Publications

Displaying 601 - 635 of 635
  • Vernes, S. C., Nicod, J., Elahi, F. M., Coventry, J. A., Kenny, N., Coupe, A.-M., Bird, L. E., Davies, K. E., & Fisher, S. E. (2006). Functional genetic analysis of mutations implicated in a human speech and language disorder. Human Molecular Genetics, 15(21), 3154-3167. doi:10.1093/hmg/ddl392.

    Abstract

    Mutations in the FOXP2 gene cause a severe communication disorder involving speech deficits (developmental verbal dyspraxia), accompanied by wide-ranging impairments in expressive and receptive language. The protein encoded by FOXP2 belongs to a divergent subgroup of forkhead-box transcription factors, with a distinctive DNA-binding domain and motifs that mediate hetero- and homodimerization. Here we report the first direct functional genetic investigation of missense and nonsense mutations in FOXP2 using human cell-lines, including a well-established neuronal model system. We focused on three unusual FOXP2 coding variants, uniquely identified in cases of verbal dyspraxia, assessing expression, subcellular localization, DNA-binding and transactivation properties. Analysis of the R553H forkhead-box substitution, found in all affected members of a large three-generation family, indicated that it severely affects FOXP2 function, chiefly by disrupting nuclear localization and DNA-binding properties. The R328X truncation mutation, segregating with speech/language disorder in a second family, yields an unstable, predominantly cytoplasmic product that lacks transactivation capacity. A third coding variant (Q17L) observed in a single affected child did not have any detectable functional effect in the present study. In addition, we used the same systems to explore the properties of different isoforms of FOXP2, resulting from alternative splicing in human brain. Notably, one such isoform, FOXP2.10+, contains dimerization domains, but no DNA-binding domain, and displayed increased cytoplasmic localization, coupled with aggresome formation. We hypothesize that expression of alternative isoforms of FOXP2 may provide mechanisms for post-translational regulation of transcription factor function.
  • von Stutterheim, C., Flecken, M., & Carroll, M. (2013). Introduction: Conceptualizing in a second language. International Review of Applied Linguistics in Language Teaching, 51(2), 77-85. doi:10.1515/iral-2013-0004.
  • von Stutterheim, C., & Flecken, M. (Eds.). (2013). Principles of information organization in L2 discourse [Special Issue]. International Review of Applied linguistics in Language Teaching (IRAL), 51(2).
  • Vonk, W., Hustinx, L. G., & Simons, W. H. (1992). The use of referential expressions in structuring discourse. Language and Cognitive Processes, 301-333. doi:10.1080/01690969208409389.

    Abstract

    Referential expressions that refer to entities that occur in a text differ in lexical specificity. It is claimed that if these anaphoric expressions are more specific than necessary for their identificational function, they not only relate the current information to the intended referent, but also contribute to the expression of the thematic structure of the discourse and to the comprehension of the thematic structure. In two controlled production experiments, it is demonstrated that thematic shifts are produced when one has to make use of such an overspecified expression, and that overspecified referential expressions are produced when one has to formulate a thematic shift. In two comprehension experiments, using a probe recognition technique, it is shown that an overspecified referential expression decreases the availability of information contained in a sentence that precedes the overspecification. This finding is interpreted in terms of the thematic structuring function of referential expressions in the understanding of discourse.
  • De Vos, C. (2013). Sign-Spatiality in Kata Kolok: How a village sign language of Bali inscribes its signing space [Dissertation abstract]. Sign Language & Linguistics, 16(2), 277-284. doi:10.1075/sll.16.2.08vos.
  • De Vriend, F., Broeder, D., Depoorter, G., van Eerten, L., & Van Uytvanck, D. (2013). Creating & Testing CLARIN Metadata Components. Language Resources and Evaluation, 47(4), 1315-1326. doi:10.1007/s10579-013-9231-6.

    Abstract

    The CLARIN Metadata Infrastructure (CMDI) that is being developed in Common Language Resources and Technology Infrastructure (CLARIN) is a computer-supported framework that combines a flexible component approach with the explicit declaration of semantics. The goal of the Dutch CLARIN project “Creating & Testing CLARIN Metadata Components” was to create metadata components and profiles for a wide variety of existing resources housed at two data centres according to the CMDI specifications. In doing so the principles of the framework were tested. The results of the project are of benefit to other CLARIN-projects that are expected to adhere to the CMDI framework and its accompanying tools.
  • Wagensveld, B., Segers, E., Van Alphen, P. M., & Verhoeven, L. (2013). The role of lexical representations and phonological overlap in rhyme judgments of beginning, intermediate and advanced readers. Learning and Individual Differences, 23, 64-71. doi:10.1016/j.lindif.2012.09.007.

    Abstract

    Studies have shown that prereaders find globally similar non-rhyming pairs (i.e., bell–ball) difficult to judge. Although this effect has been explained as a result of ill-defined lexical representations, others have suggested that it is part of an innate tendency to respond to phonological overlap. In the present study we examined this effect over time. Beginning, intermediate and advanced readers were presented with a rhyme judgment task containing rhyming, phonologically similar, and unrelated non-rhyming pairs. To examine the role of lexical representations, participants were presented with both words and pseudowords. Outcomes showed that pseudoword processing was difficult for children but not for adults. The global similarity effect was present in both children and adults. The findings imply that holistic representations cannot explain the incapacity to ignore similarity relations during rhyming. Instead, the data provide more evidence for the idea that global similarity processing is part of a more fundamental innate phonological processing capacity.
  • Wagensveld, B., Van Alphen, P. M., Segers, E., Hagoort, P., & Verhoeven, L. (2013). The neural correlates of rhyme awareness in preliterate and literate children. Clinical Neurophysiology, 124, 1336-1345. doi:10.1016/j.clinph.2013.01.022.

    Abstract

    Objective Most rhyme awareness assessments do not encompass measures of the global similarity effect (i.e., children who are able to perform simple rhyme judgments get confused when presented with globally similar non-rhyming pairs). The present study examines the neural nature of this effect by studying the N450 rhyme effect. Methods Behavioral and electrophysiological responses of Dutch pre-literate kindergartners and literate second graders were recorded while they made rhyme judgments of word pairs in three conditions; phonologically rhyming (e.g., wijn-pijn), overlapping non-rhyming (e.g., pen-pijn) and unrelated non-rhyming pairs (e.g., boom-pijn). Results Behaviorally, both groups had difficulty judging overlapping but not rhyming and unrelated pairs. The neural data of second graders showed overlapping pairs were processed in a similar fashion as unrelated pairs; both showed a more negative deflection of the N450 component than rhyming items. Kindergartners did not show a typical N450 rhyme effect. However, some other interesting ERP differences were observed, indicating preliterates are sensitive to rhyme at a certain level. Significance Rhyme judgments of globally similar items rely on the same process as rhyme judgments of rhyming and unrelated items. Therefore, incorporating a globally similar condition in rhyme assessments may lead to a more in-depth measure of early phonological awareness skills. Highlights Behavioral and electrophysiological responses were recorded while (pre)literate children made rhyme judgments of rhyming, overlapping and unrelated words. Behaviorally both groups had difficulty judging overlapping pairs as non-rhyming while overlapping and unrelated neural patterns were similar in literates. Preliterates show a different pattern indicating a developing phonological system.
  • Wagner, A. (2013). Cross-language similarities and differences in the uptake of place information. Journal of the Acoustical Society of America, 133, 4256-4267. doi:10.1121/1.4802904.

    Abstract

    Cross-language differences in the use of coarticulatory cues for the identification of fricatives have been demonstrated in a phoneme detection task: Listeners with perceptually similar fricative pairs in their native phoneme inventories (English, Polish, Spanish) relied more on cues from vowels than listeners with perceptually more distinct fricative contrasts (Dutch and German). The present gating study further investigated these cross-language differences and addressed three questions. (1) Are there cross-language differences in informativeness of parts of the speech signal regarding place of articulation for fricative identification? (2) Are such cross-language differences fricative-specific, or do they extend to the perception of place of articulation for plosives? (3) Is such language-specific uptake of information based on cues preceding or following the consonantal constriction? Dutch, Italian, Polish, and Spanish listeners identified fricatives and plosives in gated CV and VC syllables. The results showed cross-language differences in the informativeness of coarticulatory cues for fricative identification: Spanish and Polish listeners extracted place of articulation information from shorter portions of VC syllables. No language-specific differences were found for plosives, suggesting that greater reliance on coarticulatory cues did not generalize to other phoneme types. The language-specific differences for fricatives were based on coarticulatory cues into the consonant.
  • Wagner, A., Ernestus, M., & Cutler, A. (2006). Formant transitions in fricative identification: The role of native fricative inventory. Journal of the Acoustical Society of America, 120(4), 2267-2277. doi:10.1121/1.2335422.

    Abstract

    The distribution of energy across the noise spectrum provides the primary cues for the identification of a fricative. Formant transitions have been reported to play a role in identification of some fricatives, but the combined results so far are conflicting. We report five experiments testing the hypothesis that listeners differ in their use of formant transitions as a function of the presence of spectrally similar fricatives in their native language. Dutch, English, German, Polish, and Spanish native listeners performed phoneme monitoring experiments with pseudowords containing either coherent or misleading formant transitions for the fricatives / s / and / f /. Listeners of German and Dutch, both languages without spectrally similar fricatives, were not affected by the misleading formant transitions. Listeners of the remaining languages were misled by incorrect formant transitions. In an untimed labeling experiment both Dutch and Spanish listeners provided goodness ratings that revealed sensitivity to the acoustic manipulation. We conclude that all listeners may be sensitive to mismatching information at a low auditory level, but that they do not necessarily take full advantage of all available systematic acoustic variation when identifying phonemes. Formant transitions may be most useful for listeners of languages with spectrally similar fricatives.
  • Walters, J., Rujescu, D., Franke, B., Giegling, I., Vasquez, A., Hargreaves, A., Russo, G., Morris, D., Hoogman, M., Da Costa, A., Moskvina, V., Fernandez, G., Gill, M., Corvin, A., O'Donovan, M., Donohoe, G., & Owen, M. (2013). The role of the major histocompatibility complex region in cognition and brain structure: A schizophrenia GWAS follow-up. American Journal of Psychiatry, 170, 877-885. doi:10.1176/appi.ajp.2013.12020226.

    Abstract

    Objective The authors investigated the effects of recently identified genome-wide significant schizophrenia genetic risk variants on cognition and brain structure. Method A panel of six single-nucleotide polymorphisms (SNPs) was selected to represent genome-wide significant loci from three recent genome-wide association studies (GWAS) for schizophrenia and was tested for association with cognitive measures in 346 patients with schizophrenia and 2,342 healthy comparison subjects. Nominally significant results were evaluated for replication in an independent case-control sample. For SNPs showing evidence of association with cognition, associations with brain structural volumes were investigated in a large independent healthy comparison sample. Results Five of the six SNPs showed no significant association with any cognitive measure. One marker in the major histocompatibility complex (MHC) region, rs6904071, showed independent, replicated evidence of association with delayed episodic memory and was significant when both samples were combined. In the combined sample of up to 3,100 individuals, this SNP was associated with widespread effects across cognitive domains, although these additional associations were no longer significant after adjusting for delayed episodic memory. In the large independent structural imaging sample, the same SNP was also associated with decreased hippocampal volume. Conclusions The authors identified a SNP in the MHC region that was associated with cognitive performance in patients with schizophrenia and healthy comparison subjects. This SNP, rs6904071, showed a replicated association with episodic memory and hippocampal volume. These findings implicate the MHC region in hippocampal structure and functioning, consistent with the role of MHC proteins in synaptic development and function. Follow-up of these results has the potential to provide insights into the pathophysiology of schizophrenia and cognition.

    Additional information

    Hoogman_2013_JourAmePsy.supp.pdf
  • Wang, L., Bastiaansen, M. C. M., Yang, Y., & Hagoort, P. (2013). ERP evidence on the interaction between information structure and emotional salience of words. Cognitive, Affective and Behavioral Neuroscience, 13, 297-310. doi:10.3758/s13415-012-0146-2.

    Abstract

    Both emotional words and words focused by information structure can capture attention. This study examined the interplay between emotional salience and information structure in modulating attentional resources in the service of integrating emotional words into sentence context. Event-related potentials (ERPs) to affectively negative, neutral, and positive words, which were either focused or nonfocused in question–answer pairs, were evaluated during sentence comprehension. The results revealed an early negative effect (90–200 ms), a P2 effect, as well as an effect in the N400 time window, for both emotional salience and information structure. Moreover, an interaction between emotional salience and information structure occurred within the N400 time window over right posterior electrodes, showing that information structure influences the semantic integration only for neutral words, but not for emotional words. This might reflect the fact that the linguistic salience of emotional words can override the effect of information structure on the integration of words into context. The interaction provides evidence for attention–emotion interactions at a later stage of processing. In addition, the absence of interaction in the early time window suggests that the processing of emotional information is highly automatic and independent of context. The results suggest independent attention capture systems of emotional salience and information structure at the early stage but an interaction between them at a later stage, during the semantic integration of words.
  • Wang, L., Zhu, Z., Bastiaansen, M. C. M., Hagoort, P., & Yang, Y. (2013). Recognizing the emotional valence of names: An ERP study. Brain and Language, 125, 118-127. doi:10.1016/j.bandl.2013.01.006.

    Abstract

    Unlike common nouns, person names refer to unique entities and generally have a referring function. We used event-related potentials to investigate the time course of identifying the emotional meaning of nouns and names. The emotional valence of names and nouns were manipulated separately. The results show early N1 effects in response to emotional valence only for nouns. This might reflect automatic attention directed towards emotional stimuli. The absence of such an effect for names supports the notion that the emotional meaning carried by names is accessed after word recognition and person identification. In addition, both names with negative valence and emotional nouns elicited late positive effects, which have been associated with evaluation of emotional significance. This positive effect started earlier for nouns than for names, but with similar durations. Our results suggest that distinct neural systems are involved in the retrieval of names’ and nouns’ emotional meaning.
  • Wang, L., & Chu, M. (2013). The role of beat gesture and pitch accent in semantic processing: An ERP study. Neuropsychologia, 51(13), 2847-2855. doi:10.1016/j.neuropsychologia.2013.09.027.

    Abstract

    The present study investigated whether and how beat gesture (small baton-like hand movements used to emphasize information in speech) influences semantic processing as well as its interaction with pitch accent during speech comprehension. Event-related potentials were recorded as participants watched videos of a person gesturing and speaking simultaneously. The critical words in the spoken sentences were accompanied by a beat gesture, a control hand movement, or no hand movement, and were expressed either with or without pitch accent. We found that both beat gesture and control hand movement induced smaller negativities in the N400 time window than when no hand movement was presented. The reduced N400s indicate that both beat gesture and control movement facilitated the semantic integration of the critical word into the sentence context. In addition, the words accompanied by beat gesture elicited smaller negativities in the N400 time window than those accompanied by control hand movement over right posterior electrodes, suggesting that beat gesture has a unique role for enhancing semantic processing during speech comprehension. Finally, no interaction was observed between beat gesture and pitch accent, indicating that they affect semantic processing independently.
  • Warmelink, L., Vrij, A., Mann, S., Leal, S., & Poletiek, F. H. (2013). The effects of unexpected questions on detecting familiar and unfamiliar lies. Psychiatry, Psychology and law, 20(1), 29-35. doi:10.1080/13218719.2011.619058.

    Abstract

    Previous research suggests that lie detection can be improved by asking the interviewee unexpected questions. The present experiment investigates the effect of two types of unexpected questions: background questions and detail questions, on detecting lies about topics with which the interviewee is (a) familiar or (b) unfamiliar. In this experiment, 66 participants read interviews in which interviewees answered background or detail questions, either truthfully or deceptively. Those who answered deceptively could be lying about a topic they were familiar with or about a topic they were unfamiliar with. The participants were asked to judge whether the interviewees were lying. The results revealed that background questions distinguished truths from both types of lies, while the detail questions distinguished truths from unfamiliar lies, but not from familiar lies. The implications of these findings are discussed.
  • Warner, N., Good, E., Jongman, A., & Sereno, J. (2006). Orthographic vs. morphological incomplete neutralization effects. Journal of Phonetics, 34(2), 285-293. doi:10.1016/j.wocn.2004.11.003.

    Abstract

    This study, following up on work on Dutch by Warner, Jongman, Sereno, and Kemps (2004. Journal of Phonetics, 32, 251–276), investigates the influence of orthographic distinctions and underlying morphological distinctions on the small sub-phonemic durational differences that have been called incomplete neutralization. One part of the previous work indicated that an orthographic geminate/singleton distinction could cause speakers to produce an incomplete neutralization effect. However, one interpretation of the materials in that experiment is that they contain an underlying difference in the phoneme string at the level of concatenation of morphemes, rather than just an orthographic difference. Thus, the previous effect might simply be another example of incomplete neutralization of a phonemic distinction. The current experiment, also on Dutch, uses word pairs which have the same underlying morphological contrast, but do not differ in orthography. These new materials show no incomplete neutralization, and thus support the hypothesis that orthography, but not underlying morphological differences, can cause incomplete neutralization effects.
  • Warren, J. E., Sauter, D., Eisner, F., Wiland, J., Dresner, M. A., Wise, R. J. S., Rosen, S., & Scott, S. K. (2006). Positive emotions preferentially engage an auditory–motor “mirror” system. The Journal of Neuroscience, 26(50), 13067-13075. doi:10.1523/JNEUROSCI.3907-06.2006.

    Abstract

    Social interaction relies on the ability to react to communication signals. Although cortical sensory–motor “mirror” networks are thought to play a key role in visual aspects of primate communication, evidence for a similar generic role for auditory–motor interaction in primate nonverbal communication is lacking. We demonstrate that a network of human premotor cortical regions activated during facial movement is also involved in auditory processing of affective nonverbal vocalizations. Within this auditory–motor mirror network, distinct functional subsystems respond preferentially to emotional valence and arousal properties of heard vocalizations. Positive emotional valence enhanced activation in a left posterior inferior frontal region involved in representation of prototypic actions, whereas increasing arousal enhanced activation in presupplementary motor area cortex involved in higher-order motor control. Our findings demonstrate that listening to nonverbal vocalizations can automatically engage preparation of responsive orofacial gestures, an effect that is greatest for positive-valence and high-arousal emotions. The automatic engagement of responsive orofacial gestures by emotional vocalizations suggests that auditory–motor interactions provide a fundamental mechanism for mirroring the emotional states of others during primate social behavior. Motor facilitation by positive vocal emotions suggests a basic neural mechanism for establishing cohesive bonds within primate social groups.
  • Wassenaar, M., Hagoort, P., & Brown, C. M. (1997). Syntactic ERP effects in Broca's aphasics with agrammatic comprehension. Brain and Language, 60, 61-64. doi:10.1006/brln.1997.1911.
  • Weber, A., Braun, B., & Crocker, M. W. (2006). Finding referents in time: Eye-tracking evidence for the role of contrastive accents. Language and Speech, 49(3), 367-392.

    Abstract

    In two eye-tracking experiments the role of contrastive pitch accents during the on-line determination of referents was examined. In both experiments, German listeners looked earlier at the picture of a referent belonging to a contrast pair (red scissors, given purple scissors) when instructions to click on it carried a contrastive accent on the color adjective (L + H*) than when the adjective was not accented. In addition to this prosodic facilitation, a general preference to interpret adjectives contrastively was found in Experiment 1: Along with the contrast pair, a noncontrastive referent was displayed (red vase) and listeners looked more often at the contrastive referent than at the noncontrastive referent even when the adjective was not focused. Experiment 2 differed from Experiment 1 in that the first member of the contrast pair (purple scissors) was introduced with a contrastive accent, thereby strengthening the salience of the contrast. In Experiment 2, listeners no longer preferred a contrastive interpretation of adjectives when the accent in a subsequent instruction was not contrastive. In sum, the results support both an early role for prosody in reference determination and an interpretation of contrastive focus that is dependent on preceding prosodic context.
  • Weber, A., & Cutler, A. (2006). First-language phonotactics in second-language listening. Journal of the Acoustical Society of America, 119(1), 597-607. doi:10.1121/1.2141003.

    Abstract

    Highly proficient German users of English as a second language, and native speakers of American English, listened to nonsense sequences and responded whenever they detected an embedded English word. The responses of both groups were equivalently facilitated by preceding context that both by English and by German phonotactic constraints forced a boundary at word onset (e.g., lecture was easier to detect in moinlecture than in gorklecture, and wish in yarlwish than in plookwish. The American L1 speakers’ responses were strongly facilitated, and the German listeners’ responses almost as strongly facilitated, by contexts that forced a boundary in English but not in German thrarshlecture, glarshwish. The German listeners’ responses were significantly facilitated also by contexts that forced a boundary in German but not in English )moycelecture, loitwish, while L1 listeners were sensitive to acoustic boundary cues in these materials but not to the phonotactic sequences. The pattern of results suggests that proficient L2 listeners can acquire the phonotactic probabilities of an L2 and use them to good effect in segmenting continuous speech, but at the same time they may not be able to prevent interference from L1 constraints in their L2 listening.
  • Weber, A., Grice, M., & Crocker, M. W. (2006). The role of prosody in the interpretation of structural ambiguities: A study of anticipatory eye movements. Cognition, 99, B63-B72. doi:10.1016/j.cognition.2005.07.001.

    Abstract

    An eye-tracking experiment examined whether prosodic cues can affect the interpretation of grammatical functions in the absence of clear morphological information. German listeners were presented with scenes depicting three potential referents while hearing temporarily ambiguous SVO and OVS sentences. While case marking on the first noun phrase (NP) was ambiguous, clear case marking on the second NP disambiguated sentences towards SVO or OVS. Listeners interpreted caseambiguous NP1s more often as Subject, and thus expected an Object as upcoming argument, only when sentence beginnings carried an SVO-type intonation. This was revealed by more anticipatory eye movements to suitable Patients (Objects) than Agents (Subjects) in the visual scenes. No such preference was found when sentence beginnings had a clearly OVS-type intonation. Prosodic cues were integrated rapidly enough to affect listeners’ interpretation of grammatical function before disambiguating case information was available. We conclude that in addition to manipulating attachment ambiguities, prosody can influence the interpretation of constituent order ambiguities.
  • Wegener, C. (2006). Savosavo body part terminology. Language Sciences, 28(2-3), 344-359. doi:10.1016/j.langsci.2005.11.005.

    Abstract

    This paper provides a description of body part terminology used in Savosavo, a Papuan language of the Solomon Islands. The first part of the paper lists the known terms and discusses their meanings. This is followed by an analysis of their structural properties. Finally, the paper discusses partonomic relations in Savosavo and argues that it is difficult to structure the body part terminology hierarchically, because there is no linguistic evidence for part–whole relations between body parts.
  • Weisfelt, M., Hoogman, M., van de Beek, D., de Gans, J., Dreschler, W. A., & Schmand, B. A. (2006). Dexamethasone and long-term outcome in adults with bacterial meningitis. Annals of Neurology, 60, 456-468. doi:10.1002/ana.20944.

    Abstract

    This follow-up study of the European Dexamethasone Study was designed to examine the potential harmful effect of adjunctive dexamethasone treatment on long-term neuropsychological outcome in adults with bacterial meningitis. METHODS: Neurological, audiological, and neuropsychological examinations were performed in adults who survived pneumococcal or meningococcal meningitis. RESULTS: Eighty-seven of 99 (88%) eligible patients were included in the follow-up study; 46 (53%) were treated with dexamethasone and 41 (47%) with placebo. Median time between meningitis and testing was 99 months. Neuropsychological evaluation showed no significant differences between patients treated with dexamethasone and placebo. The proportions of patients with persisting neurological sequelae or hearing loss were similar in the dexamethasone and placebo groups. The overall rate of cognitive dysfunction did not differ significantly between patients and control subjects; however, patients after pneumococcal meningitis had a higher rate of cognitive dysfunction (21 vs 6%; p = 0.05) and experienced more impairment of everyday functioning due to physical problems (p = 0.05) than those after meningococcal meningitis. INTERPRETATION: Treatment with adjunctive dexamethasone is not associated with an increased risk for long-term cognitive impairment. Adults who survive pneumococcal meningitis are at significant risk for long-term neuropsychological abnormalities.
  • Weisfelt, M., van de Beek, D., Hoogman, M., Hardeman, C., de Gans, J., & Schmand, B. (2006). Cognitive outcome in adults with moderate disability after pneumococcal meningitis. Journal of Infection, 52, 433-439. doi:10.1016/j.jinf.2005.08.014.

    Abstract

    Objectives To assess cognitive outcome and quality of life in patients with moderate disability after bacterial meningitis as compared to patients with good recovery. Methods Neuropsychological evaluation was performed in 40 adults after pneumococcal meningitis; 20 patients with moderate disability at discharge on the glasgow outcome scale (GOS score 4) and 20 with good recovery (GOS score 5). Results Patients with GOS score 4 had similar test results as compared to patients with GOS score 5 for the neuropsychological domains ‘intelligence’, ‘memory’ and ‘attention and executive functioning’. Patients with GOS score 4 showed less cognitive slowness than patients with GOS score 5. In a linear regression analysis cognitive speed was related to current intelligence, years of education and time since meningitis. Overall performance on the speed composite score correlated significantly with time since meningitis (−0.62; P<0.001). Therefore, difference between both groups may have been related to a longer time between meningitis and testing for GOS four patients (29 vs. 12 months; P<0.001). Conclusions Patients with moderate disability after bacterial meningitis are not at higher risk for neuropsychological abnormalities than patients with good recovery. In addition, cognitive slowness after bacterial meningitis may be reversible in time.
  • Wheeldon, L. R., & Levelt, W. J. M. (1995). Monitoring the time course of phonological encoding. Journal of Memory and Language, 34(3), 311-334. doi:10.1006/jmla.1995.1014.

    Abstract

    Three experiments examined the time course of phonological encoding in speech production. A new methodology is introduced in which subjects are required to monitor their internal speech production for prespecified target segments and syllables. Experiment 1 demonstrated that word initial target segments are monitored significantly faster than second syllable initial target segments. The addition of a concurrent articulation task (Experiment 1b) had a limited effect on performance, excluding the possibility that subjects are monitoring a subvocal articulation of the carrier word. Moreover, no relationship was observed between the pattern of monitoring latencies and the timing of the targets in subjects′ overt speech. Subjects are not, therefore, monitoring an internal phonetic representation of the carrier word. Experiment 2 used the production monitoring task to replicate the syllable monitoring effect observed in speech perception experiments: responses to targets were faster when they corresponded to the initial syllable of the carrier word than when they did not. We conclude that subjects are monitoring their internal generation of a syllabified phonological representation. Experiment 3 provides more detailed evidence concerning the time course of the generation of this representation by comparing monitoring latencies to targets within, as well as between, syllables. Some amendments to current models of phonological encoding are suggested in light of these results.
  • White, S. A., Fisher, S. E., Geschwind, D. H., Scharff, C., & Holy, T. E. (2006). Singing mice, songbirds, and more: Models for FOXP2 function and dysfunction in human speech and language. The Journal of Neuroscience, 26(41), 10376-10379. doi:10.1523/JNEUROSCI.3379-06.2006.

    Abstract

    In 2001, a point mutation in the forkhead box P2 (FOXP2) coding sequence was identified as the basis of an inherited speech and language disorder suffered by members of the family known as "KE." This mini-symposium review focuses on recent findings and research-in-progress, primarily from five laboratories. Each aims at capitalizing on the FOXP2 discovery to build a neurobiological bridge between molecule and phenotype. Below, we describe genetic through behavioral techniques used currently to investigate FoxP2 in birds, rodents, and humans for discovery of the neural bases of vocal learning and language.
  • Whitmarsh, S., Udden, J., Barendregt, H., & Petersson, K. M. (2013). Mindfulness reduces habitual responding based on implicit knowledge: Evidence from artificial grammar learning. Consciousness and Cognition, (3), 833-845. doi:10.1016/j.concog.2013.05.007.

    Abstract

    Participants were unknowingly exposed to complex regularities in a working memory task. The existence of implicit knowledge was subsequently inferred from a preference for stimuli with similar grammatical regularities. Several affective traits have been shown to influence
    AGL performance positively, many of which are related to a tendency for automatic responding. We therefore tested whether the mindfulness trait predicted a reduction of grammatically congruent preferences, and used emotional primes to explore the influence of affect. Mindfulness was shown to correlate negatively with grammatically congruent responses. Negative primes were shown to result in faster and more negative evaluations.
    We conclude that grammatically congruent preference ratings rely on habitual responses, and that our findings provide empirical evidence for the non-reactive disposition of the mindfulness trait.
  • Wilkins, D. P., & Hill, D. (1995). When "go" means "come": Questioning the basicness of basic motion verbs. Cognitive Linguistics, 6, 209-260. doi:10.1515/cogl.1995.6.2-3.209.

    Abstract

    The purpose of this paper is to question some of the basic assumpiions concerning motion verbs. In particular, it examines the assumption that "come" and "go" are lexical universals which manifest a universal deictic Opposition. Against the background offive working hypotheses about the nature of'come" and ''go", this study presents a comparative investigation of t wo unrelated languages—Mparntwe Arrernte (Pama-Nyungan, Australian) and Longgu (Oceanic, Austronesian). Although the pragmatic and deictic "suppositional" complexity of"come" and "go" expressions has long been recognized, we argue that in any given language the analysis of these expressions is much more semantically and systemically complex than has been assumed in the literature. Languages vary at the lexical semantic level äs t o what is entailed by these expressions, äs well äs differing äs t o what constitutes the prototype and categorial structure for such expressions. The data also strongly suggest that, ifthere is a lexical universal "go", then this cannof be an inherently deictic expression. However, due to systemic Opposition with "come", non-deictic "go" expressions often take on a deictic Interpretation through pragmatic attribution. Thus, this crosslinguistic investigation of "come" and "go" highlights the need to consider semantics and pragmatics äs modularly separate.
  • Willems, R. M. (2013). Can literary studies contribute to cognitive neuroscience? Journal of literary semantics, 42(2), 217-222. doi:10.1515/jls-2013-0011.
  • Witteman, M. J., Weber, A., & McQueen, J. M. (2013). Foreign accent strength and listener familiarity with an accent co-determine speed of perceptual adaptation. Attention, Perception & Psychophysics, 75, 537-556. doi:10.3758/s13414-012-0404-y.

    Abstract

    We investigated how the strength of a foreign accent and varying types of experience with foreign-accented speech influence the recognition of accented words. In Experiment 1, native Dutch listeners with limited or extensive prior experience with German-accented Dutch completed a cross-modal priming experiment with strongly, medium, and weakly accented words. Participants with limited experience were primed by the medium and weakly accented words, but not by the strongly accented words. Participants with extensive experience were primed by all accent types. In Experiments 2 and 3, Dutch listeners with limited experience listened to a short story before doing the cross-modal priming task. In Experiment 2, the story was spoken by the priming task speaker and either contained strongly accented words or did not. Strongly accented exposure led to immediate priming by novel strongly accented words, while exposure to the speaker without strongly accented tokens led to priming only in the experiment’s second half. In Experiment 3, listeners listened to the story with strongly accented words spoken by a different German-accented speaker. Listeners were primed by the strongly accented words, but again only in the experiment’s second half. Together, these results show that adaptation to foreign-accented speech is rapid but depends on accent strength and on listener familiarity with those strongly accented words.
  • Wright, S. E., & Windhouwer, M. (2013). ISOcat - im Reich der Datenkategorien. eDITion: Fachzeitschrift für Terminologie, 9(1), 8-12.

    Abstract

    Im ISOcat-Datenkategorie-Register (Data Category Registry, www.isocat.org) des Technischen Komitees ISO/TC 37 (Terminology and other language and content resources) werden Feldnamen und Werte für Sprachressourcen beschrieben. Empfohlene Feldnamen und zuverlässige Definitionen sollen dazu beitragen, dass Sprachdaten unabhängig von Anwendungen, Plattformen und Communities of Practice (CoP) wiederverwendet werden können. Datenkategorie-Gruppen (Data Category Selections) können eingesehen, ausgedruckt, exportiert und nach kostenloser Registrierung auch neu erstellt werden.
  • Wurm, L. H., Ernestus, M., Schreuder, R., & Baayen, R. H. (2006). Dynamics of the auditory comprehension of prefixed words: Cohort entropies and conditional root uniqueness points. The Mental Lexicon, 1(1), 125-146.

    Abstract

    This auditory lexical decision study shows that cohort entropies, conditional root uniqueness points, and morphological family size all contribute to the dynamics of the auditory comprehension of prefixed words. Three entropy measures calculated for different positions in the stem of Dutch prefixed words revealed facilitation for higher entropies, except at the point of disambiguation, where we observed inhibition. Morphological family size was also facilitatory, but only for prefixed words in which the conditional root uniqueness point coincided with the conventional uniqueness point. For words with early conditional disambiguation, in contrast, only the morphologically related words that were onset-aligned with the target word facilitated lexical decision.
  • Zavala, R. (1997). Functional analysis of Akatek voice constructions. International Journal of American Linguistics, 63(4), 439-474.

    Abstract

    L'A. étudie les corrélations entre structure syntaxique et fonction pragmatique dans les alternances de voix en akatek, une langue maya appartenant au sous-groupe Q'anjob'ala. Les alternances pragmatiques de voix sont les mécanismes par lesquels les langues encodent les différents degrés de topicalité des deux principaux participants d'un événement sémantiquement transitif, l'agent et le patient. A l'aide d'une analyse quantitative, l'A. évalue la topicalité de ces participants et identifie les structures syntaxiques permettant d'exprimer les quatre principales fonctions de voix en akatek : active-directe, inverse, passive et antipassive
  • Zeshan, U., Escobedo Delgado, C. E., Dikyuva, H., Panda, S., & De Vos, C. (2013). Cardinal numerals in rural sign languages: Approaching cross-modal typology. Linguistic Typology, 17(3), 357-396. doi:10.1515/lity-2013-0019.

    Abstract

    This article presents data on cardinal numerals in three sign languages from small-scale communities with hereditary deafness. The unusual features found in these data considerably extend the known range of typological variety across sign languages. Some features, such as non-decimal numeral bases, are unattested in sign languages, but familiar from spoken languages, while others, such as subtractive sub-systems, are rare in sign and speech. We conclude that for a complete typological appraisal of a domain, an approach to cross-modal typology, which includes a typologically diverse range of sign languages in addition to spoken languages, is both instructive and feasible.
  • De Zubicaray, G. I., Acheson, D. J., & Hartsuiker, R. J. (Eds.). (2013). Mind what you say - general and specific mechanisms for monitoring in speech production [Research topic] [Special Issue]. Frontiers in Human Neuroscience. Retrieved from http://www.frontiersin.org/human_neuroscience/researchtopics/mind_what_you_say_-_general_an/1197.

    Abstract

    Psycholinguistic research has typically portrayed speech production as a relatively automatic process. This is because when errors are made, they occur as seldom as one in every thousand words we utter. However, it has long been recognised that we need some form of control over what we are currently saying and what we plan to say. This capacity to both monitor our inner speech and self-correct our speech output has often been assumed to be a property of the language comprehension system. More recently, it has been demonstrated that speech production benefits from interfacing with more general cognitive processes such as selective attention, short-term memory (STM) and online response monitoring to resolve potential conflict and successfully produce the output of a verbal plan. The conditions and levels of representation according to which these more general planning, monitoring and control processes are engaged during speech production remain poorly understood. Moreover, there remains a paucity of information about their neural substrates, despite some of the first evidence of more general monitoring having come from electrophysiological studies of error related negativities (ERNs). While aphasic speech errors continue to be a rich source of information, there has been comparatively little research focus on instances of speech repair. The purpose of this Frontiers Research Topic is to provide a forum for researchers to contribute investigations employing behavioural, neuropsychological, electrophysiological, neuroimaging and virtual lesioning techniques. In addition, while the focus of the research topic is on novel findings, we welcome submission of computational simulations, review articles and methods papers.

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