Displaying 1 - 11 of 11
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Amelink, J., Postema, M., Kong, X., Schijven, D., Carrion Castillo, A., Soheili-Nezhad, S., Sha, Z., Molz, B., Joliot, M., Fisher, S. E., & Francks, C. (in press). Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness. Communications Biology, 2023.11.22.568256.
Abstract
Language is supported by a distributed network of brain regions with a particular contribution from the left hemisphere. A multi-level understanding of this network requires studying the genetic architecture of its functional connectivity and hemispheric asymmetry. We used resting state functional imaging data from 29,681 participants from the UK Biobank to measure functional connectivity between 18 left-hemisphere regions implicated in multimodal sentence-level processing, as well as their homotopic regions in the right-hemisphere, and interhemispheric connections. Multivariate genome-wide association analysis of this total network, based on common genetic variants (with population frequencies above 1%), identified 14 loci associated with network functional connectivity. Three of these loci were also associated with hemispheric differences of intrahemispheric connectivity. Polygenic dispositions to lower language-related abilities, dyslexia and left-handedness were associated with generally reduced leftward asymmetry of functional connectivity, but with some trait- and connection-specific exceptions. Exome-wide association analysis based on rare, protein-altering variants (frequencies < 1%) suggested 7 additional genes. These findings shed new light on the genetic contributions to language network connectivity and its asymmetry based on both common and rare genetic variants, and reveal genetic links to language-related traits and hemispheric dominance for hand preference.Additional information
link to preprint -
Defina, R. (in press). Tense, aspect, and mood in Avatime. Afrika und Übersee.
Abstract
The Ghana-Togo Mountain languages are a typologically distinct group of languages within the Kwa branch of the Niger-Congo language family. Until recently, they have received very little documentary attention, and are still greatly under-described. Where there is information regarding the tense, aspect, and mood system, Ghana-Togo Mountain languages are described as tense and aspect prominent. In contrast, Kwa languages are typically aspect and mood prominent, with little to no grammatical tense marking. Is the apparent greater emphasis on tense one of the typological features that separates the Ghana- Togo Mountain languages from the other Kwa languages? Or has tense been overrepresented due to the lack of description? In the case of Avatime, it is the latter. Previous accounts have described Avatime with a strong focus on tense. However, when the semantics are considered in more detail, we see that none of the forms contains an inherent specification for tense. While there is often a default interpretation in the past, present or future, this default can easily be overridden. Thus, Avatime has a typical Kwa system with a focus on aspect and mood and no grammatical tense. -
Den Hoed, J., Hashimoto, H., Khan, M., Semmekrot, F., Bosanko, K., Abe-Hatano, C., Nakagawa, E., Venselaar, H., Quercia, N., Chad, L., Kurosaka, H., Rondeau, S., Fisher, S. E., Yamamoto, S., & Zarate, Y. A. (in press). Pathogenic SATB2 missense variants affecting p.Gly392 have variable functional implications and result in diverse clinical phenotypes. Journal of Medical Genetics.
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García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias Vasquez, A., Athanasiu, L., Bastin, M. E., Beiser, A. S., Bennett, D. A., Bis, J. C. García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias Vasquez, A., Athanasiu, L., Bastin, M. E., Beiser, A. S., Bennett, D. A., Bis, J. C., Boks, M. P. M., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivières, S., Djurovic, S., Ehrlich, S., Erk, S., Espeseth, T., Fernández, G., Filippi, I., Fisher, S. E., Fleischman, D. A., Fletcher, E., Fornage, M., Forstner, A. J., Francks, C., Franke, B., Ge, T., Goldman, A. L., Grabe, H. J., Green, R. C., Grimm, O., Groenewold, N. A., Gruber, O., Gudnason, V., Håberg, A. K., Haukvik, U. K., Heinz, A., Hibar, D. P., Hilal, S., Himali, J. J., Ho, B.-C., Hoehn, D. F., Hoekstra, P. J., Hofer, E., Hoffmann, W., Holmes, A. J., Homuth, G., Hosten, N., Ikram, M. K., Ipser, J. C., Jack Jr, C. R., Jahanshad, N., Jönsson, E. G., Kahn, R. S., Kanai, R., Klein, M., Knol, M. J., Launer, L. J., Lawrie, S. M., Le Hellard, S., Lee, P. H., Lemaître, H., Li, S., Liewald, D. C. M., Lin, H., Longstreth Jr, W. T. L., Lopez, O. L., Luciano, M., Maillard, P., Marquand, A. F., Martin, N. G., Martinot, J.-L., Mather, K. A., Mattay, V. S., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mirza-Schreiber, N., Milaneschi, Y., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Muñoz Maniega, S., Nauck, M., Nho, K., Niessen, W. J., Nöthen, M. M., Nyquist, P. A., Oosterlaan, J., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Psaty, B. M., Pütz, B., Reppermund, S., Rietschel, M. D., Risacher, S. L., Romanczuk-Seiferth, N., Romero-Garcia, R., Roshchupkin, G. V., Rotter, J. I., Sachdev, P. S., Sämann, P. G., Saremi, A., Sargurupremraj, M., Saykin, A. J., Schmaal, L., Schmidt, H., Schmidt, R., Schofield, P. R., Scholz, M., Schumann, G., Schwarz, E., Shen, L., Shin, J., Sisodiya, S. M., Smith, A. V., Smoller, J. W., Soininen, H. S., Steen, V. M., Stein, D. J., Stein, J. L., Thomopoulos, S. I., Toga, A., Tordesillas-Gutiérrez, D. T., Trollor, J. N., Valdes-Hernandez, M. C., Van 't Ent, D., Van Bokhoven, H., Van der Meer, D., Van der Wee, N. J. A., Vázquez-Bourgon, J., Veltman, D. J., Vernooij, M. W., Villringer, A., Vinke, L. N., Völzke, H., Walter, H., Wardlaw, J. M., Weinberger, D. R., Weiner, M. W., Wen, W., Westlye, L. T., Westman, E., White, T., Witte, A. V., Wolf, C., Yang, J., Zwiers, M. P., Ikram, M. A., Seshadri, S., Thompson, P. M., Satizabal, C. L., Medland, S. E., & Rentería, M. E. (in press). Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for brain variation across ancestries. Nature Genetics.
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Hammarström, H., & Parkvall, M. (in press). Basic Constituent Order in Pidgin and Creole Languages: Inheritance or Universals? Journal of Language Contact.
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Kejriwal, J., Mishra, C., Offrede, T., Skantze, G., & Beňuš, Š. (in press). Does a robot’s gaze behavior affect entrainment in HRI? Computing and Informatics.
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Mazzini, S., Seijdel, N., & Drijvers, L. (in press). Short report: Autistic individuals benefit from gestures during degraded speech comprehension. Autism: International Journal of Research and Practice.
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O’Meara, C., Kung, S. S., & Majid, A. (in press). The challenge of olfactory ideophones: Reconsidering ineffability from the Totonac-Tepehua perspective. International Journal of American Linguistics.
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Soderstrom, M., Rocha-Hidalgo, J., Munoz, L. E., Bochynska, A., Werker, J. F., Skarabela, B., Seidl, A., Searle, A., Ryjova, Y., Rennels, J. L., Potter, C., Paulus, M., Ota, M., Noble, C., Nave, K., Mayor, J., Machon, L., Lew-Williams, C., Ko, E.-S., Kartushina, H. K. Soderstrom, M., Rocha-Hidalgo, J., Munoz, L. E., Bochynska, A., Werker, J. F., Skarabela, B., Seidl, A., Searle, A., Ryjova, Y., Rennels, J. L., Potter, C., Paulus, M., Ota, M., Noble, C., Nave, K., Mayor, J., Machon, L., Lew-Williams, C., Ko, E.-S., Kartushina, H. K., Kammermeier, M., Jessop, A., Hay, J. F., Hannon, E. E., Hamlin, J. K., Havron, N., Gonzalez-Gomez, N., Gonzalez-Barrero, A. M., Gampe, A., Fritzsche, T., Frank, M. C., Floccia, C., Durrant, S., Luche, C. D., Davies, C., Cashon, C., Byers-Heinlein, K., Black, A. K., Bergmann, C., Anderson, L., AlShakhori, M. K., Al-Hoorie, A. H., & Tsui, A. S. M. (in press). Testing the relationship between preferences for infant-directed speech and vocabulary development: A multi-lab study. Journal of Child Language.
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Ter Bekke, M., Drijvers, L., & Holler, J. (in press). Co-speech hand gestures are used to predict upcoming meaning. Psychological Science.
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Tsomokos, D., & Raviv, L. (in press). A bidirectional association between language development and prosocial behaviour in childhood: Evidence from a longitudinal birth cohort in the UK. Developmental Psychology.
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