Publications

Abstract

Objective Recently, de novo SCN8A missense mutations have been identified as a rare dominant cause of epileptic encephalopathies. Functional studies on the first described case demonstrated gain-of-function effects of the mutation. We describe a novel de novo mutation of SCN8A in a patient with epileptic encephalopathy, and functional characterization of the mutant protein. Design Whole exome sequencing was used to discover the variant. We generated a mutant cDNA, transfected HEK293 cells, and performed Western blotting to assess protein stability. To study channel functional properties, patch-clamp experiments were carried out in transfected neuronal ND7/23 cells. Results The proband exhibited seizure onset at 6 months of age, diffuse brain atrophy, and more profound developmental impairment than the original case. The mutation p.Arg233Gly in the voltage sensing transmembrane segment D1S4 was present in the proband and absent in both parents. This mutation results in a temperature-sensitive reduction in protein expression as well as reduced sodium current amplitude and density and a relative increased response to a slow ramp stimulus, though this did not result in an absolute increased current at physiological temperatures. Conclusion The new de novo SCN8A mutation is clearly deleterious, resulting in an unstable protein with reduced channel activity. This differs from the gain-of-function attributes of the first SCN8A mutation in epileptic encephalopathy, pointing to heterogeneity of mechanisms. Since Nav1.6 is expressed in both excitatory and inhibitory neurons, a differential effect of a loss-of-function of Nav1.6 Arg223Gly on inhibitory interneurons may underlie the epilepsy phenotype in this patient.

Abstract

Hand preference is a conspicuous variation in human behaviour, with a worldwide proportion of around 90% of people preferring to use the right hand for many tasks, and 10% the left hand. We used the large cohort of the UK biobank (~500,000 participants) to study possible relations between early life factors and adult hand preference. The probability of being left-handed was affected by the year and location of birth, likely due to cultural effects. In addition, hand preference was affected by birthweight, being part of a multiple birth, season of birth, breastfeeding, and sex, with each effect remaining significant after accounting for all others. Analysis of genome-wide genotype data showed that left-handedness was very weakly heritable, but shared no genetic basis with birthweight. Although on average left-handers and right-handers differed for a number of early life factors, all together these factors had only a minimal predictive value for individual hand preference.

Abstract

Coronary Artery Disease (CAD) remains the leading cause of mortality worldwide. Mortality rates associated with CAD have shown an exceptional increase particularly in fast developing economies like the Kingdom of Saudi Arabia (KSA). Over the past twenty years, CAD has become the leading cause of death in KSA and has reached epidemic proportions. This rise is undoubtedly caused by fast urbanization that is associated with a life-style that promotes CAD. However, the question remains whether genetics play a significant role and whether genetic susceptibility is increased in KSA compared to the well-studied Western European populations. Therefore, we performed an Exome-wide association study (EWAS) in 832 patients and 1,076 controls of Saudi Arabian origin to test whether population specific, strong genetic risk factors for CAD exist, or whether the polygenic risk score for known genetic risk factors for CAD, lipids, and Type 2 Diabetes show evidence for an enriched genetic burden. Our results do not show significant associations for a single genetic locus. However, the heritability estimate for CAD for this population was high (h2 = 0.53, S.E. = 0.1, p = 4e-12) and we observed a significant association of the polygenic risk score for CAD that demonstrates that the population of KSA, at least in part, shares the genetic risk associated to CAD in Western populations.

Abstract

Objective:

Asymmetry is a subtle but pervasive aspect of the human brain, and it may be altered in several psychiatric conditions. MRI studies have shown subtle differences of brain anatomy between people with major depressive disorder and healthy control subjects, but few studies have specifically examined brain anatomical asymmetry in relation to this disorder, and results from those studies have remained inconclusive. At the functional level, some electroencephalography studies have indicated left fronto-cortical hypoactivity and right parietal hypoactivity in depressive disorders, so aspects of lateralized anatomy may also be affected. The authors used pooled individual-level data from data sets collected around the world to investigate differences in laterality in measures of cortical thickness, cortical surface area, and subcortical volume between individuals with major depression and healthy control subjects.
Methods:

The authors investigated differences in the laterality of thickness and surface area measures of 34 cerebral cortical regions in 2,256 individuals with major depression and 3,504 control subjects from 31 separate data sets, and they investigated volume asymmetries of eight subcortical structures in 2,540 individuals with major depression and 4,230 control subjects from 32 data sets. T1-weighted MRI data were processed with a single protocol using FreeSurfer and the Desikan-Killiany atlas. The large sample size provided 80% power to detect effects of the order of Cohen’s d=0.1.
Results:

The largest effect size (Cohen’s d) of major depression diagnosis was 0.085 for the thickness asymmetry of the superior temporal cortex, which was not significant after adjustment for multiple testing. Asymmetry measures were not significantly associated with medication use, acute compared with remitted status, first episode compared with recurrent status, or age at onset.
Conclusions:

Altered brain macro-anatomical asymmetry may be of little relevance to major depression etiology in most cases.

Abstract

Background Many genes are candidates for involvement in epileptic encephalopathy (EE) because one or a few possibly pathogenic variants have been found in patients, but insufficient genetic or functional evidence exists for a definite annotation. Methods To increase the number of validated EE genes, we sequenced 26 known and 351 candidate genes for EE in 360 patients. Variants in 25 genes known to be involved in EE or related phenotypes were followed up in 41 patients. We pri- oritized the candidate genes, and followed up 31 variants in this prioritized subset of candidate genes. Results Twenty-nine genotypes in known genes for EE (19) or related diseases (10), dominant as well as recessive or X-linked, were classified as likely pathogenic variants. Among those, likely pathogenic de novo variants were found in EE genes that act dominantly, including the recently identified genes EEF1A2, KCNB1 and the X-linked gene IQSEC2 .A de novo frameshift variant in candi- date gene HNRNPU was the only de novo variant found among the followed- up candidate genes, and the patient’s phenotype was similar to a few recent publication

Abstract

Hand preference is a prominent behavioural trait linked to human brain asymmetry. A handful of genetic variants have been reported to associate with hand preference or quantitative measures related to it. Most of these reports were on the basis of limited sample sizes, by current standards for genetic analysis of complex traits. Here we performed a genome-wide association analysis of hand preference in the large, population-based UK Biobank cohort (N = 331,037). We used gene-set enrichment analysis to investigate whether genes involved in visceral asymmetry are particularly relevant to hand preference, following one previous report. We found no evidence supporting any of the previously suggested variants or genes, nor that genes involved in visceral laterality have a role in hand preference. It remains possible that some of the previously reported genes or pathways are relevant to hand preference as assessed in other ways, or else are relevant within specific disorder populations. However, some or all of the earlier findings are likely to be false positives, and none of them appear relevant to hand preference as defined categorically in the general population. Our analysis did produce a small number of novel, significant associations, including one implicating the microtubule-associated gene MAP2 in handedness.

Abstract

Previous studies of Austrian Sign Language (ÖGS) word-order variations have demonstrated the human processing system’s tendency to interpret a sentence-initial (case-) ambiguous argument as the subject of the clause (“subject preference”). The electroencephalogram study motivating the current report revealed earlier reanalysis effects for object-subject compared to subject-object sentences, in particular, before the start of the movement of the agreement marking sign. The effects were bound to time points prior to when both arguments were referenced in space and/or the transitional hand movement prior to producing the disambiguating sign. Due to the temporal proximity of these time points, it was not clear which visual cues led to disambiguation; that is, whether non-manual markings (body/shoulder/head shift towards the subject position) or the transitional hand movement resolved ambiguity. The present gating study further supports that disambiguation in ÖGS is triggered by cues occurring before the movement of the disambiguating sign. Further, the present study also confirms the presence of the subject preference in ÖGS, showing again that signers and speakers draw on similar strategies during language processing independent of language modality. Although the ultimate role of the visual cues leading to disambiguation (i.e., non-manual markings and transitional movements) requires further investigation, the present study shows that they contribute crucial information about argument structure during online processing. This finding provides strong support for granting these cues some degree of linguistic status (at least in ÖGS).

Abstract

Counterfactual thought allows people to consider alternative worlds they know to be false. Communicating these thoughts through language poses a social-communicative challenge because listeners typically expect a speaker to produce true utterances, but counterfactuals per definition convey information that is false. Listeners must therefore incorporate overt linguistic cues (subjunctive mood, such as in If I loved you then) in a rapid way to infer the intended counterfactual meaning. The present EEG study focused on the comprehension of such counterfactual antecedents and investigated if pragmatic ability—the ability to apply knowledge of the social-communicative use of language in daily life—predicts the online generation of counterfactual worlds. This yielded two novel findings: (1) Words that are consistent with factual knowledge incur a semantic processing cost, as reflected in larger N400 amplitude, in counterfactual antecedents compared to hypothetical antecedents (If sweets were/are made of sugar). We take this to suggest that counterfactuality is quickly incorporated during language comprehension and reduces online expectations based on factual knowledge. (2) Individual scores on the Autism Quotient Communication subscale modulated this effect, suggesting that individuals who are better at understanding the communicative intentions of other people are more likely to reduce knowledge-based expectations in counterfactuals. These results are the first demonstration of the real-time pragmatic processes involved in creating possible worlds.

Abstract

Cognitive and linguistic theories of counterfactual language comprehension assume that counterfactuals convey a dual meaning. Subjunctive-counterfactual conditionals (e.g., ‘If Tom had studied hard, he would have passed the test’) express a supposition while implying the factual state of affairs (Tom has not studied hard and failed). The question of how counterfactual dual meaning plays out during language processing is currently gaining interest in psycholinguistics. Whereas numerous studies using offline measures of language processing consistently support counterfactual dual meaning, evidence coming from online studies is less conclusive. Here, we review the available studies that examine online counterfactual language comprehension through behavioural measurement (self-paced reading times, eye-tracking) and neuroimaging (electroencephalography, functional magnetic resonance imaging). While we argue that these studies do not offer direct evidence for the online computation of counterfactual dual meaning, they provide valuable information about the way counterfactual meaning unfolds in time and influences successive information processing. Further advances in research on counterfactual comprehension require more specific predictions about how counterfactual dual meaning impacts incremental sentence processing.

Abstract

The Profile of Music Perception Skills (PROMS) is a recently developed measure of perceptual music skills which has been shown to have promising psychometric properties. In this paper we extend the evaluation of its brief version to three kinds of validity using an individual difference approach. The brief PROMS displays good discriminant validity with working memory, given that it does not correlate with backward digit span (r = .04). Moreover, it shows promising criterion validity (association with musical training (r = .45), musicianship status (r = .48), and self-rated musical talent (r = .51)). Finally, its convergent validity, i.e. relation to an unrelated measure of music perception skills, was assessed by correlating the brief PROMS to harmonic closure judgment accuracy. Two independent samples point to good convergent validity of the brief PROMS (r = .36; r = .40). The same association is still significant in one of the samples when including self-reported music skill in a partial correlation (rpartial = .30; rpartial = .17). Overall, the results show that the brief version of the PROMS displays a very good pattern of construct validity. Especially its tuning subtest stands out as a valuable part for music skill evaluations in Western samples. We conclude by briefly discussing the choice faced by music cognition researchers between different musical aptitude measures of which the brief PROMS is a well evaluated example.

Abstract

Many studies have revealed shared music–language processing resources by finding an influence of music harmony manipulations on concurrent language processing. However, the nature of the shared resources has remained ambiguous. They have been argued to be syntax specific and thus due to shared syntactic integration resources. An alternative view regards them as related to general attention and, thus, not specific to syntax. The present experiments evaluated these accounts by investigating the influence of language on music. Participants were asked to provide closure judgements on harmonic sequences in order to assess the appropriateness of sequence endings. At the same time participants read syntactic garden-path sentences. Closure judgements revealed a change in harmonic processing as the result of reading a syntactically challenging word. We found no influence of an arithmetic control manipulation (experiment 1) or semantic garden-path sentences (experiment 2). Our results provide behavioural evidence for a specific influence of linguistic syntax processing on musical harmony judgements. A closer look reveals that the shared resources appear to be needed to hold a harmonic key online in some form of syntactic working memory or unification workspace related to the integration of chords and words. Overall, our results support the syntax specificity of shared music–language processing resources.

Abstract

Recently, many psychological effects have been surprisingly difficult to reproduce. This article asks why, and investigates whether conceptually replicating an effect in the original publication is related to the success of independent, direct replications. Two prominent accounts of low reproducibility make different predictions in this respect. One account suggests that psychological phenomena are dependent on unknown contexts that are not reproduced in independent replication attempts. By this account, internal replications indicate that a finding is more robust and, thus, that it is easier to independently replicate it. An alternative account suggests that researchers employ questionable research practices (QRPs), which increase false positive rates. By this account, the success of internal replications may just be the result of QRPs and, thus, internal replications are not predictive of independent replication success. The data of a large reproducibility project support the QRP account: replicating an effect in the original publication is not related to independent replication success. Additional analyses reveal that internally replicated and internally unreplicated effects are not very different in terms of variables associated with replication success. Moreover, social psychological effects in particular appear to lack any benefit from internal replications. Overall, these results indicate that, in this dataset at least, the influence of QRPs is at the heart of failures to replicate psychological findings, especially in social psychology. Variable, unknown contexts appear to play only a relatively minor role. I recommend practical solutions for how QRPs can be avoided.

Abstract

Developmental dyslexia is often characterized by a dual deficit in both word recognition accuracy and general processing speed. While previous research into dyslexic word recognition may have suffered from speed-accuracy trade-off, the present study employed a novel eye-tracking task that is less prone to such confounds. Participants (10 dyslexics and 12 controls) were asked to look at real word stimuli, and to ignore simultaneously presented non-word stimuli, while their eye-movements were recorded. Improvements in word recognition accuracy over time were modeled in terms of a continuous non-linear function. The words' rhyme consistency and the non-words' lexicality (unpronounceable, pronounceable, pseudohomophone) were manipulated within-subjects. Speed-related measures derived from the model fits confirmed generally slower processing in dyslexics, and showed a rhyme consistency effect in both dyslexics and controls. In terms of overall error rate, dyslexics (but not controls) performed less accurately on rhyme-inconsistent words, suggesting a representational deficit for such words in dyslexics. Interestingly, neither group showed a pseudohomophone effect in speed or accuracy, which might call the task-independent pervasiveness of this effect into question. The present results illustrate the importance of distinguishing between speed- vs. accuracy-related effects for our understanding of dyslexic word recognition

Abstract

It has been hypothesized that schizophrenia is characterized by overly broad automatic activity within lexico-semantic networks. We used two complementary neuroimaging techniques, Magnetoencephalography (MEG) and functional Magnetic Resonance Imaging (fMRI), in combination with a highly automatic indirect semantic priming paradigm, to spatiotemporally localize this abnormality in the brain.

Eighteen people with schizophrenia and 20 demographically-matched control participants viewed target words (“bell”) preceded by directly related (“church”), indirectly related (“priest”), or unrelated (“pants”) prime words in MEG and fMRI sessions. To minimize top-down processing, the prime was masked, the target appeared only 140ms after prime onset, and participants simply monitored for words within a particular semantic category that appeared in filler trials.

Both techniques revealed a significantly larger automatic indirect priming effect in people with schizophrenia than in control participants. MEG temporally localized this enhanced effect to the N400 time window (300-500ms) — the critical stage of accessing meaning from words. fMRI spatially localized the effect to the left temporal fusiform cortex, which plays a role in mapping of orthographic word-form on to meaning. There was no evidence of an enhanced automatic direct semantic priming effect in the schizophrenia group.

These findings provide converging neural evidence for abnormally broad highly automatic lexico-semantic activity in schizophrenia. We argue that, rather than arising from an unconstrained spread of automatic activation across semantic memory, this broader automatic lexico-semantic activity stems from looser connections between the form and meaning of words.

Abstract

This study investigates the adult grammars of French simultaneous bilingual speakers (2L1s) whose other language is German. Apart from providing an example of French as heritage language in Europe, the goals of this paper are (i) to compare the acquisition of French in a minority and majority language context, (ii) to identify the relative vulnerability of individual domains, and (iii) to investigate whether 2L1s are vulnerable to language attrition when moving to their heritage country during adulthood. We include two groups of German-French 2L1s: One group grew up predominantly in France, but moved to Germany during adulthood; the other group grew up predominantly in Germany and stayed there. Performance is compared in different domains, including adjective placement, gender marking, articles, prepositions, foreign accent and voice onset time. Results indicate that differences between the two groups are minimal in morpho-syntax, but more prominent in pronunciation.

Abstract

In spontaneous conversations between adults, words are often pronounced with fewer segments or syllables than their citation forms. The question arises whether infant-directed speech also contains phonetic reduction. If so, infants would be presented with speech input that enables them to acquire reduced variants from an early age. This study compared speech directed at 11- and 12-month-old infants with adult-directed conversational speech and adult-directed read speech. In an acoustic study, 216 tokens of the Dutch words allemaal and helemaal from speech corpora were analyzed for duration, number of syllables, and vowel quality. In a perception study, adult participants rated these same materials for reduction and provided phonetic transcriptions. The results show that these two words are frequently reduced in infant-directed speech, and that their degree of reduction is comparable with conversational adult-directed speech. These findings suggest that lexical representations for reduced pronunciation variants can be acquired early in linguistic development

Abstract

Research on prediction in language processing has focused predominantly on the function of predictive context and less on the potential contribution of the predicted word. The present study investigated how meaning that is not immediately prominent in the contents of predictions but is part of the predicted words influences sentence processing. We used emotional meaning to address this question. Participants read emotional and neutral words embedded in highly predictive and non-predictive sentential contexts, with the two sentential contexts rated similarly for their emotional ratings. Event Related Potential (ERP) effects of prediction and emotion both started at ~200 ms. Confirmed predictions elicited larger P200s than violated predictions when the target words were non-emotional (neutral), but such effect was absent when the target words were emotional. Likewise, emotional words elicited larger P200s than neutral words when the target words were non-predictive, but such effect were absent when the contexts were predictive. We conjecture that the prediction and emotion effects at ~200 ms may share similar neural process(es). We suggest that such process(es) could be affective, where confirmed predictions and word emotion give rise to ‘aha’ or reward feelings, and/or cognitive, where both prediction and word emotion quickly engage attention

Abstract

When speakers describe motion events using different languages, they subsequently classify those events in language-specific ways (Gennari, Sloman, Malt & Fitch, 2002). Here we ask if bilingual speakers flexibly shift their event classification preferences based on the language in which they verbally encode those events. English–Spanish bilinguals and monolingual controls described motion events in either Spanish or English. Subsequently they judged the similarity of the motion events in a triad task. Bilinguals tested in Spanish and Spanish monolinguals were more likely to make similarity judgments based on the path of motion versus bilinguals tested in English and English monolinguals. The effect is modulated in bilinguals by the age of acquisition of the second language. Late bilinguals based their judgments on path more often when Spanish was used to describe the motion events versus English. Early bilinguals had a path preference independent of the language in use. These findings support “thinking-for-speaking” (Slobin, 1996) in late bilinguals.

Abstract

We used magnetoencephalography (MEG) to explore the spatio-temporal dynamics of neural oscillations associated with sentence processing, in 102 participants. We quantified changes in oscillatory power as the sentence unfolded, and in response to individual words in the sentence. For words early in a sentence compared to those late in the same sentence, we observed differences in left temporal and frontal areas, and bilateral frontal and right parietal regions for the theta, alpha, and beta frequency bands. The neural response to words in a sentence differed from the response to words in scrambled sentences in left-lateralized theta, alpha, beta, and gamma. The theta band effects suggest that a sentential context facilitates lexical retrieval, and that this facilitation is stronger for words late in the sentence. Effects in the alpha and beta band may reflect the unification of semantic and syntactic information, and are suggestive of easier unification late in a sentence. The gamma oscillations are indicative of predicting the upcoming word during sentence processing. In conclusion, changes in oscillatory neuronal activity capture aspects of sentence processing. Our results support earlier claims that language (sentence) processing recruits areas distributed across both hemispheres, and extends beyond the classical language regions

Abstract

Dance is an icon of human expression. Despite astounding diversity around the world’s cultures and dazzling abundance of reminiscent animal systems, the evolution of dance in the human clade remains obscure. Dance requires individuals to interactively synchronize their whole-body tempo to their partner’s, with near-perfect precision. This capacity is motorically-heavy, engaging multiple neural circuitries, but also dependent on an acute socio-emotional bond between partners. Hitherto, these factors helped explain why no dance forms were present amongst nonhuman primates. Critically, evidence for conjoined full-body rhythmic entrainment in great apes that could help reconstruct possible proto-stages of human dance is still lacking. Here, we report an endogenously-effected case of ritualized dance-like behaviour between two captive chimpanzees – synchronized bipedalism. We submitted video recordings to rigorous time-series analysis and circular statistics. We found that individual step tempo was within the genus’ range of “solo” bipedalism. Between-individual analyses, however, revealed that synchronisation between individuals was non-random, predictable, phase concordant, maintained with instantaneous centi-second precision and jointly regulated, with individuals also taking turns as “pace-makers”. No function was apparent besides the behaviour’s putative positive social affiliation. Our analyses show a first case of spontaneous whole-body entrainment between two ape peers, thus providing tentative empirical evidence for phylogenies of human dance. Human proto-dance, we argue, may have been rooted in mechanisms of social cohesion among small groups that might have granted stress-releasing benefits via gait-synchrony and mutual-touch. An external sound/musical beat may have been initially uninvolved. We discuss dance evolution as driven by ecologically-, socially- and/or culturally-imposed “captivity”.

Abstract

Background Mutations in the KIAA2022 gene have been reported in male patients with X-linked intellectual disability, and related female carriers were unaffected. Here, we report 14 female patients who carry a heterozygous de novo KIAA2022 mutation and share a phenotype characterised by intellectual disability and epilepsy.

Methods Reported females were selected for genetic testing because of substantial developmental problems and/or epilepsy. X-inactivation and expression studies were performed when possible.

Results All mutations were predicted to result in a frameshift or premature stop. 12 out of 14 patients had intractable epilepsy with myoclonic and/or absence seizures, and generalised in 11. Thirteen patients had mild to severe intellectual disability. This female phenotype partially overlaps with the reported male phenotype which consists of more severe intellectual disability, microcephaly, growth retardation, facial dysmorphisms and, less frequently, epilepsy. One female patient showed completely skewed X-inactivation, complete absence of RNA expression in blood and a phenotype similar to male patients. In the six other tested patients, X-inactivation was random, confirmed by a non-significant twofold to threefold decrease of RNA expression in blood, consistent with the expected mosaicism between cells expressing mutant or normal KIAA2022 alleles.

Conclusions Heterozygous loss of KIAA2022 expression is a cause of intellectual disability in females. Compared with its hemizygous male counterpart, the heterozygous female disease has less severe intellectual disability, but is more often associated with a severe and intractable myoclonic epilepsy.

Abstract

We contrast two related hypotheses of the evolution of dance: H1: Maternal bipedal walking influenced the fetal experience of sound and associated movement patterns; H2: The human transition to bipedal gait produced more isochronous/predictable locomotion sound resulting in early music-like behavior associated with the acoustic advantages conferred by moving bipedally in pace. The cadence of walking is around 120 beats per minute, similar to the tempo of dance and music. Human walking displays long-term constancies. Dyads often subconsciously synchronize steps. The major amplitude component of the step is a distinctly produced beat. Human locomotion influences, and interacts with, emotions, and passive listening to music activates brain motor areas. Across dance-genres the footwork is most often performed in time to the musical beat. Brain development is largely shaped by early sensory experience, with hearing developed from week 18 of gestation. Newborns reacts to sounds, melodies, and rhythmic poems to which they have been exposed in utero. If the sound and vibrations produced by footfalls of a walking mother are transmitted to the fetus in coordination with the cadence of the motion, a connection between isochronous sound and rhythmical movement may be developed. Rhythmical sounds of the human mother locomotion differ substantially from that of nonhuman primates, while the maternal heartbeat heard is likely to have a similar isochronous character across primates, suggesting a relatively more influential role of footfall in the development of rhythmic/musical abilities in humans. Associations of gait, music, and dance are numerous. The apparent absence of musical and rhythmic abilities in nonhuman primates, which display little bipedal locomotion, corroborates that bipedal gait may be linked to the development of rhythmic abilities in humans. Bipedal stimuli in utero may primarily boost the ontogenetic development. The acoustical advantage hypothesis proposes a mechanism in the phylogenetic development.

Abstract

This study investigated processing of emotion words in autism spectrum disorders (ASD) using reaction times and event-related potentials (ERP). Adults with (n = 21) and without (n = 20) ASD performed a lexical decision task on emotion and neutral words while their brain activity was recorded. Both groups showed faster responses to emotion words compared to neutral, suggesting intact early processing of emotion in ASD. In the ERPs, the control group showed a typical late positive component (LPC) at 400-600 ms for emotion words compared to neutral, while the ASD group showed no LPC. The between-group difference in LPC amplitude was significant, suggesting that emotion words were processed differently by individuals with ASD, although their behavioral performance was similar to that of typical individuals

Abstract

We describe the calls of Stumpffia be Köhler, Vences, D’Cruze & Glaw, 2010. This is the first call description made for a species belonging to the large-bodied northern Madagascan radiation of Stumpffia Boettger, 1881. Stumpffia is a genus of small (~9–28 mm) microhylid frogs in the Madagascar-endemic subfamily Cophylinae Cope. Little is known about their reproductive strategies. Most species are assumed to lay their eggs in foam nests in the leaf litter of Madagascar’s humid and semi-humid forests (Glaw & Vences 1994; Klages et al. 2013). They exhibit some degree of parental care, with the males guarding the nest after eggs are laid (Klages et al. 2013). The bioacoustic repertoire of these frogs is thought to be limited, and there are two distinct call structures known for the genus: the advertisement call of the type species, S. psologlossa Boettger, 1881, is apparently unique in being a trill of notes repeated in short succession. All other species from which calls are known emit single, whistling or chirping notes (Vences & Glaw 1991; Vences et al. 2006).

Abstract

Commonly known for their ability to echolocate, bats also use a wide variety of social vocalizations to communicate with one another. However, the full vocal repertoires of relatively few bat species have been studied thus far. The present study examined the vocal repertoire of the pale spear-nosed bat, Phyllostomus discolor, in a social roosting context. Based on visual examination of spectrograms and subsequent quantitative analysis of syllables, eight distinct syllable classes were defined, and their prevalence in different behavioral contexts was examined. Four more syllable classes were observed in low numbers and are described here as well. These results show that P. discolor possesses a rich vocal repertoire, which includes vocalizations comparable to previously reported repertoires of other bat species as well as vocalizations previously undescribed. Our data provide detailed information about the temporal and spectral characteristics of syllables emitted by P. discolor, allowing for a better understanding of the communicative system and related behaviors of this species. Furthermore, this vocal repertoire will serve as a basis for future research using P. discolor as a model organism for vocal communication and vocal learning and it will allow for comparative studies between bat species.

Abstract

Although there is broad agreement that top-down expectations can facilitate lexical-semantic processing, the mechanisms driving these effects are still unclear. In particular, while previous electroencephalography (EEG) research has demonstrated a reduction in the N400 response to words in a supportive context, it is often challenging to dissociate facilitation due to bottom-up spreading activation from facilitation due to top-down expectations. The goal of the current study was to specifically determine the cortical areas associated with facilitation due to top-down prediction, using magnetoencephalography (MEG) recordings supplemented by EEG and functional magnetic resonance imaging (fMRI) in a semantic priming paradigm. In order to modulate expectation processes while holding context constant, we manipulated the proportion of related pairs across 2 blocks (10 and 50% related). Event-related potential results demonstrated a larger N400 reduction when a related word was predicted, and MEG source localization of activity in this time-window (350-450 ms) localized the differential responses to left anterior temporal cortex. fMRI data from the same participants support the MEG localization, showing contextual facilitation in left anterior superior temporal gyrus for the high expectation block only. Together, these results provide strong evidence that facilitatory effects of lexical-semantic prediction on the electrophysiological response 350-450 ms postonset reflect modulation of activity in left anterior temporal cortex.

Abstract

As visual media spread to all domains of public and scientific life, nonverbal behavior is taking its place as an important form of communication alongside the written and spoken word. An objective and reliable method of analysis for hand movement behavior and gesture is therefore currently required in various scientific disciplines, including psychology, medicine, linguistics, anthropology, sociology, and computer science. However, no adequate common methodological standards have been developed thus far. Many behavioral gesture-coding systems lack objectivity and reliability, and automated methods that register specific movement parameters often fail to show validity with regard to psychological and social functions. To address these deficits, we have combined two methods, an elaborated behavioral coding system and an annotation tool for video and audio data. The NEUROGES–ELAN system is an effective and user-friendly research tool for the analysis of hand movement behavior, including gesture, self-touch, shifts, and actions. Since its first publication in 2009 in Behavior Research Methods, the tool has been used in interdisciplinary research projects to analyze a total of 467 individuals from different cultures, including subjects with mental disease and brain damage. Partly on the basis of new insights from these studies, the system has been revised methodologically and conceptually. The article presents the revised version of the system, including a detailed study of reliability. The improved reproducibility of the revised version makes NEUROGES–ELAN a suitable system for basic empirical research into the relation between hand movement behavior and gesture and cognitive, emotional, and interactive processes and for the development of automated movement behavior recognition methods.

Abstract

Learning the syntax of a second language (L2) often represents a big challenge to L2 learners. Previous research on syntactic processing in L2 has mainly focused on how L2 speakers respond to "objective" syntactic violations, that is, phrases that are incorrect by native standards. In this study, we investigate how L2 learners, in particular those of less than near-native proficiency, process phrases that deviate from their own, "subjective," and often incorrect syntactic representations, that is, whether they use these subjective and idiosyncratic representations during sentence comprehension. We study this within the domain of grammatical gender in a population of German learners of Dutch, for which systematic errors of grammatical gender are well documented. These L2 learners as well as a control group of Dutch native speakers read Dutch sentences containing gender-marked determinernoun phrases in which gender agreement was either (objectively) correct or incorrect. Furthermore, the noun targets were selected such that, in a high proportion of nouns, objective and subjective correctness would differ for German learners. The ERP results show a syntactic violation effect (P600) for objective gender agreement violations for native, but not for nonnative speakers. However, when the items were re-sorted for the L2 speakers according to subjective correctness (as assessed offline), the P600 effect emerged as well. Thus, rather than being insensitive to violations of gender agreement, L2 speakers are similarly sensitive as native speakers but base their sensitivity on their subjective-sometimes incorrect-representations.

Abstract

Bilingual language control (BLC) is a much-debated issue in recent literature. Some models assume BLC is achieved by various types of inhibition of the non-target language, whereas other models do not assume any inhibitory mechanisms. In an event-related potential (ERP) study involving a long-lag morphological priming paradigm, participants were required to name pictures and read aloud words in both their L1 (Dutch) and L2 (English). Switch blocks contained intervening L1 items between L2 primes and targets, whereas non-switch blocks contained only L2 stimuli. In non-switch blocks, target picture names that were morphologically related to the primes were named faster than unrelated control items. In switch blocks, faster response latencies were recorded for morphologically related targets as well, demonstrating the existence of morphological priming in the L2. However, only in non-switch blocks, ERP data showed a reduced N400 trend, possibly suggesting that participants made use of a post-lexical checking mechanism during the switch block.

Abstract

Humans are adept at understanding speech despite the fact that our natural listening environment is often filled with interference. An example of this capacity is phoneme restoration, in which part of a word is completely replaced by noise, yet listeners report hearing the whole word. The neurological basis for this unconscious fill-in phenomenon is unknown, despite being a fundamental characteristic of human hearing. Here, using direct cortical recordings in humans, we demonstrate that missing speech is restored at the acoustic-phonetic level in bilateral auditory cortex, in real-time. This restoration is preceded by specific neural activity patterns in a separate language area, left frontal cortex, which predicts the word that participants later report hearing. These results demonstrate that during speech perception, missing acoustic content is synthesized online from the integration of incoming sensory cues and the internal neural dynamics that bias word-level expectation and prediction.

Abstract

There is great variation in whether foreign sounds in loanwords are adapted or retained. Importantly, the retention of foreign sounds can lead to a sound change in the language. We propose that social factors influence the likelihood of loanword sound adaptation, and use this case to introduce a novel experimental paradigm for studying language change that captures the role of social factors. Specifically, we show that the relative prestige of the donor language in the loanword's semantic domain influences the rate of sound adaptation. We further show that speakers adapt to the performance of their ‘community’, and that this adaptation leads to the creation of a norm. The results of this study are thus the first to show an effect of social factors on loanword sound adaptation in an experimental setting. Moreover, they open up a new domain of experimentally studying language change in a manner that integrates social factors

Abstract

Speech perception is known to be influenced by listeners’ expectations of the speaker. This paper tests whether the demographic makeup of individuals’ communities can influence their perception of foreign sounds by influencing their expectations of the language. Using online experiments with participants from all across the U.S. and matched census data on the proportion of Spanish and other foreign language speakers in participants’ communities, this paper shows that the demo- graphic makeup of individuals’ communities influences their expectations of foreign languages to have an alveolar trill versus a tap (Experiment 1), as well as their consequent perception of these sounds (Experiment 2). Thus, the paper shows that while individuals’ expectations of foreign lan- guage to have a trill occasionally lead them to misperceive a tap in a foreign language as a trill, a higher proportion of non-trill language speakers in one’s community decreases this likelihood. These results show that individuals’ environment can influence their perception by shaping their linguistic expectations

Abstract

People differ in the size of their social network, and thus in the properties of the linguistic input they receive. This article examines whether differences in social network size influence individuals’ linguistic skills in their native language, focusing on global comprehension of evaluative language. Study 1 exploits the natural variation in social network size and shows that individuals with larger social networks are better at understanding the valence of restaurant reviews. Study 2 manipulated social network size by randomly assigning participants to learn novel evaluative words as used by two (small network) versus eight (large network) speakers. It replicated the finding from Study 1, showing that those exposed to a larger social network were better at comprehending the valence of product reviews containing the novel words that were written by novel speakers. Together, these studies show that the size of one's social network can influence success at language comprehension. They thus open the door to research on how individuals’ lifestyle and the nature of their social interactions can influence linguistic skills.

Abstract

Although it is known that words acquire their meanings partly from the contexts in which they are used, we proposed that the way in which words are processed can also influence their representation. We further propose that individual differences in the way that words are processed can consequently lead to individual differences in the way that they are represented. Specifically, we showed that executive control influences linguistic representations by influencing the coactivation of competing and reinforcing terms. Consequently, people with poorer executive control perceive the meanings of homonymous terms as being more similar to one another, and those of polysemous terms as being less similar to one another, than do people with better executive control. We also showed that bilinguals with poorer executive control experience greater cross-linguistic interference than do bilinguals with better executive control. These results have implications for theories of linguistic representation and language organization.

Abstract

Prediction of upcoming words facilitates language processing. Individual differences in social experience, however, might influence prediction ability by influencing input variability and representativeness. This paper explores how individual differences in social network size influence prediction and how this influence differs across linguistic levels. In Experiment 1, participants predicted likely sentence completions from several plausible endings differing in meaning or only form (e.g. work vs. job). In Experiment 2, participants’ pupil size was measured as they listened to sentences whose ending was the dominant one or deviated from it in either meaning or form. Both experiments show that people with larger social networks are better at predicting upcoming meanings but not the form they would take. The results thus show that people with different social experience process language differently, and shed light on how social dynamics interact with the structure of the linguistic level to influence learning of linguistic patterns.

Abstract

There is great variability in whether foreign sounds in loanwords are adapted, such that segments show cross-word and cross-situational variation in adaptation. Previous research proposed that word frequency, speakers' level of bilingualism and neighborhoods' level of bilingualism can explain such variability. We test for the effect of these factors and propose two additional factors: interlocutors' level of bilingualism and the prestige of the donor language in the loanword's domain. Analyzing elicited productions of loanwords from Spanish into Mexicano in a village where Spanish and Mexicano enjoy prestige in complementary domains, we show that interlocutors' bilingualism and prestige influence the rate of sound adaptation. Additionally, we find that speakers accommodate to their interlocutors, regardless of the interlocutors' level of bilingualism. As retention of foreign sounds can lead to sound change, these results show that social factors can influence changes in a language's sound system.

Abstract

Models of language learning often assume that we learn from all the input we receive. This assumption is particularly strong in the domain of short-term and long-term grammatical convergence, where researchers argue that grammatical convergence is mostly an automatic process insulated from social factors. This paper shows that the degree to which individuals learn from grammatical input is modulated by social and contextual factors, such as the degree to which the speaker is liked and their social standing. Furthermore, such modulation is found in experiments that test generalized learning rather than convergence during the interaction. This paper thus shows the importance of the social context in grammatical learning, and indicates that the social context should be integrated into models of language learning.

Abstract

Inhibition is known to play a role in speech perception and has been hypothesized to likewise influence speech production. In this paper we test whether individual differences in inhibitory skill can lead to individual differences in phonological representations in perception and production. We further examine whether the type of inhibition that influences phonological representation is domain-specific or domain-general. Native French speakers read aloud sentences with words containing a voiced stop that either have a voicing neighbor (target) or not (control). The duration of pre-voicing was measured. Participants similarly performed a lexical decision task on versions of these target and matched control words whose pre-voicing duration was manipulated. Lastly, participants performed linguistic and non-linguistic inhibition tasks. Results indicate that the lower speakers' linguistic or non-linguistic inhibition is, the easier it is for them to recognize words with a voiceless neighbor when these words have a shorter, intermediate, pre-voicing rather than a longer one. Inhibitory skill did not predict recognition time for control words, indicating that the effect was due to the greater activation of the voiceless neighbor. Inhibition did not predict pre-voicing duration in production. These results indicate that individual differences in cognitive skills can influence phonological representations in speech perception.

Abstract

The order of acquisition of Dutch syllable types by first language learners is analyzed as following from an initial ranking and subsequent rerankings of constraints in an optimality theoretic grammar. Initially, structural constraints are all ranked above faithfulness constraints, leading to core syllable (CV) productions only. Subsequently, faithfulness gradually rises to the highest position in the ranking, allowing more and more marked syllable types to appear in production. Local conjunctions of Structural constraints allow for a more detailed analysis.

Abstract

Preparing words in speech production is normally a fast and accurate process. We generate them two or three per second in fluent conversation; and overtly naming a clear picture of an object can easily be initiated within 600 msec after picture onset. The underlying process, however, is exceedingly complex. The theory reviewed in this target article analyzes this process as staged and feedforward. After a first stage of conceptual preparation, word generation proceeds through lexical selection, morphological and phonological encoding, phonetic encoding, and articulation itself. In addition, the speaker exerts some degree of output control, by monitoring of self-produced internal and overt speech. The core of the theory, ranging from lexical selection to the initiation of phonetic encoding, is captured in a computational model, called WEAVER + +. Both the theory and the computational model have been developed in interaction with reaction time experiments, particularly in picture naming or related word production paradigms, with the aim of accounting. for the real-time processing in normal word production. A comprehensive review of theory, model, and experiments is presented. The model can handle some of the main observations in the domain of speech errors (the major empirical domain for most other theories of lexical access), and the theory opens new ways of approaching the cerebral organization of speech production by way of high-temporal-resolution imaging.

Abstract

The purpose of this study was to relate a psycholinguistic processing model of picture naming to the dynamics of cortical activation during picture naming. The activation was recorded from eight Dutch subjects with a whole-head neuromagnetometer. The processing model, based on extensive naming latency studies, is a stage model. In preparing a picture's name, the speaker performs a chain of specific operations. They are, in this order, computing the visual percept, activating an appropriate lexical concept, selecting the target word from the mental lexicon, phonological encoding, phonetic encoding, and initiation of articulation. The time windows for each of these operations are reasonably well known and could be related to the peak activity of dipole sources in the individual magnetic response patterns. The analyses showed a clear progression over these time windows from early occipital activation, via parietal and temporal to frontal activation. The major specific findings were that (1) a region in the left posterior temporal lobe, agreeing with the location of Wernicke's area, showed prominent activation starting about 200 msec after picture onset and peaking at about 350 msec, (i.e., within the stage of phonological encoding), and (2) a consistent activation was found in the right parietal cortex, peaking at about 230 msec after picture onset, thus preceding and partly overlapping with the left temporal response. An interpretation in terms of the management of visual attention is proposed.

Abstract

The evolution of speech and language has been a returning topic in the language sciences since the so-called “cognitive revolution.”

Abstract

Research on spoken word production has been approached from two angles. In one research tradition, the analysis of spontaneous or induced speech errors led to models that can account for speech error distributions. In another tradition, the measurement of picture naming latencies led to chronometric models accounting for distributions of reaction times in word production. Both kinds of models are, however, dealing with the same underlying processes: (1) the speaker’s selection of a word that is semantically and syntactically appropriate; (2) the retrieval of the word’s phonological properties; (3) the rapid syllabification of the word in context; and (4) the preparation of the corresponding articulatory gestures. Models of both traditions explain these processes in terms of activation spreading through a localist, symbolic network. By and large, they share the main levels of representation: conceptual/semantic, syntactic, phonological and phonetic. They differ in various details, such as the amount of cascading and feedback in the network. These research traditions have begun to merge in recent years, leading to highly constructive experimentation. Currently, they are like two similar knives honing each other. A single pair of scissors is in the making.

Abstract

This commentary discusses whether abstract metrical frames are stored. For stress-assigning languages (e.g., Dutch and English), which have a dominant stress pattern, metrical frames are stored only for words that deviate from the default stress pattern. The majority of the words in these languages are produced without retrieving any independent syllabic or metrical frame.

Abstract

This paper considers the AGL literature from a psycholinguistic perspective. It first presents a taxonomy of the experimental familiarization test procedures used, which is followed by a consideration of shortcomings and potential improvements of the empirical methodology. It then turns to reconsidering the issue of grammar learning from the point of view of acquiring constraints, instead of the traditional AGL approach in terms of acquiring sets of rewrite rules. This is, in particular, a natural way of handling long‐distance dependences. The final section addresses an underdeveloped issue in the AGL literature, namely how to detect latent hierarchical structure in AGL response patterns.

Abstract

The core issue in the 19-century sources of psycholinguistics was the question, "Where does language come from?'' This genetic perspective unified the study of the ontogenesis, the phylogenesis, the microgenesis, and to some extent the neurogenesis of language. This paper makes the point that this original perspective is still a valid and attractive one. It is exemplified by a discussion of the genesis of spoken words.

Abstract

neffability, the degree to which percepts or concepts resist linguistic coding, is a fairly unexplored nook of cognitive science. Although philosophical preoccupations with qualia or nonconceptual content certainly touch upon the area, there has been little systematic thought and hardly any empirical work in recent years on the subject. We argue that ineffability is an important domain for the cognitive sciences. For examining differential ineffability across the senses may be able to tell us important things about how the mind works, how different modalities talk to one another, and how language does, or does not, interact with other mental faculties.

Abstract

This commentary raises two issues: (1) Language processing is hastened not only by internal pressures but also externally by turntaking in language use; (2) the theory requires nested levels of processing, but linguistic levels do not fully nest; further, it would seem to require multiple memory buffers, otherwise there’s no obvious treatment for discontinuous structures, or for verbatim recall.

Abstract

Philosophers, psychologists, and linguists have argued that spatial conception is pivotal to cognition in general, providing a general, egocentric, and universal framework for cognition as well as metaphors for conceptualizing many other domains. But in an aboriginal community in Northern Queensland, a system of cardinal directions informs not only language, but also memory for arbitrary spatial arrays and directions. This work suggests that fundamental cognitive parameters, like the system of coding spatial locations, can vary cross-culturally, in line with the language spoken by a community. This opens up the prospect of a fruitful dialogue between anthropology and the cognitive sciences on the complex interaction between cultural and universal factors in the constitution of mind.

Abstract

One reason for the apparent gulf between animal and human communication systems is that the focus has been on the presence or the absence of language as a complex expressive system built on speech. But language normally occurs embedded within an interactional exchange of multi-modal signals. If this larger perspective takes central focus, then it becomes apparent that human communication has a layered structure, where the layers may be plausibly assigned different phylogenetic and evolutionary origins—especially in the light of recent thoughts on the emergence of voluntary breathing and spoken language. This perspective helps us to appreciate the different roles that the different modalities play in human communication, as well as how they function as one integrated system despite their different roles and origins. It also offers possibilities for reconciling the ‘gesture-first hypothesis’ with that of gesture and speech having evolved together, hand in hand—or hand in mouth, rather—as one system.

Abstract

Most language usage is interactive, involving rapid turn-taking. The turn-taking system has a number of striking properties: turns are short and responses are remarkably rapid, but turns are of varying length and often of very complex construction such that the underlying cognitive processing is highly compressed. Although neglected in cognitive science, the system has deep implications for language processing and acquisition that are only now becoming clear. Appearing earlier in ontogeny than linguistic competence, it is also found across all the major primate clades. This suggests a possible phylogenetic continuity, which may provide key insights into language evolution.

Abstract

The present paper discusses the benefits and challenges of token-based typology, which takes into account the frequencies of words and constructions in language use. This approach makes it possible to introduce new criteria for language classification, which would be difficult or impossible to achieve with the traditional, type-based approach. This point is illustrated by several quantitative studies of word order variation, which can be measured as entropy at different levels of granularity. I argue that this variation can be explained by general functional mechanisms and pressures, which manifest themselves in language use, such as optimization of processing (including avoidance of ambiguity) and grammaticalization of predictable units occurring in chunks. The case studies are based on multilingual corpora, which have been parsed using the Universal Dependencies annotation scheme.

Abstract

Morphology is the aspect of language concerned with the internal structure of words. In the past decades, a large body of masked priming (behavioral and neuroimaging) data has suggested that the visual word recognition system automatically decomposes any morphologically complex word into a stem and its constituent morphemes. Yet the reliance of morphology on other reading processes (e.g., orthography and semantics), as well as its underlying neuronal mechanisms are yet to be determined. In the current magnetoencephalography study, we addressed morphology from the perspective of the unification framework, that is, by applying the Hold/Release paradigm, morphological unification was simulated via the assembly of internal morphemic units into a whole word. Trials representing real words were divided into words with a transparent (true) or a nontransparent (pseudo) morphological relationship. Morphological unification of truly suffixed words was faster and more accurate and additionally enhanced induced oscillations in the narrow gamma band (60–85 Hz, 260–440 ms) in the left posterior occipitotemporal junction. This neural signature could not be explained by a mere automatic lexical processing (i.e., stem perception), but more likely it related to a semantic access step during the morphological unification process. By demonstrating the validity of unification at the morphological level, this study contributes to the vast empirical evidence on unification across other language processes. Furthermore, we point out that morphological unification relies on the retrieval of lexical semantic associations via induced gamma band oscillations in a cerebral hub region for visual word form processing.

Abstract

A rare germline duplication upstream of the bone morphogenetic protein antagonist GREM1 causes a Mendelian-dominant predisposition to colorectal cancer (CRC). The underlying disease mechanism is strong, ectopic GREM1 overexpression in the intestinal epithelium. Here, we confirm that a common GREM1 polymorphism, rs16969681, is also associated with CRC susceptibility, conferring ∼20% differential risk in the general population. We hypothesized the underlying cause to be moderate differences in GREM1 expression. We showed that rs16969681 lies in a region of active chromatin with allele- and tissue-specific enhancer activity. The CRC high-risk allele was associated with stronger gene expression, and higher Grem1 mRNA levels increased the intestinal tumor burden in ApcMin mice. The intestine-specific transcription factor CDX2 and Wnt effector TCF7L2 bound near rs16969681, with significantly higher affinity for the risk allele, and CDX2 overexpression in CDX2/GREM1-negative cells caused re-expression of GREM1. rs16969681 influences CRC risk through effects on Wnt-driven GREM1 expression in colorectal tumors.

Abstract

Oscillatory neural dynamics have been steadily receiving more attention as a robust and temporally precise signature of network activity related to language processing. We have recently proposed that oscillatory dynamics in the beta and gamma frequency ranges measured during sentence-level comprehension might be best explained from a predictive coding perspective. Under our proposal we related beta oscillations to both the maintenance/change of the neural network configuration responsible for the construction and representation of sentence-level meaning, and to top–down predictions about upcoming linguistic input based on that sentence-level meaning. Here we zoom in on these particular aspects of our proposal, and discuss both old and new supporting evidence. Finally, we present some preliminary magnetoencephalography data from an experiment comparing Dutch subject- and object-relative clauses that was specifically designed to test our predictive coding framework. Initial results support the first of the two suggested roles for beta oscillations in sentence-level language comprehension.

Abstract

For native speakers, many studies suggest a link between oscillatory neural activity in the beta frequency range and syntactic processing. For late second language (L2) learners on the other hand, the extent to which the neural architecture supporting syntactic processing is similar to or different from that of native speakers is still unclear. In a series of four experiments, we used electroencephalography to investigate the link between beta oscillatory activity and the processing of grammatical gender agreement in Dutch determiner-noun pairs, for Dutch native speakers, and for German L2 learners of Dutch. In Experiment 1 we show that for native speakers, grammatical gender agreement violations are yet another among many syntactic factors that modulate beta oscillatory activity during sentence comprehension. Beta power is higher for grammatically acceptable target words than for those that mismatch in grammatical gender with their preceding determiner. In Experiment 2 we observed no such beta modulations for L2 learners, irrespective of whether trials were sorted according to objective or subjective syntactic correctness. Experiment 3 ruled out that the absence of a beta effect for the L2 learners in Experiment 2 was due to repetition of the target nouns in objectively correct and incorrect determiner-noun pairs. Finally, Experiment 4 showed that when L2 learners are required to explicitly focus on grammatical information, they show modulations of beta oscillatory activity, comparable to those of native speakers, but only when trials are sorted according to participants’ idiosyncratic lexical representations of the grammatical gender of target nouns. Together, these findings suggest that beta power in L2 learners is sensitive to violations of grammatical gender agreement, but only when the importance of grammatical information is highlighted, and only when participants' subjective lexical representations are taken into account.

Abstract

Schizophrenia is a common and complex mental disorder with neuroimaging alterations. Recent neuroanatomical pattern recognition studies attempted to distinguish individuals with schizophrenia by structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI). 1, 2 Applications of cutting-edge machine learning approaches in structural neuroimaging studies have revealed potential pathways to classification of schizophrenia based on regional gray matter volume (GMV) or density or cortical thickness. 3–5 Additionally, cortical folding may have high discriminatory value in correctly identifying symptom severity in schizophrenia. 6 Regional GMV and cortical thickness have also been combined in attempts to differentiate individuals with schizophrenia from healthy controls (HCs). 7 Applications of machine learning algorithms to diffusion imaging data analysis to predict individuals with first-episode schizophrenia (FES) have achieved encouraging accuracy. 8–10 White matter (WM) abnormalities in schizophrenia as estimated by DTI appear to be present in the early stage of the disorder, most likely reflecting the developmental stage of the sample of interest.

Abstract

Identifying data-driven biotypes of major depressive disorder (MDD) has promise for the clarification of diagnostic heterogeneity. However, few studies have focused on white-matter abnormalities for MDD subtyping. This study included 116 patients with MDD and 118 demographically-matched healthy controls assessed by diffusion tensor imaging and neurocognitive evaluation. Hierarchical clustering was applied to the major fiber tracts, in conjunction with tract-based spatial statistics, to reveal white-matter alterations associated with MDD. Clinical and neurocognitive differences were compared between identified subgroups and healthy controls. With fractional anisotropy extracted from 20 fiber tracts, cluster analysis revealed 3 subgroups based on the patterns of abnormalities. Patients in each subgroup versus healthy controls showed a stepwise pattern of white-matter alterations as follows: subgroup 1 (25.9% of patient sample), widespread white-matter disruption; subgroup 2 (43.1% of patient sample), intermediate and more localized abnormalities in aspects of the corpus callosum and left cingulate; and subgroup 3 (31.0% of patient sample), possible mild alterations, but no statistically significant tract disruption after controlling for family-wise error. The neurocognitive impairment in each subgroup accompanied the white-matter alterations: subgroup 1, deficits in sustained attention and delayed memory; subgroup 2, dysfunction in delayed memory; and subgroup 3, no significant deficits. Three subtypes of white-matter abnormality exist in individuals with major depression, those having widespread abnormalities suffering more neurocognitive impairments, which may provide evidence for parsing the heterogeneity of the disorder and help optimize type-specific treatment approaches.

Abstract

Over the last thirty years, evolutionary linguistics has grown as a data-driven, interdisciplinary field and received accelerated interest due to its adoption of modern research methodologies. This growth is dependant upon the methods used to both disseminate and foster discussion of research by the larger academic community. We argue that the internet is increasingly being used as an efficient means of finding and presenting research. The traditional journal format for disseminating knowledge was well-designed within the confines of print publication. With the tools afforded to us by technology and the internet, the evolutionary linguistics research community is able to compensate for the necessary shortcomings of the journal format. We evaluate examples of how research blogging has aided language scientists. We review the state of the field for online, real-time academic debate, by covering particular instances of post- publication review and their reaction. We conclude by considering how evolutionary linguistics as a field can potentially benefit from using the internet

Abstract

Sleep loss can alter extrinsic, task-related functional MRI signals involved in attention, memory, and executive function. However, the effects of sleep loss on brain structure have not been well characterized. Recent studies with patients with sleep disorders and animal models have demonstrated reduction of regional brain structure in the hippocampus and thalamus. In this study, using T1-weighted MRI, we examined the change of regional gray matter volume in healthy adults after long-term total sleep deprivation (∼72 h). Regional volume changes were explored using voxel-based morphometry with a paired two-sample t-test. The results revealed significant loss of gray matter volume in the thalamus but not in the hippocampus. No overall decrease in whole brain gray matter volume was noted after sleep deprivation. As expected, sleep deprivation significantly reduced visual vigilance as assessed by the continuous performance test, and this decrease was correlated significantly with reduced regional gray matter volume in thalamic regions. This study provides the first evidence for sleep loss-related changes in gray matter in the healthy adult brain.

Abstract

This article is about whether the factors which drive online sharing of non-scholarly content also apply to academic journal titles. It uses Altmetric scores as a measure of online attention to articles from Frontiers in Psychology published in 2013 and 2014. Article titles with result-oriented positive framing and more interesting phrasing receive higher Altmetric scores, i.e., get more online attention. Article titles with wordplay and longer article titles receive lower Altmetric scores. This suggests that the same factors that affect how widely non-scholarly content is shared extend to academia, which has implications for how academics can make their work more likely to have more impact.

Abstract

Sound symbolism is increasingly understood as involving iconicity, or perceptual analogies and cross-modal correspondences between form and meaning, but the search for its functional and neural correlates is ongoing. Here we study how people learn sound-symbolic words, using behavioural, electrophysiological and individual difference measures. Dutch participants learned Japanese ideophones —lexical sound-symbolic words— with a translation of either the real meaning (in which form and meaning show cross-modal correspondences) or the opposite meaning (in which form and meaning show cross-modal clashes). Participants were significantly better at identifying the words they learned in the real condition, correctly remembering the real word pairing 86.7% of the time, but the opposite word pairing only 71.3% of the time. Analysing event-related potentials (ERPs) during the test round showed that ideophones in the real condition elicited a greater P3 component and late positive complex than ideophones in the opposite condition. In a subsequent forced choice task, participants were asked to guess the real translation from two alternatives. They did this with 73.0% accuracy, well above chance level even for words they had encountered in the opposite condition, showing that people are generally sensitive to the sound-symbolic cues in ideophones. Individual difference measures showed that the ERP effect in the test round of the learning task was greater for participants who were more sensitive to sound symbolism in the forced choice task. The main driver of the difference was a lower amplitude of the P3 component in response to ideophones in the opposite condition, suggesting that people who are more sensitive to sound symbolism may have more difficulty to suppress conflicting cross-modal information. The findings provide new evidence that cross-modal correspondences between sound and meaning facilitate word learning, while cross-modal clashes make word learning harder, especially for people who are more sensitive to sound symbolism.

Abstract

The existence of sound-symbolism (or a non-arbitrary link between form and meaning) is well-attested. However, sound-symbolism has mostly been investigated with nonwords in forced choice tasks, neither of which are representative of natural language. This study uses ideophones, which are naturally occurring sound-symbolic words that depict sensory information, to investigate how sensitive Dutch speakers are to sound-symbolism in Japanese in a learning task. Participants were taught 2 sets of Japanese ideophones; 1 set with the ideophones’ real meanings in Dutch, the other set with their opposite meanings. In Experiment 1, participants learned the ideophones and their real meanings much better than the ideophones with their opposite meanings. Moreover, despite the learning rounds, participants were still able to guess the real meanings of the ideophones in a 2-alternative forced-choice test after they were informed of the manipulation. This shows that natural language sound-symbolism is robust beyond 2-alternative forced-choice paradigms and affects broader language processes such as word learning. In Experiment 2, participants learned regular Japanese adjectives with the same manipulation, and there was no difference between real and opposite conditions. This shows that natural language sound-symbolism is especially strong in ideophones, and that people learn words better when form and meaning match. The highlights of this study are as follows: (a) Dutch speakers learn real meanings of Japanese ideophones better than opposite meanings, (b) Dutch speakers accurately guess meanings of Japanese ideophones, (c) this sensitivity happens despite learning some opposite pairings, (d) no such learning effect exists for regular Japanese adjectives, and (e) this shows the importance of sound-symbolism in scaffolding language learning

Abstract

In the emerging field of cross-linguistic studies on language production, one particularly interesting line of inquiry is possible differences between English and Japanese in ordering words and phrases. Previous research gives rise to the idea that there is a difference in accessing meaning versus form during linearization between these two languages. This assumption is based on observations of language-specific effects of the length factor on the order of phrases (short-before-long in English, long-before-short in Japanese). We contribute to the cross-linguistic exploration of such differences by investigating the variables underlying the internal order of NP conjuncts in spoken English and Japanese. Our quantitative analysis shows that similar influences underlie the ordering process across the two languages. Thus we do not find evidence for the aforementioned difference in accessing meaning versus form with this syntactic phenomenon. With regard to length, Japanese also exhibits a short-before-long preference. However, this tendency is significantly weaker in Japanese than in English, which we explain through an attenuating influence of the typical Japanese phrase structure pattern on the universal effect of short phrases being more accessible. We propose that a similar interaction between entrenched long-before-short schemas and universal accessibility effects is responsible for the varying effects of length in Japanese.

Abstract

Purpose While decades of research were devoted to study generation mechanisms of spontaneous spike and wave discharges (SWD), little attention has been paid to network mechanisms associated with the spontaneous termination of SWD. In the current study coupling-dynamics at the onset and termination of SWD were studied in an extended part of the cortico-thalamo-cortical system of freely moving, genetic absence epileptic WAG/Rij rats. Methods Local-field potential recordings of 16 male WAG/Rij rats, equipped with multiple electrodes targeting layer 4 to 6 of the somatosensory-cortex (ctx4, ctx5, ctx6), rostral and caudal reticular thalamic nucleus (rRTN & cRTN), Ventral Postero Medial (VPM), anterior- (ATN) and posterior (Po) thalamic nucleus, were obtained. Six seconds lasting pre-SWD->SWD, SWD->post SWD and control periods were analyzed with time-frequency methods and between-region interactions were quantified with frequencyresolved Granger Causality (GC) analysis. Results Most channel-pairs showed increases in GC lasting from onset to offset of the SWD. While for most thalamo-thalamic pairs a dominant coupling direction was found during the complete SWD, most cortico-thalamic pairs only showed a dominant directional drive (always from cortex to thalamus) during the first 500ms of SWD. Channel-pair ctx4-rRTN showed a longer lasting dominant cortical drive, which stopped 1.5 sec prior to SWD offset. This early decrease in directional coupling was followed by an increase in directional coupling from cRTN to rRTN 1 sec prior to SWD offset. For channel pairs ctx5-Po and ctx6-Po the heightened cortex->thalamus coupling remained until 1.5 sec following SWD offset, while the thalamus->cortex coupling for these pairs stopped at SWD offset. Conclusion The high directional coupling from somatosensory cortex to the thalamus at SWD onset is in good agreement with the idea of a cortical epileptic focus that initiates and entrains other brain structures into seizure activity. The decrease of cortex to rRTN coupling as well as the increased coupling from cRTN to rRTN preceding SWD termination demonstrate that SWD termination is a gradual process that involves both cortico-thalamic as well as intrathalamic processes. The rostral RTN seems to be an important resonator for SWD and relevant for maintenance, while the cRTN might inhibit this oscillation. The somatosensory cortex seems to attempt to reinitiate SWD following its offset via its strong coupling to the posterior thalamus.

Abstract

Motivation: Runs of homozygosity (ROH) are sizable chromosomal stretches of homozygous genotypes, ranging in length from tens of kilobases to megabases. ROHs can be relevant for population and medical genetics, playing a role in predisposition to both rare and common disorders. ROHs are commonly detected by single nucleotide polymorphism (SNP) microarrays, but attempts have been made to use whole-exome sequencing (WES) data. Currently available methods developed for the analysis of uniformly spaced SNP-array maps do not fit easily to the analysis of the sparse and non-uniform distribution of the WES target design. Results: To meet the need of an approach specifically tailored to WES data, we developed (HM2)-M-3, an original algorithm based on heterogeneous hidden Markov model that incorporates inter-marker distances to detect ROH from WES data. We evaluated the performance of H-3 M-2 to correctly identify ROHs on synthetic chromosomes and examined its accuracy in detecting ROHs of different length (short, medium and long) from real 1000 genomes project data. H3M2 turned out to be more accurate than GERMLINE and PLINK, two state-of-the-art algorithms, especially in the detection of short and medium ROHs

Abstract

RTs in conversation, with average gaps of 200 msec and often less, beat standard RTs, despite the complexity of response and the lag in speech production (600 msec or more). This can only be achieved by anticipation of timing and content of turns in conversation, about which little is known. Using EEG and an experimental task with conversational stimuli, we show that estimation of turn durations are based on anticipating the way the turn would be completed. We found a neuronal correlate of turn-end anticipation localized in ACC and inferior parietal lobule, namely a beta-frequency desynchronization as early as 1250 msec, before the end of the turn. We suggest that anticipation of the other's utterance leads to accurately timed transitions in everyday conversations.

Abstract

From Plato to Pinker there has been the common belief that the experience of a smell is impossible to put into words. Decades of studies have confirmed this observation. But the studies to date have focused on participants from urbanized Western societies. Cross-cultural research suggests that there may be other cultures where odors play a larger role. The Jahai of the Malay Peninsula are one such group. We tested whether Jahai speakers could name smells as easily as colors in comparison to a matched English group. Using a free naming task we show on three different measures that Jahai speakers find it as easy to name odors as colors, whereas English speakers struggle with odor naming. Our findings show that the long-held assumption that people are bad at naming smells is not universally true. Odors are expressible in language, as long as you speak the right language.

Abstract

People engage in simulation when reading literary narratives. In this study, we tried to pinpoint how different kinds of simulation (perceptual and motor simulation, mentalising) affect reading behaviour. Eye-tracking (gaze durations, regression probability) and questionnaire data were collected from 102 participants, who read three literary short stories. In a pre-test, 90 additional participants indicated which parts of the stories were high in one of the three kinds of simulation-eliciting content. The results show that motor simulation reduces gaze duration (faster reading), whereas perceptual simulation and mentalising increase gaze duration (slower reading). Individual differences in the effect of simulation on gaze duration were found, which were related to individual differences in aspects of story world absorption and story appreciation. These findings suggest fundamental differences between different kinds of simulation and confirm the role of simulation in absorption and appreciation.

Abstract

The distinctions between red and yellow or arm and hand may seem self-evident to English speakers, but they are not: Languages differ in the named distinctions they make. To help understand what constrains word meaning and how variation arises, we examined name choices in English, Dutch, Spanish, and Japanese for 36 instances of human locomotion. Naming patterns showed commonalities largely interpretable in terms of perceived physical similarities among the instances. There was no evidence for languages jointly ignoring salient physical distinctions to build meaning on other bases, nor for a shift in the basis of word meanings between parts of the domain of more vs. less importance to everyday life. Overall, the languages differed most notably in how many named distinctions they made, a form of variation that may be linked to linguistic typology. These findings, considered along with naming patterns from other domains, suggest recurring principles of constraint and variation across domains.

Abstract

Despite the efficiency with which language users typically process spoken language, a growing body of research finds substantial individual differences in both the speed and accuracy of spoken language processing potentially attributable to participants’ literacy skills. Against this background, the current study takes a look at the role of word reading skill in listener’s anticipation of upcoming spoken language input in children at the cusp of learning to read: if reading skills impact predictive language processing, then children at this stage of literacy acquisition should be most susceptible to the effects of reading skills on spoken language processing. We tested 8-year-old children on their prediction of upcoming spoken language input in an eye-tracking task. While children, like in previous studies to-date, were successfully able to anticipate upcoming spoken language input, there was a strong positive correlation between children’s word reading (but not their pseudo-word reading and meta-phonological awareness or their spoken word recognition) skills and their prediction skills. We suggest that these findings are most compatible with the notion that the process of learning orthographic representations during reading acquisition sharpens pre-existing lexical representations which in turn also supports anticipation of upcoming spoken words.

Abstract

The anticipation of the forthcoming behaviour of social interaction partners is a useful ability supporting interaction and communication between social partners. Associations and prediction based on the production system (in line with views that listeners use the production system covertly to anticipate what the other person might be likely to say) are two potential factors, which have been proposed to be involved in anticipatory language processing. We examined the influence of both factors on the degree to which listeners predict upcoming linguistic input. Are listeners more likely to predict book as an appropriate continuation of the sentence “The boy reads a”, based on the strength of the association between the words read and book (strong association) and read and letter (weak association)? Do more proficient producers predict more? What is the interplay of these two influences on prediction? The results suggest that associations influence language-mediated anticipatory eye gaze in two-year-olds and adults only when two thematically appropriate target objects compete for overt attention but not when these objects are presented separately. Furthermore, children’s prediction abilities are strongly related to their language production skills when appropriate target objects are presented separately but not when presented together. Both influences on prediction in language processing thus appear to be context-dependent. We conclude that multiple factors simultaneously influence listeners’ anticipation of upcoming linguistic input and that only such a dynamic approach to prediction can capture listeners’ prowess at predictive language processing.

Abstract

Other-initiated repair is an essential interactional practice to secure mutual understanding in everyday interaction. This article presents evidence from a large conversational corpus of a sign language, showing that signers of Argentine Sign Language (Lengua de Señas Argentina or ‘LSA’), like users of spoken languages, use a systematic set of linguistic formats and practices to indicate troubles of signing, seeing and understanding. The general aim of this article is to provide a general overview of the different visual-gestural linguistic patterns of other-initiated repair sequences in LSA. It also describes the quantitative distribution of other-initiated repair formats based on a collection of 213 cases. It describes the multimodal components of open and restricted types of repair initiators, and reports a previously undescribed implicit practice to initiate repair in LSA in comparison to explicitly produced formats. Part of a special issue presenting repair systems across a range of languages, this article contributes to a better understanding of the phenomenon of other-initiated repair in terms of visual and gestural practices in human interaction in both signed and spoken languages

Abstract

Prediction of upcoming input is thought to be a main characteristic of language processing (e.g. Altmann & Mirkovic, 2009; Dell & Chang, 2014; Federmeier, 2007; Ferreira & Chantavarin, 2018; Pickering & Gambi, 2018; Hale, 2001; Hickok, 2012; Huettig 2015; Kuperberg & Jaeger, 2016; Levy, 2008; Norris, McQueen, & Cutler, 2016; Pickering & Garrod, 2013; Van Petten & Luka, 2012). One of the main pillars of experimental support for this notion comes from studies that have attempted to measure electrophysiological markers of prediction when participants read or listened to sentences ending in highly predictable words. The N400, a negative-going and centro-parietally distributed component of the ERP occurring approximately 400ms after (target) word onset, has been frequently interpreted as indexing prediction of the word (or the semantic representations and/or the phonological form of the predicted word, see Kutas & Federmeier, 2011; Nieuwland, 2019; Van Petten & Luka, 2012; for review). A major difficulty for interpreting N400 effects in language processing however is that it has been difficult to establish whether N400 target word modulations conclusively reflect prediction rather than (at least partly) ease of integration. In the present exploratory study, we attempted to distinguish lexical prediction (i.e. ‘top-down’ activation) from lexical integration (i.e. ‘bottom-up’ activation) accounts of ERP N400 modulations in language processing.

Abstract

Successful dependency resolution during language comprehension relies on accessing certain representations in memory, and not others. We recently reported event-related potential (ERP) evidence that syntactically unavailable, intervening attractor-nouns interfered during comprehension of Spanish noun-phrase ellipsis (the determiner otra/otro): grammatically correct determiners that mismatched the gender of attractor-nouns elicited a sustained negativity as also observed for incorrect determiners (Martin, Nieuwland, & Carreiras, 2012). The current study sought to extend this novel finding in sentences containing object-extracted relative clauses, where the antecedent may be less prominent. Whereas correct determiners that matched the gender of attractor-nouns now elicited an early anterior negativity as also observed for mismatching determiners, the previously reported interaction pattern was replicated in P600 responses to subsequent words. Our results suggest that structural and gender information is simultaneously taken into account, providing further evidence for retrieval interference during comprehension of grammatical sentences.

Abstract

Human thought and language have extraordinary expressive power because meaningful parts can be assembled into more complex semantic structures. This partly underlies our ability to compose meanings into endlessly novel configurations, and sets us apart from other species and current computing devices. Crucially, human behaviour, including language use and linguistic data, indicates that composing parts into complex structures does not threaten the existence of constituent parts as independent units in the system: parts and wholes exist simultaneously yet independently from one another in the mind and brain. This independence is evident in human behaviour, but it seems at odds with what is known about the brain's exquisite sensitivity to statistical patterns: everyday language use is productive and expressive precisely because it can go beyond statistical regularities. Formal theories in philosophy and linguistics explain this fact by assuming that language and thought are compositional: systems of representations that separate a variable (or role) from its values (fillers), such that the meaning of a complex expression is a function of the values assigned to the variables. The debate on whether and how compositional systems could be implemented in minds, brains and machines remains vigorous. However, it has not yet resulted in mechanistic models of semantic composition: how, then, are the constituents of thoughts and sentences put and held together? We review and discuss current efforts at understanding this problem, and we chart possible routes for future research.

Abstract

I argue that cue integration, a psychophysiological mechanism from vision and multisensory perception, offers a computational linking hypothesis between psycholinguistic theory and neurobiological models of language. I propose that this mechanism, which incorporates probabilistic estimates of a cue's reliability, might function in language processing from the perception of a phoneme to the comprehension of a phrase structure. I briefly consider the implications of the cue integration hypothesis for an integrated theory of language that includes acquisition, production, dialogue and bilingualism, while grounding the hypothesis in canonical neural computation.

Abstract

Neither neurobiological nor process models of meaning composition specify the operator through which constituent parts are bound together into compositional structures. In this paper, we argue that a neurophysiological computation system cannot achieve the compositionality exhibited in human thought and language if it were to rely on a multiplicative operator to perform binding, as the tensor product (TP)-based systems that have been widely adopted in cognitive science, neuroscience and artificial intelligence do. We show via simulation and two behavioural experiments that TPs violate variable-value independence, but human behaviour does not. Specifically, TPs fail to capture that in the statements fuzzy cactus and fuzzy penguin, both cactus and penguin are predicated by fuzzy(x) and belong to the set of fuzzy things, rendering these arguments similar to each other. Consistent with that thesis, people judged arguments that shared the same role to be similar, even when those arguments themselves (e.g., cacti and penguins) were judged to be dissimilar when in isolation. By contrast, the similarity of the TPs representing fuzzy(cactus) and fuzzy(penguin) was determined by the similarity of the arguments, which in this case approaches zero. Based on these results, we argue that neural systems that use TPs for binding cannot approximate how the human mind and brain represent compositional information during processing. We describe a contrasting binding mechanism that any physiological or artificial neural system could use to maintain independence between a role and its argument, a prerequisite for compositionality and, thus, for instantiating the expressive power of human thought and language in a neural system.

Abstract

Humans learn to represent complex structures (e.g. natural language, music, mathematics) from experience with their environments. Often such structures are latent, hidden, or not encoded in statistics about sensory representations alone. Accounts of human cognition have long emphasized the importance of structured representations, yet the majority of contemporary neural networks do not learn structure from experience. Here, we describe one way that structured, functionally symbolic representations can be instantiated in an artificial neural network. Then, we describe how such latent structures (viz. predicates) can be learned from experience with unstructured data. Our approach exploits two principles from psychology and neuroscience: comparison of representations, and the naturally occurring dynamic properties of distributed computing across neuronal assemblies (viz. neural oscillations). We discuss how the ability to learn predicates from experience, to represent information compositionally, and to extrapolate knowledge to unseen data is core to understanding and modeling the most complex human behaviors (e.g. relational reasoning, analogy, language processing, game play).

Abstract

Active communication between researchers and society is necessary for the scientific community’s involvement in developing sciencebased
policies. This need is recognized by governmental and funding agencies that compel scientists to increase their public engagement
and disseminate research findings in an accessible fashion. Storytelling techniques can help convey science by engaging people’s imagination
and emotions. Yet, many researchers are uncertain about how to approach scientific storytelling, or feel they lack the tools to
undertake it. Here we explore some of the techniques intrinsic to crafting scientific narratives, as well as the reasons why scientific
storytellingmaybe an optimal way of communicating research to nonspecialists.Wealso point out current communication gaps between
science and society, particularly in the context of neurodiverse audiences and those that include neurological and psychiatric patients.
Present shortcomings may turn into areas of synergy with the potential to link neuroscience education, research, and advocacy

Abstract

Listeners are known to track statistical regularities in speech. Yet, which temporal cues
are encoded is unclear. This study tested effects of talker-specific habitual speech rate
and talker-independent average speech rate (heard over a longer period of time) on
the perception of the temporal Dutch vowel contrast /A/-/a:/. First, Experiment 1
replicated that slow local (surrounding) speech contexts induce fewer long /a:/
responses than faster contexts. Experiment 2 tested effects of long-term habitual
speech rate. One high-rate group listened to ambiguous vowels embedded in `neutral'
speech from talker A, intermixed with speech from fast talker B. Another low-rate group
listened to the same `neutral' speech from talker A, but to talker B being slow.
Between-group comparison of the `neutral' trials showed that the high-rate group
demonstrated a lower proportion of /a:/ responses, indicating that talker A's habitual
speech rate sounded slower when B was faster. In Experiment 3, both talkers
produced speech at both rates, removing the different habitual speech rates of talker A
and B, while maintaining the average rate differing between groups. This time no
global rate effect was observed. Taken together, the present experiments show that a
talker's habitual rate is encoded relative to the habitual rate of another talker, carrying
implications for episodic and constraint-based models of speech perception.

Abstract

Speech can be produced at different rates. Listeners take this rate variation into account by normalizing vowel duration for contextual speech rate: An ambiguous Dutch word /m?t/ is perceived as short /mAt/ when embedded in a slow context, but long /ma:t/ in a fast context. Whilst some have argued that this rate normalization involves low-level automatic perceptual processing, there is also evidence that it arises at higher-level cognitive processing stages, such as decision making. Prior research on rate-dependent speech perception has only used explicit recognition tasks to investigate the phenomenon, involving both perceptual processing and decision making. This study tested whether speech rate normalization can be observed without explicit decision making, using a cross-modal repetition priming paradigm. Results show that a fast precursor sentence makes an embedded ambiguous prime (/m?t/) sound (implicitly) more /a:/-like, facilitating lexical access to the long target word "maat" in a (explicit) lexical decision task. This result suggests that rate normalization is automatic, taking place even in the absence of an explicit recognition task. Thus, rate normalization is placed within the realm of everyday spoken conversation, where explicit categorization of ambiguous sounds is rare.

Abstract

The nature and the typological validity of the categories ‘realis’ and ‘irrealis’ has been a matter of intensive debate. In this paper we analyse the realis/irrealis dichotomy in Tundra Yukaghir (isolate, north-eastern Siberia), and show that in this language realis is associated with a meaningful contribution, namely, existential quantification over events. This contribution must be expressed overtly by a combination of syntactic and prosodic means. Irrealis is the default category: the clause is interpreted as irrealis in the absence of the marker of realis. This implies that the relevant typological question may turn out to be the semantics of realis, rather than irrealis. We further argue that the Tundra Yukaghir realis is a hybrid category composed of elements from different domains (information structure, lexical semantics, and quantification) unified at the level of interpretation via pragmatic enrichment. The concept of notional mood must therefore be expanded to include moods which come about in interpretation and do not constitute a discrete denotation.

Abstract

This study investigates the extent to which age-related language processing difficulties are due to a decline in sensory processes or to a deterioration of cognitive factors, specifically, attentional control. Two facets of attentional control were examined: inhibition of irrelevant information and divided attention. Younger and older adults were asked to categorize the initial phoneme of spoken syllables (“Was it m or n?”), trying to ignore the lexical status of the syllables. The phonemes were manipulated to range in eight steps from m to n. Participants also did a discrimination task on syllable pairs (“Were the initial sounds the same or different?”). Categorization and discrimination were performed under either divided attention (concurrent visual-search task) or focused attention (no visual task). The results showed that even when the younger and older adults were matched on their discrimination scores: (1) the older adults had more difficulty inhibiting lexical knowledge than did younger adults, (2) divided attention weakened lexical inhibition in both younger and older adults, and (3) divided attention impaired sound discrimination more in older than younger listeners. The results confirm the independent and combined contribution of sensory decline and deficit in attentional control to language processing difficulties associated with aging. The relative weight of these variables and their mechanisms of action are discussed in the context of theories of aging and language.

Abstract

he present study tested Japanese 4.5- and 10-month old infants' ability to discriminate three German vowel pairs, none of which are contrastive in Japanese, using a visual habituation–dishabituation paradigm. Japanese adults' discrimination of the same pairs was also tested. The results revealed that Japanese 4.5-month old infants discriminated the German /bu:k/-/by:k/ contrast, but they showed no evidence of discriminating the /bi:k/-/be:k/ or /bu:k/-/bo:k/ contrasts. Japanese 10-month old infants, on the other hand, discriminated the German /bi:k/-/be:k/ contrast, while they showed no evidence of discriminating the /bu:k/-/by:k/ or /bu:k/-/bo:k/ contrasts. Japanese adults, in contrast, were highly accurate in their discrimination of all of the pairs. The results indicate that discrimination of non-native contrasts is not always easy even for young infants, and that their ability to discriminate non-native contrasts can improve with age even when they receive no exposure to a language in which the given contrast is phonemic. © 2013 Wiley Periodicals, Inc. Dev Psychobiol 56: 192–209, 2014.

Abstract

Poor recognition of other-race faces is ubiquitous around the world. We resolve a longstanding contradiction in the literature concerning whether interracial social contact improves the other-race effect. For the first time, we measure the age at which contact was experienced. taking advantage of
unusual demographics allowing dissociation of childhood from adult contact, results show sufficient childhood contact eliminated poor other-race recognition altogether (confirming inter-country adoption
studies). Critically, however, the developmental window for easy acquisition of other-race faces closed by approximately 12 years of age and social contact as an adult — even over several years and involving many other-race friends — produced no improvement. Theoretically, this pattern of developmental change in plasticity mirrors that found in language, suggesting a shared origin grounded in the
functional importance of both skills to social communication. Practically, results imply that, where parents wish to ensure their offspring develop the perceptual skills needed to recognise other-race people easily, childhood experience should be encouraged: just as an English-speaking person who moves to France as a child (but not an adult) can easily become a native speaker of French, we can easily
become “native recognisers” of other-race faces via natural social exposure obtained in childhood, but not later

Abstract

This commentary on Gow and Olson [2015. Sentential influences on acoustic-phonetic processing: A Granger causality analysis of multimodal imaging data. Language, Cognition and Neuroscience. doi:10.1080/23273798.2015.1029498] questions in three ways their conclusion that speech perception is based on interactive processing. First, it is not clear that the data presented by Gow and Olson reflect normal speech recognition. Second, Gow and Olson's conclusion depends on still-debated assumptions about the functions performed by specific brain regions. Third, the results are compatible with feedforward models of speech perception and appear inconsistent with models in which there are online interactions about phonological content. We suggest that progress in the neuroscience of speech perception requires the generation of testable hypotheses about the function(s) performed by inter-regional connections

Abstract

Three cross-modal priming experiments examined the influence of pre-exposure to
pictures and printed words on the speed of spoken word recognition. Targets for
auditory lexical decision were spoken Dutch words and nonwords, presented in
isolation (Experiments 1 and 2) or after a short phrase (Experiment 3). Auditory
stimuli were preceded by primes which were pictures (Experiments 1 and 3) or those pictures’ printed names (Experiment 2). Prime-target pairs were phonologically onsetrelated (e.g., pijl-pijn, arrow-pain), were from the same semantic category (e.g., pijlzwaard, arrow-sword), or were unrelated on both dimensions. Phonological
interference and semantic facilitation were observed in all experiments. Priming
magnitude was similar for pictures and printed words, and did not vary with picture
viewing time or number of pictures in the display (either one or four). These effects
arose even though participants were not explicitly instructed to name the pictures and where strategic naming would interfere with lexical decision-making. This suggests
that, by default, processing of related pictures and printed words influences how
quickly we recognize related spoken words.