Publications

Abstract

Moving in synchrony to the beat is a fundamental component of musicality. Here we conducted a genome-wide association study to identify common genetic variants associated with beat synchronization in 606,825 individuals. Beat synchronization exhibited a highly polygenic architecture, with 69 loci reaching genome-wide significance (P < 5 × 10−8) and single-nucleotide-polymorphism-based heritability (on the liability scale) of 13%–16%. Heritability was enriched for genes expressed in brain tissues and for fetal and adult brain-specific gene regulatory elements, underscoring the role of central-nervous-system-expressed genes linked to the genetic basis of the trait. We performed validations of the self-report phenotype (through separate experiments) and of the genome-wide association study (polygenic scores for beat synchronization were associated with patients algorithmically classified as musicians in medical records of a separate biobank). Genetic correlations with breathing function, motor function, processing speed and chronotype suggest shared genetic architecture with beat synchronization and provide avenues for new phenotypic and genetic explorations.

Abstract

This study compares the role of exemplars in native and non-native listening. Two English identity priming experiments were conducted with native English, Dutch non-native, and Spanish non-native listeners. In Experiment 1, primes and targets were spoken in the same or a different voice. Only the native listeners showed exemplar effects. In Experiment 2, primes and targets had the same or a different degree of vowel reduction. The Dutch, but not the Spanish, listeners were familiar with this reduction pattern from their L1 phonology. In this experiment, exemplar effects only arose for the Spanish listeners. We propose that in these lexical decision experiments the use of exemplars is co-determined by listeners’ available processing resources, which is modulated by the familiarity with the variation type from their L1 phonology. The use of exemplars differs between native and non-native listening, suggesting qualitative differences between native and non-native speech comprehension processes.

Abstract

Research using the intermodal preferential looking paradigm (IPLP) has consistently shown that English-learning children aged 2 can associate transitive argument structure with causal events. However, studies using the same methodology investigating 2-year-old children’s knowledge of the conjoined agent intransitive and semantic role assignment have reported inconsistent findings. The aim of the present study was to establish at what age English-learning children have verb-general knowledge of both transitive and intransitive argument structure using a new method: the forced-choice pointing paradigm. The results suggest that young 2-year-olds can associate transitive structures with causal (or externally caused) events and can use transitive structure to assign agent and patient roles correctly. However, the children were unable to associate the conjoined agent intransitive with noncausal events until aged 3;4. The results confirm the pattern from previous IPLP studies and indicate that children may develop the ability to comprehend different aspects of argument structure at different ages. The implications for theories of language acquisition and the nature of the language acquisition mechanism are discussed.

Abstract

Psycholinguistic theories are based on a very small set of unrepresentative languages, so it is as yet unclear how typological variation shapes mechanisms supporting language use. In this article we report the first on-line experimental study of sentence production in an Australian free word order language: Murrinhpatha. Forty-six adult native speakers of Murrinhpatha described a series of unrelated transitive scenes that were manipulated for humanness (±human) in the agent and patient roles while their eye movements were recorded. Speakers produced a large range of word orders, consistent with the language having flexible word order, with variation significantly influenced by agent and patient humanness. An analysis of eye movements showed that Murrinhpatha speakers' first fixation on an event character did not alone determine word order; rather, early in speech planning participants rapidly encoded both event characters and their relationship to each other. That is, they engaged in relational encoding, laying down a very early conceptual foundation for the word order they eventually produced. These results support a weakly hierarchical account of sentence production and show that speakers of a free word order language encode the relationships between event participants during earlier stages of sentence planning than is typically observed for languages with fixed word orders.

Abstract

Background: Perioperative assessment of language function in brain tumor patients commonly relies on administration of object naming during stimulation mapping. Ample research, however, points to the benefit of adding verb tasks to the testing paradigm in order to delineate and preserve postoperative language function more comprehensively. This research uses a case series approach to explore the feasibility and added value of a dual-task protocol that includes both a noun task (object naming) and a verb task (action naming) in perioperative delineation of language functions.

Materials and Methods: Seven neurosurgical cases underwent perioperative language assessment with both object and action naming. This entailed preoperative baseline testing, preoperative stimulation mapping with navigated Transcranial Magnetic Stimulation (nTMS) with subsequent white matter visualization, intraoperative mapping with Direct Electrical Stimulation (DES) in 4 cases, and postoperative imaging and examination of language change.

Results: We observed a divergent pattern of language organization and decline between cases who showed lesions close to the delineated language network and hence underwent DES mapping, and those that did not. The latter displayed no new impairment postoperatively consistent with an unharmed network for the neural circuits of both object and action naming. For the cases who underwent DES, on the other hand, a higher sensitivity was found for action naming over object naming. Firstly, action naming preferentially predicted the overall language state compared to aphasia batteries. Secondly, it more accurately predicted intraoperative positive language areas as revealed by DES. Thirdly, double dissociations between postoperatively unimpaired object naming and impaired action naming and vice versa indicate segregated skills and neural representation for noun versus verb processing, especially in the ventral stream. Overlaying postoperative imaging with object and action naming networks revealed that dual-task nTMS mapping can explain the drop in performance in those cases where the network appeared in proximity to the resection cavity.

Conclusion: Using a dual-task protocol for visualization of cortical and subcortical language areas through nTMS mapping proved to be able to capture network-to-deficit relations in our case series. Ultimately, adding action naming to clinical nTMS and DES mapping may help prevent postoperative deficits of this seemingly segregated skill.

Abstract

We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half the PGI’s magnitude of association with EA and other phenotypes. The correlation between mate-pair PGIs is far too large to be consistent with phenotypic assortment alone, implying additional assortment on PGI-associated factors. In an additional GWAS of dominance deviations from the additive model, we identify no genome-wide-significant SNPs, and a separate X-chromosome additive GWAS identifies 57.

Abstract

Despite growing clinical and neurobiological interest in the brain mechanisms that process emotion in music, these mechanisms remain incompletely understood. Patients with frontotemporal lobar degeneration (FTLD) frequently exhibit clinical syndromes that illustrate the effects of breakdown in emotional and social functioning. Here we investigated the neuroanatomical substrate for recognition of musical emotion in a cohort of 26 patients with FTLD (16 with behavioural variant frontotemporal dementia, bvFTD, 10 with semantic dementia, SemD) using voxel-based morphometry. On neuropsychological evaluation, patients with FTLD showed deficient recognition of canonical emotions (happiness, sadness, anger and fear) from music as well as faces and voices compared with healthy control subjects. Impaired recognition of emotions from music was specifically associated with grey matter loss in a distributed cerebral network including insula, orbitofrontal cortex, anterior cingulate and medial prefrontal cortex, anterior temporal and more posterior temporal and parietal cortices, amygdala and the subcortical mesolimbic system. This network constitutes an essential brain substrate for recognition of musical emotion that overlaps with brain regions previously implicated in coding emotional value, behavioural context, conceptual knowledge and theory of mind. Musical emotion recognition may probe the interface of these processes, delineating a profile of brain damage that is essential for the abstraction of complex social emotions.

Abstract

The centrosome provides an intracellular anchor for the cytoskeleton, regulating cell division, cell migration, and cilia formation. We used spatial proteomics to elucidate protein interaction networks at the centrosome of human induced pluripotent stem cell–derived neural stem cells (NSCs) and neurons. Centrosome-associated proteins were largely cell type–specific, with protein hubs involved in RNA dynamics. Analysis of neurodevelopmental disease cohorts identified a significant overrepresentation of NSC centrosome proteins with variants in patients with periventricular heterotopia (PH). Expressing the PH-associated mutant pre-mRNA-processing factor 6 (PRPF6) reproduced the periventricular misplacement in the developing mouse brain, highlighting missplicing of transcripts of a microtubule-associated kinase with centrosomal location as essential for the phenotype. Collectively, cell type–specific centrosome interactomes explain how genetic variants in ubiquitous proteins may convey brain-specific phenotypes.

Abstract

Prediction is one characteristic of the human mind. But what does it mean to say the mind is a ’prediction machine’ and inherently forward looking as is frequently claimed? In natural languages, many contexts are not easily predictable in a forward fashion. In English for example many frequent verbs do not carry unique meaning on their own, but instead rely on another word or words that follow them to become meaningful. Upon reading take a the processor often cannot easily predict walk as the next word. But the system can ‘look back’ and integrate walk more easily when it follows take a (e.g., as opposed to make|get|have a walk). In the present paper we provide further evidence for the importance of both forward and backward looking in language processing. In two self-paced reading tasks and an eye-tracking reading task, we found evidence that adult English native speakers’ sensitivity to word forward and backward conditional probability significantly explained variance in reading times over and above psycholinguistic predictors of reading latencies. We conclude that both forward and backward-looking (prediction and integration) appear to be important characteristics of language processing. Our results thus suggest that it makes just as much sense to call the mind an ’integration machine’ which is inherently backward looking.

Abstract

This paper describes FieldTrip, an open source software package that we developed for the analysis of MEG, EEG, and other electrophysiological data. The software is implemented as a MATLAB toolbox and includes a complete set of consistent and user-friendly high-level functions that allow experimental neuroscientists to analyze experimental data. It includes algorithms for simple and advanced analysis, such as time-frequency analysis using multitapers, source reconstruction using dipoles, distributed sources and beamformers, connectivity analysis, and nonparametric statistical permutation tests at the channel and source level. The implementation as toolbox allows the user to perform elaborate and structured analyses of large data sets using the MATLAB command line and batch scripting. Furthermore, users and developers can easily extend the functionality and implement new algorithms. The modular design facilitates the reuse in other software packages.

Abstract

Evidence for the etiology of autism spectrum disorders (ASDs) has consistently pointed to a strong genetic component complicated by substantial locus heterogeneity1, 2. We sequenced the exomes of 20 individuals with sporadic ASD (cases) and their parents, reasoning that these families would be enriched for de novo mutations of major effect. We identified 21 de novo mutations, 11 of which were protein altering. Protein-altering mutations were significantly enriched for changes at highly conserved residues. We identified potentially causative de novo events in 4 out of 20 probands, particularly among more severely affected individuals, in FOXP1, GRIN2B, SCN1A and LAMC3. In the FOXP1 mutation carrier, we also observed a rare inherited CNTNAP2 missense variant, and we provide functional support for a multi-hit model for disease risk3. Our results show that trio-based exome sequencing is a powerful approach for identifying new candidate genes for ASDs and suggest that de novo mutations may contribute substantially to the genetic etiology of ASDs.

Abstract

The field of bioacoustics is rapidly developing and characterized by diverse methodologies, approaches and aims. For instance, bioacoustics encompasses studies on the perception of pure tones in meticulously controlled laboratory settings, documentation of species’ presence and activities using recordings from the field, and analyses of circadian calling patterns in animal choruses. Newcomers to the field are confronted with a vast and fragmented literature, and a lack of accessible reference papers or textbooks. In this paper we contribute towards filling this gap. Instead of a classical list of “dos” and “don’ts”, we review some key papers which, we believe, embody best practices in several bioacoustic subfields. In the first three case studies, we discuss how bioacoustics can help identify the ‘who’, ‘where’ and ‘how many’ of animals within a given ecosystem. Specifically, we review cases in which bioacoustic methods have been applied with success to draw inferences regarding species identification, population structure, and biodiversity. In fourth and fifth case studies, we highlight how structural properties in signal evolution can emerge via ecological constraints or cultural transmission. Finally, in a sixth example, we discuss acoustic methods that have been used to infer predator–prey dynamics in cases where direct observation was not feasible. Across all these examples, we emphasize the importance of appropriate recording parameters and experimental design. We conclude by highlighting common best practices across studies as well as caveats about our own overview. We hope our efforts spur a more general effort in standardizing best practices across the subareas we’ve highlighted in order to increase compatibility among bioacoustic studies and inspire cross-pollination across the discipline.

Abstract

The archaeological site of Sagalassos is located in Southwest Turkey, in the western part of the Taurus mountain range. Human occupation of its territory is attested from the late 12th millennium BP up to the 13th century AD. By analysing the mtDNA variation in 85 skeletons from Sagalassos dated to the 11th–13th century AD, this study attempts to reconstruct the genetic signature potentially left in this region of Anatolia by the many civilizations, which succeeded one another over the centuries until the mid-Byzantine period (13th century BC). Authentic ancient DNA data were determined from the control region and some SNPs in the coding region of the mtDNA in 53 individuals. Comparative analyses with up to 157 modern populations allowed us to reconstruct the origin of the mid-Byzantine people still dwelling in dispersed hamlets in Sagalassos, and to detect the maternal contribution of their potential ancestors. By integrating the genetic data with historical and archaeological information, we were able to attest in Sagalassos a significant maternal genetic signature of Balkan/Greek populations, as well as ancient Persians and populations from the Italian peninsula. Some contribution from the Levant has been also detected, whereas no contribution from Central Asian population could be ascertained.

Abstract

In this increasingly data-rich world, visual recordings of human behavior are often unable to be shared due to concerns about privacy. Consequently, data sharing in fields such as behavioral science, multimodal communication, and human movement research is often limited. In addition, in legal and other non-scientific contexts, privacy-related concerns may preclude the sharing of video recordings and thus remove the rich multimodal context that humans recruit to communicate. Minimizing the risk of identity exposure while preserving critical behavioral information would maximize utility of public resources (e.g., research grants) and time invested in audio–visual​ research. Here we present an open-source computer vision tool that masks the identities of humans while maintaining rich information about communicative body movements. Furthermore, this masking tool can be easily applied to many videos, leveraging computational tools to augment the reproducibility and accessibility of behavioral research. The tool is designed for researchers and practitioners engaged in kinematic and affective research. Application areas include teaching/education, communication and human movement research, CCTV, and legal contexts.

Abstract

Hearing one’s own voice is critical for fluent speech production as it allows for the detection and correction of vocalization errors in real time. This behavior known as the auditory feedback control of speech is impaired in various neurological disorders ranging from stuttering to aphasia; however, the underlying neural mechanisms are still poorly understood. Computational models of speech motor control suggest that, during speech production, the brain uses an efference copy of the motor command to generate an internal estimate of the speech output. When actual feedback differs from this internal estimate, an error signal is generated to correct the internal estimate and update necessary motor commands to produce intended speech. We were able to localize the auditory error signal using electrocorticographic recordings from neurosurgical participants during a delayed auditory feedback (DAF) paradigm. In this task, participants hear their voice with a time delay as they produced words and sentences (similar to an echo on a conference call), which is well known to disrupt fluency by causing slow and stutter-like speech in humans. We observed a significant response enhancement in auditory cortex that scaled with the duration of feedback delay, indicating an auditory speech error signal. Immediately following auditory cortex, dorsal precentral gyrus (dPreCG), a region that has not been implicated in auditory feedback processing before, exhibited a markedly similar response enhancement, suggesting a tight coupling between the 2 regions. Critically, response enhancement in dPreCG occurred only during articulation of long utterances due to a continuous mismatch between produced speech and reafferent feedback. These results suggest that dPreCG plays an essential role in processing auditory error signals during speech production to maintain fluency.

Abstract

Temporal lobe epilepsy (TLE), a common drug-resistant epilepsy in adults, is primarily a limbic network disorder associated with predominant unilateral hippocampal pathology. Structural MRI has provided an in vivo window into whole-brain grey matter structural alterations in TLE relative to controls, by either mapping (i) atypical inter-hemispheric asymmetry or (ii) regional atrophy. However, similarities and differences of both atypical asymmetry and regional atrophy measures have not been systematically investigated.

Here, we addressed this gap using the multi-site ENIGMA-Epilepsy dataset comprising MRI brain morphological measures in 732 TLE patients and 1,418 healthy controls. We compared spatial distributions of grey matter asymmetry and atrophy in TLE, contextualized their topographies relative to spatial gradients in cortical microstructure and functional connectivity calculated using 207 healthy controls obtained from Human Connectome Project and an independent dataset containing 23 TLE patients and 53 healthy controls, and examined clinical associations using machine learning.

We identified a marked divergence in the spatial distribution of atypical inter-hemispheric asymmetry and regional atrophy mapping. The former revealed a temporo-limbic disease signature while the latter showed diffuse and bilateral patterns. Our findings were robust across individual sites and patients. Cortical atrophy was significantly correlated with disease duration and age at seizure onset, while degrees of asymmetry did not show a significant relationship to these clinical variables.

Our findings highlight that the mapping of atypical inter-hemispheric asymmetry and regional atrophy tap into two complementary aspects of TLE-related pathology, with the former revealing primary substrates in ipsilateral limbic circuits and the latter capturing bilateral disease effects. These findings refine our notion of the neuropathology of TLE and may inform future discovery and validation of complementary MRI biomarkers in TLE.

Abstract

Background Thirty-two common variants associated with body mass index (BMI) have been identified in genome-wide association studies, explaining ∼1.45% of BMI variation in general population cohorts. We performed a genome-wide association study in a sample of young adults enriched for extremely overweight individuals. We aimed to identify new loci associated with BMI and to ascertain whether using an extreme sampling design would identify the variants known to be associated with BMI in general populations. Methodology/Principal Findings From two large Danish cohorts we selected all extremely overweight young men and women (n = 2,633), and equal numbers of population-based controls (n = 2,740, drawn randomly from the same populations as the extremes, representing ∼212,000 individuals). We followed up novel (at the time of the study) association signals (p<}0.001) from the discovery cohort in a genome-wide study of 5,846 Europeans, before attempting to replicate the most strongly associated 28 SNPs in an independent sample of Danish individuals (n = 20,917) and a population-based cohort of 15-year-old British adolescents (n = 2,418). Our discovery analysis identified SNPs at three loci known to be associated with BMI with genome-wide confidence (P{<}5×10−8; FTO, MC4R and FAIM2). We also found strong evidence of association at the known TMEM18, GNPDA2, SEC16B, TFAP2B, SH2B1 and KCTD15 loci (p{<}0.001), and nominal association (p{<0.05) at a further 8 loci known to be associated with BMI. However, meta-analyses of our discovery and replication cohorts identified no novel associations. Significance Our results indicate that the detectable genetic variation associated with extreme overweight is very similar to that previously found for general BMI. This suggests that population-based study designs with enriched sampling of individuals with the extreme phenotype may be an efficient method for identifying common variants that influence quantitative traits and a valid alternative to genotyping all individuals in large population-based studies, which may require tens of thousands of subjects to achieve similar power.

Abstract

In many musical styles, vocalists manually gesture while they sing. Coupling between gesture kinematics and vocalization has been examined in speech contexts, but it is an open question how these couple in music making. We examine this in a corpus of South Indian, Karnatak vocal music that includes motion-capture data. Through peak magnitude analysis (linear mixed regression) and continuous time-series analyses (generalized additive modeling), we assessed whether vocal trajectories around peaks in vertical velocity, speed, or acceleration were coupling with changes in vocal acoustics (namely, F0 and amplitude). Kinematic coupling was stronger for F0 change versus amplitude, pointing to F0's musical significance. Acceleration was the most predictive for F0 change and had the most reliable magnitude coupling, showing a one-third power relation. That acceleration, rather than other kinematics, is maximally predictive for vocalization is interesting because acceleration entails force transfers onto the body. As a theoretical contribution, we argue that gesturing in musical contexts should be understood in relation to the physical connections between gesturing and vocal production that are brought into harmony with the vocalists’ (enculturated) performance goals. Gesture–vocal coupling should, therefore, be viewed as a neuro–bodily distributed aesthetic entanglement.

Abstract

Models on L3/Ln acquisition differ with respect to how they envisage degree (holistic
vs. selective transfer of the L1, L2 or both) and/or timing (initial stages vs. development) of how
the influence of source languages unfolds. This study uses EEG/ERPs to examine these models,
bringing together two types of bilinguals: heritage speakers (HSs) (Italian-German, n = 15) compared
to adult L2 learners (L1 German, L2 English, n = 28) learning L3/Ln Latin. Participants were trained
on a selected Latin lexicon over two sessions and, afterward, on two grammatical properties: case
(similar between German and Latin) and adjective–noun order (similar between Italian and Latin).
Neurophysiological findings show an N200/N400 deflection for the HSs in case morphology and a
P600 effect for the German L2 group in adjectival position. None of the current L3/Ln models predict
the observed results, which questions the appropriateness of this methodology. Nevertheless, the
results are illustrative of differences in how HSs and L2 learners approach the very initial stages of
additional language learning, the implications of which are discussed

Abstract

The present study uses EEG time-frequency representations (TFRs) with a Flanker task to investigate if and how individual differences in bilingual language experience modulate neurocognitive outcomes (oscillatory dynamics) in two bilingual group types: late bilinguals (L2 learners) and early bilinguals (heritage speakers—HSs). TFRs were computed for both incongruent and congruent trials. The difference between the two (Flanker effect vis-à-vis cognitive interference) was then (1) compared between the HSs and the L2 learners, (2) modeled as a function of individual differences with bilingual experience within each group separately and (3) probed for its potential (a)symmetry between brain and behavioral data. We found no differences at the behavioral and neural levels for the between-groups comparisons. However, oscillatory dynamics (mainly theta increase and alpha suppression) of inhibition and cognitive control were found to be modulated by individual differences in bilingual language experience, albeit distinctly within each bilingual group. While the results indicate adaptations toward differential brain recruitment in line with bilingual language experience variation overall, this does not manifest uniformly. Rather, earlier versus later onset to bilingualism—the bilingual type—seems to constitute an independent qualifier to how individual differences play out.

Abstract

Humans have the ability to learn surprisingly complicated statistical information in a variety of modalities and situations, often based on relatively little input. These statistical learning (SL) skills appear to underlie many kinds of learning, but despite their ubiquity, we still do not fully understand precisely what SL is and what individual differences on SL tasks reflect. Here, we present experimental work suggesting that at least some individual differences arise from stimulus-specific variation in perceptual fluency: the ability to rapidly or efficiently code and remember the stimuli that SL occurs over. Experiment 1 demonstrates that participants show improved SL when the stimuli are simple and familiar; Experiment 2 shows that this improvement is not evident for simple but unfamiliar stimuli; and Experiment 3 shows that for the same stimuli (Chinese characters), SL is higher for people who are familiar with them (Chinese speakers) than those who are not (English speakers matched on age and education level). Overall, our findings indicate that performance on a standard SL task varies substantially within the same (visual) modality as a function of whether the stimuli involved are familiar or not, independent of stimulus complexity. Moreover, test–retest correlations of performance in an SL task using stimuli of the same level of familiarity (but distinct items) are stronger than correlations across the same task with stimuli of different levels of familiarity. Finally, we demonstrate that SL performance is predicted by an independent measure of stimulus-specific perceptual fluency that contains no SL component at all. Our results suggest that a key component of SL performance may be related to stimulus-specific processing and familiarity.

Abstract

Background

Noncoding RNA (ncRNA) has been recognized as an important regulator of gene expression networks in Bacteria and Eucaryota. Little is known about ncRNA in thermococcal archaea except for the eukaryotic-like C/D and H/ACA modification guide RNAs.
Results

Using a combination of in silico and experimental approaches, we identified and characterized novel P. abyssi ncRNAs transcribed from 12 intergenic regions, ten of which are conserved throughout the Thermococcales. Several of them accumulate in the late-exponential phase of growth. Analysis of the genomic context and sequence conservation amongst related thermococcal species revealed two novel P. abyssi ncRNA families. The CRISPR family is comprised of crRNAs expressed from two of the four P. abyssi CRISPR cassettes. The 5'UTR derived family includes four conserved ncRNAs, two of which have features similar to known bacterial riboswitches. Several of the novel ncRNAs have sequence similarities to orphan OrfB transposase elements. Based on RNA secondary structure predictions and experimental results, we show that three of the twelve ncRNAs include Kink-turn RNA motifs, arguing for a biological role of these ncRNAs in the cell. Furthermore, our results show that several of the ncRNAs are subjected to processing events by enzymes that remain to be identified and characterized.
Conclusions

This work proposes a revised annotation of CRISPR loci in P. abyssi and expands our knowledge of ncRNAs in the Thermococcales, thus providing a starting point for studies needed to elucidate their biological function.

Abstract

Disagreement exists about whether lexical selection in word production is a competitive process. Competition predicts semanticinterference from distractor words in immediate but not in delayed picture naming. In contrast, Janssen, Schirm, Mahon, and Caramazza (2008) obtained semanticinterference in delayed picture naming when participants had to decide between picture naming and oral reading depending on the distractor word’s colour. We report three experiments that examined the role of such taskdecisions. In a single-task situation requiring picture naming only (Experiment 1), we obtained semanticinterference in immediate but not in delayednaming. In a task-decision situation (Experiments 2 and 3), no semantic effects were obtained in immediate and delayed picture naming and word reading using either the materials of Experiment 1 or the materials of Janssen et al. (2008). We present an attentional account in which taskdecisions may hide or reveal semanticinterference from lexical competition depending on the amount of parallelism between task-decision and picture–word processing.

Abstract

Defeasible inferences are inferences that can be revised in the light of new information. Although defeasible inferences are pervasive in everyday communication, little is known about how and when they are processed by the brain. This study examined the electrophysiological signature of defeasible reasoning using a modified version of the suppression task. Participants were presented with conditional inferences (of the type “if p, then q; p, therefore q”) that were preceded by a congruent or a disabling context. The disabling context contained a possible exception or precondition that prevented people from drawing the conclusion. Acceptability of the conclusion was indeed lower in the disabling condition compared to the congruent condition. Further, we found a large sustained negativity at the conclusion of the disabling condition relative to the congruent condition, which started around 250 msec and was persistent throughout the entire epoch. Possible accounts for the observed effect are discussed.

Abstract

Many word forms exist in multiple languages, and can have either the same meaning (cognates) or a different meaning (interlingual homographs). Previous experiments have shown that processing of interlingual homographs in a bilingual’s second language is slowed down by recent experience with these words in the bilingual’s native language, while processing of cognates can be speeded up (Poort et al., 2016; Poort & Rodd, 2019a). The current experiment replicated Poort and Rodd’s (2019a) Experiment 2 but switched the direction of priming: Dutch–English bilinguals (n = 106) made Dutch semantic relatedness judgements to probes related to cognates (n = 50), interlingual homographs (n = 50) and translation equivalents (n = 50) they had seen 15 minutes previously embedded in English sentences. The current experiment is the first to show that a single encounter with an interlingual homograph in one’s second language can also affect subsequent processing in one’s native language. Cross-lingual priming did not affect the cognates. The experiment also extended Poort and Rodd (2019a)’s finding of a large interlingual homograph inhibition effect in a semantic relatedness task in the participants’ L2 to their L1, but again found no evidence for a cognate facilitation effect in a semantic relatedness task. These findings extend the growing literature that emphasises the high level of interaction in a bilingual’s mental lexicon, by demonstrating the influence of L2 experience on the processing of L1 words. Data, scripts, materials and pre-registration available via https://osf.io/2swyg/?view_only=b2ba2e627f6f4eaeac87edab2b59b236.

Abstract

Combining academics and athletics is challenging but important for the psychological and psychosocial development of those involved. However, little is known about how experiences in academics spill over and relate to athletics. Drawing on the enrichment mechanisms proposed by the Work-Home Resources model, we posit that study crafting behaviours are positively related to volatile personal resources, which, in turn, are related to higher athletic achievement. Via structural equation modelling, we examine a path model among 243 student-athletes, incorporating study crafting behaviours and personal resources (i.e., positive affect and study engagement), and self- and coach-rated athletic achievement measured two weeks later. Results show that optimising the academic environment by crafting challenging study demands relates positively to positive affect and study engagement. In turn, positive affect related positively to self-rated athletic achievement, whereas – unexpectedly – study engagement related negatively to coach-rated athletic achievement. Optimising the academic environment through cognitive crafting and crafting social study resources did not relate to athletic outcomes. We discuss how these findings offer new insights into the interplay between academics and athletics.

Abstract

Prediction-based theories of language comprehension assume that listeners predict both the meaning and phonological form of likely upcoming words. In alleged event-related potential (ERP) demonstrations of phonological prediction, prediction-mismatching words elicit a phonological mismatch negativity (PMN), a frontocentral negativity that precedes the centroparietal N400 component. However, classification and replicability of the PMN has proven controversial, with ongoing debate on whether the PMN is a distinct component or merely an early part of the N400. In this electroencephalography (EEG) study, we therefore attempted to replicate the PMN effect and its separability from the N400, using a participant sample size (N = 48) that was more than double that of previous studies. Participants listened to sentences containing either a predictable word or an unpredictable word with/without phonological overlap with the predictable word. Preregistered analyses revealed a widely distributed negative-going ERP in response to unpredictable words in both the early (150–250 ms) and the N400 (300–500 ms) time windows. Bayes factor analysis yielded moderate evidence against a different scalp distribution of the effects in the two time windows. Although our findings do not speak against phonological prediction during sentence comprehension, they do speak against the PMN effect specifically as a marker of phonological prediction mismatch. Instead of an PMN effect, our results demonstrate the early onset of the auditory N400 effect associated with unpredictable words. Our failure to replicate further highlights the risk associated with commonly employed data-contingent analyses (e.g., analyses involving time windows or electrodes that were selected based on visual inspection) and small sample sizes in the cognitive neuroscience of language.

Abstract

OBJECTIVE: There is overlap between an autistic and hyperactive-inattentive symptomatology when studied cross-sectionally. This study is the first to examine the longitudinal pattern of association between social-communication deficits and hyperactive-inattentive symptoms in the general population, from childhood through adolescence. We explored the interrelationship between trajectories of co-occurring symptoms, and sought evidence for shared prenatal/perinatal risk factors. METHOD: Study participants were 5,383 singletons of white ethnicity from the Avon Longitudinal Study of Parents and Children (ALSPAC). Multiple measurements of hyperactive-inattentive traits (Strengths and Difficulties Questionnaire) and autistic social-communication impairment (Social Communication Disorder Checklist) were obtained between 4 and 17 years. Both traits and their trajectories were modeled in parallel using latent class growth analysis (LCGA). Trajectory membership was subsequently investigated with respect to prenatal/perinatal risk factors. RESULTS: LCGA analysis revealed two distinct social-communication trajectories (persistently impaired versus low-risk) and four hyperactive-inattentive trait trajectories (persistently impaired, intermediate, childhood-limited and low-risk). Autistic symptoms were more stable than those of attention-deficit/hyperactivity disorder (ADHD) behaviors, which showed greater variability. Trajectories for both traits were strongly but not reciprocally interlinked, such that the majority of children with a persistent hyperactive-inattentive symptomatology also showed persistent social-communication deficits but not vice versa. Shared predictors, especially for trajectories of persistent impairment, were maternal smoking during the first trimester, which included familial effects, and a teenage pregnancy. CONCLUSIONS: Our longitudinal study reveals that a complex relationship exists between social-communication and hyperactive-inattentive traits. Patterns of association change over time, with corresponding implications for removing exclusivity criteria for ASD and ADHD, as proposed for DSM-5.

Abstract

Conversational turn taking in humans involves incredibly rapid responding. The timing mechanisms underpinning such responses have been heavily debated, including questions such as who is doing the timing. Similar to findings on rhythmic tapping to a metronome, we show that floor transfer offsets (FTOs) in telephone conversations are serially dependent, such that FTOs are lag-1 negatively autocorrelated. Finding this serial dependence on a turn-by-turn basis (lag-1) rather than on the basis of two or more turns, suggests a counter-adjustment mechanism operating at the level of the dyad in FTOs during telephone conversations, rather than a more individualistic self-adjustment within speakers. This finding, if replicated, has major implications for models describing turn taking, and confirms the joint, dyadic nature of human conversational dynamics. Future research is needed to see how pervasive serial dependencies in FTOs are, such as for example in richer communicative face-to-face contexts where visual signals affect conversational timing.

Abstract

Do communicative actions such as gestures fundamentally differ in their control mechanisms from other actions? Evidence for such fundamental differences comes from a classic gesture-speech coordination experiment performed with a person (IW) with deafferentation (McNeill, 2005). Although IW has lost both his primary source of information about body position (i.e., proprioception) and discriminative touch from the neck down, his gesture-speech coordination has been reported to be largely unaffected, even if his vision is blocked. This is surprising because, without vision, his object-directed actions almost completely break down. We examine the hypothesis that IW’s gesture-speech coordination is supported by the biomechanical effects of gesturing on head posture and speech. We find that when vision is blocked, there are micro-scale increases in gesture-speech timing variability, consistent with IW’s reported experience that gesturing is difficult without vision. Supporting the hypothesis that IW exploits biomechanical consequences of the act of gesturing, we find that: (1) gestures with larger physical impulses co-occur with greater head movement, (2) gesture-speech synchrony relates to larger gesture-concurrent head movements (i.e. for bimanual gestures), (3) when vision is blocked, gestures generate more physical impulse, and (4) moments of acoustic prominence couple more with peaks of physical impulse when vision is blocked. It can be concluded that IW’s gesturing ability is not based on a specialized language-based feedforward control as originally concluded from previous research, but is still dependent on a varied means of recurrent feedback from the body.

Abstract

Gestures during speaking are typically understood in a representational framework: they represent absent or distal states of affairs by means of pointing, resemblance, or symbolic replacement. However, humans also gesture along with the rhythm of speaking, which is amenable to a non-representational perspective. Such a perspective centers on the phenomenon of vocal-entangled gestures and builds on evidence showing that when an upper limb with a certain mass decelerates/accelerates sufficiently, it yields impulses on the body that cascade in various ways into the respiratory–vocal system. It entails a physical entanglement between body motions, respiration, and vocal activities. It is shown that vocal-entangled gestures are realized in infant vocal–motor babbling before any representational use of gesture develops. Similarly, an overview is given of vocal-entangled processes in non-human animals. They can frequently be found in rats, bats, birds, and a range of other species that developed even earlier in the phylogenetic tree. Thus, the origins of human gesture lie in biomechanics, emerging early in ontogeny and running deep in phylogeny.

Abstract

Objective—The vascular competence of human-derived hematopoietic progenitors for postnatal vascularization is still poorly characterized. It is unclear whether, in the absence of ischemia, hematopoietic progenitors participate in neovascularization and whether they play a role in new blood vessel formation by incorporating into developing vessels or by a paracrine action. Methods and Results—In the present study, human cord blood–derived CD34+ (hCD34+) cells were transplanted into pre- and postgastrulation zebrafish embryos and in an adult vascular regeneration model induced by caudal fin amputation. When injected before gastrulation, hCD34+ cells cosegregated with the presumptive zebrafish hemangioblasts, characterized by Scl and Gata2 expression, in the anterior and posterior lateral mesoderm and were involved in early development of the embryonic vasculature. These morphogenetic events occurred without apparent lineage reprogramming, as shown by CD45 expression. When transplanted postgastrulation, hCD34+ cells were recruited into developing vessels, where they exhibited a potent paracrine proangiogenic action. Finally, hCD34+ cells rescued vascular defects induced by Vegf-c in vivo targeting and enhanced vascular repair in the zebrafish fin amputation model. Conclusion—These results indicate an unexpected developmental ability of human-derived hematopoietic progenitors and support the hypothesis of an evolutionary conservation of molecular pathways involved in endothelial progenitor differentiation in vivo.

Abstract

There is considerable individual variability in the reported effectiveness of non-invasive brain stimulation. This variability has often been ascribed to differences in the neuroanatomy and resulting differences in the induced electric field inside the brain. In this study, we addressed the question whether individual differences in the induced electric field can predict the neurophysiological and behavioral consequences of gamma band tACS. In a within-subject experiment, bi-hemispheric gamma band tACS and sham stimulation was applied in alternating blocks to the participants’ superior temporal lobe, while task-evoked auditory brain activity was measured with concurrent functional magnetic resonance imaging (fMRI) and a dichotic listening task. Gamma tACS was applied with different interhemispheric phase lags. In a recent study, we could show that anti-phase tACS (180° interhemispheric phase lag), but not in-phase tACS (0° interhemispheric phase lag), selectively modulates interhemispheric brain connectivity. Using a T1 structural image of each participant’s brain, an individual simulation of the induced electric field was computed. From these simulations, we derived two predictor variables: maximal strength (average of the 10,000 voxels with largest electric field values) and precision of the electric field (spatial correlation between the electric field and the task evoked brain activity during sham stimulation). We found considerable variability in the individual strength and precision of the electric fields. Importantly, the strength of the electric field over the right hemisphere predicted individual differences of tACS induced brain connectivity changes. Moreover, we found in both hemispheres a statistical trend for the effect of electric field strength on tACS induced BOLD signal changes. In contrast, the precision of the electric field did not predict any neurophysiological measure. Further, neither strength, nor precision predicted interhemispheric integration. In conclusion, we found evidence for the dose-response relationship between individual differences in electric fields and tACS induced activity and connectivity changes in concurrent fMRI. However, the fact that this relationship was stronger in the right hemisphere suggests that the relationship between the electric field parameters, neurophysiology, and behavior may be more complex for bi-hemispheric tACS.

Abstract

Which processes in the human brain lead to the categorical perception of speech sounds? Investigation of this question is hampered by the fact that categorical speech perception is normally confounded by acoustic differences in the stimulus. By using ambiguous sounds, however, it is possible to dissociate acoustic from perceptual stimulus representations. Twenty-seven normally hearing individuals took part in an fMRI study in which they were presented with an ambiguous syllable (intermediate between /da/ and /ga/) in one ear and with disambiguating acoustic feature (third formant, F3) in the other ear. Multi-voxel pattern searchlight analysis was used to identify brain areas that consistently differentiated between response patterns associated with different syllable reports. By comparing responses to different stimuli with identical syllable reports and identical stimuli with different syllable reports, we disambiguated whether these regions primarily differentiated the acoustics of the stimuli or the syllable report. We found that BOLD activity patterns in left perisylvian regions (STG, SMG), left inferior frontal regions (vMC, IFG, AI), left supplementary motor cortex (SMA/pre-SMA), and right motor and somatosensory regions (M1/S1) represent listeners’ syllable report irrespective of stimulus acoustics. Most of these regions are outside of what is traditionally regarded as auditory or phonological processing areas. Our results indicate that the process of speech sound categorization implicates decision-making mechanisms and auditory-motor transformations.

Abstract

Reading Disability (RD) is often characterized by difficulties in the phonology of the language. While the molecular mechanisms underlying it are largely undetermined, loci are being revealed by genome-wide association studies (GWAS). In a previous GWAS for word reading (Price, 2020), we observed that top single-nucleotide polymorphisms (SNPs) were located near to or in genes involved in neuronal migration/axon guidance (NM/AG) or loci implicated in autism spectrum disorder (ASD). A prominent theory of RD etiology posits that it involves disturbed neuronal migration, while potential links between RD-ASD have not been extensively investigated. To improve power to identify associated loci, we up-weighted variants involved in NM/AG or ASD, separately, and performed a new Hypothesis-Driven (HD)–GWAS. The approach was applied to a Toronto RD sample and a meta-analysis of the GenLang Consortium. For the Toronto sample (n = 624), no SNPs reached significance; however, by gene-set analysis, the joint contribution of ASD-related genes passed the threshold (p~1.45 × 10–2, threshold = 2.5 × 10–2). For the GenLang Cohort (n = 26,558), SNPs in DOCK7 and CDH4 showed significant association for the NM/AG hypothesis (sFDR q = 1.02 × 10–2). To make the GenLang dataset more similar to Toronto, we repeated the analysis restricting to samples selected for reading/language deficits (n = 4152). In this GenLang selected subset, we found significant association for a locus intergenic between BTG3-C21orf91 for both hypotheses (sFDR q < 9.00 × 10–4). This study contributes candidate loci to the genetics of word reading. Data also suggest that, although different variants may be involved, alleles implicated in ASD risk may be found in the same genes as those implicated in word reading. This finding is limited to the Toronto sample suggesting that ascertainment influences genetic associations.

Abstract

The current study examined the acquisition of relative clauses (RCs) in Persian-speaking children. Persian is a relatively unique data point in crosslinguistic research in acquisition because it is a head-final language with post-nominal RCs. Children (N = 51) aged 2 to 7 years completed a picture-selection task that tested their comprehension of subject-, object-, and genitive-RCs. The results showed that the children experienced greater difficulty processing object and genitive RCs when compared to subject RCs, suggesting that the children have particular difficulty processing sentences with non-canonical word order. The results are discussed with reference to a number of theoretical accounts proposed to account for sentence difficulty.

Abstract

The authors determined the effects of changes in task demands on interpersonal and intrapersonal coordination. Participants performed a joint task in which one participant held a stick to which a circle was attached at the top (holding role), while the other held a pointer through the circle without touching its borders (pointing role). Experiment 1 investigated whether interpersonal and intrapersonal coordination varied depending on task difficulty. Results showed that interpersonal and intrapersonal coordination increased in degree and stability with increments in task difficulty. Experiment 2 explored the effects of individual constraints by increasing the balance demands of the task (one or both members of the pair stood in a less stable tandem stance). Results showed that interpersonal coordination increased in degree and stability as joint task demands increased and that coupling strength varied depending on joint and individual task constraints. In all, results suggest that interpersonal and intrapersonal coordination are affected by the nature of the task performed and the constraints it places on joint and individual performance.

Abstract

How does communicative efficiency shape language use? We approach this question by studying it at the level of the dyad, and in terms of multimodal utterances. We investigate whether and how people minimize their joint speech and gesture efforts in face-to-face interactions, using linguistic and kinematic analyses. We zoom in on other-initiated repair—a conversational microcosm where people coordinate their utterances to solve problems with perceiving or understanding. We find that efforts in the spoken and gestural modalities are wielded in parallel across repair turns of different types, and that people repair conversational problems in the most cost-efficient way possible, minimizing the joint multimodal effort for the dyad as a whole. These results are in line with the principle of least collaborative effort in speech and with the reduction of joint costs in non-linguistic joint actions. The results extend our understanding of those coefficiency principles by revealing that they pertain to multimodal utterance design.

Abstract

When people establish shared symbols for novel objects or concepts, they have been shown to rely on the use of multiple communicative modalities as well as on alignment (i.e., cross-participant repetition of communicative behavior). Yet these interactional resources have rarely been studied together, so little is known about if and how people combine multiple modalities in alignment to achieve joint reference. To investigate this, we systematically track the emergence of lexical and gestural alignment in a referential communication task with novel objects. Quantitative analyses reveal that people frequently use a combination of lexical and gestural alignment, and that such multimodal alignment tends to emerge earlier compared to unimodal alignment. Qualitative analyses of the interactional contexts in which alignment emerges reveal how people flexibly deploy lexical and gestural alignment (independently, simultaneously or successively) to adjust to communicative pressures.

Abstract

Fetal akinesia refers to a broad spectrum of disorders in which the unifying feature is a reduction or lack of fetal movement. Fetal akinesias may be caused by defects at any point along the motor system pathway including the central and peripheral nervous system, the neuromuscular junction and the muscle, as well as by restrictive dermopathy or external restriction of the fetus in utero. The fetal akinesias are clinically and genetically heterogeneous, with causative mutations identified to date in a large number of genes encoding disparate parts of the motor system. However, for most patients, the molecular cause remains unidentified. One reason for this is because the tools are only now becoming available to efficiently and affordably identify mutations in a large panel of disease genes. Next-generation sequencing offers the promise, if sufficient cohorts of patients can be assembled, to identify the majority of the remaining genes on a research basis and facilitate efficient clinical molecular diagnosis. The benefits of identifying the causative mutation(s) for each individual patient or family include accurate genetic counselling and the options of prenatal diagnosis or preimplantation genetic diagnosis.

In this review, we summarise known single-gene disorders affecting the spinal cord, peripheral nerves, neuromuscular junction or skeletal muscles that result in fetal akinesia. This audit of these known molecular and pathophysiological mechanisms involved in fetal akinesia provides a basis for improved molecular diagnosis and completing disease gene discovery.

Abstract

Vocal production learning (VPL) is the experience-driven ability to produce novel vocal signals through imitation or modification of existing vocalizations. A parallel strand of research investigates acoustic allometry, namely how information about body size is conveyed by acoustic signals. Recently, we proposed that deviation from acoustic allometry principles as a result of sexual selection may have been an intermediate step towards the evolution of vocal learning abilities in mammals. Adopting a more hypothesis-neutral stance, here we perform phylogenetic regressions and other analyses further testing a potential link between VPL and being an allometric outlier. We find that multiple species belonging to VPL clades deviate from allometric scaling but in the opposite direction to that expected from size exaggeration mechanisms. In other words, our correlational approach finds an association between VPL and being an allometric outlier. However, the direction of this association, contra our original hypothesis, may indicate that VPL did not necessarily emerge via sexual selection for size exaggeration: VPL clades show higher vocalization frequencies than expected. In addition, our approach allows us to identify species with potential for VPL abilities: we hypothesize that those outliers from acoustic allometry lying above the regression line may be VPL species. Our results may help better understand the cross-species diversity, variability and aetiology of VPL, which among other things is a key underpinning of speech in our species.

This article is part of the theme issue ‘Voice modulation: from origin and mechanism to social impact (Part II)’.

Abstract

Learning is using past experiences to inform new behaviors and actions. Because all experiences are unique, learning always requires some generalization. An effective way of improving generalization is to expose learners to more variable (and thus often more representative) input. More variability tends to make initial learning more challenging, but eventually leads to more general and robust performance. This core principle has been repeatedly rediscovered and renamed in different domains (e.g., contextual diversity, desirable difficulties, variability of practice). Reviewing this basic result as it has been formulated in different domains allows us to identify key patterns, distinguish between different kinds of variability, discuss the roles of varying task-relevant versus irrelevant dimensions, and examine the effects of introducing variability at different points in training.

Abstract

On the surface, the fields of animal communication and human linguistics have arrived at conflicting theories and conclusions with respect to the effect of social complexity on communicative complexity. For example, an increase in group size is argued to have opposite consequences on human versus animal communication systems: although an increase in human community size leads to some types of language simplification, an increase in animal group size leads to an increase in signal complexity. But do human and animal communication systems really show such a fundamental discrepancy? Our key message is that the tension between these two adjacent fields is the result of (a) a focus on different levels of analysis (namely, signal variation or grammar-like rules) and (b) an inconsistent use of terminology (namely, the terms “simple” and “complex”). By disentangling and clarifying these terms with respect to different measures of communicative complexity, we show that although animal and human communication systems indeed show some contradictory effects with respect to signal variability, they actually display essentially the same patterns with respect to grammar-like structure. This is despite the fact that the definitions of complexity and simplicity are actually aligned for signal variability, but diverge for grammatical structure. We conclude by advocating for the use of more objective and descriptive terms instead of terms such as “complexity,” which can be applied uniformly for human and animal communication systems—leading to comparable descriptions of findings across species and promoting a more productive dialogue between fields.

Abstract

An eye-tracking experiment was conducted with speakers of Dutch (N = 84, 36 male), a language that falls between grammatical and natural-gender languages. We tested whether a masculine generic pronoun causes a male bias when used in generic statements—that is, in the absence of a specific referent. We tested two types of generic statements by varying conceptual number, hypothesizing that the pronoun zijn “his” was more likely to cause a male bias with a conceptually singular than a conceptually plural ante-cedent (e.g., Someone (conceptually singular)/Everyone (conceptually plural) with perfect pitch can tune his instrument quickly). We found male participants to exhibit a male bias but with the conceptually singular antecedent only. Female participants showed no signs of a male bias. The results show that the generically intended masculine pronoun zijn “his” leads to a male bias in conceptually singular generic contexts but that this further depends on participant gender.

Abstract

Several linkage analyses implicated the chromosome 9q22 region in attention deficit/hyperactivity disorder (ADHD), a neurodevelopmental disease with remarkable persistence into adulthood. This locus contains the brain-expressed GTP-binding RAS-like 2 gene (DIRAS2) thought to regulate neurogenesis. As DIRAS2 is a positional and functional ADHD candidate gene, we conducted an association study in 600 patients suffering from adult ADHD (aADHD) and 420 controls. Replication samples consisted of 1035 aADHD patients and 1381 controls, as well as 166 families with a child affected from childhood ADHD. Given the high degree of co-morbidity with ADHD, we also investigated patients suffering from bipolar disorder (BD) (n=336) or personality disorders (PDs) (n=622). Twelve single-nucleotide polymorphisms (SNPs) covering the structural gene and the transcriptional control region of DIRAS2 were analyzed. Four SNPs and two haplotype blocks showed evidence of association with ADHD, with nominal p-values ranging from p=0.006 to p=0.05. In the adult replication samples, we obtained a consistent effect of rs1412005 and of a risk haplotype containing the promoter region (p=0.026). Meta-analysis resulted in a significant common OR of 1.12 (p=0.04) for rs1412005 and confirmed association with the promoter risk haplotype (OR=1.45, p=0.0003). Subsequent analysis in nuclear families with childhood ADHD again showed an association of the promoter haplotype block (p=0.02). rs1412005 also increased risk toward BD (p=0.026) and cluster B PD (p=0.031). Additional SNPs showed association with personality scores (p=0.008–0.048). Converging lines of evidence implicate genetic variance in the promoter region of DIRAS2 in the etiology of ADHD and co-morbid impulsive disorders.

Abstract

Temporal contrasts in speech are perceived relative to the speech rate of the surrounding context. That is, following a fast context
sentence, listeners interpret a given target sound as longer than following a slow context, and vice versa. This rate effect, often
referred to as “rate-dependent speech perception,” has been suggested to be the result of a robust, low-level perceptual process,
typically examined in quiet laboratory settings. However, speech perception often occurs in more challenging listening condi-
tions. Therefore, we asked whether rate-dependent perception would be (partially) compromised by signal degradation relative to
a clear listening condition. Specifically, we tested effects of white noise and reverberation, with the latter specifically distorting
temporal information. We hypothesized that signal degradation would reduce the precision of encoding the speech rate in the
context and thereby reduce the rate effect relative to a clear context. This prediction was borne out for both types of degradation in
Experiment 1, where the context sentences but not the subsequent target words were degraded. However, in Experiment 2, which
compared rate effects when contexts and targets were coherent in terms of signal quality, no reduction of the rate effect was
found. This suggests that, when confronted with coherently degraded signals, listeners adapt to challenging listening situations,
eliminating the difference between rate-dependent perception in clear and degraded conditions. Overall, the present study
contributes towards understanding the consequences of different types of listening environments on the functioning of low-
level perceptual processes that listeners use during speech perception.

Abstract

Three categorization experiments investigated whether the speaking rate of a preceding sentence influences durational cues to the perception of suprasegmental lexical-stress patterns. Dutch two-syllable word fragments had to be judged as coming from one of two longer words that matched the fragment segmentally but differed in lexical stress placement. Word pairs contrasted primary stress on either the first versus the second syllable or the first versus the third syllable. Duration of the initial or the second syllable of the fragments and rate of the preceding context (fast vs. slow) were manipulated. Listeners used speaking rate to decide about the degree of stress on initial syllables whether the syllables' absolute durations were informative about stress (Experiment 1a) or not (Experiment 1b). Rate effects on the second syllable were visible only when the initial syllable was ambiguous in duration with respect to the preceding rate context (Experiment 2). Absolute second syllable durations contributed little to stress perception (Experiment 3). These results suggest that speaking rate is used to disambiguate words and that rate-modulated stress cues are more important on initial than non-initial syllables. Speaking rate affects perception of suprasegmental information.

Abstract

A series of eye-tracking and categorization experiments investigated the use of speaking-rate information in the segmentation of Dutch ambiguous-word sequences. Juncture phonemes with ambiguous durations (e.g., [s] in 'eens (s)peer,' “once (s)pear,” [t] in 'nooit (t)rap,' “never staircase/quick”) were perceived as longer and hence more often as word-initial when following a fast than a slow context sentence. Listeners used speaking-rate information as soon as it became available. Rate information from a context proximal to the juncture phoneme and from a more distal context was used during on-line word recognition, as reflected in listeners' eye movements. Stronger effects of distal context, however, were observed in the categorization task, which measures the off-line results of the word-recognition process. In categorization, the amount of rate context had the greatest influence on the use of rate information, but in eye tracking, the rate information's proximal location was the most important. These findings constrain accounts of how speaking rate modulates the interpretation of durational cues during word recognition by suggesting that rate estimates are used to evaluate upcoming phonetic information continuously during prelexical speech processing.

Abstract

Human societies are built on collaborative activities. Already from early childhood, human children are skillful and proficient collaborators. They recognize when they need help in solving a problem and actively recruit collaborators [ [1] and 2 F. Warneken, F. Chen and M. Tomasello, Cooperative activities in young children and chimpanzees. Child Dev., 77 (2006), pp. 640–663. | View Record in Scopus | [MPG-SFX] | | Full Text via CrossRef | Cited By in Scopus (56) [2] ]. The societies of other primates are also to some degree cooperative. Chimpanzees, for example, engage in a variety of cooperative activities such as border patrols, group hunting, and intra- and intergroup coalitionary behavior [ [3] , [4] and [5] ]. Recent studies have shown that chimpanzees possess many of the cognitive prerequisites necessary for human-like collaboration. Chimpanzees have been shown to recognize when they need help in solving a problem and to actively recruit good over bad collaborators [ [6] and [7] ]. However, cognitive abilities might not be all that differs between chimpanzees and humans when it comes to cooperation. Another factor might be the motivation to engage in a cooperative activity. Here, we hypothesized that a key difference between human and chimpanzee collaboration—and so potentially a key mechanism in the evolution of human cooperation—is a simple preference for collaborating (versus acting alone) to obtain food. Our results supported this hypothesis, finding that whereas children strongly prefer to work together with another to obtain food, chimpanzees show no such preference.

Abstract

Acoustic allometry occurs when features of animal vocalisations can be predicted from body size measurements. Despite this being considered the norm, allometry sometimes breaks, resulting in species sounding smaller or larger than expected. A recent hypothesis suggests that allometry-breaking animals cluster into two groups: those with anatomical adaptations to their vocal tracts and those capable of learning new sounds (vocal learners). Here we test this hypothesis by probing vocal tract allometry in a proven mammalian vocal learner, the harbour seal (Phoca vitulina). We test whether vocal tract structures and body size scale allometrically in 68 individuals. We find that both body length and body weight accurately predict vocal tract length and one tracheal dimension. Independently, body length predicts vocal fold length while body weight predicts a second tracheal dimension. All vocal tract measures are larger in weaners than in pups and some structures are sexually dimorphic within age classes. We conclude that harbour seals do comply with allometric constraints, lending support to our hypothesis. However, allometry between body size and vocal fold length seems to emerge after puppyhood, suggesting that ontogeny may modulate the anatomy-learning distinction previously hypothesised as clear-cut. Species capable of producing non-allometric signals while their vocal tract scales allometrically, like seals, may then use non-morphological allometry-breaking mechanisms. We suggest that seals, and potentially other vocal learning mammals, may achieve allometry-breaking through developed neural control over their vocal organs.

Abstract

Aim and method: A comparison study of four six-year-old children attending a school with a play-based curriculum and a school with a traditionally structured classroom from low socioeconomic areas was conducted in Victoria, Australia. Children’s play, language and social skills were measured in February and again in August. At baseline assessment there was a combined sample of 31 children (mean age 5.5 years, SD 0.35 years; 13 females and 18 males). At follow-up there was a combined sample of 26 children (mean age 5.9 years, SD 0.35 years; 10 females, 16 males). Results: There was no significant difference between the school groups in play, language, social skills, age and sex at baseline assessment. Compared to norms on a standardised assessment, all the children were beginning school with delayed play ability. At follow-up assessment, children at the play-based curriculum school had made significant gains in all areas assessed (p values ranged from 0.000 to 0.05). Children at the school with the traditional structured classroom had made significant positive gains in use of symbols in play (p < 0.05) and semantic language (p < 0.05). At follow-up, there were significant differences between schools in elaborate play (p < 0.000), semantic language (p < 0.000), narrative language (p < 0.01) and social connection (p < 0.01), with children in the play-based curriculum school having significantly higher scores in play, narrative language and language and lower scores in social disconnection. Implications: Children from low SES areas begin school at risk of failure as skills in play, language and social skills are delayed. The school experience increases children’s skills, with children in the play-based curriculum showing significant improvements in all areas assessed. It is argued that a play-based curriculum meets children’s developmental and learning needs more effectively. More research is needed to replicate these results.

Abstract

The aim of this study was to examine the unique contribution of two aspects of emotion regulation (awareness and coping) to the development of internalizing problems in 11-year-old high-functioning children with an autism spectrum disorder (HFASD) and a control group, and the moderating effect of group membership on this. The results revealed overlap between the two groups, but also significant differences, suggesting a more fragmented emotion regulation pattern in children with HFASD, especially related to worry and rumination. Moreover, in children with HFASD, symptoms of depression were unrelated to positive mental coping strategies and the conviction that the emotion experience helps in dealing with the problem, suggesting that a positive approach to the problem and its subsequent emotion experience are less effective in the HFASD group.

Abstract

We present the perspective that interpersonal movement coordination results from establishing interpersonal synergies. Interpersonal synergies are higher-order control systems formed by coupling movement system degrees of freedom of two (or more) actors. Characteristic features of synergies identified in studies of intrapersonal coordination – dimensional compression and reciprocal compensation – are revealed in studies of interpersonal coordination that applied the uncontrolled manifold approach and principal component analysis to interpersonal movement tasks. Broader implications of the interpersonal synergy approach for movement science include an expanded notion of mechanism and an emphasis on interaction-dominant dynamics.

Abstract

In this study, the influence of plausibility information on the real-time processing of locally ambiguous (“garden path”) sentences in a nonnative language is investigated. Using self-paced reading, we examined how advanced Greek-speaking learners of English and native speaker controls read sentences containing temporary subject–object ambiguities, with the ambiguous noun phrase being either semantically plausible or implausible as the direct object of the immediately preceding verb. Besides providing evidence for incremental interpretation in second language processing, our results indicate that the learners were more strongly influenced by plausibility information than the native speaker controls in their on-line processing of the experimental items. For the second language learners an initially plausible direct object interpretation lead to increased reanalysis difficulty in “weak” garden-path sentences where the required reanalysis did not interrupt the current thematic processing domain. No such evidence of on-line recovery was observed, in contrast, for “strong” garden-path sentences that required more substantial revisions of the representation built thus far, suggesting that comprehension breakdown was more likely here.

Abstract

Patients with Huntington’s Disease are impaired in the recognition of emotional signals. However, the nature and extent of the impairment is controversial: It has variously been argued to be disgust-specific (Sprengelmeyer et al., 1996; 1997), general for negative emotions (Snowden, et al., 2008), or a consequence of item difficulty (Milders, Crawford, Lamb, & Simpson, 2003). Yet no study to date has included more than one positive stimulus category in emotion recognition tasks. We present a study of 14 Huntington’s patients and 15 control participants performing a forced-choice task with a range of negative and positive non-verbal emotional vocalizations. Participants were found to be impaired in emotion recognition across the emotion categories, including positive emotions such as amusement and sensual pleasure, and negative emotions, such as anger, disgust, and fear. These data complement previous work by demonstrating that impairments are found in the recognition of positive, as well as negative, emotions in Huntington’s disease. Our results point to a global deficit in the recognition of emotional signals in Huntington’s Disease.

Abstract

E. Dhooge and R. J. Hartsuiker (2010) reported experiments showing that picture naming takes longer with low- than high-frequency distractor words, replicating M. Miozzo and A. Caramazza (2003). In addition, they showed that this distractor-frequency effect disappears when distractors are masked or preexposed. These findings were taken to refute models like WEAVER++ (A. Roelofs, 2003) in which words are selected by competition. However, Dhooge and Hartsuiker do not take into account that according to this model, picture-word interference taps not only into word production but also into attentional processes. Here, the authors indicate that WEAVER++ contains an attentional mechanism that accounts for the distractor-frequency effect (A. Roelofs, 2005). Moreover, the authors demonstrate that the model accounts for the influence of masking and preexposure, and does so in a simpler way than the response exclusion through self-monitoring account advanced by Dhooge and Hartsuiker

Abstract

It has been argued that inhibition is a mechanism of attentional control in bilingual language performance. Evidence suggests that effects of inhibition are largest in the tail of a response time (RT) distribution in non-linguistic and monolingual performance domains. We examined this for bilingual performance by conducting delta-plot analyses of naming RTs. Dutch-English bilingual speakers named pictures using English while trying to ignore superimposed neutral Xs or Dutch distractor words that were semantically related, unrelated, or translations. The mean RTs revealed semantic, translation, and lexicality effects. The delta plots leveled off with increasing RT, more so when the mean distractor effect was smaller as compared with larger. This suggests that the influence of inhibition is largest toward the distribution tail, corresponding to what is observed in other performance domains. Moreover, the delta plots suggested that more inhibition was applied by high- than low-proficiency individuals in the unrelated than the other distractor conditions. These results support the view that inhibition is a domain-general mechanism that may be optionally engaged depending on the prevailing circumstances.

Abstract

E. Dhooge and R. J. Hartsuiker (2010) reported experiments showing that picture naming takes longer with low- than high-frequency distractor words, replicating M. Miozzo and A. Caramazza (2003). In addition, they showed that this distractor-frequency effect disappears when distractors are masked or preexposed. These findings were taken to refute models like WEAVER++ (A. Roelofs, 2003) in which words are selected by competition. However, Dhooge and Hartsuiker do not take into account that according to this model, picture-word interference taps not only into word production but also into attentional processes. Here, the authors indicate that WEAVER++ contains an attentional mechanism that accounts for the distractor-frequency effect (A. Roelofs, 2005). Moreover, the authors demonstrate that the model accounts for the influence of masking and preexposure, and does so in a simpler way than the response exclusion through self-monitoring account advanced by Dhooge and Hartsuiker

Abstract

When people hear words for objects with prototypical colors (e.g., ‘banana’), they look at objects of the same color (e.g., lemon), suggesting a link in comprehension between objects and their prototypical colors. However, that link does not carry over to production: The experimental record also shows that when people speak, they tend to omit prototypical colors, using color adjectives when it is informative (e.g., when referring to clothes, which have no prototypical color). These findings yield an interesting prediction, which we tested here: while prior work shows that people look at yellow objects when hearing ‘banana’, they should look away from bananas when hearing ‘yellow’. The results of an offline sentence-completion task (N = 100) and an online eye-tracking task (N = 41) confirmed that when presented with truncated color descriptions (e.g., ‘Click on the yellow…’), people anticipate clothing items rather than stereotypical fruits. A corpus analysis ruled out the possibility that this association between color and clothing arises from simple context-free co-occurrence statistics. We conclude that comprehenders make linguistic predictions based not only on what they know about the world (e.g., which objects are yellow) but also on what speakers tend to say about the world (i.e., what content would be informative).

Abstract

In this article, we provide the first quantitative account of the frequent use of embedding in Shawi, a Kawapanan language spoken in Peruvian Northwestern Amazonia. We collected a corpus of ninety-two Frog Stories (Mayer 1969) from three different field sites in 2015 and 2016. Using the glossed corpus as our data, we conducted a generalised mixed model analysis, where we predicted the use of embedding with several macrosocial variables, such as gender, age, and education level. We show that bilingualism (Amazonian Spanish-Shawi) and education, mostly restricted by complex gender differences in Shawi communities, play a significant role in the establishment of linguistic preferences in narration. Moreover, we argue that the use of embedding reflects the impact of the mestizo1 society from the nineteenth century until today in Santa Maria de Cahuapanas, reshaping not only Shawi demographics but also linguistic practices

Abstract

The present work investigated young children’s normative understanding of property rights using a novel methodology. Two- and 3-year-old children participated in situations in which an actor (1) took possession of an object for himself, and (2) attempted to throw it away. What varied was who owned the object: the actor himself, the child subject, or a third party. We found that while both 2- and 3-year-old children protested frequently when their own object was involved, only 3-year-old children protested more when a third party’s object was involved than when the actor was acting on his own object. This suggests that at the latest around 3 years of age young children begin to understand the normative dimensions of property rights.

Abstract

Spoken word recognition is achieved via competition between activated lexical candidates that match the incoming speech input. The competition is modulated by prelexical cues that are important for segmenting the auditory speech stream into linguistic units. One such prelexical cue that listeners rely on in spoken word recognition is phonotactics. Phonotactics defines possible combinations of phonemes within syllables or words in a given language. The present study aimed at investigating both temporal and topographical aspects of the neuronal correlates of phonotactic processing by simultaneously applying event-related brain potentials (ERPs) and functional near-infrared spectroscopy (fNIRS). Pseudowords, either phonotactically legal or illegal with respect to the participants' native language, were acoustically presented to passively listening adult native German speakers. ERPs showed a larger N400 effect for phonotactically legal compared to illegal pseudowords, suggesting stronger lexical activation mechanisms in phonotactically legal material. fNIRS revealed a left hemispheric network including fronto-temporal regions with greater response to phonotactically legal pseudowords than to illegal pseudowords. This confirms earlier hypotheses on a left hemispheric dominance of phonotactic processing most likely due to the fact that phonotactics is related to phonological processing and represents a segmental feature of language comprehension. These segmental linguistic properties of a stimulus are predominantly processed in the left hemisphere. Thus, our study provides first insights into temporal and topographical characteristics of phonotactic processing mechanisms in a passive listening task. Differential brain responses between known and unknown phonotactic rules thus supply evidence for an implicit use of phonotactic cues to guide lexical activation mechanisms.

Abstract

Herein, we contextualize, problematize, and offer some insights for moving beyond the problem of monolingual comparative normativity in (psycho) linguistic research on bilingualism. We argue that, in the vast majority of cases, juxtaposing (functional) monolinguals to bilinguals fails to offer what the comparison is supposedly intended to do: meet the standards of empirical control in line with the scientific method. Instead, the default nature of monolingual comparative normativity has historically contributed to inequalities in many facets of bilingualism research and continues to impede progress on multiple levels. Beyond framing our views on the matter, we offer some epistemological considerations and methodological alternatives to this standard practice that improve empirical rigor while fostering increased diversity, inclusivity, and equity in our field.

Abstract

Research has demonstrated that young children quickly acquire knowledge of how the structure of their language encodes meaning. However, this work focused on structurally simple transitives. The present studies investigate childrens' comprehension of the double object dative (e.g., I gave him the box) and the prepositional dative (e.g., I gave the box to him). In Study 1, 3- and 4-year-olds correctly preferred a transfer event reading of prepositional datives with novel verbs (e.g., I'm glorping the rabbit to the duck) but were unable to interpret double object datives (e.g., I'm glorping the duck the rabbit). In Studies 2 and 3, they were able to interpret both dative types when the nouns referring to the theme and recipient were canonically marked (Study 2; I'm glorping the rabbit to Duck) and, to a lesser extent, when they were distinctively but noncanonically marked (Study 3: I'm glorping rabbit to the Duck). Overall, the results suggest that English children have some verb-general knowledge of how dative syntax encodes meaning by 3 years of age, but successful comprehension may require the presence of additional surface cues.

Abstract

In the Dot task, children and adults involuntarily compute an avatar’s visual perspective, which has been interpreted by some as automatic Theory of Mind. This interpretation has been challenged by other researchers arguing that the task reveals automatic attentional orienting. Here we tested a new interpretation of previous findings: the seemingly automatic processes revealed by the Dot task result from the high Executive Control demands of this verification paradigm, which taxes short-term memory and imposes perspective-switching costs. We tested this hypothesis in three experiments conducted in India with newly sighted children (Experiment 1; N = 5; all girls), neurotypical children (Experiment 2; ages 5–10; N = 90; 38 girls) and adults (Experiment 3; N = 30; 18 women) in a highly simplified version of the Dot task. No evidence of automatic perspective-taking was observed, although all groups revealed perspective-taking costs. A newly sighted child and the youngest children in our sample also showed an egocentric bias, which disappeared by age 10, confirming that visual perspective taking develops during the school years. We conclude that the standard Dot task imposes such methodological demands on both children and adults that the alleged evidence of automatic processes (either mindreading or domain general) may simply reveal limitations in Executive Control.

Abstract

In referential communication, gaze is often interpreted as a social cue that facilitates comprehension and enables word learning. Here we investigated the degree to which head turning facilitates gaze following. We presented participants with static pictures of a man looking at a target object in a first and third block of trials (pre- and post-intervention), while they saw short videos of the same man turning towards the target in the second block of trials (intervention). In Experiment 1, newly sighted individuals (treated for congenital cataracts; N = 8) benefited from the motion cues, both when comparing their initial performance with static gaze cues to their performance with dynamic head turning, and their performance with static cues before and after the videos. In Experiment 2, neurotypical school children (ages 5–10 years; N = 90) and adults (N = 30) also revealed improved performance with motion cues, although most participants had started to follow the static gaze cues before they saw the videos. Our results confirm that head turning is an effective social cue when interpreting new words, offering new insights for a pathways approach to development.

Abstract

Previous research has pointed at communicative efficiency as a possible constraint on language structure. Here we investigated adjective position in American Sign Language (ASL), a language with relatively flexible word order, to test the incremental efficiency hypothesis, according to which both speakers and signers try to produce efficient referential expressions that are sensitive to the word order of their languages. The results of three experiments using a standard referential communication task confirmed that deaf ASL signers tend to produce absolute adjectives, such as color or material, in prenominal position, while scalar adjectives tend to be produced in prenominal position when expressed as lexical signs, but in postnominal position when expressed as classifiers. Age of ASL exposure also had an effect on referential choice, with early-exposed signers producing more classifiers than late-exposed signers, in some cases. Overall, our results suggest that linguistic, pragmatic and developmental factors affect referential choice in ASL, supporting the hypothesis that communicative efficiency is an important factor in shaping language structure and use.

Abstract

This study explores the connection between language and social cognition by empirically testing different typological analyses of various demonstrative systems. Linguistic typology classifies demonstrative systems as distance-oriented or person-oriented, depending on whether they indicate the location of a referent relative only to the speaker, or to both the speaker and the listener. From the perspective of social cognition, speakers of languages with person-oriented systems must monitor their listener’s spatial location in order to accurately use their demonstratives, while speakers of languages with distance-oriented systems can use demonstratives from their own, egocentric perspective. Resolving an ongoing controversy around the nature of the Spanish demonstrative system, the results of Experiment 1 confirmed that this demonstrative system is person oriented, while the English system is distance oriented. Experiment 2 revealed that not all three-way demonstrative systems are person oriented, with Japanese speakers showing sensitivity to the listener’s spatial location, while Turkish speakers did not show such an effect in their demonstrative choice. In Experiment 3, Catalan-Spanish bilinguals showed sensitivity to listener position in their choice of the Spanish distal form, but not in their choice of the medial form. These results were interpreted as a transfer effect from Catalan, which revealed analogous results to English. Experiment 4 investigated the use of demonstratives to redirect a listener’s attention to the intended referent, which is a universal function of demonstratives that also hinges on social cognition. Japanese and Spanish speakers chose between their proximal and distal demonstratives flexibly, depending on whether the listener was looking closer or further from the referent, whereas Turkish speakers chose their medial form for attention correction. In conclusion, the results of this study support the view that investigating how speakers of different languages jointly use language and social cognition in communication has the potential to unravel the deep connection between these two fundamentally human capacities.

Abstract

Economic inequality is associated with preferences for smaller, immediate gains over larger, delayed ones. Such temporal discounting may feed into rising global inequality, yet it is unclear whether it is a function of choice preferences or norms, or rather the absence of sufficient resources for immediate needs. It is also not clear whether these reflect true differences in choice patterns between income groups. We tested temporal discounting and five intertemporal choice anomalies using local currencies and value standards in 61 countries (N = 13,629). Across a diverse sample, we found consistent, robust rates of choice anomalies. Lower-income groups were not significantly different, but economic inequality and broader financial circumstances were clearly correlated with population choice patterns.

Abstract

In a data set of 291 spontaneous utterances from German 5-year-olds, 7-year-olds and adults, nuclear pitch contours were labeled manually using the GToBI annotation system. Ten different contour types were identified. The fundamental frequency (F0) of these contours was modeled using third-order orthogonal polynomials, following an approach similar to the one Grabe, Kochanski, and Coleman (2007) used for English. Statistical analyses showed that all but one contour pair differed significantly from each other in at least one of the four coefficients. This demonstrates that polynomial modeling can provide quantitative empirical support for phonological labels in unscripted speech, and for languages other than English. Furthermore, polynomial expressions can be used to derive the alignment of tonal targets relative to the syllable structure, making polynomial modeling more accessible to the phonological research community. Finally, within-contour comparisons of the three age groups showed that for children, the magnitude of the higher coefficients is lower, suggesting that they are not yet able to modulate their pitch as fast as adults.

Abstract

Background: A well-known test for measuring verbal adequacy (i.e., verbal effectiveness) in mildly impaired aphasic speakers is the Amsterdam-Nijmegen Everyday Language Test (ANELT; Blomert, Koster, & Kean, 1995). Aphasia therapy practitioners score verbal adequacy qualitatively when they administer the ANELT to their aphasic clients in clinical practice. Aims: The current study investigated whether the construct validity of the ANELT could be further improved by substituting the qualitative score by a quantitative one, which takes the number of essential information units into account. The new quantitative measure could have the following advantages: the ability to derive a quantitative score of verbal efficiency, as well as improved sensitivity to detect changes in functional communication over time. Methods & Procedures: The current study systematically compared a new quantitative measure of verbal effectiveness with the current ANELT Comprehensibility scale, which is based on qualitative judgements. A total of 30 speakers of Dutch participated: 20 non-aphasic speakers and 10 aphasic patients with predominantly expressive disturbances. Outcomes & Results: Although our findings need to be replicated in a larger group of aphasic speakers, the main results suggest that the new quantitative measure of verbal effectiveness is more sensitive to detect change in verbal effectiveness over time. What is more, it can be used to derive a measure of verbal efficiency. Conclusions: The fact that both verbal effectiveness and verbal efficiency can be reliably as well as validly measured in the ANELT is of relevance to clinicians. It allows them to obtain a more complete picture of aphasic speakers' functional communication skills.

Abstract

Two cross-linguistic experiments comparing musicians and non-musicians were performed in order to examine whether musicians have enhanced perception of specific acoustical features of speech in a second language (L2). These discrimination and identification experiments examined the perception of various speech features; namely, the timing and quality of Japanese consonants, and the quality of Dutch vowels. We found that musical experience was more strongly associated with discrimination performance rather than identification performance. The enhanced perception was observed not only with respect to L2, but also L1. It was most pronounced when tested with Japanese consonant timing. These findings suggest the following: 1) musicians exhibit enhanced early acoustical analysis of speech, 2) musical training does not equally enhance the perception of all acoustic features automatically, and 3) musicians may enjoy an advantage in the perception of acoustical features that are important in both language and music, such as pitch and timing. Research Highlights We compared the perception of L1 and L2 speech by musicians and non-musicians. Discrimination and identification experiments examined perception of consonant timing, quality of Japanese consonants and of Dutch vowels. We compared results for Japanese native musicians and non-musicians as well as, Dutch native musicians and non-musicians. Musicians demonstrated enhanced perception for both L1 and L2. Most pronounced effect was found for Japanese consonant timing.

Abstract

To convey meaning, human language relies on hierarchically organized, long-
range relationships spanning words, phrases, sentences and discourse. As the
distances between elements (e.g. phonemes, characters, words) in human
language sequences increase, the strength of the long-range relationships
between those elements decays following a power law. This power-law
relationship has been attributed variously to long-range sequential organiz-
ation present in human language syntax, semantics and discourse structure.
However, non-linguistic behaviours in numerous phylogenetically distant
species, ranging from humpback whale song to fruit fly motility, also demon-
strate similar long-range statistical dependencies. Therefore, we hypothesized
that long-range statistical dependencies in human speech may occur indepen-
dently of linguistic structure. To test this hypothesis, we measured long-range
dependencies in several speech corpora from children (aged 6 months–
12 years). We find that adult-like power-law statistical dependencies are present
in human vocalizations at the earliest detectable ages, prior to the production of
complex linguistic structure. These linguistic structures cannot, therefore, be
the sole cause of long-range statistical dependencies in language

Abstract

In recent decades, the amount of marine debris has increased in our oceans. As wildlife interactions with debris increase, so does the number of entangled animals, impairing normal behavior and potentially affecting the survival of these individuals. The current study summarizes data on two phocid species, harbor (Phoca vitulina) and gray seals (Halichoerus grypus), affected by marine debris in Dutch waters from 2010 to 2020. The findings indicate that the annual entanglement rate (13.2 entanglements/year) has quadrupled compared with previous studies. Young seals, particularly gray seals, are the most affected individuals, with most animals found or sighted with fishing nets wrapped around their necks. Interestingly, harbor seals showed a higher incidence of ingested debris. Species differences with regard to behavior, foraging strategies, and habitat preferences may explain these findings. The lack of consistency across reports suggests that it is important to standardize data collection from now on. Despite increased public awareness about the adverse environmental effects of marine debris, more initiatives and policies are needed to ensure the protection of the marine environment in the Netherlands.

Abstract

Three- and four-year-old children were asked predicate-focus questions ('What's X doing?') about a scene in which an agent performed an action on a patient. We varied: (i) whether (or not) the preceding discourse context, which established the patient as given information, was available for the questioner; and (ii) whether (or not) the patient was perceptually available to the questioner when she asked the question. The main finding in our study differs from those of previous studies since it suggests that children are sensitive to the perceptual context at an earlier age than they are to previous discourse context if they need to take the questioner's perspective into account. Our finding indicates that, while children are in principle sensitive to both factors, young children rely on perceptual availability when a conflict arises.

Abstract

Attention-deficit hyperactivity disorder (ADHD) is a common behavioral disorder affecting about 4–8% of children. ADHD persists into adulthood in around 65% of cases, either as the full condition or in partial remission with persistence of symptoms. Pharmacological, animal and molecular genetic studies support a role for genes of the dopaminergic system in ADHD due to its essential role in motor control, cognition, emotion, and reward. Based on these data, we analyzed two functional polymorphisms within the DRD4 gene (120 bp duplication in the promoter and 48 bp VNTR in exon 3) in a clinical sample of 1,608 adult ADHD patients and 2,352 controls of Caucasian origin from four European countries that had been recruited in the context of the International Multicentre persistent ADHD CollaboraTion (IMpACT). Single-marker analysis of the two polymorphisms did not reveal association with ADHD. In contrast, multiple-marker meta-analysis showed a nominal association (P  = 0.02) of the L-4R haplotype (dup120bp-48bpVNTR) with adulthood ADHD, especially with the combined clinical subtype. Since we previously described association between adulthood ADHD and the dopamine transporter SLC6A3 9R-6R haplotype (3′UTR VNTR-intron 8 VNTR) in the same dataset, we further tested for gene × gene interaction between DRD4 and SLC6A3. However, we detected no epistatic effects but our results rather suggest additive effects of the DRD4 risk haplotype and the SLC6A3 gene.

Abstract

Does our perception of others’ emotional signals depend on the language we speak or is our perception the same regardless of language and culture? It is well established that human emotional facial expressions are perceived categorically by viewers, but whether this is driven by perceptual or linguistic mechanisms is debated. We report an investigation into the perception of emotional facial expressions, comparing German speakers to native speakers of Yucatec Maya, a language with no lexical labels that distinguish disgust from anger. In a free naming task, speakers of German, but not Yucatec Maya, made lexical distinctions between disgust and anger. However, in a delayed match-to-sample task, both groups perceived emotional facial expressions of these and other emotions categorically. The magnitude of this effect was equivalent across the language groups, as well as across emotion continua with and without lexical distinctions. Our results show that the perception of affective signals is not driven by lexical labels, instead lending support to accounts of emotions as a set of biologically evolved mechanisms.

Abstract

In the current study we use electroencephalography (EEG) to detect heard music from the brain signal, hypothesizing that the time structure in music makes it especially suitable for decoding perception from EEG signals. While excluding music with vocals, we classified the perception of seven different musical fragments of about three seconds, both individually and cross-participants, using only time domain information (the event-related potential, ERP). The best individual results are 70% correct in a seven-class problem while using single trials, and when using multiple trials we achieve 100% correct after six presentations of the stimulus. When classifying across participants, a maximum rate of 53% was reached, supporting a general representation of each musical fragment over participants. While for some music stimuli the amplitude envelope correlated well with the ERP, this was not true for all stimuli. Aspects of the stimulus that may contribute to the differences between the EEG responses to the pieces of music are discussed.

Abstract

This paper explores the use of demonstratives in non-embedded clausal nominalisations. We present data and analysis from three Papuan languages of the Timor-Alor-Pantar family in south-east Indonesia. In these languages, demonstratives can apply to the clausal as well as to the nominal domain, contributing contrastive semantic content in assertive stance-taking and attention-directing utterances. In the Timor-Alor-Pantar constructions, meanings that are to do with spatial and discourse locations at the participant level apply to spatial, temporal and mental locations at the state or event leve

Abstract

Work on animals indicates that BOLD is preferentially sensitive to local field potentials, and that it correlates most strongly with gamma band neuronal synchronization. Here we investigate how the BOLD signal in humans performing a cognitive task is related to neuronal synchronization across different frequency bands. We simultaneously recorded EEG and BOLD while subjects engaged in a visual attention task known to induce sustained changes in neuronal synchronization across a wide range of frequencies. Trial-by-trial BOLD luctuations correlated positively with trial-by-trial fluctuations in high-EEG gamma power (60–80 Hz) and negatively with alpha and beta power. Gamma power on the one hand, and alpha and beta power on the other hand, independently contributed to explaining BOLD variance. These results indicate that the BOLD-gamma coupling observed in animals can be extrapolated to humans performing a task and that neuronal dynamics underlying high- and low-frequency synchronization contribute independently to the BOLD signal.

Abstract

This study examines the placement of finite and nonfinite lexical verbs and finite light verbs (LVs) in semispontaneous production and elicited imitation of adult beginning learners of German and French. Theories assuming nonnativelike syntactic representations at early stages of development predict variable placement of lexical verbs and consistent placement of LVs, whereas theories assuming nativelike syntax predict variability for nonfinite verbs and consistent placement of all finite verbs. The results show that beginning learners of German have consistent preferences only for LVs. More advanced learners of German and learners of French produce and imitate finite verbs in more variable positions than nonfinite verbs. This is argued to support a structure-building view of second-language development.

Abstract

Many mental health conditions present a spectrum of social difficulties that overlaps with social behaviour in the general population including shared but little characterised genetic links. Here, we systematically investigate heterogeneity in shared genetic liabilities with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorders (ASD), bipolar disorder (BP), major depression (MD) and schizophrenia across a spectrum of different social symptoms. Longitudinally assessed low-prosociality and peer-problem scores in two UK population-based cohorts (4–17 years; parent- and teacher-reports; Avon Longitudinal Study of Parents and Children(ALSPAC): N ≤ 6,174; Twins Early Development Study(TEDS): N ≤ 7,112) were regressed on polygenic risk scores for disorder, as informed by genome-wide summary statistics from large consortia, using negative binomial regression models. Across ALSPAC and TEDS, we replicated univariate polygenic associations between social behaviour and risk for ADHD, MD and schizophrenia. Modelling variation in univariate genetic effects jointly using random-effect meta-regression revealed evidence for polygenic links between social behaviour and ADHD, ASD, MD, and schizophrenia risk, but not BP. Differences in age, reporter and social trait captured 45–88% in univariate effect variation. Cross-disorder adjusted analyses demonstrated that age-related heterogeneity in univariate effects is shared across mental health conditions, while reporter- and social trait-specific heterogeneity captures disorder-specific profiles. In particular, ADHD, MD, and ASD polygenic risk were more strongly linked to peer problems than low prosociality, while schizophrenia was associated with low prosociality only. The identified association profiles suggest differences in the social genetic architecture across mental disorders when investigating polygenic overlap with population-based social symptoms spanning 13 years of child and adolescent development.

Abstract

Direct objects in Dutch can precede or follow adverbs, a phenomenon commonly referred to as scrambling. The linguistic literature agrees in its assumption that scrambling is regulated by the topicality and anaphoricity status of definite objects, but theories vary as to what kinds of objects exactly are predicted to scramble. This study reports experimental data from a sentence completion experiment with adult native speakers of Dutch, showing that topics are scrambled more often than foci, and that anaphoric objects are scrambled more often than non-anaphoric objects. However, while the data provide support for the assumption that topicality and anaphoricity play an important role in scrambling, they also indicate that the discourse status of the object in and of itself cannot explain the full scrambling variation.

Abstract

Studying the interaction between brain regions is important to increase our understanding of brain function. Magnetoencephalography (MEG) is well suited to investigate brain connectivity, because it provides measurements of activity of the whole brain at very high temporal resolution. Typically, brain activity is reconstructed from the sensor recordings with an inverse method such as a beamformer, and subsequently a connectivity metric is estimated between predefined reference regions-of-interest (ROIs) and the rest of the source space. Unfortunately, this approach relies on a robust estimate of the relevant reference regions and on a robust estimate of the activity in those reference regions, and is not generally applicable to a wide variety of cognitive paradigms. Here, we investigate the possibility to perform all-to-all pairwise connectivity analysis, thus removing the need to define ROIs. Particularly, we evaluate the effect of nonhomogeneous spatial smoothing of differential connectivity maps. This approach is inspired by the fact that the spatial resolution of source reconstructions is typically spatially nonhomogeneous. We use this property to reduce the spatial noise in the cerebro-cerebral connectivity map, thus improving interpretability. Using extensive data simulations we show a superior detection rate and a substantial reduction in the number of spurious connections. We conclude that nonhomogeneous spatial smoothing of cerebro-cerebral connectivity maps could be an important improvement of the existing analysis tools to study neuronal interactions noninvasively.

Abstract

Local groups of neurons engaged in a cognitive task often exhibit rhythmically synchronized activity in the gamma band, a phenomenon that likely enhances their impact on downstream areas. The efficacy of neuronal interactions may be enhanced further by interareal synchronization of these local rhythms, establishing mutually well timed fluctuations in neuronal excitability. This notion suggests that long-range synchronization is enhanced selectively for connections that are behaviorally relevant. We tested this prediction in the human motor system, assessing activity from bilateral motor cortices with magnetoencephalography and corresponding spinal activity through electromyography of bilateral hand muscles. A bimanual isometric wrist extension task engaged the two motor cortices simultaneously into interactions and coherence with their respective corresponding contralateral hand muscles. One of the hands was cued before each trial as the response hand and had to be extended further to report an unpredictable visual go cue. We found that, during the isometric hold phase, corticomuscular coherence was enhanced, spatially selective for the corticospinal connection that was effectuating the subsequent motor response. This effect was spectrally selective in the low gamma-frequency band (40–47 Hz) and was observed in the absence of changes in motor output or changes in local cortical gamma-band synchronization. These findings indicate that, in the anatomical connections between the cortex and the spinal cord, gamma-band synchronization is a mechanism that may facilitate behaviorally relevant interactions between these distant neuronal groups.

Abstract

Aging appears to impair the ability to adapt speech and gestures based on knowledge shared with an addressee
(common ground-based recipient design) in narrative settings. Here, we test whether this extends to spatial settings
and is modulated by cognitive abilities. Younger and older adults gave instructions on how to assemble 3D-
models from building blocks on six consecutive trials. We induced mutually shared knowledge by either
showing speaker and addressee the model beforehand, or not. Additionally, shared knowledge accumulated
across the trials. Younger and crucially also older adults provided recipient-designed utterances, indicated by a
significant reduction in the number of words and of gestures when common ground was present. Additionally, we
observed a reduction in semantic content and a shift in cross-modal distribution of information across trials.
Rather than age, individual differences in verbal and visual working memory and semantic fluency predicted the
extent of addressee-based adaptations. Thus, in spatial tasks, individual cognitive abilities modulate the inter-
active language use of both younger and older adul

Abstract

In spontaneous, conversational speech, words are often reduced compared to their citation forms, such that a word like yesterday may sound like [’jεsmall eshei]. The present chapter investigates such acoustic reduction. The study of reduction needs large corpora that are transcribed phonetically. The first part of this chapter describes an automatic transcription procedure used to obtain such a large phonetically transcribed corpus of Dutch spontaneous dialogues, which is subsequently used for the investigation of acoustic reduction. First, the orthographic transcriptions were adapted for automatic processing. Next, the phonetic transcription of the corpus was created by means of a forced alignment using a lexicon with multiple pronunciation variants per word. These variants were generated by applying phonological and reduction rules to the canonical phonetic transcriptions of the words. The second part of this chapter reports the results of a quantitative analysis of reduction in the corpus on the basis of the generated transcriptions and gives an inventory of segmental reductions in standard Dutch. Overall, we found that reduction is more pervasive in spontaneous Dutch than previously documented.

Abstract

Speakers tend to repeat syntactic structures across sentences, a phenomenon called syntactic priming. Although it has been suggested that repeating syntactic structures should result in speeded responses, previous research has focused on effects in response tendencies. We investigated syntactic priming effects simultaneously in response tendencies and response latencies for active and passive transitive sentences in a picture description task. In Experiment 1, there were priming effects in response tendencies for passives and in response latencies for actives. However, when participants' pre-existing preference for actives was altered in Experiment 2, syntactic priming occurred for both actives and passives in response tendencies as well as in response latencies. This is the first investigation of the effects of structure frequency on both response tendencies and latencies in syntactic priming. We discuss the implications of these data for current theories of syntactic processing.

Abstract

The present study investigates the functions of gestures in preschoolers’ descriptions of activities. Specifically, utilizing McNeill’s growth point theory (1992), I examine how gestures contribute to the creation of contrast from the immediate context in the spoken discourse of children. When preschool children describe an activity consisting of multiple actions, like playing on a slide, they often begin with the central action (e.g., sliding-down) instead of with the beginning of the activity sequence (e.g., climbing-up). This study indicates that, in descriptions of activities, gestures may be among the cues the speaker uses for forming a next idea or for repairing the temporal order of the activities described. Gestures may function for the speaker as visual feedback and contribute to the process of utterance formation and provide an index for assessing language development.

Abstract

How stable is the lexicon for perceptual experiences? This article presents results on how the Trobriand Islanders of Papua New Guinea talk about color and taste and whether this has changed over the years. Comparing the results of research on color terms conducted in 1983 with data collected in 2008 revealed that many English color terms have been integrated into the Kilivila lexicon. Members of the younger generation with school education have been the agents of this language change. However, today not all English color terms are produced correctly according to English lexical semantics. The traditional Kilivila color terms bwabwau ‘black’, pupwakau ‘white’, and bweyani ‘red’ are not affected by this change, probably because of the cultural importance of the art of coloring canoes, big yams houses, and bodies. Comparing the 1983 data on taste vocabulary with the results of my 2008 research revealed no substantial change. The conservatism of the Trobriand Islanders' taste vocabulary may be related to the conservatism of their palate. Moreover, they are more interested in displaying and exchanging food than in savoring it. Although English color terms are integrated into the lexicon, Kilivila provides evidence that traditional terms used for talking about color and terms used to refer to tastes have remained stable over time.

Abstract

Without Abstract

Abstract

Small average differences in the left-right asymmetry of cerebral cortical thickness have been reported in individuals with autism spectrum disorder (ASD) compared to typically developing controls, affecting widespread cortical regions. The possible impacts of these regional alterations in terms of structural network effects have not previously been characterized. Inter-regional morphological covariance analysis can capture network connectivity between different cortical areas at the macroscale level. Here, we used cortical thickness data from 1455 individuals with ASD and 1560 controls, across 43 independent datasets of the ENIGMA consortium’s ASD Working Group, to assess hemispheric asymmetries of intra-individual structural covariance networks, using graph theory-based topological metrics. Compared with typical features of small-world architecture in controls, the ASD sample showed significantly altered average asymmetry of networks involving the fusiform, rostral middle frontal, and medial orbitofrontal cortex, involving higher randomization of the corresponding right-hemispheric networks in ASD. A network involving the superior frontal cortex showed decreased right-hemisphere randomization. Based on comparisons with meta-analyzed functional neuroimaging data, the altered connectivity asymmetry particularly affected networks that subserve executive functions, language-related and sensorimotor processes. These findings provide a network-level characterization of altered left-right brain asymmetry in ASD, based on a large combined sample. Altered asymmetrical brain development in ASD may be partly propagated among spatially distant regions through structural connectivity.

Abstract

Speakers use vocabulary for spatial verticality and size to describe pitch. A high–low contrast is common to many languages, but others show contrasts like thick–thin and big–small. We consider uses of thick for low pitch and thin for high pitch in three languages: Farsi, Turkish, and Zapotec. We ask how metaphors for pitch structure the sound space. In a language like English, high applies to both high-pitched as well as high-amplitude (loud) sounds; low applies to low-pitched as well as low-amplitude (quiet) sounds. Farsi, Turkish, and Zapotec organize sound in a different way. Thin applies to high pitch and low amplitude and thick to low pitch and high amplitude. We claim that these metaphors have their sources in life experiences. Musical instruments show co-occurrences of higher pitch with thinner, smaller objects and lower pitch with thicker, larger objects. On the other hand bodily experience can ground the high–low metaphor. A raised larynx produces higher pitch and lowered larynx lower pitch. Low-pitched sounds resonate the chest, a lower place than highpitched sounds. While both patterns are available from life experience, linguistic experience privileges one over the other, which results in differential structuring of the multiple dimensions of sound.

Abstract

Understanding language semantically related to actions activates the motor cortex. This activation is sensitive to semantic information such as the body part used to perform the action (e.g. arm-/leg-related action words). Additionally, motor movements of the hands/feet can have a causal effect on memory maintenance of action words, suggesting that the involvement of motor systems extends to working memory. This study examined brain correlates of verbal memory load for action-related words using event-related fMRI. Seventeen participants saw either four identical or four different words from the same category (arm-/leg-related action words) then performed a nonmatching-to-sample task. Results show that verbal memory maintenance in the high-load condition produced greater activation in left premotor and supplementary motor cortex, along with posterior-parietal areas, indicating that verbal memory circuits for action-related words include the cortical action system. Somatotopic memory load effects of arm- and leg-related words were observed, but only at more anterior cortical regions than was found in earlier studies employing passive reading tasks. These findings support a neurocomputational model of distributed action-perception circuits (APCs), according to which language understanding is manifest as full ignition of APCs, whereas working memory is realized as reverberant activity receding to multimodal prefrontal and lateral temporal areas.

Abstract

We investigated the effect of optionality on the acquisition of new/given markers, with a special focus on grammaticalization as a stage of optional use of the emerging form. To this end, we conducted a narrative-elicitation task with 5-year-old children and adults across four typologically-distinct languages with different new/given markers: English, Hindi, Mandinka and Spanish. Our starting assumption was that the Hindi numeral ‘ek’ (one) is developing into an indefinite article, which should delay children’s acquisition because of its optional use to introduce discourse referents. Supporting the Optionality Hypothesis, Experiment 1 revealed that obligatory markers are acquired earlier than optional markers. Experiment 2 focused on Hindi and showed that 10-year-old children’s use of ‘ek’ to introduce discourse characters was higher than 5-year-olds’ and comparable to adults’, replicating this pattern of results in two different cities in Northern India. Lastly, a follow-up study showed that Mandinka-speaking children and adults made use of all available discourse markers when tested on a familiar story, rather than with pictorial prompts, highlighting the importance of using culturally-appropriate methods of narrative elicitation in cross-linguistic research. We conclude by discussing the implications of article grammaticalization for common ground management in a speech community.