    We investigated prediction skills of adult heritage speakers and the role of written and spoken language experience on predictive processing. Using visual world eye-tracking, we focused on predictive use of case-marking cues in verb-medial and verb-final sentences in Turkish with adult Turkish heritage speakers (N = 25) and Turkish monolingual speakers (N = 24). Heritage speakers predicted in verb-medial sentences (when verb-semantic and case-marking cues were available), but not in verb-final sentences (when only case-marking cues were available) while monolinguals predicted in both. Prediction skills of heritage speakers were modulated by their spoken language experience in Turkish and written language experience in both languages. Overall, these results strongly suggest that verb-semantic information is needed to scaffold the use of morphosyntactic cues for prediction in heritage speakers. The findings also support the notion that both spoken and written language experience play an important role in predictive spoken language processing.
  • Karadöller, D. Z., Sumer, B., Ünal, E., & Özyürek, A. (2023). Late sign language exposure does not modulate the relation between spatial language and spatial memory in deaf children and adults. Memory & Cognition, 51, 582-600. doi:10.3758/s13421-022-01281-7.

    Abstract

    Prior work with hearing children acquiring a spoken language as their first language shows that spatial language and cognition are related systems and spatial language use predicts spatial memory. Here, we further investigate the extent of this relationship in signing deaf children and adults and ask if late sign language exposure, as well as the frequency and the type of spatial language use that might be affected by late exposure, modulate subsequent memory for spatial relations. To do so, we compared spatial language and memory of 8-year-old late-signing children (after 2 years of exposure to a sign language at the school for the deaf) and late-signing adults to their native-signing counterparts. We elicited picture descriptions of Left-Right relations in Turkish Sign Language (Türk İşaret Dili) and measured the subsequent recognition memory accuracy of the described pictures. Results showed that late-signing adults and children were similar to their native-signing counterparts in how often they encoded the spatial relation. However, late-signing adults but not children differed from their native-signing counterparts in the type of spatial language they used. However, neither late sign language exposure nor the frequency and type of spatial language use modulated spatial memory accuracy. Therefore, even though late language exposure seems to influence the type of spatial language use, this does not predict subsequent memory for spatial relations. We discuss the implications of these findings based on the theories concerning the correspondence between spatial language and cognition as related or rather independent systems.
  • Karadöller, D. Z., Peeters, D., Manhardt, F., Özyürek, A., & Ortega, G. (2024). Iconicity and gesture jointly facilitate learning of second language signs at first exposure in hearing non-signers. Language Learning. Advance online publication. doi:10.1111/lang.12636.

    Abstract

    When learning a spoken second language (L2), words overlapping in form and meaning with one’s native language (L1) help break into the new language. When non-signing speakers learn a sign language as L2, such forms are absent because of the modality differences (L1:speech, L2:sign). In such cases, non-signing speakers might use iconic form-meaning mappings in signs or their own gestural experience as gateways into the to-be-acquired sign language. Here, we investigated how both these factors may contribute jointly to the acquisition of sign language vocabulary by hearing non-signers. Participants were presented with three types of sign in NGT (Sign Language of the Netherlands): arbitrary signs, iconic signs with high or low gesture overlap. Signs that were both iconic and highly overlapping with gestures boosted learning most at first exposure, and this effect remained the day after. Findings highlight the influence of modality-specific factors supporting the acquisition of a signed lexicon.
  • Karsan, Ç., Ocak, F., & Bulut, T. (2024). Characterization of speech and language phenotype in the 8p23.1 syndrome. European Child & Adolescent Psychiatry. Advance online publication. doi:10.1007/s00787-024-02448-0.

    Abstract

    The 8p23.1 duplication syndrome is a rare genetic condition with an estimated prevalence rate of 1 out of 58,000. Although the syndrome was associated with speech and language delays, a comprehensive assessment of speech and language functions has not been undertaken in this population. To address this issue, the present study reports rigorous speech and language, in addition to oral-facial and developmental, assessment of a 50-month-old Turkish-speaking boy who was diagnosed with the 8p23.1 duplication syndrome. Standardized tests of development, articulation and phonology, receptive and expressive language and a language sample analysis were administered to characterize speech and language skills in the patient. The language sample was obtained in an ecologically valid, free play and conversation context. The language sample was then analyzed and compared to a database of age-matched typically-developing children (n = 33) in terms of intelligibility, morphosyntax, semantics/vocabulary, discourse, verbal facility and percentage of errors at word and utterance levels. The results revealed mild to severe problems in articulation and phonology, receptive and expressive language skills, and morphosyntax (mean length of utterance in morphemes). Future research with larger sample sizes and employing detailed speech and language assessment is needed to delineate the speech and language profile in individuals with the 8p23.1 duplication syndrome, which will guide targeted speech and language interventions.
  • Kartushina, N., Hervais-Adelman, A., Frauenfelder, U. H., & Golestani, N. (2016). Mutual influences between native and non-native vowels in production: Evidence from short-term visual articulatory feedback training. Journal of Phonetics, 57, 21-39. doi:10.1016/j.wocn.2016.05.001.

    Abstract

    We studied mutual influences between native and non-native vowel production during learning, i.e., before and after short-term visual articulatory feedback training with non-native sounds. Monolingual French speakers were trained to produce two non-native vowels: the Danish /ɔ/, which is similar to the French /o/, and the Russian /ɨ/, which is dissimilar from French vowels. We examined relationships between the production of French and non-native vowels before training, and the effects of training with non-native vowels on the production of French ones. We assessed for each participant the acoustic position and compactness of the trained vowels, and of the French /o/, /ø/, /y/ and /i/ vowels, which are acoustically closest to the trained vowels. Before training, the compactness of the French vowels was positively related to the accuracy and compactness in the production of non-native vowels. After training, French speakers’ accuracy and stability in the production of the two trained vowels improved on average by 19% and 37.5%, respectively. Interestingly, the production of native vowels was also affected by this learning process, with a drift towards non-native vowels. The amount of phonetic drift appears to depend on the degree of similarity between the native and non-native sounds.
  • Kaspi, A., Hildebrand, M. S., Jackson, V. E., Braden, R., Van Reyk, O., Howell, T., Debono, S., Lauretta, M., Morison, L., Coleman, M. J., Webster, R., Coman, D., Goel, H., Wallis, M., Dabscheck, G., Downie, L., Baker, E. K., Parry-Fielder, B., Ballard, K., Harrold, E. and 10 moreKaspi, A., Hildebrand, M. S., Jackson, V. E., Braden, R., Van Reyk, O., Howell, T., Debono, S., Lauretta, M., Morison, L., Coleman, M. J., Webster, R., Coman, D., Goel, H., Wallis, M., Dabscheck, G., Downie, L., Baker, E. K., Parry-Fielder, B., Ballard, K., Harrold, E., Ziegenfusz, S., Bennett, M. F., Robertson, E., Wang, L., Boys, A., Fisher, S. E., Amor, D. J., Scheffer, I. E., Bahlo, M., & Morgan, A. T. (2023). Genetic aetiologies for childhood speech disorder: Novel pathways co-expressed during brain development. Molecular Psychiatry, 28, 1647-1663. doi:10.1038/s41380-022-01764-8.

    Abstract

    Childhood apraxia of speech (CAS), the prototypic severe childhood speech disorder, is characterized by motor programming and planning deficits. Genetic factors make substantive contributions to CAS aetiology, with a monogenic pathogenic variant identified in a third of cases, implicating around 20 single genes to date. Here we aimed to identify molecular causation in 70 unrelated probands ascertained with CAS. We performed trio genome sequencing. Our bioinformatic analysis examined single nucleotide, indel, copy number, structural and short tandem repeat variants. We prioritised appropriate variants arising de novo or inherited that were expected to be damaging based on in silico predictions. We identified high confidence variants in 18/70 (26%) probands, almost doubling the current number of candidate genes for CAS. Three of the 18 variants affected SETBP1, SETD1A and DDX3X, thus confirming their roles in CAS, while the remaining 15 occurred in genes not previously associated with this disorder. Fifteen variants arose de novo and three were inherited. We provide further novel insights into the biology of child speech disorder, highlighting the roles of chromatin organization and gene regulation in CAS, and confirm that genes involved in CAS are co-expressed during brain development. Our findings confirm a diagnostic yield comparable to, or even higher, than other neurodevelopmental disorders with substantial de novo variant burden. Data also support the increasingly recognised overlaps between genes conferring risk for a range of neurodevelopmental disorders. Understanding the aetiological basis of CAS is critical to end the diagnostic odyssey and ensure affected individuals are poised for precision medicine trials.
  • Kavaklioglu, T., Ajmal, M., Hameed, A., & Francks, C. (2016). Whole exome sequencing for handedness in a large and highly consanguineous family. Neuropsychologia, 93, part B, 342-349. doi:10.1016/j.neuropsychologia.2015.11.010.

    Abstract

    Pinpointing genes involved in non-right-handedness has the potential to clarify developmental contributions to human brain lateralization. Major-gene models have been considered for human handedness which allow for phenocopy and reduced penetrance, i.e. an imperfect correspondence between genotype and phenotype. However, a recent genome-wide association scan did not detect any common polymorphisms with substantial genetic effects. Previous linkage studies in families have also not yielded significant findings. Genetic heterogeneity and/or polygenicity are therefore indicated, but it remains possible that relatively rare, or even unique, major-genetic effects may be detectable in certain extended families with many non-right-handed members. Here we applied whole exome sequencing to 17 members from a single, large consanguineous family from Pakistan. Multipoint linkage analysis across all autosomes did not yield clear candidate genomic regions for involvement in the trait and single-point analysis of exomic variation did not yield clear candidate mutations/genes. Any genetic contribution to handedness in this unusual family is therefore likely to have a complex etiology, as at the population level.
  • Kempen, G., Anbeek, G., Desain, P., Konst, L., & De Smedt, K. (1987). Auteursomgevingen: Vijfde-generatie tekstverwerkers. Informatie, 29, 988-993.
  • Kempen, G. (1991). Conjunction reduction and gapping in clause-level coordination: An inheritance-based approach. Computational Intelligence, 7, 357-360. doi:10.1111/j.1467-8640.1991.tb00406.x.
  • Kempen, G. (1998). Comparing and explaining the trajectories of first and second language acquisition: In search of the right mix of psychological and linguistic factors [Commentory]. Bilingualism: Language and Cognition, 1, 29-30. doi:10.1017/S1366728998000066.

    Abstract

    When you compare the behavior of two different age groups which are trying to master the same sensori-motor or cognitive skill, you are likely to discover varying learning routes: different stages, different intervals between stages, or even different orderings of stages. Such heterogeneous learning trajectories may be caused by at least six different types of factors: (1) Initial state: the kinds and levels of skills the learners have available at the onset of the learning episode. (2) Learning mechanisms: rule-based, inductive, connectionist, parameter setting, and so on. (3) Input and feedback characteristics: learning stimuli, information about success and failure. (4) Information processing mechanisms: capacity limitations, attentional biases, response preferences. (5) Energetic variables: motivation, emotional reactions. (6) Final state: the fine-structure of kinds and levels of subskills at the end of the learning episode. This applies to language acquisition as well. First and second language learners probably differ on all six factors. Nevertheless, the debate between advocates and opponents of the Fundamental Difference Hypothesis concerning L1 and L2 acquisition have looked almost exclusively at the first two factors. Those who believe that L1 learners have access to Universal Grammar whereas L2 learners rely on language processing strategies, postulate different learning mechanisms (UG parameter setting in L1, more general inductive strategies in L2 learning). Pienemann opposes this view and, based on his Processability Theory, argues that L1 and L2 learners start out from different initial states: they come to the grammar learning task with different structural hypotheses (SOV versus SVO as basic word order of German).
  • Kempen, G., & Hoenkamp, E. (1987). An incremental procedural grammar for sentence formulation. Cognitive Science, 11(2), 201-258.

    Abstract

    This paper presents a theory of the syntactic aspects of human sentence production. An important characteristic of unprepared speech is that overt pronunciation of a sentence can be initiated before the speaker has completely worked out the meaning content he or she is going to express in that sentence. Apparently, the speaker is able to build up a syntactically coherent utterance out of a series of syntactic fragments each rendering a new part of the meaning content. This incremental, left-to-right mode of sentence production is the central capability of the proposed Incremental Procedural Grammar (IPG). Certain other properties of spontaneous speech, as derivable from speech errors, hesitations, self-repairs, and language pathology, are accounted for as well. The psychological plausibility thus gained by the grammar appears compatible with a satisfactory level of linguistic plausibility in that sentences receive structural descriptions which are in line with current theories of grammar. More importantly, an explanation for the existence of configurational conditions on transformations and other linguistics rules is proposed. The basic design feature of IPG which gives rise to these psychologically and linguistically desirable properties, is the “Procedures + Stack” concept. Sentences are built not by a central constructing agency which overlooks the whole process but by a team of syntactic procedures (modules) which work-in parallel-on small parts of the sentence, have only a limited overview, and whose sole communication channel is a stock. IPG covers object complement constructions, interrogatives, and word order in main and subordinate clauses. It handles unbounded dependencies, cross-serial dependencies and coordination phenomena such as gapping and conjunction reduction. It is also capable of generating self-repairs and elliptical answers to questions. IPG has been implemented as an incremental Dutch sentence generator written in LISP.
  • Kempen, G., Schotel, H., & Hoenkamp, E. (1982). Analyse-door-synthese van Nederlandse zinnen [Abstract]. De Psycholoog, 17, 509.
  • Kempen, G., & Kolk, H. (1980). Apentaal, een kwestie van intelligentie, niet van taalaanleg. Cahiers Biowetenschappen en Maatschappij, 6, 31-36.
  • Kempen, G. (1999). Fiets en (centri)fuge. Onze Taal, 68, 88.
  • Kempen, G., & Van Wijk, C. (1980). Leren formuleren: Hoe uit opstellen een objektieve index voor formuleervaardigheid afgeleid kan worden. De Psycholoog, 15, 609-621.
  • Kempen, G. (1987). Tekstverwerking: De vijfde generatie. Informatie, 29, 402-406.
  • Kempen, G. (1988). Preface. Acta Psychologica, 69(3), 205-206. doi:10.1016/0001-6918(88)90032-7.
  • Kempen, G. (1997). Van taalbarrières naar linguïstische snelwegen: Inrichting van een technische taalinfrastructuur voor het Nederlands. Grenzen aan veeltaligheid: Taalgebruik en bestuurlijke doeltreffendheid in de instellingen van de Europese Unie, 43-48.
  • Kempen, G., & Harbusch, K. (2016). Verb-second word order after German weil ‘because’: psycholinguistic theory from corpus-linguistic data. Glossa: a journal of general linguistics, 1(1): 3. doi:10.5334/gjgl.46.

    Abstract

    In present-day spoken German, subordinate clauses introduced by the connector weil ‘because’ occur with two orders of subject, finite verb, and object(s). In addition to weil clauses with verb-final word order (“VF”; standard in subordinate clauses) one often hears weil clauses with SVO, the standard order of main clauses (“verb-second”, V2). The “weil-V2” phenomenon is restricted to sentences where the weil clause follows the main clause, and is virtually absent from formal (written, edited) German, occurring only in extemporaneous speech. Extant accounts of weil-V2 focus on the interpretation of weil-V2 clauses by the hearer, in particular on the type of discourse relation licensed by weil-V2 vs. weil-VF: causal/propositional or inferential/epistemic. Focusing instead on the production of weil clauses by the speaker, we examine a collection of about 1,000 sentences featuring a causal connector (weil, da or denn) after the main clause, all extracted from a corpus of spoken German dialogues and annotated with tags denoting major prosodic and syntactic boundaries, and various types of disfluencies (pauses, hesitations). Based on the observed frequency patterns and on known linguistic properties of the connectors, we propose that weil-V2 is caused by miscoordination between the mechanisms for lexical retrieval and grammatical encoding: Due to its high frequency, the lexical item weil is often selected prematurely, while the grammatical encoder is still working on the syntactic shape of the weil clause. Weil-V2 arises when pragmatic and processing factors drive the encoder to discontinue the current sentence, and to plan the clause following weil in the form of the main clause of an independent, new sentence. Thus, the speaker continues with a V2 clause, seemingly in violation of the VF constraint imposed by the preceding weil. We also explore implications of the model regarding the interpretation of sentences containing causal connectors.
  • Kendrick, K. H., & Drew, P. (2016). Recruitment: Offers, requests, and the organization of assistance in interaction. Research on Language and Social Interaction, 49(1), 1-19. doi:10.1080/08351813.2016.1126436.

    Abstract

    In this article, we examine methods that participants use to resolve troubles in the realization of practical courses of action. The concept of recruitment is developed to encompass the linguistic and embodied ways in which assistance may be sought – requested or solicited – or in which we come to perceive another’s need and offer or volunteer assistance. We argue that these methods are organized as a continuum, from explicit requests, to practices that elicit offers, to anticipations of need. We further identify a class of subsidiary actions that can precede recruitment and that publicly expose troubles and thereby create opportunities for others to assist. Data in American and British English.
  • Kendrick, K. H., & Drew, P. (2016). The boundary of recruitment: A response. Research on Language and Social Interaction, 49, 32-33. doi:10.1080/08351813.2016.1126442.

    Abstract

    In their commentaries, both Heritage (2016/this issue) and Zinken and Rossi (2016/this issue) provide some context for our concept of and approach to recruitment in terms of previous research into requesting and offering. In doing so, they usefully consider what might be the boundaries of recruitmentwhat might be included and what might not be included or treated as recruitment. We respond here to their suggestions concerning these boundaries.
  • Kendrick, K. H., Holler, J., & Levinson, S. C. (2023). Turn-taking in human face-to-face interaction is multimodal: Gaze direction and manual gestures aid the coordination of turn transitions. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 378(1875): 20210473. doi:10.1098/rstb.2021.0473.

    Abstract

    Human communicative interaction is characterized by rapid and precise turn-taking. This is achieved by an intricate system that has been elucidated in the field of conversation analysis, based largely on the study of the auditory signal. This model suggests that transitions occur at points of possible completion identified in terms of linguistic units. Despite this, considerable evidence exists that visible bodily actions including gaze and gestures also play a role. To reconcile disparate models and observations in the literature, we combine qualitative and quantitative methods to analyse turn-taking in a corpus of multimodal interaction using eye-trackers and multiple cameras. We show that transitions seem to be inhibited when a speaker averts their gaze at a point of possible turn completion, or when a speaker produces gestures which are beginning or unfinished at such points. We further show that while the direction of a speaker's gaze does not affect the speed of transitions, the production of manual gestures does: turns with gestures have faster transitions. Our findings suggest that the coordination of transitions involves not only linguistic resources but also visual gestural ones and that the transition-relevance places in turns are multimodal in nature.

    Additional information

    supplemental material
  • Kent, A., & Kendrick, K. H. (2016). Imperative directives: Orientations to accountability. Research on Language and Social Interaction, 49(3), 272-288. doi:10.1080/08351813.2016.1201737.

    Abstract

    Our analysis proceeds from the question that if grammar alone is insuffi- cient to identify the action of an imperative (e.g., offering, directing, warn- ing, begging, etc.), how can interlocutors come to recognize the specific action being performed by a given imperative? We argue that imperative directives that occur after the directed action could have first been rele- vantly performed explicitly to direct the actions of the recipient and tacitly treat the absence of the action as a failure for which the recipient is accountable. The tacit nature of the accountability orientation enables both parties to focus on restoring progressivity to the directed course of action rather than topicalizing a transgression. Data are from everyday interactions in British and American English.
  • Kholodova, A., Peter, M., Rowland, C. F., Jacob, G., & Allen, S. E. M. (2023). Abstract priming and the lexical boost effect across development in a structurally biased language. Languages, 8: 264. doi:10.3390/languages8040264.

    Abstract

    The present study investigates the developmental trajectory of abstract representations for syntactic structures in children. In a structural priming experiment on the dative alternation in German, we primed children from three different age groups (3–4 years, 5–6 years, 7–8 years) and adults with double object datives (Dora sent Boots the rabbit) or prepositional object datives (Dora sent the rabbit to Boots). Importantly, the prepositional object structure in German is dispreferred and only rarely encountered by young children. While immediate as well as cumulative structural priming effects occurred across all age groups, these effects were strongest in the 3- to 4-year-old group and gradually decreased with increasing age. These results suggest that representations in young children are less stable than in adults and, therefore, more susceptible to adaptation both immediately and across time, presumably due to stronger surprisal. Lexical boost effects, in contrast, were not present in 3- to 4-year-olds but gradually emerged with increasing age, possibly due to limited working-memory capacity in the younger child groups.
  • Kidd, E., Arciuli, J., Christiansen, M. H., & Smithson, M. (2023). The sources and consequences of individual differences in statistical learning for language development. Cognitive Development, 66: 101335. doi:10.1016/j.cogdev.2023.101335.

    Abstract

    Statistical learning (SL)—sensitivity to statistical regularities in the environment—has been postulated to support language development. While even young infants are capable of using distributional statistics to learn in linguistic and non-linguistic domains, efforts to measure SL at the level of the individual and link it to language proficiency in individual differences designs have been mixed, which has at least in part been attributed to problems with task reliability. In the current study we present the first prospective longitudinal study of the relationship between both non-linguistic SL (measured with visual stimuli) and linguistic SL (measured with auditory stimuli) and language in a group of English-speaking children. One-hundred and twenty-one (N = 121) children in their first two years of formal schooling (Mage = 6;1 years, Range: 5;2 – 7;2) completed tests of visual SL (VSL) and auditory SL (ASL) and several control variables at time 1. Both forms of SL were then measured every 6 months for the next 18 months, and at the final testing session (time 4) their language proficiency was measured using a standardised test. The results showed that the reliability of the SL tasks increased across the course of the study. A series of path analyses showed that both VSL and ASL independently predicted individual differences in language proficiency at time 4. The evidence is consistent with the suggestion that, when measured reliably, an observable relationship between SL and language proficiency exists. Theoretical and methodological issues are discussed.

    Additional information

    data and code
  • Kidd, E., & Arciuli, J. (2016). Individual Differences in Statistical Learning Predict Children's Comprehension of Syntax. Child Development, 87(1), 184-193. doi:10.1111/cdev.12461.

    Abstract

    Variability in children's language acquisition is likely due to a number of cognitive and social variables. The current study investigated whether individual differences in statistical learning (SL), which has been implicated in language acquisition, independently predicted 6- to 8-year-old's comprehension of syntax. Sixty-eight (N = 68) English-speaking children completed a test of comprehension of four syntactic structures, a test of SL utilizing nonlinguistic visual stimuli, and several additional control measures. The results revealed that SL independently predicted comprehension of two syntactic structures that show considerable variability in this age range: passives and object relative clauses. These data suggest that individual differences in children's capacity for SL are associated with the acquisition of the syntax of natural languages.
  • Kidd, E., Kemp, N., Kashima, E. S., & Quinn, S. (2016). Language, culture, and group membership: An investigation into the social effects of colloquial Australian English. Journal of Cross-Cultural Psychology, 47(5), 713-733. doi:10.1177/0022022116638175.

    Abstract

    Languages are strong markers of social identity. Multiple features of language and speech, from accent to lexis to grammatical constructions, mark speakers as members of specific cultural groups. In the current article, we present two confederate-scripted studies that investigated the social effects of the Australian hypocoristic use (e.g., uggie, uni, derro)—a lexical category emblematic of Australian culture. Participants took turns with a confederate directing each other through locations on a map. In their directions, the confederate used either hypocoristic (e.g., uni) or standard forms (e.g., university). The confederate’s cultural group membership and member prototypicality were manipulated by ethnic background and accent: In a highly prototypical in-group condition, the confederate had an Anglo-Celtic background and Australian English (AusE) accent; in a low prototypical in-group condition, the confederate had an Asian background and AusE accent; and in the out-group condition, the confederate had an Asian background and non-AusE accent. Hypocoristic use resulted in significantly higher participant-rated perceived common ground with the confederate when the confederate was an in-group but not an out-group member, which in some instances was moderated by in-group identification. The results suggest that like accents, culturally significant lexical categories function as markers of in-group identity, which influence perceived social closeness during interaction.
  • Kimmel, M., Schneider, S. M., & Fisher, V. J. (2024). "Introjecting" imagery: A process model of how minds and bodies are co-enacted. Language Sciences, 102: 101602. doi:10.1016/j.langsci.2023.101602.

    Abstract

    Somatic practices frequently use imagery, typically via verbal instructions, to scaffold sensorimotor organization and experience, a phenomenon we term “introjection”. We argue that introjection is an imagery practice in which sensorimotor and conceptual aspects are co-orchestrated, suggesting the necessity of crosstalk between somatics, phenomenology, psychology, embodied-enactive cognition, and linguistic research on embodied simulation. We presently focus on the scarcely addressed details of the process necessary to enact instructions of a literal or metaphoric nature through the body. Based on vignettes from dance, Feldenkrais, and Taichi practice, we describe introjection as a complex form of processual sense-making, in which context-interpretive, mental, attentional and physical sub-processes recursively braid. Our analysis focuses on how mental and body-related processes progressively align, inform and augment each other. This dialectic requires emphasis on the active body, which implies that uni-directional models (concept ⇒ body) are inadequate and should be replaced by interactionist alternatives (concept ⇔ body). Furthermore, we emphasize that both the source image itself and the body are specifically conceptualized for the context through constructive operations, and both evolve through their interplay. At this level introjection employs representational operations that are embedded in enactive dynamics of a fully situated person.
  • Kita, S. (1997). Two-dimensional semantic analysis of Japanese mimetics. Linguistics, 35, 379-415. doi:10.1515/ling.1997.35.2.379.
  • Klein, K. M., Pendziwiat, M., Cohen, R., Appenzeller, S., De Kovel, C. G. F., Rosenow, F., Koeleman, B. P., Kuhlenbaumer, G., Sheintuch, L., Veksler, R., Friedman, A., Afawi, Z., & Helbig, I. (2016). Autosomal dominant epilepsy with auditory features: a new LGI1 family including a phenocopy with cortical dysplasia. Journal of Neurology, 263(1), 11-6. doi:10.1007/s00415-015-7921-2.
  • Klein, W., & Musan, R. (Eds.). (1999). Das deutsche Perfekt [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (113).
  • Klein, W. (1987). Das Geltende, oder: System der Überzeugungen. Zeitschrift für Literaturwissenschaft und Linguistik, (64), 10-31.
  • Klein, W., & Rieck, B.-O. (1982). Der Erwerb der Personalpronomina im ungesteuerten Spracherwerb. Zeitschrift für Literaturwissenschaft und Linguistik, 45, 35-71.
  • Klein, W. (1980). Der stand der Forschung zur deutschen Satzintonation. Linguistische Berichte, 68/80, 3-33.
  • Klein, W. (1987). Eine Verschärfung des Entscheidungsproblems. Rechtshistorisches Journal, 6, 209-210.
  • Klein, W. (1982). Einige Bemerkungen zur Frageintonation. Deutsche Sprache, 4, 289-310.

    Abstract

    In the first, critical part of this study, a small sample of simple German sentences with their empirically determined pitch contours is used to demonstrate the incorrectness of numerous currently hold views of German sentence intonation. In the second, more constructive part, several interrogative sentence types are analysed and an attempt is made to show that intonation, besides other functions, indicates the permantently changing 'thematic score' in on-going discourse as well as certain validity claims.
  • Klein, W. (1982). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 12, 7-8.
  • Klein, W. (1988). Einleitung. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 18(69), 7-8.
  • Klein, W. (Ed.). (1980). Argumentation [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (38/39).
  • Klein, W. (1980). Argumentation und Argument. Zeitschrift für Literaturwissenschaft und Linguistik, 38/39, 9-57.
  • Klein, W. (1980). Der Stand der Forschung zur deutschen Satzintonation. Linguistische Berichte, (68/80), 3-33.
  • Klein, W. (1991). Geile Binsenbüschel, sehr intime Gespielen: Ein paar Anmerkungen über Arno Schmidt als Übersetzer. Zeitschrift für Literaturwissenschaft und Linguistik, 84, 124-129.
  • Klein, W. (1997). Learner varieties are the normal case. The Clarion, 3, 4-6.
  • Klein, W. (Ed.). (1998). Kaleidoskop [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (112).
  • Klein, W. (1997). Nobels Vermächtnis, oder die Wandlungen des Idealischen. Zeitschrift für Literaturwissenschaft und Linguistik, 107, 6-18.

    Abstract

    Nobel's legacy, or the metamorphosis of what is idealistic Ever since the first Nobel prize in literature was awarded to Prudhomme in 1901, the decisions of the Swedish Academy have been subject to criticism. What is surprising in the changing decision policy as well as in its criticism is the fact that Alfred Nobel's original intentions are hardly ever taken into account: the Nobel prize is a philanthropic prize, it is not meant to select and honour the most eminent literary work but the work with maximal benefit to human beings. What is even more surprising is the fact that no one seems to care that the donator's Last Will is regularly broken.
  • Klein, W. (1982). Pronoms personnels et formes d'acquisition. Encrages, 8/9, 42-46.
  • Klein, W., & Von Stutterheim, C. (1987). Quaestio und referentielle Bewegung in Erzählungen. Linguistische Berichte, 109, 163-183.
  • Klein, W. (1991). Raumausdrücke. Linguistische Berichte, 132, 77-114.
  • Klein, W. (Ed.). (1997). Technologischer Wandel in den Philologien [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (106).
  • Klein, W., & Von Stutterheim, C. (1991). Text structure and referential movement. Arbeitsberichte des Forschungsprogramms S&P: Sprache und Pragmatik, 22.
  • Klein, W., & Perdue, C. (1997). The basic variety (or: Couldn't natural languages be much simpler?). Second Language Research, 13, 301-347. doi:10.1191/026765897666879396.

    Abstract

    In this article, we discuss the implications of the fact that adult second language learners (outside the classroom) universally develop a well-structured, efficient and simple form of language–the Basic Variety (BV). Three questions are asked as to (1) the structural properties of the BV, (2) the status of these properties and (3) why some structural properties of ‘fully fledged’ languages are more complex. First, we characterize the BV in four respects: its lexical repertoire, the principles according to which utterances are structured, and temporality and spatiality expressed. The organizational principles proposed are small in number, and interact. We analyse this interaction, describing how the BV is put to use in various complex verbal tasks, in order to establish both what its communicative potentialities are, and also those discourse contexts where the constraints come into conflict and where the variety breaks down. This latter phenomenon provides a partial answer to the third question,concerning the relative complexity of ‘fully fledged’ languages–they have devices to deal with such cases. As for the second question, it is argued firstly that the empirically established continuity of the adult acquisition process precludes any assignment of the BV to a mode of linguistic expression (e.g., ‘protolanguage’) distinct from that of ‘fully fledged’ languages and, moreover, that the organizational constraints of the BV belong to the core attributes of the human language capacity, whereas a number of complexifications not attested in the BV are less central properties of this capacity. Finally, it is shown that the notion of feature strength, as used in recent versions of Generative Grammar, allows a straightforward characterization of the BV as a special case of an I-language, in the sense of this theory. Under this perspective, the acquisition of an Ilanguage beyond the BV can essentially be described as a change in feature strength.
  • Klein, W. (1998). The contribution of second language acquisition research. Language Learning, 48, 527-550. doi:10.1111/0023-8333.00057.

    Abstract

    During the last 25 years, second language acquisition (SLA) research hasmade considerable progress, but is still far from proving a solid basis for foreign language teaching, or from a general theory of SLA. In addition, its status within the linguistic disciplines is still very low. I argue this has not much to do with low empirical or theoretical standards in the field—in this regard, SLA research is fully competitive—but with a particular perspective on the acquisition process: SLA researches learners' utterances as deviations from a certain target, instead of genuine manifestations of underlying language capacity; it analyses them in terms of what they are not rather than what they are. For some purposes such a "target deviation perspective" makes sense, but it will not help SLA researchers to substantially and independently contribute to a deeper understanding of the structure and function of the human language faculty. Therefore, these findings will remain of limited interest to other scientists until SLA researchers consider learner varieties a normal, in fact typical, manifestation of this unique human capacity.
  • Klein, W. (1980). Some remarks on Sanders' typology of elliptical coordinations. Linguistics, 18, 871-876.

    Abstract

    Starting with Ross (1970), various proposals have been made to classify elliptical coordinations and to characterize different languages according to the types of ellipses which they admit. Sanders (1977) discusses four of these proposals, shows that they are inadequate on various grounds and proposes a fifth typology whose central claim is 'evidently correct', as he states (p. 258). In the following, I shall briefly outline this typology and then show that it is inadequate, too. Since there is only one language 1 know — German — I will take all my examples from this language. Moreover, all examples will be straightforward and easy to be judged.
  • Klein, W. (Ed.). (1988). Sprache Kranker [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (69).
  • Klein, W. (1988). Sprache und Krankheit: Ein paar Anmerkungen. Zeitschrift für Literaturwissenschaft und Linguistik, 69, 9-20.
  • Klein, W. (Ed.). (1987). Sprache und Ritual [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (65).
  • Klein, W. (1980). Vorwort. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, 10, 7-8.
  • Klein, W. (1991). Was kann sich die Übersetzungswissenschaft von der Linguistik erwarten? Zeitschrift für Literaturwissenschaft und Linguistik, 84, 104-123.
  • Klein, W. (1999). Wie sich das deutsche Perfekt zusammensetzt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (113), 52-85.
  • Klein, W. (Ed.). (1982). Zweitspracherwerb [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (45).
  • Klein, W. (1998). Von der einfältigen Wißbegierde. Zeitschrift für Literaturwissenschaft und Linguistik, 112, 6-13.
  • Knol, M. J., Poot, R. A., Evans, T. E., Satizabal, C. L., Mishra, A., Sargurupremraj, M., Van der Auwera, S., Duperron, M.-G., Jian, X., Hostettler, I. C., Van Dam-Nolen, D. H. K., Lamballais, S., Pawlak, M. A., Lewis, C. E., Carrion Castillo, A., Van Erp, T. G. M., Reinbold, C. S., Shin, J., Sholz, M., Håberg, A. K. Knol, M. J., Poot, R. A., Evans, T. E., Satizabal, C. L., Mishra, A., Sargurupremraj, M., Van der Auwera, S., Duperron, M.-G., Jian, X., Hostettler, I. C., Van Dam-Nolen, D. H. K., Lamballais, S., Pawlak, M. A., Lewis, C. E., Carrion Castillo, A., Van Erp, T. G. M., Reinbold, C. S., Shin, J., Sholz, M., Håberg, A. K., Kämpe, A., Li, G. H. Y., Avinun, R., Atkins, J. R., Hsu, F.-C., Amod, A. R., Lam, M., Tsuchida, A., Teunissen, M. W. A., Aygün, N., Patel, Y., Liang, D., Beiser, A. S., Beyer, F., Bis, J. C., Bos, D., Bryan, R. N., Bülow, R., Caspers, S., Catheline, G., Cecil, C. A. M., Dalvie, S., Dartigues, J.-F., DeCarli, C., Enlund-Cerullo, M., Ford, J. M., Franke, B., Freedman, B. I., Friedrich, N., Green, M. J., Haworth, S., Helmer, C., Hoffmann, P., Homuth, G., Ikram, M. K., Jack, C. R., Jahanshad, N., Jockwitz, C., Kamatani, Y., Knodt, A. R., Li, S., Lim, K., Longstreth, W. T., Macciardi, F., The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, The Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium, Mäkitie, O., Mazoyer, B., Medland, S. E., Miyamoto, S., Moebus, S., Mosley, T. H., Muetzel, R., Mühleisen, T. W., Nagata, M., Nakahara, S., Palmer, N. D., Pausova, Z., Preda, A., Quidé, Y., Reay, W. R., Roshchupkin, G. V., Schmidt, R., Schreiner, P. J., Setoh, K., Shapland, C. Y., Sidney, S., St Pourcain, B., Stein, J. L., Tabara, Y., Teumer, A., Uhlmann, A., Van de Lught, A., Vernooij, M. W., Werring, D. J., Windham, B. G., Witte, A. V., Wittfeld, K., Yang, Q., Yoshida, K., Brunner, H. G., Le Grand, Q., Sim, K., Stein, D. J., Bowden, D. W., Cairns, M. J., Hariri, A. R., Cheung, C.-L., Andersson, S., Villringer, A., Paus, T., Chichon, S., Calhoun, V. D., Crivello, F., Launer, L. J., White, T., Koudstaal, P. J., Houlden, H., Fornage, M., Matsuda, F., Grabe, H. J., Ikram, M. A., Debette, S., Thompson, P. M., Seshadri, S., & Adams, H. H. H. (2024). Genetic variants for head size share genes and pathways with cancer. Cell Reports Medicine, 5(5): 101529. doi:10.1016/j.xcrm.2024.101529.

    Abstract

    The size of the human head is highly heritable, but genetic drivers of its variation within the general population remain unmapped. We perform a genome-wide association study on head size (N = 80,890) and identify 67 genetic loci, of which 50 are novel. Neuroimaging studies show that 17 variants affect specific brain areas, but most have widespread effects. Gene set enrichment is observed for various cancers and the p53, Wnt, and ErbB signaling pathways. Genes harboring lead variants are enriched for macrocephaly syndrome genes (37-fold) and high-fidelity cancer genes (9-fold), which is not seen for human height variants. Head size variants are also near genes preferentially expressed in intermediate progenitor cells, neural cells linked to evolutionary brain expansion. Our results indicate that genes regulating early brain and cranial growth incline to neoplasia later in life, irrespective of height. This warrants investigation of clinical implications of the link between head size and cancer.

    Additional information

    link to supplemental information

Share this page