Publications

Displaying 501 - 600 of 667
  • Schreiweis, C., Bornschein, U., Burguière, E., Kerimoglu, C., Schreiter, S., Dannemann, M., Goyal, S., Rea, E., French, C. A., Puliyadi, R., Groszer, M., Fisher, S. E., Mundry, R., Winter, C., Hevers, W., Pääbo, S., Enard, W., & Graybiel, A. M. (2014). Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance. Proceedings of the National Academy of Sciences of the United States of America, 111, 14253-14258. doi:10.1073/pnas.1414542111.

    Abstract

    The acquisition of language and speech is uniquely human, but how genetic changes might have adapted the nervous system to this capacity is not well understood. Two human-specific amino acid substitutions in the transcription factor forkhead box P2 (FOXP2) are outstanding mechanistic candidates, as they could have been positively selected during human evolution and as FOXP2 is the sole gene to date firmly linked to speech and language development. When these two substitutions are introduced into the endogenous Foxp2 gene of mice (Foxp2hum), cortico-basal ganglia circuits are specifically affected. Here we demonstrate marked effects of this humanization of Foxp2 on learning and striatal neuroplasticity. Foxp2hum/hum mice learn stimulus–response associations faster than their WT littermates in situations in which declarative (i.e., place-based) and procedural (i.e., response-based) forms of learning could compete during transitions toward proceduralization of action sequences. Striatal districts known to be differently related to these two modes of learning are affected differently in the Foxp2hum/hum mice, as judged by measures of dopamine levels, gene expression patterns, and synaptic plasticity, including an NMDA receptor-dependent form of long-term depression. These findings raise the possibility that the humanized Foxp2 phenotype reflects a different tuning of corticostriatal systems involved in declarative and procedural learning, a capacity potentially contributing to adapting the human brain for speech and language acquisition.

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  • Segaert, K., Weber, K., Cladder-Micus, M., & Hagoort, P. (2014). The influence of verb-bound syntactic preferences on the processing of syntactic structures. Journal of Experimental Psychology: Learning, Memory, and Cognition, 40(5), 1448-1460. doi:10.1037/a0036796.

    Abstract

    Speakers sometimes repeat syntactic structures across sentences, a phenomenon called syntactic priming. We investigated the influence of verb-bound syntactic preferences on syntactic priming effects in response choices and response latencies for German ditransitive sentences. In the response choices we found inverse preference effects: There were stronger syntactic priming effects for primes in the less preferred structure, given the syntactic preference of the prime verb. In the response latencies we found positive preference effects: There were stronger syntactic priming effects for primes in the more preferred structure, given the syntactic preference of the prime verb. These findings provide further support for the idea that syntactic processing is lexically guided.
  • Senft, G. (1998). Body and mind in the Trobriand Islands. Ethos, 26, 73-104. doi:10.1525/eth.1998.26.1.73.

    Abstract

    This article discusses how the Trobriand Islanders speak about body and mind. It addresses the following questions: do the linguistic datafit into theories about lexical universals of body-part terminology? Can we make inferences about the Trobrianders' conceptualization of psychological and physical states on the basis of these data? If a Trobriand Islander sees these idioms as external manifestations of inner states, then can we interpret them as a kind of ethnopsychological theory about the body and its role for emotions, knowledge, thought, memory, and so on? Can these idioms be understood as representation of Trobriand ethnopsychological theory?
  • Senft, G., & Labov, W. (1978). Einige Prinzipien linguistischer Methodologie [transl. from English by Gunter Senft]. In N. Dittmar, & B. O. Rieck (Eds.), William Labov: Sprache im sozialen Kontext, vol. 2 (pp. 187-207). Königstein: Scriptor.
  • Senft, G. (1998). 'Noble Savages' and the 'Islands of Love': Trobriand Islanders in 'Popular Publications'. In J. Wassmann (Ed.), Pacific answers to Western hegemony: Cultural practices of identity construction (pp. 119-140). Oxford: Berg Publishers.
  • Senft, G. (1998). [Review of the book Anthropological linguistics: An introduction by William A. Foley]. Linguistics, 36, 995-1001.
  • Senft, G. (2005). Bronislaw Malinowski and linguistic pragmatics. In P. Cap (Ed.), Pragmatics today (pp. 139-155). Frankfurt am Main: Lang.
  • Senft, G. (2005). [Review of the book Malinowski: Odyssey of an anthropologist 1884-1920 by Michael Young]. Oceania, 75(3), 302-302.
  • Senft, G. (2005). [Review of the book The art of Kula by Shirley F. Campbell]. Anthropos, 100, 247-249.
  • Senft, G., & Labov, W. (1978). Hyperkorrektheit der unteren Mittelschicht als Faktor im Sprachwandel; [transl. from English by Gunter Senft]. In N. Dittmar, & B. O. Rieck (Eds.), William Labov: Sprache im sozialen Kontext, Vol.2 (pp. 129-146). Königstein: Scriptor.
  • Senft, G. (1998). Zeichenkonzeptionen in Ozeanien. In R. Posner, T. Robering, & T.. Sebeok (Eds.), Semiotics: A handbook on the sign-theoretic foundations of nature and culture (Vol. 2) (pp. 1971-1976). Berlin: de Gruyter.
  • Senghas, A., Ozyurek, A., & Kita, S. (2005). [Response to comment on Children creating core properties of language: Evidence from an emerging sign language in Nicaragua]. Science, 309(5731), 56c-56c. doi:10.1126/science.1110901.
  • Seuren, P. A. M. (2005). The origin of grammatical terminology. In B. Smelik, R. Hofman, C. Hamans, & D. Cram (Eds.), A companion in linguistics: A Festschrift for Anders Ahlqvist on the occasion of his sixtieth birthday (pp. 185-196). Nijmegen: Stichting Uitgeverij de Keltische Draak.
  • Seuren, P. A. M. (2005). The role of lexical data in semantics. In A. Cruse, F. Hundsnurscher, M. Job, & P. R. Lutzeier (Eds.), Lexikologie / Lexicology. Ein internationales Handbuch zur Natur und Struktur von Wörtern und Wortschätzen/An international handbook on the nature and structure of words and vocabularies. 2. Halbband / Volume 2 (pp. 1690-1696). Berlin: Walter de Gruyter.
  • Seuren, P. A. M. (1970). A note on descriptive adequacy. Journal of Linguistics, 6(2), 263-266. doi:10.1017/S0022226700002668.
  • Seuren, P. A. M. (1998). [Review of the book Adverbial subordination; A typology and history of adverbial subordinators based on European languages by Bernd Kortmann]. Cognitive Linguistics, 9(3), 317-319. doi:10.1515/cogl.1998.9.3.315.
  • Seuren, P. A. M. (1966). [Review of the book An introduction to morphology and syntax by Benjamin Elson and Velma Pickett]. Foundations of Language, 2(2), 213-217.
  • Seuren, P. A. M. (1979). [Review of the book Approaches to natural language ed. by K. Hintikka, J. Moravcsik and P. Suppes]. Leuvense Bijdragen, 68, 163-168.
  • Seuren, P. A. M. (1970). [Review of the book Betekenis en betekenisstructuur. Nagelaten geschriften van Prof. Dr. A. W. de Groot ed by G. F. Bos and H. Roose]. Foundations of Language, 6(2), 282-283.
  • Seuren, P. A. M. (1966). [Review of the book Grammar discovery procedures by Robert E. Longacre]. Foundations of Language, 2(2), 200-212.
  • Seuren, P. A. M. (1998). [Review of the book The Dutch pendulum: Linguistics in the Netherlands 1740-1900 by Jan Noordegraaf]. Bulletin of the Henry Sweet Society, 31, 46-50.
  • Seuren, P. A. M. (2005). Eubulides as a 20th-century semanticist. Language Sciences, 27(1), 75-95. doi:10.1016/j.langsci.2003.12.001.

    Abstract

    It is the purpose of the present paper to highlight the figure of Eubulides, a relatively unknown Greek philosopher who lived ±405–330 BC and taught at Megara, not far from Athens. He is mainly known for his four paradoxes (the Liar, the Sorites, the Electra, and the Horns), and for the mutual animosity between him and his younger contemporary Aristotle. The Megarian school of philosophy was one of the main sources of the great Stoic tradition in ancient philosophy. What has never been made explicit in the literature is the importance of the four paradoxes for the study of meaning in natural language: they summarize the whole research programme of 20th century formal or formally oriented semantics, including the problems of vague predicates (Sorites), intensional contexts (Electra), and presuppositions (Horns). One might say that modern formal or formally oriented semantics is essentially an attempt at finding linguistically tenable answers to problems arising in the context of Aristotelian thought. It is a surprising and highly significant fact that a contemporary of Aristotle already spotted the main weaknesses of the Aristotelian paradigm.
  • Seuren, P. A. M. (1979). Meer over minder dan hoeft. De Nieuwe Taalgids, 72(3), 236-239.
  • Seuren, P. A. M. (1963). Naar aanleiding van Dr. F. Balk-Smit Duyzentkunst "De Grammatische Functie". Levende Talen, 219, 179-186.
  • Seuren, P. A. M. (1978). Language and communication in primates. In D. J. Chivers, & J. Herbert (Eds.), Recent advances in primatology. Vol. 1: Behaviour (pp. 909-917). New York: Academic Press.
  • Seuren, P. A. M. (1978). Graadadjektieven en oriëntatie. Gramma, 2(1), 1-29.
  • Seuren, P. A. M. (1978). Grammar as an underground process. In A. Sinclair, R. J. Jarvella, & W. J. M. Levelt (Eds.), The child's conception of language (pp. 201-223). Berlin: Springer.
  • Seuren, P. A. M. (1966). Het probleem van de woorddefinitie. Tijdschrift voor Nederlandse Taal- en Letterkunde, 82(4), 259-293.
  • Seuren, P. A. M., & Jaspers, D. (2014). Logico-cognitive structure in the lexicon. Language, 90(3), 607-643. doi:10.1353/lan.2014.0058.

    Abstract

    This study is a prolegomenon to a formal theory of the natural growth of conceptual and lexical fields. Negation, in the various forms in which it occurs in language, is found to be a powerful indicator. Other than in standard logic, natural language negation selects its complement within universes of discourse that are, for practical and functional reasons, restricted in various ways and to different degrees. It is hypothesized that a system of cognitive principles drives recursive processes of universe restriction, which in turn affects logical relations within the restricted universes. This approach provides a new perspective in which to view the well-known clashes between standard logic and natural logical intuitions. Lexicalization in language, especially the morphological incorporation of negation, is limited to highly restricted universes, which explains, for example, why a dog can be said not to be a Catholic, but also not to be a non-Catholic. Cognition is taken to restrict the universe of discourse to contrary pairs, splitting up one or both of the contraries into further subuniverses as a result of further cognitive activity. It is shown how a logically sound square of opposition , expanded to a hexagon (Jacoby 1950, 1960, Sesmat 1951, Blanché 1952, 1953, 1966), is generated by a hierarchy of universe restrictions, defining the notion ‘natural’ for logical systems. The logical hexagon contains two additional vertices, one for ‘some but not all’ (the Y-type) and one for ‘either all or none’ (the U-type), and incorporates both the classic square and the Hamiltonian triangle of contraries . Some is thus considered semantically ambiguous, representing two distinct quantifiers. The pragmaticist claim that the language system contains only the standard logical ‘some perhaps all’ and that the ‘some but not all’ meaning is pragmatically derived from the use of the system is rejected. Four principles are proposed according to which negation selects a complement from the subuniverses at hand. On the basis of these principles and of the logico-cognitive system proposed, the well-known nonlexicalization not only of *nall and *nand but also of many other nonlogical cases found throughout the lexicons of languages is analyzed and explained
  • Seuren, P. A. M. (1998). Obituary. Herman Christiaan Wekker 1943–1997. Journal of Pidgin and Creole Languages, 13(1), 159-162.
  • Seuren, P. A. M. (2014). The cognitive ontogenesis of predicate logid. Notre Dame Journal of Formal Logic, 55, 499-532. doi:10.1215/00294527-2798718.

    Abstract

    Since Aristotle and the Stoa, there has been a clash, worsened by modern predicate logic, between logically defined operator meanings and natural intuitions. Pragmatics has tried to neutralize the clash by an appeal to the Gricean conversational maxims. The present study argues that the pragmatic attempt has been unsuccessful. The “softness” of the Gricean explanation fails to do justice to the robustness of the intuitions concerned, leaving the relation between the principles evoked and the observed facts opaque. Moreover, there are cases where the Gricean maxims fail to apply. A more adequate solution consists in the devising of a sound natural logic, part of the innate cognitive equipment of mankind. This account has proved successful in conjunction with a postulated cognitive mechanism in virtue of which the universe of discourse (Un) is stepwise and recursively restricted, so that the negation selects different complements according to the degree of restrictedness of Un. This mechanism explains not only the discrepancies between natural logical intuitions and known logical systems; it also accounts for certain systematic lexicalization gaps in the languages of the world. Finally, it is shown how stepwise restriction of Un produces the ontogenesis of natural predicate logic, while at the same time resolving the intuitive clashes with established logical systems that the Gricean maxims sought to explain
  • Seuren, P. A. M. (1979). Wat is semantiek? In B. Tervoort (Ed.), Wetenschap en taal: Een nieuwe reeks benaderingen van het verschijnsel taal (pp. 135-162). Muiderberg: Coutinho.
  • Seuren, P. A. M. (1998). Towards a discourse-semantic account of donkey anaphora. In S. Botley, & T. McEnery (Eds.), New Approaches to Discourse Anaphora: Proceedings of the Second Colloquium on Discourse Anaphora and Anaphor Resolution (DAARC2) (pp. 212-220). Lancaster: Universiy Centre for Computer Corpus Research on Language, Lancaster University.
  • Seuren, P. A. M. (2014). Universe restriction in the logic of language. In J. Hoeksema, & D. Gilbers (Eds.), Black Book: A Festschrift in Honor of Frans Zwarts (pp. 282-300). Groningen: University of Groningen.
  • Sha, L., Wu, X., Yao, Y., Wen, B., Feng, J., Sha, Z., Wang, X., Xing, X., Dou, W., Jin, L., Li, W., Wang, N., Shen, Y., Wang, J., Wu, L., & Xu, Q. (2014). Notch Signaling Activation Promotes Seizure Activity in Temporal Lobe Epilepsy. Molecular Neurobiology, 49(2), 633-644.

    Abstract

    Notch signaling in the nervous system is often regarded as a developmental pathway. However, recent studies have suggested that Notch is associated with neuronal discharges. Here, focusing on temporal lobe epilepsy, we found that Notch signaling was activated in the kainic acid (KA)-induced epilepsy model and in human epileptogenic tissues. Using an acute model of seizures, we showed that DAPT, an inhibitor of Notch, inhibited ictal activity. In contrast, pretreatment with exogenous Jagged1 to elevate Notch signaling before KA application had proconvulsant effects. In vivo, we demonstrated that the impacts of activated Notch signaling on seizures can in part be attributed to the regulatory role of Notch signaling on excitatory synaptic activity in CA1 pyramidal neurons. In vitro, we found that DAPT treatment impaired synaptic vesicle endocytosis in cultured hippocampal neurons. Taken together, our findings suggest a correlation between aberrant Notch signaling and epileptic seizures. Notch signaling is up-regulated in response to seizure activity, and its activation further promotes neuronal excitation of CA1 pyramidal neurons in acute seizures.
  • Shao, Z., Roelofs, A., Acheson, D. J., & Meyer, A. S. (2014). Electrophysiological evidence that inhibition supports lexical selection in picture naming. Brain Research, 1586, 130-142. doi:10.1016/j.brainres.2014.07.009.

    Abstract

    We investigated the neural basis of inhibitory control during lexical selection. Participants overtly named pictures while response times (RTs) and event-related brain potentials (ERPs) were recorded. The difficulty of lexical selection was manipulated by using object and action pictures with high name agreement (few response candidates) versus low name agreement (many response candidates). To assess the involvement of inhibition, we conducted delta plot analyses of naming RTs and examined the N2 component of the ERP. We found longer mean naming RTs and a larger N2 amplitude in the low relative to the high name agreement condition. For action naming we found a negative correlation between the slopes of the slowest delta segment and the difference in N2 amplitude between the low and high name agreement conditions. The converging behavioral and electrophysiological evidence suggests that selective inhibition is engaged to reduce competition during lexical selection in picture naming.
  • Shao, Z., Roelofs, A., & Meyer, A. S. (2014). Predicting naming latencies for action pictures: Dutch norms. Behavior Research Methods, 46, 274-283. doi:10.3758/s13428-013-0358-6.

    Abstract

    The present study provides Dutch norms for age of acquisition, familiarity, imageability, image agreement, visual complexity, word frequency, and word length (in syllables) for 124 line drawings of actions. Ratings were obtained from 117 Dutch participants. Word frequency was determined on the basis of the SUBTLEX-NL corpus (Keuleers, Brysbaert, & New, Behavior Research Methods, 42, 643–650, 2010). For 104 of the pictures, naming latencies and name agreement were determined in a separate naming experiment with 74 native speakers of Dutch. The Dutch norms closely corresponded to the norms for British English. Multiple regression analysis showed that age of acquisition, imageability, image agreement, visual complexity, and name agreement were significant predictors of naming latencies, whereas word frequency and word length were not. Combined with the results of a principal-component analysis, these findings suggest that variables influencing the processes of conceptual preparation and lexical selection affect latencies more strongly than do variables influencing word-form encoding.

    Additional information

    Shao_Behav_Res_2013_Suppl_Mat.doc
  • Shao, Z., Janse, E., Visser, K., & Meyer, A. S. (2014). What do verbal fluency tasks measure? Predictors of verbal fluency performance in older adults. Frontiers in Psychology, 5: 772. doi:10.3389/fpsyg.2014.00772.

    Abstract

    This study examined the contributions of verbal ability and executive control to verbal fluency performance in older adults (n=82). Verbal fluency was assessed in letter and category fluency tasks, and performance on these tasks was related to indicators of vocabulary size, lexical access speed, updating, and inhibition ability. In regression analyses the number of words produced in both fluency tasks was predicted by updating ability, and the speed of the first response was predicted by vocabulary size and, for category fluency only, lexical access speed. These results highlight the hybrid character of both fluency tasks, which may limit their usefulness for research and clinical purposes.
  • Shapiro, K. A., Mottaghy, F. M., Schiller, N. O., Poeppel, T. D., Flüss, M. O., Müller, H. W., Caramazza, A., & Krause, B. J. (2005). Dissociating neural correlates for nouns and verbs. NeuroImage, 24(4), 1058-1067. doi:10.1016/j.neuroimage.2004.10.015.

    Abstract

    Dissociations in the ability to produce words of different grammatical categories are well established in neuropsychology but have not been corroborated fully with evidence from brain imaging. Here we report on a PET study designed to reveal the anatomical correlates of grammatical processes involving nouns and verbs. German-speaking subjects were asked to produce either plural and singular nouns, or first-person plural and singular verbs. Verbs, relative to nouns, activated a left frontal cortical network, while the opposite contrast (nouns–verbs) showed greater activation in temporal regions bilaterally. Similar patterns emerged when subjects performed the task with pseudowords used as nouns or as verbs. These results converge with findings from lesion studies and suggest that grammatical category is an important dimension of organization for knowledge of language in the brain.
  • Sharp, D. J., Scott, S. K., Cutler, A., & Wise, R. J. S. (2005). Lexical retrieval constrained by sound structure: The role of the left inferior frontal gyrus. Brain and Language, 92(3), 309-319. doi:10.1016/j.bandl.2004.07.002.

    Abstract

    Positron emission tomography was used to investigate two competing hypotheses about the role of the left inferior frontal gyrus (IFG) in word generation. One proposes a domain-specific organization, with neural activation dependent on the type of information being processed, i.e., surface sound structure or semantic. The other proposes a process-specific organization, with activation dependent on processing demands, such as the amount of selection needed to decide between competing lexical alternatives. In a novel word retrieval task, word reconstruction (WR), subjects generated real words from heard non-words by the substitution of either a vowel or consonant. Both types of lexical retrieval, informed by sound structure alone, produced activation within anterior and posterior left IFG regions. Within these regions there was greater activity for consonant WR, which is more difficult and imposes greater processing demands. These results support a process-specific organization of the anterior left IFG.
  • Shayan, S., Ozturk, O., Bowerman, M., & Majid, A. (2014). Spatial metaphor in language can promote the development of cross-modal mappings in children. Developmental Science, 17(4), 636-643. doi:10.1111/desc.12157.

    Abstract

    Pitch is often described metaphorically: for example, Farsi and Turkish speakers use a ‘thickness’ metaphor (low sounds are ‘thick’ and high sounds are ‘thin’), while German and English speakers use a height metaphor (‘low’, ‘high’). This study examines how child and adult speakers of Farsi, Turkish, and German map pitch and thickness using a cross-modal association task. All groups, except for German children, performed significantly better than chance. German-speaking adults’ success suggests the pitch-to-thickness association can be learned by experience. But the fact that German children were at chance indicates that this learning takes time. Intriguingly, Farsi and Turkish children's performance suggests that learning cross-modal associations can be boosted through experience with consistent metaphorical mappings in the input language
  • Shkaravska, O., & Van Eekelen, M. (2014). Univariate polynomial solutions of algebraic difference equations. Journal of Symbolic Computation, 60, 15-28. doi:10.1016/j.jsc.2013.10.010.

    Abstract

    Contrary to linear difference equations, there is no general theory of difference equations of the form G(P(x−τ1),…,P(x−τs))+G0(x)=0, with τi∈K, G(x1,…,xs)∈K[x1,…,xs] of total degree D⩾2 and G0(x)∈K[x], where K is a field of characteristic zero. This article is concerned with the following problem: given τi, G and G0, find an upper bound on the degree d of a polynomial solution P(x), if it exists. In the presented approach the problem is reduced to constructing a univariate polynomial for which d is a root. The authors formulate a sufficient condition under which such a polynomial exists. Using this condition, they give an effective bound on d, for instance, for all difference equations of the form G(P(x−a),P(x−a−1),P(x−a−2))+G0(x)=0 with quadratic G, and all difference equations of the form G(P(x),P(x−τ))+G0(x)=0 with G having an arbitrary degree.
  • Sidnell, J., & Enfield, N. J. (2014). Deixis and the interactional foundations of reference. In Y. Huang (Ed.), The Oxford handbook of pragmatics.
  • Sidnell, J., Kockelman, P., & Enfield, N. J. (2014). Community and social life. In N. J. Enfield, P. Kockelman, & J. Sidnell (Eds.), The Cambridge handbook of linguistic anthropology (pp. 481-483). Cambridge: Cambridge University Press.
  • Sidnell, J., Enfield, N. J., & Kockelman, P. (2014). Interaction and intersubjectivity. In N. J. Enfield, P. Kockelman, & J. Sidnell (Eds.), The Cambridge handbook of linguistic anthropology (pp. 343-345). Cambridge: Cambridge University Press.
  • Sidnell, J., & Enfield, N. J. (2014). The ontology of action, in interaction. In N. J. Enfield, P. Kockelman, & J. Sidnell (Eds.), The Cambridge handbook of linguistic anthropology (pp. 423-446). Cambridge: Cambridge University Press.
  • Silva, S., Branco, P., Barbosa, F., Marques-Teixeira, J., Petersson, K. M., & Castro, S. L. (2014). Musical phrase boundaries, wrap-up and the closure positive shift. Brain Research, 1585, 99-107. doi:10.1016/j.brainres.2014.08.025.

    Abstract

    We investigated global integration (wrap-up) processes at the boundaries of musical phrases by comparing the effects of well and non-well formed phrases on event-related potentials time-locked to two boundary points: the onset and the offset of the boundary pause. The Closure Positive Shift, which is elicited at the boundary offset, was not modulated by the quality of phrase structure (well vs. non-well formed). In contrast, the boundary onset potentials showed different patterns for well and non-well formed phrases. Our results contribute to specify the functional meaning of the Closure Positive Shift in music, shed light on the large-scale structural integration of musical input, and raise new hypotheses concerning shared resources between music and language.
  • Silva, S., Barbosa, F., Marques-Teixeira, J., Petersson, K. M., & Castro, S. L. (2014). You know when: Event-related potentials and theta/beat power indicate boundary prediction in music. Journal of Integrative Neuroscience, 13(1), 19-34. doi:10.1142/S0219635214500022.

    Abstract

    Neuroscientific and musicological approaches to music cognition indicate that listeners familiarized in the Western tonal tradition expect a musical phrase boundary at predictable time intervals. However, phrase boundary prediction processes in music remain untested. We analyzed event-related potentials (ERPs) and event-related induced power changes at the onset and offset of a boundary pause. We made comparisons with modified melodies, where the pause was omitted and filled by tones. The offset of the pause elicited a closure positive shift (CPS), indexing phrase boundary detection. The onset of the filling tones elicited significant increases in theta and beta powers. In addition, the P2 component was larger when the filling tones started than when they ended. The responses to boundary omission suggest that listeners expected to hear a boundary pause. Therefore, boundary prediction seems to coexist with boundary detection in music segmentation.
  • Simanova, I., Hagoort, P., Oostenveld, R., & Van Gerven, M. A. J. (2014). Modality-independent decoding of semantic information from the human brain. Cerebral Cortex, 24, 426-434. doi:10.1093/cercor/bhs324.

    Abstract

    An ability to decode semantic information from fMRI spatial patterns has been demonstrated in previous studies mostly for 1 specific input modality. In this study, we aimed to decode semantic category independent of the modality in which an object was presented. Using a searchlight method, we were able to predict the stimulus category from the data while participants performed a semantic categorization task with 4 stimulus modalities (spoken and written names, photographs, and natural sounds). Significant classification performance was achieved in all 4 modalities. Modality-independent decoding was implemented by training and testing the searchlight method across modalities. This allowed the localization of those brain regions, which correctly discriminated between the categories, independent of stimulus modality. The analysis revealed large clusters of voxels in the left inferior temporal cortex and in frontal regions. These voxels also allowed category discrimination in a free recall session where subjects recalled the objects in the absence of external stimuli. The results show that semantic information can be decoded from the fMRI signal independently of the input modality and have clear implications for understanding the functional mechanisms of semantic memory.
  • Simon, E., & Sjerps, M. J. (2014). Developing non-native vowel representations: a study on child second language acquisition. COPAL: Concordia Working Papers in Applied Linguistics, 5, 693-708.

    Abstract

    This study examines what stage 9‐12‐year‐old Dutch‐speaking children have reached in the development of their L2 lexicon, focusing on its phonological specificity. Two experiments were carried out with a group of Dutch‐speaking children and adults learning English. In a first task, listeners were asked to judge Dutch words which were presented with either the target Dutch vowel or with an English vowel synthetically inserted. The second experiment was a mirror of the first, i.e. with English words and English or Dutch vowels inserted. It was examined to what extent the listeners accepted substitutions of Dutch vowels by English ones, and vice versa. The results of the experiments suggest that the children have not reached the same degree of phonological specificity of L2 words as the adults. Children not only experience a strong influence of their native vowel categories when listening to L2 words, they also apply less strict criteria.
  • Simon, E., Sjerps, M. J., & Fikkert, P. (2014). Phonological representations in children’s native and non-native lexicon. Bilingualism: Language and Cognition, 17(1), 3-21. doi:10.1017/S1366728912000764.

    Abstract

    This study investigated the phonological representations of vowels in children's native and non-native lexicons. Two experiments were mispronunciation tasks (i.e., a vowel in words was substituted by another vowel from the same language). These were carried out by Dutch-speaking 9–12-year-old children and Dutch-speaking adults, in their native (Experiment 1, Dutch) and non-native (Experiment 2, English) language. A third experiment tested vowel discrimination. In Dutch, both children and adults could accurately detect mispronunciations. In English, adults, and especially children, detected substitutions of native vowels (i.e., vowels that are present in the Dutch inventory) by non-native vowels more easily than changes in the opposite direction. Experiment 3 revealed that children could accurately discriminate most of the vowels. The results indicate that children's L1 categories strongly influenced their perception of English words. However, the data also reveal a hint of the development of L2 phoneme categories.

    Additional information

    Simon_SuppMaterial.pdf
  • Simpson, N. H., Addis, L., Brandler, W. M., Slonims, V., Clark, A., Watson, J., Scerri, T. S., Hennessy, E. R., Stein, J., Talcott, J., Conti-Ramsden, G., O'Hare, A., Baird, G., Fairfax, B. P., Knight, J. C., Paracchini, S., Fisher, S. E., Newbury, D. F., & The SLI Consortium (2014). Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia. Developmental Medicine and Child Neurology, 56, 346-353. doi:10.1111/dmcn.12294.

    Abstract

    Aim Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex chromosome aneuploidies in individuals with language impairment or dyslexia. Method Genome-wide single nucleotide polymorphism genotyping was performed in three sample sets: a clinical cohort of individuals with speech and language deficits (87 probands: 61 males, 26 females; age range 4 to 23 years), a replication cohort of individuals with SLI, from both clinical and epidemiological samples (209 probands: 139 males, 70 females; age range 4 to 17 years), and a set of individuals with dyslexia (314 probands: 224 males, 90 females; age range 7 to 18 years). Results In the clinical language-impaired cohort, three abnormal karyotypic results were identified in probands (proband yield 3.4%). In the SLI replication cohort, six abnormalities were identified providing a consistent proband yield (2.9%). In the sample of individuals with dyslexia, two sex chromosome aneuploidies were found giving a lower proband yield of 0.6%. In total, two XYY, four XXY (Klinefelter syndrome), three XXX, one XO (Turner syndrome), and one unresolved karyotype were identified. Interpretation The frequency of sex chromosome aneuploidies within each of the three cohorts was increased over the expected population frequency (approximately 0.25%) suggesting that genetic testing may prove worthwhile for individuals with language and literacy problems and normal non-verbal IQ. Early detection of these aneuploidies can provide information and direct the appropriate management for individuals.
  • Slobin, D. I., Ibarretxe-Antuñano, I., Kopecka, A., & Majid, A. (2014). Manners of human gait: A crosslinguistic event-naming study. Cognitive Linguistics, 25, 701-741. doi:10.1515/cog-2014-0061.

    Abstract

    Crosslinguistic studies of expressions of motion events have found that Talmy's binary typology of verb-framed and satellite-framed languages is reflected in language use. In particular, Manner of motion is relatively more elaborated in satellite-framed languages (e.g., in narrative, picture description, conversation, translation). The present research builds on previous controlled studies of the domain of human motion by eliciting descriptions of a wide range of manners of walking and running filmed in natural circumstances. Descriptions were elicited from speakers of two satellite-framed languages (English, Polish) and three verb-framed languages (French, Spanish, Basque). The sampling of events in this study resulted in four major semantic clusters for these five languages: walking, running, non-canonical gaits (divided into bounce-and-recoil and syncopated movements), and quadrupedal movement (crawling). Counts of verb types found a broad tendency for satellite-framed languages to show greater lexical diversity, along with substantial within group variation. Going beyond most earlier studies, we also examined extended descriptions of manner of movement, isolating types of manner. The following categories of manner were identified and compared: attitude of actor, rate, effort, posture, and motor patterns of legs and feet. Satellite-framed speakers tended to elaborate expressive manner verbs, whereas verb-framed speakers used modification to add manner to neutral motion verbs
  • Sloetjes, H. (2014). ELAN: Multimedia annotation application. In J. Durand, U. Gut, & G. Kristoffersen (Eds.), The Oxford Handbook of Corpus Phonology (pp. 305-320). Oxford: Oxford University Press.
  • Smeets, C. J. L. M., & Verbeek, D. (2014). Review Cerebellar ataxia and functional genomics: Identifying the routes to cerebellar neurodegeneration. Biochimica et Biophysica Acta: BBA, 1842(10), 2030-2038. doi:10.1016/j.bbadis.2014.04.004.

    Abstract

    Cerebellar ataxias are progressive neurodegenerative disorders characterized by atrophy of the cerebellum leading to motor dysfunction, balance problems, and limb and gait ataxia. These include among others, the dominantly inherited spinocerebellar ataxias, recessive cerebellar ataxias such as Friedreich's ataxia, and X-linked cerebellar ataxias. Since all cerebellar ataxias display considerable overlap in their disease phenotypes, common pathological pathways must underlie the selective cerebellar neurodegeneration. Therefore, it is important to identify the molecular mechanisms and routes to neurodegeneration that cause cerebellar ataxia. In this review, we discuss the use of functional genomic approaches including whole-exome sequencing, genome-wide gene expression profiling, miRNA profiling, epigenetic profiling, and genetic modifier screens to reveal the underlying pathogenesis of various cerebellar ataxias. These approaches have resulted in the identification of many disease genes, modifier genes, and biomarkers correlating with specific stages of the disease. This article is part of a Special Issue entitled: From Genome to Function.
  • Smith, A. C., Monaghan, P., & Huettig, F. (2014). Modelling language – vision interactions in the hub and spoke framework. In J. Mayor, & P. Gomez (Eds.), Computational Models of Cognitive Processes: Proceedings of the 13th Neural Computation and Psychology Workshop (NCPW13). (pp. 3-16). Singapore: World Scientific Publishing.

    Abstract

    Multimodal integration is a central characteristic of human cognition. However our understanding of the interaction between modalities and its influence on behaviour is still in its infancy. This paper examines the value of the Hub & Spoke framework (Plaut, 2002; Rogers et al., 2004; Dilkina et al., 2008; 2010) as a tool for exploring multimodal interaction in cognition. We present a Hub and Spoke model of language–vision information interaction and report the model’s ability to replicate a range of phonological, visual and semantic similarity word-level effects reported in the Visual World Paradigm (Cooper, 1974; Tanenhaus et al, 1995). The model provides an explicit connection between the percepts of language and the distribution of eye gaze and demonstrates the scope of the Hub-and-Spoke architectural framework by modelling new aspects of multimodal cognition.
  • Smith, A. C., Monaghan, P., & Huettig, F. (2014). Literacy effects on language and vision: Emergent effects from an amodal shared resource (ASR) computational model. Cognitive Psychology, 75, 28-54. doi:10.1016/j.cogpsych.2014.07.002.

    Abstract

    Learning to read and write requires an individual to connect additional orthographic representations to pre-existing mappings between phonological and semantic representations of words. Past empirical results suggest that the process of learning to read and write (at least in alphabetic languages) elicits changes in the language processing system, by either increasing the cognitive efficiency of mapping between representations associated with a word, or by changing the granularity of phonological processing of spoken language, or through a combination of both. Behavioural effects of literacy have typically been assessed in offline explicit tasks that have addressed only phonological processing. However, a recent eye tracking study compared high and low literate participants on effects of phonology and semantics in processing measured implicitly using eye movements. High literates’ eye movements were more affected by phonological overlap in online speech than low literates, with only subtle differences observed in semantics. We determined whether these effects were due to cognitive efficiency and/or granularity of speech processing in a multimodal model of speech processing – the amodal shared resource model (ASR, Smith, Monaghan, & Huettig, 2013). We found that cognitive efficiency in the model had only a marginal effect on semantic processing and did not affect performance for phonological processing, whereas fine-grained versus coarse-grained phonological representations in the model simulated the high/low literacy effects on phonological processing, suggesting that literacy has a focused effect in changing the grain-size of phonological mappings.
  • Smits, R. (1998). A model for dependencies in phonetic categorization. Proceedings of the 16th International Congress on Acoustics and the 135th Meeting of the Acoustical Society of America, 2005-2006.

    Abstract

    A quantitative model of human categorization behavior is proposed, which can be applied to 4-alternative forced-choice categorization data involving two binary classifications. A number of processing dependencies between the two classifications are explicitly formulated, such as the dependence of the location, orientation, and steepness of the class boundary for one classification on the outcome of the other classification. The significance of various types of dependencies can be tested statistically. Analyses of a data set from the literature shows that interesting dependencies in human speech recognition can be uncovered using the model.
  • Spada, D., Verga, L., Iadanza, A., Tettamanti, M., & Perani, D. (2014). The auditory scene: An fMRI study on melody and accompaniment in professional pianists. NeuroImage, 102(2), 764-775. doi:10.1016/j.neuroimage.2014.08.036.

    Abstract

    The auditory scene is a mental representation of individual sounds extracted from the summed sound waveform reaching the ears of the listeners. Musical contexts represent particularly complex cases of auditory scenes. In such a scenario, melody may be seen as the main object moving on a background represented by the accompaniment. Both melody and accompaniment vary in time according to harmonic rules, forming a typical texture with melody in the most prominent, salient voice. In the present sparse acquisition functional magnetic resonance imaging study, we investigated the interplay between melody and accompaniment in trained pianists, by observing the activation responses elicited by processing: (1) melody placed in the upper and lower texture voices, leading to, respectively, a higher and lower auditory salience; (2) harmonic violations occurring in either the melody, the accompaniment, or both. The results indicated that the neural activation elicited by the processing of polyphonic compositions in expert musicians depends upon the upper versus lower position of the melodic line in the texture, and showed an overall greater activation for the harmonic processing of melody over accompaniment. Both these two predominant effects were characterized by the involvement of the posterior cingulate cortex and precuneus, among other associative brain regions. We discuss the prominent role of the posterior medial cortex in the processing of melodic and harmonic information in the auditory stream, and propose to frame this processing in relation to the cognitive construction of complex multimodal sensory imagery scenes.
  • Srivastava, S., Budwig, N., & Narasimhan, B. (2005). A developmental-functionalist view of the development of transitive and intratransitive constructions in a Hindi-speaking child: A case study. International Journal of Idiographic Science, 2.
  • Stassen, H., & Levelt, W. J. M. (1979). Systems, automata, and grammars. In J. Michon, E. Eijkman, & L. De Klerk (Eds.), Handbook of psychonomics: Vol. 1 (pp. 187-243). Amsterdam: North Holland.
  • Stergiakouli, E., Gaillard, R., Tavaré, J. M., Balthasar, N., Loos, R. J., Taal, H. R., Evans, D. M., Rivadeneira, F., St Pourcain, B., Uitterlinden, A. G., Kemp, J. P., Hofman, A., Ring, S. M., Cole, T. J., Jaddoe, V. W. V., Davey Smith, G., & Timpson, N. J. (2014). Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity, 22(10), 2252-2259. doi:10.1002/oby.20840.

    Abstract

    OBJECTIVE: Genome-wide association studies (GWAS) of BMI are mostly undertaken under the assumption that "kg/m(2) " is an index of weight fully adjusted for height, but in general this is not true. The aim here was to assess the contribution of common genetic variation to a adjusted version of that phenotype which appropriately accounts for covariation in height in children. METHODS: A GWAS of height-adjusted BMI (BMI[x] = weight/height(x) ), calculated to be uncorrelated with height, in 5809 participants (mean age 9.9 years) from the Avon Longitudinal Study of Parents and Children (ALSPAC) was performed. RESULTS: GWAS based on BMI[x] yielded marked differences in genomewide results profile. SNPs in ADCY3 (adenylate cyclase 3) were associated at genome-wide significance level (rs11676272 (0.28 kg/m(3.1) change per allele G (0.19, 0.38), P = 6 × 10(-9) ). In contrast, they showed marginal evidence of association with conventional BMI [rs11676272 (0.25 kg/m(2) (0.15, 0.35), P = 6 × 10(-7) )]. Results were replicated in an independent sample, the Generation R study. CONCLUSIONS: Analysis of BMI[x] showed differences to that of conventional BMI. The association signal at ADCY3 appeared to be driven by a missense variant and it was strongly correlated with expression of this gene. Our work highlights the importance of well understood phenotype use (and the danger of convention) in characterising genetic contributions to complex traits.

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  • Stine-Morrow, E., Payne, B., Roberts, B., Kramer, A., Morrow, D., Payne, L., Hill, P., Jackson, J., Gao, X., Noh, S., Janke, M., & Parisi, J. (2014). Training versus engagement as paths to cognitive enrichment with aging. Psychology and Aging, 29, 891-906. doi:10.1037/a0038244.

    Abstract

    While a training model of cognitive intervention targets the improvement of particular skills through instruction and practice, an engagement model is based on the idea that being embedded in an intellectually and socially complex environment can impact cognition, perhaps even broadly, without explicit instruction. We contrasted these 2 models of cognitive enrichment by randomly assigning healthy older adults to a home-based inductive reasoning training program, a team-based competitive program in creative problem solving, or a wait-list control. As predicted, those in the training condition showed selective improvement in inductive reasoning. Those in the engagement condition, on the other hand, showed selective improvement in divergent thinking, a key ability exercised in creative problem solving. On average, then, both groups appeared to show ability-specific effects. However, moderators of change differed somewhat for those in the engagement and training interventions. Generally, those who started either intervention with a more positive cognitive profile showed more cognitive growth, suggesting that cognitive resources enabled individuals to take advantage of environmental enrichment. Only in the engagement condition did initial levels of openness and social network size moderate intervention effects on cognition, suggesting that comfort with novelty and an ability to manage social resources may be additional factors contributing to the capacity to take advantage of the environmental complexity associated with engagement. Collectively, these findings suggest that training and engagement models may offer alternative routes to cognitive resilience in late life

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  • Stivers, T. (2005). Parent resistance to physicians' treatment recommendations: One resource for initiating a negotiation of the treatment decision. Health Communication, 18(1), 41-74. doi:10.1207/s15327027hc1801_3.

    Abstract

    This article examines pediatrician-parent interaction in the context of acute pediatric encounters for children with upper respiratory infections. Parents and physicians orient to treatment recommendations as normatively requiring parent acceptance for physicians to close the activity. Through acceptance, withholding of acceptance, or active resistance, parents have resources with which to negotiate for a treatment outcome that is in line with their own wants. This article offers evidence that even in acute care, shared decision making not only occurs but, through normative constraints, is mandated for parents and physicians to reach accord in the treatment decision.
  • Stivers, T. (2005). Modified repeats: One method for asserting primary rights from second position. Research on Language and Social Interaction, 38(2), 131-158. doi:10.1207/s15327973rlsi3802_1.

    Abstract

    In this article I examine one practice speakers have for confirming when confirmation was not otherwise relevant. The practice involves a speaker repeating an assertion previously made by another speaker in modified form with stress on the copula/auxiliary. I argue that these modified repeats work to undermine the first speaker's default ownership and rights over the claim and instead assert the primacy of the second speaker's rights to make the statement. Two types of modified repeats are identified: partial and full. Although both involve competing for primacy of the claim, they occur in distinct sequential environments: The former are generally positioned after a first claim was epistemically downgraded, whereas the latter are positioned following initial claims that were offered straightforwardly, without downgrading.
  • Stivers, T., & Sidnell, J. (2005). Introduction: Multimodal interaction. Semiotica, 156(1/4), 1-20. doi:10.1515/semi.2005.2005.156.1.

    Abstract

    That human social interaction involves the intertwined cooperation of different modalities is uncontroversial. Researchers in several allied fields have, however, only recently begun to document the precise ways in which talk, gesture, gaze, and aspects of the material surround are brought together to form coherent courses of action. The papers in this volume are attempts to develop this line of inquiry. Although the authors draw on a range of analytic, theoretical, and methodological traditions (conversation analysis, ethnography, distributed cognition, and workplace studies), all are concerned to explore and illuminate the inherently multimodal character of social interaction. Recent studies, including those collected in this volume, suggest that different modalities work together not only to elaborate the semantic content of talk but also to constitute coherent courses of action. In this introduction we present evidence for this position. We begin by reviewing some select literature focusing primarily on communicative functions and interactive organizations of specific modalities before turning to consider the integration of distinct modalities in interaction.
  • Stivers, T. (2005). Non-antibiotic treatment recommendations: Delivery formats and implications for parent resistance. Social Science & Medicine, 60(5), 949-964. doi:10.1016/j.socscimed.2004.06.040.

    Abstract

    This study draws on a database of 570 community-based acute pediatric encounters in the USA and uses conversation analysis as a methodology to identify two formats physicians use to recommend non-antibiotic treatment in acute pediatric care (using a subset of 309 cases): recommendations for particular treatment (e.g., “I’m gonna give her some cough medicine.”) and recommendations against particular treatment (e.g., “She doesn’t need any antibiotics.”). The findings are that the presentation of a specific affirmative recommendation for treatment is less likely to engender parent resistance to a non-antibiotic treatment recommendation than a recommendation against particular treatment even if the physician later offers a recommendation for particular treatment. It is suggested that physicians who provide a specific positive treatment recommendation followed by a negative recommendation are most likely to attain parent alignment and acceptance when recommending a non-antibiotic treatment for a viral upper respiratory illness.
  • Stivers, T. (1998). Prediagnostic commentary in veterinarian-client interaction. Research on Language and Social Interaction, 31(2), 241-277. doi:10.1207/s15327973rlsi3102_4.
  • Stolk, A., Noordzij, M. L., Verhagen, L., Volman, I., Schoffelen, J.-M., Oostenveld, R., Hagoort, P., & Toni, I. (2014). Cerebral coherence between communicators marks the emergence of meaning. Proceedings of the National Academy of Sciences of the United States of America, 111, 18183-18188. doi:10.1073/pnas.1414886111.

    Abstract

    How can we understand each other during communicative interactions? An influential suggestion holds that communicators are primed by each other’s behaviors, with associative mechanisms automatically coordinating the production of communicative signals and the comprehension of their meanings. An alternative suggestion posits that mutual understanding requires shared conceptualizations of a signal’s use, i.e., “conceptual pacts” that are abstracted away from specific experiences. Both accounts predict coherent neural dynamics across communicators, aligned either to the occurrence of a signal or to the dynamics of conceptual pacts. Using coherence spectral-density analysis of cerebral activity simultaneously measured in pairs of communicators, this study shows that establishing mutual understanding of novel signals synchronizes cerebral dynamics across communicators’ right temporal lobes. This interpersonal cerebral coherence occurred only within pairs with a shared communicative history, and at temporal scales independent from signals’ occurrences. These findings favor the notion that meaning emerges from shared conceptualizations of a signal’s use.
  • Stolk, A., Noordzij, M. L., Volman, I., Verhagen, L., Overeem, S., van Elswijk, G., Bloem, B., Hagoort, P., & Toni, I. (2014). Understanding communicative actions: A repetitive TMS study. Cortex, 51, 25-34. doi:10.1016/j.cortex.2013.10.005.

    Abstract

    Despite the ambiguity inherent in human communication, people are remarkably efficient in establishing mutual understanding. Studying how people communicate in novel settings provides a window into the mechanisms supporting the human competence to rapidly generate and understand novel shared symbols, a fundamental property of human communication. Previous work indicates that the right posterior superior temporal sulcus (pSTS) is involved when people understand the intended meaning of novel communicative actions. Here, we set out to test whether normal functioning of this cerebral structure is required for understanding novel communicative actions using inhibitory low-frequency repetitive transcranial magnetic stimulation (rTMS). A factorial experimental design contrasted two tightly matched stimulation sites (right pSTS vs. left MT+, i.e. a contiguous homotopic task-relevant region) and tasks (a communicative task vs. a visual tracking task that used the same sequences of stimuli). Overall task performance was not affected by rTMS, whereas changes in task performance over time were disrupted according to TMS site and task combinations. Namely, rTMS over pSTS led to a diminished ability to improve action understanding on the basis of recent communicative history, while rTMS over MT+ perturbed improvement in visual tracking over trials. These findings qualify the contributions of the right pSTS to human communicative abilities, showing that this region might be necessary for incorporating previous knowledge, accumulated during interactions with a communicative partner, to constrain the inferential process that leads to action understanding.
  • Stolker, C. J. J. M., & Poletiek, F. H. (1998). Smartengeld - Wat zijn we eigenlijk aan het doen? Naar een juridische en psychologische evaluatie. In F. Stadermann (Ed.), Bewijs en letselschade (pp. 71-86). Lelystad, The Netherlands: Koninklijke Vermande.
  • Striano, T., & Liszkowski, U. (2005). Sensitivity to the context of facial expression in the still face at 3-, 6-, and 9-months of age. Infant Behavior and Development, 28(1), 10-19. doi:10.1016/j.infbeh.2004.06.004.

    Abstract

    Thirty-eight 3-, 6-, and 9-month-old infants interacted in a face to face situation with a female stranger who disrupted the on-going interaction with 30 s Happy and Neutral still face episodes. Three- and 6-month-olds manifested a robust still face response for gazing and smiling. For smiling, 9-month-olds manifested a floor effect such that no still face effect could be shown. For gazing, 9-month-olds' still face response was modulated by the context of interaction such that it was less pronounced if a happy still face was presented first. The findings point to a developmental transition by the end of the first year, whereby infants' still face response becomes increasingly influenced by the context of social interaction. (C) 2004 Published by Elsevier Inc. [References: 35]
  • Suppes, P., Böttner, M., & Liang, L. (1998). Machine Learning of Physics Word Problems: A Preliminary Report. In A. Aliseda, R. van Glabbeek, & D. Westerståhl (Eds.), Computing Natural Language (pp. 141-154). Stanford, CA, USA: CSLI Publications.
  • Swaab, T. Y., Brown, C. M., & Hagoort, P. (1998). Understanding ambiguous words in sentence contexts: Electrophysiological evidence for delayed contextual selection in Broca's aphasia. Neuropsychologia, 36(8), 737-761. doi:10.1016/S0028-3932(97)00174-7.

    Abstract

    This study investigates whether spoken sentence comprehension deficits in Broca's aphasics results from their inability to access the subordinate meaning of ambiguous words (e.g. bank), or alternatively, from a delay in their selection of the contextually appropriate meaning. Twelve Broca's aphasics and twelve elderly controls were presented with lexical ambiguities in three context conditions, each followed by the same target words. In the concordant condition, the sentence context biased the meaning of the sentence final ambiguous word that was related to the target. In the discordant condition, the sentence context biased the meaning of the sentence final ambiguous word that was incompatible with the target.In the unrelated condition, the sentence-final word was unambiguous and unrelated to the target. The task of the subjects was to listen attentively to the stimuli The activational status of the ambiguous sentence-final words was inferred from the amplitude of the N399 to the targets at two inter-stimulus intervals (ISIs) (100 ms and 1250 ms). At the short ISI, the Broca's aphasics showed clear evidence of activation of the subordinate meaning. In contrast to elderly controls, however, the Broca's aphasics were not successful at selecting the appropriate meaning of the ambiguity in the short ISI version of the experiment. But at the long ISI, in accordance with the performance of the elderly controls, the patients were able to successfully complete the contextual selection process. These results indicate that Broca's aphasics are delayed in the process of contextual selection. It is argued that this finding of delayed selection is compatible with the idea that comprehension deficits in Broca's aphasia result from a delay in the process of integrating lexical information.
  • De Swart, P., & Van Bergen, G. (2014). Unscrambling the lexical nature of weak definites. In A. Aguilar-Guevara, B. Le Bruyn, & J. Zwarts (Eds.), Weak referentiality (pp. 287-310). Amsterdam: Benjamins.

    Abstract

    We investigate how the lexical nature of weak definites influences the phenomenon of direct object scrambling in Dutch. Earlier experiments have indicated that weak definites are more resistant to scrambling than strong definites. We examine how the notion of weak definiteness used in this experimental work can be reduced to lexical connectedness. We explore four different ways of quantifying the relation between a direct object and the verb. Our results show that predictability of a verb given the object (verb cloze probability) provides the best fit to the weak/strong distinction used in the earlier experiments
  • Swift, M. (1998). [Book review of LOUIS-JACQUES DORAIS, La parole inuit: Langue, culture et société dans l'Arctique nord-américain]. Language in Society, 27, 273-276. doi:10.1017/S0047404598282042.

    Abstract

    This volume on Inuit speech follows the evolution of a native language of the North American Arctic, from its historical roots to its present-day linguistic structure and patterns of use from Alaska to Greenland. Drawing on a wide range of research from the fields of linguistics, anthropology, and sociology, Dorais integrates these diverse perspectives in a comprehensive view of native language development, maintenance, and use under conditions of marginalization due to social transition.
  • Swingley, D. (2005). Statistical clustering and the contents of the infant vocabulary. Cognitive Psychology, 50(1), 86-132. doi:10.1016/j.cogpsych.2004.06.001.

    Abstract

    Infants parse speech into word-sized units according to biases that develop in the first year. One bias, present before the age of 7 months, is to cluster syllables that tend to co-occur. The present computational research demonstrates that this statistical clustering bias could lead to the extraction of speech sequences that are actual words, rather than missegmentations. In English and Dutch, these word-forms exhibit the strong–weak (trochaic) pattern that guides lexical segmentation after 8 months, suggesting that the trochaic parsing bias is learned as a generalization from statistically extracted bisyllables, and not via attention to short utterances or to high-frequency bisyllables. Extracted word-forms come from various syntactic classes, and exhibit distributional characteristics enabling rudimentary sorting of words into syntactic categories. The results highlight the importance of infants’ first year in language learning: though they may know the meanings of very few words, infants are well on their way to building a vocabulary.
  • Swingley, D. (2005). 11-month-olds' knowledge of how familiar words sounds. Developmental Science, 8(5), 432-443. doi:10.1111/j.1467-7687.2005.00432.

    Abstract

    During the first year of life, infants' perception of speech becomes tuned to the phonology of the native language, as revealed in laboratory discrimination and categorization tasks using syllable stimuli. However, the implications of these results for the development of the early vocabulary remain controversial, with some results suggesting that infants retain only vague, sketchy phonological representations of words. Five experiments using a preferential listening procedure tested Dutch 11-month-olds' responses to word, nonword and mispronounced-word stimuli. Infants listened longer to words than nonwords, but did not exhibit this response when words were mispronounced at onset or at offset. In addition, infants preferred correct pronunciations to onset mispronunciations. The results suggest that infants' encoding of familiar words includes substantial phonological detail.
  • Swinney, D. A., & Cutler, A. (1979). The access and processing of idiomatic expressions. Journal of Verbal Learning an Verbal Behavior, 18, 523-534. doi:10.1016/S0022-5371(79)90284-6.

    Abstract

    Two experiments examined the nature of access, storage, and comprehension of idiomatic phrases. In both studies a Phrase Classification Task was utilized. In this, reaction times to determine whether or not word strings constituted acceptable English phrases were measured. Classification times were significantly faster to idiom than to matched control phrases. This effect held under conditions involving different categories of idioms, different transitional probabilities among words in the phrases, and different levels of awareness of the presence of idioms in the materials. The data support a Lexical Representation Hypothesis for the processing of idioms.
  • Takashima, A., Wagensveld, B., Van Turennout, M., Zwitserlood, P., Hagoort, P., & Verhoeven, L. (2014). Training-induced neural plasticity in visual-word decoding and the role of syllables. Neuropsychologia, 61, 299-314. doi:10.1016/j.neuropsychologia.2014.06.017.

    Abstract

    To investigate the neural underpinnings of word decoding, and how it changes as a function of repeated exposure, we trained Dutch participants repeatedly over the course of a month of training to articulate a set of novel disyllabic input strings written in Greek script to avoid the use of familiar orthographic representations. The syllables in the input were phonotactically legal combinations but non-existent in the Dutch language, allowing us to assess their role in novel word decoding. Not only trained disyllabic pseudowords were tested but also pseudowords with recombined patterns of syllables to uncover the emergence of syllabic representations. We showed that with extensive training, articulation became faster and more accurate for the trained pseudowords. On the neural level, the initial stage of decoding was reflected by increased activity in visual attention areas of occipito-temporal and occipito-parietal cortices, and in motor coordination areas of the precentral gyrus and the inferior frontal gyrus. After one month of training, memory representations for holistic information (whole word unit) were established in areas encompassing the angular gyrus, the precuneus and the middle temporal gyrus. Syllabic representations also emerged through repeated training of disyllabic pseudowords, such that reading recombined syllables of the trained pseudowords showed similar brain activation to trained pseudowords and were articulated faster than novel combinations of letter strings used in the trained pseudowords.
  • Takashima, A., Bakker, I., Van Hell, J. G., Janzen, G., & McQueen, J. M. (2014). Richness of information about novel words influences how episodic and semantic memory networks interact during lexicalization. NeuroImage, 84, 265-278. doi:10.1016/j.neuroimage.2013.08.023.

    Abstract

    The complementary learning systems account of declarative memory suggests two distinct memory networks, a fast-mapping, episodic system involving the hippocampus, and a slower semantic memory system distributed across the neocortex in which new information is gradually integrated with existing representations. In this study, we investigated the extent to which these two networks are involved in the integration of novel words into the lexicon after extensive learning, and how the involvement of these networks changes after 24 hours. In particular, we explored whether having richer information at encoding influences the lexicalization trajectory. We trained participants with two sets of novel words, one where exposure was only to the words’ phonological forms (the form-only condition), and one where pictures of unfamiliar objects were associated with the words’ phonological forms (the picture-associated condition). A behavioral measure of lexical competition (indexing lexicalization) indicated stronger competition effects for the form-only words. Imaging (fMRI) results revealed greater involvement of phonological lexical processing areas immediately after training in the form-only condition, suggesting tight connections were formed between novel words and existing lexical entries already at encoding. Retrieval of picture-associated novel words involved the episodic/hippocampal memory system more extensively. Although lexicalization was weaker in the picture-associated condition, overall memory strength was greater when tested after a 24 hours’ delay, probably due to the availability of both episodic and lexical memory networks to aid retrieval. It appears that, during lexicalization of a novel word, the relative involvement of different memory networks differs according to the richness of the information about that word available at encoding.
  • Tamaoka, K., Saito, N., Kiyama, S., Timmer, K., & Verdonschot, R. G. (2014). Is pitch accent necessary for comprehension by native Japanese speakers? - An ERP investigation. Journal of Neurolinguistics, 27(1), 31-40. doi:10.1016/j.jneuroling.2013.08.001.

    Abstract

    Not unlike the tonal system in Chinese, Japanese habitually attaches pitch accents to the production of words. However, in contrast to Chinese, few homophonic word-pairs are really distinguished by pitch accents (Shibata & Shibata, 1990). This predicts that pitch accent plays a small role in lexical selection for Japanese language comprehension. The present study investigated whether native Japanese speakers necessarily use pitch accent in the processing of accent-contrasted homophonic pairs (e.g., ame [LH] for 'candy' and ame [HI] for 'rain') measuring electroencephalographic (EEG) potentials. Electrophysiological evidence (i.e., N400) was obtained when a word was semantically incorrect for a given context but not for incorrectly accented homophones. This suggests that pitch accent indeed plays a minor role when understanding Japanese. (C) 2013 Elsevier Ltd. All rights reserved.
  • Tanner, D., Nicol, J., & Brehm, L. (2014). The time-course of feature interference in agreement comprehension: Multiple mechanisms and asymmetrical attraction. Journal of Memory and Language, 76, 195-215. doi:10.1016/j.jml.2014.07.003.

    Abstract

    Attraction interference in language comprehension and production may be as a result of common or different processes. In the present paper, we investigate attraction interference during language comprehension, focusing on the contexts in which interference arises and the time-course of these effects. Using evidence from event-related brain potentials (ERPs) and sentence judgment times, we show that agreement attraction in comprehension is best explained as morphosyntactic interference during memory retrieval. This stands in contrast to attraction as a message-level process involving the representation of the subject NP's number features, which is a strong contributor to attraction in production. We thus argue that the cognitive antecedents of agreement attraction in comprehension are non-identical with those of attraction in production, and moreover, that attraction in comprehension is primarily a consequence of similarity-based interference in cue-based memory retrieval processes. We suggest that mechanisms responsible for attraction during language comprehension are a subset of those involved in language production.
  • Ten Oever, S., Schroeder, C. E., Poeppel, D., Van Atteveldt, N., & Zion-Golumbic, E. (2014). Rhythmicity and cross-modal temporal cues facilitate detection. Neuropsychologia, 63, 43-50. doi:10.1016/j.neuropsychologia.2014.08.008.

    Abstract

    Temporal structure in the environment often has predictive value for anticipating the occurrence of forthcoming events. In this study we investigated the influence of two types of predictive temporal information on the perception of near-threshold auditory stimuli: 1) intrinsic temporal rhythmicity within an auditory stimulus stream and 2) temporally-predictive visual cues. We hypothesized that combining predictive temporal information within- and across-modality should decrease the threshold at which sounds are detected, beyond the advantage provided by each information source alone. Two experiments were conducted in which participants had to detect tones in noise. Tones were presented in either rhythmic or random sequences and were preceded by a temporally predictive visual signal in half of the trials. We show that detection intensities are lower for rhythmic (vs. random) and audiovisual (vs. auditory-only) presentation, independent from response bias, and that this effect is even greater for rhythmic audiovisual presentation. These results suggest that both types of temporal information are used to optimally process sounds that occur at expected points in time (resulting in enhanced detection), and that multiple temporal cues are combined to improve temporal estimates. Our findings underscore the flexibility and proactivity of the perceptual system which uses within- and across-modality temporal cues to anticipate upcoming events and process them optimally. (C) 2014 Elsevier Ltd. All rights reserved.
  • Terwisscha van Scheltinga, A. F., Bakker, S. C., Van Haren, N. E., Boos, H. B., Schnack, H. G., Cahn, W., Hoogman, M., Zwiers, M. P., Fernandez, G., Franke, B., Hulshoff Pol, H. E., & Kahn, R. S. (2014). Association study of fibroblast growth factor genes and brain volumes in schizophrenic patients and healthy controls. Psychiatric Genetics, 24, 283-284. doi:10.1097/YPG.0000000000000057.
  • Theakston, A., Coates, A., & Holler, J. (2014). Handling agents and patients: Representational cospeech gestures help children comprehend complex syntactic constructions. Developmental Psychology, 50(7), 1973-1984. doi:10.1037/a0036694.

    Abstract

    Gesture is an important precursor of children’s early language development, for example, in the transition to multiword speech and as a predictor of later language abilities. However, it is unclear whether gestural input can influence children’s comprehension of complex grammatical constructions. In Study 1, 3- (M = 3 years 5 months) and 4-year-old (M = 4 years 6 months) children witnessed 2-participant actions described using the infrequent object-cleft-construction (OCC; It was the dog that the cat chased). Half saw an experimenter accompanying her descriptions with gestures representing the 2 participants and indicating the direction of action; the remaining children did not witness gesture. Children who witnessed gestures showed better comprehension of the OCC than those who did not witness gestures, both in and beyond the immediate physical context, but this benefit was restricted to the oldest 4-year-olds. In Study 2, a further group of older 4-year-old children (M = 4 years 7 months) witnessed the same 2-participant actions described by an experimenter and accompanied by gestures, but the gesture represented only the 2 participants and not the direction of the action. Again, a benefit of gesture was observed on subsequent comprehension of the OCC. We interpret these findings as demonstrating that representational cospeech gestures can help children comprehend complex linguistic structures by highlighting the roles played by the participants in the event.

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  • Theakston, A. L., Lieven, E. V., Pine, J. M., & Rowland, C. F. (2005). The acquisition of auxiliary syntax: BE and HAVE. Cognitive Linguistics, 16(1), 247-277. doi:10.1515/cogl.2005.16.1.247.

    Abstract

    This study examined patterns of auxiliary provision and omission for the auxiliaries BE and HAVE in a longitudinal data set from 11 children between the ages of two and three years. Four possible explanations for auxiliary omission—a lack of lexical knowledge, performance limitations in production, the Optional Infinitive hypothesis, and patterns of auxiliary use in the input—were examined. The data suggest that although none of these accounts provides a full explanation for the pattern of auxiliary use and nonuse observed in children's early speech, integrating input-based and lexical learning-based accounts of early language acquisition within a constructivist approach appears to provide a possible framework in which to understand the patterns of auxiliary use found in the children's speech. The implications of these findings for models of children's early language acquisition are discussed.
  • Thomassen, A. J., & Kempen, G. (1979). Memory. In J. A. Michon, E. Eijkman, & L. Klerk (Eds.), Handbook of psychonomics (pp. 75-137 ). Amsterdam: North-Holland Publishing Company.
  • Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A. and 269 moreThompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A., Apostolova, L. G., Appel, K., Armstrong, N. J., Aribisala, B., Bastin, M. E., Bauer, M., Bearden, C. E., Bergmann, Ø., Binder, E. B., Blangero, J., Bockholt, H. J., Bøen, E., Bois, C., Boomsma, D. I., Booth, T., Bowman, I. J., Bralten, J., Brouwer, R. M., Brunner, H. G., Brohawn, D. G., Buckner, R. L., Buitelaar, J., Bulayeva, K., Bustillo, J. R., Calhoun, V. D., Cannon, D. M., Cantor, R. M., Carless, M. A., Caseras, X., Cavalleri, G. L., Chakravarty, M. M., Chang, K. D., Ching, C. R. K., Christoforou, A., Cichon, S., Clark, V. P., Conrod, P., Coppola, G., Crespo-Facorro, B., Curran, J. E., Czisch, M., Deary, I. J., de Geus, E. J. C., den Braber, A., Delvecchio, G., Depondt, C., de Haan, L., de Zubicaray, G. I., Dima, D., Dimitrova, R., Djurovic, S., Dong, H., Donohoe, G., Duggirala, R., Dyer, T. D., Ehrlich, S., Ekman, C. J., Elvsåshagen, T., Emsell, L., Erk, S., Espeseth, T., Fagerness, J., Fears, S., Fedko, I., Fernández, G., Fisher, S. E., Foroud, T., Fox, P. T., Francks, C., Frangou, S., Frey, E. M., Frodl, T., Frouin, V., Garavan, H., Giddaluru, S., Glahn, D. C., Godlewska, B., Goldstein, R. Z., Gollub, R. L., Grabe, H. J., Grimm, O., Gruber, O., Guadalupe, T., Gur, R. E., Gur, R. C., Göring, H. H. H., Hagenaars, S., Hajek, T., Hall, G. B., Hall, J., Hardy, J., Hartman, C. A., Hass, J., Hatton, S. N., Haukvik, U. K., Hegenscheid, K., Heinz, A., Hickie, I. B., Ho, B.-C., Hoehn, D., Hoekstra, P. J., Hollinshead, M., Holmes, A. J., Homuth, G., Hoogman, M., Hong, L. E., Hosten, N., Hottenga, J.-J., Pol, H. E. H., Hwang, K. S., Jr, C. R. J., Jenkinson, M., Johnston, C., Jönsson, E. G., Kahn, R. S., Kasperaviciute, D., Kelly, S., Kim, S., Kochunov, P., Koenders, L., Krämer, B., Kwok, J. B. J., Lagopoulos, J., Laje, G., Landen, M., Landman, B. A., Lauriello, J., Lawrie, S. M., Lee, P. H., Le Hellard, S., Lemaître, H., Leonardo, C. D., Li, C.-s., Liberg, B., Liewald, D. C., Liu, X., Lopez, L. M., Loth, E., Lourdusamy, A., Luciano, M., Macciardi, F., Machielsen, M. W. J., MacQueen, G. M., Malt, U. F., Mandl, R., Manoach, D. S., Martinot, J.-L., Matarin, M., Mather, K. A., Mattheisen, M., Mattingsdal, M., Meyer-Lindenberg, A., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Meisenzahl, E., Melle, I., Milaneschi, Y., Mohnke, S., Montgomery, G. W., Morris, D. W., Moses, E. K., Mueller, B. A., Maniega, S. M., Mühleisen, T. W., Müller-Myhsok, B., Mwangi, B., Nauck, M., Nho, K., Nichols, T. E., Nilsson, L.-G., Nugent, A. C., Nyberg, L., Olvera, R. L., Oosterlaan, J., Ophoff, R. A., Pandolfo, M., Papalampropoulou-Tsiridou, M., Papmeyer, M., Paus, T., Pausova, Z., Pearlson, G. D., Penninx, B. W., Peterson, C. P., Pfennig, A., Phillips, M., Pike, G. B., Poline, J.-B., Potkin, S. G., Pütz, B., Ramasamy, A., Rasmussen, J., Rietschel, M., Rijpkema, M., Risacher, S. L., Roffman, J. L., Roiz-Santiañez, R., Romanczuk-Seiferth, N., Rose, E. J., Royle, N. A., Rujescu, D., Ryten, M., Sachdev, P. S., Salami, A., Satterthwaite, T. D., Savitz, J., Saykin, A. J., Scanlon, C., Schmaal, L., Schnack, H. G., Schork, A. J., Schulz, S. C., Schür, R., Seidman, L., Shen, L., Shoemaker, J. M., Simmons, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soares, J. C., Sponheim, S. R., Sprooten, E., Starr, J. M., Steen, V. M., Strakowski, S., Strike, L., Sussmann, J., Sämann, P. G., Teumer, A., Toga, A. W., Tordesillas-Gutierrez, D., Trabzuni, D., Trost, S., Turner, J., Van den Heuvel, M., van der Wee, N. J., van Eijk, K., van Erp, T. G. M., van Haren, N. E. M., van Ent, D. ‘., van Tol, M.-J., Hernández, M. C. V., Veltman, D. J., Versace, A., Völzke, H., Walker, R., Walter, H., Wang, L., Wardlaw, J. M., Weale, M. E., Weiner, M. W., Wen, W., Westlye, L. T., Whalley, H. C., Whelan, C. D., White, T., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Zilles, D., Zwiers, M. P., Thalamuthu, A., Schofield, P. R., Freimer, N. B., Lawrence, N. S., & Drevets, W. (2014). The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior, 8(2), 153-182. doi:10.1007/s11682-013-9269-5.

    Abstract

    The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA’s first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way
  • Thorgrimsson, G., Fawcett, C., & Liszkowski, U. (2014). Infants’ expectations about gestures and actions in third-party interactions. Frontiers in Psychology, 5: 321. doi:10.3389/fpsyg.2014.00321.

    Abstract

    We investigated 14-month-old infants’ expectations toward a third party addressee of communicative gestures and an instrumental action. Infants’ eye movements were tracked as they observed a person (the Gesturer) point, direct a palm-up request gesture, or reach toward an object, and another person (the Addressee) respond by grasping it. Infants’ looking patterns indicate that when the Gesturer pointed or used the palm-up request, infants anticipated that the Addressee would give the object to the Gesturer, suggesting that they ascribed a motive of request to the gestures. In contrast, when the Gesturer reached for the object, and in a control condition where no action took place, the infants did not anticipate the Addressee’s response. The results demonstrate that infants’ recognition of communicative gestures extends to others’ interactions, and that infants can anticipate how third-party addressees will respond to others’ gestures.
  • Tilot, A. K., Gaugler, M. K., Yu, Q., Romigh, T., Yu, W., Miller, R. H., Frazier, T. W., & Eng, C. (2014). Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production. Human Molecular Genetics, 23(12), 3212-3227. doi:10.1093/hmg/ddu031.

    Abstract

    PTEN Hamartoma Tumor Syndrome (PHTS) is an autosomal-dominant genetic condition underlying a subset of autism spectrum disorder (ASD) with macrocephaly. Caused by germline mutations in PTEN, PHTS also causes increased risks of multiple cancers via dysregulation of the PI3K and MAPK signaling pathways. Conditional knockout models have shown that neural Pten regulates social behavior, proliferation and cell size. Although much is known about how the intracellular localization of PTEN regulates signaling in cancer cell lines, we know little of how PTEN localization influences normal brain physiology and behavior. To address this, we generated a germline knock-in mouse model of cytoplasm-predominant Pten and characterized its behavioral and cellular phenotypes. The homozygous Ptenm3m4 mice have decreased total Pten levels including a specific drop in nuclear Pten and exhibit region-specific increases in brain weight. The Ptenm3m4 model displays sex-specific increases in social motivation, poor balance and normal recognition memory—a profile reminiscent of some individuals with high functioning ASD. The cytoplasm-predominant protein caused cellular hypertrophy limited to the soma and led to increased NG2 cell proliferation and accumulation of glia. The animals also exhibit significant astrogliosis and microglial activation, indicating a neuroinflammatory phenotype. At the signaling level, Ptenm3m4 mice show brain region-specific differences in Akt activation. These results demonstrate that differing alterations to the same autism-linked gene can cause distinct behavioral profiles. The Ptenm3m4 model is the first murine model of inappropriately elevated social motivation in the context of normal cognition and may expand the range of autism-related behaviors replicated in animal models.
  • Tooley, K., Konopka, A. E., & Watson, D. (2014). Can intonational phrase structure be primed (like syntactic structure)? Journal of Experimental Psychology: Learning, Memory, and Cognition, 40(2), 348-363. doi:10.1037/a0034900.

    Abstract

    In 3 experiments, we investigated whether intonational phrase structure can be primed. In all experiments, participants listened to sentences in which the presence and location of intonational phrase boundaries were manipulated such that the recording included either no intonational phrase boundaries, a boundary in a structurally dispreferred location, a boundary in a preferred location, or boundaries in both locations. In Experiment 1, participants repeated the sentences to test whether they would reproduce the prosodic structure they had just heard. Experiments 2 and 3 used a prime–target paradigm to evaluate whether the intonational phrase structure heard in the prime sentence might influence that of a novel target sentence. Experiment 1 showed that participants did repeat back sentences that they had just heard with the original intonational phrase structure, yet Experiments 2 and 3 found that exposure to intonational phrase boundaries on prime trials did not influence how a novel target sentence was prosodically phrased. These results suggest that speakers may retain the intonational phrasing of a sentence, but this effect is not long-lived and does not generalize across unrelated sentences. Furthermore, these findings provide no evidence that intonational phrase structure is formulated during a planning stage that is separate from other sources of linguistic information.
  • Tosato, S., Zanoni, M., Bonetto, C., Tozzi, F., Francks, C., Ira, E., Tomassi, S., Bertani, M., Rujescu, D., Giegling, I., St Clair, D., Tansella, M., Ruggeri, M., & Muglia, P. (2014). No association between NRG1 and ErbB4 genes and psychopathological symptoms of Schizophrenia. Neuromolecular Medicine, 16, 742-751. doi:10.1007/s12017-014-8323-9.

    Abstract

    Neuregulin 1 (NRG1) and v-erb-a erythroblastic leukemia viral oncogene homolog 4 (ErbB4) have been extensively studied in schizophrenia susceptibility because of their pivotal role in key neurodevelopmental processes. One of the reasons for the inconsistencies in results could be the fact that the phenotype investigated has mostly the diagnosis of schizophrenia per se, which is widely heterogeneous, both clinically and biologically. In the present study we tested, in a large cohort of 461 schizophrenia patients recruited in Scotland, whether several SNPs in NRG1 and/or ErbB4 are associated with schizophrenia symptom dimensions as evaluated by the Positive and Negative Syndrome Scale (PANSS). We then followed up nominally significant results in a second cohort of 439 schizophrenia subjects recruited in Germany. Using linear regression, we observed two different groups of polymorphisms in NRG1 gene: one showing a nominal association with higher scores of the PANSS positive dimension and the other one with higher scores of the PANSS negative dimension. Regarding ErbB4, a small cluster located in the 5' end of the gene was detected, showing nominal association mainly with negative, general and total dimensions of the PANSS. These findings suggest that some regions of NRG1 and ErbB4 are functionally involved in biological processes that underlie some of the phenotypic manifestations of schizophrenia. Because of the lack of significant association after correction for multiple testing, our analyses should be considered as exploratory and hypothesis generating for future studies.
  • Trilsbeek, P., & Wittenburg, P. (2005). Archiving challenges. In J. Gippert, N. Himmelmann, & U. Mosel (Eds.), Essentials of language documentation (pp. 311-335). Berlin: Mouton de Gruyter.
  • Trilsbeek, P., & Koenig, A. (2014). Increasing the future usage of endangered language archives. In D. Nathan, & P. Austin (Eds.), Language Documentation and Description vol 12 (pp. 151-163). London: SOAS. Retrieved from http://www.elpublishing.org/PID/142.
  • Tsuji, S., Bergmann, C., & Cristia, A. (2014). Community-Augmented Meta-Analyses: Toward Cumulative Data Assessment. Perspectives on Psychological Science, 9(6), 661-665. doi:10.1177/1745691614552498.

    Abstract

    We present the concept of a community-augmented meta-analysis (CAMA), a simple yet novel tool that significantly facilitates the accumulation and evaluation of previous studies within a specific scientific field. A CAMA is a combination of a meta-analysis and an open repository. Like a meta-analysis, it is centered around a psychologically relevant topic and includes methodological details and standardized effect sizes. As in a repository, data do not remain undisclosed and static after publication but can be used and extended by the research community, as anyone can download all information and can add new data via simple forms. Based on our experiences with building three CAMAs, we illustrate the concept and explain how CAMAs can facilitate improving our research practices via the integration of past research, the accumulation of knowledge, and the documentation of file-drawer studies
  • Tsuji, S., & Cristia, A. (2014). Perceptual attunement in vowels: A meta-analysis. Developmental Psychobiology, 56(2), 179-191. doi:10.1002/dev.21179.

    Abstract

    Although the majority of evidence on perceptual narrowing in speech sounds is based on consonants, most models of infant speech perception generalize these findings to vowels, assuming that vowel perception improves for vowel sounds that are present in the infant's native language within the first year of life, and deteriorates for non-native vowel sounds over the same period of time. The present meta-analysis contributes to assessing to what extent these descriptions are accurate in the first comprehensive quantitative meta-analysis of perceptual narrowing in infant vowel discrimination, including results from behavioral, electrophysiological, and neuroimaging methods applied to infants 0–14 months of age. An analysis of effect sizes for native and non-native vowel discrimination over the first year of life revealed that they changed with age in opposite directions, being significant by about 6 months of age
  • Tsuji, S., Nishikawa, K., & Mazuka, R. (2014). Segmental distributions and consonant-vowel association patterns in Japanese infant- and adult-directed speech. Journal of Child Language, 41, 1276-1304. doi:10.1017/S0305000913000469.

    Abstract

    Japanese infant-directed speech (IDS) and adult-directed speech (ADS) were compared on their segmental distributions and consonant-vowel association patterns. Consistent with findings in other languages, a higher ratio of segments that are generally produced early was found in IDS compared to ADS: more labial consonants and low-central vowels, but fewer fricatives. Consonant-vowel associations also favored the early-produced labial-central, coronal-front, coronal-central, and dorsal-back patterns. On the other hand, clear language-specific patterns included a higher frequency of dorsals, affricates, geminates and moraic nasals in IDS. These segments are frequent in adult Japanese, but not in the early productions or the IDS of other studied languages. In combination with previous results, the current study suggests that both fine-tuning (an increased use of early-produced segments) and highlighting (an increased use of language-specifically relevant segments) might modify IDS on segmental level.
  • Tuinman, A., Mitterer, H., & Cutler, A. (2014). Use of syntax in perceptual compensation for phonological reduction. Language and Speech, 57, 68-85. doi:10.1177/0023830913479106.

    Abstract

    Listeners resolve ambiguity in speech by consulting context. Extensive research on this issue has largely relied on continua of sounds constructed to vary incrementally between two phonemic endpoints. In this study we presented listeners instead with phonetic ambiguity of a kind with which they have natural experience: varying degrees of word-final /t/-reduction. In two experiments, Dutch listeners decided whether or not the verb in a sentence such as Maar zij ren(t) soms ‘But she sometimes run(s)’ ended in /t/. In Dutch, presence versus absence of final /t/ distinguishes third- from first-person singular present-tense verbs. Acoustic evidence for /t/ varied from clear to absent, and immediately preceding phonetic context was consistent with more versus less likely deletion of /t/. In both experiments, listeners reported more /t/s in sentences in which /t/ would be syntactically correct. In Experiment 1, the disambiguating syntactic information preceded the target verb, as above, while in Experiment 2, it followed the verb. The syntactic bias was greater for fast than for slow responses in Experiment 1, but no such difference appeared in Experiment 2. We conclude that syntactic information does not directly influence pre-lexical processing, but is called upon in making phoneme decisions.
  • Turco, G., Braun, B., & Dimroth, C. (2014). When contrasting polarity, the Dutch use particles, Germans intonation. Journal of Pragmatics, 62, 94-106. doi:10.1016/j.pragma.2013.09.020.

    Abstract

    This study compares how Dutch and German, two closely related languages, signal a shift from a negative to a positive polarity in two contexts, when contrasting the polarity relative to a different topic situation (In my picture the man washes the car following after In my picture the man does not wash the car, henceforth polarity contrast) and when correcting the polarity of a proposition (The man washes the car following after The man does not wash the car, henceforth polarity correction). Production data show that in both contexts German speakers produced Verum focus (i.e., a high-falling pitch accent on the finite verb), while Dutch speakers mostly used the accented affirmative particle wel. This shows that even lexically and syntactically close languages behave differently when it comes to signalling certain pragmatic functions. Furthermore, we found that in polarity correction contexts, both affirmative particles and Verum focus were realized with stronger prosodic prominence. This difference was found in both languages and might be due to a secondary (syntagmatic) effect of the information structure of the utterance (absence or presence of a contrastive topic).

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