Publications

Displaying 901 - 987 of 987
  • Van Heuven, W. J. B., Schriefers, H., Dijkstra, T., & Hagoort, P. (2008). Language conflict in the bilingual brain. Cerebral Cortex, 18(11), 2706-2716. doi:10.1093/cercor/bhn030.

    Abstract

    The large majority of humankind is more or less fluent in 2 or even more languages. This raises the fundamental question how the language network in the brain is organized such that the correct target language is selected at a particular occasion. Here we present behavioral and functional magnetic resonance imaging data showing that bilingual processing leads to language conflict in the bilingual brain even when the bilinguals’ task only required target language knowledge. This finding demonstrates that the bilingual brain cannot avoid language conflict, because words from the target and nontarget languages become automatically activated during reading. Importantly, stimulus-based language conflict was found in brain regions in the LIPC associated with phonological and semantic processing, whereas response-based language conflict was only found in the pre-supplementary motor area/anterior cingulate cortex when language conflict leads to response conflicts.
  • Van der Valk, R. J. P., Duijts, L., Timpson, N. J., Salam, M. T., Standl, M., Curtin, J. A., Genuneit, J., Kerhof, M., Kreiner-Møller, E., Cáceres, A., Gref, A., Liang, L. L., Taal, H. R., Bouzigon, E., Demenais, F., Nadif, R., Ober, C., Thompson, E. E., Estrada, K., Hofman, A. and 39 moreVan der Valk, R. J. P., Duijts, L., Timpson, N. J., Salam, M. T., Standl, M., Curtin, J. A., Genuneit, J., Kerhof, M., Kreiner-Møller, E., Cáceres, A., Gref, A., Liang, L. L., Taal, H. R., Bouzigon, E., Demenais, F., Nadif, R., Ober, C., Thompson, E. E., Estrada, K., Hofman, A., Uitterlinden, A. G., van Duijn, C., Rivadeneira, F., Li, X., Eckel, S. P., Berhane, K., Gauderman, W. J., Granell, R., Evans, D. M., St Pourcain, B., McArdle, W., Kemp, J. P., Smith, G. D., Tiesler, C. M. T., Flexeder, C., Simpson, A., Murray, C. S., Fuchs, O., Postma, D. S., Bønnelykke, K., Torrent, M., Andersson, M., Sleiman, P., Hakonarson, H., Cookson, W. O., Moffatt, M. F., Paternoster, L., Melén, E., Sunyer, J., Bisgaard, H., Koppelman, G. H., Ege, M., Custovic, A., Heinrich, J., Gilliland, F. D., Henderson, A. J., Jaddoe, V. W. V., de Jongste, J. C., & EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium (2013). Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. Journal of Allergy and Clinical Immunology, 134(1), 46-55. doi:10.1016/j.jaci.2013.08.053.

    Abstract

    BACKGROUND: The fraction of exhaled nitric oxide (Feno) value is a biomarker of eosinophilic airway inflammation and is associated with childhood asthma. Identification of common genetic variants associated with childhood Feno values might help to define biological mechanisms related to specific asthma phenotypes.
    OBJECTIVE: We sought to identify the genetic variants associated with childhood Feno values and their relation with asthma.
    METHODS: Feno values were measured in children age 5 to 15 years. In 14 genome-wide association studies (N = 8,858), we examined the associations of approximately 2.5 million single nucleotide polymorphisms (SNPs) with Feno values. Subsequently, we assessed whether significant SNPs were expression quantitative trait loci in genome-wide expression data sets of lymphoblastoid cell lines (n = 1,830) and were related to asthma in a previously published genome-wide association data set (cases, n = 10,365; control subjects: n = 16,110).
    RESULTS: We identified 3 SNPs associated with Feno values: rs3751972 in LYR motif containing 9 (LYRM9; P = 1.97 × 10(-10)) and rs944722 in inducible nitric oxide synthase 2 (NOS2; P = 1.28 × 10(-9)), both of which are located at 17q11.2-q12, and rs8069176 near gasdermin B (GSDMB; P = 1.88 × 10(-8)) at 17q12-q21. We found a cis expression quantitative trait locus for the transcript soluble galactoside-binding lectin 9 (LGALS9) that is in linkage disequilibrium with rs944722. rs8069176 was associated with GSDMB and ORM1-like 3 (ORMDL3) expression. rs8069176 at 17q12-q21, but not rs3751972 and rs944722 at 17q11.2-q12, were associated with physician-diagnosed asthma.
    CONCLUSION: This study identified 3 variants associated with Feno values, explaining 0.95% of the variance. Identification of functional SNPs and haplotypes in these regions might provide novel insight into the regulation of Feno values. This study highlights that both shared and distinct genetic factors affect Feno values and childhood asthma.
  • Van Stekelenburg, J., Anikina, N. C., Pouw, W., Petrovic, I., & Nederlof, N. (2013). From correlation to causation: The cruciality of a collectivity in the context of collective action. Journal of Social and Political Psychology, 1(1), 161-187. doi:10.5964/jspp.v1i1.38.

    Abstract

    This paper discusses a longitudinal field study on collective action which aims to move beyond student samples and enhance mundane realism. First we provide a historical overview of the literature on the what (i.e., antecedents of collective action) and the how (i.e., the methods employed) of the social psychology of protest. This historical overview is substantiated with meta-analytical evidence on how these antecedents and methods changed over time. After the historical overview, we provide an empirical illustration of a longitudinal field study in a natural setting―a newly-built Dutch neighbourhood. We assessed changes in informal embeddedness, efficacy, identification, emotions, and grievances over time. Between t0 and t1 the residents protested against the plan to allow a mosque to carrying out their services in a community building in the neighbourhood. We examined the antecedents of protest before [t0] and after [t1] the protests, and whether residents participated or not. We show how a larger social network functions as a catalyst in steering protest participation. Our longitudinal field study replicates basic findings from experimental and survey research. However, it also shows that one antecedent in particular, which is hard to manipulate in the lab (i.e., the size of someone’s social network), proved to be of great importance. We suggest that in overcoming our most pertinent challenge―causality―we should not only remain in our laboratories but also go out and examine real-life situations with people situated in real-life social networks.
  • Van Wijk, C., & Kempen, G. (1985). From sentence structure to intonation contour: An algorithm for computing pitch contours on the basis of sentence accents and syntactic structure. In B. Müller (Ed.), Sprachsynthese: Zur Synthese von natürlich gesprochener Sprache aus Texten und Konzepten (pp. 157-182). Hildesheim: Georg Olms.
  • Van Berkum, J. J. A., De Goede, D., Van Alphen, P. M., Mulder, E. R., & Kerstholt, J. H. (2013). How robust is the language architecture? The case of mood. Frontiers in Psychology, 4: 505. doi:10.3389/fpsyg.2013.00505.

    Abstract

    In neurocognitive research on language, the processing principles of the system at hand are usually assumed to be relatively invariant. However, research on attention, memory, decision-making, and social judgment has shown that mood can substantially modulate how the brain processes information. For example, in a bad mood, people typically have a narrower focus of attention and rely less on heuristics. In the face of such pervasive mood effects elsewhere in the brain, it seems unlikely that language processing would remain untouched. In an EEG experiment, we manipulated the mood of participants just before they read texts that confirmed or disconfirmed verb-based expectations about who would be talked about next (e.g., that “David praised Linda because … ” would continue about Linda, not David), or that respected or violated a syntactic agreement rule (e.g., “The boys turns”). ERPs showed that mood had little effect on syntactic parsing, but did substantially affect referential anticipation: whereas readers anticipated information about a specific person when they were in a good mood, a bad mood completely abolished such anticipation. A behavioral follow-up experiment suggested that a bad mood did not interfere with verb-based expectations per se, but prevented readers from using that information rapidly enough to predict upcoming reference on the fly, as the sentence unfolds. In all, our results reveal that background mood, a rather unobtrusive affective state, selectively changes a crucial aspect of real-time language processing. This observation fits well with other observed interactions between language processing and affect (emotions, preferences, attitudes, mood), and more generally testifies to the importance of studying “cold” cognitive functions in relation to “hot” aspects of the brain.
  • Van den Bos, E., & Poletiek, F. H. (2008). Intentional artificial grammar learning: When does it work? European Journal of Cognitive Psychology, 20(4), 793-806. doi:10.1080/09541440701554474.

    Abstract

    Actively searching for the rules of an artificial grammar has often been shown to produce no more knowledge than memorising exemplars without knowing that they have been generated by a grammar. The present study investigated whether this ineffectiveness of intentional learning could be overcome by removing dual task demands and providing participants with more specific instructions. The results only showed a positive effect of learning intentionally for participants specifically instructed to find out which letters are allowed to follow each other. These participants were also unaffected by a salient feature. In contrast, for participants who did not know what kind of structure to expect, intentional learning was not more effective than incidental learning and knowledge acquisition was guided by salience.
  • Van Valin Jr., R. D. (2003). Minimalism and explanation. In J. Moore, & M. Polinsky (Eds.), The nature of explanation in linguistic theory (pp. 281-297). University of Chicago Press.
  • Van Valin Jr., R. D. (2013). Head-marking languages and linguistic theory. In B. Bickel, L. A. Grenoble, D. A. Peterson, & A. Timberlake (Eds.), Language typology and historical contingency: In honor of Johanna Nichols (pp. 91-124). Amsterdam: Benjamins.

    Abstract

    In her path-breaking 1986 paper, Johanna Nichols proposed a typological contrast between head-marking and dependent-marking languages. Nichols argues that even though the syntactic relations between the head and its dependents are the same in both types of language, the syntactic “bond” between them is not the same; in dependent-marking languages it is one of government, whereas in head-marking languages it is one of apposition. This distinction raises an important question for linguistic theory: How can this contrast – government versus apposition – which can show up in all of the major phrasal types in a language, be captured? The purpose of this paper is to explore the various approaches that have been taken in an attempt to capture the difference between head-marked and dependent-marked syntax in different linguistic theories. The basic problem that head-marking languages pose for syntactic theory will be presented, and then generative approaches will be discussed. The analysis of head-marked structure in Role and Reference Grammar will be presented
  • Van Valin Jr., R. D. (2013). Lexical representation, co-composition, and linking syntax and semantics. In J. Pustejovsky, P. Bouillon, H. Isahara, K. Kanzaki, & C. Lee (Eds.), Advances in generative lexicon theory (pp. 67-107). Dordrecht: Springer.
  • Van der Zande, P., Jesse, A., & Cutler, A. (2013). Lexically guided retuning of visual phonetic categories. Journal of the Acoustical Society of America, 134, 562-571. doi:10.1121/1.4807814.

    Abstract

    Listeners retune the boundaries between phonetic categories to adjust to individual speakers' productions. Lexical information, for example, indicates what an unusual sound is supposed to be, and boundary retuning then enables the speaker's sound to be included in the appropriate auditory phonetic category. In this study, it was investigated whether lexical knowledge that is known to guide the retuning of auditory phonetic categories, can also retune visual phonetic categories. In Experiment 1, exposure to a visual idiosyncrasy in ambiguous audiovisually presented target words in a lexical decision task indeed resulted in retuning of the visual category boundary based on the disambiguating lexical context. In Experiment 2 it was tested whether lexical information retunes visual categories directly, or indirectly through the generalization from retuned auditory phonetic categories. Here, participants were exposed to auditory-only versions of the same ambiguous target words as in Experiment 1. Auditory phonetic categories were retuned by lexical knowledge, but no shifts were observed for the visual phonetic categories. Lexical knowledge can therefore guide retuning of visual phonetic categories, but lexically guided retuning of auditory phonetic categories is not generalized to visual categories. Rather, listeners adjust auditory and visual phonetic categories to talker idiosyncrasies separately.
  • Van Geenhoven, V. (1998). On the Argument Structure of some Noun Incorporating Verbs in West Greenlandic. In M. Butt, & W. Geuder (Eds.), The Projection of Arguments - Lexical and Compositional Factors (pp. 225-263). Stanford, CA, USA: CSLI Publications.
  • Van Wingen, G. A., Van Broekhoven, F., Verkes, R. J., Petersson, K. M., Bäckström, T., Buitelaar, J. K., & Fernández, G. (2008). Progesterone selectively increases amygdala reactivity in women. Molecular Psychiatry, 13, 325-333. doi:doi:10.1038/sj.mp.4002030.

    Abstract

    The acute neural effects of progesterone are mediated by its neuroactive metabolites allopregnanolone and pregnanolone. These neurosteroids potentiate the inhibitory actions of c-aminobutyric acid (GABA). Progesterone is known to produce anxiolytic effects in animals, but recent animal studies suggest that pregnanolone increases anxiety after a period of low allopregnanolone concentration. This effect is potentially mediated by the amygdala and related to the negative mood symptoms in humans that are observed during increased allopregnanolone levels. Therefore, we investigated with functional magnetic resonance imaging (MRI) whether a single progesterone administration to healthy young women in their follicular phase modulates the amygdala response to salient, biologically relevant stimuli. The progesterone administration increased the plasma concentrations of progesterone and allopregnanolone to levels that are reached during the luteal phase and early pregnancy. The imaging results show that progesterone selectively increased amygdala reactivity. Furthermore, functional connectivity analyses indicate that progesterone modulated functional coupling of the amygdala with distant brain regions. These results reveal a neural mechanism by which progesterone may mediate adverse effects on anxiety and mood.
  • Van Leeuwen, T. M., Hagoort, P., & Händel, B. F. (2013). Real color captures attention and overrides spatial cues in grapheme-color synesthetes but not in controls. Neuropsychologia, 51(10), 1802-1813. doi:10.1016/j.neuropsychologia.2013.06.024.

    Abstract

    Grapheme-color synesthetes perceive color when reading letters or digits. We investigated oscillatory brain signals of synesthetes vs. controls using magnetoencephalography. Brain oscillations specifically in the alpha band (∼10 Hz) have two interesting features: alpha has been linked to inhibitory processes and can act as a marker for attention. The possible role of reduced inhibition as an underlying cause of synesthesia, as well as the precise role of attention in synesthesia is widely discussed. To assess alpha power effects due to synesthesia, synesthetes as well as matched controls viewed synesthesia-inducing graphemes, colored control graphemes, and non-colored control graphemes while brain activity was recorded. Subjects had to report a color change at the end of each trial which allowed us to assess the strength of synesthesia in each synesthete. Since color (synesthetic or real) might allocate attention we also included an attentional cue in our paradigm which could direct covert attention. In controls the attentional cue always caused a lateralization of alpha power with a contralateral decrease and ipsilateral alpha increase over occipital sensors. In synesthetes, however, the influence of the cue was overruled by color: independent of the attentional cue, alpha power decreased contralateral to the color (synesthetic or real). This indicates that in synesthetes color guides attention. This was confirmed by reaction time effects due to color, i.e. faster RTs for the color side independent of the cue. Finally, the stronger the observed color dependent alpha lateralization, the stronger was the manifestation of synesthesia as measured by congruency effects of synesthetic colors on RTs. Behavioral and imaging results indicate that color induces a location-specific, automatic shift of attention towards color in synesthetes but not in controls. We hypothesize that this mechanism can facilitate coupling of grapheme and color during the development of synesthesia.
  • Van Valin Jr., R. D. (1998). The acquisition of WH-questions and the mechanisms of language acquisition. In M. Tomasello (Ed.), The new psychology of language: Cognitive and functional approaches to language structure (pp. 221-249). Mahwah, New Jersey: Erlbaum.
  • Van de Geer, J. P., Levelt, W. J. M., & Plomp, R. (1962). The connotation of musical consonance. Acta Psychologica, 20, 308-319.

    Abstract

    As a preliminary to further research on musical consonance an explanatory investigation was made on the different modes of judgment of musical intervals. This was done by way of a semantic differential. Subjects rated 23 intervals against 10 scales. In a factor analysis three factors appeared: pitch, evaluation and fusion. The relation between these factors and some physical characteristics has been investigated. The scale consonant-dissonant showed to be purely evaluative (in opposition to Stumpf's theory). This evaluative connotation is not in accordance with the musicological meaning of consonance. Suggestions to account for this difference have been given.
  • Van Valin Jr., R. D. (2008). Some remarks on universal grammar. In J. Guo, E. Lieven, N. Budwig, S. Ervin-Tripp, K. Nakamura, & S. Ozcaliskan (Eds.), Crosslinguistic approaches to the psychology of language: Research in the tradition of Dan Isaac Slobin (pp. 311-320). New York: Psychology Press.
  • Van Valin Jr., R. D. (2008). RPs and the nature of lexical and syntactic categories in role and reference grammar. In R. D. Van Valin Jr. (Ed.), Investigations of the syntax-semantics-pragmatics interface (pp. 161-178). Amsterdam: Benjamins.
  • Van Geert, E., Ding, R., & Wagemans, J. (2024). A cross-cultural comparison of aesthetic preferences for neatly organized compositions: Native Chinese- versus Native Dutch-speaking samples. Empirical Studies of the Arts. Advance online publication. doi:10.1177/02762374241245917.

    Abstract

    Do aesthetic preferences for images of neatly organized compositions (e.g., images collected on blogs like Things Organized Neatly©) generalize across cultures? In an earlier study, focusing on stimulus and personal properties related to order and complexity, Western participants indicated their preference for one of two simultaneously presented images (100 pairs). In the current study, we compared the data of the native Dutch-speaking participants from this earlier sample (N = 356) to newly collected data from a native Chinese-speaking sample (N = 220). Overall, aesthetic preferences were quite similar across cultures. When relating preferences for each sample to ratings of order, complexity, soothingness, and fascination collected from a Western, mainly Dutch-speaking sample, the results hint at a cross-culturally consistent preference for images that Western participants rate as more ordered, but a cross-culturally diverse relation between preferences and complexity.
  • Van der Werff, J., Ravignani, A., & Jadoul, Y. (2024). thebeat: A Python package for working with rhythms and other temporal sequences. Behavior Research Methods, 56, 3725-3736. doi:10.3758/s13428-023-02334-8.

    Abstract

    thebeat is a Python package for working with temporal sequences and rhythms in the behavioral and cognitive sciences, as well as in bioacoustics. It provides functionality for creating experimental stimuli, and for visualizing and analyzing temporal data. Sequences, sounds, and experimental trials can be generated using single lines of code. thebeat contains functions for calculating common rhythmic measures, such as interval ratios, and for producing plots, such as circular histograms. thebeat saves researchers time when creating experiments, and provides the first steps in collecting widely accepted methods for use in timing research. thebeat is an open-source, on-going, and collaborative project, and can be extended for use in specialized subfields. thebeat integrates easily with the existing Python ecosystem, allowing one to combine our tested code with custom-made scripts. The package was specifically designed to be useful for both skilled and novice programmers. thebeat provides a foundation for working with temporal sequences onto which additional functionality can be built. This combination of specificity and plasticity should facilitate research in multiple research contexts and fields of study.
  • Vaughn, C., & Brouwer, S. (2013). Perceptual integration of indexical information in bilingual speech. Proceedings of Meetings on Acoustics, 19: 060208. doi:10.1121/1.4800264.

    Abstract

    The present research examines how different types of indexical information, namely talker information and the language being spoken, are perceptually integrated in bilingual speech. Using a speeded classification paradigm (Garner, 1974), variability in characteristics of the talker (gender in Experiment 1 and specific talker in Experiment 2) and in the language being spoken (Mandarin vs. English) was manipulated. Listeners from two different language backgrounds, English monolinguals and Mandarin-English bilinguals, were asked to classify short, meaningful sentences obtained from different Mandarin-English bilingual talkers on these indexical dimensions. Results for the gender-language classification (Exp. 1) showed a significant, symmetrical interference effect for both listener groups, indicating that gender information and language are processed in an integral manner. For talker-language classification (Exp. 2), language interfered more with talker than vice versa for the English monolinguals, but symmetrical interference was found for the Mandarin-English bilinguals. These results suggest both that talker-specificity is not fully segregated from language-specificity, and that bilinguals exhibit more balanced classification along various indexical dimensions of speech. Currently, follow-up studies investigate this talker-language dependency for bilingual listeners who do not speak Mandarin in order to disentangle the role of bilingualism versus language familiarity.
  • Verdonschot, R. G., La Heij, W., Tamaoka, K., Kiyama, S., You, W.-P., & Schiller, N. O. (2013). The multiple pronunciations of Japanese kanji: A masked priming investigation. Quarterly Journal of Experimental Psychology, 66(10), 2023-2038. doi:10.1080/17470218.2013.773050.

    Abstract

    English words with an inconsistent grapheme-to-phoneme conversion or with more than one pronunciation (homographic heterophones; e.g., lead-/l epsilon d/, /lid/) are read aloud more slowly than matched controls, presumably due to competition processes. In Japanese kanji, the majority of the characters have multiple readings for the same orthographic unit: the native Japanese reading (KUN) and the derived Chinese reading (ON). This leads to the question of whether reading these characters also shows processing costs. Studies examining this issue have provided mixed evidence. The current study addressed the question of whether processing of these kanji characters leads to the simultaneous activation of their KUN and ON reading, This was measured in a direct way in a masked priming paradigm. In addition, we assessed whether the relative frequencies of the KUN and ON pronunciations (dominance ratio, measured in compound words) affect the amount of priming. The results of two experiments showed that: (a) a single kanji, presented as a masked prime, facilitates the reading of the (katakana transcriptions of) their KUN and ON pronunciations; however, (b) this was most consistently found when the dominance ratio was around 50% (no strong dominance towards either pronunciation) and when the dominance was towards the ON reading (high-ON group). When the dominance was towards the KUN reading (high-KUN group), no significant priming for the ON reading was observed. Implications for models of kanji processing are discussed.
  • Verdonschot, R. G., Nakayama, M., Zhang, Q., Tamaoka, K., & Schiller, N. O. (2013). The proximate phonological unit of Chinese-English bilinguals: Proficiency matters. PLoS One, 8(4): e61454. doi:10.1371/journal.pone.0061454.

    Abstract

    An essential step to create phonology according to the language production model by Levelt, Roelofs and Meyer is to assemble phonemes into a metrical frame. However, recently, it has been proposed that different languages may rely on different grain sizes of phonological units to construct phonology. For instance, it has been proposed that, instead of phonemes, Mandarin Chinese uses syllables and Japanese uses moras to fill the metrical frame. In this study, we used a masked priming-naming task to investigate how bilinguals assemble their phonology for each language when the two languages differ in grain size. Highly proficient Mandarin Chinese-English bilinguals showed a significant masked onset priming effect in English (L2), and a significant masked syllabic priming effect in Mandarin Chinese (L1). These results suggest that their proximate unit is phonemic in L2 (English), and that bilinguals may use different phonological units depending on the language that is being processed. Additionally, under some conditions, a significant sub-syllabic priming effect was observed even in Mandarin Chinese, which indicates that L2 phonology exerts influences on L1 target processing as a consequence of having a good command of English.

    Additional information

    English stimuli Chinese stimuli
  • Verga, L., & Kotz, S. A. (2013). How relevant is social interaction in second language learning? Frontiers in Human Neuroscience, 7: 550. doi:10.3389/fnhum.2013.00550.

    Abstract

    Verbal language is the most widespread mode of human communication, and an intrinsically social activity. This claim is strengthened by evidence emerging from different fields, which clearly indicates that social interaction influences human communication, and more specifically, language learning. Indeed, research conducted with infants and children shows that interaction with a caregiver is necessary to acquire language. Further evidence on the influence of sociality on language comes from social and linguistic pathologies, in which deficits in social and linguistic abilities are tightly intertwined, as is the case for Autism, for example. However, studies on adult second language (L2) learning have been mostly focused on individualistic approaches, partly because of methodological constraints, especially of imaging methods. The question as to whether social interaction should be considered as a critical factor impacting upon adult language learning still remains underspecified. Here, we review evidence in support of the view that sociality plays a significant role in communication and language learning, in an attempt to emphasize factors that could facilitate this process in adult language learning. We suggest that sociality should be considered as a potentially influential factor in adult language learning and that future studies in this domain should explicitly target this factor.
  • Verhoef, E., Allegrini, A. G., Jansen, P. R., Lange, K., Wang, C. A., Morgan, A. T., Ahluwalia, T. S., Symeonides, C., EAGLE-Working Group, Eising, E., Franken, M.-C., Hypponen, E., Mansell, T., Olislagers, M., Omerovic, E., Rimfeld, K., Schlag, F., Selzam, S., Shapland, C. Y., Tiemeier, H., Whitehouse, A. J. O. Verhoef, E., Allegrini, A. G., Jansen, P. R., Lange, K., Wang, C. A., Morgan, A. T., Ahluwalia, T. S., Symeonides, C., EAGLE-Working Group, Eising, E., Franken, M.-C., Hypponen, E., Mansell, T., Olislagers, M., Omerovic, E., Rimfeld, K., Schlag, F., Selzam, S., Shapland, C. Y., Tiemeier, H., Whitehouse, A. J. O., Saffery, R., Bønnelykke, K., Reilly, S., Pennell, C. E., Wake, M., Cecil, C. A., Plomin, R., Fisher, S. E., & St Pourcain, B. (2024). Genome-wide analyses of vocabulary size in infancy and toddlerhood: Associations with Attention-Deficit/Hyperactivity Disorder and cognition-related traits. Biological Psychiatry, 95(1), 859-869. doi:10.1016/j.biopsych.2023.11.025.

    Abstract

    Background

    The number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta–genome-wide association study of vocabulary acquisition and investigated polygenic overlap with literacy, cognition, developmental phenotypes, and neurodevelopmental conditions, including attention-deficit/hyperactivity disorder (ADHD).

    Methods

    We studied 37,913 parent-reported vocabulary size measures (English, Dutch, Danish) for 17,298 children of European descent. Meta-analyses were performed for early-phase expressive (infancy, 15–18 months), late-phase expressive (toddlerhood, 24–38 months), and late-phase receptive (toddlerhood, 24–38 months) vocabulary. Subsequently, we estimated single nucleotide polymorphism–based heritability (SNP-h2) and genetic correlations (rg) and modeled underlying factor structures with multivariate models.

    Results

    Early-life vocabulary size was modestly heritable (SNP-h2 = 0.08–0.24). Genetic overlap between infant expressive and toddler receptive vocabulary was negligible (rg = 0.07), although each measure was moderately related to toddler expressive vocabulary (rg = 0.69 and rg = 0.67, respectively), suggesting a multifactorial genetic architecture. Both infant and toddler expressive vocabulary were genetically linked to literacy (e.g., spelling: rg = 0.58 and rg = 0.79, respectively), underlining genetic similarity. However, a genetic association of early-life vocabulary with educational attainment and intelligence emerged only during toddlerhood (e.g., receptive vocabulary and intelligence: rg = 0.36). Increased ADHD risk was genetically associated with larger infant expressive vocabulary (rg = 0.23). Multivariate genetic models in the ALSPAC (Avon Longitudinal Study of Parents and Children) cohort confirmed this finding for ADHD symptoms (e.g., at age 13; rg = 0.54) but showed that the association effect reversed for toddler receptive vocabulary (rg = −0.74), highlighting developmental heterogeneity.

    Conclusions

    The genetic architecture of early-life vocabulary changes during development, shaping polygenic association patterns with later-life ADHD, literacy, and cognition-related traits.
  • Verhoeven, L., Schreuder, R., & Baayen, R. H. (2003). Units of analysis in reading Dutch bisyllabic pseudowords. Scientific Studies of Reading, 7(3), 255-271. doi:10.1207/S1532799XSSR0703_4.

    Abstract

    Two experiments were carried out to explore the units of analysis is used by children to read Dutch bisyllabic pseudowords. Although Dutch orthography is highly regular, several deviations from a one-to-one correspondence occur. In polysyllabic words, the grapheme e may represent three different vowels:/∊/, /e/, or /λ/. In Experiment 1, Grade 6 elementary school children were presented lists of bisyllabic pseudowords containing the grapheme e in the initial syllable representing a content morpheme, a prefix, or a random string. On the basis of general word frequency data, we expected the interpretation of the initial syllable as a random string to elicit the pronunciation of a stressed /e/, the interpretation of the initial syllable as a content morpheme to elicit the pronunciation of a stressed /∊/, the interpretation of the initial syllable as a content morpheme to elicit the pronunciation of a stressed /∊/, and the interpretation as a prefix to elicit the pronunciation of an unstressed /&lamda;/. We found both the pronunciation and the stress assignment for pseudowords to depend on word type, which shows morpheme boundaries and prefixes to be identified. However, the identification of prefixes could also be explained by the correspondence of the prefix boundaries in the pseudowords to syllable boundaries. To exclude this alternative explanation, a follow-up experiment with the same group of children was conducted using bisyllabic pseudowords containing prefixes that did not coincide with syllable boundaries versus similar pseudowords with no prefix. The results of the first experiment were replicated. That is, the children identified prefixes and shifted their assignment of word stress accordingly. The results are discussed with reference to a parallel dual-route model of word decoding
  • Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., St Pourcain, B., Simpson, C. L., Mäkelä, K.-M., Lehtimäki, T. and 90 moreVerhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., St Pourcain, B., Simpson, C. L., Mäkelä, K.-M., Lehtimäki, T., Kähönen, M., Paterson, A. D., Hosseini, S. M., Wong, H. S., Xu, L., Jonas, J. B., Pärssinen, O., Wedenoja, J., Yip, S. P., Ho, D. W. H., Pang, C. P., Chen, L. J., Burdon, K. P., Craig, J. E., Klein, B. E. K., Klein, R., Haller, T., Metspalu, A., Khor, C.-C., Tai, E.-S., Aung, T., Vithana, E., Tay, W.-T., Barathi, V. A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R. T., Döring, A., Evans, D. M., Timpson, N. J., Verkerk, A. J. M. H., Meitinger, T., Raitakari, O., Hawthorne, F., Spector, T. D., Karssen, L. C., Pirastu, M., Murgia, F., Ang, W., Mishra, A., Montgomery, G. W., Pennell, C. E., Cumberland, P. M., Cotlarciuc, I., Mitchell, P., Wang, J. J., Schache, M., Janmahasatian, S., Janmahasathian, S., Igo, R. P., Lass, J. H., Chew, E., Iyengar, S. K., Gorgels, T. G. M. F., Rudan, I., Hayward, C., Wright, A. F., Polasek, O., Vatavuk, Z., Wilson, J. F., Fleck, B., Zeller, T., Mirshahi, A., Müller, C., Uitterlinden, A. G., Rivadeneira, F., Vingerling, J. R., Hofman, A., Oostra, B. A., Amin, N., Bergen, A. A. B., Teo, Y.-Y., Rahi, J. S., Vitart, V., Williams, C., Baird, P. N., Wong, T.-Y., Oexle, K., Pfeiffer, N., Mackey, D. A., Young, T. L., van Duijn, C. M., Saw, S.-M., Bailey-Wilson, J. E., Stambolian, D., Klaver, C. C., Hammond, C. J., Consortium for Refractive Error and Myopia (CREAM), The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Wellcome Trust Case Control Consortium 2 (WTCCC2), & The Fuchs' Genetics Multi-Center Study Group (2013). Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nature Genetics, 45(3), 314-318. doi:10.1038/ng.2554.

    Abstract

    Refractive error is the most common eye disorder worldwide and is a prominent cause of blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The CREAM consortium conducted genome-wide meta-analyses, including 37,382 individuals from 27 studies of European ancestry and 8,376 from 5 Asian cohorts. We identified 16 new loci for refractive error in individuals of European ancestry, of which 8 were shared with Asians. Combined analysis identified 8 additional associated loci. The new loci include candidate genes with functions in neurotransmission (GRIA4), ion transport (KCNQ5), retinoic acid metabolism (RDH5), extracellular matrix remodeling (LAMA2 and BMP2) and eye development (SIX6 and PRSS56). We also confirmed previously reported associations with GJD2 and RASGRF1. Risk score analysis using associated SNPs showed a tenfold increased risk of myopia for individuals carrying the highest genetic load. Our results, based on a large meta-analysis across independent multiancestry studies, considerably advance understanding of the mechanisms involved in refractive error and myopia.
  • Verkerk, A., & Lestrade, S. (2008). The encoding of adjectives. In M. Van Koppen, & B. Botma (Eds.), Linguistics in the Netherlands 2008 (pp. 157-168). Amsterdam: Benjamins.

    Abstract

    In this paper, we will give a unified account of the cross-linguistic variation in the encoding of adjectives in predicative and attributive constructions. Languages may differ in the encoding strategy of adjectives in the predicative domain (Stassen 1997), and sometimes change this strategy in the attributive domain (Verkerk 2007). We will show that the interaction of two principles, that of faithfulness to the semantic class of a lexical root and that of faithfulness to discourse functions, can account for all attested variation in the encoding of adjectives.
  • Verkerk, A., & Frostad, B. H. (2013). The encoding of manner predications and resultatives in Oceanic: A typological and historical overview. Oceanic Linguistics, 52, 1-35. doi:10.1353/ol.2013.0010.

    Abstract

    This paper is concerned with the encoding of resultatives and manner predications in Oceanic languages. Our point of departure is a typological overview of the encoding strategies and their geographical distribution, and we investigate their historical traits by the use of phylogenetic comparative methods. A full theory of the historical pathways is not always accessible for all the attested encoding strategies, given the data available for this study. However, tentative theories about the development and origin of the attested strategies are given. One of the most frequent strategy types used to encode both manner predications and resultatives has been given special emphasis. This is a construction in which a reex form of the Proto-Oceanic causative *pa-/*paka- modies the second verb in serial verb constructions

    Additional information

    52.1.verkerk_supp01.pdf
  • Verkerk, A. (2013). Scramble, scurry and dash: The correlation between motion event encoding and manner verb lexicon size in Indo-European. Language Dynamics and Change, 3, 169-217. doi:10.1163/22105832-13030202.

    Abstract

    In recent decades, much has been discovered about the different ways in which people can talk about motion (Talmy, 1985, 1991; Slobin, 1996, 1997, 2004). Slobin (1997) has suggested that satellite-framed languages typically have a larger and more diverse lexicon of manner of motion verbs (such as run, fly, and scramble) when compared to verb-framed languages. Slobin (2004) has claimed that larger manner of motion verb lexicons originate over time because codability factors increase the accessibility of manner in satellite-framed languages. In this paper I investigate the dependency between the use of the satellite-framed encoding construction and the size of the manner verb lexicon. The data used come from 20 Indo-European languages. The methodology applied is a range of phylogenetic comparative methods adopted from biology, which allow for an investigation of this dependency while taking into account the shared history between these 20 languages. The results provide evidence that Slobin’s hypothesis was correct, and indeed there seems to be a relationship between the use of the satellite-framed construction and the size of the manner verb lexicon
  • Vernes, S. C., Newbury, D. F., Abrahams, B. S., Winchester, L., Nicod, J., Groszer, M., Alarcón, M., Oliver, P. L., Davies, K. E., Geschwind, D. H., Monaco, A. P., & Fisher, S. E. (2008). A functional genetic link between distinct developmental language disorders. New England Journal of Medicine, 359(22), 2337 -2345. doi:10.1056/NEJMoa0802828.

    Abstract

    BACKGROUND: Rare mutations affecting the FOXP2 transcription factor cause a monogenic speech and language disorder. We hypothesized that neural pathways downstream of FOXP2 influence more common phenotypes, such as specific language impairment. METHODS: We performed genomic screening for regions bound by FOXP2 using chromatin immunoprecipitation, which led us to focus on one particular gene that was a strong candidate for involvement in language impairments. We then tested for associations between single-nucleotide polymorphisms (SNPs) in this gene and language deficits in a well-characterized set of 184 families affected with specific language impairment. RESULTS: We found that FOXP2 binds to and dramatically down-regulates CNTNAP2, a gene that encodes a neurexin and is expressed in the developing human cortex. On analyzing CNTNAP2 polymorphisms in children with typical specific language impairment, we detected significant quantitative associations with nonsense-word repetition, a heritable behavioral marker of this disorder (peak association, P=5.0x10(-5) at SNP rs17236239). Intriguingly, this region coincides with one associated with language delays in children with autism. CONCLUSIONS: The FOXP2-CNTNAP2 pathway provides a mechanistic link between clinically distinct syndromes involving disrupted language.

    Additional information

    nejm_vernes_2337sa1.pdf
  • Vernes, S. C., & Fisher, S. E. (2013). Genetic pathways implicated in speech and language. In S. Helekar (Ed.), Animal models of speech and language disorders (pp. 13-40). New York: Springer. doi:10.1007/978-1-4614-8400-4_2.

    Abstract

    Disorders of speech and language are highly heritable, providing strong
    support for a genetic basis. However, the underlying genetic architecture is complex,
    involving multiple risk factors. This chapter begins by discussing genetic loci associated
    with common multifactorial language-related impairments and goes on to
    detail the only gene (known as FOXP2) to be directly implicated in a rare monogenic
    speech and language disorder. Although FOXP2 was initially uncovered in
    humans, model systems have been invaluable in progressing our understanding of
    the function of this gene and its associated pathways in language-related areas of the
    brain. Research in species from mouse to songbird has revealed effects of this gene
    on relevant behaviours including acquisition of motor skills and learned vocalisations
    and demonstrated a role for Foxp2 in neuronal connectivity and signalling,
    particularly in the striatum. Animal models have also facilitated the identification of
    wider neurogenetic networks thought to be involved in language development and
    disorder and allowed the investigation of new candidate genes for disorders involving
    language, such as CNTNAP2 and FOXP1. Ongoing work in animal models promises
    to yield new insights into the genetic and neural mechanisms underlying human
    speech and language
  • Viaro, M., Bercelli, F., & Rossano, F. (2008). Una relazione terapeutica: Il terapeuta allenatore. Connessioni: Rivista di consulenza e ricerca sui sistemi umani, 20, 95-105.
  • Von Stutterheim, C., Carroll, M., & Klein, W. (2003). Two ways of construing complex temporal structures. In F. Lenz (Ed.), Deictic conceptualization of space, time and person (pp. 97-133). Amsterdam: Benjamins.
  • von Stutterheim, C., Flecken, M., & Carroll, M. (2013). Introduction: Conceptualizing in a second language. International Review of Applied Linguistics in Language Teaching, 51(2), 77-85. doi:10.1515/iral-2013-0004.
  • Vonk, W., & Cozijn, R. (2003). On the treatment of saccades and regressions in eye movement measures of reading time. In J. Hyönä, R. Radach, & H. Deubel (Eds.), The mind's eye: Cognitive and applied aspects of eye movement research (pp. 291-312). Amsterdam: Elsevier.
  • De Vos, C. (2008). Janger Kolok: de Balinese dovendans. Woord en Gebaar, 12-13.
  • De Vos, C. (2013). Sign-Spatiality in Kata Kolok: How a village sign language of Bali inscribes its signing space [Dissertation abstract]. Sign Language & Linguistics, 16(2), 277-284. doi:10.1075/sll.16.2.08vos.
  • De Vriend, F., Broeder, D., Depoorter, G., van Eerten, L., & Van Uytvanck, D. (2013). Creating & Testing CLARIN Metadata Components. Language Resources and Evaluation, 47(4), 1315-1326. doi:10.1007/s10579-013-9231-6.

    Abstract

    The CLARIN Metadata Infrastructure (CMDI) that is being developed in Common Language Resources and Technology Infrastructure (CLARIN) is a computer-supported framework that combines a flexible component approach with the explicit declaration of semantics. The goal of the Dutch CLARIN project “Creating & Testing CLARIN Metadata Components” was to create metadata components and profiles for a wide variety of existing resources housed at two data centres according to the CMDI specifications. In doing so the principles of the framework were tested. The results of the project are of benefit to other CLARIN-projects that are expected to adhere to the CMDI framework and its accompanying tools.
  • Wagensveld, B., Segers, E., Van Alphen, P. M., & Verhoeven, L. (2013). The role of lexical representations and phonological overlap in rhyme judgments of beginning, intermediate and advanced readers. Learning and Individual Differences, 23, 64-71. doi:10.1016/j.lindif.2012.09.007.

    Abstract

    Studies have shown that prereaders find globally similar non-rhyming pairs (i.e., bell–ball) difficult to judge. Although this effect has been explained as a result of ill-defined lexical representations, others have suggested that it is part of an innate tendency to respond to phonological overlap. In the present study we examined this effect over time. Beginning, intermediate and advanced readers were presented with a rhyme judgment task containing rhyming, phonologically similar, and unrelated non-rhyming pairs. To examine the role of lexical representations, participants were presented with both words and pseudowords. Outcomes showed that pseudoword processing was difficult for children but not for adults. The global similarity effect was present in both children and adults. The findings imply that holistic representations cannot explain the incapacity to ignore similarity relations during rhyming. Instead, the data provide more evidence for the idea that global similarity processing is part of a more fundamental innate phonological processing capacity.
  • Wagensveld, B., Van Alphen, P. M., Segers, E., Hagoort, P., & Verhoeven, L. (2013). The neural correlates of rhyme awareness in preliterate and literate children. Clinical Neurophysiology, 124, 1336-1345. doi:10.1016/j.clinph.2013.01.022.

    Abstract

    Objective Most rhyme awareness assessments do not encompass measures of the global similarity effect (i.e., children who are able to perform simple rhyme judgments get confused when presented with globally similar non-rhyming pairs). The present study examines the neural nature of this effect by studying the N450 rhyme effect. Methods Behavioral and electrophysiological responses of Dutch pre-literate kindergartners and literate second graders were recorded while they made rhyme judgments of word pairs in three conditions; phonologically rhyming (e.g., wijn-pijn), overlapping non-rhyming (e.g., pen-pijn) and unrelated non-rhyming pairs (e.g., boom-pijn). Results Behaviorally, both groups had difficulty judging overlapping but not rhyming and unrelated pairs. The neural data of second graders showed overlapping pairs were processed in a similar fashion as unrelated pairs; both showed a more negative deflection of the N450 component than rhyming items. Kindergartners did not show a typical N450 rhyme effect. However, some other interesting ERP differences were observed, indicating preliterates are sensitive to rhyme at a certain level. Significance Rhyme judgments of globally similar items rely on the same process as rhyme judgments of rhyming and unrelated items. Therefore, incorporating a globally similar condition in rhyme assessments may lead to a more in-depth measure of early phonological awareness skills. Highlights Behavioral and electrophysiological responses were recorded while (pre)literate children made rhyme judgments of rhyming, overlapping and unrelated words. Behaviorally both groups had difficulty judging overlapping pairs as non-rhyming while overlapping and unrelated neural patterns were similar in literates. Preliterates show a different pattern indicating a developing phonological system.
  • Wagner, A. (2013). Cross-language similarities and differences in the uptake of place information. Journal of the Acoustical Society of America, 133, 4256-4267. doi:10.1121/1.4802904.

    Abstract

    Cross-language differences in the use of coarticulatory cues for the identification of fricatives have been demonstrated in a phoneme detection task: Listeners with perceptually similar fricative pairs in their native phoneme inventories (English, Polish, Spanish) relied more on cues from vowels than listeners with perceptually more distinct fricative contrasts (Dutch and German). The present gating study further investigated these cross-language differences and addressed three questions. (1) Are there cross-language differences in informativeness of parts of the speech signal regarding place of articulation for fricative identification? (2) Are such cross-language differences fricative-specific, or do they extend to the perception of place of articulation for plosives? (3) Is such language-specific uptake of information based on cues preceding or following the consonantal constriction? Dutch, Italian, Polish, and Spanish listeners identified fricatives and plosives in gated CV and VC syllables. The results showed cross-language differences in the informativeness of coarticulatory cues for fricative identification: Spanish and Polish listeners extracted place of articulation information from shorter portions of VC syllables. No language-specific differences were found for plosives, suggesting that greater reliance on coarticulatory cues did not generalize to other phoneme types. The language-specific differences for fricatives were based on coarticulatory cues into the consonant.
  • Wagner, A., & Ernestus, M. (2008). Identification of phonemes: Differences between phoneme classes and the effect of class size. Phonetica, 65(1-2), 106-127. doi:10.1159/000132389.

    Abstract

    This study reports general and language-specific patterns in phoneme identification. In a series of phoneme monitoring experiments, Castilian Spanish, Catalan, Dutch, English, and Polish listeners identified vowel, fricative, and stop consonant targets that are phonemic in all these languages, embedded in nonsense words. Fricatives were generally identified more slowly than vowels, while the speed of identification for stop consonants was highly dependent on the onset of the measurements. Moreover, listeners' response latencies and accuracy in detecting a phoneme correlated with the number of categories within that phoneme's class in the listener's native phoneme repertoire: more native categories slowed listeners down and decreased their accuracy. We excluded the possibility that this effect stems from differences in the frequencies of occurrence of the phonemes in the different languages. Rather, the effect of the number of categories can be explained by general properties of the perception system, which cause language-specific patterns in speech processing.
  • Waller, D., & Haun, D. B. M. (2003). Scaling techniques for modeling directional knowledge. Behavior Research Methods, Instruments, & Computers, 35(2), 285-293.

    Abstract

    A common way for researchers to model or graphically portray spatial knowledge of a large environment is by applying multidimensional scaling (MDS) to a set of pairwise distance estimations. We introduce two MDS-like techniques that incorporate people’s knowledge of directions instead of (or in addition to) their knowledge of distances. Maps of a familiar environment derived from these procedures were more accurate and were rated by participants as being more accurate than those derived from nonmetric MDS. By incorporating people’s relatively accurate knowledge of directions, these methods offer spatial cognition researchers and behavioral geographers a sharper analytical tool than MDS for studying cognitive maps.
  • Walters, J., Rujescu, D., Franke, B., Giegling, I., Vasquez, A., Hargreaves, A., Russo, G., Morris, D., Hoogman, M., Da Costa, A., Moskvina, V., Fernandez, G., Gill, M., Corvin, A., O'Donovan, M., Donohoe, G., & Owen, M. (2013). The role of the major histocompatibility complex region in cognition and brain structure: A schizophrenia GWAS follow-up. American Journal of Psychiatry, 170, 877-885. doi:10.1176/appi.ajp.2013.12020226.

    Abstract

    Objective The authors investigated the effects of recently identified genome-wide significant schizophrenia genetic risk variants on cognition and brain structure. Method A panel of six single-nucleotide polymorphisms (SNPs) was selected to represent genome-wide significant loci from three recent genome-wide association studies (GWAS) for schizophrenia and was tested for association with cognitive measures in 346 patients with schizophrenia and 2,342 healthy comparison subjects. Nominally significant results were evaluated for replication in an independent case-control sample. For SNPs showing evidence of association with cognition, associations with brain structural volumes were investigated in a large independent healthy comparison sample. Results Five of the six SNPs showed no significant association with any cognitive measure. One marker in the major histocompatibility complex (MHC) region, rs6904071, showed independent, replicated evidence of association with delayed episodic memory and was significant when both samples were combined. In the combined sample of up to 3,100 individuals, this SNP was associated with widespread effects across cognitive domains, although these additional associations were no longer significant after adjusting for delayed episodic memory. In the large independent structural imaging sample, the same SNP was also associated with decreased hippocampal volume. Conclusions The authors identified a SNP in the MHC region that was associated with cognitive performance in patients with schizophrenia and healthy comparison subjects. This SNP, rs6904071, showed a replicated association with episodic memory and hippocampal volume. These findings implicate the MHC region in hippocampal structure and functioning, consistent with the role of MHC proteins in synaptic development and function. Follow-up of these results has the potential to provide insights into the pathophysiology of schizophrenia and cognition.

    Additional information

    Hoogman_2013_JourAmePsy.supp.pdf
  • Wang, L., Bastiaansen, M. C. M., Yang, Y., & Hagoort, P. (2013). ERP evidence on the interaction between information structure and emotional salience of words. Cognitive, Affective and Behavioral Neuroscience, 13, 297-310. doi:10.3758/s13415-012-0146-2.

    Abstract

    Both emotional words and words focused by information structure can capture attention. This study examined the interplay between emotional salience and information structure in modulating attentional resources in the service of integrating emotional words into sentence context. Event-related potentials (ERPs) to affectively negative, neutral, and positive words, which were either focused or nonfocused in question–answer pairs, were evaluated during sentence comprehension. The results revealed an early negative effect (90–200 ms), a P2 effect, as well as an effect in the N400 time window, for both emotional salience and information structure. Moreover, an interaction between emotional salience and information structure occurred within the N400 time window over right posterior electrodes, showing that information structure influences the semantic integration only for neutral words, but not for emotional words. This might reflect the fact that the linguistic salience of emotional words can override the effect of information structure on the integration of words into context. The interaction provides evidence for attention–emotion interactions at a later stage of processing. In addition, the absence of interaction in the early time window suggests that the processing of emotional information is highly automatic and independent of context. The results suggest independent attention capture systems of emotional salience and information structure at the early stage but an interaction between them at a later stage, during the semantic integration of words.
  • Wang, L., Zhu, Z., Bastiaansen, M. C. M., Hagoort, P., & Yang, Y. (2013). Recognizing the emotional valence of names: An ERP study. Brain and Language, 125, 118-127. doi:10.1016/j.bandl.2013.01.006.

    Abstract

    Unlike common nouns, person names refer to unique entities and generally have a referring function. We used event-related potentials to investigate the time course of identifying the emotional meaning of nouns and names. The emotional valence of names and nouns were manipulated separately. The results show early N1 effects in response to emotional valence only for nouns. This might reflect automatic attention directed towards emotional stimuli. The absence of such an effect for names supports the notion that the emotional meaning carried by names is accessed after word recognition and person identification. In addition, both names with negative valence and emotional nouns elicited late positive effects, which have been associated with evaluation of emotional significance. This positive effect started earlier for nouns than for names, but with similar durations. Our results suggest that distinct neural systems are involved in the retrieval of names’ and nouns’ emotional meaning.
  • Wang, L., & Chu, M. (2013). The role of beat gesture and pitch accent in semantic processing: An ERP study. Neuropsychologia, 51(13), 2847-2855. doi:10.1016/j.neuropsychologia.2013.09.027.

    Abstract

    The present study investigated whether and how beat gesture (small baton-like hand movements used to emphasize information in speech) influences semantic processing as well as its interaction with pitch accent during speech comprehension. Event-related potentials were recorded as participants watched videos of a person gesturing and speaking simultaneously. The critical words in the spoken sentences were accompanied by a beat gesture, a control hand movement, or no hand movement, and were expressed either with or without pitch accent. We found that both beat gesture and control hand movement induced smaller negativities in the N400 time window than when no hand movement was presented. The reduced N400s indicate that both beat gesture and control movement facilitated the semantic integration of the critical word into the sentence context. In addition, the words accompanied by beat gesture elicited smaller negativities in the N400 time window than those accompanied by control hand movement over right posterior electrodes, suggesting that beat gesture has a unique role for enhancing semantic processing during speech comprehension. Finally, no interaction was observed between beat gesture and pitch accent, indicating that they affect semantic processing independently.
  • Wang, M.-Y., Korbmacher, M., Eikeland, R., Craven, A. R., & Specht, K. (2024). The intra‐individual reliability of1H‐MRSmeasurement in the anterior cingulate cortex across 1 year. Human Brain Mapping, 45(1): e26531. doi:10.1002/hbm.26531.

    Abstract

    Magnetic resonance spectroscopy (MRS) is the primary method that can measure the levels of metabolites in the brain in vivo. To achieve its potential in clinical usage, the reliability of the measurement requires further articulation. Although there are many studies that investigate the reliability of gamma-aminobutyric acid (GABA), comparatively few studies have investigated the reliability of other brain metabolites, such as glutamate (Glu), N-acetyl-aspartate (NAA), creatine (Cr), phosphocreatine (PCr), or myo-inositol (mI), which all play a significant role in brain development and functions. In addition, previous studies which predominately used only two measurements (two data points) failed to provide the details of the time effect (e.g., time-of-day) on MRS measurement within subjects. Therefore, in this study, MRS data located in the anterior cingulate cortex (ACC) were repeatedly recorded across 1 year leading to at least 25 sessions for each subject with the aim of exploring the variability of other metabolites by using the index coefficient of variability (CV); the smaller the CV, the more reliable the measurements. We found that the metabolites of NAA, tNAA, and tCr showed the smallest CVs (between 1.43% and 4.90%), and the metabolites of Glu, Glx, mI, and tCho showed modest CVs (between 4.26% and 7.89%). Furthermore, we found that the concentration reference of the ratio to water results in smaller CVs compared to the ratio to tCr. In addition, we did not find any time-of-day effect on the MRS measurements. Collectively, the results of this study indicate that the MRS measurement is reasonably reliable in quantifying the levels of metabolites.

    Additional information

    tables and figures data
  • Wang, X., Jahagirdar, S., Bakker, W., Lute, C., Kemp, B., Knegsel, A. v., & Saccenti, E. (2024). Discrimination of Lipogenic or Glucogenic Diet Effects in Early-Lactation Dairy Cows Using Plasma Metabolite Abundances and Ratios in Combination with Machine Learning. Metabolites, 14(4): 230. doi:10.3390/metabo14040230.

    Abstract

    During early lactation, dairy cows have a negative energy balance since their energy demands exceed their energy intake: in this study, we aimed to investigate the association between diet and plasma metabolomics profiles and how these relate to energy unbalance of course in the early-lactation stage. Holstein-Friesian cows were randomly assigned to a glucogenic (n = 15) or lipogenic (n = 15) diet in early lactation. Blood was collected in week 2 and week 4 after calving. Plasma metabolite profiles were detected using liquid chromatography–mass spectrometry (LC-MS), and a total of 39 metabolites were identified. Two plasma metabolomic profiles were available every week for each cow. Metabolite abundance and metabolite ratios were used for the analysis using the XGboost algorithm to discriminate between diet treatment and lactation week. Using metabolite ratios resulted in better discrimination performance compared with the metabolite abundances in assigning cows to a lipogenic diet or a glucogenic diet. The quality of the discrimination of performance of lipogenic diet and glucogenic diet effects improved from 0.606 to 0.753 and from 0.696 to 0.842 in week 2 and week 4 (as measured by area under the curve, AUC), when the metabolite abundance ratios were used instead of abundances. The top discriminating ratios for diet were the ratio of arginine to tyrosine and the ratio of aspartic acid to valine in week 2 and week 4, respectively. For cows fed the lipogenic diet, choline and the ratio of creatinine to tryptophan were top features to discriminate cows in week 2 vs. week 4. For cows fed the glucogenic diet, methionine and the ratio of 4-hydroxyproline to choline were top features to discriminate dietary effects in week 2 or week 4. This study shows the added value of using metabolite abundance ratios to discriminate between lipogenic and glucogenic diet and lactation weeks in early-lactation cows when using metabolomics data. The application of this research will help to accurately regulate the nutrition of lactating dairy cows and promote sustainable agricultural development.
  • Warmelink, L., Vrij, A., Mann, S., Leal, S., & Poletiek, F. H. (2013). The effects of unexpected questions on detecting familiar and unfamiliar lies. Psychiatry, Psychology and law, 20(1), 29-35. doi:10.1080/13218719.2011.619058.

    Abstract

    Previous research suggests that lie detection can be improved by asking the interviewee unexpected questions. The present experiment investigates the effect of two types of unexpected questions: background questions and detail questions, on detecting lies about topics with which the interviewee is (a) familiar or (b) unfamiliar. In this experiment, 66 participants read interviews in which interviewees answered background or detail questions, either truthfully or deceptively. Those who answered deceptively could be lying about a topic they were familiar with or about a topic they were unfamiliar with. The participants were asked to judge whether the interviewees were lying. The results revealed that background questions distinguished truths from both types of lies, while the detail questions distinguished truths from unfamiliar lies, but not from familiar lies. The implications of these findings are discussed.
  • Warner, N. (2003). Rapid perceptibility as a factor underlying universals of vowel inventories. In A. Carnie, H. Harley, & M. Willie (Eds.), Formal approaches to function in grammar, in honor of Eloise Jelinek (pp. 245-261). Amsterdam: Benjamins.
  • Weber, A., & Cutler, A. (2003). Perceptual similarity co-existing with lexical dissimilarity [Abstract]. Abstracts of the 146th Meeting of the Acoustical Society of America. Journal of the Acoustical Society of America, 114(4 Pt. 2), 2422. doi:10.1121/1.1601094.

    Abstract

    The extreme case of perceptual similarity is indiscriminability, as when two second‐language phonemes map to a single native category. An example is the English had‐head vowel contrast for Dutch listeners; Dutch has just one such central vowel, transcribed [E]. We examine whether the failure to discriminate in phonetic categorization implies indiscriminability in other—e.g., lexical—processing. Eyetracking experiments show that Dutch‐native listeners instructed in English to ‘‘click on the panda’’ look (significantly more than native listeners) at a pictured pencil, suggesting that pan‐ activates their lexical representation of pencil. The reverse, however, is not the case: ‘‘click on the pencil’’ does not induce looks to a panda, suggesting that pen‐ does not activate panda in the lexicon. Thus prelexically undiscriminated second‐language distinctions can nevertheless be maintained in stored lexical representations. The problem of mapping a resulting unitary input to two distinct categories in lexical representations is solved by allowing input to activate only one second‐language category. For Dutch listeners to English, this is English [E], as a result of which no vowels in the signal ever map to words containing [ae]. We suggest that the choice of category is here motivated by a more abstract, phonemic, metric of similarity.
  • Weber, K., & Lavric, A. (2008). Syntactic anomaly elicits a lexico-semantic (N400) ERP effect in the second but not in the first language. Psychophysiology, 45(6), 920-925. doi:10.1111/j.1469-8986.2008.00691.x.

    Abstract

    Recent brain potential research into first versus second language (L1 vs. L2) processing revealed striking responses to morphosyntactic features absent in the mother tongue. The aim of the present study was to establish whether the presence of comparable morphosyntactic features in L1 leads to more similar electrophysiological L1 and L2 profiles. ERPs were acquired while German-English bilinguals and native speakers of English read sentences. Some sentences were meaningful and well formed, whereas others contained morphosyntactic or semantic violations in the final word. In addition to the expected P600 component, morphosyntactic violations in L2 but not L1 led to an enhanced N400. This effect may suggest either that resolution of morphosyntactic anomalies in L2 relies on the lexico-semantic system or that the weaker/slower morphological mechanisms in L2 lead to greater sentence wrap-up difficulties known to result in N400 enhancement.
  • Weber, A. (2008). What eye movements can tell us about spoken-language processing: A psycholinguistic survey. In C. M. Riehl (Ed.), Was ist linguistische Evidenz: Kolloquium des Zentrums Sprachenvielfalt und Mehrsprachigkeit, November 2006 (pp. 57-68). Aachen: Shaker.
  • Wender, K. F., Haun, D. B. M., Rasch, B. H., & Blümke, M. (2003). Context effects in memory for routes. In C. Freksa, W. Brauer, C. Habel, & K. F. Wender (Eds.), Spatial cognition III: Routes and navigation, human memory and learning, spatial representation and spatial learning (pp. 209-231). Berlin: Springer.
  • Wesseldijk, L. W., Henechowicz, T. L., Baker, D. J., Bignardi, G., Karlsson, R., Gordon, R. L., Mosing, M. A., Ullén, F., & Fisher, S. E. (2024). Notes from Beethoven’s genome. Current Biology, 34(6), R233-R234. doi:10.1016/j.cub.2024.01.025.

    Abstract

    Rapid advances over the last decade in DNA sequencing and statistical genetics enable us to investigate the genomic makeup of individuals throughout history. In a recent notable study, Begg et al.1 used Ludwig van Beethoven’s hair strands for genome sequencing and explored genetic predispositions for some of his documented medical issues. Given that it was arguably Beethoven’s skills as a musician and composer that made him an iconic figure in Western culture, we here extend the approach and apply it to musicality. We use this as an example to illustrate the broader challenges of individual-level genetic predictions.

    Additional information

    supplemental information
  • Wheeldon, L. (2003). Inhibitory from priming of spoken word production. Language and Cognitive Processes, 18(1), 81-109. doi:10.1080/01690960143000470.

    Abstract

    Three experiments were designed to examine the effect on picture naming of the prior production of a word related in phonological form. In Experiment 1, the latency to produce Dutch words in response to pictures (e.g., hoed , hat) was longer following the production of a form-related word (e.g., hond , dog) in response to a definition on a preceding trial, than when the preceding definition elicited an unrelated word (e.g., kerk , church). Experiment 2 demonstrated that the inhibitory effect disappears when one unrelated word is produced intervening prime and target productions (e.g., hond-kerk-hoed ). The size of the inhibitory effect was not significantly affected by the frequency of the prime words or the target picture names. In Experiment 3, facilitation was observed for word pairs that shared offset segments (e.g., kurk-jurk , cork-dress), whereas inhibition was observed for shared onset segments (e.g., bloed-bloem , blood-flower). However, no priming was observed for prime and target words with shared phonemes but no mismatching segments (e.g., oom-boom , uncle-tree; hex-hexs , fence-witch). These findings are consistent with a process of phoneme competition during phonological encoding.
  • Whitmarsh, S., Udden, J., Barendregt, H., & Petersson, K. M. (2013). Mindfulness reduces habitual responding based on implicit knowledge: Evidence from artificial grammar learning. Consciousness and Cognition, (3), 833-845. doi:10.1016/j.concog.2013.05.007.

    Abstract

    Participants were unknowingly exposed to complex regularities in a working memory task. The existence of implicit knowledge was subsequently inferred from a preference for stimuli with similar grammatical regularities. Several affective traits have been shown to influence
    AGL performance positively, many of which are related to a tendency for automatic responding. We therefore tested whether the mindfulness trait predicted a reduction of grammatically congruent preferences, and used emotional primes to explore the influence of affect. Mindfulness was shown to correlate negatively with grammatically congruent responses. Negative primes were shown to result in faster and more negative evaluations.
    We conclude that grammatically congruent preference ratings rely on habitual responses, and that our findings provide empirical evidence for the non-reactive disposition of the mindfulness trait.
  • Widlok, T., Rapold, C. J., & Hoymann, G. (2008). Multimedia analysis in documentation projects: Kinship, interrogatives and reciprocals in ǂAkhoe Haiǁom. In K. D. Harrison, D. S. Rood, & A. Dwyer (Eds.), Lessons from documented endangered languages (pp. 355-370). Amsterdam: Benjamins.

    Abstract

    This contribution emphasizes the role of multimedia data not only for archiving languages but also for creating opportunities for innovative analyses. In the case at hand, video material was collected as part of the documentation of Akhoe Haiom, a Khoisan language spoken in northern Namibia. The multimedia documentation project brought together linguistic and anthropological work to highlight connections between specialized domains, namely kinship terminology, interrogatives and reciprocals. These connections would have gone unnoticed or undocumented in more conventional modes of language description. It is suggested that such an approach may be particularly appropriate for the documentation of endangered languages since it directs the focus of attention away from isolated traits of languages towards more complex practices of communication that are also frequently threatened with extinction.
  • Widlok, T. (2008). Landscape unbounded: Space, place, and orientation in ≠Akhoe Hai// om and beyond. Language Sciences, 30(2/3), 362-380. doi:10.1016/j.langsci.2006.12.002.

    Abstract

    Even before it became a common place to assume that “the Eskimo have a hundred words for snow” the languages of hunting and gathering people have played an important role in debates about linguistic relativity concerning geographical ontologies. Evidence from languages of hunter-gatherers has been used in radical relativist challenges to the overall notion of a comparative typology of generic natural forms and landscapes as terms of reference. It has been invoked to emphasize a personalized relationship between humans and the non-human world. It is against this background that this contribution discusses the landscape terminology of ≠Akhoe Hai//om, a Khoisan language spoken by “Bushmen” in Namibia. Landscape vocabulary is ubiquitous in ≠Akhoe Hai//om due to the fact that the landscape plays a critical role in directionals and other forms of “topographical gossip” and due to merges between landscape and group terminology. This system of landscape-cum-group terminology is outlined and related to the use of place names in the area.
  • Widlok, T. (2008). The dilemmas of walking: A comparative view. In T. Ingold, & J. L. Vergunst (Eds.), Ways of walking: Ethnography and practice on foot (pp. 51-66). Aldershot: Ashgate.
  • Willems, R. M., Ozyurek, A., & Hagoort, P. (2008). Seeing and hearing meaning: ERP and fMRI evidence of word versus picture integration into a sentence context. Journal of Cognitive Neuroscience, 20, 1235-1249. doi:10.1162/jocn.2008.20085.

    Abstract

    Understanding language always occurs within a situational context and, therefore, often implies combining streams of information from different domains and modalities. One such combination is that of spoken language and visual information, which are perceived together in a variety of ways during everyday communication. Here we investigate whether and how words and pictures differ in terms of their neural correlates when they are integrated into a previously built-up sentence context. This is assessed in two experiments looking at the time course (measuring event-related potentials, ERPs) and the locus (using functional magnetic resonance imaging, fMRI) of this integration process. We manipulated the ease of semantic integration of word and/or picture to a previous sentence context to increase the semantic load of processing. In the ERP study, an increased semantic load led to an N400 effect which was similar for pictures and words in terms of latency and amplitude. In the fMRI study, we found overlapping activations to both picture and word integration in the left inferior frontal cortex. Specific activations for the integration of a word were observed in the left superior temporal cortex. We conclude that despite obvious differences in representational format, semantic information coming from pictures and words is integrated into a sentence context in similar ways in the brain. This study adds to the growing insight that the language system incorporates (semantic) information coming from linguistic and extralinguistic domains with the same neural time course and by recruitment of overlapping brain areas.
  • Willems, R. M. (2013). Can literary studies contribute to cognitive neuroscience? Journal of literary semantics, 42(2), 217-222. doi:10.1515/jls-2013-0011.
  • Willems, R. M., Oostenveld, R., & Hagoort, P. (2008). Early decreases in alpha and gamma band power distinguish linguistic from visual information during spoken sentence comprehension. Brain Research, 1219, 78-90. doi:10.1016/j.brainres.2008.04.065.

    Abstract

    Language is often perceived together with visual information. This raises the question on how the brain integrates information conveyed in visual and/or linguistic format during spoken language comprehension. In this study we investigated the dynamics of semantic integration of visual and linguistic information by means of time-frequency analysis of the EEG signal. A modified version of the N400 paradigm with either a word or a picture of an object being semantically incongruous with respect to the preceding sentence context was employed. Event-Related Potential (ERP) analysis showed qualitatively similar N400 effects for integration of either word or picture. Time-frequency analysis revealed early specific decreases in alpha and gamma band power for linguistic and visual information respectively. We argue that these reflect a rapid context-based analysis of acoustic (word) or visual (picture) form information. We conclude that although full semantic integration of linguistic and visual information occurs through a common mechanism, early differences in oscillations in specific frequency bands reflect the format of the incoming information and, importantly, an early context-based detection of its congruity with respect to the preceding language context
  • Williams, N. M., Williams, H., Majounie, E., Norton, N., Glaser, B., Morris, H. R., Owen, M. J., & O'Donovan, M. C. (2008). Analysis of copy number variation using quantitative interspecies competitive PCR. Nucleic Acids Research, 36(17): e112. doi:10.1093/nar/gkn495.

    Abstract

    Over recent years small submicroscopic DNA copy-number variants (CNVs) have been highlighted as an important source of variation in the human genome, human phenotypic diversity and disease susceptibility. Consequently, there is a pressing need for the development of methods that allow the efficient, accurate and cheap measurement of genomic copy number polymorphisms in clinical cohorts. We have developed a simple competitive PCR based method to determine DNA copy number which uses the entire genome of a single chimpanzee as a competitor thus eliminating the requirement for competitive sequences to be synthesized for each assay. This results in the requirement for only a single reference sample for all assays and dramatically increases the potential for large numbers of loci to be analysed in multiplex. In this study we establish proof of concept by accurately detecting previously characterized mutations at the PARK2 locus and then demonstrating the potential of quantitative interspecies competitive PCR (qicPCR) to accurately genotype CNVs in association studies by analysing chromosome 22q11 deletions in a sample of previously characterized patients and normal controls.
  • Windhouwer, M., Petro, J., Newskaya, I., Drude, S., Aristar-Dry, H., & Gippert, J. (2013). Creating a serialization of LMF: The experience of the RELISH project. In G. Francopoulo (Ed.), LMF - Lexical Markup Framework (pp. 215-226). London: Wiley.
  • Windhouwer, M., & Wright, S. E. (2013). LMF and the Data Category Registry: Principles and application. In G. Francopoulo (Ed.), LMF: Lexical Markup Framework (pp. 41-50). London: Wiley.
  • Winter, B., Lupyan, G., Perry, L. K., Dingemanse, M., & Perlman, M. (2024). Iconicity ratings for 14,000+ English words. Behavior Research Methods, 56, 1640-1655. doi:10.3758/s13428-023-02112-6.

    Abstract

    Iconic words and signs are characterized by a perceived resemblance between aspects of their form and aspects of their meaning. For example, in English, iconic words include peep and crash, which mimic the sounds they denote, and wiggle and zigzag, which mimic motion. As a semiotic property of words and signs, iconicity has been demonstrated to play a role in word learning, language processing, and language evolution. This paper presents the results of a large-scale norming study for more than 14,000 English words conducted with over 1400 American English speakers. We demonstrate the utility of these ratings by replicating a number of existing findings showing that iconicity ratings are related to age of acquisition, sensory modality, semantic neighborhood density, structural markedness, and playfulness. We discuss possible use cases and limitations of the rating dataset, which is made publicly available.
  • Witteman, M. J., Weber, A., & McQueen, J. M. (2013). Foreign accent strength and listener familiarity with an accent co-determine speed of perceptual adaptation. Attention, Perception & Psychophysics, 75, 537-556. doi:10.3758/s13414-012-0404-y.

    Abstract

    We investigated how the strength of a foreign accent and varying types of experience with foreign-accented speech influence the recognition of accented words. In Experiment 1, native Dutch listeners with limited or extensive prior experience with German-accented Dutch completed a cross-modal priming experiment with strongly, medium, and weakly accented words. Participants with limited experience were primed by the medium and weakly accented words, but not by the strongly accented words. Participants with extensive experience were primed by all accent types. In Experiments 2 and 3, Dutch listeners with limited experience listened to a short story before doing the cross-modal priming task. In Experiment 2, the story was spoken by the priming task speaker and either contained strongly accented words or did not. Strongly accented exposure led to immediate priming by novel strongly accented words, while exposure to the speaker without strongly accented tokens led to priming only in the experiment’s second half. In Experiment 3, listeners listened to the story with strongly accented words spoken by a different German-accented speaker. Listeners were primed by the strongly accented words, but again only in the experiment’s second half. Together, these results show that adaptation to foreign-accented speech is rapid but depends on accent strength and on listener familiarity with those strongly accented words.
  • Wittenburg, P. (2003). The DOBES model of language documentation. Language Documentation and Description, 1, 122-139.
  • Wittenburg, P. (2008). Die CLARIN Forschungsinfrastruktur. ÖGAI-journal (Österreichische Gesellschaft für Artificial Intelligence), 27, 10-17.
  • Wittenburg, P., & Ringersma, J. (2013). Metadata description for lexicons. In R. H. Gouws, U. Heid, W. Schweickard, & H. E. Wiegand (Eds.), Dictionaries: An international encyclopedia of lexicography: Supplementary volume: Recent developments with focus on electronic and computational lexicography (pp. 1329-1335). Berlin: Mouton de Gruyter.
  • Wolna, A., Szewczyk, J., Diaz, M., Domagalik, A., Szwed, M., & Wodniecka, Z. (2024). Domain-general and language-specific contributions to speech production in a second language: An fMRI study using functional localizers. Scientific Reports, 14: 57. doi:10.1038/s41598-023-49375-9.

    Abstract

    For bilinguals, speaking in a second language (L2) compared to the native language (L1) is usually more difficult. In this study we asked whether the difficulty in L2 production reflects increased demands imposed on domain-general or core language mechanisms. We compared the brain response to speech production in L1 and L2 within two functionally-defined networks in the brain: the Multiple Demand (MD) network and the language network. We found that speech production in L2 was linked to a widespread increase of brain activity in the domain-general MD network. The language network did not show a similarly robust differences in processing speech in the two languages, however, we found increased response to L2 production in the language-specific portion of the left inferior frontal gyrus (IFG). To further explore our results, we have looked at domain-general and language-specific response within the brain structures postulated to form a Bilingual Language Control (BLC) network. Within this network, we found a robust increase in response to L2 in the domain-general, but also in some language-specific voxels including in the left IFG. Our findings show that L2 production strongly engages domain-general mechanisms, but only affects language sensitive portions of the left IFG. These results put constraints on the current model of bilingual language control by precisely disentangling the domain-general and language-specific contributions to the difficulty in speech production in L2.

    Additional information

    supplementary materials
  • Wolna, A., Szewczyk, J., Diaz, M., Domagalik, A., Szwed, M., & Wodniecka, Z. (2024). Tracking components of bilingual language control in speech production: An fMRI study using functional localizers. Neurobiology of Language, 5(2), 315-340. doi:10.1162/nol_a_00128.

    Abstract

    When bilingual speakers switch back to speaking in their native language (L1) after having used their second language (L2), they often experience difficulty in retrieving words in their L1. This phenomenon is referred to as the L2 after-effect. We used the L2 after-effect as a lens to explore the neural bases of bilingual language control mechanisms. Our goal was twofold: first, to explore whether bilingual language control draws on domain-general or language-specific mechanisms; second, to investigate the precise mechanism(s) that drive the L2 after-effect. We used a precision fMRI approach based on functional localizers to measure the extent to which the brain activity that reflects the L2 after-effect overlaps with the language network (Fedorenko et al., 2010) and the domain-general multiple demand network (Duncan, 2010), as well as three task-specific networks that tap into interference resolution, lexical retrieval, and articulation. Forty-two Polish–English bilinguals participated in the study. Our results show that the L2 after-effect reflects increased engagement of domain-general but not language-specific resources. Furthermore, contrary to previously proposed interpretations, we did not find evidence that the effect reflects increased difficulty related to lexical access, articulation, and the resolution of lexical interference. We propose that difficulty of speech production in the picture naming paradigm—manifested as the L2 after-effect—reflects interference at a nonlinguistic level of task schemas or a general increase of cognitive control engagement during speech production in L1 after L2.

    Additional information

    supplementary materials
  • Wolters, G., & Poletiek, F. H. (2008). Beslissen over aangiftes van seksueel misbruik bij kinderen. De Psycholoog, 43, 29-29.
  • Wright, S. E., Windhouwer, M., Schuurman, I., & Kemps-Snijders, M. (2013). Community efforts around the ISOcat Data Category Registry. In I. Gurevych, & J. Kim (Eds.), The People's Web meets NLP: Collaboratively constructed language resources (pp. 349-374). New York: Springer.

    Abstract

    The ISOcat Data Category Registry provides a community computing environment for creating, storing, retrieving, harmonizing and standardizing data category specifications (DCs), used to register linguistic terms used in various fields. This chapter recounts the history of DC documentation in TC 37, beginning from paper-based lists created for lexicographers and terminologists and progressing to the development of a web-based resource for a much broader range of users. While describing the considerable strides that have been made to collect a very large comprehensive collection of DCs, it also outlines difficulties that have arisen in developing a fully operative web-based computing environment for achieving consensus on data category names, definitions, and selections and describes efforts to overcome some of the present shortcomings and to establish positive working procedures designed to engage a wide range of people involved in the creation of language resources.
  • Wright, S. E., & Windhouwer, M. (2013). ISOcat - im Reich der Datenkategorien. eDITion: Fachzeitschrift für Terminologie, 9(1), 8-12.

    Abstract

    Im ISOcat-Datenkategorie-Register (Data Category Registry, www.isocat.org) des Technischen Komitees ISO/TC 37 (Terminology and other language and content resources) werden Feldnamen und Werte für Sprachressourcen beschrieben. Empfohlene Feldnamen und zuverlässige Definitionen sollen dazu beitragen, dass Sprachdaten unabhängig von Anwendungen, Plattformen und Communities of Practice (CoP) wiederverwendet werden können. Datenkategorie-Gruppen (Data Category Selections) können eingesehen, ausgedruckt, exportiert und nach kostenloser Registrierung auch neu erstellt werden.
  • Li, X., Yang, Y., & Hagoort, P. (2008). Pitch accent and lexical tone processing in Chinese discourse comprehension: An ERP study. Brain Research, 1222, 192-200. doi:10.1016/j.brainres.2008.05.031.

    Abstract

    In the present study, event-related brain potentials (ERP) were recorded to investigate the role of pitch accent and lexical tone in spoken discourse comprehension. Chinese was used as material to explore the potential difference in the nature and time course of brain responses to sentence meaning as indicated by pitch accent and to lexical meaning as indicated by tone. In both cases, the pitch contour of critical words was varied. The results showed that both inconsistent pitch accent and inconsistent lexical tone yielded N400 effects, and there was no interaction between them. The negativity evoked by inconsistent pitch accent had the some topography as that evoked by inconsistent lexical tone violation, with a maximum over central–parietal electrodes. Furthermore, the effect for the combined violations was the sum of effects for pure pitch accent and pure lexical tone violation. However, the effect for the lexical tone violation appeared approximately 90 ms earlier than the effect of the pitch accent violation. It is suggested that there might be a correspondence between the neural mechanism underlying pitch accent and lexical meaning processing in context. They both reflect the integration of the current information into a discourse context, independent of whether the current information was sentence meaning indicated by accentuation, or lexical meaning indicated by tone. In addition, lexical meaning was processed earlier than sentence meaning conveyed by pitch accent during spoken language processing.
  • Zeshan, U., Escobedo Delgado, C. E., Dikyuva, H., Panda, S., & De Vos, C. (2013). Cardinal numerals in rural sign languages: Approaching cross-modal typology. Linguistic Typology, 17(3), 357-396. doi:10.1515/lity-2013-0019.

    Abstract

    This article presents data on cardinal numerals in three sign languages from small-scale communities with hereditary deafness. The unusual features found in these data considerably extend the known range of typological variety across sign languages. Some features, such as non-decimal numeral bases, are unattested in sign languages, but familiar from spoken languages, while others, such as subtractive sub-systems, are rare in sign and speech. We conclude that for a complete typological appraisal of a domain, an approach to cross-modal typology, which includes a typologically diverse range of sign languages in addition to spoken languages, is both instructive and feasible.
  • Zeshan, U. (2003). Aspects of Türk Işaret Dili (Turkish Sign Language). Sign Language and Linguistics, 6(1), 43-75. doi:10.1075/sll.6.1.04zes.

    Abstract

    This article provides a first overview of some striking grammatical structures in Türk Idotscedilaret Dili (Turkish Sign Language, TID), the sign language used by the Deaf community in Turkey. The data are described with a typological perspective in mind, focusing on aspects of TID grammar that are typologically unusual across sign languages. After giving an overview of the historical, sociolinguistic and educational background of TID and the language community using this sign language, five domains of TID grammar are investigated in detail. These include a movement derivation signalling completive aspect, three types of nonmanual negation — headshake, backward head tilt, and puffed cheeks — and their distribution, cliticization of the negator NOT to a preceding predicate host sign, an honorific whole-entity classifier used to refer to humans, and a question particle, its history and current status in the language. A final evaluation points out the significance of these data for sign language research and looks at perspectives for a deeper understanding of the language and its history.
  • Zettersten, M., Cox, C., Bergmann, C., Tsui, A. S. M., Soderstrom, M., Mayor, J., Lundwall, R. A., Lewis, M., Kosie, J. E., Kartushina, N., Fusaroli, R., Frank, M. C., Byers-Heinlein, K., Black, A. K., & Mathur, M. B. (2024). Evidence for infant-directed speech preference is consistent across large-scale, multi-site replication and meta-analysis. Open Mind, 8, 439-461. doi:10.1162/opmi_a_00134.

    Abstract

    There is substantial evidence that infants prefer infant-directed speech (IDS) to adult-directed speech (ADS). The strongest evidence for this claim has come from two large-scale investigations: i) a community-augmented meta-analysis of published behavioral studies and ii) a large-scale multi-lab replication study. In this paper, we aim to improve our understanding of the IDS preference and its boundary conditions by combining and comparing these two data sources across key population and design characteristics of the underlying studies. Our analyses reveal that both the meta-analysis and multi-lab replication show moderate effect sizes (d ≈ 0.35 for each estimate) and that both of these effects persist when relevant study-level moderators are added to the models (i.e., experimental methods, infant ages, and native languages). However, while the overall effect size estimates were similar, the two sources diverged in the effects of key moderators: both infant age and experimental method predicted IDS preference in the multi-lab replication study, but showed no effect in the meta-analysis. These results demonstrate that the IDS preference generalizes across a variety of experimental conditions and sampling characteristics, while simultaneously identifying key differences in the empirical picture offered by each source individually and pinpointing areas where substantial uncertainty remains about the influence of theoretically central moderators on IDS preference. Overall, our results show how meta-analyses and multi-lab replications can be used in tandem to understand the robustness and generalizability of developmental phenomena.

    Additional information

    supplementary data link to preprint
  • Zhou, H., Van der Ham, S., De Boer, B., Bogaerts, L., & Raviv, L. (2024). Modality and stimulus effects on distributional statistical learning: Sound vs. sight, time vs. space. Journal of Memory and Language, 138: 104531. doi:10.1016/j.jml.2024.104531.

    Abstract

    Statistical learning (SL) is postulated to play an important role in the process of language acquisition as well as in other cognitive functions. It was found to enable learning of various types of statistical patterns across different sensory modalities. However, few studies have distinguished distributional SL (DSL) from sequential and spatial SL, or examined DSL across modalities using comparable tasks. Considering the relevance of such findings to the nature of SL, the current study investigated the modality- and stimulus-specificity of DSL. Using a within-subject design we compared DSL performance in auditory and visual modalities. For each sensory modality, two stimulus types were used: linguistic versus non-linguistic auditory stimuli and temporal versus spatial visual stimuli. In each condition, participants were exposed to stimuli that varied in their length as they were drawn from two categories (short versus long). DSL was assessed using a categorization task and a production task. Results showed that learners’ performance was only correlated for tasks in the same sensory modality. Moreover, participants were better at categorizing the temporal signals in the auditory conditions than in the visual condition, where in turn an advantage of the spatial condition was observed. In the production task participants exaggerated signal length more for linguistic signals than non-linguistic signals. Together, these findings suggest that DSL is modality- and stimulus-sensitive.

    Additional information

    link to preprint
  • Zioga, I., Zhou, Y. J., Weissbart, H., Martin, A. E., & Haegens, S. (2024). Alpha and beta oscillations differentially support word production in a rule-switching task. eNeuro, 11(4): ENEURO.0312-23.2024. doi:10.1523/ENEURO.0312-23.2024.

    Abstract

    Research into the role of brain oscillations in basic perceptual and cognitive functions has suggested that the alpha rhythm reflects functional inhibition while the beta rhythm reflects neural ensemble (re)activation. However, little is known regarding the generalization of these proposed fundamental operations to linguistic processes, such as speech comprehension and production. Here, we recorded magnetoencephalography in participants performing a novel rule-switching paradigm. Specifically, Dutch native speakers had to produce an alternative exemplar from the same category or a feature of a given target word embedded in spoken sentences (e.g., for the word “tuna”, an exemplar from the same category—“seafood”—would be “shrimp”, and a feature would be “pink”). A cue indicated the task rule—exemplar or feature—either before (pre-cue) or after (retro-cue) listening to the sentence. Alpha power during the working memory delay was lower for retro-cue compared with that for pre-cue in the left hemispheric language-related regions. Critically, alpha power negatively correlated with reaction times, suggestive of alpha facilitating task performance by regulating inhibition in regions linked to lexical retrieval. Furthermore, we observed a different spatiotemporal pattern of beta activity for exemplars versus features in the right temporoparietal regions, in line with the proposed role of beta in recruiting neural networks for the encoding of distinct categories. Overall, our study provides evidence for the generalizability of the role of alpha and beta oscillations from perceptual to more “complex, linguistic processes” and offers a novel task to investigate links between rule-switching, working memory, and word production.
  • Zwitserlood, I. (2008). Grammatica-vertaalmethode en nederlandse gebarentaal. Levende Talen Magazine, 95(5), 28-29.
  • Zwitserlood, I. (2008). Morphology below the level of the sign - frozen forms and classifier predicates. In J. Quer (Ed.), Proceedings of the 8th Conference on Theoretical Issues in Sign Language Research (TISLR) (pp. 251-272). Hamburg: Signum Verlag.

    Abstract

    The lexicons of many sign languages hold large proportions of “frozen” forms, viz. signs that are generally considered to have been formed productively (as classifier predicates), but that have diachronically undergone processes of lexicalisation. Nederlandse Gebarentaal (Sign Language of the Netherlands; henceforth: NGT) also has many of these signs (Van der Kooij 2002, Zwitserlood 2003). In contrast to the general view on “frozen” forms, a few researchers claim that these signs may be formed according to productive sign formation rules, notably Brennan (1990) for BSL, and Meir (2001, 2002) for ISL. Following these claims, I suggest an analysis of “frozen” NGT signs as morphologically complex, using the framework of Distributed Morphology. The signs in question are derived in a similar way as classifier predicates; hence their similar form (but diverging characteristics). I will indicate how and why the structure and use of classifier predicates and “frozen” forms differ. Although my analysis focuses on NGT, it may also be applicable to other sign languages.
  • Zwitserlood, I., Perniss, P. M., & Ozyurek, A. (2013). Expression of multiple entities in Turkish Sign Language (TİD). In E. Arik (Ed.), Current Directions in Turkish Sign Language Research (pp. 272-302). Newcastle upon Tyne: Cambridge Scholars Publishing.

    Abstract

    This paper reports on an exploration of the ways in which multiple entities are expressed in Turkish Sign Language (TİD). The (descriptive and quantitative) analyses provided are based on a corpus of both spontaneous data and specifically elicited data, in order to provide as comprehensive an account as possible. We have found several devices in TİD for expression of multiple entities, in particular localization, spatial plural predicate inflection, and a specific form used to express multiple entities that are side by side in the same configuration (not reported for any other sign language to date), as well as numerals and quantifiers. In contrast to some other signed languages, TİD does not appear to have a productive system of plural reduplication. We argue that none of the devices encountered in the TİD data is a genuine plural marking device and that the plural interpretation of multiple entity localizations and plural predicate inflections is a by-product of the use of space to indicate the existence or the involvement in an event of multiple entities.
  • Zwitserlood, I. (2003). Word formation below and above little x: Evidence from Sign Language of the Netherlands. In Proceedings of SCL 19. Nordlyd Tromsø University Working Papers on Language and Linguistics (pp. 488-502).

    Abstract

    Although in many respects sign languages have a similar structure to that of spoken languages, the different modalities in which both types of languages are expressed cause differences in structure as well. One of the most striking differences between spoken and sign languages is the influence of the interface between grammar and PF on the surface form of utterances. Spoken language words and phrases are in general characterized by sequential strings of sounds, morphemes and words, while in sign languages we find that many phonemes, morphemes, and even words are expressed simultaneously. A linguistic model should be able to account for the structures that occur in both spoken and sign languages. In this paper, I will discuss the morphological/ morphosyntactic structure of signs in Nederlandse Gebarentaal (Sign Language of the Netherlands, henceforth NGT), with special focus on the components ‘place of articulation’ and ‘handshape’. I will focus on their multiple functions in the grammar of NGT and argue that the framework of Distributed Morphology (DM), which accounts for word formation in spoken languages, is also suited to account for the formation of structures in sign languages. First I will introduce the phonological and morphological structure of NGT signs. Then, I will briefly outline the major characteristics of the DM framework. Finally, I will account for signs that have the same surface form but have a different morphological structure by means of that framework.

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