Publications

Displaying 301 - 400 of 711
  • Klein, W. (1997). Nobels Vermächtnis, oder die Wandlungen des Idealischen. Zeitschrift für Literaturwissenschaft und Linguistik, 107, 6-18.

    Abstract

    Nobel's legacy, or the metamorphosis of what is idealistic Ever since the first Nobel prize in literature was awarded to Prudhomme in 1901, the decisions of the Swedish Academy have been subject to criticism. What is surprising in the changing decision policy as well as in its criticism is the fact that Alfred Nobel's original intentions are hardly ever taken into account: the Nobel prize is a philanthropic prize, it is not meant to select and honour the most eminent literary work but the work with maximal benefit to human beings. What is even more surprising is the fact that no one seems to care that the donator's Last Will is regularly broken.
  • Klein, W. (1982). Pronoms personnels et formes d'acquisition. Encrages, 8/9, 42-46.
  • Klein, W. (Ed.). (1997). Technologischer Wandel in den Philologien [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (106).
  • Klein, W., & Perdue, C. (1997). The basic variety (or: Couldn't natural languages be much simpler?). Second Language Research, 13, 301-347. doi:10.1191/026765897666879396.

    Abstract

    In this article, we discuss the implications of the fact that adult second language learners (outside the classroom) universally develop a well-structured, efficient and simple form of language–the Basic Variety (BV). Three questions are asked as to (1) the structural properties of the BV, (2) the status of these properties and (3) why some structural properties of ‘fully fledged’ languages are more complex. First, we characterize the BV in four respects: its lexical repertoire, the principles according to which utterances are structured, and temporality and spatiality expressed. The organizational principles proposed are small in number, and interact. We analyse this interaction, describing how the BV is put to use in various complex verbal tasks, in order to establish both what its communicative potentialities are, and also those discourse contexts where the constraints come into conflict and where the variety breaks down. This latter phenomenon provides a partial answer to the third question,concerning the relative complexity of ‘fully fledged’ languages–they have devices to deal with such cases. As for the second question, it is argued firstly that the empirically established continuity of the adult acquisition process precludes any assignment of the BV to a mode of linguistic expression (e.g., ‘protolanguage’) distinct from that of ‘fully fledged’ languages and, moreover, that the organizational constraints of the BV belong to the core attributes of the human language capacity, whereas a number of complexifications not attested in the BV are less central properties of this capacity. Finally, it is shown that the notion of feature strength, as used in recent versions of Generative Grammar, allows a straightforward characterization of the BV as a special case of an I-language, in the sense of this theory. Under this perspective, the acquisition of an Ilanguage beyond the BV can essentially be described as a change in feature strength.
  • Klein, W. (Ed.). (2000). Sprache des Rechts [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (118).
  • Klein, W., & Berliner Arbeitsgruppe (2000). Sprache des Rechts: Vermitteln, Verstehen, Verwechseln. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (118), 7-33.
  • Klein, W. (Ed.). (1986). Sprachverfall [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (62).
  • Klein, W. (2000). Was uns die Sprache des Rechts über die Sprache sagt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (118), 115-149.
  • Klein, W. (1999). Wie sich das deutsche Perfekt zusammensetzt. Zeitschrift für Literaturwissenschaft und Linguistik; Metzler, Stuttgart, (113), 52-85.
  • Klein, W. (Ed.). (1982). Zweitspracherwerb [Special Issue]. Zeitschrift für Literaturwissenschaft und Linguistik, (45).
  • Klein, W. (1986). Über Ansehen und Wirkung der deutschen Sprachwissenschaft heute. Linguistische Berichte, 100, 511-520.
  • Knösche, T. R., & Bastiaansen, M. C. M. (2001). Does the Hilbert transform improve accuracy and time resolution of ERD/ERS? Biomedizinische Technik, 46(2), 106-108.
  • Kochari, A. R., Lewis, A. G., Schoffelen, J.-M., & Schriefers, H. (2021). Semantic and syntactic composition of minimal adjective-noun phrases in Dutch: An MEG study. Neuropsychologia, 155: 107754. doi:10.1016/j.neuropsychologia.2021.107754.

    Abstract

    The possibility to combine smaller units of meaning (e.g., words) to create new and more complex meanings (e.g., phrases and sentences) is a fundamental feature of human language. In the present project, we investigated how the brain supports the semantic and syntactic composition of two-word adjective-noun phrases in Dutch, using magnetoencephalography (MEG). The present investigation followed up on previous studies reporting a composition effect in the left anterior temporal lobe (LATL) when comparing neural activity at nouns combined with adjectives, as opposed to nouns in a non-compositional context. The first aim of the present study was to investigate whether this effect, as well as its modulation by noun specificity and adjective class, can also be observed in Dutch. A second aim was to investigate to what extent these effects may be driven by syntactic composition rather than primarily by semantic composition as was previously proposed. To this end, a novel condition was administered in which participants saw nouns combined with pseudowords lacking meaning but agreeing with the nouns in terms of grammatical gender, as real adjectives would. We failed to observe a composition effect or its modulation in both a confirmatory analysis (focused on the cortical region and time-window where it has previously been reported) and in exploratory analyses (where we tested multiple regions and an extended potential time-window of the effect). A syntactically driven composition effect was also not observed in our data. We do, however, successfully observe an independent, previously reported effect on single word processing in our data, confirming that our MEG data processing pipeline does meaningfully capture language processing activity by the brain. The failure to observe the composition effect in LATL is surprising given that it has been previously reported in multiple studies. Reviewing all previous studies investigating this effect, we propose that materials and a task involving imagery might be necessary for this effect to be observed. In addition, we identified substantial variability in the regions of interest analyzed in previous studies, which warrants additional checks of robustness of the effect. Further research should identify limits and conditions under which this effect can be observed. The failure to observe specifically a syntactic composition effect in such minimal phrases is less surprising given that it has not been previously reported in MEG data.
  • Kong, X., Postema, M., Schijven, D., Carrion Castillo, A., Pepe, A., Crivello, F., Joliot, M., Mazoyer, B., Fisher, S. E., & Francks, C. (2021). Large-scale phenomic and genomic analysis of brain asymmetrical skew. Cerebral Cortex, 31(9), 4151-4168. doi:10.1093/cercor/bhab075.

    Abstract

    The human cerebral hemispheres show a left–right asymmetrical torque pattern, which has been claimed to be absent in chimpanzees. The functional significance and developmental mechanisms are unknown. Here, we carried out the largest-ever analysis of global brain shape asymmetry in magnetic resonance imaging data. Three population datasets were used, UK Biobank (N = 39 678), Human Connectome Project (N = 1113), and BIL&GIN (N = 453). At the population level, there was an anterior and dorsal skew of the right hemisphere, relative to the left. Both skews were associated independently with handedness, and various regional gray and white matter metrics oppositely in the two hemispheres, as well as other variables related to cognitive functions, sociodemographic factors, and physical and mental health. The two skews showed single nucleotide polymorphisms-based heritabilities of 4–13%, but also substantial polygenicity in causal mixture model analysis, and no individually significant loci were found in genome-wide association studies for either skew. There was evidence for a significant genetic correlation between horizontal brain skew and autism, which requires future replication. These results provide the first large-scale description of population-average brain skews and their inter-individual variations, their replicable associations with handedness, and insights into biological and other factors which associate with human brain asymmetry.
  • Konishi, M., Verdonschot, R. G., & Kakimoto, N. (2021). An investigation of tooth loss factors in elderly patients using panoramic radiographs. Oral Radiology, 37(3), 436-442. doi:10.1007/s11282-020-00475-6.

    Abstract

    Objectives The aim of this study was to observe the dental condition in a group of elderly patients over a period of 10 years in order to clarify important risk factors. Materials and methods Participants were elderly patients (in their eighties) who took panoramic radiographs between 2015 and 2016, and for whom panoramic radiographs taken around 10 year earlier were also available. The number of remaining and lost teeth, the Eichner Index, the presence or absence of molar occlusion, the respective condition of dental pulp, dental crowns, alveolar bone resorption, as well as periapical lesions were investigated through the analysis of panoramic radiographs. Additionally, other important variables were collected from patients' medical records. From the obtained panoramic radiograph sets, the patients' dental condition was investigated, and a systematic comparison was conducted. Results The analysis of the panoramic radiographs showed that the number of remaining teeth decreased from an average of 20.8-15.5, and the percentage of patients with 20 or more teeth decreased from 69.2 to 26.9%. A factor analysis investigating tooth loss risk suggested that tooth loss was associated with the bridge, P2 or greater resorption of the alveolar bone, and apical lesions, and gender (with males having a higher risk compared to females). Conclusions Teeth showing P2 or greater alveolar bone resorption, bridge, and apical lesions on panoramic radiographs are most likely to be lost in an elderly patient's near future. Consequently, this group should be encouraged to visit their dental clinics regularly and receive comprehensive instruction on individual self-care methods.
  • Konishi, M., Fujita, M., Shimabukuro, K., Wongratwanich, P., Verdonschot, R. G., & Kakimoto, N. (2021). Intraoral ultrasonographic features of tongue cancer and the incidence of cervical lymph node metastasis. Journal of Oral and Maxillofacial Surgery, 79(4), 932-939. doi:10.1016/j.joms.2020.09.006.

    Abstract

    Purpose: The purpose of this study was to investigate the relationship between the visual characteristics of tongue lesion images obtained through intraoral ultrasonographic examination and the occurrence of late cervical lymph node metastasis in patients with tongue cancer.
    Patients and Methods: This study investigated patients with primary tongue cancer who were examined using intraoral ultrasonography at Hiroshima University Hospital between January 2014 and December 2017. The inclusion criteria were squamous cell carcinoma, curative treatment administration, lateral side of tongue, surgery or brachytherapy alone, no cervical lymph node or distant metastasis as primary treatment, and treatment in our hospital. The exclusion criteria were carcinoma in situ, palliative treatment, dorsum of tongue, and multiple primary cancers. The follow-up period was more than 1 year. The primary endpoint was the occurrence of late cervical lymph node metastasis, and the primary predictor variables were age, gender, longest diameter, thickness, margin or border shapes of the lesion, and treatment methods. The relationship between the occurrence of late cervical lymph node metastasis and the longest diameter, thickness, margin types, and border types as evaluated through intraoral ultrasonography were assessed. The data were collected through a retrospective chart review.
    Results: Fifty-four patients were included in this study. The analysis indicated that irregular lesion margins were significantly associated with the occurrence of late cervical lymph node metastasis (P < .0001). The cutoff value for late cervical lymph node metastasis was 21.2 mm for the longest diameter and 3.9 mm for the thickness.
    Conclusions: The results of this study indicates that the irregular lesion margin assessed using intraoral ultrasonography may serve as an effective predictor of late cervical lymph node metastasis in N0 cases. (C) 2020 American Association of Oral and Maxillofacial Surgeons
  • Konishi, M., Fujita, M., Takeuchi, Y., Kubo, K., Imano, N., Nishibuchi, I., Murakami, Y., Shimabukuro, K., Wongratwanich, P., Verdonschot, R. G., Kakimoto, N., & Nagata, Y. (2021). Treatment outcomes of real-time intraoral sonography-guided implantation technique of 198Au grain brachytherapy for T1 and T2 tongue cancer. Journal of Radiation Research, 62(5), 871-876. doi:10.1093/jrr/rrab059.

    Abstract

    It is often challenging to determine the accurate size and shape of oral lesions through computed tomography (CT) or magnetic resonance imaging (MRI) when they are very small or obscured by metallic artifacts, such as dental prostheses. Intraoral ultrasonography (IUS) has been shown to be beneficial in obtaining precise information about total tumor extension, as well as the exact location and guiding the insertion of catheters during interstitial brachytherapy. We evaluated the role of IUS in assessing the clinical outcomes of interstitial brachytherapy with 198Au grains in tongue cancer through a retrospective medical chart review. The data from 45 patients with T1 (n = 21) and T2 (n = 24) tongue cancer, who were mainly treated with 198Au grain implants between January 2005 and April 2019, were included in this study. 198Au grain implantations were carried out, and positioning of the implants was confirmed by IUS, to ensure that 198Au grains were appropriately placed for the deep border of the tongue lesion. The five-year local control rates of T1 and T2 tongue cancers were 95.2% and 95.5%, respectively. We propose that the use of IUS to identify the extent of lesions and the position of implanted grains is effective when performing brachytherapy with 198Au grains.
  • Korvorst, M., Roelofs, A., & Levelt, W. J. M. (2007). Telling time from analog and digital clocks: A multiple-route account. Experimental Psychology, 54(3), 187-191. doi:10.1027/1618-3169.54.3.187.

    Abstract

    Does the naming of clocks always require conceptual preparation? To examine this question, speakers were presented with analog and digital clocks that had to be named in Dutch using either a relative (e.g., “quarter to four”) or an absolute (e.g., “three forty-five”) clock time expression format. Naming latencies showed evidence of conceptual preparation when speakers produced relative time expressions to analog and digital clocks, but not when they used absolute time expressions. These findings indicate that conceptual mediation is not always mandatory for telling time, but instead depends on clock time expression format, supporting a multiple-route account of Dutch clock time naming.
  • Kristiansen, M., Deriziotis, P., Dimcheff, D. E., Jackson, G. S., Ovaa, H., Naumann, H., Clarke, A. R., van Leeuwen, F. W., Menéndez-Benito, V., Dantuma, N. P., Portis, J. L., Collinge, J., & Tabrizi, S. J. (2007). Disease-associated prion protein oligomers inhibit the 26S proteasome. Molecular Cell, 26, 175-188. doi:10.1016/j.molcel.2007.04.001.

    Abstract

    * Kristiansen, M., Deriziotis, P. These authors contributed equally to this work.* - The mechanism of cell death in prion disease is unknown but is associated with the production of a misfolded conformer of the prion protein. We report that disease-associated prion protein specifically inhibits the proteolytic β subunits of the 26S proteasome. Using reporter substrates, fluorogenic peptides, and an activity probe for the β subunits, this inhibitory effect was demonstrated in pure 26S proteasome and three different cell lines. By challenge with recombinant prion and other amyloidogenic proteins, we demonstrate that only the prion protein in a nonnative β sheet conformation inhibits the 26S proteasome at stoichiometric concentrations. Preincubation with an antibody specific for aggregation intermediates abrogates this inhibition, consistent with an oligomeric species mediating this effect. We also present evidence for a direct relationship between prion neuropathology and impairment of the ubiquitin-proteasome system (UPS) in prion-infected UPS-reporter mice. Together, these data suggest a mechanism for intracellular neurotoxicity mediated by oligomers of misfolded prion protein.

    Additional information

    MolCellSup.pdf
  • Kuiper, K., Van Egmond, M.-E., Kempen, G., & Sprenger, S. A. (2007). Slipping on superlemmas: Multiword lexical items in speech production. The Mental Lexicon, 2(3), 313-357.

    Abstract

    Only relatively recently have theories of speech production concerned themselves with the part idioms and other multi-word lexical items (MLIs) play in the processes of speech production. Two theories of speech production which attempt to account for the accessing of idioms in speech production are those of Cutting and Bock (1997) and superlemma theory (Sprenger, 2003; Sprenger, Levelt, & Kempen, 2006). Much of the data supporting theories of speech production comes either from time course experiments or from slips of the tongue (Bock & Levelt, 1994). The latter are of two kinds: experimentally induced (Baars, 1992) or naturally observed (Fromkin, 1980). Cutting and Bock use experimentally induced speech errors while Sprenger et al. use time course experiments. The missing data type that has a bearing on speech production involving MLIs is that of naturally occurring slips. In this study the impact of data taken from naturally observed slips involving English and Dutch MLIs are brought to bear on these theories. The data are taken initially from a corpus of just over 1000 naturally observed English slips involving MLIs (the Tuggy corpus). Our argument proceeds as follows. First we show that slips occur independent of whether or not there are MLIs involved. In other words, speech production proceeds in certain of its aspects as though there were no MLI present. We illustrate these slips from the Tuggy data. Second we investigate the predictions of superlemma theory. Superlemma theory (Sprenger et al., 2006) accounts for the selection of MLIs and how their properties enter processes of speech production. It predicts certain activation patterns dependent on a MLI being selected. Each such pattern might give rise to slips of the tongue. This set of predictions is tested against the Tuggy data. Each of the predicted activation patterns yields a significant number of slips. These findings are therefore compatible with a view of MLIs as single units in so far as their activation by lexical concepts goes. However, the theory also predicts that some slips are likely not to occur. We confirm that such slips are not present in the data. These findings are further corroborated by reference a second smaller dataset of slips involving Dutch MLIs (the Kempen corpus). We then use slips involving irreversible binomials to distinguish between the predictions of superlemma theory which are supported by slips involving irreversible binomials and the Cutting and Bock model's predictions for slips involving these MLIs which are not
  • Kuperman, V., Pluymaekers, M., Ernestus, M., & Baayen, R. H. (2007). Morphological predictability and acoustic duration of interfixes in Dutch compounds. Journal of the Acoustical Society of America, 121(4), 2261-2271. doi:10.1121/1.2537393.

    Abstract

    This study explores the effects of informational redundancy, as carried by a word's morphological paradigmatic structure, on acoustic duration in read aloud speech. The hypothesis that the more predictable a linguistic unit is, the less salient its realization, was tested on the basis of the acoustic duration of interfixes in Dutch compounds in two datasets: One for the interfix -s- (1155 tokens) and one for the interfix -e(n)- (742 tokens). Both datasets show that the more probable the interfix is, given the compound and its constituents, the longer it is realized. These findings run counter to the predictions of information-theoretical approaches and can be resolved by the Paradigmatic Signal Enhancement Hypothesis. This hypothesis argues that whenever selection of an element from alternatives is probabilistic, the element's duration is predicted by the amount of paradigmatic support for the element: The most likely alternative in the paradigm of selection is realized longer.
  • Kuzla, C., Cho, T., & Ernestus, M. (2007). Prosodic strengthening of German fricatives in duration and assimilatory devoicing. Journal of Phonetics, 35(3), 301-320. doi:10.1016/j.wocn.2006.11.001.

    Abstract

    This study addressed prosodic effects on the duration of and amount of glottal vibration in German word-initial fricatives /f, v, z/ in assimilatory and non-assimilatory devoicing contexts. Fricatives following /small schwa/ (non-assimilation context) were longer and were produced with less glottal vibration after higher prosodic boundaries, reflecting domain-initial prosodic strengthening. After /t/ (assimilation context), lenis fricatives (/v, z/) were produced with less glottal vibration than after /small schwa/, due to assimilatory devoicing. This devoicing was especially strong across lower prosodic boundaries, showing the influence of prosodic structure on sandhi processes. Reduction in glottal vibration made lenis fricatives more fortis-like (/f, s/). Importantly, fricative duration, another major cue to the fortis-lenis distinction, was affected by initial lengthening, but not by assimilation. Hence, at smaller boundaries, fricatives were more devoiced (more fortis-like), but also shorter (more lenis-like). As a consequence, the fortis and lenis fricatives remained acoustically distinct in all prosodic and segmental contexts. Overall, /z/ was devoiced to a greater extent than /v/. Since /z/ does not have a fortis counterpart in word-initial position, these findings suggest that phonotactic restrictions constrain phonetic processes. The present study illuminates a complex interaction of prosody, sandhi processes, and phonotactics, yielding systematic phonetic cues to prosodic structure and phonological distinctions.
  • Lai, C. S. L., Fisher, S. E., Hurst, J. A., Vargha-Khadem, F., & Monaco, A. P. (2001). A forkhead-domain gene is mutated in a severe speech and language disorder[Letters to Nature]. Nature, 413, 519-523. doi:10.1038/35097076.

    Abstract

    Individuals affected with developmental disorders of speech and language have substantial difficulty acquiring expressive and/or receptive language in the absence of any profound sensory or neurological impairment and despite adequate intelligence and opportunity. Although studies of twins consistently indicate that a significant genetic component is involved, most families segregating speech and language deficits show complex patterns of inheritance, and a gene that predisposes individuals to such disorders has not been identified. We have studied a unique three-generation pedigree, KE, in which a severe speech and language disorder is transmitted as an autosomal-dominant monogenic trait. Our previous work mapped the locus responsible, SPCH1, to a 5.6-cM interval of region 7q31 on chromosome 7 (ref. 5). We also identified an unrelated individual, CS, in whom speech and language impairment is associated with a chromosomal translocation involving the SPCH1 interval. Here we show that the gene FOXP2, which encodes a putative transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain, is directly disrupted by the translocation breakpoint in CS. In addition, we identify a point mutation in affected members of the KE family that alters an invariant amino-acid residue in the forkhead domain. Our findings suggest that FOXP2 is involved in the developmental process that culminates in speech and language
  • Lai, C. S. L., Fisher, S. E., Hurst, J. A., Levy, E. R., Hodgson, S., Fox, M., Jeremiah, S., Povey, S., Jamison, D. C., Green, E. D., Vargha-Khadem, F., & Monaco, A. P. (2000). The SPCH1 region on human 7q31: Genomic characterization of the critical interval and localization of translocations associated with speech and language disorder. American Journal of Human Genetics, 67(2), 357-368. doi:10.1086/303011.

    Abstract

    The KE family is a large three-generation pedigree in which half the members are affected with a severe speech and language disorder that is transmitted as an autosomal dominant monogenic trait. In previously published work, we localized the gene responsible (SPCH1) to a 5.6-cM region of 7q31 between D7S2459 and D7S643. In the present study, we have employed bioinformatic analyses to assemble a detailed BAC-/PAC-based sequence map of this interval, containing 152 sequence tagged sites (STSs), 20 known genes, and >7.75 Mb of completed genomic sequence. We screened the affected chromosome 7 from the KE family with 120 of these STSs (average spacing <100 kb), but we did not detect any evidence of a microdeletion. Novel polymorphic markers were generated from the sequence and were used to further localize critical recombination breakpoints in the KE family. This allowed refinement of the SPCH1 interval to a region between new markers 013A and 330B, containing ∼6.1 Mb of completed sequence. In addition, we have studied two unrelated patients with a similar speech and language disorder, who have de novo translocations involving 7q31. Fluorescence in situ hybridization analyses with BACs/PACs from the sequence map localized the t(5;7)(q22;q31.2) breakpoint in the first patient (CS) to a single clone within the newly refined SPCH1 interval. This clone contains the CAGH44 gene, which encodes a brain-expressed protein containing a large polyglutamine stretch. However, we found that the t(2;7)(p23;q31.3) breakpoint in the second patient (BRD) resides within a BAC clone mapping >3.7 Mb distal to this, outside the current SPCH1 critical interval. Finally, we investigated the CAGH44 gene in affected individuals of the KE family, but we found no mutations in the currently known coding sequence. These studies represent further steps toward the isolation of the first gene to be implicated in the development of speech and language.
  • Lattenkamp, E. Z., Hörpel, S. G., Mengede, J., & Firzlaff, U. (2021). A researcher’s guide to the comparison of vocal production learning. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 376: 20200237. doi:10.1098/rstb.2020.0237.

    Abstract

    Vocal production learning (VPL) is the capacity to learn to produce new vocalizations, which is a rare ability in the animal kingdom and thus far has only been identified in a handful of mammalian taxa and three groups of birds. Over the last few decades, approaches to the demonstration of VPL have varied among taxa, sound production systems and functions. These discrepancies strongly impede direct comparisons between studies. In the light of the growing number of experimental studies reporting VPL, the need for comparability is becoming more and more pressing. The comparative evaluation of VPL across studies would be facilitated by unified and generalized reporting standards, which would allow a better positioning of species on any proposed VPL continuum. In this paper, we specifically highlight five factors influencing the comparability of VPL assessments: (i) comparison to an acoustic baseline, (ii) comprehensive reporting of acoustic parameters, (iii) extended reporting of training conditions and durations, (iv) investigating VPL function via behavioural, perception-based experiments and (v) validation of findings on a neuronal level. These guidelines emphasize the importance of comparability between studies in order to unify the field of vocal learning.
  • Lattenkamp, E. Z., Linnenschmidt, M., Mardus, E., Vernes, S. C., Wiegrebe, L., & Schutte, M. (2021). The vocal development of the pale spear-nosed bat is dependent on auditory feedback. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences, 376: 20200253. doi:10.1098/rstb.2020.0253.

    Abstract

    Human vocal development and speech learning require acoustic feedback, and
    humans who are born deaf do not acquire a normal adult speech capacity. Most
    other mammals display a largely innate vocal repertoire. Like humans, bats are
    thought to be one of the few taxa capable of vocal learning as they can acquire
    new vocalizations by modifying vocalizations according to auditory experiences.
    We investigated the effect of acoustic deafening on the vocal development of the
    pale spear-nosed bat. Three juvenile pale spear-nosed bats were deafened, and
    their vocal development was studied in comparison with an age-matched, hear-
    ing control group. The results show that during development the deafened bats
    increased their vocal activity, and their vocalizations were substantially altered,
    being much shorter, higher in pitch, and more aperiodic than the vocalizations
    of the control animals. The pale spear-nosed bat relies on auditory feedback
    for vocal development and, in the absence of auditory input, species-atypical
    vocalizations are acquired. This work serves as a basis for further research
    using the pale spear-nosed bat as a mammalian model for vocal learning, and
    contributes to comparative studies on hearing impairment across species.
    This article is part of the theme issue ‘Vocal learning in animals and
    humans’.
  • Lattenkamp, E. Z., Nagy, M., Drexl, M., Vernes, S. C., Wiegrebe, L., & Knörnschild, M. (2021). Hearing sensitivity and amplitude coding in bats are differentially shaped by echolocation calls and social calls. Proceedings of the Royal Society B: Biological Sciences, 288(1942): 20202600. doi:10.1098/rspb.2020.2600.

    Abstract

    Differences in auditory perception between species are influenced by phylogenetic origin and the perceptual challenges imposed by the natural environment, such as detecting prey- or predator-generated sounds and communication signals. Bats are well suited for comparative studies on auditory perception since they predominantly rely on echolocation to perceive the world, while their social calls and most environmental sounds have low frequencies. We tested if hearing sensitivity and stimulus level coding in bats differ between high and low-frequency ranges by measuring auditory brainstem responses (ABRs) of 86 bats belonging to 11 species. In most species, auditory sensitivity was equally good at both high- and low-frequency ranges, while amplitude was more finely coded for higher frequency ranges. Additionally, we conducted a phylogenetic comparative analysis by combining our ABR data with published data on 27 species. Species-specific peaks in hearing sensitivity correlated with peak frequencies of echolocation calls and pup isolation calls, suggesting that changes in hearing sensitivity evolved in response to frequency changes of echolocation and social calls. Overall, our study provides the most comprehensive comparative assessment of bat hearing capacities to date and highlights the evolutionary pressures acting on their sensory perception.

    Additional information

    data
  • Law, R., & Pylkkänen, L. (2021). Lists with and without syntax: A new approach to measuring the neural processing of syntax. The Journal of Neuroscience, 41(10), 2186-2196. doi:10.1523/JNEUROSCI.1179-20.2021.

    Abstract

    In the neurobiology of language, a fundamental challenge is deconfounding syntax from semantics. Changes in syntactic structure usually correlate with changes in meaning. We approached this challenge from a new angle. We deployed word lists, which are usually the unstructured control in studies of syntax, as both the test and the control stimulus. Three-noun lists (lamps, dolls, guitars) were embedded in sentences (The eccentric man hoarded lamps, dolls, guitars…) and in longer lists (forks, pen, toilet, rodeo, graves, drums, mulch, lamps, dolls, guitars…). This allowed us to perfectly control both lexical characteristics and local combinatorics: the same words occurred in both conditions and in neither case did the list items locally compose into phrases (e.g. ‘lamps’ and ‘dolls’ do not form a phrase). But in one case, the list partakes in a syntactic tree, while in the other, it does not. Being embedded inside a syntactic tree increased source-localized MEG activity at ~250-300ms from word onset in the left inferior frontal cortex, at ~300-350ms in the left anterior temporal lobe and, most reliably, at ~330-400ms in left posterior temporal cortex. In contrast, effects of semantic association strength, which we also varied, localized in left temporo-parietal cortex, with high associations increasing activity at around 400ms. This dissociation offers a novel characterization of the structure vs. meaning contrast in the brain: The fronto-temporal network that is familiar from studies of sentence processing can be driven by the sheer presence of global sentence structure, while associative semantics has a more posterior neural signature.

    Additional information

    Link to Preprint on BioRxiv
  • Ledberg, A., Fransson, P., Larsson, J., & Petersson, K. M. (2001). A 4D approach to the analysis of functional brain images: Application to fMRI data. Human Brain Mapping, 13, 185-198. doi:10.1002/hbm.1032.

    Abstract

    This paper presents a new approach to functional magnetic resonance imaging (FMRI) data analysis. The main difference lies in the view of what comprises an observation. Here we treat the data from one scanning session (comprising t volumes, say) as one observation. This is contrary to the conventional way of looking at the data where each session is treated as t different observations. Thus instead of viewing the v voxels comprising the 3D volume of the brain as the variables, we suggest the usage of the vt hypervoxels comprising the 4D volume of the brain-over-session as the variables. A linear model is fitted to the 4D volumes originating from different sessions. Parameter estimation and hypothesis testing in this model can be performed with standard techniques. The hypothesis testing generates 4D statistical images (SIs) to which any relevant test statistic can be applied. In this paper we describe two test statistics, one voxel based and one cluster based, that can be used to test a range of hypotheses. There are several benefits in treating the data from each session as one observation, two of which are: (i) the temporal characteristics of the signal can be investigated without an explicit model for the blood oxygenation level dependent (BOLD) contrast response function, and (ii) the observations (sessions) can be assumed to be independent and hence inference on the 4D SI can be made by nonparametric or Monte Carlo methods. The suggested 4D approach is applied to FMRI data and is shown to accurately detect the expected signal
  • Lehtonen, M., Cunillera, T., Rodríguez-Fornells, A., Hultén, A., Tuomainen, J., & Laine, M. (2007). Recognition of morphologically complex words in Finnish: Evidence from event-related potentials. Brain Research, 1148, 123-137. doi:10.1016/j.brainres.2007.02.026.

    Abstract

    The temporal dynamics of processing morphologically complex words was investigated by recording event-related brain potentials (ERPs) when native Finnish-speakers performed a visual lexical decision task. Behaviorally, there is evidence that recognition of inflected nouns elicits a processing cost (i.e., longer reaction times and higher error rates) in comparison to matched monomorphemic words. We aimed to reveal whether the processing cost stems from decomposition at the early visual word form level or from recomposition at the later semantic–syntactic level. The ERPs showed no early effects for morphology, but revealed an interaction with word frequency at a late N400-type component, as well as a late positive component that was larger for inflected words. These results suggest that the processing cost stems mainly from the semantic–syntactic level. We also studied the features of the morphological decomposition route by investigating the recognition of pseudowords carrying real morphemes. The results showed no differences between inflected vs. uninflected pseudowords with a false stem, but differences in relation to those with a real stem, suggesting that a recognizable stem is needed to initiate the decomposition route.
  • Lemen, H., Lieven, E., & Theakston, A. (2021). A comparison of the pragmatic patterns in the spontaneous because- and if-sentences produced by children and their caregivers. Journal of Pragmatics, 185, 15-34. doi:10.1016/j.pragma.2021.07.016.

    Abstract

    Findings from corpus (e.g. Diessel, 2004) and comprehension (e.g. De Ruiter et al., 2018) studies show that children produce the adverbial connectives because and if long before they seem able to understand them. However, although children's comprehension is typically tested on sentences expressing the pragmatic relationship which Sweetser (1990) calls “Content”, children also hear and produce sentences expressing “Speech–Act” relationships (e.g. De Ruiter et al., 2021; Kyratzis et al., 1990). To better understand the possible influence of pragmatic variation on 2- to 4- year-old children's acquisition of these connectives, we coded the because and if Speech–Act sentences of 14 British English-speaking mother-child dyads for the type of illocutionary act they contained, as well as the phrasing following the connective. Analyses revealed that children's because Speech–Act sentences were primarily explanations of Statements/Claims, while their if Speech–Act sentences typically related to permission and politeness. While children's because-sentences showed a great deal of individuality, their if-sentences closely resembled their mothers’, containing a high proportion of recurring phrases which appear to be abstracted from input. We discuss how these patterns might help shape children's understanding of each connective and contribute to the children's overall difficulty with because and if.
  • Levelt, W. J. M. (2000). Uit talloos veel miljoenen. Natuur & Techniek, 68(11), 90.
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (1999). A developmental grammar for syllable structure in the production of child language. Brain and Language, 68, 291-299.

    Abstract

    The order of acquisition of Dutch syllable types by first language learners is analyzed as following from an initial ranking and subsequent rerankings of constraints in an optimality theoretic grammar. Initially, structural constraints are all ranked above faithfulness constraints, leading to core syllable (CV) productions only. Subsequently, faithfulness gradually rises to the highest position in the ranking, allowing more and more marked syllable types to appear in production. Local conjunctions of Structural constraints allow for a more detailed analysis.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). A theory of lexical access in speech production. Behavioral and Brain Sciences, 22, 1-38. doi:10.1017/S0140525X99001776.

    Abstract

    Preparing words in speech production is normally a fast and accurate process. We generate them two or three per second in fluent conversation; and overtly naming a clear picture of an object can easily be initiated within 600 msec after picture onset. The underlying process, however, is exceedingly complex. The theory reviewed in this target article analyzes this process as staged and feedforward. After a first stage of conceptual preparation, word generation proceeds through lexical selection, morphological and phonological encoding, phonetic encoding, and articulation itself. In addition, the speaker exerts some degree of output control, by monitoring of self-produced internal and overt speech. The core of the theory, ranging from lexical selection to the initiation of phonetic encoding, is captured in a computational model, called WEAVER + +. Both the theory and the computational model have been developed in interaction with reaction time experiments, particularly in picture naming or related word production paradigms, with the aim of accounting. for the real-time processing in normal word production. A comprehensive review of theory, model, and experiments is presented. The model can handle some of the main observations in the domain of speech errors (the major empirical domain for most other theories of lexical access), and the theory opens new ways of approaching the cerebral organization of speech production by way of high-temporal-resolution imaging.
  • Levelt, W. J. M. (2001). De vlieger die (onverwacht) wel opgaat. Natuur & Techniek, 69(6), 60.
  • Levelt, W. J. M. (2001). Defining dyslexia. Science, 292, 1300-1301.
  • Levelt, W. J. M. (2000). Dyslexie. Natuur & Techniek, 68(4), 64.
  • Levelt, W. J. M. (1999). Models of word production. Trends in Cognitive Sciences, 3, 223-232.

    Abstract

    Research on spoken word production has been approached from two angles. In one research tradition, the analysis of spontaneous or induced speech errors led to models that can account for speech error distributions. In another tradition, the measurement of picture naming latencies led to chronometric models accounting for distributions of reaction times in word production. Both kinds of models are, however, dealing with the same underlying processes: (1) the speaker’s selection of a word that is semantically and syntactically appropriate; (2) the retrieval of the word’s phonological properties; (3) the rapid syllabification of the word in context; and (4) the preparation of the corresponding articulatory gestures. Models of both traditions explain these processes in terms of activation spreading through a localist, symbolic network. By and large, they share the main levels of representation: conceptual/semantic, syntactic, phonological and phonetic. They differ in various details, such as the amount of cascading and feedback in the network. These research traditions have begun to merge in recent years, leading to highly constructive experimentation. Currently, they are like two similar knives honing each other. A single pair of scissors is in the making.
  • Levelt, W. J. M., Roelofs, A., & Meyer, A. S. (1999). Multiple perspectives on lexical access [authors' response ]. Behavioral and Brain Sciences, 22, 61-72. doi:10.1017/S0140525X99451775.
  • Levelt, W. J. M. (1997). Kunnen lezen is ongewoon voor horenden en doven. Tijdschrift voor Jeugdgezondheidszorg, 29(2), 22-25.
  • Levelt, W. J. M. (1982). Het lineariseringsprobleem van de spreker. Tijdschrift voor Taal- en Tekstwetenschap (TTT), 2(1), 1-15.
  • Levelt, W. J. M. (2000). Links en rechts: Waarom hebben we zo vaak problemen met die woorden? Natuur & Techniek, 68(7/8), 90.
  • Levelt, W. J. M. (1967). Note on the distribution of dominance times in binocular rivalry. British Journal of Psychology, 58, 143-145.
  • Levelt, C. C., Schiller, N. O., & Levelt, W. J. M. (2000). The acquisition of syllable types. Language Acquisition, 8(3), 237-263. doi:10.1207/S15327817LA0803_2.

    Abstract

    In this article, we present an account of developmental data regarding the acquisition of syllable types. The data come from a longitudinal corpus of phonetically transcribed speech of 12 children acquiring Dutch as their first language. A developmental order of acquisition of syllable types was deduced by aligning the syllabified data on a Guttman scale. This order could be analyzed as following from an initial ranking and subsequent rerankings in the grammar of the structural constraints ONSET, NO-CODA, *COMPLEX-O, and *COMPLEX-C; some local conjunctions of these constraints; and a faithfulness constraint FAITH. The syllable type frequencies in the speech surrounding the language learner are also considered. An interesting correlation is found between the frequencies and the order of development of the different syllable types.
  • Levelt, W. J. M. (2000). The brain does not serve linguistic theory so easily [Commentary to target article by Grodzinksy]. Behavioral and Brain Sciences, 23(1), 40-41.
  • Levelt, W. J. M. (2001). Spoken word production: A theory of lexical access. Proceedings of the National Academy of Sciences, 98, 13464-13471. doi:10.1073/pnas.231459498.

    Abstract

    A core operation in speech production is the preparation of words from a semantic base. The theory of lexical access reviewed in this article covers a sequence of processing stages beginning with the speaker’s focusing on a target concept and ending with the initiation of articulation. The initial stages of preparation are concerned with lexical selection, which is zooming in on the appropriate lexical item in the mental lexicon. The following stages concern form encoding, i.e., retrieving a word’s morphemic phonological codes, syllabifying the word, and accessing the corresponding articulatory gestures. The theory is based on chronometric measurements of spoken word production, obtained, for instance, in picture-naming tasks. The theory is largely computationally implemented. It provides a handle on the analysis of multiword utterance production as well as a guide to the analysis and design of neuroimaging studies of spoken utterance production.
  • Levelt, W. J. M., & Kelter, S. (1982). Surface form and memory in question answering. Cognitive Psychology, 14, 78-106. doi:10.1016/0010-0285(82)90005-6.

    Abstract

    Speakers tend to repeat materials from previous talk. This tendency is experimentally established and manipulated in various question-answering situations. It is shown that a question's surface form can affect the format of the answer given, even if this form has little semantic or conversational consequence, as in the pair Q: (At) what time do you close. A: “(At)five o'clock.” Answerers tend to match the utterance to the prepositional (nonprepositional) form of the question. This “correspondence effect” may diminish or disappear when, following the question, additional verbal material is presented to the answerer. The experiments show that neither the articulatory buffer nor long-term memory is normally involved in this retention of recent speech. Retaining recent speech in working memory may fulfill a variety of functions for speaker and listener, among them the correct production and interpretation of surface anaphora. Reusing recent materials may, moreover, be more economical than regenerating speech anew from a semantic base, and thus contribute to fluency. But the realization of this strategy requires a production system in which linguistic formulation can take place relatively independent of, and parallel to, conceptual planning.
  • Levelt, W. J. M. (1982). Science policy: Three recent idols, and a goddess. IPO Annual Progress Report, 17, 32-35.
  • Levelt, W. J. M. (2001). Woorden ophalen. Natuur en Techniek, 69(10), 74.
  • Levelt, W. J. M., & Meyer, A. S. (2000). Word for word: Multiple lexical access in speech production. European Journal of Cognitive Psychology, 12(4), 433-452. doi:10.1080/095414400750050178.

    Abstract

    It is quite normal for us to produce one or two million word tokens every year. Speaking is a dear occupation and producing words is at the core of it. Still, producing even a single word is a highly complex affair. Recently, Levelt, Roelofs, and Meyer (1999) reviewed their theory of lexical access in speech production, which dissects the word-producing mechanism as a staged application of various dedicated operations. The present paper begins by presenting a bird eye's view of this mechanism. We then square the complexity by asking how speakers control multiple access in generating simple utterances such as a table and a chair. In particular, we address two issues. The first one concerns dependency: Do temporally contiguous access procedures interact in any way, or do they run in modular fashion? The second issue concerns temporal alignment: How much temporal overlap of processing does the system tolerate in accessing multiple content words, such as table and chair? Results from picture-word interference and eye tracking experiments provide evidence for restricted cases of dependency as well as for constraints on the temporal alignment of access procedures.
  • Levelt, W. J. M. (1982). Zelfcorrecties in het spreekproces. KNAW: Mededelingen van de afdeling letterkunde, nieuwe reeks, 45(8), 215-228.
  • Levinson, S. C. (2007). Cut and break verbs in Yélî Dnye, the Papuan language of Rossel Island. Cognitive Linguistics, 18(2), 207-218. doi:10.1515/COG.2007.009.

    Abstract

    The paper explores verbs of cutting and breaking (C&B, hereafter) in Yeli Dnye, the Papuan language of Rossel Island. The Yeli Dnye verbs covering the C&B domain do not divide it in the expected way, with verbs focusing on special instruments and manners of action on the one hand, and verbs focusing on the resultant state on the other. Instead, just three transitive verbs and their intransitive counterparts cover most of the domain, and they are all based on 'exotic' distinctions in mode of severance[--]coherent severance with the grain vs. against the grain, and incoherent severance (regardless of grain).
  • Levinson, S. C. (1999). Maxim. Journal of Linguistic Anthropology, 9, 144-147. doi:10.1525/jlin.1999.9.1-2.144.
  • Levinson, S. C. (1997). Language and cognition: The cognitive consequences of spatial description in Guugu Yimithirr. Journal of Linguistic Anthropology, 7(1), 98-131. doi:10.1525/jlin.1997.7.1.98.

    Abstract

    This article explores the relation between language and cognition by examining the case of "absolute" (cardinal direction) spatial description in the Australian aboriginal language Guugu Yimithirr. This kind of spatial description is incongruent with the "relative" (e.g., left/right/front/back) spatial description familiar in European languages. Building on Haviland's 1993 analysis of Guugu Yimithirr directionals in speech and gesture, a series of informal experiments were developed. It is shown that Guugu Yimithirr speakers predominantly code for nonverbal memory in "absolute" concepts congruent with their language, while a comparative sample of Dutch speakers do so in "relative" concepts. Much anecdotal evidence also supports this. The conclusion is that Whorfian effects may in fact be demonstrable in the spatial domain.
  • Levinson, S. C. (1997). Language and cognition: The cognitive consequences of spatial description in Guugu Yimithirr. Journal of Linguistic Anthropology, 7(1), 1-35. doi:10.1525/jlin.1997.7.1.98.
  • Levinson, S. C. (2000). Yélî Dnye and the theory of basic color terms. Journal of Linguistic Anthropology, 10( 1), 3-55. doi:10.1525/jlin.2000.10.1.3.

    Abstract

    The theory of basic color terms was a crucial factor in the demise of linguistic relativity. The theory is now once again under scrutiny and fundamental revision. This article details a case study that undermines one of the central claims of the classical theory, namely that languages universally treat color as a unitary domain, to be exhaustively named. Taken together with other cases, the study suggests that a number of languages have only an incipient color terminology, raising doubts about the linguistic universality of such terminology.
  • Levshina, N. (2021). Cross-linguistic trade-offs and causal relationships between cues to grammatical subject and object, and the problem of efficiency-related explanations. Frontiers in Psychology, 12: 648200. doi:10.3389/fpsyg.2021.648200.

    Abstract

    Cross-linguistic studies focus on inverse correlations (trade-offs) between linguistic variables that reflect different cues to linguistic meanings. For example, if a language has no case marking, it is likely to rely on word order as a cue for identification of grammatical roles. Such inverse correlations are interpreted as manifestations of language users’ tendency to use language efficiently. The present study argues that this interpretation is problematic. Linguistic variables, such as the presence of case, or flexibility of word order, are aggregate properties, which do not represent the use of linguistic cues in context directly. Still, such variables can be useful for circumscribing the potential role of communicative efficiency in language evolution, if we move from cross-linguistic trade-offs to multivariate causal networks. This idea is illustrated by a case study of linguistic variables related to four types of Subject and Object cues: case marking, rigid word order of Subject and Object, tight semantics and verb-medial order. The variables are obtained from online language corpora in thirty languages, annotated with the Universal Dependencies. The causal model suggests that the relationships between the variables can be explained predominantly by sociolinguistic factors, leaving little space for a potential impact of efficient linguistic behavior.
  • Levshina, N., & Moran, S. (2021). Efficiency in human languages: Corpus evidence for universal principles. Linguistics Vanguard, 7(s3): 20200081. doi:10.1515/lingvan-2020-0081.

    Abstract

    Over the last few years, there has been a growing interest in communicative efficiency. It has been argued that language users act efficiently, saving effort for processing and articulation, and that language structure and use reflect this tendency. The emergence of new corpus data has brought to life numerous studies on efficient language use in the lexicon, in morphosyntax, and in discourse and phonology in different languages. In this introductory paper, we discuss communicative efficiency in human languages, focusing on evidence of efficient language use found in multilingual corpora. The evidence suggests that efficiency is a universal feature of human language. We provide an overview of different manifestations of efficiency on different levels of language structure, and we discuss the major questions and findings so far, some of which are addressed for the first time in the contributions in this special collection.
  • Levshina, N., & Moran, S. (Eds.). (2021). Efficiency in human languages: Corpus evidence for universal principles [Special Issue]. Linguistics Vanguard, 7(s3).
  • Levshina, N. (2021). Communicative efficiency and differential case marking: A reverse-engineering approach. Linguistics Vanguard, 7(s3): 20190087. doi:10.1515/lingvan-2019-0087.
  • Lieber, R., & Baayen, R. H. (1997). A semantic principle of auxiliary selection in Dutch. Natural Language & Linguistic Theory, 15(4), 789-845.

    Abstract

    We propose that the choice between the auxiliaries hebben 'have' and zijn 'be' in Dutch is determined by a particular semantic feature of verbs. In particular we propose a feature of meaning [IEPS] for 'inferable eventual position or state' that characterizes whether the action denoted by the verb allows us to determine the eventual position or state of the verb's highest argument. It is argued that only verbs which exhibit the feature [+IEPS] or which obtain the feature compositionally in the syntax select zijn as their auxiliary. Our analysis is then compared to a number of other analyses of auxiliary selection in Dutch.

    Additional information

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  • Liszkowski, U., Carpenter, M., & Tomasello, M. (2007). Reference and attitude in infant pointing. Journal of Child Language, 34(1), 1-20. doi:10.1017/S0305000906007689.

    Abstract

    We investigated two main components of infant declarative pointing, reference and attitude, in two experiments with a total of 106 preverbal infants at 1;0. When an experimenter (E) responded to the declarative pointing of these infants by attending to an incorrect referent (with positive attitude), infants repeated pointing within trials to redirect E’s attention, showing an understanding of E’s reference and active message repair. In contrast, when E identified infants’ referent correctly but displayed a disinterested attitude, infants did not repeat pointing within trials and pointed overall in fewer trials, showing an understanding of E’s unenthusiastic attitude about the referent. When E attended to infants’ intended referent AND shared interest in it, infants were most satisfied, showing no message repair within trials and pointing overall in more trials. These results suggest that by twelve months of age infant declarative pointing is a full communicative act aimed at sharing with others both attention to a referent and a specific attitude about that referent.
  • Liszkowski, U., Carpenter, M., & Tomasello, M. (2007). Pointing out new news, old news, and absent referents at 12 months of age. Developmental Science, 10(2), F1-F7. doi:0.1111/j.1467-7687.2006.00552.x.

    Abstract

    There is currently controversy over the nature of 1-year-olds' social-cognitive understanding and motives. In this study we investigated whether 12-month-old infants point for others with an understanding of their knowledge states and with a prosocial motive for sharing experiences with them. Declarative pointing was elicited in four conditions created by crossing two factors: an adult partner (1) was already attending to the target event or not, and (2) emoted positively or neutrally. Pointing was also coded after the event had ceased. The findings suggest that 12-month-olds point to inform others of events they do not know about, that they point to share an attitude about mutually attended events others already know about, and that they can point (already prelinguistically) to absent referents. These findings provide strong support for a mentalistic and prosocial interpretation of infants' prelinguistic communication
  • Lloyd, S. E., Günther, W., Pearce, S. H. S., Thomson, A., Bianchi, M. L., Bosio, M., Craig, I. W., Fisher, S. E., Scheinman, S. J., Wrong, O., Jentsch, T. J., & Thakker, R. V. (1997). Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders. Human Molecular Genetics, 6(8), 1233-1239. doi:10.1093/hmg/6.8.1233.

    Abstract

    Mutations of the renal-specific chloride channel (CLCN5) gene, which is located on chromosome Xp11.22, are associated with hypercalciuric nephrolithiasis (kidney stones) in the Northern European and Japanese populations. CLCN5 encodes a 746 amino acid channel (CLC-5) that has approximately 12 transmembrane domains, and heterologous expression of wild-type CLC-5 in Xenopus oocytes has yielded outwardly rectifying chloride currents that were markedly reduced or abolished by these mutations. In order to assess further the structural and functional relationships of this recently cloned chloride channel, additional CLCN5 mutations have been identified in five unrelated families with this disorder. Three of these mutations were missense (G57V, G512R and E527D), one was a nonsense (R648Stop) and one was an insertion (30:H insertion). In addition, two of the mutations (30:H insertion and E527D) were demonstrated to be de novo, and the G57V and E527D mutations were identified in families of Afro-American and Indian origin, respectively. The G57V and 30:H insertion mutations represent the first CLCN5 mutations to be identified in the N-terminus region, and the R648Stop mutation, which has been observed previously in an unrelated family, suggests that this codon may be particularly prone to mutations. Heterologous expression of the mutations resulted in a marked reduction or abolition of the chloride currents, thereby establishing their functional importance. These results help to elucidate further the structure-function relationships of this renal chloride channel.
  • Long, M., Moore, I., Mollica, F., & Rubio-Fernandez, P. (2021). Contrast perception as a visual heuristic in the formulation of referential expressions. Cognition, 217: 104879. doi:10.1016/j.cognition.2021.104879.

    Abstract

    We hypothesize that contrast perception works as a visual heuristic, such that when speakers perceive a significant degree of contrast in a visual context, they tend to produce the corresponding adjective to describe a referent. The contrast perception heuristic supports efficient audience design, allowing speakers to produce referential expressions with minimum expenditure of cognitive resources, while facilitating the listener's visual search for the referent. We tested the perceptual contrast hypothesis in three language-production experiments. Experiment 1 revealed that speakers overspecify color adjectives in polychrome displays, whereas in monochrome displays they overspecified other properties that were contrastive. Further support for the contrast perception hypothesis comes from a re-analysis of previous work, which confirmed that color contrast elicits color overspecification when detected in a given display, but not when detected across monochrome trials. Experiment 2 revealed that even atypical colors (which are often overspecified) are only mentioned if there is color contrast. In Experiment 3, participants named a target color faster in monochrome than in polychrome displays, suggesting that the effect of color contrast is not analogous to ease of production. We conclude that the tendency to overspecify color in polychrome displays is not a bottom-up effect driven by the visual salience of color as a property, but possibly a learned communicative strategy. We discuss the implications of our account for pragmatic theories of referential communication and models of audience design, challenging the view that overspecification is a form of egocentric behavior.

    Additional information

    supplementary data
  • Long, M., Shukla, V., & Rubio-Fernandez, P. (2021). The development of simile comprehension: From similarity to scalar implicature. Child Development, 92(4), 1439-1457. doi:10.1111/cdev.13507.

    Abstract

    Similes require two different pragmatic skills: appreciating the intended similarity and deriving a scalar implicature (e.g., “Lucy is like a parrot” normally implies that Lucy is not a parrot), but previous studies overlooked this second skill. In Experiment 1, preschoolers (N = 48; ages 3–5) understood “X is like a Y” as an expression of similarity. In Experiment 2 (N = 99; ages 3–6, 13) and Experiment 3 (N = 201; ages 3–5 and adults), participants received metaphors (“Lucy is a parrot”) or similes (“Lucy is like a parrot”) as clues to select one of three images (a parrot, a girl or a parrot-looking girl). An early developmental trend revealed that 3-year-olds started deriving the implicature “X is not a Y,” whereas 5-year-olds performed like adults.
  • Lopopolo, A., Van de Bosch, A., Petersson, K. M., & Willems, R. M. (2021). Distinguishing syntactic operations in the brain: Dependency and phrase-structure parsing. Neurobiology of Language, 2(1), 152-175. doi:10.1162/nol_a_00029.

    Abstract

    Finding the structure of a sentence — the way its words hold together to convey meaning — is a fundamental step in language comprehension. Several brain regions, including the left inferior frontal gyrus, the left posterior superior temporal gyrus, and the left anterior temporal pole, are supposed to support this operation. The exact role of these areas is nonetheless still debated. In this paper we investigate the hypothesis that different brain regions could be sensitive to different kinds of syntactic computations. We compare the fit of phrase-structure and dependency structure descriptors to activity in brain areas using fMRI. Our results show a division between areas with regard to the type of structure computed, with the left ATP and left IFG favouring dependency structures and left pSTG favouring phrase structures.
  • Lowndes, R., Molz, B., Warriner, L., Herbik, A., De Best, P. B., Raz, N., Gouws, A., Ahmadi, K., McLean, R. J., Gottlob, I., Kohl, S., Choritz, L., Maguire, J., Kanowski, M., Käsmann-Kellner, B., Wieland, I., Banin, E., Levin, N., Hoffmann, M. B., Morland, A. B. and 1 moreLowndes, R., Molz, B., Warriner, L., Herbik, A., De Best, P. B., Raz, N., Gouws, A., Ahmadi, K., McLean, R. J., Gottlob, I., Kohl, S., Choritz, L., Maguire, J., Kanowski, M., Käsmann-Kellner, B., Wieland, I., Banin, E., Levin, N., Hoffmann, M. B., Morland, A. B., & Baseler, H. A. (2021). Structural differences across multiple visual cortical regions in the absence of cone function in congenital achromatopsia. Frontiers in Neuroscience, 15: 718958. doi:10.3389/fnins.2021.718958.

    Abstract

    Most individuals with congenital achromatopsia (ACHM) carry mutations that affect the retinal phototransduction pathway of cone photoreceptors, fundamental to both high acuity vision and colour perception. As the central fovea is occupied solely by cones, achromats have an absence of retinal input to the visual cortex and a small central area of blindness. Additionally, those with complete ACHM have no colour perception, and colour processing regions of the ventral cortex also lack typical chromatic signals from the cones. This study examined the cortical morphology (grey matter volume, cortical thickness, and cortical surface area) of multiple visual cortical regions in ACHM (n = 15) compared to normally sighted controls (n = 42) to determine the cortical changes that are associated with the retinal characteristics of ACHM. Surface-based morphometry was applied to T1-weighted MRI in atlas-defined early, ventral and dorsal visual regions of interest. Reduced grey matter volume in V1, V2, V3, and V4 was found in ACHM compared to controls, driven by a reduction in cortical surface area as there was no significant reduction in cortical thickness. Cortical surface area (but not thickness) was reduced in a wide range of areas (V1, V2, V3, TO1, V4, and LO1). Reduction in early visual areas with large foveal representations (V1, V2, and V3) suggests that the lack of foveal input to the visual cortex was a major driving factor in morphological changes in ACHM. However, the significant reduction in ventral area V4 coupled with the lack of difference in dorsal areas V3a and V3b suggest that deprivation of chromatic signals to visual cortex in ACHM may also contribute to changes in cortical morphology. This research shows that the congenital lack of cone input to the visual cortex can lead to widespread structural changes across multiple visual areas.

    Additional information

    table S1
  • Lutzenberger, H., De Vos, C., Crasborn, O., & Fikkert, P. (2021). Formal variation in the Kata Kolok lexicon. Glossa: a journal of general linguistics, 6. doi:10.16995/glossa.5880.

    Abstract

    Sign language lexicons incorporate phonological specifications. Evidence from emerging sign languages suggests that phonological structure emerges gradually in a new language. In this study, we investigate variation in the form of signs across 20 deaf adult signers of Kata Kolok, a sign language that emerged spontaneously in a Balinese village community. Combining methods previously used for sign comparisons, we introduce a new numeric measure of variation. Our nuanced yet comprehensive approach to form variation integrates three levels (iconic motivation, surface realisation, feature differences) and allows for refinement through weighting the variation score by token and signer frequency. We demonstrate that variation in the form of signs appears in different degrees at different levels. Token frequency in a given dataset greatly affects how much variation can surface, suggesting caution in interpreting previous findings. Different sign variants have different scopes of use among the signing population, with some more widely used than others. Both frequency weightings (token and signer) identify dominant sign variants, i.e., sign forms that are produced frequently or by many signers. We argue that variation does not equal the absence of conventionalisation. Indeed, especially in micro-community sign languages, variation may be key to understanding patterns of language emergence.
  • Majid, A., Bowerman, M., Van Staden, M., & Boster, J. S. (2007). The semantic categories of cutting and breaking events: A crosslinguistic perspective. Cognitive Linguistics, 18(2), 133-152. doi:10.1515/COG.2007.005.

    Abstract

    This special issue of Cognitive Linguistics explores the linguistic encoding of events of cutting and breaking. In this article we first introduce the project on which it is based by motivating the selection of this conceptual domain, presenting the methods of data collection used by all the investigators, and characterizing the language sample. We then present a new approach to examining crosslinguistic similarities and differences in semantic categorization. Applying statistical modeling to the descriptions of cutting and breaking events elicited from speakers of all the languages, we show that although there is crosslinguistic variation in the number of distinctions made and in the placement of category boundaries, these differences take place within a strongly constrained semantic space: across languages, there is a surprising degree of consensus on the partitioning of events in this domain. In closing, we compare our statistical approach with more conventional semantic analyses, and show how...
  • Majid, A., Sanford, A. J., & Pickering, M. J. (2007). The linguistic description of minimal social scenarios affects the extent of causal inference making. Journal of Experimental Social Psychology, 43(6), 918-932. doi:10.1016/j.jesp.2006.10.016.

    Abstract

    There is little consensus regarding the circumstances in which people spontaneously generate causal inferences, and in particular whether they generate inferences about the causal antecedents or the causal consequences of events. We tested whether people systematically infer causal antecedents or causal consequences to minimal social scenarios by using a continuation methodology. People overwhelmingly produced causal antecedent continuations for descriptions of interpersonal events (John hugged Mary), but causal consequence continuations to descriptions of transfer events (John gave a book to Mary). This demonstrates that there is no global cognitive style, but rather inference generation is crucially tied to the input. Further studies examined the role of event unusualness, number of participators, and verb-type on the likelihood of producing a causal antecedent or causal consequence inference. We conclude that inferences are critically guided by the specific verb used.
  • Majid, A., & Bowerman, M. (Eds.). (2007). Cutting and breaking events: A crosslinguistic perspective [Special Issue]. Cognitive Linguistics, 18(2).

    Abstract

    This special issue of Cognitive Linguistics explores the linguistic encoding of events of cutting and breaking. In this article we first introduce the project on which it is based by motivating the selection of this conceptual domain, presenting the methods of data collection used by all the investigators, and characterizing the language sample. We then present a new approach to examining crosslinguistic similarities and differences in semantic categorization. Applying statistical modeling to the descriptions of cutting and breaking events elicited from speakers of all the languages, we show that although there is crosslinguistic variation in the number of distinctions made and in the placement of category boundaries, these differences take place within a strongly constrained semantic space: across languages, there is a surprising degree of consensus on the partitioning of events in this domain. In closing, we compare our statistical approach with more conventional semantic analyses, and show how an extensional semantic typological approach like the one illustrated here can help illuminate the intensional distinctions made by languages.
  • Majid, A., Gullberg, M., Van Staden, M., & Bowerman, M. (2007). How similar are semantic categories in closely related languages? A comparison of cutting and breaking in four Germanic languages. Cognitive Linguistics, 18(2), 179-194. doi:10.1515/COG.2007.007.

    Abstract

    Are the semantic categories of very closely related languages the same? We present a new methodology for addressing this question. Speakers of English, German, Dutch and Swedish described a set of video clips depicting cutting and breaking events. The verbs elicited were then subjected to cluster analysis, which groups scenes together based on similarity (determined by shared verbs). Using this technique, we find that there are surprising differences among the languages in the number of categories, their exact boundaries, and the relationship of the terms to one another[--]all of which is circumscribed by a common semantic space.
  • Mak, M., & Willems, R. M. (2021). Eyelit: Eye movement and reader response data during literary reading. Journal of open humanities data, 7: 25. doi:10.5334/johd.49.

    Abstract

    An eye-tracking data set is described of 102 participants reading three Dutch literary short stories each (7790 words in total per participant). The pre-processed data set includes (1) Fixation report, (2) Saccade report, (3) Interest Area report, (4) Trial report (aggregated data for each page), (5) Sample report (sampling rate = 500 Hz), (6) Questionnaire data on reading experiences and participant characteristics, and (7) word characteristics for all words (with the potential of calculating additional word characteristics). It is stored on DANS, and can be used to study word characteristics or literary reading and all facets of eye movements.
  • Manhardt, F., Brouwer, S., & Ozyurek, A. (2021). A tale of two modalities: Sign and speech influence in each other in bimodal bilinguals. Psychological Science, 32(3), 424-436. doi:10.1177/0956797620968789.

    Abstract

    Bimodal bilinguals are hearing individuals fluent in a sign and a spoken language. Can the two languages influence each other in such individuals despite differences in the visual (sign) and vocal (speech) modalities of expression? We investigated cross-linguistic influences on bimodal bilinguals’ expression of spatial relations. Unlike spoken languages, sign uses iconic linguistic forms that resemble physical features of objects in a spatial relation and thus expresses specific semantic information. Hearing bimodal bilinguals (n = 21) fluent in Dutch and Sign Language of the Netherlands and their hearing nonsigning and deaf signing peers (n = 20 each) described left/right relations between two objects. Bimodal bilinguals expressed more specific information about physical features of objects in speech than nonsigners, showing influence from sign language. They also used fewer iconic signs with specific semantic information than deaf signers, demonstrating influence from speech. Bimodal bilinguals’ speech and signs are shaped by two languages from different modalities.

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  • Marklund, P., Fransson, P., Cabeza, R., Petersson, K. M., Ingvar, M., & Nyberg, L. (2007). Sustained and transient neural modulations in prefrontal cortex related to declarative long-term memory, working memory, and attention. Cortex, 43(1), 22-37. doi:10.1016/S0010-9452(08)70443-X.

    Abstract

    Common activations in prefrontal cortex (PFC) during episodic and semantic long-term memory (LTM) tasks have been hypothesized to reflect functional overlap in terms of working memory (WM) and cognitive control. To evaluate a WM account of LTM-general activations, the present study took into consideration that cognitive task performance depends on the dynamic operation of multiple component processes, some of which are stimulus-synchronous and transient in nature; and some that are engaged throughout a task in a sustained fashion. PFC and WM may be implicated in both of these temporally independent components. To elucidate these possibilities we employed mixed blocked/event-related functional magnetic resonance imaging (fMRI) procedures to assess the extent to which sustained or transient activation patterns overlapped across tasks indexing episodic and semantic LTM, attention (ATT), and WM. Within PFC, ventrolateral and medial areas exhibited sustained activity across all tasks, whereas more anterior regions including right frontopolar cortex were commonly engaged in sustained processing during the three memory tasks. These findings do not support a WM account of sustained frontal responses during LTM tasks, but instead suggest that the pattern that was common to all tasks reflects general attentional set/vigilance, and that the shared WM-LTM pattern mediates control processes related to upholding task set. Transient responses during the three memory tasks were assessed relative to ATT to isolate item-specific mnemonic processes and were found to be largely distinct from sustained effects. Task-specific effects were observed for each memory task. In addition, a common item response for all memory tasks involved left dorsolateral PFC (DLPFC). The latter response might be seen as reflecting WM processes during LTM retrieval. Thus, our findings suggest that a WM account of shared PFC recruitment in LTM tasks holds for common transient item-related responses rather than sustained state-related responses that are better seen as reflecting more general attentional/control processes.
  • McConnell, K., & Blumenthal-Dramé, A. (2021). Usage-Based Individual Differences in the Probabilistic Processing of Multi-Word Sequences. Frontiers in Communication, 6: 703351. doi:10.3389/fcomm.2021.703351.

    Abstract

    While it is widely acknowledged that both predictive expectations and retrodictive
    integration influence language processing, the individual differences that affect these
    two processes and the best metrics for observing them have yet to be fully described.
    The present study aims to contribute to the debate by investigating the extent to which
    experienced-based variables modulate the processing of word pairs (bigrams).
    Specifically, we investigate how age and reading experience correlate with lexical
    anticipation and integration, and how this effect can be captured by the metrics of
    forward and backward transition probability (TP). Participants read more and less
    strongly associated bigrams, paired to control for known lexical covariates such as
    bigram frequency and meaning (i.e., absolute control, total control, absolute silence,
    total silence) in a self-paced reading (SPR) task. They additionally completed
    assessments of exposure to print text (Author Recognition Test, Shipley vocabulary
    assessment, Words that Go Together task) and provided their age. Results show that
    both older age and lesser reading experience individually correlate with stronger TP
    effects. Moreover, TP effects differ across the spillover region (the two words following
    the noun in the bigram)
  • McQueen, J. M., & Viebahn, M. C. (2007). Tracking recognition of spoken words by tracking looks to printed words. Quarterly Journal of Experimental Psychology, 60(5), 661-671. doi:10.1080/17470210601183890.

    Abstract

    Eye movements of Dutch participants were tracked as they looked at arrays of four words on a computer screen and followed spoken instructions (e.g., "Klik op het woord buffel": Click on the word buffalo). The arrays included the target (e.g., buffel), a phonological competitor (e.g., buffer, buffer), and two unrelated distractors. Targets were monosyllabic or bisyllabic, and competitors mismatched targets only on either their onset or offset phoneme and only by one distinctive feature. Participants looked at competitors more than at distractors, but this effect was much stronger for offset-mismatch than onset-mismatch competitors. Fixations to competitors started to decrease as soon as phonetic evidence disfavouring those competitors could influence behaviour. These results confirm that listeners continuously update their interpretation of words as the evidence in the speech signal unfolds and hence establish the viability of the methodology of using eye movements to arrays of printed words to track spoken-word recognition.
  • McQueen, J. M., Norris, D., & Cutler, A. (1999). Lexical influence in phonetic decision-making: Evidence from subcategorical mismatches. Journal of Experimental Psychology: Human Perception and Performance, 25, 1363-1389. doi:10.1037/0096-1523.25.5.1363.

    Abstract

    In 5 experiments, listeners heard words and nonwords, some cross-spliced so that they contained acoustic-phonetic mismatches. Performance was worse on mismatching than on matching items. Words cross-spliced with words and words cross-spliced with nonwords produced parallel results. However, in lexical decision and 1 of 3 phonetic decision experiments, performance on nonwords cross-spliced with words was poorer than on nonwords cross-spliced with nonwords. A gating study confirmed that there were misleading coarticulatory cues in the cross-spliced items; a sixth experiment showed that the earlier results were not due to interitem differences in the strength of these cues. Three models of phonetic decision making (the Race model, the TRACE model, and a postlexical model) did not explain the data. A new bottom-up model is outlined that accounts for the findings in terms of lexical involvement at a dedicated decision-making stage.
  • McQueen, J. M., & Cutler, A. (2001). Spoken word access processes: An introduction. Language and Cognitive Processes, 16, 469-490. doi:10.1080/01690960143000209.

    Abstract

    We introduce the papers in this special issue by summarising the current major issues in spoken word recognition. We argue that a full understanding of the process of lexical access during speech comprehension will depend on resolving several key representational issues: what is the form of the representations used for lexical access; how is phonological information coded in the mental lexicon; and how is the morphological and semantic information about each word stored? We then discuss a number of distinct access processes: competition between lexical hypotheses; the computation of goodness-of-fit between the signal and stored lexical knowledge; segmentation of continuous speech; whether the lexicon influences prelexical processing through feedback; and the relationship of form-based processing to the processes responsible for deriving an interpretation of a complete utterance. We conclude that further progress may well be made by swapping ideas among the different sub-domains of the discipline.
  • McQueen, J. M., Otake, T., & Cutler, A. (2001). Rhythmic cues and possible-word constraints in Japanese speech segmentation. Journal of Memory and Language, 45, 103-132. doi:10.1006/jmla.2000.2763.

    Abstract

    In two word-spotting experiments, Japanese listeners detected Japanese words faster in vowel contexts (e.g., agura, to sit cross-legged, in oagura) than in consonant contexts (e.g., tagura). In the same experiments, however, listeners spotted words in vowel contexts (e.g., saru, monkey, in sarua) no faster than in moraic nasal contexts (e.g., saruN). In a third word-spotting experiment, words like uni, sea urchin, followed contexts consisting of a consonant-consonant-vowel mora (e.g., gya) plus either a moraic nasal (gyaNuni), a vowel (gyaouni) or a consonant (gyabuni). Listeners spotted words as easily in the first as in the second context (where in each case the target words were aligned with mora boundaries), but found it almost impossible to spot words in the third (where there was a single consonant, such as the [b] in gyabuni, between the beginning of the word and the nearest preceding mora boundary). Three control experiments confirmed that these effects reflected the relative ease of segmentation of the words from their contexts.We argue that the listeners showed sensitivity to the viability of sound sequences as possible Japanese words in the way that they parsed the speech into words. Since single consonants are not possible Japanese words, the listeners avoided lexical parses including single consonants and thus had difficulty recognizing words in the consonant contexts. Even though moraic nasals are also impossible words, they were not difficult segmentation contexts because, as with the vowel contexts, the mora boundaries between the contexts and the target words signaled likely word boundaries. Moraic rhythm appears to provide Japanese listeners with important segmentation cues.
  • Melnychuk, T., Galke, L., Seidlmayer, E., Förster, K. U., Tochtermann, K., & Schultz, C. (2021). Früherkennung wissenschaftlicher Konvergenz im Hochschulmanagement. Hochschulmanagement, 16(1), 24-28.

    Abstract

    It is crucial for universities to recognize early signals of scientific convergence. Scientific convergence describes a dynamic pattern where the distance between different fields of knowledge shrinks over time. This knowledge
    space is beneficial to radical innovations and new promising research topics. Research in converging areas of knowledge can therefore allow universities to establish a leading position in the science community.
    The Q-AKTIV project develops a new approach on the basis of machine learning to identify scientific convergence at an early stage. In this work, we briefly present this approach and the first results of empirical validation. We discuss the benefits of an instrument building on our approach for the strategic management of universities and
    other research institutes.
  • Menenti, L., & Burani, C. (2007). What causes the effect of age of acquisition in lexical processing? Quarterly Journal of Experimental Psychology, 60(5), 652-660. doi:10.1080/17470210601100126.

    Abstract

    Three hypotheses for effects of age of acquisition (AoA) in lexical processing are compared: the cumulative frequency hypothesis (frequency and AoA both influence the number of encounters with a word, which influences processing speed), the semantic hypothesis (early-acquired words are processed faster because they are more central in the semantic network), and the neural network model (early-acquired words are faster because they are acquired when a network has maximum plasticity). In a regression study of lexical decision (LD) and semantic categorization (SC) in Italian and Dutch, contrary to the cumulative frequency hypothesis, AoA coefficients were larger than frequency coefficients, and, contrary to the semantic hypothesis, the effect of AoA was not larger in SC than in LD. The neural network model was supported.
  • Menks, W. M., Fehlbaum, L. V., Borbás, R., Sterzer, P., Stadler, C., & Raschle, N. M. (2021). Eye gaze patterns and functional brain responses during emotional face processing in adolescents with conduct disorder. NeuroImage: Clinical, 29: 102519. doi:10.1016/j.nicl.2020.102519.

    Abstract

    Background: Conduct disorder (CD) is characterized by severe aggressive and antisocial behavior. Initial evidence
    suggests neural deficits and aberrant eye gaze pattern during emotion processing in CD; both concepts, however,
    have not yet been studied simultaneously. The present study assessed the functional brain correlates of emotional
    face processing with and without consideration of concurrent eye gaze behavior in adolescents with CD
    compared to typically developing (TD) adolescents.
    Methods: 58 adolescents (23CD/35TD; average age = 16 years/range = 14–19 years) underwent an implicit
    emotional face processing task. Neuroimaging analyses were conducted for a priori-defined regions of interest
    (insula, amygdala, and medial orbitofrontal cortex) and using a full-factorial design assessing the main effects of
    emotion (neutral, anger, fear), group and the interaction thereof (cluster-level, p < .05 FWE-corrected) with and
    without consideration of concurrent eye gaze behavior (i.e., time spent on the eye region).
    Results: Adolescents with CD showed significant hypo-activations during emotional face processing in right
    anterior insula compared to TD adolescents, independent of the emotion presented. In-scanner eye-tracking data
    revealed that adolescents with CD spent significantly less time on the eye, but not mouth region. Correcting for
    eye gaze behavior during emotional face processing reduced group differences previously observed for right
    insula.
    Conclusions: Atypical insula activation during emotional face processing in adolescents with CD may partly be
    explained by attentional mechanisms (i.e., reduced gaze allocation to the eyes, independent of the emotion
    presented). An increased understanding of the mechanism causal for emotion processing deficits observed in CD
    may ultimately aid the development of personalized intervention programs

    Additional information

    1-s2.0-S2213158220303569-mmc1.doc
  • He, J., Meyer, A. S., Creemers, A., & Brehm, L. (2021). Conducting language production research online: A web-based study of semantic context and name agreement effects in multi-word production. Collabra: Psychology, 7(1): 29935. doi:10.1525/collabra.29935.

    Abstract

    Few web-based experiments have explored spoken language production, perhaps due to concerns of data quality, especially for measuring onset latencies. The present study highlights how speech production research can be done outside of the laboratory by measuring utterance durations and speech fluency in a multiple-object naming task when examining two effects related to lexical selection: semantic context and name agreement. A web-based modified blocked-cyclic naming paradigm was created, in which participants named a total of sixteen simultaneously presented pictures on each trial. The pictures were either four tokens from the same semantic category (homogeneous context), or four tokens from different semantic categories (heterogeneous context). Name agreement of the pictures was varied orthogonally (high, low). In addition to onset latency, five dependent variables were measured to index naming performance: accuracy, utterance duration, total pause time, the number of chunks (word groups pronounced without intervening pauses), and first chunk length. Bayesian analyses showed effects of semantic context and name agreement for some of the dependent measures, but no interaction. We discuss the methodological implications of the current study and make best practice recommendations for spoken language production research in an online environment.
  • He, J., Meyer, A. S., & Brehm, L. (2021). Concurrent listening affects speech planning and fluency: The roles of representational similarity and capacity limitation. Language, Cognition and Neuroscience, 36(10), 1258-1280. doi:10.1080/23273798.2021.1925130.

    Abstract

    In a novel continuous speaking-listening paradigm, we explored how speech planning was affected by concurrent listening. In Experiment 1, Dutch speakers named pictures with high versus low name agreement while ignoring Dutch speech, Chinese speech, or eight-talker babble. Both name agreement and type of auditory input influenced response timing and chunking, suggesting that representational similarity impacts lexical selection and the scope of advance planning in utterance generation. In Experiment 2, Dutch speakers named pictures with high or low name agreement while either ignoring Dutch words, or attending to them for a later memory test. Both name agreement and attention demand influenced response timing and chunking, suggesting that attention demand impacts lexical selection and the planned utterance units in each response. The study indicates that representational similarity and attention demand play important roles in linguistic dual-task interference, and the interference can be managed by adapting when and how to plan speech.

    Additional information

    supplemental material
  • Meyer, A. S., & Damian, M. F. (2007). Activation of distractor names in the picture-picture interference paradigm. Memory & Cognition, 35, 494-503.

    Abstract

    In four experiments, participants named target pictures that were accompanied by distractor pictures with phonologically related or unrelated names. Across experiments, the type of phonological relationship between the targets and the related distractors was varied: They were homophones (e.g., bat [animal/baseball]), or they shared word-initial segments (e.g., dog-doll) or word-final segments (e.g., ball-wall). The participants either named the objects after an extensive familiarization and practice phase or without any familiarization or practice. In all of the experiments, the mean target-naming latency was shorter in the related than in the unrelated condition, demonstrating that the phonological form of the name of the distractor picture became activated. These results are best explained within a cascaded model of lexical access—that is, under the assumption that the recognition of an object leads to the activation of its name.
  • Meyer, A. S. (1997). Conceptual influences on grammatical planning units. Language and Cognitive Processes, 12, 859-863. doi:10.1080/016909697386745.
  • Meyer, A. S., Belke, E., Telling, A. L., & Humphreys, G. W. (2007). Early activation of object names in visual search. Psychonomic Bulletin & Review, 14, 710-716.

    Abstract

    In a visual search experiment, participants had to decide whether or not a target object was present in a four-object search array. One of these objects could be a semantically related competitor (e.g., shirt for the target trousers) or a conceptually unrelated object with the same name as the target-for example, bat (baseball) for the target bat (animal). In the control condition, the related competitor was replaced by an unrelated object. The participants' response latencies and eye movements demonstrated that the two types of related competitors had similar effects: Competitors attracted the participants' visual attention and thereby delayed positive and negative decisions. The results imply that semantic and name information associated with the objects becomes rapidly available and affects the allocation of visual attention.
  • Meyer, A. S., & Levelt, W. J. M. (2000). Merging speech perception and production [Comment on Norris, McQueen and Cutler]. Behavioral and Brain Sciences, 23(3), 339-340. doi:10.1017/S0140525X00373241.

    Abstract

    A comparison of Merge, a model of comprehension, and WEAVER, a model of production, raises five issues: (1) merging models of comprehension and production necessarily creates feedback; (2) neither model is a comprehensive account of word processing; (3) the models are incomplete in different ways; (4) the models differ in their handling of competition; (5) as opposed to WEAVER, Merge is a model of metalinguistic behavior.
  • Meyer, A. S., & Van der Meulen, F. (2000). Phonological priming effects on speech onset latencies and viewing times in object naming. Psychonomic Bulletin & Review, 7, 314-319.
  • Meyer, A. S., & Bock, K. (1999). Representations and processes in the production of pronouns: Some perspectives from Dutch. Journal of Memory and Language, 41(2), 281-301. doi:doi:10.1006/jmla.1999.2649.

    Abstract

    The production and interpretation of pronouns involves the identification of a mental referent and, in connected speech or text, a discourse antecedent. One of the few overt signals of the relationship between a pronoun and its antecedent is agreement in features such as number and grammatical gender. To examine how speakers create these signals, two experiments tested conceptual, lexical. and morphophonological accounts of pronoun production in Dutch. The experiments employed sentence completion and continuation tasks with materials containing noun phrases that conflicted or agreed in grammatical gender. The noun phrases served as the antecedents for demonstrative pronouns tin Experiment 1) and relative pronouns tin Experiment 2) that required gender marking. Gender errors were used to assess the nature of the processes that established the link between pronouns and antecedents. There were more gender errors when candidate antecedents conflicted in grammatical gender, counter to the predictions of a pure conceptual hypothesis. Gender marking on candidate antecedents did not change the magnitude of this interference effect, counter to the predictions of an overt-morphology hypothesis. Mirroring previous findings about pronoun comprehension, the results suggest that speakers of gender-marking languages call on specific linguistic information about antecedents in order to select pronouns and that the information consists of specifications of grammatical gender associated with the lemmas of words.
  • Meyer, A. S., Belke, E., Häcker, C., & Mortensen, L. (2007). Use of word length information in utterance planning. Journal of Memory and Language, 57, 210-231. doi:10.1016/j.jml.2006.10.005.

    Abstract

    Griffin [Griffin, Z. M. (2003). A reversed length effect in coordinating the preparation and articulation of words in speaking. Psychonomic Bulletin & Review, 10, 603-609.] found that speakers naming object pairs spent more time before utterance onset looking at the second object when the first object name was short than when it was long. She proposed that this reversed length effect arose because the speakers' decision when to initiate an utterance was based, in part, on their estimate of the spoken duration of the first object name and the time available during its articulation to plan the second object name. In Experiment I of the present study, participants named object pairs. They spent more time looking at the first object when its name was monosyllabic than when it was trisyllabic, and, as in Griffin's study, the average gaze-speech lag (the time between the end of the gaze to the first object and onset of its name, which corresponds closely to the pre-speech inspection time for the second object) showed a reversed length effect. Experiments 2 and 3 showed that this effect was not due to a trade-off between the time speakers spent looking at the first and second object before speech onset. Experiment 4 yielded a reversed length effect when the second object was replaced by a symbol (x or +), which the participants had to categorise. We propose a novel account of the reversed length effect, which links it to the incremental nature of phonological encoding and articulatory planning rather than the speaker's estimate of the length of the first object name.
  • Mickan, A., McQueen, J. M., Valentini, B., Piai, V., & Lemhöfer, K. (2021). Electrophysiological evidence for cross-language interference in foreign-language attrition. Neuropsychologia, 155: 107795. doi:10.1016/j.neuropsychologia.2021.107795.

    Abstract

    Foreign language attrition (FLA) appears to be driven by interference from other, more recently-used languages (Mickan et al., 2020). Here we tracked these interference dynamics electrophysiologically to further our understanding of the underlying processes. Twenty-seven Dutch native speakers learned 70 new Italian words over two days. On a third day, EEG was recorded as they performed naming tasks on half of these words in English and, finally, as their memory for all the Italian words was tested in a picture-naming task. Replicating Mickan et al., recall was slower and tended to be less complete for Italian words that were interfered with (i.e., named in English) than for words that were not. These behavioral interference effects were accompanied by an enhanced frontal N2 and a decreased late positivity (LPC) for interfered compared to not-interfered items. Moreover, interfered items elicited more theta power. We also found an increased N2 during the interference phase for items that participants were later slower to retrieve in Italian. We interpret the N2 and theta effects as markers of interference, in line with the idea that Italian retrieval at final test is hampered by competition from recently practiced English translations. The LPC, in turn, reflects the consequences of interference: the reduced accessibility of interfered Italian labels. Finally, that retrieval ease at final test was related to the degree of interference during previous English retrieval shows that FLA is already set in motion during the interference phase, and hence can be the direct consequence of using other languages.

    Additional information

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  • Misersky, J., Slivac, K., Hagoort, P., & Flecken, M. (2021). The State of the Onion: Grammatical aspect modulates object representation during event comprehension. Cognition, 214: 104744. doi:10.1016/j.cognition.2021.104744.

    Abstract

    The present ERP study assessed whether grammatical aspect is used as a cue in online event comprehension, in particular when reading about events in which an object is visually changed. While perfective aspect cues holistic event representations, including an event's endpoint, progressive aspect highlights intermediate phases of an event. In a 2 × 3 design, participants read SVO sentences describing a change-of-state event (e.g., to chop an onion), with grammatical Aspect manipulated (perfective “chopped” vs progressive “was chopping”). Thereafter, they saw a Picture of an object either having undergone substantial state-change (SC; a chopped onion), no state-change (NSC; an onion in its original state) or an unrelated object (U; a cactus, acting as control condition). Their task was to decide whether the object in the Picture was mentioned in the sentence. We focused on N400 modulation, with ERPs time-locked to picture onset. U pictures elicited an N400 response as expected, suggesting detection of categorical mismatches in object type. For SC and NSC pictures, a whole-head follow-up analysis revealed a P300, implying people were engaged in detailed evaluation of pictures of matching objects. SC pictures received most positive responses overall. Crucially, there was an interaction of Aspect and Picture: SC pictures resulted in a higher amplitude P300 after sentences in the perfective compared to the progressive. Thus, while the perfective cued for a holistic event representation, including the resultant state of the affected object (i.e., the chopped onion) constraining object representations online, the progressive defocused event completion and object-state change. Grammatical aspect thus guided online event comprehension by cueing the visual representation(s) of an object's state.
  • Misra, S. (2021). Real-time dynamic fur and hair simulation using verlet integration. International Journal of Scientific and Research Publication (IJSRP), 11(2), 444-450. doi:10.29322/IJSRP.11.02.2021.p11053.

    Abstract

    Throughout the history of game development, the physics behind the real-time hair simulation has continued to pose a challenge due to lack of availability of computational resources required by the system. Unlike rendering an animation, where the requirement of real-time simulation is absent, game hair physics needs more efficiency when it comes to utilization of computational resources. Generally, for making a hair strand mesh, a cylinder or a capsule mesh is an obvious choice despite its requirement of a higher number of draw calls or resources. This paper proposes the use of an innovative and highly efficient use of quad polygons, whose normals face the render in conjunction with the use of Verlet integration, which delivers optimal results by keeping the frames per second (FPS) stable. Additionally, the proposed physics also allows for physical forces, such as gravity and wind, to affect hair movement as well as simulate a natural curl in the hair strand.
  • Monaco, A., Fisher, S. E., & The SLI Consortium (SLIC) (2007). Multivariate linkage analysis of specific language impairment (SLI). Annals of Human Genetics, 71(5), 660-673. doi:10.1111/j.1469-1809.2007.00361.x.

    Abstract

    Specific language impairment (SLI) is defined as an inability to develop appropriate language skills without explanatory medical conditions, low intelligence or lack of opportunity. Previously, a genome scan of 98 families affected by SLI was completed by the SLI Consortium, resulting in the identification of two quantitative trait loci (QTL) on chromosomes 16q (SLI1) and 19q (SLI2). This was followed by a replication of both regions in an additional 86 families. Both these studies applied linkage methods to one phenotypic trait at a time. However, investigations have suggested that simultaneous analysis of several traits may offer more power. The current study therefore applied a multivariate variance-components approach to the SLI Consortium dataset using additional phenotypic data. A multivariate genome scan was completed and supported the importance of the SLI1 and SLI2 loci, whilst highlighting a possible novel QTL on chromosome 10. Further investigation implied that the effect of SLI1 on non-word repetition was equally as strong on reading and spelling phenotypes. In contrast, SLI2 appeared to have influences on a selection of expressive and receptive language phenotypes in addition to non-word repetition, but did not show linkage to literacy phenotypes.

    Additional information

    Members_SLIC.doc
  • Montero-Melis, G. (2021). Consistency in motion event encoding across languages. Frontiers in Psychology, 12: 625153. doi:10.3389/fpsyg.2021.625153.

    Abstract

    Syntactic templates serve as schemas, allowing speakers to describe complex events in a systematic fashion. Motion events have long served as a prime example of how different languages favor different syntactic frames, in turn biasing their speakers towards different event conceptualizations. However, there is also variability in how motion events are syntactically framed within languages. Here we measure the consistency in event encoding in two languages, Spanish and Swedish. We test a dominant account in the literature, namely that variability within a language can be explained by specific properties of the events. This event-properties account predicts that descriptions of one and the same event should be consistent within a language, even in languages where there is overall variability in the use of syntactic frames. Spanish and Swedish speakers (N=84) described 32 caused motion events. While the most frequent syntactic framing in each language was as expected based on typology (Spanish: verb-framed, Swedish: satellite-framed, cf. Talmy, 2000), Swedish descriptions were substantially more consistent than Spanish descriptions. Swedish speakers almost invariably encoded all events with a single syntactic frame and systematically conveyed manner of motion. Spanish descriptions, in contrast, varied much more regarding syntactic framing and expression of manner. Crucially, variability in Spanish descriptions was not mainly a function of differences between events, as predicted by the event-properties account. Rather, Spanish variability in syntactic framing was driven by speaker biases. A similar picture arose for whether Spanish descriptions expressed manner information or not: Even after accounting for the effect of syntactic choice, a large portion of the variance in Spanish manner encoding remained attributable to differences among speakers. The results show that consistency in motion event encoding starkly differs across languages: Some languages (like Swedish) bias their speakers towards a particular linguistic event schema much more than others (like Spanish). Implications of these findings are discussed with respect to the typology of event framing, theories on the relationship between language and thought, and speech planning. In addition, the tools employed here to quantify variability can be applied to other domains of language.

    Additional information

    data and analysis scripts
  • Moreno Santillán, D. D., Lama, T. M., Gutierrez Guerrero, Y. T., Brown, A. M., Donat, P., Zhao, H., Rossiter, S. J., Yohe, L. R., Potter, J. H., Teeling, E. C., Vernes, S. C., Davies, K. T. J., Myers, E., Hughes, G. M., Huang, Z., Hoffmann, F., Corthals, A. P., Ray, D. A., & Dávalos, L. M. (2021). Large‐scale genome sampling reveals unique immunity and metabolic adaptations in bats. Molecular Ecology, 30(23), 6449-6467. doi:10.1111/mec.16027.

    Abstract

    Comprising more than 1,400 species, bats possess adaptations unique among mammals including powered flight, unexpected longevity, and extraordinary immunity. Some of the molecular mechanisms underlying these unique adaptations includes DNA repair, metabolism and immunity. However, analyses have been limited to a few divergent lineages, reducing the scope of inferences on gene family evolution across the Order Chiroptera. We conducted an exhaustive comparative genomic study of 37 bat species, one generated in this study, encompassing a large number of lineages, with a particular emphasis on multi-gene family evolution across immune and metabolic genes. In agreement with previous analyses, we found lineage-specific expansions of the APOBEC3 and MHC-I gene families, and loss of the proinflammatory PYHIN gene family. We inferred more than 1,000 gene losses unique to bats, including genes involved in the regulation of inflammasome pathways such as epithelial defense receptors, the natural killer gene complex and the interferon-gamma induced pathway. Gene set enrichment analyses revealed genes lost in bats are involved in defense response against pathogen-associated molecular patterns and damage-associated molecular patterns. Gene family evolution and selection analyses indicate bats have evolved fundamental functional differences compared to other mammals in both innate and adaptive immune system, with the potential to enhance anti-viral immune response while dampening inflammatory signaling. In addition, metabolic genes have experienced repeated expansions related to convergent shifts to plant-based diets. Our analyses support the hypothesis that, in tandem with flight, ancestral bats had evolved a unique set of immune adaptations whose functional implications remain to be explored.

    Additional information

    supplementary material table S1-S18
  • Morgan, A., Braden, R., Wong, M. M. K., Colin, E., Amor, D., Liégeois, F., Srivastava, S., Vogel, A., Bizaoui, V., Ranguin, K., Fisher, S. E., & Van Bon, B. W. (2021). Speech and language deficits are central to SETBP1 haploinsufficiency disorder. European Journal of Human Genetics, 29, 1216-1225. doi:10.1038/s41431-021-00894-x.

    Abstract

    Expressive communication impairment is associated with haploinsufficiency of SETBP1, as reported in small case series. Heterozygous pathogenic loss-of-function (LoF) variants in SETBP1 have also been identified in independent cohorts ascertained for childhood apraxia of speech (CAS), warranting further investigation of the roles of this gene in speech development. Thirty-one participants (12 males, aged 0; 8–23; 2 years, 28 with pathogenic SETBP1 LoF variants, 3 with 18q12.3 deletions) were assessed for speech, language and literacy abilities. Broader development was examined with standardised motor, social and daily life skills assessments. Gross and fine motor deficits (94%) and intellectual impairments (68%) were common. Protracted and aberrant speech development was consistently seen, regardless of motor or intellectual ability. We expand the linguistic phenotype associated with SETBP1 LoF syndrome (SETBP1 haploinsufficiency disorder), revealing a striking speech presentation that implicates both motor (CAS, dysarthria) and language (phonological errors) systems, with CAS (80%) being the most common diagnosis. In contrast to past reports, the understanding of language was rarely better preserved than language expression (29%). Language was typically low, to moderately impaired, with commensurate expression and comprehension ability. Children were sociable with a strong desire to communicate. Minimally verbal children (32%) augmented speech with sign language, gestures or digital devices. Overall, relative to general development, spoken language and literacy were poorer than social, daily living, motor and adaptive behaviour skills. Our findings show that poor communication is a central feature of SETBP1 haploinsufficiency disorder, confirming this gene as a strong candidate for speech and language disorders.

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