Publications

Abstract

Individuals with attention deficit/hyperactivity disorder (ADHD) are at increased risk of developing substance use disorders (SUDs) and nicotine dependence. The co-occurrence of ADHD and SUDs/nicotine dependence may in part be mediated by shared genetic liability. Several neurobiological pathways have been implicated in both ADHD and SUDs, including dopamine and serotonin pathways. We hypothesized that variations in dopamine and serotonin neurotransmission genes were involved in the genetic liability to develop SUDs/nicotine dependence in ADHD. The current study included participants with ADHD (n = 280) who were originally part of the Dutch International Multicenter ADHD Genetics study. Participants were aged 5-15 years and attending outpatient clinics at enrollment in the study. Diagnoses of ADHD, SUDs, nicotine dependence, age of first nicotine and substance use, and alcohol use severity were based on semi-structured interviews and questionnaires. Genetic risk scores were created for both serotonergic and dopaminergic risk genes previously shown to be associated with ADHD and SUDs and/or nicotine dependence. The serotonin genetic risk score significantly predicted alcohol use severity. No significant serotonin x dopamine risk score or effect of stimulant medication was found. The current study adds to the literature by providing insight into genetic underpinnings of the co-morbidity of ADHD and SUDs. While the focus of the literature so far has been mostly on dopamine, our study suggests that serotonin may also play a role in the relationship between these disorders.

Abstract

When visual stimuli remain present during search, people spend more time fixating objects that are semantically or visually related to the target instruction than fixating unrelated objects. Are these semantic and visual biases also observable when participants search within memory? We removed the visual display prior to search while continuously measuring eye movements towards locations previously occupied by objects. The target absent trials contained objects that were either visually or semantically related to the target instruction. When the overall mean proportion of fixation time was considered, we found biases towards the location previously occupied by the target, but failed to find biases towards visually or semantically related objects. However, in two experiments, the pattern of biases towards the target over time provided a reliable predictor for biases towards the visually and semantically related objects. We therefore conclude that visual and semantic representations alone can guide eye movements in memory search, but that orienting biases are weak when the stimuli are no longer present.

Abstract

An important question is to what extent visual attention is driven by the semantics of individual objects, rather than by their visual appearance. This study investigates the hypothesis that timing is a crucial factor in the occurrence and strength of semantic influences on visual orienting. To assess the dynamics of such influences, the target instruction was presented either before or after visual stimulus onset, while eye movements were continuously recorded throughout the search. The results show a substantial but delayed bias in orienting towards semantically related objects compared to visually related objects when target instruction is presented before visual stimulus onset. However, this delay can be completely undone by presenting the visual information before the target instruction (Experiment 1). Moreover, the absence or presence of visual competition does not change the temporal dynamics of the semantic bias (Experiment 2). Visual orienting is thus driven by priority settings that dynamically shift between visual and semantic representations, with each of these types of bias operating largely independently. The findings bridge the divide between the visual attention and the psycholinguistic literature.

Abstract

Researchers in different fields of psychology have been interested in how vision and language interact, and what type of representations are involved in such interactions. We introduce a stimulus set that facilitates such research (available online). The set consists of 100 words each of which is paired with four pictures of objects: One semantically similar object (but visually dissimilar), one visually similar object (but semantically dissimilar), and two unrelated objects. Visual and semantic similarity ratings between corresponding items are provided for every picture for Dutch and for English. In addition, visual and linguistic parameters of each picture are reported. We thus present a stimulus set from which researchers can select, on the basis of various parameters, the items most optimal for their research question.

Abstract

Visual attention is biased by both visual and semantic representations activated by words. We investigated to what extent language-induced visual and semantic biases are subject to task demands. Participants memorized a spoken word for a verbal recognition task, and performed a visual search task during the retention period. Crucially, while the word had to be remembered in all conditions, it was either relevant for the search (as it also indicated the target) or irrelevant (as it only served the memory test afterwards). On critical trials, displays contained objects that were visually or semantically related to the memorized word. When the word was relevant for the search, eye movement biases towards visually related objects arose earlier and more strongly than biases towards semantically related objects. When the word was irrelevant, there was still evidence for visual and semantic biases, but these biases were substantially weaker, and similar in strength and temporal dynamics, without a visual advantage. We conclude that language-induced attentional biases are subject to task requirements.

Abstract

The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still controversial. Here we present the largest ever analysis of subcortical brain asymmetries, in a harmonized multi-site study using meta-analysis methods. Volumetric asymmetry of seven subcortical structures was assessed in 15,847 MRI scans from 52 datasets worldwide. There were sex differences in the asymmetry of the globus pallidus and putamen. Heritability estimates, derived from 1170 subjects belonging to 71 extended pedigrees, revealed that additive genetic factors influenced the asymmetry of these two structures and that of the hippocampus and thalamus. Handedness had no detectable effect on subcortical asymmetries, even in this unprecedented sample size, but the asymmetry of the putamen varied with age. Genetic drivers of asymmetry in the hippocampus, thalamus and basal ganglia may affect variability in human cognition, including susceptibility to psychiatric disorders.

Abstract

The central topic of this study is to investigate three- and four-place predicate in Yaqui, which are characterized by having multiple object arguments. As with other Southern Uto-Aztecan languages, it has been said that Yaqui follows the Primary/Secondary Object pattern (Dryer 1986). Actually, Yaqui presents three patterns: verbs like nenka ‘sell’ follow the direct–indirect object pattern, verbs like miika ‘give’ follow the primary object pattern, and verbs like chijakta ‘sprinkle’ follow the locative alternation pattern; the primary object pattern is the exclusive one found with derived verbs. This paper shows that the contrast between direct object and primary object languages is not absolute but rather one of degree, and hence two “object” selection principles are needed to explain this mixed system. The two principles are not limited to Yaqui but are found in other languages as well, including English.

Abstract

Psychology endeavors to develop theories of human capacities and behaviors on the basis of a variety of methodologies and dependent measures. We argue that one of the most divisive factors in psychological science is whether researchers choose to use computational modeling of theories (over and above data) during the scientific-inference process. Modeling is undervalued yet holds promise for advancing psychological science. The inherent demands of computational modeling guide us toward better science by forcing us to conceptually analyze, specify, and formalize intuitions that otherwise remain unexamined—what we dub open theory. Constraining our inference process through modeling enables us to build explanatory and predictive theories. Here, we present scientific inference in psychology as a path function in which each step shapes the next. Computational modeling can constrain these steps, thus advancing scientific inference over and above the stewardship of experimental practice (e.g., preregistration). If psychology continues to eschew computational modeling, we predict more replicability crises and persistent failure at coherent theory building. This is because without formal modeling we lack open and transparent theorizing. We also explain how to formalize, specify, and implement a computational model, emphasizing that the advantages of modeling can be achieved by anyone with benefit to all.

Abstract

The success of fMRI places constraints on the nature of the neural code. The fact that researchers can infer similarities between neural representations, despite fMRI’s limitations, implies that certain neural coding schemes are more likely than others. For fMRI to succeed given its low temporal and spatial resolution, the neural code must be smooth at the voxel and functional level such that similar stimuli engender similar internal representations. Through proof and simulation, we determine which coding schemes are plausible given both fMRI’s successes and its limitations in measuring neural activity. Deep neural network approaches, which have been forwarded as computational accounts of the ventral stream, are consistent with the success of fMRI, though functional smoothness breaks down in the later network layers. These results have implications for the nature of the neural code and ventral stream, as well as what can be successfully investigated with fMRI.

Abstract

Acceptability judgments are no longer acceptable as the holy grail for testing the nature of linguistic representations. Experimental and quantitative methods should be used to test theoretical claims in psycholinguistics. These methods should include not only behavior, but also the more recent possibilities to probe the neural codes for language-relevant representation

Abstract

Although the sentences that we hear or read have meaning, this does not necessarily mean that they are also true. Relatively little is known about the critical brain structures for, and the relative time course of, establishing the meaning and truth of linguistic expressions. We present electroencephalogram data that show the rapid parallel integration of both semantic and world
knowledge during the interpretation of a sentence. Data from functional magnetic resonance imaging revealed that the left inferior prefrontal cortex is involved in the integration of both meaning and world knowledge. Finally, oscillatory brain responses indicate that the brain keeps a record of what makes a sentence hard to interpret.

Abstract

In this paper a general cognitive architecture of spoken language processing is specified. This is followed by an account of how this cognitive architecture is instantiated in the human brain. Both the spatial aspects of the networks for language are discussed, as well as the temporal dynamics and the underlying neurophysiology. A distinction is proposed between networks for coding/decoding linguistic information and additional networks for getting from coded meaning to speaker meaning, i.e. for making the inferences that enable the listener to understand the intentions of the speaker

Abstract

Rhyme perception is an important predictor for future literacy. Assessing rhyme
abilities, however, commonly requires children to make explicit rhyme judgements on
single words. Here we explored whether infants already implicitly process rhymes in
natural rhyming contexts (child songs) and whether this response correlates with later
vocabulary size. In a passive listening ERP study, 10.5 month-old Dutch infants were
exposed to rhyming and non-rhyming child songs. Two types of rhyme effects were
analysed: (1) ERPs elicited by the first rhyme occurring in each song (rhyme sensitivity)
and (2) ERPs elicited by rhymes repeating after the first rhyme in each song (rhyme
repetition). Only for the latter a tentative negativity for rhymes from 0 to 200 ms
after the onset of the rhyme word was found. This rhyme repetition effect correlated
with productive vocabulary at 18 months-old, but not with any other vocabulary
measure (perception at 10.5 or 18 months-old). While awaiting future replication, the
study indicates precursors of phonological awareness already during infancy and with
ecologically valid linguistic stimuli.

Abstract

What would your ideas about language evolution be if there was only one language left on earth? Fortunately, our investigation need not be that impoverished. In the present article, we survey the state of knowledge regarding the kinds of language found among humans, the language inventory, population sizes, time depth, grammatical variation, and other relevant issues that a theory of language evolution should minimally take into account

Abstract

The coordinate system has been proposed as a fundamental and cross-culturally used spatial representation, through which people code location and direction information in the environment. Here we provided direct evidence demonstrating that daily experience with the cardinal coordinate system (i.e., east, west, north, and south) contributed to the representation of cognitive maps. Behaviorally, we found that individuals who relied more on the cardinal coordinate system for daily navigation made smaller errors in an indoor pointing task, suggesting that the cardinal coordinate system is an important element of cognitive maps. Neurally, the extent to which individuals relied on the cardinal coordinate system was positively correlated with the gray matter volume of the entorhinal cortex, suggesting that the entorhinal cortex may serve as the neuroanatomical basis of coordinate-based navigation (the entorhinal coordinate area, ECA). Further analyses on the resting-state functional connectivity revealed that the intrinsic interaction between the ECA and two hippocampal sub-regions, the subiculum and cornu ammonis, might be linked with the representation precision of cognitive maps. In sum, our study reveals an association between daily experience with the cardinal coordinate system and cognitive maps, and suggests that the ECA works in collaboration with hippocampal sub-regions to represent cognitive maps.

Abstract

Introduction: Navigation is a fundamental and multidimensional cognitive function that individuals rely on to move around the environment. In this study, we investigated the neural basis of human spatial navigation ability. Methods: A large cohort of participants (N > 200) was examined on their navigation ability behaviorally and structural and functional magnetic resonance imaging (MRI) were then used to explore the corresponding neural basis of spatial navigation. Results: The gray matter volume (GMV) of the bilateral parahippocampus (PHG), retrosplenial complex (RSC), entorhinal cortex (EC), hippocampus (HPC), and thalamus (THAL) was correlated with the participants’ self-reported navigational ability in general, and their sense of direction in particular. Further fMRI studies showed that the PHG, RSC, and EC selectively responded to visually presented scenes, whereas the HPC and THAL showed no selectivity, suggesting a functional division of labor among these regions in spatial navigation. The resting-state functional connectivity analysis further revealed a hierarchical neural network for navigation constituted by these regions, which can be further categorized into three relatively independent components (i.e., scene recognition component, cognitive map component, and the component of heading direction for locomotion, respectively). Conclusions: Our study combined multi-modality imaging data to illustrate that multiple brain regions may work collaboratively to extract, integrate, store, and orientate spatial information to guide navigation behaviors.

Abstract

Repetition appears to be part of error correction and action preparation in all domains that involve producing an action sequence. The present work contends that the ubiquity of repetition is due to its role in resolving a problem inherent to planning and retrieval of action sequences: the Problem of Retrieval. Repetitions occur when the production to perform next is not activated enough to be executed. Repetitions are helpful in this situation because the repeated action sequence activates the likely continuation. We model a corpus of natural speech using a recurrent network, with words as units of production. We show that repeated material makes upcoming words more predictable, especially when more than one word is repeated. Speakers are argued to produce multiword repetitions by using backward associations to reactivate recently produced words. The existence of multiword repetitions means that speakers must decide where to reinitiate execution from. We show that production restarts from words that have seldom occurred in a predictive preceding-word context and have often occurred utterance-initially. These results are explained by competition between preceding-context and top-down cues over the course of language learning. The proposed theory improves on structural accounts of repetition disfluencies, and integrates repetition disfluencies in language production with repetitions observed in other domains of skilled action.

Abstract

An increase in frequency of a form has been argued to result in semantic extension (Bybee, 2003; Zipf, 1949). Yet, research on the acquisition of lexical semantics suggests that a form that frequently co-occurs with a meaning gets restricted to that meaning (Xu & Tenenbaum, 2007). The current work reconciles these positions by showing that – through its effect on form accessibility – frequency causes semantic extension in production, while at the same time causing entrenchment in comprehension. Repeatedly experiencing a form paired with a specific meaning makes one more likely to re-use the form to express related meanings, while also increasing one’s confidence that the form is never used to express those meanings. Recurrent pathways of semantic change are argued to result from a tug of war between the production-side pressure to reuse easily accessible forms and the comprehension-side confidence that one has seen all possible uses of a frequent form.

Abstract

Humans are deeply affected by stories, yet it is unclear how. In this study, we explored two aspects of aesthetic experiences during narrative engagement - literariness and narrative fluctuations in appraised emotional intensity. Independent ratings of literariness and emotional intensity of two literary stories were used to predict blood-oxygen-level-dependent signal changes in 52 listeners from an existing fMRI dataset. Literariness was associated with increased activation in brain areas linked to semantic integration (left angular gyrus, supramarginal gyrus, and precuneus), and decreased activation in bilateral middle temporal cortices, associated with semantic representations and word memory. Emotional intensity correlated with decreased activation in a bilateral frontoparietal network that is often associated with controlled attention. Our results confirm a neural dissociation in processing literary form and emotional content in stories and generate new questions about the function of and interaction between attention, social cognition, and semantic systems during literary engagement and aesthetic experiences.

Abstract

Perspective is a crucial feature for communicating about events. Yet it is unclear how linguistically encoded perspective relates to cognitive perspective taking. Here, we tested the effect of perspective taking with short literary stories. Participants listened to stories with 1st or 3rd person pronouns referring to the protagonist, while undergoing fMRI. When comparing action events with 1st and 3rd person pronouns, we found no evidence for a neural dissociation depending on the pronoun. A split sample approach based on the self-reported experience of perspective taking revealed 3 comprehension preferences. One group showed a strong 1st person preference, another a strong 3rd person preference, while a third group engaged in 1st and 3rd person perspective taking simultaneously. Comparing brain activations of the groups revealed different neural networks. Our results suggest that comprehension is perspective dependent, but not on the perspective suggested by the text, but on the reader’s (situational) preference

Abstract

Personal pronouns have been shown to influence cognitive perspective taking during comprehension. Studies using single sentences found that 3rd person pronouns facilitate the construction of a mental model from an observer’s perspective, whereas 2nd person pronouns support an actor’s perspective. The direction of the effect for 1st person pronouns seems to depend on the situational context. In the present study, we investigated how personal pronouns influence discourse comprehension when people read fiction stories and if this has consequences for affective components like emotion during reading or appreciation of the story. We wanted to find out if personal pronouns affect immersion and arousal, as well as appreciation of fiction. In a natural reading paradigm, we measured electrodermal activity and story immersion, while participants read literary stories with 1st and 3rd person pronouns referring to the protagonist. In addition, participants rated and ranked the stories for appreciation. Our results show that stories with 1st person pronouns lead to higher immersion. Two factors—transportation into the story world and mental imagery during reading—in particular showed higher scores for 1st person as compared to 3rd person pronoun stories. In contrast, arousal as measured by electrodermal activity seemed tentatively higher for 3rd person pronoun stories. The two measures of appreciation were not affected by the pronoun manipulation. Our findings underscore the importance of perspective for language processing, and additionally show which aspects of the narrative experience are influenced by a change in perspective.

Abstract

Experiments have shown that compared to fictional texts, readers read factual texts faster and have better memory for described situations. Reading fictional texts on the other hand seems to improve memory for exact wordings and expressions. Most of these studies used a ‘newspaper’ versus ‘literature’ comparison. In the present study, we investigated the effect of reader’s expectation to whether information is true or fictional with a subtler manipulation by labelling short stories as either based on true or fictional events. In addition, we tested whether narrative perspective or individual preference in perspective taking affects reading true or fictional stories differently. In an online experiment, participants (final N=1742) read one story which was introduced as based on true events or as fictional (factor fictionality). The story could be narrated in either 1st or 3rd person perspective (factor perspective). We measured immersion in and appreciation of the story, perspective taking, as well as memory for events. We found no evidence that knowing a story is fictional or based on true events influences reading behavior or experiential aspects of reading. We suggest that it is not whether a story is true or fictional, but rather expectations towards certain reading situations (e.g. reading newspaper or literature) which affect behavior by activating appropriate reading goals. Results further confirm that narrative perspective partially influences perspective taking and experiential aspects of reading

Abstract

The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biological, social, and environmental factors is limited. To address this, we designed the Healthy Brain Study (HBS), an interdisciplinary, longitudinal, cohort study based on multidimensional, dynamic assessments in both the laboratory and the real world. Here, we describe the rationale and design of the currently ongoing HBS. The HBS is examining a population-based sample of 1,000 healthy participants (age 30-39) who are thoroughly studied across an entire year. Data are collected through cognitive, affective, behavioral, and physiological testing, neuroimaging, bio-sampling, questionnaires, ecological momentary assessment, and real-world assessments using wearable devices. These data will become an accessible resource for the scientific community enabling the next step in understanding the human brain and how it dynamically and individually operates in its bio-social context. An access procedure to the collected data and bio-samples is in place and published on https://www.healthybrainstudy.nl/en/data-and-methods.

https://www.trialregister.nl/trial/7955

Abstract

We advance the hypothesis here that the higher-than-average vocal pitch (FO) found for speech of Broca's aphasics in experimental settings is due, in part, to increased psychological stress. Two experiments were conducted which manipulated conversational constraints and the sentence forms to be produced by aphasic patients. Our study revealed significant differences between changes in vocal pitch of agrammatic Broca's aphasics versus those of Wernicke's aphasics and normal controls. It is suggested that the greater psychological stress experienced by the Broca's aphasics, but not by the Wernicke's aphasics, accounts for these observed differences.

Abstract

Second language (L2) learners frequently encounter persistent difficulty in perceiving certain non-native sound contrasts, i.e., a phenomenon called “phonological deafness”. However, if extensive L2 experience leads to neuroplastic changes in the phonological system, then the capacity to discriminate non-native phonemic contrasts should progressively improve. Such perceptual changes should be attested by modifications at the neurophysiological level. We designed an EEG experiment in which the listeners’ perceptual capacities to discriminate second language phonemic contrasts influence the processing of lexical-semantic violations. Semantic congruency of critical words in a sentence context was driven by a phonemic contrast that was unique to the L2, English (e.g.,/ɪ/-/i:/, ship – sheep). Twenty-eight young adult native speakers of French with intermediate proficiency in English listened to sentences that contained either a semantically congruent or incongruent critical word (e.g., The anchor of the ship/*sheep was let down) while EEG was recorded. Three ERP effects were found to relate to increasing L2 proficiency: (1) a left frontal auditory N100 effect, (2) a smaller fronto-central phonological mismatch negativity (PMN) effect and (3) a semantic N400 effect. No effect of proficiency was found on oscillatory markers. The current findings suggest that neuronal plasticity in the human brain allows for the late acquisition of even hard-wired linguistic features such as the discrimination of phonemic contrasts in a second language. This is the first time that behavioral and neurophysiological evidence for the critical role of neural plasticity underlying L2 phonological processing and its interdependence with semantic processing has been provided. Our data strongly support the idea that pieces of information from different levels of linguistic processing (e.g., phonological, semantic) strongly interact and influence each other during online language processing.

Abstract

In the present electroencephalographical study, we asked to which extent executive control processes are shared by both the language and motor domain. The rationale was to examine whether executive control processes whose efficiency is reinforced by the frequent use of a second language can lead to a benefit in the control of eye movements, i.e. a non-linguistic activity. For this purpose, we administrated to 19 highly proficient late French-German bilingual participants and to a control group of 20 French monolingual participants an antisaccade task, i.e. a specific motor task involving control. In this task, an automatic saccade has to be suppressed while a voluntary eye movement in the opposite direction has to be carried out. Here, our main hypothesis is that an advantage in the antisaccade task should be observed in the bilinguals if some properties of the control processes are shared between linguistic and motor domains. ERP data revealed clear differences between bilinguals and monolinguals. Critically, we showed an increased N2 effect size in bilinguals, thought to reflect better efficiency to monitor conflict, combined with reduced effect sizes on markers reflecting inhibitory control, i.e. cue-locked positivity, the target-locked P3 and the saccade-locked presaccadic positivity (PSP). Moreover, effective connectivity analyses (dynamic causal modelling; DCM) on the neuronal source level indicated that bilinguals rely more strongly on ACC-driven control while monolinguals rely on PFC-driven control. Taken together, our combined ERP and effective connectivity findings may reflect a dynamic interplay between strengthened conflict monitoring, associated with subsequently more efficient inhibition in bilinguals. Finally, L2 proficiency and immersion experience constitute relevant factors of the language background that predict efficiency of inhibition. To conclude, the present study provided ERP and effective connectivity evidence for domain-general executive control involvement in handling multiple language use, leading to a control advantage in bilingualism.

Abstract

Obesity is a genetically heterogeneous disorder. Using targeted and whole-exome sequencing, we studied 32 human and 87 rodent obesity genes in 2,548 severely obese children and 1,117 controls. We identified 52 variants contributing to obesity in 2% of cases including multiple novel variants in GNAS, which were sometimes found with accelerated growth rather than short stature as described previously. Nominally significant associations were found for rare functional variants in BBS1, BBS9, GNAS, MKKS, CLOCK and ANGPTL6. The p.S284X variant in ANGPTL6 drives the association signal (rs201622589, MAF~0.1%, odds ratio = 10.13, p-value = 0.042) and results in complete loss of secretion in cells. Further analysis including additional case-control studies and population controls (N = 260,642) did not support association of this variant with obesity (odds ratio = 2.34, p-value = 2.59 × 10−3), highlighting the challenges of testing rare variant associations and the need for very large sample sizes. Further validation in cohorts with severe obesity and engineering the variants in model organisms will be needed to explore whether human variants in ANGPTL6 and other genes that lead to obesity when deleted in mice, do contribute to obesity. Such studies may yield druggable targets for weight loss therapies.

Abstract

In this perspective paper, we focus on the study of synchronization abilities across the animal kingdom. We propose an ecological approach to studying nonhuman animal synchronization that begins from observations about when, how and why an animal might synchronize spontaneously with natural environmental rhythms. We discuss what we consider to be the most important, but thus far largely understudied, temporal, physical, perceptual and motivational constraints that must be taken into account when designing experiments to test synchronization in nonhuman animals. First and foremost, different species are likely to be sensitive to and therefore capable of synchronizing at different timescales. We also argue that it is fruitful to consider the latent flexibility of animal synchronization. Finally, we discuss the importance of an animal's motivational state for showcasing synchronization abilities. We demonstrate that the likelihood that an animal can successfully synchronize with an environmental rhythm is context-dependent and suggest that the list of species capable of synchronization is likely to grow when tested with ecologically honest, species-tuned experiments.

Abstract

Acoustic analyses can be powerful tools for illuminating structure within and between populations, especially for cryptic or difficult to access taxa. Acoustic repertoires are often compared using aggregate similarity measures across all calls of a particular type, but specific group identity calls may more clearly delineate structure in some taxa.
2. We present a new method—the identity call method—that estimates the number of acoustically distinct subdivisions in a set of repertoires and identifies call types that characterize those subdivisions. The method uses contaminated mixture models to identify call types, assigning each call a probability of belonging to each type. Repertoires are hierarchically clustered based on similarities in call type usage, producing a dendrogram with ‘identity clades’ of repertoires and the
‘identity calls’ that best characterize each clade. We validated this approach using acoustic data from sperm whales, grey-breasted wood-wrens and Australian field crickets, and ran a suite of tests to assess parameter sensitivity.
3. For all taxa, the method detected diagnostic signals (identity calls) and structure (identity clades; sperm whale subpopulations, wren subspecies and cricket species) that were consistent with past research. Some datasets were more sensitive to parameter variation than others, which may reflect real uncertainty or biological variability in the taxa examined. We recommend that users perform comparative analyses of different parameter combinations to determine which portions of the dendrogram warrant careful versus confident interpretation.
4. The presence of group-characteristic identity calls does not necessarily mean animals perceive them as such. Fine-scale experiments like playbacks are a key next step to understand call perception and function. This method can help inform such studies by identifying calls that may be salient to animals and are good candidates for investigation or playback stimuli. For cryptic or difficult to access taxa with group-specific calls, the identity call method can aid managers in quantifying behavioural diversity and/or identifying putative structure within and between
populations, given that acoustic data can be inexpensive and minimally invasive to collect.

Abstract

Simultaneous interpretation is a complex cognitive task that not only demands multilingual language processing, but also requires application of extreme levels of domain-general cognitive control. We used MRI to longitudinally measure cortical thickness in simultaneous interpretation trainees before and after a Master's program in conference interpreting. We compared them to multilingual control participants scanned at the same interval of time. Increases in cortical thickness were specific to trainee interpreters. Increases were observed in regions involved in lower-level, phonetic processing (left posterior superior temporal gyrus, anterior supramarginal gyrus and planum temporale), in the higher-level formulation of propositional speech (right angular gyrus) and in the conversion of items from working memory into a sequence (right dorsal premotor cortex), and finally, in domain-general executive control and attention (right parietal lobule). Findings are consistent with the linguistic requirements of simultaneous interpretation and also with the more general cognitive demands on attentional control for expert performance in simultaneous interpreting. Our findings may also reflect beneficial, potentially protective effects of simultaneous interpretation training, which has previously been shown to confer enhanced skills in certain executive and attentional domains over and above those conferred by bilingualism.

Abstract

The ability to predict upcoming actions is a hallmark of cognition. It remains unclear, however, whether the predictive behaviour observed in controlled lab environments generalises to rich, everyday settings. In four virtual reality experiments, we tested whether a well-established marker of linguistic prediction (anticipatory eye movements) replicated when increasing the naturalness of the paradigm by means of immersing participants in naturalistic scenes (Experiment 1), increasing the number of distractor objects (Experiment 2), modifying the proportion of predictable noun-referents (Experiment 3), and manipulating the location of referents relative to the joint attentional space (Experiment 4). Robust anticipatory eye movements were observed for Experiments 1–3. The anticipatory effect disappeared, however, in Experiment 4. Our findings suggest that predictive processing occurs in everyday communication if the referents are situated in the joint attentional space. Methodologically, our study confirms that ecological validity and experimental control may go hand-in-hand in the study of human predictive behaviour.

Abstract

The use of virtual reality (VR) as a methodological tool is becoming increasingly popular in behavioral research as its flexibility allows for a wide range of applications. This new method has not been as widely accepted in the field of psycholinguistics, however, possibly due to the assumption that language processing during human-computer interactions does not accurately reflect human-human interactions. Yet at the same time there is a growing need to study human-human language interactions in a tightly controlled context, which has not been possible using existing methods. VR, however, offers experimental control over parameters that cannot be (as finely) controlled in the real world. As such, in this study we aim to show that human-computer language interaction is comparable to human-human language interaction in virtual reality. In the current study we compare participants’ language behavior in a syntactic priming task with human versus computer partners: we used a human partner, a human-like avatar with human-like facial expressions and verbal behavior, and a computer-like avatar which had this humanness removed. As predicted, our study shows comparable priming effects between the human and human-like avatar suggesting that participants attributed human-like agency to the human-like avatar. Indeed, when interacting with the computer-like avatar, the priming effect was significantly decreased. This suggests that when interacting with a human-like avatar, sentence processing is comparable to interacting with a human partner. Our study therefore shows that VR is a valid platform for conducting language research and studying dialogue interactions in an ecologically valid manner.

Abstract

Syntactic priming, the phenomenon in which participants adopt the linguistic behaviour of their partner, is widely used in psycholinguistics to investigate syntactic operations. Although the phenomenon of syntactic priming is well documented, the memory system that supports the retention of this syntactic information long enough to influence future utterances, is not as widely investigated. We aim to shed light on this issue by assessing patients with Korsakoff's amnesia on an active-passive syntactic priming task and compare their performance to controls matched in age, education, and premorbid intelligence. Patients with Korsakoff's syndrome display deficits in all subdomains of declarative memory, yet their nondeclarative memory remains intact, making them an ideal patient group to determine which memory system supports syntactic priming. In line with the hypothesis that syntactic priming relies on nondeclarative memory, the patient group shows strong priming tendencies (12.6% passive structure repetition). Our healthy control group did not show a priming tendency, presumably due to cognitive interference between declarative and nondeclarative memory. We discuss the results in relation to amnesia, aging, and compensatory mechanisms.

Abstract

The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common neuropsychiatric disorders. To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. Of the novel loci, three lie within genes (ASTN2, DPP4 and MAST4) and one is found 200 kb upstream of SHH. A hippocampal subfield analysis shows that a locus within the MSRB3 gene shows evidence of a localized effect along the dentate gyrus, subiculum, CA1 and fissure. Further, we show that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer’s disease (rg=−0.155). Our findings suggest novel biological pathways through which human genetic variation influences hippocampal volume and risk for neuropsychiatric illness.

Abstract

Many studies have demonstrated that listeners use information extracted from verbs to guide anticipatory eye movements to objects in the visual context that satisfy the selection restrictions of the verb. An important question is what underlies such verb-mediated anticipatory eye gaze. Based on empirical and theoretical suggestions, we investigated the influence of five potential predictors of this behavior: functional associations and general associations between verb and target object, as well as the listeners’ production fluency, receptive vocabulary knowledge, and non-verbal intelligence. In three eye-tracking experiments, participants looked at sets of four objects and listened to sentences where the final word was predictable or not predictable (e.g., “The man peels/draws an apple”). On predictable trials only the target object, but not the distractors, were functionally and associatively related to the verb. In Experiments 1 and 2, objects were presented before the verb was heard. In Experiment 3, participants were given a short preview of the display after the verb was heard. Functional associations and receptive vocabulary were found to be important predictors of verb-mediated anticipatory eye gaze independent of the amount of contextual visual input. General word associations did not and non-verbal intelligence was only a very weak predictor of anticipatory eye movements. Participants’ production fluency correlated positively with the likelihood of anticipatory eye movements when participants were given the long but not the short visual display preview. These findings fit best with a pluralistic approach to predictive language processing in which multiple mechanisms, mediating factors, and situational context dynamically interact. 

Abstract

Many studies have shown that a supportive context facilitates language comprehension. A currently influential view is that language production may support prediction in language comprehension. Experimental evidence for this, however, is relatively sparse. Here we explored whether encouraging prediction in a language production task encourages the use of predictive contexts in an interleaved comprehension task. In Experiment 1a, participants listened to the first part of a sentence and provided the final word by naming aloud a picture. The picture name was predictable or not predictable from the sentence context. Pictures were named faster when they could be predicted than when this was not the case. In Experiment 1b the same sentences, augmented by a final spill-over region, were presented in a self-paced reading task. No difference in reading times for predictive vs. non-predictive sentences was found. In Experiment 2, reading and naming trials were intermixed. In the naming task, the advantage for predictable picture names was replicated. More importantly, now reading times for the spill-over region were considerable faster for predictive vs. non-predictive sentences. We conjecture that these findings fit best with the notion that prediction in the service of language production encourages the use of predictive contexts in comprehension. Further research is required to identify the exact mechanisms by which production exerts its influence on comprehension.

Abstract

Objective: To investigate the possibility of tremor detection based on deep brain activity.
Methods: We re-analyzed recordings of local field potentials (LFPs) from the subthalamic nucleus in 10
PD patients (12 body sides) with spontaneously fluctuating rest tremor. Power in several frequency bands
was estimated and used as input to Hidden Markov Models (HMMs) which classified short data segments
as either tremor-free rest or rest tremor. HMMs were compared to direct threshold application to individual
power features.
Results: Applying a threshold directly to band-limited power was insufficient for tremor detection (mean
area under the curve [AUC] of receiver operating characteristic: 0.64, STD: 0.19). Multi-feature HMMs, in
contrast, allowed for accurate detection (mean AUC: 0.82, STD: 0.15), using four power features obtained
from a single contact pair. Within-patient training yielded better accuracy than across-patient training
(0.84 vs. 0.78, p = 0.03), yet tremor could often be detected accurately with either approach. High frequency
oscillations (>200 Hz) were the best performing individual feature.
Conclusions: LFP-based markers of tremor are robust enough to allow for accurate tremor detection in
short data segments, provided that appropriate statistical models are used.
Significance: LFP-based markers of tremor could be useful control signals for closed-loop deep brain
stimulation.

Abstract

In 2 experiments, we assessed the effects of response latency and task-induced goals on the onset and time course of semantic priming during rapid processing of visual words as revealed by ocular response
tasks. In Experiment 1 (ocular lexical decision task), participants performed a lexical decision task using eye movement responses on a sequence of 4 words. In Experiment 2, the same words were encoded for an episodic recognition memory task that did not require a metalinguistic judgment. For both tasks, survival analyses showed that the earliest observable effect (divergence point [DP]) of semantic priming on target-word reading times occurred at approximately 260 ms, and ex-Gaussian distribution fits revealed that the magnitude of the priming effect increased as a function of response time. Together, these
distributional effects of semantic priming suggest that the influence of the prime increases when target processing is more effortful. This effect does not require that the task include a metalinguistic judgment;
manipulation of the task goals across experiments affected the overall response speed but not the location of the DP or the overall distributional pattern of the priming effect. These results are more readily explained as the result of a retrospective, rather than a prospective, priming mechanism and are consistent with compound-cue models of semantic priming.

Abstract

This study assessed the effects of semantic context in the form of self-produced and other-produced words on subsequent language production. Pairs of participants performed a joint picture naming task, taking turns while naming a continuous series of pictures. In the single-speaker version of this paradigm, naming latencies have been found to increase for successive presentations of exemplars from the same category, a phenomenon known as Cumulative Semantic Interference (CSI). As expected, the joint-naming task showed a within-speaker CSI effect, such that naming latencies increased as a function of the number of category exemplars named previously by the participant (self-produced items). Crucially, we also observed an across-speaker CSI effect, such that naming latencies slowed as a function of the number of category members named by the participant's task partner (other-produced items). The magnitude of the across-speaker CSI effect did not vary as a function of whether or not the listening participant could see the pictures their partner was naming. The observation of across-speaker CSI suggests that the effect originates at the conceptual level of the language system, as proposed by Belke's (2013) Conceptual Accumulation account. Whereas self-produced and other-produced words both resulted in a CSI effect on naming latencies, post-experiment free recall rates were higher for self-produced than other-produced items. Together, these results suggest that both speaking and listening result in implicit learning at the conceptual level of the language system but that these effects are independent of explicit learning as indicated by item recall.

Abstract

Comparative studies of vocal learning and vocal non-learning animals can increase our understanding of the neurobiology and evolution of vocal learning and human speech. Mammalian vocal learning is understudied: most research has either focused on vocal learning in songbirds or its absence in non-human primates. Here we focus on a highly promising model species for the neurobiology of vocal learning: grey seals. We provide a neuroanatomical atlas (based on dissected brain slices and magnetic resonance images), a labelled MRI template, a 3D model with volumetric measurements of brain regions, and histological cortical stainings. Four main features of the grey seal brain stand out. (1) It is relatively big and highly convoluted. (2) It hosts a relatively large temporal lobe and cerebellum, structures which could support developed timing abilities and acoustic processing. (3) The cortex is similar to humans in thickness and shows the expected six-layered mammalian structure. (4) Expression of FoxP2 - a gene involved in vocal learning and spoken language - is present in deeper layers of the cortex. Our results could facilitate future studies targeting the neural and genetic underpinnings of mammalian vocal learning, thus bridging the research gap from songbirds to humans and non-human primates.Competing Interest StatementThe authors have declared no competing interest.

Abstract

Conversational interaction occasionally lapses as topics become exhausted or as participants are left with no obvious thing to talk about next. In this article I look at episodes of ordinary conversation to examine how participants resolve issues of speakership and sequentiality in lapse environments. In particular, I examine one recurrent phenomenon—sequence recompletion—whereby participants bring to completion a sequence of talk that was already treated as complete. Using conversation analysis, I describe four methods for sequence recompletion: turn-exiting, action redoings, delayed replies, and post-sequence transitions. With this practice, participants use verbal and vocal resources to locally manage their participation framework when ending one course of action and potentially starting up a new one

Abstract

This article uses conversation analysis to examine constructions like who the fuck is that—sequence‐initiating actions into which an expletive like the fuck has been inserted. We describe how this turn‐constructional practice fits into and constitutes a recurrent sequence of escalating actions. In this sequence, it is used to pursue an adequate response after an inadequate one was given, and sanction the recipient for that inadequate response. Our analysis contributes to sociolinguistic studies of swearing by offering an account of swearing as a resource for social action.

Abstract

The importance of high quality teacher–student relationships for students' well-being has been long documented. Nonetheless, most studies focus either on teachers' perceptions of provided support or on students' perceptions of support. The degree to which teachers and students agree is often neither measured nor taken into account. In the current study, we will therefore use a dyadic analysis strategy called the one-with-many design. This design takes into account the nestedness of the data and looks at the importance of reciprocity when examining the influence of teacher support for students' academic and social functioning. Two samples of teachers and their students from Grade 4 (age 9–10 years) have been recruited in primary schools, located in Turkey and Romania. By using the one-with-many design we can first measure to what degree teachers' perceptions of support are in line with students' experiences. Second, this level of consensus is taken into account when examining the influence of teacher support for students' social well-being and academic functioning.

Abstract

Natural conversations are characterized by short transition times between turns. This holds in particular for multi-party conversations. The short turn transitions in everyday conversations contrast sharply with the much longer speech onset latencies observed in laboratory studies where speakers respond to spoken utterances. There are many factors that facilitate speech production in conversational compared to laboratory settings. Here we highlight one of them, the impact of competition for turns. In multi-party conversations, speakers often compete for turns. In quantitative corpus analyses of multi-party conversation, the fastest response determines the recorded turn transition time. In contrast, in dyadic conversations such competition for turns is much less likely to arise, and in laboratory experiments with individual participants it does not arise at all. Therefore, all responses tend to be recorded. Thus, competition for turns may reduce the recorded mean turn transition times in multi-party conversations for a simple statistical reason: slow responses are not included in the means. We report two studies illustrating this point. We first report the results of simulations showing how much the response times in a laboratory experiment would be reduced if, for each trial, instead of recording all responses, only the fastest responses of several participants responding independently on the trial were recorded. We then present results from a quantitative corpus analysis comparing turn transition times in dyadic and triadic conversations. There was no significant group size effect in question-response transition times, where the present speaker often selects the next one, thus reducing competition between speakers. But, as predicted, triads showed shorter turn transition times than dyads for the remaining turn transitions, where competition for the floor was more likely to arise. Together, these data show that turn transition times in conversation should be interpreted in the context of group size, turn transition type, and social setting.

Abstract

Does blinking function as a type of feedback in conversation? To address this question, we built a corpus of Dutch conversations, identified short and long addressee blinks during extended turns, and measured their occurrence relative to the end of turn constructional units (TCUs), the location
where feedback typically occurs. Addressee blinks were indeed timed to the
end of TCUs. Also, long blinks were more likely than short blinks to occur
during mutual gaze, with nods or continuers, and their occurrence was
restricted to sequential contexts in which signaling understanding was
particularly relevant, suggesting a special signaling capacity of long blinks.

Abstract

In all spoken languages, speakers use demonstratives – words like this and that – to refer to entities in their immediate environment. But which factors determine whether they use one demonstrative (this) or another (that)? Here we report the results of an experiment examining the effects of referent visibility, referent distance, and addressee location on the production of demonstratives by speakers of Ticuna (isolate; Brazil, Colombia, Peru), an Amazonian language with four demonstratives, and speakers of Dutch (Indo-European; Netherlands, Belgium), which has two demonstratives. We found that Ticuna speakers’ use of demonstratives displayed effects of addressee location and referent distance, but not referent visibility. By contrast, under comparable conditions, Dutch speakers displayed sensitivity only to referent distance. Interestingly, we also observed that Ticuna speakers consistently used demonstratives in all referential utterances in our experimental paradigm, while Dutch speakers strongly preferred to use definite articles. Taken together, these findings shed light on the significant diversity found in demonstrative systems across languages. Additionally, they invite researchers studying exophoric demonstratives to broaden their horizons by cross-linguistically investigating the factors involved in speakers’ choice of demonstratives over other types of referring expressions, especially articles.

Abstract

Form-priming effects from sublexical (syllabic or segmental) primes in masked priming can be accounted for in two ways. One is the sublexical pre-activation view according to which segments are pre-activated by the prime, and at the time the form-related target is to be produced, retrieval/assembly of those pre-activated segments is faster compared to an unrelated situation. However, it has also been argued that form-priming effects from sublexical primes might be due to lexical pre-activation. When the sublexical prime is presented, it activates all form-related words (i.e., cohorts) in the lexicon, necessarily including the form-related target, which—as a consequence—is produced faster than in the unrelated case. Note, however, that this lexical pre-activation account makes previous pre-lexical activation of segments necessary. This study reports a nonword naming experiment to investigate whether or not sublexical pre-activation is involved in masked form priming with sublexical primes. The results demonstrated a priming effect suggesting a nonlexical effect. However, this does not exclude an additional lexical component in form priming.

Abstract

During vocal communication, the spectro‑temporal structure of vocalizations conveys important
contextual information. Bats excel in the use of sounds for echolocation by meticulous encoding of
signals in the temporal domain. We therefore hypothesized that for social communication as well,
bats would excel at detecting minute distortions in the spectro‑temporal structure of calls. To test
this hypothesis, we systematically introduced spectro‑temporal distortion to communication calls of
Phyllostomus discolor bats. We broke down each call into windows of the same length and randomized
the phase spectrum inside each window. The overall degree of spectro‑temporal distortion in
communication calls increased with window length. Modelling the bat auditory periphery revealed
that cochlear mechanisms allow discrimination of fast spectro‑temporal envelopes. We evaluated
model predictions with experimental psychophysical and neurophysiological data. We first assessed
bats’ performance in discriminating original versions of calls from increasingly distorted versions of
the same calls. We further examined cortical responses to determine additional specializations for
call discrimination at the cortical level. Psychophysical and cortical responses concurred with model
predictions, revealing discrimination thresholds in the range of 8–15 ms randomization‑window
length. Our data suggest that specialized cortical areas are not necessary to impart psychophysical
resilience to temporal distortion in communication calls.

Abstract

The functional region of interest (fROI) approach has increasingly become a favored methodology in functional magnetic resonance imaging (fMRI) because it can circumvent inter-subject anatomical and functional variability, and thus increase the sensitivity and functional resolution of fMRI analyses. The standard fROI method requires human experts to meticulously examine and identify subject-specific fROIs within activation clusters. This process is time-consuming and heavily dependent on experts’ knowledge. Several algorithmic approaches have been proposed for identifying subject-specific fROIs; however, these approaches cannot easily incorporate prior knowledge of inter-subject variability. In the present study, we improved the multi-atlas labeling approach for defining subject-specific fROIs. In particular, we used a classifier-based atlas-encoding scheme and an atlas selection procedure to account for the large spatial variability across subjects. Using a functional atlas database for face recognition, we showed that with these two features, our approach efficiently circumvented inter-subject anatomical and functional variability and thus improved labeling accuracy. Moreover, in comparison with a single-atlas approach, our multi-atlas labeling approach showed better performance in identifying subject-specific fROIs.

Abstract

Native speakers of Dutch do not always adhere to prescriptive grammar rules in their daily speech. These grammatical norm violations can elicit emotional reactions in language purists, mostly high-educated people, who claim that for them these constructions are truly ungrammatical. However, linguists generally assume that grammatical norm violations are in fact truly grammatical, especially when they occur frequently in a language. In an fMRI study we investigated the processing of grammatical norm violations in the brains of language purists, and compared them with truly grammatical and truly ungrammatical sentences. Grammatical norm violations were found to be unique in that their processing resembled not only the processing of truly grammatical sentences (in left medial Superior Frontal Gyrus and Angular Gyrus), but also that of truly ungrammatical sentences (in Inferior Frontal Gyrus), despite what theories of grammar would usually lead us to believe

Abstract

It is now well established that anticipation of up-coming input is a key characteristic of spoken language comprehension. Several mechanisms of predictive language processing have been proposed. The possible influence of mediating factors such as working memory and processing speed however has hardly been explored. We sought to find evidence for such an influence using an individual differences approach. 105 participants from 32 to 77 years of age received spoken instructions (e.g., "Kijk naar deCOM afgebeelde pianoCOM" - look at the displayed piano) while viewing four objects. Articles (Dutch “het” or “de”) were gender-marked such that the article agreed in gender only with the target. Participants could thus use gender information from the article to predict the upcoming target object. The average participant anticipated the target objects well in advance of the critical noun. Multiple regression analyses showed that working memory and processing speed had the largest mediating effects: Enhanced working memory abilities and faster processing speed supported anticipatory spoken language processing. These findings suggest that models of predictive language processing must take mediating factors such as working memory and processing speed into account. More generally, our results are consistent with the notion that working memory grounds language in space and time, linking linguistic and visual-spatial representations.

Abstract

Many psycholinguistic experiments suggest that prediction is an important characteristic of language processing. Some recent theoretical accounts in the cognitive sciences (e.g., Clark, 2013; Friston, 2010) and psycholinguistics (e.g., Dell & Chang, 2014) appear to suggest that prediction is even necessary to understand language. In the present opinion paper we evaluate this proposal. We first critically discuss several arguments that may appear to be in line with the notion that prediction is necessary for language processing. These arguments include that prediction provides a unified theoretical principle of the human mind and that it pervades cortical function. We discuss whether evidence of human abilities to detect statistical regularities is necessarily evidence for predictive processing and evaluate suggestions that prediction is necessary for language learning. Five arguments are then presented that question the claim that all language processing is predictive in nature. We point out that not all language users appear to predict language and that suboptimal input makes prediction often very challenging. Prediction, moreover, is strongly context-dependent and impeded by resource limitations. We also argue that it may be problematic that most experimental evidence for predictive language processing comes from 'prediction-encouraging' experimental set-ups. Finally, we discuss possible ways that may lead to a further resolution of this debate. We conclude that languages can be learned and understood in the absence of prediction. Claims that all language processing is predictive in nature are premature.

Abstract

We examined whether assortative mating for educational attainment (“like marries like”) can be detected in the genomes of ~ 1600 UK spouse pairs of European descent. Assortative mating on heritable traits like educational attainment increases the genetic variance and heritability of the trait in the population, which may increase social inequalities. We test for genetic assortative mating in the UK on educational attainment, a phenotype that is indicative of socio-economic status and has shown substantial levels of assortative mating. We use genome-wide allelic effect sizes from a large genome-wide association study on educational attainment (N ~ 300 k) to create polygenic scores that are predictive of educational attainment in our independent sample (r = 0.23, p < 2 × 10− 16). The polygenic scores significantly predict partners' educational outcome (r = 0.14, p = 4 × 10− 8 and r = 0.19, p = 2 × 10− 14, for prediction from males to females and vice versa, respectively), and are themselves significantly correlated between spouses (r = 0.11, p = 7 × 10− 6). Our findings provide molecular genetic evidence for genetic assortative mating on education in the UK

Abstract

The human body is central to myriad metaphors, so studying the conceptualisation of the body itself is critical if we are to understand its broader use. One essential but understudied issue is whether languages differ in which body parts they single out for naming. This paper takes a multi-method approach to investigate body part nomenclature within a single language family. Using both a naming task (Study 1) and colouring-in task (Study 2) to collect data from six Japonic languages, we found that lexical similarity for body part terminology was notably differentiated within Japonic, and similar variation was evident in semantics too. Novel application of cluster analysis on naming data revealed a relatively flat hierarchical structure for parts of the face, whereas parts of the body were organised with deeper hierarchical structure. The colouring data revealed that bounded parts show more stability across languages than unbounded parts. Overall, the data reveal there is not a single universal conceptualisation of the body as is often assumed, and that in-depth, multi-method explorations of under-studied languages are urgently required.

Abstract

Recent behavioural research has reported age-related changes in the costs of refocusing attention from a temporal (rapid serial visual presentation) to a spatial (visual search) task. Using magnetoencephalography, we have now compared the neural signatures of attention refocusing between three age groups (19–30, 40–49 and 60+ years) and found differences in task-related modulation and cortical localisation of alpha and theta oscillations. Efficient, faster refocusing in the youngest group compared to both middle age and older groups was reflected in parietal theta effects that were significantly reduced in the older groups. Residual parietal theta activity in older individuals was beneficial to attentional refocusing and could reflect preserved attention mechanisms. Slowed refocusing of attention, especially when a target required consolidation, in the older and middle-aged adults was accompanied by a posterior theta deficit and increased recruitment of frontal (middle-aged and older groups) and temporal (older group only) areas, demonstrating a posterior to anterior processing shift. Theta but not alpha modulation correlated with task performance, suggesting that older adults' stronger and more widely distributed alpha power modulation could reflect decreased neural precision or dedifferentiation but requires further investigation. Our results demonstrate that older adults present with different alpha and theta oscillatory signatures during attentional control, reflecting cognitive decline and, potentially, also different cognitive strategies in an attempt to compensate for decline.

Abstract

-* indicates joint senior authors - Parkinson’s disease impairs motor function and cognition, which together affect language and
communication. Co-speech gestures are a form of language-related actions that provide imagistic
depictions of the speech content they accompany. Gestures rely on visual and motor imagery, but
it is unknown whether gesture representations require the involvement of intact neural sensory
and motor systems. We tested this hypothesis with a fine-grained analysis of co-speech action
gestures in Parkinson’s disease. 37 people with Parkinson’s disease and 33 controls described
two scenes featuring actions which varied in their inherent degree of bodily motion. In addition
to the perspective of action gestures (gestural viewpoint/first- vs. third-person perspective), we
analysed how Parkinson’s patients represent manner (how something/someone moves) and path
information (where something/someone moves to) in gesture, depending on the degree of bodily
motion involved in the action depicted. We replicated an earlier finding that people with
Parkinson’s disease are less likely to gesture about actions from a first-person perspective – preferring instead to depict actions gesturally from a third-person perspective – and show that
this effect is modulated by the degree of bodily motion in the actions being depicted. When
describing high motion actions, the Parkinson’s group were specifically impaired in depicting
manner information in gesture and their use of third-person path-only gestures was significantly
increased. Gestures about low motion actions were relatively spared. These results inform our
understanding of the neural and cognitive basis of gesture production by providing
neuropsychological evidence that action gesture production relies on intact motor network
function.

Abstract

A combination of impaired motor and cognitive function in Parkinson’s disease (PD) can impact on language and communication, with patients exhibiting a particular difficulty processing action verbs. Co-speech gestures embody a link between action and language and contribute significantly to communication in healthy people. Here, we investigated how co-speech gestures depicting actions are affected in PD, in particular with respect to the visual perspective—or the viewpoint – they depict. Gestures are closely related to mental imagery and motor simulations, but people with PD may be impaired in the way they simulate actions from a first-person perspective and may compensate for this by relying more on third-person visual features. We analysed the action-depicting gestures produced by mild-moderate PD patients and age-matched controls on an action description task and examined the relationship between gesture viewpoint, action naming, and performance on an action observation task (weight judgement). Healthy controls produced the majority of their action gestures from a first-person perspective, whereas PD patients produced a greater proportion of gestures produced from a third-person perspective. We propose that this reflects a compensatory reliance on third-person visual features in the simulation of actions in PD. Performance was also impaired in action naming and weight judgement, although this was unrelated to gesture viewpoint. Our findings provide a more comprehensive understanding of how action-language impairments in PD impact on action communication, on the cognitive underpinnings of this impairment, as well as elucidating the role of action simulation in gesture production

Abstract

Retrieval from semantic memory of conceptual and lexical information is essential for producing speech. It is unclear whether there are differences in the neural mechanisms of conceptual and lexical retrieval when spreading activation through semantic memory is initiated by verbal or nonverbal settings. The same twenty participants took part in two EEG experiments. The first experiment examined conceptual and lexical retrieval following nonverbal settings, whereas the second experiment was a replication of previous studies examining conceptual and lexical retrieval following verbal settings. Target pictures were presented after constraining and nonconstraining contexts. In the nonverbal settings, contexts were provided as two priming pictures (e.g., constraining: nest, feather; nonconstraining: anchor, lipstick; target picture: BIRD). In the verbal settings, contexts were provided as sentences (e.g., constraining: “The farmer milked a...”; nonconstraining: “The child drew a...”; target picture: COW). Target pictures were named faster following constraining contexts in both experiments, indicating that conceptual preparation starts before target picture onset in constraining conditions. In the verbal experiment, we replicated the alpha-beta power decreases in constraining relative to nonconstraining conditions before target picture onset. No such power decreases were found in the nonverbal experiment. Power decreases in constraining relative to nonconstraining conditions were significantly different between experiments. Our findings suggest that participants engage in conceptual preparation following verbal and nonverbal settings, albeit differently. The retrieval of a target word, initiated by verbal settings, is associated with alpha-beta power decreases. By contrast, broad conceptual preparation alone, prompted by nonverbal settings, does not seem enough to elicit alpha-beta power decreases. These findings have implications for theories of oscillations and semantic memory.

Abstract

This paper examines how gesturers and signers use their bodies to express concepts such as instrumentality and humanness. Comparing across eight sign languages (American, Japanese, German, Israeli, and Kenyan Sign Languages, Ha Noi Sign Language of Vietnam, Central Taurus Sign Language of Turkey, and Al-Sayyid Bedouin Sign Language of Israel) and the gestures of American non-signers, we find recurring patterns for naming entities in three semantic categories (tools, animals, and fruits & vegetables). These recurring patterns are captured in a classification system that identifies iconic strategies based on how the body is used together with the hands. Across all groups, tools are named with manipulation forms, where the head and torso represent those of a human agent. Animals tend to be identified with personification forms, where the body serves as a map for a comparable non-human body. Fruits & vegetables tend to be identified with object forms, where the hands act independently from the rest of the body to represent static features of the referent. We argue that these iconic patterns are rooted in using the body for communication, and provide a basis for understanding how meaningful communication emerges quickly in gesture and persists in emergent and established sign languages.

Abstract

Foreign languages are often learned in emotionally neutral academic environments which differ greatly from the familiar context where native languages are acquired. This difference in learning contexts has been argued to lead to reduced emotional resonance when confronted with a foreign language. In the current study, we investigated whether the reactivity of the sympathetic nervous system in response to emotionally-charged stimuli is reduced in a foreign language. To this end, pupil sizes were recorded while reading aloud emotional sentences in the native or foreign language. Additionally, subjective ratings of emotional impact were provided after reading each sentence, allowing us to further investigate foreign language effects on explicit emotional understanding. Pupillary responses showed a larger effect of emotion in the native than in the foreign language. However, such a difference was not present for explicit ratings of emotionality. These results reveal that the sympathetic nervous system reacts differently depending on the language context, which in turns suggests a deeper emotional processing when reading in a native compared to a foreign language.

Abstract

Background Peripartum depression is a common cause of pregnancy- and postpartum-related morbidity. The production of corticotropin-releasing hormone (CRH) from the placenta alters the profile of hypothalamus–pituitary–adrenal axis hormones and may be associated with postpartum depression. The purpose of this study was to assess, in nondepressed pregnant women, the possible association between CRH levels in pregnancy and depressive symptoms postpartum. Methods A questionnaire containing demographic data and the Edinburgh Postnatal Depression Scale (EPDS) was filled in gestational weeks 17 and 32, and 6 week postpartum. Blood samples were collected in week 17 for assessment of CRH. A logistic regression model was constructed, using postpartum EPDS score as the dependent variable and log-transformed CRH levels as the independent variable. Confounding factors were included in the model. Subanalyses after exclusion of study subjects with preterm birth, newborns small for gestational age (SGA), and women on corticosteroids were performed. Results Five hundred thirty-five women without depressive symptoms during pregnancy were included. Logistic regression showed an association between high CRH levels in gestational week 17 and postpartum depressive symptoms, before and after controlling for several confounders (unadjusted OR = 1.11, 95% CI 1.01–1.22; adjusted OR = 1.13, 95% CI 1.02–1.26; per 0.1 unit increase in log CRH). Exclusion of women with preterm birth and newborns SGA as well as women who used inhalation corticosteroids during pregnancy did not alter the results. Conclusions This study suggests an association between high CRH levels in gestational week 17 and the development of postpartum depressive symptoms, among women without depressive symptoms during pregnancy.

Abstract

Background The human white matter pathway network is complex and of critical importance for functionality. Thus, learning
and understanding white matter tract anatomy is important for the training of neuroscientists and neurosurgeons. The study aims
to test and evaluate a new method for fiber dissection using augmented reality (AR) in a group which is experienced in cadaver
white matter dissection courses and in vivo tractography.
Methods Fifteen neurosurgeons, neurolinguists, and neuroscientists participated in this questionnaire-based study. We presented
five cases of patients with left-sided perisylvian gliomas who underwent awake craniotomy. Diffusion tensor imaging fiber
tracking (DTI FT) was performed and the language-related networks were visualized separated in different tracts by color.
Participants were able to virtually dissect the prepared DTI FTs using a spatial computer and AR goggles. The application
was evaluated through a questionnaire with answers from 0 (minimum) to 10 (maximum).
Results Participants rated the overall experience of AR fiber dissection with a median of 8 points (mean ± standard deviation 8.5 ± 1.4).
Usefulness for fiber dissection courses and education in general was rated with 8 (8.3 ± 1.4) and 8 (8.1 ± 1.5) points, respectively.
Educational value was expected to be high for several target audiences (student: median 9, 8.6 ± 1.4; resident: 9, 8.5 ± 1.8; surgeon: 9,
8.2 ± 2.4; scientist: 8.5, 8.0 ± 2.4). Even clinical application of AR fiber dissection was expected to be of value with a median of 7
points (7.0 ± 2.5)

Abstract

This paper presents the results of a comprehensive meta-analysis of the relevant imaging literature on word production (82 experiments). In addition to the spatial overlap of activated regions, we also analyzed the available data on the time course of activations. The analysis specified regions and time windows of activation for the core processes of word production: lexical selection, phonological code retrieval, syllabification, and phonetic/articulatory preparation. A comparison of the word production results with studies on auditory word/non-word perception and reading showed that the time course of activations in word production is, on the whole, compatible with the temporal constraints that perception processes impose on the production processes they affect in picture/word interference paradigms.

Abstract

Following up on an earlier positron emission tomography (PET) experiment (Indefrey et al., 2001), we used a scene description paradigm to investigate whether a posterior inferior frontal region subserving syntactic encoding for speaking is also involved in syntactic parsing during listening. In the language production part of the experiment, subjects described visually presented scenes
using either sentences, sequences of noun phrases, or sequences of syntactically unrelated words. In the language comprehension part of the experiment, subjects were auditorily presented with the same kinds of utterances and judged whether they matched the visual scenes. We were able to replicate the previous finding of a region in caudal Broca s area that is sensitive to the complexity of
syntactic encoding in language production. In language comprehension, no hemodynamic activation differences due to syntactic complexity were found. Given that correct performance in the judgment task did not require syntactic processing of the auditory stimuli, the results suggest that the degree to which listeners recruit syntactic processing resources in language comprehension may be a function of the syntactic demands of the task or the stimulus material.

Abstract

We investigated how two groups of Turkish-Dutch bilinguals and two groups of monolingual speakers of the two languages described static topological relations. The bilingual groups differed with respect to their first (L1) and second (L2) language proficiencies and a number of sociolinguistic factors. Using an elicitation tool that covers a wide range of topological relations, we first assessed the extensions of different spatial expressions (topological relation markers, TRMs) in the Turkish and Dutch spoken by monolingual speakers. We then assessed differences in the use of TRMs between the two bilingual groups and monolingual speakers. In both bilingual groups, differences compared to monolingual speakers were mainly observed for Turkish. Dutch-dominant bilinguals showed enhanced congruence between translation-equivalent Turkish and Dutch TRMs. Turkish-dominant bilinguals extended the use of a topologically neutral locative marker. Our results can be interpreted as showing different bilingual optimization strategies (Muysken, 2013) in bilingual speakers who live in the same environment but differ with respect to L2 onset, L2 proficiency, and perceived importance of the L1.

Abstract

In order to separate the cognitive processes associated with phonological encoding and the use of a visual word form lexicon in reading, it is desirable to compare the processing of words presented in a visually familiar form with words in a visually unfamiliar form. Japanese Kana orthography offers this possibility. Two phonologically equivalent but visually dissimilar syllabaries allow the writing of, for example, foreign loanwords in two ways, only one of which is visually familiar. Familiarly written words, unfamiliarly written words, and pseudowords were presented in both Kana syllabaries (yielding six conditions in total) to participants during an fMRI measurement with a silent articulation task (Experiment 1) and a phonological lexical decision task (Experiment 2) using an event-related design. Consistent over two experimental tasks, the three different stimulus types (familiar, unfamiliar, and pseudoword) were found to activate selectively different brain regions previously associated with phonological encoding and word retrieval or meaning. Compatible with the predictions of the dual-route model for reading, pseudowords and visually unfamiliar words, which have to be read using phonological assembly, caused an increase in brain activity in left inferior frontal regions (BA 44/47), as compared to visually familiar words. Visually familiar and unfamiliar words were found to activate a range of areas associated with lexico-semantic processing more strongly than pseudowords, such as the left and right temporo-parietal region (BA 39/40), a region in the left middle/inferior temporal gyrus (BA 20/21), and the posterior cingulate (BA 31).

Abstract

Current psycholinguistic theory proffers prediction as a central, explanatory mechanism in language
processing. However, widely-replicated prediction effects may not mean that prediction is
necessary in language processing. As a case in point, C. D. Martin et al. [2013. Bilinguals reading
in their second language do not predict upcoming words as native readers do.
Journal of
Memory and Language, 69
(4), 574
–
588. doi:10.1016/j.jml.2013.08.001] reported ERP evidence for
prediction in native- but not in non-native speakers. Articles mismatching an expected noun
elicited larger negativity in the N400 time window compared to articles matching the expected
noun in native speakers only. We attempted to replicate these findings, but found no evidence
for prediction irrespective of language nativeness. We argue that pre-activation of phonological
form of upcoming nouns, as evidenced in article-elicited effects, may not be a robust
phenomenon. A view of prediction as a necessary computation in language comprehension
must be re-evaluated.

Abstract

We used event-related potentials (ERP) to investigate whether Spanish−English bilinguals preactivate form and meaning of predictable words. Participants read high-cloze sentence contexts (e.g., “The student is going to the library to borrow a . . .”), followed by the predictable word (book), a word that was form-related (hook) or semantically related (page) to the predictable word, or an unrelated word (sofa). Word stimulus onset synchrony (SOA) was 500 ms (Experiment 1) or 700 ms (Experiment 2). In both experiments, all nonpredictable words elicited classic N400 effects. Form-related and unrelated words elicited similar N400 effects. Semantically related words elicited smaller N400s than unrelated words, which however, did not depend on cloze value of the predictable word. Thus, we found no N400 evidence for preactivation of form or meaning at either SOA, unlike native-speaker results (Ito, Corley et al., 2016). However, non-native speakers did show the post-N400 posterior positivity (LPC effect) for form-related words like native speakers, but only at the slower SOA. This LPC effect increased gradually with cloze value of the predictable word. We do not interpret this effect as necessarily demonstrating prediction, but rather as evincing combined effects of top-down activation (contextual meaning) and bottom-up activation (form similarity) that result in activation of unseen words that fit the context well, thereby leading to an interpretation conflict reflected in the LPC. Although there was no evidence that non-native speakers preactivate form or meaning, non-native speakers nonetheless appear to use bottom-up and top-down information to constrain incremental interpretation much like native speakers do.

Abstract

We used ERPs to investigate the pre-activation of form and meaning in language comprehension. Participants read high-cloze sentence contexts (e.g., “The student is going to the library to borrow a…”), followed by a word that was predictable (book), form-related (hook) or semantically related (page) to the predictable word, or unrelated (sofa). At a 500 ms SOA (Experiment 1), semantically related words, but not form-related words, elicited a reduced N400 compared to unrelated words. At a 700 ms SOA (Experiment 2), semantically related words and form-related words elicited reduced N400 effects, but the effect for form-related words occurred in very high-cloze sentences only. At both SOAs, form-related words elicited an enhanced, post-N400 posterior positivity (Late Positive Component effect). The N400 effects suggest that readers can pre-activate meaning and form information for highly predictable words, but form pre-activation is more limited than meaning pre-activation. The post-N400 LPC effect suggests that participants detected the form similarity between expected and encountered input. Pre-activation of word forms crucially depends upon the time that readers have to make predictions, in line with production-based accounts of linguistic prediction.

Abstract

Little research has been done on the effect of learning context on L2 listening development. Motivated by DeKeyser’s (2015) skill acquisition theory of second language acquisition, this study compares L2 listening development in study abroad (SA) and at home (AH) contexts from both language knowledge and processing perspectives. One hundred forty-nine Chinese postgraduates studying in either China or the United Kingdom participated in a battery of listening tasks at the beginning and at the end of an academic year. These tasks measure auditory vocabulary knowledge and listening processing efficiency (i.e., accuracy, speed, and stability of processing) in word recognition, grammatical processing, and semantic analysis. Results show that, provided equal starting levels, the SA learners made more progress than the AH learners in speed of processing across the language processing tasks, with less clear results for vocabulary acquisition. Studying abroad may be an effective intervention for L2 learning, especially in terms of processing speed.

Abstract

Little research has been done on the effect of learning context on L2 listening development. Motivated by DeKeyser’s (2015) skill acquisition theory of second language acquisition, this study compares L2 listening development in study abroad (SA) and at home (AH) contexts from both language knowledge and processing perspectives. One hundred forty-nine Chinese postgraduates studying in either China or the United Kingdom participated in a battery of listening tasks at the beginning and at the end of an academic year. These tasks measure auditory vocabulary knowledge and listening processing efficiency (i.e., accuracy, speed, and stability of processing) in word recognition, grammatical processing, and semantic analysis. Results show that, provided equal starting levels, the SA learners made more progress than the AH learners in speed of processing across the language processing tasks, with less clear results for vocabulary acquisition. Studying abroad may be an effective intervention for L2 learning, especially in terms of processing speed.

Abstract

Previous literature has identified several cognitive abilities as predictors of individual differences in speech perception. Working memory was chief among them, but effects have also been found for processing speed. Most research has been conducted on speech in noise, but fast and unclear articulation also makes listening challenging, particularly for older listeners. As a first step toward specifying the cognitive mechanisms underlying spoken word recognition, we set up this study to determine which factors explain unique variation in word identification accuracy in fast speech, and the extent to which this was affected by further degradation of the speech signal. To that end, 105 older adults were tested on identification accuracy of fast words in unaltered and degraded conditions in which the speech stimuli were low-pass filtered. They were also tested on processing speed, memory, vocabulary knowledge, and hearing sensitivity. A structural equation analysis showed that only memory and hearing sensitivity explained unique variance in word recognition in both listening conditions. Working memory was more strongly associated with performance in the unfiltered than in the filtered condition. These results suggest that memory skills, rather than speed, facilitate the mapping of single words onto stored lexical representations, particularly in conditions of medium difficulty.

Abstract

Natural fast speech differs from normal-rate speech with respect to its temporal pattern. Previous results showed that word intelligibility of heavily artificially time-compressed speech could not be improved by making its temporal pattern more similar to that of natural fast speech. This might have been due to the extrapolation of timing rules for natural fast speech to rates that are much faster than can be attained by human speakers. The present study investigates whether, at a speech rate that human speakers can attain, artificially time-compressed speech is easier to process if its timing pattern is similar to that of naturally produced fast speech. Our first experiment suggests, however, that word processing speed was slowed down, relative to linear compression. In a second experiment, word processing of artificially time-compressed speech was compared with processing of naturally produced fast speech. Even when naturally produced fast speech is perfectly intelligible, its less careful articulation, combined with the changed timing pattern, slows down processing, relative to linearly time-compressed speech. Furthermore, listeners preferred artificially time-compressed speech over naturally produced fast speech. These results suggest that linearly time-compressed speech has both a temporal and a segmental advantage over natural fast speech.

Abstract

SETBP1 haploinsufficiency disorder (MIM#616078) is caused by haploinsufficiency of SETBP1 on chromosome 18q12.3, but there has not yet been any systematic evaluation of the major features of this monogenic syndrome, assessing penetrance and expressivity. We describe the first comprehensive study to delineate the associated clinical phenotype, with findings from 34 individuals, including 24 novel cases, all of whom have a SETBP1 loss-of-function variant or single (coding) gene deletion, confirmed by molecular diagnostics. The most commonly reported clinical features included mild motor developmental delay, speech impairment, intellectual disability, hypotonia, vision impairment, attention/concentration deficits, and hyperactivity. Although there is a mild overlap in certain facial features, the disorder does not lead to a distinctive recognizable facial gestalt. As well as providing insight into the clinical spectrum of SETBP1 haploinsufficiency disorder, this reports puts forward care recommendations for patient management.

Abstract

This study investigated the encoding of syllable boundary information during speech production in Dutch. Based on Levelt's model of phonological encoding, we hypothesized segments and syllable boundaries to be encoded in an incremental way. In a selfmonitoring experiment, decisions about the syllable affiliation (first or second syllable) of a pre-specified consonant, which was the third phoneme in a word, were required (e.g., ka.No canoe vs. kaN.sel pulpit ; capital letters indicate pivotal consonants, dots mark syllable boundaries). First syllable responses were faster than second syllable responses, indicating the incremental nature of segmental encoding and syllabification during speech production planning. The results of the experiment are discussed in the context of Levelt 's model of phonological encoding.

Abstract

Three experiments are reported that examined whether stem complexity plays a role in inflecting polymorphemic words in language production. Experiment 1 showed that preparation effects for words with polymorphemic stems are larger when they are produced among words with constant inflectional structures compared to words with variable inflectional structures and simple stems. This replicates earlier findings for words with monomorphemic stems (Janssen et al., 2002). Experiments 2 and 3 showed that when inflectional structure is held constant, the preparation effects are equally large with simple and compound stems, and with compound and complex adjectival stems. These results indicate that inflectional encoding is blind to the complexity of the stem, which suggests that specific inflectional rather than generic morphological frames guide the generation of inflected forms in speaking words.

Abstract

Coevolving systems are notoriously difficult to understand. This is largely due to the Red Queen effect that dictates heterospecific fitness interdependence. In simulation studies of coevolving systems, master tournaments are often used to obtain more informed fitness measures by testing evolved individuals against past and future opponents. However, such tournaments still contain certain ambiguities. We introduce the use of a phenotypic cluster analysis to examine the distribution of opponent categories throughout an evolutionary sequence. This analysis, adopted from widespread usage in the bioinformatics community, can be applied to master tournament data. This allows us to construct behavior-based category trees, obtaining a hierarchical classification of phenotypes that are suspected to interleave during cyclic evolution. We use the cluster data to establish the existence of switching-genes that control opponent specialization, suggesting the retention of dormant genetic adaptations, that is, genetic memory. Our overarching goal is to reiterate how computer simulations may have importance to the broader understanding of evolutionary dynamics in general. We emphasize a further shift from a component-driven to an interaction-driven perspective in understanding coevolving systems. As yet, it is unclear how the sudden development of switching-genes relates to the gradual emergence of genetic adaptability. Likely, context genes gradually provide the appropriate genetic environment wherein the switching-gene effect can be exploited

Abstract

Schizophrenia is a biologically complex disorder with multiple regional deficits in cortical brain morphology. In addition, interindividual heterogeneity of cortical morphological metrics is larger in patients with schizophrenia when compared to healthy controls. Exploiting interindividual differences in the severity of cortical morphological deficits in patients instead of focusing on group averages may aid in detecting biologically informed homogeneous subgroups. The person-based similarity index (PBSI) of brain morphology indexes an individual’s morphometric similarity across numerous cortical regions amongst a sample of healthy subjects. We extended the PBSI such that it indexes the morphometric similarity of an independent individual (eg, a patient) with respect to healthy control subjects. By employing a normative modeling approach on longitudinal data, we determined an individual’s degree of morphometric dissimilarity to the norm. We calculated the PBSI for sulcal width (PBSI-SW) in patients with schizophrenia and healthy control subjects (164 patients and 164 healthy controls; 656 magnetic resonance imaging scans) and associated it with cognitive performance and cortical sulcation index. A subgroup of patients with markedly deviant PBSI-SW showed extreme deficits in cognitive performance and cortical sulcation. Progressive reduction of PBSI-SW in the schizophrenia group relative to healthy controls was driven by these deviating individuals. By explicitly leveraging interindividual differences in the severity of PBSI-SW deficits, neuroimaging-driven subgrouping of patients is feasible. As such, our results pave the way for future applications of morphometric similarity indices for subtyping of clinical populations.

Abstract

Children's abilities to process the phonological structure of words are important predictors of their literacy development. In the current study, we examined the interrelatedness between implicit (i.e., speech decoding) and explicit (i.e., phonological awareness) phonological abilities, and especially the role therein of lexical specificity (i.e., the ability to learn to recognize spoken words based on only minimal acoustic-phonetic differences). We tested 75 Dutch monolingual and 64 Turkish–Dutch bilingual kindergartners. SEM analyses showed that speech decoding predicted lexical specificity, which in turn predicted rhyme awareness in the first language learners but phoneme awareness in the second language learners. Moreover, in the latter group there was an impact of the second language: Dutch speech decoding and lexical specificity predicted Turkish phonological awareness, which in turn predicted Dutch phonological awareness. We conclude that language-specific phonological characteristics underlie different patterns of transfer from implicit to explicit phonological abilities in first and second language learners.

Abstract

As people find their way through their environment, objects at navigationally relevant locations can serve as crucial landmarks. The parahippocampal gyrus has previously been shown to be involved in object and scene recognition. In the present study, we investigated the neural representation of navigationally relevant locations. Healthy human adults viewed a route through a virtual museum with objects placed at intersections (decision points) or at simple turns (non-decision points). Event-related functional magnetic resonance imaging (fMRI) data were acquired during subsequent recognition of the objects in isolation. Neural activity in the parahippocampal gyrus reflected the navigational relevance of an object's location in the museum. Parahippocampal responses were selectively increased for objects that occurred at decision points, independent of attentional demands. This increase occurred for forgotten as well as remembered objects, showing implicit retrieval of navigational information. The automatic storage of relevant object location in the parahippocampal gyrus provides a part of the neural mechanism underlying successful navigation.

Abstract

Human social intelligence relies on our ability to infer other people’s mental states such as their beliefs, desires,and intentions. While people are proficient at mental state inference from physical action, it is unknown whether people can make inferences of comparable granularity from simple linguistic events. Here, we show that people can make quantitative mental state attributions from simple referential expressions, replicating the fine-grained inferential structure characteristic of nonlinguistic theory of mind. Moreover, people quantitatively adjust these inferences after brief exposures to speaker-specific speech patterns. These judgments matched the predictions made by our computational model of theory of mind in language, but could not be explained by a simpler qualitative model that attributes mental states deductively. Our findings show how the connection between language and theory of mind runs deep, with their interaction showing in one of the most fundamental forms of human communication: reference.

Abstract

The present study describes how three now almost forgotten mid-20th-century logicians, the American Paul Jacoby and the Frenchmen Augustin Sesmat and Robert Blanché, all three ardent Catholics, tried to restore traditional predicate logic to a position of respectability by expanding the classic Square of Opposition to a hexagon of logical relations, showing the logical and cognitive advantages of such an expansion. The nature of these advantages is discussed in the context of modern research regarding the relations between logic, language, and cognition. It is desirable to call attention to these attempts, as they are, though almost totally forgotten, highly relevant against the backdrop of the clash between modern and traditional logic. It is argued that this clash was and is unnecessary, as both forms of predicate logic are legitimate, each in its own right. The attempts by Jacoby, Sesmat, and Blanché are, moreover, of interest to the history of logic in a cultural context in that, in their own idiosyncratic ways, they fit into the general pattern of the Catholic cultural revival that took place roughly between the years 1840 and 1960. The Catholic Church had put up stiff resistance to modern mathematical logic, considering it dehumanizing and a threat to Catholic doctrine. Both the wider cultural context and the specific implications for logic are described and analyzed, in conjunction with the more general philosophical and doctrinal issues involved.