Publications

Displaying 301 - 400 of 473
  • Mitterer, H., & Ernestus, M. (2008). The link between speech perception and production is phonological and abstract: Evidence from the shadowing task. Cognition, 109(1), 168-173. doi:10.1016/j.cognition.2008.08.002.

    Abstract

    This study reports a shadowing experiment, in which one has to repeat a speech stimulus as fast as possible. We tested claims about a direct link between perception and production based on speech gestures, and obtained two types of counterevidence. First, shadowing is not slowed down by a gestural mismatch between stimulus and response. Second, phonetic detail is more likely to be imitated in a shadowing task if it is phonologically relevant. This is consistent with the idea that speech perception and speech production are only loosely coupled, on an abstract phonological level.
  • Mitterer, H., Yoneyama, K., & Ernestus, M. (2008). How we hear what is hardly there: Mechanisms underlying compensation for /t/-reduction in speech comprehension. Journal of Memory and Language, 59, 133-152. doi:10.1016/j.jml.2008.02.004.

    Abstract

    In four experiments, we investigated how listeners compensate for reduced /t/ in Dutch. Mitterer and Ernestus [Mitterer,H., & Ernestus, M. (2006). Listeners recover /t/s that speakers lenite: evidence from /t/-lenition in Dutch. Journal of Phonetics, 34, 73–103] showed that listeners are biased to perceive a /t/ more easily after /s/ than after /n/, compensating for the tendency of speakers to reduce word-final /t/ after /s/ in spontaneous conversations. We tested the robustness of this phonological context effect in perception with three very different experimental tasks: an identification task, a discrimination task with native listeners and with non-native listeners who do not have any experience with /t/-reduction,and a passive listening task (using electrophysiological dependent measures). The context effect was generally robust against these experimental manipulations, although we also observed some deviations from the overall pattern. Our combined results show that the context effect in compensation for reduced /t/ results from a complex process involving auditory constraints, phonological learning, and lexical constraints.
  • Mitterer, H., & McQueen, J. M. (2009). Foreign subtitles help but native-language subtitles harm foreign speech perception. PLoS ONE, 4(11), e7785. doi:10.1371/journal.pone.0007785.

    Abstract

    Understanding foreign speech is difficult, in part because of unusual mappings between sounds and words. It is known that listeners in their native language can use lexical knowledge (about how words ought to sound) to learn how to interpret unusual speech-sounds. We therefore investigated whether subtitles, which provide lexical information, support perceptual learning about foreign speech. Dutch participants, unfamiliar with Scottish and Australian regional accents of English, watched Scottish or Australian English videos with Dutch, English or no subtitles, and then repeated audio fragments of both accents. Repetition of novel fragments was worse after Dutch-subtitle exposure but better after English-subtitle exposure. Native-language subtitles appear to create lexical interference, but foreign-language subtitles assist speech learning by indicating which words (and hence sounds) are being spoken.
  • Mitterer, H., & McQueen, J. M. (2009). Processing reduced word-forms in speech perception using probabilistic knowledge about speech production. Journal of Experimental Psychology: Human Perception and Performance, 35(1), 244-263. doi:10.1037/a0012730.

    Abstract

    Two experiments examined how Dutch listeners deal with the effects of connected-speech processes, specifically those arising from word-final /t/ reduction (e.g., whether Dutch [tas] is tas, bag, or a reduced-/t/ version of tast, touch). Eye movements of Dutch participants were tracked as they looked at arrays containing 4 printed words, each associated with a geometrical shape. Minimal pairs (e.g., tas/tast) were either both above (boven) or both next to (naast) different shapes. Spoken instructions (e.g., “Klik op het woordje tas boven de ster,” [Click on the word bag above the star]) thus became unambiguous only on their final words. Prior to disambiguation, listeners' fixations were drawn to /t/-final words more when boven than when naast followed the ambiguous sequences. This behavior reflects Dutch speech-production data: /t/ is reduced more before /b/ than before /n/. We thus argue that probabilistic knowledge about the effect of following context in speech production is used prelexically in perception to help resolve lexical ambiguities caused by continuous-speech processes.
  • Mitterer, H., Horschig, J. M., Müsseler, J., & Majid, A. (2009). The influence of memory on perception: It's not what things look like, it's what you call them. Journal of Experimental Psychology: Learning, Memory, and Cognition, 35(6), 1557-1562. doi:10.1037/a0017019.

    Abstract

    World knowledge influences how we perceive the world. This study shows that this influence is at least partly mediated by declarative memory. Dutch and German participants categorized hues from a yellow-to-orange continuum on stimuli that were prototypically orange or yellow and that were also associated with these color labels. Both groups gave more “yellow” responses if an ambiguous hue occurred on a prototypically yellow stimulus. The language groups were also tested on a stimulus (traffic light) that is associated with the label orange in Dutch and with the label yellow in German, even though the objective color is the same for both populations. Dutch observers categorized this stimulus as orange more often than German observers, in line with the assumption that declarative knowledge mediates the influence of world knowledge on color categorization.

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  • Morgan, J. L., Van Elswijk, G., & Meyer, A. S. (2008). Extrafoveal processing of objects in a naming task: Evidence from word probe experiments. Psychonomic Bulletin & Review, 15, 561-565. doi:10.3758/PBR.15.3.561.

    Abstract

    In two experiments, we investigated the processing of extrafoveal objects in a double-object naming task. On most trials, participants named two objects; but on some trials, the objects were replaced shortly after trial onset by a written word probe, which participants had to name instead of the objects. In Experiment 1, the word was presented in the same location as the left object either 150 or 350 msec after trial onset and was either phonologically related or unrelated to that object name. Phonological facilitation was observed at the later but not at the earlier SOA. In Experiment 2, the word was either phonologically related or unrelated to the right object and was presented 150 msec after the speaker had begun to inspect that object. In contrast with Experiment 1, phonological facilitation was found at this early SOA, demonstrating that the speakers had begun to process the right object prior to fixation.
  • Mortensen, L., Meyer, A. S., & Humphreys, G. W. (2008). Speech planning during multiple-object naming: Effects of ageing. Quarterly Journal of Experimental Psychology, 61, 1217 -1238. doi:10.1080/17470210701467912.

    Abstract

    Two experiments were conducted with younger and older speakers. In Experiment 1, participants named single objects that were intact or visually degraded, while hearing distractor words that were phonologically related or unrelated to the object name. In both younger and older participants naming latencies were shorter for intact than for degraded objects and shorter when related than when unrelated distractors were presented. In Experiment 2, the single objects were replaced by object triplets, with the distractors being phonologically related to the first object's name. Naming latencies and gaze durations for the first object showed degradation and relatedness effects that were similar to those in single-object naming. Older participants were slower than younger participants when naming single objects and slower and less fluent on the second but not the first object when naming object triplets. The results of these experiments indicate that both younger and older speakers plan object names sequentially, but that older speakers use this planning strategy less efficiently.
  • Narasimhan, B., & Dimroth, C. (2008). Word order and information status in child language. Cognition, 107, 317-329. doi:10.1016/j.cognition.2007.07.010.

    Abstract

    In expressing rich, multi-dimensional thought in language, speakers are influenced by a range of factors that influence the ordering of utterance constituents. A fundamental principle that guides constituent ordering in adults has to do with information status, the accessibility of referents in discourse. Typically, adults order previously mentioned referents (“old” or accessible information) first, before they introduce referents that have not yet been mentioned in the discourse (“new” or inaccessible information) at both sentential and phrasal levels. Here we ask whether a similar principle influences ordering patterns at the phrasal level in children who are in the early stages of combining words productively. Prior research shows that when conveying semantic relations, children reproduce language-specific ordering patterns in the input, suggesting that they do not have a bias for any particular order to describe “who did what to whom”. But our findings show that when they label “old” versus “new” referents, 3- to 5-year-old children prefer an ordering pattern opposite to that of adults (Study 1). Children’s ordering preference is not derived from input patterns, as “old-before-new” is also the preferred order in caregivers’ speech directed to young children (Study 2). Our findings demonstrate that a key principle governing ordering preferences in adults does not originate in early childhood, but develops: from new-to-old to old-to-new.
  • Need, A. C., Ge, D., Weale, M. E., Maia, J., Feng, S., Heinzen, E. L., Shianna, K. V., Yoon, W., Kasperavičiūtė, D., Gennarelli, M., Strittmatter, W. J., Bonvicini, C., Rossi, G., Jayathilake, K., Cola, P. A., McEvoy, J. P., Keefe, R. S. E., Fisher, E. M. C., St. Jean, P. L., Giegling, I. and 13 moreNeed, A. C., Ge, D., Weale, M. E., Maia, J., Feng, S., Heinzen, E. L., Shianna, K. V., Yoon, W., Kasperavičiūtė, D., Gennarelli, M., Strittmatter, W. J., Bonvicini, C., Rossi, G., Jayathilake, K., Cola, P. A., McEvoy, J. P., Keefe, R. S. E., Fisher, E. M. C., St. Jean, P. L., Giegling, I., Hartmann, A. M., Möller, H.-J., Ruppert, A., Fraser, G., Crombie, C., Middleton, L. T., St. Clair, D., Roses, A. D., Muglia, P., Francks, C., Rujescu, D., Meltzer, H. Y., & Goldstein, D. B. (2009). A genome-wide investigation of SNPs and CNVs in schizophrenia. PLoS Genetics, 5(2), e1000373. doi:10.1371/journal.pgen.1000373.

    Abstract

    We report a genome-wide assessment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) in schizophrenia. We investigated SNPs using 871 patients and 863 controls, following up the top hits in four independent cohorts comprising 1,460 patients and 12,995 controls, all of European origin. We found no genome-wide significant associations, nor could we provide support for any previously reported candidate gene or genome-wide associations. We went on to examine CNVs using a subset of 1,013 cases and 1,084 controls of European ancestry, and a further set of 60 cases and 64 controls of African ancestry. We found that eight cases and zero controls carried deletions greater than 2 Mb, of which two, at 8p22 and 16p13.11-p12.4, are newly reported here. A further evaluation of 1,378 controls identified no deletions greater than 2 Mb, suggesting a high prior probability of disease involvement when such deletions are observed in cases. We also provide further evidence for some smaller, previously reported, schizophrenia-associated CNVs, such as those in NRXN1 and APBA2. We could not provide strong support for the hypothesis that schizophrenia patients have a significantly greater “load” of large (>100 kb), rare CNVs, nor could we find common CNVs that associate with schizophrenia. Finally, we did not provide support for the suggestion that schizophrenia-associated CNVs may preferentially disrupt genes in neurodevelopmental pathways. Collectively, these analyses provide the first integrated study of SNPs and CNVs in schizophrenia and support the emerging view that rare deleterious variants may be more important in schizophrenia predisposition than common polymorphisms. While our analyses do not suggest that implicated CNVs impinge on particular key pathways, we do support the contribution of specific genomic regions in schizophrenia, presumably due to recurrent mutation. On balance, these data suggest that very few schizophrenia patients share identical genomic causation, potentially complicating efforts to personalize treatment regimens.
  • Need, A. C., Attix, D. K., McEvoy, J. M., Cirulli, E. T., Linney, K. N., Wagoner, A. P., Gumbs, C. E., Giegling, I., Möller, H.-J., Francks, C., Muglia, P., Roses, A., Gibson, G., Weale, M. E., Rujescu, D., & Goldstein, D. B. (2008). Failure to replicate effect of Kibra on human memory in two large cohorts of European origin. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B, 667-668. doi:10.1002/ajmg.b.30658.

    Abstract

    It was recently suggested that the Kibra polymorphism rs17070145 has a strong effect on multiple episodic memory tasks in humans. We attempted to replicate this using two cohorts of European genetic origin (n = 319 and n = 365). We found no association with either the original SNP or a set of tagging SNPs in the Kibra gene with multiple verbal memory tasks, including one that was an exact replication (Auditory Verbal Learning Task, AVLT). These results suggest that Kibra does not have a strong and general effect on human memory.

    Additional information

    SupplementaryMethodsIAmJMedGen.doc
  • Newbury, D. F., Winchester, L., Addis, L., Paracchini, S., Buckingham, L.-L., Clark, A., Cohen, W., Cowie, H., Dworzynski, K., Everitt, A., Goodyer, I. M., Hennessy, E., Kindley, A. D., Miller, L. L., Nasir, J., O'Hare, A., Shaw, D., Simkin, Z., Simonoff, E., Slonims, V. and 11 moreNewbury, D. F., Winchester, L., Addis, L., Paracchini, S., Buckingham, L.-L., Clark, A., Cohen, W., Cowie, H., Dworzynski, K., Everitt, A., Goodyer, I. M., Hennessy, E., Kindley, A. D., Miller, L. L., Nasir, J., O'Hare, A., Shaw, D., Simkin, Z., Simonoff, E., Slonims, V., Watson, J., Ragoussis, J., Fisher, S. E., Seckl, J. R., Helms, P. J., Bolton, P. F., Pickles, A., Conti-Ramsden, G., Baird, G., Bishop, D. V., & Monaco, A. P. (2009). CMIP and ATP2C2 modulate phonological short-term memory in language impairment. American Journal of Human Genetics, 85(2), 264-272. doi:10.1016/j.ajhg.2009.07.004.

    Abstract

    Specific language impairment (SLI) is a common developmental disorder haracterized by difficulties in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors. We performed a high-density screen of SLI1, a region of chromosome 16q that shows highly significant and consistent linkage to nonword repetition, a measure of phonological short-term memory that is commonly impaired in SLI. Using two independent language-impaired samples, one family-based (211 families) and another selected from a population cohort on the basis of extreme language measures (490 cases), we detected association to two genes in the SLI1 region: that encoding c-maf-inducing protein (CMIP, minP = 5.5 × 10−7 at rs6564903) and that encoding calcium-transporting ATPase, type2C, member2 (ATP2C2, minP = 2.0 × 10−5 at rs11860694). Regression modeling indicated that each of these loci exerts an independent effect upon nonword repetition ability. Despite the consistent findings in language-impaired samples, investigation in a large unselected cohort (n = 3612) did not detect association. We therefore propose that variants in CMIP and ATP2C2 act to modulate phonological short-term memory primarily in the context of language impairment. As such, this investigation supports the hypothesis that some causes of language impairment are distinct from factors that influence normal language variation. This work therefore implicates CMIP and ATP2C2 in the etiology of SLI and provides molecular evidence for the importance of phonological short-term memory in language acquisition.

    Additional information

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  • Newman-Norlund, S. E., Noordzij, M. L., Newman-Norlund, R. D., Volman, I. A., De Ruiter, J. P., Hagoort, P., & Toni, I. (2009). Recipient design in tacit communication. Cognition, 111, 46-54. doi:10.1016/j.cognition.2008.12.004.

    Abstract

    The ability to design tailored messages for specific listeners is an important aspect of
    human communication. The present study investigates whether a mere belief about an
    addressee’s identity influences the generation and production of a communicative message in
    a novel, non-verbal communication task. Participants were made to believe they were playing a game with a child or an adult partner, while a confederate acted as both child
    and adult partners with matched performance and response times. The participants’ belief
    influenced their behavior, spending longer when interacting with the presumed child
    addressee, but only during communicative portions of the game, i.e. using time as a tool
    to place emphasis on target information. This communicative adaptation attenuated with
    experience, and it was related to personality traits, namely Empathy and Need for Cognition
    measures. Overall, these findings indicate that novel nonverbal communicative interactions
    are selected according to a socio-centric perspective, and they are strongly
    influenced by participants’ traits.
  • Niemi, J., Laine, M., & Järvikivi, J. (2009). Paradigmatic and extraparadigmatic morphology in the mental lexicon: Experimental evidence for a dissociation. The mental lexicon, 4(1), 26-40. doi:10.1075/ml.4.1.02nie.

    Abstract

    The present study discusses psycholinguistic evidence for a difference between paradigmatic and extraparadigmatic morphology by investigating the processing of Finnish inflected and cliticized words. The data are derived from three sources of Finnish: from single-word reading performance in an agrammatic deep dyslectic speaker, as well as from visual lexical decision and wordness/learnability ratings of cliticized vs. inflected items by normal Finnish speakers. The agrammatic speaker showed awareness of the suffixes in multimorphemic words, including clitics, since he attempted to fill in this slot with morphological material. However, he never produced a clitic — either as the correct response or as an error — in any morphological configuration (simplex, derived, inflected, compound). Moreover, he produced more nominative singular errors for case-inflected nouns than he did for the cliticized words, a pattern that is expected if case-inflected forms were closely associated with their lexical heads, i.e., if they were paradigmatic and cliticized words were not. Furthermore, a visual lexical decision task with normal speakers of Finnish, showed an additional processing cost (longer latencies and more errors on cliticized than on case-inflected noun forms). Finally, a rating task indicated no difference in relative wordness between these two types of words. However, the same cliticized words were judged harder to learn as L2 items than the inflected words, most probably due to their conceptual/semantic properties, in other words due to their lack of word-level translation equivalents in SAVE languages. Taken together, the present results suggest that the distinction between paradigmatic and extraparadigmatic morphology is psychologically real.
  • Nieuwland, M. S., & Van Berkum, J. J. A. (2008). The neurocognition of referential ambiguity in language comprehension. Language and Linguistics Compass, 2(4), 603-630. doi:10.1111/j.1749-818x.2008.00070.x.

    Abstract

    Referential ambiguity arises whenever readers or listeners are unable to select a unique referent for a linguistic expression out of multiple candidates. In the current article, we review a series of neurocognitive experiments from our laboratory that examine the neural correlates of referential ambiguity, and that employ the brain signature of referential ambiguity to derive functional properties of the language comprehension system. The results of our experiments converge to show that referential ambiguity resolution involves making an inference to evaluate the referential candidates. These inferences only take place when both referential candidates are, at least initially, equally plausible antecedents. Whether comprehenders make these anaphoric inferences is strongly context dependent and co-determined by characteristics of the reader. In addition, readers appear to disregard referential ambiguity when the competing candidates are each semantically incoherent, suggesting that, under certain circumstances, semantic analysis can proceed even when referential analysis has not yielded a unique antecedent. Finally, results from a functional neuroimaging study suggest that whereas the neural systems that deal with referential ambiguity partially overlap with those that deal with referential failure, they show an inverse coupling with the neural systems associated with semantic processing, possibly reflecting the relative contributions of semantic and episodic processing to re-establish semantic and referential coherence, respectively.
  • Nieuwland, M. S., & Van Berkum, J. J. A. (2008). The interplay between semantic and referential aspects of anaphoric noun phrase resolution: Evidence from ERPs. Brain & Language, 106, 119-131. doi:10.1016/j.bandl.2008.05.001.

    Abstract

    In this event-related brain potential (ERP) study, we examined how semantic and referential aspects of anaphoric noun phrase resolution interact during discourse comprehension. We used a full factorial design that crossed referential ambiguity with semantic incoherence. Ambiguous anaphors elicited a sustained negative shift (Nref effect), and incoherent anaphors elicited an N400 effect. Simultaneously ambiguous and incoherent anaphors elicited an ERP pattern resembling that of the incoherent anaphors. These results suggest that semantic incoherence can preclude readers from engaging in anaphoric inferencing. Furthermore, approximately half of our participants unexpectedly showed common late positive effects to the three types of problematic anaphors. We relate the latter finding to recent accounts of what the P600 might reflect, and to the role of individual differences therein.
  • Nieuwland, M. S., & Kuperberg, G. R. (2008). When the truth Is not too hard to handle. An event-related potential study on the pragmatics of negation. Psychological Science, 19(12), 1213-1218. doi:10.1111/j.1467-9280.2008.02226.x.

    Abstract

    Our brains rapidly map incoming language onto what we hold to be true. Yet there are claims that such integration and verification processes are delayed in sentences containing negation words like not. However, studies have often confounded whether a statement is true and whether it is a natural thing to say during normal communication. In an event-related potential (ERP) experiment, we aimed to disentangle effects of truth value and pragmatic licensing on the comprehension of affirmative and negated real-world statements. As in affirmative sentences, false words elicited a larger N400 ERP than did true words in pragmatically licensed negated sentences (e.g., “In moderation, drinking red wine isn't bad/good…”), whereas true and false words elicited similar responses in unlicensed negated sentences (e.g., “A baby bunny's fur isn't very hard/soft…”). These results suggest that negation poses no principled obstacle for readers to immediately relate incoming words to what they hold to be true.
  • Nijland, L., & Janse, E. (Eds.). (2009). Auditory processing in speakers with acquired or developmental language disorders [Special Issue]. Clinical Linguistics and Phonetics, 23(3).
  • Nobe, S., Furuyama, N., Someya, Y., Sekine, K., Suzuki, M., & Hayashi, K. (2008). A longitudinal study on gesture of simultaneous interpreter. The Japanese Journal of Speech Sciences, 8, 63-83.
  • Noordzij, M., Newman-Norlund, S. E., De Ruiter, J. P., Hagoort, P., Levinson, S. C., & Toni, I. (2009). Brain mechanisms underlying human communication. Frontiers in Human Neuroscience, 3:14. doi:10.3389/neuro.09.014.2009.

    Abstract

    Human communication has been described as involving the coding-decoding of a conventional symbol system, which could be supported by parts of the human motor system (i.e. the “mirror neurons system”). However, this view does not explain how these conventions could develop in the first place. Here we target the neglected but crucial issue of how people organize their non-verbal behavior to communicate a given intention without pre-established conventions. We have measured behavioral and brain responses in pairs of subjects during communicative exchanges occurring in a real, interactive, on-line social context. In two fMRI studies, we found robust evidence that planning new communicative actions (by a sender) and recognizing the communicative intention of the same actions (by a receiver) relied on spatially overlapping portions of their brains (the right posterior superior temporal sulcus). The response of this region was lateralized to the right hemisphere, modulated by the ambiguity in meaning of the communicative acts, but not by their sensorimotor complexity. These results indicate that the sender of a communicative signal uses his own intention recognition system to make a prediction of the intention recognition performed by the receiver. This finding supports the notion that our communicative abilities are distinct from both sensorimotor processes and language abilities.
  • Norris, D., & McQueen, J. M. (2008). Shortlist B: A Bayesian model of continuous speech recognition. Psychological Review, 115(2), 357-395. doi:10.1037/0033-295X.115.2.357.

    Abstract

    A Bayesian model of continuous speech recognition is presented. It is based on Shortlist ( D. Norris, 1994; D. Norris, J. M. McQueen, A. Cutler, & S. Butterfield, 1997) and shares many of its key assumptions: parallel competitive evaluation of multiple lexical hypotheses, phonologically abstract prelexical and lexical representations, a feedforward architecture with no online feedback, and a lexical segmentation algorithm based on the viability of chunks of the input as possible words. Shortlist B is radically different from its predecessor in two respects. First, whereas Shortlist was a connectionist model based on interactive-activation principles, Shortlist B is based on Bayesian principles. Second, the input to Shortlist B is no longer a sequence of discrete phonemes; it is a sequence of multiple phoneme probabilities over 3 time slices per segment, derived from the performance of listeners in a large-scale gating study. Simulations are presented showing that the model can account for key findings: data on the segmentation of continuous speech, word frequency effects, the effects of mispronunciations on word recognition, and evidence on lexical involvement in phonemic decision making. The success of Shortlist B suggests that listeners make optimal Bayesian decisions during spoken-word recognition.
  • Obleser, J., Eisner, F., & Kotz, S. A. (2008). Bilateral speech comprehension reflects differential sensitivity to spectral and temporal features. Journal of Neuroscience, 28(32), 8116-8124. doi:doi:10.1523/JNEUROSCI.1290-08.2008.

    Abstract

    Speech comprehension has been shown to be a strikingly bilateral process, but the differential contributions of the subfields of left and right auditory cortices have remained elusive. The hypothesis that left auditory areas engage predominantly in decoding fast temporal perturbations of a signal whereas the right areas are relatively more driven by changes of the frequency spectrum has not been directly tested in speech or music. This brain-imaging study independently manipulated the speech signal itself along the spectral and the temporal domain using noise-band vocoding. In a parametric design with five temporal and five spectral degradation levels in word comprehension, a functional distinction of the left and right auditory association cortices emerged: increases in the temporal detail of the signal were most effective in driving brain activation of the left anterolateral superior temporal sulcus (STS), whereas the right homolog areas exhibited stronger sensitivity to the variations in spectral detail. In accordance with behavioral measures of speech comprehension acquired in parallel, change of spectral detail exhibited a stronger coupling with the STS BOLD signal. The relative pattern of lateralization (quantified using lateralization quotients) proved reliable in a jack-knifed iterative reanalysis of the group functional magnetic resonance imaging model. This study supplies direct evidence to the often implied functional distinction of the two cerebral hemispheres in speech processing. Applying direct manipulations to the speech signal rather than to low-level surrogates, the results lend plausibility to the notion of complementary roles for the left and right superior temporal sulci in comprehending the speech signal.
  • Obleser, J., & Eisner, F. (2009). Pre-lexical abstraction of speech in the auditory cortex. Trends in Cognitive Sciences, 13, 14-19. doi:10.1016/j.tics.2008.09.005.

    Abstract

    Speech perception requires the decoding of complex acoustic patterns. According to most cognitive models of spoken word recognition, this complexity is dealt with before lexical access via a process of abstraction from the acoustic signal to pre-lexical categories. It is currently unclear how these categories are implemented in the auditory cortex. Recent advances in animal neurophysiology and human functional imaging have made it possible to investigate the processing of speech in terms of probabilistic cortical maps rather than simple cognitive subtraction, which will enable us to relate neurometric data more directly to behavioural studies. We suggest that integration of insights from cognitive science, neurophysiology and functional imaging is necessary for furthering our understanding of pre-lexical abstraction in the cortex.

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  • Ogasawara, N., & Warner, N. (2009). Processing missing vowels: Allophonic processing in Japanese. Language and Cognitive Processes, 24, 376 -411. doi:10.1080/01690960802084028.

    Abstract

    The acoustic realisation of a speech sound varies, often showing allophonic variation triggered by surrounding sounds. Listeners recognise words and sounds well despite such variation, and even make use of allophonic variability in processing. This study reports five experiments on processing of the reduced/unreduced allophonic alternation of Japanese high vowels. The results show that listeners use phonological knowledge of their native language during phoneme processing and word recognition. However, interactions of the phonological and acoustic effects differ in these two processes. A facilitatory phonological effect and an inhibitory acoustic effect cancel one another out in phoneme processing; while in word recognition, the facilitatory phonological effect overrides the inhibitory acoustic effect. Four potential models of the processing of allophonic variation are discussed. The results can be accommodated in two of them, but require additional assumptions or modifications to the models, and primarily support lexical specification of allophonic variability.

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  • Orfanidou, E., Adam, R., McQueen, J. M., & Morgan, G. (2009). Making sense of nonsense in British Sign Language (BSL): The contribution of different phonological parameters to sign recognition. Memory & Cognition, 37(3), 302-315. doi:10.3758/MC.37.3.302.

    Abstract

    Do all components of a sign contribute equally to its recognition? In the present study, misperceptions in the sign-spotting task (based on the word-spotting task; Cutler & Norris, 1988) were analyzed to address this question. Three groups of deaf signers of British Sign Language (BSL) with different ages of acquisition (AoA) saw BSL signs combined with nonsense signs, along with combinations of two nonsense signs. They were asked to spot real signs and report what they had spotted. We will present an analysis of false alarms to the nonsense-sign combinations—that is, misperceptions of nonsense signs as real signs (cf. van Ooijen, 1996). Participants modified the movement and handshape parameters more than the location parameter. Within this pattern, however, there were differences as a function of AoA. These results show that the theoretical distinctions between form-based parameters in sign-language models have consequences for online processing. Vowels and consonants have different roles in speech recognition; similarly, it appears that movement, handshape, and location parameters contribute differentially to sign recognition.
  • Otten, M., & Van Berkum, J. J. A. (2009). Does working memory capacity affect the ability to predict upcoming words in discourse? Brain Research, 1291, 92-101. doi:doi:10.1016/j.brainres.2009.07.042.

    Abstract

    Prior research has indicated that readers and listeners can use information in the prior discourse to rapidly predict specific upcoming words, as the text is unfolding. Here we used event-related potentials to explore whether the ability to make rapid online predictions depends on a reader's working memory capacity (WMC). Readers with low WMC were hypothesized to differ from high WMC readers either in their overall capability to make predictions (because of their lack of cognitive resources). High and low WMC participants read highly constraining stories that supported the prediction of a specific noun, mixed with coherent but essentially unpredictive ‘prime control’ control stories that contained the same content words as the predictive stories. To test whether readers were anticipating upcoming words, critical nouns were preceded by a determiner whose gender agreed or disagreed with the gender of the expected noun. In predictive stories, both high and low WMC readers displayed an early negative deflection (300–600 ms) to unexpected determiners, which was not present in prime control stories. Only the low WMC participants displayed an additional later negativity (900–1500 ms) to unexpected determiners. This pattern of results suggests that WMC does not influence the ability to anticipate upcoming words per se, but does change the way in which readers deal with information that disconfirms the generated prediction.
  • Otten, M., & Van Berkum, J. J. A. (2008). Discourse-based word anticipation during language processing: Prediction of priming? Discourse Processes, 45, 464-496. doi:10.1080/01638530802356463.

    Abstract

    Language is an intrinsically open-ended system. This fact has led to the widely shared assumption that readers and listeners do not predict upcoming words, at least not in a way that goes beyond simple priming between words. Recent evidence, however, suggests that readers and listeners do anticipate upcoming words “on the fly” as a text unfolds. In 2 event-related potentials experiments, this study examined whether these predictions are based on the exact message conveyed by the prior discourse or on simpler word-based priming mechanisms. Participants read texts that strongly supported the prediction of a specific word, mixed with non-predictive control texts that contained the same prime words. In Experiment 1A, anomalous words that replaced a highly predictable (as opposed to a non-predictable but coherent) word elicited a long-lasting positive shift, suggesting that the prior discourse had indeed led people to predict specific words. In Experiment 1B, adjectives whose suffix mismatched the predictable noun's syntactic gender elicited a short-lived late negativity in predictive stories but not in prime control stories. Taken together, these findings reveal that the conceptual basis for predicting specific upcoming words during reading is the exact message conveyed by the discourse and not the mere presence of prime words.
  • Ozyurek, A., Kita, S., Allen, S., Brown, A., Furman, R., & Ishizuka, T. (2008). Development of cross-linguistic variation in speech and gesture: motion events in English and Turkish. Developmental Psychology, 44(4), 1040-1054. doi:10.1037/0012-1649.44.4.1040.

    Abstract

    The way adults express manner and path components of a motion event varies across typologically different languages both in speech and cospeech gestures, showing that language specificity in event encoding influences gesture. The authors tracked when and how this multimodal cross-linguistic variation develops in children learning Turkish and English, 2 typologically distinct languages. They found that children learn to speak in language-specific ways from age 3 onward (i.e., English speakers used 1 clause and Turkish speakers used 2 clauses to express manner and path). In contrast, English- and Turkish-speaking children’s gestures looked similar at ages 3 and 5 (i.e., separate gestures for manner and path), differing from each other only at age 9 and in adulthood (i.e., English speakers used 1 gesture, but Turkish speakers used separate gestures for manner and path). The authors argue that this pattern of the development of cospeech gestures reflects a gradual shift to language-specific representations during speaking and shows that looking at speech alone may not be sufficient to understand the full process of language acquisition.
  • Patel, A. D., Iversen, J. R., Wassenaar, M., & Hagoort, P. (2008). Musical syntactic processing in agrammatic Broca's aphasia. Aphasiology, 22(7/8), 776-789. doi:10.1080/02687030701803804.

    Abstract

    Background: Growing evidence for overlap in the syntactic processing of language and music in non-brain-damaged individuals leads to the question of whether aphasic individuals with grammatical comprehension problems in language also have problems processing structural relations in music.

    Aims: The current study sought to test musical syntactic processing in individuals with Broca's aphasia and grammatical comprehension deficits, using both explicit and implicit tasks.

    Methods & Procedures: Two experiments were conducted. In the first experiment 12 individuals with Broca's aphasia (and 14 matched controls) were tested for their sensitivity to grammatical and semantic relations in sentences, and for their sensitivity to musical syntactic (harmonic) relations in chord sequences. An explicit task (acceptability judgement of novel sequences) was used. The second experiment, with 9 individuals with Broca's aphasia (and 12 matched controls), probed musical syntactic processing using an implicit task (harmonic priming).

    Outcomes & Results: In both experiments the aphasic group showed impaired processing of musical syntactic relations. Control experiments indicated that this could not be attributed to low-level problems with the perception of pitch patterns or with auditory short-term memory for tones.

    Conclusions: The results suggest that musical syntactic processing in agrammatic aphasia deserves systematic investigation, and that such studies could help probe the nature of the processing deficits underlying linguistic agrammatism. Methodological suggestions are offered for future work in this little-explored area.
  • Pijnacker, J., Geurts, B., Van Lambalgen, M., Kan, C. C., Buitelaar, J. K., & Hagoort, P. (2009). Defeasible reasoning in high-functioning adults with autism: Evidence for impaired exception-handling. Neuropsychologia, 47, 644-651. doi:10.1016/j.neuropsychologia.2008.11.011.

    Abstract

    While autism is one of the most intensively researched psychiatric disorders, little is known about reasoning skills of people with autism. The focus of this study was on defeasible inferences, that is inferences that can be revised in the light of new information. We used a behavioral task to investigate (a) conditional reasoning and (b) the suppression of conditional inferences in high-functioning adults with autism. In the suppression task a possible exception was made salient which could prevent a conclusion from being drawn. We predicted that the autism group would have difficulties dealing with such exceptions because they require mental flexibility to adjust to the context, which is often impaired in autism. The findings confirm our hypothesis that high-functioning adults with autism have a specific difficulty with exception-handling during reasoning. It is suggested that defeasible reasoning is also involved in other cognitive domains. Implications for neural underpinnings of reasoning and autism are discussed.
  • Pijnacker, J., Hagoort, P., Buitelaar, J., Teunisse, J.-P., & Geurts, B. (2009). Pragmatic inferences in high-functioning adults with autism and Asperger syndrome. Journal of Autism and Developmental Disorders, 39(4), 607-618. doi:10.1007/s10803-008-0661-8.

    Abstract

    Although people with autism spectrum disorders (ASD) often have severe problems with pragmatic aspects of language, little is known about their pragmatic reasoning. We carried out a behavioral study on highfunctioning adults with autistic disorder (n = 11) and Asperger syndrome (n = 17) and matched controls (n = 28) to investigate whether they are capable of deriving scalar implicatures, which are generally considered to be pragmatic inferences. Participants were presented with underinformative sentences like ‘‘Some sparrows are birds’’. This sentence is logically true, but pragmatically inappropriate if the scalar implicature ‘‘Not all sparrows are birds’’ is derived. The present findings indicate that the combined ASD group was just as likely as controls to derive scalar implicatures, yet there was a difference between participants with autistic disorder and Asperger syndrome, suggesting a potential differentiation between these disorders in pragmatic reasoning. Moreover, our results suggest that verbal intelligence is a constraint for task performance in autistic disorder but not in Asperger syndrome.
  • Poletiek, F. H. (2008). Het probleem van escalerende beschuldigingen [Boekbespreking van Kindermishandeling door H. Crombag en den Hartog]. Maandblad voor Geestelijke Volksgezondheid, (2), 163-166.
  • Poletiek, F. H., & Van Schijndel, T. J. P. (2009). Stimulus set size and statistical coverage of the grammar in artificial grammar learning. Psychonomic Bulletin & Review, 16(6), 1058-1064. doi:10.3758/PBR.16.6.1058.

    Abstract

    Adults and children acquire knowledge of the structure of their environment on the basis of repeated exposure to samples of structured stimuli. In the study of inductive learning, a straightforward issue is how much sample information is needed to learn the structure. The present study distinguishes between two measures for the amount of information in the sample: set size and the extent to which the set of exemplars statistically covers the underlying structure. In an artificial grammar learning experiment, learning was affected by the sample’s statistical coverage of the grammar, but not by its mere size. Our result suggests an alternative explanation of the set size effects on learning found in previous studies (McAndrews & Moscovitch, 1985; Meulemans & Van der Linden, 1997), because, as we argue, set size was confounded with statistical coverage in these studies. nt]mis|This research was supported by a grant from the Netherlands Organization for Scientific Research. We thank Jarry Porsius for his help with the data analyses.
  • Poletiek, F. H. (2009). Popper's Severity of Test as an intuitive probabilistic model of hypothesis testing. Behavioral and Brain Sciences, 32(1), 99-100. doi:10.1017/S0140525X09000454.
  • Poletiek, F. H., & Wolters, G. (2009). What is learned about fragments in artificial grammar learning? A transitional probabilities approach. Quarterly Journal of Experimental Psychology, 62(5), 868-876. doi:10.1080/17470210802511188.

    Abstract

    Learning local regularities in sequentially structured materials is typically assumed to be based on encoding of the frequencies of these regularities. We explore the view that transitional probabilities between elements of chunks, rather than frequencies of chunks, may be the primary factor in artificial grammar learning (AGL). The transitional probability model (TPM) that we propose is argued to provide an adaptive and parsimonious strategy for encoding local regularities in order to induce sequential structure from an input set of exemplars of the grammar. In a variant of the AGL procedure, in which participants estimated the frequencies of bigrams occurring in a set of exemplars they had been exposed to previously, participants were shown to be more sensitive to local transitional probability information than to mere pattern frequencies.
  • Powlesland, A. S., Hitchen, P. G., Parry, S., Graham, S. A., Barrio, M. M., Elola, M. T., Mordoh, J., Dell, A., Drickamer, K., & Taylor, M. E. (2009). Targeted glycoproteomic identification of cancer cell glycosylation. Glycobiology, 9, 899-909. doi:10.1093/glycob/cwp065.

    Abstract

    GalMBP is a fragment of serum mannose-binding protein that has been modified to create a probe for galactose-containing ligands. Glycan array screening demonstrated that the carbohydrate-recognition domain of GalMBP selectively binds common groups of tumor-associated glycans, including Lewis-type structures and T antigen, suggesting that engineered glycan-binding proteins such as GalMBP represent novel tools for the characterization of glycoproteins bearing tumor-associated glycans. Blotting of cell extracts and membranes from MCF7 breast cancer cells with radiolabeled GalMBP was used to demonstrate that it binds to a selected set of high molecular weight glycoproteins that could be purified from MCF7 cells on an affinity column constructed with GalMBP. Proteomic and glycomic analysis of these glycoproteins by mass spectrometry showed that they are forms of CD98hc that bear glycans displaying heavily fucosylated termini, including Lewis(x) and Lewis(y) structures. The pool of ligands was found to include the target ligands for anti-CD15 antibodies, which are commonly used to detect Lewis(x) antigen on tumors, and for the endothelial scavenger receptor C-type lectin, which may be involved in tumor metastasis through interactions with this antigen. A survey of additional breast cancer cell lines reveals that there is wide variation in the types of glycosylation that lead to binding of GalMBP. Higher levels of binding are associated either with the presence of outer-arm fucosylated structures carried on a variety of different cell surface glycoproteins or with the presence of high levels of the mucin MUC1 bearing T antigen.

    Additional information

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  • Praamstra, P., Meyer, A. S., & Levelt, W. J. M. (1994). Neurophysiological manifestations of auditory phonological processing: Latency variation of a negative ERP component timelocked to phonological mismatch. Journal of Cognitive Neuroscience, 6(3), 204-219. doi:10.1162/jocn.1994.6.3.204.

    Abstract

    Two experiments examined phonological priming effects on reaction times, error rates, and event-related brain potential (ERP) measures in an auditory lexical decision task. In Experiment 1 related prime-target pairs rhymed, and in Experiment 2 they alliterated (i.e., shared the consonantal onset and vowel). Event-related potentials were recorded in a delayed response task. Reaction times and error rates were obtained both for the delayed and an immediate response task. The behavioral data of Experiment 1 provided evidence for phonological facilitation of word, but not of nonword decisions. The brain potentials were more negative to unrelated than to rhyming word-word pairs between 450 and 700 msec after target onset. This negative enhancement was not present for word-nonword pairs. Thus, the ERP results match the behavioral data. The behavioral data of Experiment 2 provided no evidence for phonological Facilitation. However, between 250 and 450 msec after target onset, i.e., considerably earlier than in Experiment 1, brain potentials were more negative for unrelated than for alliterating word and word-nonword pairs. It is argued that the ERP effects in the two experiments could be modulations of the same underlying component, possibly the N400. The difference in the timing of the effects is likely to be due to the fact that the shared segments in related stimulus pairs appeared in different word positions in the two experiments.
  • Praamstra, P., Hagoort, P., Maassen, B., & Crul, T. (1991). Word deafness and auditory cortical function: A case history and hypothesis. Brain, 114, 1197-1225. doi:10.1093/brain/114.3.1197.

    Abstract

    A patient who already had Wernick's aphasia due to a left temporal lobe lesion suffered a severe deterioration specifically of auditory language comprehension, subsequent to right temporal lobe infarction. A detailed comparison of his new condition with his language status before the second stroke revealed that the newly acquired deficit was limited to tasks related to auditory input. Further investigations demonstrated a speech perceptual disorder, which we analysed as due to deficits both at the level of general auditory processes and at the level of phonetic analysis. We discuss some arguments related to hemisphere specialization of phonetic processing and to the disconnection explanation of word deafness that support the hypothesis of word deafness being generally caused by mixed deficits.
  • Proios, H., Asaridou, S. S., & Brugger, P. (2008). Random number generation in patients with aphasia: A test of executive functions. Acta Neuropsychologica, 6(2), 157-168.

    Abstract

    Randomization performance was studied using the "Mental Dice Task" in 20 patients with aphasia (APH) and 101 elderly normal control subjects (NC). The produced sequences were compared to 100 computer-generated pseudorandom sequences with respect to 7 measures of sequential bias. The performance of APH differed significantly from NC participants, according to all but one measure, i.e. Turning Point Index (points of change between ascending and descending sequences). NC participants differed significantly from the computer generated sequences, according to all measures of randomness. Finally, APH differed significantly from the computer simulator, according to all measures but mean Repetition Gap score (gap between a digit and its reoccurrence). Despite the heterogeneity of our APH group, there were no significant differences in randomization performance between patients with different language impairments. All the APH displayed a distinct performance profile, with more response stereotypy, counting tendencies, and inhibition problems, as hypothesised, while at the same time responding more randomly than NC by showing less of a cycling strategy and more number repetitions.
  • Protopapas, A., & Gerakaki, S. (2009). Development of processing stress diacritics in reading Greek. Scientific Studies of Reading, 13(6), 453-483. doi:10.1080/10888430903034788.

    Abstract

    In Greek orthography, stress position is marked with a diacritic. We investigated the developmental course of processing the stress diacritic in Grades 2 to 4. Ninety children read 108 pseudowords presented without or with a diacritic either in the same or in a different position relative to the source word. Half of the pseudowords resembled the words they were derived from. Results showed that lexical sources of stress assignment were active in Grade 2 and remained stronger than the diacritic through Grade 4. The effect of the diacritic increased more rapidly and approached the lexical effect with increasing grade. In a second experiment, 90 children read 54 words and 54 pseudowords. The pattern of results for words was similar to that for nonwords suggesting that findings regarding stress assignment using nonwords may generalize to word reading. Decoding of the diacritic does not appear to be the preferred option for developing readers.
  • Pylkkänen, L., Martin, A. E., McElree, B., & Smart, A. (2009). The Anterior Midline Field: Coercion or decision making? Brain and Language, 108(3), 184-190. doi:10.1016/j.bandl.2008.06.006.

    Abstract

    To study the neural bases of semantic composition in language processing without confounds from syntactic composition, recent magnetoencephalography (MEG) studies have investigated the processing of constructions that exhibit some type of syntax-semantics mismatch. The most studied case of such a mismatch is complement coercion; expressions such as the author began the book, where an entity-denoting noun phrase is coerced into an eventive meaning in order to match the semantic properties of the event-selecting verb (e.g., ‘the author began reading/writing the book’). These expressions have been found to elicit increased activity in the Anterior Midline Field (AMF), an MEG component elicited at frontomedial sensors at ∼400 ms after the onset of the coercing noun [Pylkkänen, L., & McElree, B. (2007). An MEG study of silent meaning. Journal of Cognitive Neuroscience, 19, 11]. Thus, the AMF constitutes a potential neural correlate of coercion. However, the AMF was generated in ventromedial prefrontal regions, which are heavily associated with decision-making. This raises the possibility that, instead of semantic processing, the AMF effect may have been related to the experimental task, which was a sensicality judgment. We tested this hypothesis by assessing the effect of coercion when subjects were simply reading for comprehension, without a decision-task. Additionally, we investigated coercion in an adjectival rather than a verbal environment to further generalize the findings. Our results show that an AMF effect of coercion is elicited without a decision-task and that the effect also extends to this novel syntactic environment. We conclude that in addition to its role in non-linguistic higher cognition, ventromedial prefrontal regions contribute to the resolution of syntax-semantics mismatches in language processing.
  • Qin, S., Rijpkema, M., Tendolkar, I., Piekema, C., Hermans, E. J., Binder, M., Petersson, K. M., Luo, J., & Fernández, G. (2009). Dissecting medial temporal lobe contributions to item and associative memory formation. NeuroImage, 46, 874-881. doi:10.1016/j.neuroimage.2009.02.039.

    Abstract

    A fundamental and intensively discussed question is whether medial temporal lobe (MTL) processes that lead to non-associative item memories differ in their anatomical substrate from processes underlying associative memory formation. Using event-related functional magnetic resonance imaging, we implemented a novel design to dissociate brain activity related to item and associative memory formation not only by subsequent memory performance and anatomy but also in time, because the two constituents of each pair to be memorized were presented sequentially with an intra-pair delay of several seconds. Furthermore, the design enabled us to reduce potential differences in memory strength between item and associative memory by increasing task difficulty in the item recognition memory test. Confidence ratings for correct item recognition for both constituents did not differ between trials in which only item memory was correct and trials in which item and associative memory were correct. Specific subsequent memory analyses for item and associative memory formation revealed brain activity that appears selectively related to item memory formation in the posterior inferior temporal, posterior parahippocampal, and perirhinal cortices. In contrast, hippocampal and inferior prefrontal activity predicted successful retrieval of newly formed inter-item associations. Our findings therefore suggest that different MTL subregions indeed play distinct roles in the formation of item memory and inter-item associative memory as expected by several dual process models of the MTL memory system.
  • Rapold, C. J., & Widlok, T. (2008). Dimensions of variability in Northern Khoekhoe language and culture. Southern African Humanities, 20, 133-161. Retrieved from http://www.sahumanities.org.za/RapoldWidlok_203.aspx.

    Abstract

    This article takes an interdisciplinary route towards explaining the complex history of Hai//om culture and language. We begin this article with a short review of ideas relating to 'origins' and historical reconstructions as they are currently played out among Khoekhoe groups in Namibia, in particular with regard to the Hai//om. We then take a comparative look at parts of the kinship system and the tonology of ≠Âkhoe Hai//om and other variants of Khoekhoe. With regard to the kinship and naming system, we see patterns that show similarities with Nama and Damara on the one hand but also with 'San' groups on the other hand. With regard to tonology, new data from three northern Khoekoe varieties shows similarities as well as differences with Standard Namibian Khoekhoe and Ju and Tuu varieties. The historical scenarios that might explain these facts suggest different centres of innovations and opposite directions of diffusion. The anthropological and linguistic data demonstrates that only a fine-grained and multi-layered approach that goes far beyond any simplistic dichotomies can do justice to the Hai//om riddle.
  • Reesink, G., Singer, R., & Dunn, M. (2009). Explaining the linguistic diversity of Sahul using population models. PLoS Biology, 7(11), e1000241. doi:10.1371/journal.pbio.1000241.

    Abstract

    The region of the ancient Sahul continent (present day Australia and New Guinea, and surrounding islands) is home to extreme linguistic diversity. Even apart from the huge Austronesian language family, which spread into the area after the breakup of the Sahul continent in the Holocene, there are hundreds of languages from many apparently unrelated families. On each of the subcontinents, the generally accepted classification recognizes one large, widespread family and a number of unrelatable smaller families. If these language families are related to each other, it is at a depth which is inaccessible to standard linguistic methods. We have inferred the history of structural characteristics of these languages under an admixture model, using a Bayesian algorithm originally developed to discover populations on the basis of recombining genetic markers. This analysis identifies 10 ancestral language populations, some of which can be identified with clearly defined phylogenetic groups. The results also show traces of early dispersals, including hints at ancient connections between Australian languages and some Papuan groups (long hypothesized, never before demonstrated). Systematic language contact effects between members of big phylogenetic groups are also detected, which can in some cases be identified with a diffusional or substrate signal. Most interestingly, however, there remains striking evidence of a phylogenetic signal, with many languages showing negligible amounts of admixture.
  • Richards, J. B., Waterworth, D., O'Rahilly, S., Hivert, M.-F., Loos, R. J. F., Perry, J. R. B., Tanaka, T., Timpson, N. J., Semple, R. K., Soranzo, N., Song, K., Rocha, N., Grundberg, E., Dupuis, J., Florez, J. C., Langenberg, C., Prokopenko, I., Saxena, R., Sladek, R., Aulchenko, Y. and 47 moreRichards, J. B., Waterworth, D., O'Rahilly, S., Hivert, M.-F., Loos, R. J. F., Perry, J. R. B., Tanaka, T., Timpson, N. J., Semple, R. K., Soranzo, N., Song, K., Rocha, N., Grundberg, E., Dupuis, J., Florez, J. C., Langenberg, C., Prokopenko, I., Saxena, R., Sladek, R., Aulchenko, Y., Evans, D., Waeber, G., Erdmann, J., Burnett, M.-S., Sattar, N., Devaney, J., Willenborg, C., Hingorani, A., Witteman, J. C. M., Vollenweider, P., Glaser, B., Hengstenberg, C., Ferrucci, L., Melzer, D., Stark, K., Deanfield, J., Winogradow, J., Grassl, M., Hall, A. S., Egan, J. M., Thompson, J. R., Ricketts, S. L., König, I. R., Reinhard, W., Grundy, S., Wichmann, H.-E., Barter, P., Mahley, R., Kesaniemi, Y. A., Rader, D. J., Reilly, M. P., Epstein, S. E., Stewart, A. F. R., Van Duijn, C. M., Schunkert, H., Burling, K., Deloukas, P., Pastinen, T., Samani, N. J., McPherson, R., Davey Smith, G., Frayling, T. M., Wareham, N. J., Meigs, J. B., Mooser, V., Spector, T. D., & Consortium, G. (2009). A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genetics, 5(12): e1000768. doi:10.1371/journal.pgen.1000768.

    Abstract

    The adipocyte-derived protein adiponectin is highly heritable and inversely associated with risk of type 2 diabetes mellitus (T2D) and coronary heart disease (CHD). We meta-analyzed 3 genome-wide association studies for circulating adiponectin levels (n = 8,531) and sought validation of the lead single nucleotide polymorphisms (SNPs) in 5 additional cohorts (n = 6,202). Five SNPs were genome-wide significant in their relationship with adiponectin (P<} or =5x10(-8)). We then tested whether these 5 SNPs were associated with risk of T2D and CHD using a Bonferroni-corrected threshold of P{< or =0.011 to declare statistical significance for these disease associations. SNPs at the adiponectin-encoding ADIPOQ locus demonstrated the strongest associations with adiponectin levels (P-combined = 9.2x10(-19) for lead SNP, rs266717, n = 14,733). A novel variant in the ARL15 (ADP-ribosylation factor-like 15) gene was associated with lower circulating levels of adiponectin (rs4311394-G, P-combined = 2.9x10(-8), n = 14,733). This same risk allele at ARL15 was also associated with a higher risk of CHD (odds ratio [OR] = 1.12, P = 8.5x10(-6), n = 22,421) more nominally, an increased risk of T2D (OR = 1.11, P = 3.2x10(-3), n = 10,128), and several metabolic traits. Expression studies in humans indicated that ARL15 is well-expressed in skeletal muscle. These findings identify a novel protein, ARL15, which influences circulating adiponectin levels and may impact upon CHD risk.
  • Roberts, L., Gullberg, M., & Indefrey, P. (2008). Online pronoun resolution in L2 discourse: L1 influence and general learner effects. Studies in Second Language Acquisition, 30(3), 333-357. doi:10.1017/S0272263108080480.

    Abstract

    This study investigates whether advanced second language (L2) learners of a nonnull subject language (Dutch) are influenced by their null subject first language (L1) (Turkish) in their offline and online resolution of subject pronouns in L2 discourse. To tease apart potential L1 effects from possible general L2 processing effects, we also tested a group of German L2 learners of Dutch who were predicted to perform like the native Dutch speakers. The two L2 groups differed in their offline interpretations of subject pronouns. The Turkish L2 learners exhibited a L1 influence, because approximately half the time they interpreted Dutch subject pronouns as they would overt pronouns in Turkish, whereas the German L2 learners performed like the Dutch controls, interpreting pronouns as coreferential with the current discourse topic. This L1 effect was not in evidence in eye-tracking data, however. Instead, the L2 learners patterned together, showing an online processing disadvantage when two potential antecedents for the pronoun were grammatically available in the discourse. This processing disadvantage was in evidence irrespective of the properties of the learners' L1 or their final interpretation of the pronoun. Therefore, the results of this study indicate both an effect of the L1 on the L2 in offline resolution and a general L2 processing effect in online subject pronoun resolution.
  • Roberts, L. (2008). Processing temporal constraints and some implications for the investigation of second language sentence processing and acquisition. Commentary on Baggio. Language Learning, 58(suppl. 1), 57-61. doi:10.1111/j.1467-9922.2008.00461.x.
  • Roby, A. C., & Kidd, E. (2008). The referential communication skills of children with imaginary companions. Developmental Science, 11(4), 531-40. doi:10.1111/j.1467-7687.2008.00699.x.

    Abstract

    he present study investigated the referential communication skills of children with imaginary companions (ICs). Twenty-two children with ICs aged between 4 and 6 years were compared to 22 children without ICs (NICs). The children were matched for age, gender, birth order, number of siblings, and parental education. All children completed the Test of Referential Commu- nication (Camaioni, Ercolani & Lloyd, 1995). The results showed that the children with ICs performed better than the children without ICs on the speaker component of the task. In particular, the IC children were better able to identify a specific referen t to their interlocutor than were the NIC children. Furthermore, the IC children described less redundant features of the target picture than did the NIC children. The children did not differ in the listening comprehension component of the task. Overall, the results suggest that the IC children had a better understanding of their interlocutor’s information requirements in convers ation. The role of pretend play in the development of communicative competence is discussed in light of these results.
  • Rossi, G. (2009). Il discorso scritto interattivo degli SMS: Uno studio pragmatico del "messaggiare". Rivista Italiana di Dialettologia, 33, 143-193. doi:10.1400/148734.
  • De Rover, M., Petersson, K. M., Van der Werf, S. P., Cools, A. R., Berger, H. J., & Fernández, G. (2008). Neural correlates of strategic memory retrieval: Differentiating between spatial-associative and temporal-associative strategies. Human Brain Mapping, 29, 1068-1079. doi:10.1002/hbm.20445.

    Abstract

    Remembering complex, multidimensional information typically requires strategic memory retrieval, during which information is structured, for instance by spatial- or temporal associations. Although brain regions involved in strategic memory retrieval in general have been identified, differences in retrieval operations related to distinct retrieval strategies are not well-understood. Thus, our aim was to identify brain regions whose activity is differentially involved in spatial-associative and temporal-associative retrieval. First, we showed that our behavioral paradigm probing memory for a set of object-location associations promoted the use of a spatial-associative structure following an encoding condition that provided multiple associations to neighboring objects (spatial-associative condition) and the use of a temporal- associative structure following another study condition that provided predominantly temporal associations between sequentially presented items (temporal-associative condition). Next, we used an adapted version of this paradigm for functional MRI, where we contrasted brain activity related to the recall of object-location associations that were either encoded in the spatial- or the temporal-associative condition. In addition to brain regions generally involved in recall, we found that activity in higher-order visual regions, including the fusiform gyrus, the lingual gyrus, and the cuneus, was relatively enhanced when subjects used a spatial-associative structure for retrieval. In contrast, activity in the globus pallidus and the thalamus was relatively enhanced when subjects used a temporal-associative structure for retrieval. In conclusion, we provide evidence for differential involvement of these brain regions related to different types of strategic memory retrieval and the neural structures described play a role in either spatial-associative or temporal-associative memory retrieval.
  • Rowland, C. F., & Theakston, A. L. (2009). The acquisition of auxiliary syntax: A longitudinal elicitation study. Part 2: The modals and auxiliary DO. Journal of Speech, Language, and Hearing Research, 52, 1471-1492. doi:10.1044/1092-4388(2009/08-0037a).

    Abstract

    Purpose: The study of auxiliary acquisition is central to work on language development and has attracted theoretical work from both nativist and constructivist approaches. This study is part of a 2-part companion set that represents a unique attempt to trace the development of auxiliary syntax by using a longitudinal elicitation methodology. The aim of the research described in this part is to track the development of modal auxiliaries and auxiliary DO in questions and declaratives to provide a more complete picture of the development of the auxiliary system in English-speaking children. Method: Twelve English-speaking children participated in 2 tasks designed to elicit auxiliaries CAN, WILL, and DOES in declaratives and yes/no questions. They completed each task 6 times in total between the ages of 2;10 (years;months) and 3;6. Results: The children’s levels of correct use of the target auxiliaries differed in complex ways according to auxiliary, polarity, and sentence structure, and these relations changed over development. An analysis of the children’s errors also revealed complex interactions between these factors. Conclusions: These data cannot be explained in full by existing theories of auxiliary acquisition. Researchers working within both generativist and constructivist frameworks need to develop more detailed theories of acquisition that predict the pattern of acquisition observed.
  • Rubio-Fernández, P. (2008). Concept narrowing: The role of context-independent information. Journal of Biomedical Semantics, 25(4), 381-409. doi:10.1093/jos/ffn004.

    Abstract

    The present study aims to investigate the extent to which the process of lexical interpretation is context dependent. It has been uncontroversially agreed in psycholinguistics that interpretation is always affected by sentential context. The major debate in lexical processing research has revolved around the question of whether initial semantic activation is context sensitive or rather exhaustive, that is, whether the effect of context occurs before or only after the information associated to a concept has been accessed from the mental lexicon. However, within post-lexical access processes, the question of whether the selection of a word's meaning components is guided exclusively by contextual relevance, or whether certain meaning components might be selected context independently, has not been such an important focus of research. I have investigated this question in the two experiments reported in this paper and, moreover, have analysed the role that context-independent information in concepts might play in word interpretation. This analysis differs from previous studies on lexical processing in that it places experimental work in the context of a theoretical model of lexical pragmatics.
  • De Ruiter, J. P., & Levinson, S. C. (2008). A biological infrastructure for communication underlies the cultural evolution of languages [Commentary on Christiansen & Chater: Language as shaped by the brain]. Behavioral and Brain Sciences, 31(5), 518-518. doi:10.1017/S0140525X08005086.

    Abstract

    Universal Grammar (UG) is indeed evolutionarily implausible. But if languages are just “adapted” to a large primate brain, it is hard to see why other primates do not have complex languages. The answer is that humans have evolved a specialized and uniquely human cognitive architecture, whose main function is to compute mappings between arbitrary signals and communicative intentions. This underlies the development of language in the human species.
  • De Ruiter, L. E. (2009). The prosodic marking of topical referents in the German "Vorfeld" by children and adults. The Linguistic Review, 26, 329-354. doi:10.1515/tlir.2009.012.

    Abstract

    This article reports on the analysis of prosodic marking of topical referents in the German prefield by 5- and 7-year-old children and adults. Natural speech data was obtained from a picture-elicited narration task. The data was analyzed both phonologically and phonetically. In line with previous findings, adult speakers realized topical referents predominantly with the accents L+H* and L*+H, but H* accents and unaccented items were also observed. Children used the same accent types as adults, but the accent types were distributed differently. Also, children aligned pitch minima earlier than adults and produced accents with a decreased speed of pitch change. Possible reasons for these findings are discussed. Contrast – defined in terms of a change of subjecthood – did not affect the choice of pitch accent type and did not influence phonetic realization, underlining the fact that accentuation is often a matter of individual speaker choice.

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  • Scheeringa, R., Bastiaansen, M. C. M., Petersson, K. M., Oostenveld, R., Norris, D. G., & Hagoort, P. (2008). Frontal theta EEG activity correlates negatively with the default mode network in resting state. International Journal of Psychophysiology, 67, 242-251. doi:10.1016/j.ijpsycho.2007.05.017.

    Abstract

    We used simultaneously recorded EEG and fMRI to investigate in which areas the BOLD signal correlates with frontal theta power changes, while subjects were quietly lying resting in the scanner with their eyes open. To obtain a reliable estimate of frontal theta power we applied ICA on band-pass filtered (2–9 Hz) EEG data. For each subject we selected the component that best matched the mid-frontal scalp topography associated with the frontal theta rhythm. We applied a time-frequency analysis on this component and used the time course of the frequency bin with the highest overall power to form a regressor that modeled spontaneous fluctuations in frontal theta power. No significant positive BOLD correlations with this regressor were observed. Extensive negative correlations were observed in the areas that together form the default mode network. We conclude that frontal theta activity can be seen as an EEG index of default mode network activity.
  • Scheeringa, R., Petersson, K. M., Oostenveld, R., Norris, D. G., Hagoort, P., & Bastiaansen, M. C. M. (2009). Trial-by-trial coupling between EEG and BOLD identifies networks related to alpha and theta EEG power increases during working memory maintenance. Neuroimage, 44, 1224-1238. doi:10.1016/j.neuroimage.2008.08.041.

    Abstract

    PET and fMRI experiments have previously shown that several brain regions in the frontal and parietal lobe are involved in working memory maintenance. MEG and EEG experiments have shown parametric increases with load for oscillatory activity in posterior alpha and frontal theta power. In the current study we investigated whether the areas found with fMRI can be associated with these alpha and theta effects by measuring simultaneous EEG and fMRI during a modified Sternberg task This allowed us to correlate EEG at the single trial level with the fMRI BOLD signal by forming a regressor based on single trial alpha and theta
    power estimates. We observed a right posterior, parametric alpha power increase, which was functionally related to decreases in BOLD in the primary visual cortex and in the posterior part of the right middle temporal gyrus. We relate this finding to the inhibition of neuronal activity that may interfere with WM maintenance. An observed parametric increase in frontal theta power was correlated to a decrease in BOLD in
    regions that together form the default mode network. We did not observe correlations between oscillatory EEG phenomena and BOLD in the traditional WM areas. In conclusion, the study shows that simultaneous EEG fMRI recordings can be successfully used to identify the emergence of functional networks in the brain during the execution of a cognitive task.
  • Schiller, N., Horemans, I., Ganushchak, L. Y., & Koester, D. (2009). Event-related brain potentials during monitoring of speech errors. NeuroImage, 44, 520-530. doi:10.1016/j.neuroimage.2008.09.019.

    Abstract

    When we perceive speech, our goal is to extract the meaning of the verbal message which includes semantic processing. However, how deeply do we process speech in different situations? In two experiments, native Dutch participants heard spoken sentences describing simultaneously presented pictures. Sentences either correctly described the pictures or contained an anomalous final word (i.e. a semantically or phonologically incongruent word). In the first experiment, spoken sentences were task-irrelevant and both anomalous conditions elicited similar centro-parietal N400s that were larger in amplitude than the N400 for the correct condition. In the second experiment, we ensured that participants processed the same stimuli semantically. In an early time window, we found similar phonological mismatch negativities for both anomalous conditions compared to the correct condition. These negativities were followed by an N400 that was larger for semantic than phonological errors. Together, these data suggest that we process speech semantically, even if the speech is task-irrelevant. Once listeners allocate more cognitive resources to the processing of speech, we suggest that they make predictions for upcoming words, presumably by means of the production system and an internal monitoring loop, to facilitate lexical processing of the perceived speech
  • Schimke, S., Verhagen, J., & Dimroth, C. (2008). Particules additives et finitude en néerlandais et allemand L2: Étude expérimentale. Acquisition et Interaction en Language Etrangère, 26, 191-210.

    Abstract

    Cette étude traite de la question de savoir s’il y a une relation entre les équivalents des particules additives ‘aussi’ et ‘de nouveau’ portant sur le topique et la finitude dans la variété des apprenants turcophones du néerlandais et de l’allemand. Dans les données obtenues avec une tâche contrôlée, nous observons que la finitude est moins fréquemment marquée dans les énoncés contenant ces particules que les énoncés comparables qui ne contiennent pas ces particules. Ceci est vrai pour le marquage de la finitude sur les verbes lexicaux ainsi que pour la présence de verbes conjugués sans contenu lexical comme la copule. De plus, nous montrons que les particules peuvent précéder le verbe conjugué dans la langue des apprenants. Ces résultats peuvent être expliqués par la similarité fonctionnelle entre la finitude et les particules portant sur le topique.
  • Schoffelen, J.-M., Oostenveld, R., & Fries, P. (2008). Imaging the human motor system's beta-band synchronization during isometric contraction. NeuroImage, 41, 437-447. doi:10.1016/j.neuroimage.2008.01.045.

    Abstract

    Rhythmic synchronization likely subserves interactions among neuronal groups. One of the best studied rhythmic synchronization phenomena in the human nervous system is the beta-band (15-30 Hz) synchronization in the motor system. In this study, we imaged structures across the human brain that are synchronized to the motor system's beta rhythm. We recorded whole-head magnetoencephalograms (MEG) and electromyograms (EMG) of left/right extensor carpi radialis muscle during left/right wrist extension. We analyzed coherence, on the one hand between the EMG and neuronal sources in the brain, and on the other hand between different brain sources, using a spatial filtering approach. Cortico-muscular coherence analysis revealed a spatial maximum of coherence to the muscle in motor cortex contralateral to the muscle in accordance with earlier findings. Moreover, by applying a two-dipole source model, we unveiled significantly coherent clusters of voxels in the ipsilateral cerebellar hemisphere and ipsilateral cerebral motor regions. The spatial pattern of coherence to the right and left arm EMG was roughly mirror reversed across the midline, in agreement with known physiology. Subsequently, we analyzed the brain-wide pattern of beta-band coherence to the motor cortex contralateral to the contracting muscle. This analysis did not reveal any convincing pattern. Because the prior cortico-muscular analysis had demonstrated the expected pattern in our data, this negative finding demonstrates a current limitation of the applied method for cortico-cortical coherence analysis. We conclude that during an isometric muscle contraction, several distributed brain regions form a brain-wide beta-band network for motor control.
  • Schoffelen, J.-M., & Gross, J. (2009). Source connectivity analysis with MEG and EEG. Human Brain Mapping, 30, 1857-1865. doi: 10.1002/hbm.20745.

    Abstract

    Interactions between functionally specialized brain regions are crucial for normal brain function. Magnetoencephalography (MEG) and electroencephalography (EEG) are techniques suited to capture these interactions, because they provide whole head measurements of brain activity in the millisecond range. More than one sensor picks up the activity of an underlying source. This field spread severely limits the utility of connectivity measures computed directly between sensor recordings. Consequentially, neuronal interactions should be studied on the level of the reconstructed sources. This article reviews several methods that have been applied to investigate interactions between brain regions in source space. We will mainly focus on the different measures used to quantify connectivity, and on the different strategies adopted to identify regions of interest. Despite various successful accounts of MEG and EEG source connectivity, caution with respect to the interpretation of the results is still warranted. This is due to the fact that effects of field spread can never be completely abolished in source space. However, in this very exciting and developing field of research this cautionary note should not discourage researchers from further investigation into the connectivity between neuronal sources.
  • De Schryver, J., Neijt, A., Ghesquière, P., & Ernestus, M. (2008). Analogy, frequency, and sound change: The case of Dutch devoicing. Journal of Germanic Linguistics, 20(2), 159-195. doi:10.1017/S1470542708000056.

    Abstract

    This study investigates the roles of phonetic analogy and lexical frequency in an ongoing sound change, the devoicing of fricatives in Dutch, which occurs mainly in the Netherlands and to a lesser degree in Flanders. In the experiment, Dutch and Flemish students read two variants of 98 words: the standard and a nonstandard form with the incorrect voice value of the fricative. Dutch students chose the non-standard forms with devoiced fricatives more often than Flemish students. Moreover, devoicing, though a gradual process, appeared lexically diffused, affecting first the words that are low in frequency and phonetically similar to words with voiceless fricatives.
  • Schulte im Walde, S., Melinger, A., Roth, M., & Weber, A. (2008). An empirical characterization of response types in German association norms. Research on Language and Computation, 6, 205-238. doi:10.1007/s11168-008-9048-4.

    Abstract

    This article presents a study to distinguish and quantify the various types of semantic associations provided by humans, to investigate their properties, and to discuss the impact that our analyses may have on NLP tasks. Specifically, we concentrate on two issues related to word properties and word relations: (1) We address the task of modelling word meaning by empirical features in data-intensive lexical semantics. Relying on large-scale corpus-based resources, we identify the contextual categories and functions that are activated by the associates and therefore contribute to the salient meaning components of individual words and across words. As a result, we discuss conceptual roles and present evidence for the usefulness of co-occurrence information in distributional descriptions. (2) We assume that semantic associates provide a means to investigate the range of semantic relations between words and contexts, and we provide insight into which types of semantic relations are treated as important or salient by the speakers of the language.

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  • Schuppler, B., van Doremalen, J., Scharenborg, O., Cranen, B., & Boves, L. (2009). Using temporal information for improving articulatory-acoustic feature classification. Automatic Speech Recognition and Understanding, IEEE 2009 Workshop, 70-75. doi:10.1109/ASRU.2009.5373314.

    Abstract

    This paper combines acoustic features with a high temporal and a high frequency resolution to reliably classify articulatory events of short duration, such as bursts in plosives. SVM classification experiments on TIMIT and SVArticulatory showed that articulatory-acoustic features (AFs) based on a combination of MFCCs derived from a long window of 25ms and a short window of 5ms that are both shifted with 2.5ms steps (Both) outperform standard MFCCs derived with a window of 25 ms and a shift of 10 ms (Baseline). Finally, comparison of the TIMIT and SVArticulatory results showed that for classifiers trained on data that allows for asynchronously changing AFs (SVArticulatory) the improvement from Baseline to Both is larger than for classifiers trained on data where AFs change simultaneously with the phone boundaries (TIMIT).
  • Schwager, W., & Zeshan, U. (2008). Word classes in sign languages: Criteria and classifications. Studies in Language, 32(3), 509-545. doi:10.1075/sl.32.3.03sch.

    Abstract

    The topic of word classes remains curiously under-represented in the sign language literature due to many theoretical and methodological problems in sign linguistics. This article focuses on language-specific classifications of signs into word classes in two different sign languages: German Sign Language and Kata Kolok, the sign language of a village community in Bali. The article discusses semantic and structural criteria for identifying word classes in the target sign languages. On the basis of a data set of signs, these criteria are systematically tested out as a first step towards an inductive classification of signs. Approaches and analyses relating to the problem of word classes in linguistic typology are used for shedding new light on the issue of word class distinctions in sign languages
  • Scott, S. K., McGettigan, C., & Eisner, F. (2009). A little more conversation, a little less action: Candidate roles for motor cortex in speech perception. Nature Reviews Neuroscience, 10(4), 295-302. doi:10.1038/nrn2603.

    Abstract

    The motor theory of speech perception assumes that activation of the motor system is essential in the perception of speech. However, deficits in speech perception and comprehension do not arise from damage that is restricted to the motor cortex, few functional imaging studies reveal activity in motor cortex during speech perception, and the motor cortex is strongly activated by many different sound categories. Here, we evaluate alternative roles for the motor cortex in spoken communication and suggest a specific role in sensorimotor processing in conversation. We argue that motor-cortex activation it is essential in joint speech, particularly for the timing of turn-taking.
  • Scott, L. J., Muglia, P., Kong, X. Q., Guan, W., Flickinger, M., Upmanyu, R., Tozzi, F., Li, J. Z., Burmeister, M., Absher, D., Thompson, R. C., Francks, C., Meng, F., Antoniades, A., Southwick, A. M., Schatzberg, A. F., Bunney, W. E., Barchas, J. D., Jones, E. G., Day, R. and 13 moreScott, L. J., Muglia, P., Kong, X. Q., Guan, W., Flickinger, M., Upmanyu, R., Tozzi, F., Li, J. Z., Burmeister, M., Absher, D., Thompson, R. C., Francks, C., Meng, F., Antoniades, A., Southwick, A. M., Schatzberg, A. F., Bunney, W. E., Barchas, J. D., Jones, E. G., Day, R., Matthews, K., McGuffin, P., Strauss, J. S., Kennedy, J. L., Middleton, L., Roses, A. D., Watson, S. J., Vincent, J. B., Myers, R. M., Farmer, A. E., Akil, H., Burns, D. K., & Boehnke, M. (2009). Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7501-7506. doi:10.1073/pnas.0813386106.

    Abstract

    Bipolar disorder (BP) is a disabling and often life-threatening disorder that affects approximately 1% of the population worldwide. To identify genetic variants that increase the risk of BP, we genotyped on the Illumina HumanHap550 Beadchip 2,076 bipolar cases and 1,676 controls of European ancestry from the National Institute of Mental Health Human Genetics Initiative Repository, and the Prechter Repository and samples collected in London, Toronto, and Dundee. We imputed SNP genotypes and tested for SNP-BP association in each sample and then performed meta-analysis across samples. The strongest association P value for this 2-study meta-analysis was 2.4 x 10(-6). We next imputed SNP genotypes and tested for SNP-BP association based on the publicly available Affymetrix 500K genotype data from the Wellcome Trust Case Control Consortium for 1,868 BP cases and a reference set of 12,831 individuals. A 3-study meta-analysis of 3,683 nonoverlapping cases and 14,507 extended controls on >2.3 M genotyped and imputed SNPs resulted in 3 chromosomal regions with association P approximately 10(-7): 1p31.1 (no known genes), 3p21 (>25 known genes), and 5q15 (MCTP1). The most strongly associated nonsynonymous SNP rs1042779 (OR = 1.19, P = 1.8 x 10(-7)) is in the ITIH1 gene on chromosome 3, with other strongly associated nonsynonymous SNPs in GNL3, NEK4, and ITIH3. Thus, these chromosomal regions harbor genes implicated in cell cycle, neurogenesis, neuroplasticity, and neurosignaling. In addition, we replicated the reported ANK3 association results for SNP rs10994336 in the nonoverlapping GSK sample (OR = 1.37, P = 0.042). Although these results are promising, analysis of additional samples will be required to confirm that variant(s) in these regions influence BP risk.

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  • Segaert, K., Nygård, G. E., & Wagemans, J. (2009). Identification of everyday objects on the basis of kinetic contours. Vision Research, 49(4), 417-428. doi:10.1016/j.visres.2008.11.012.

    Abstract

    Using kinetic contours derived from everyday objects, we investigated how motion affects object identification. In order not to be distinguishable when static, kinetic contours were made from random dot displays consisting of two regions, inside and outside the object contour. In Experiment 1, the dots were moving in only one of two regions. The objects were identified nearly equally well as soon as the dots either in the figure or in the background started to move. RTs decreased with increasing motion coherence levels and were shorter for complex, less compact objects than for simple, more compact objects. In Experiment 2, objects could be identified when the dots were moving both in the figure and in the background with speed and direction differences between the two. A linear increase in either the speed difference or the direction difference caused a linear decrease in RT for correct identification. In addition, the combination of speed and motion differences appeared to be super-additive.
  • Seidl, A., & Cristia, A. (2008). Developmental changes in the weighting of prosodic cues. Developmental Science, 11, 596-606. doi:10.1111/j.1467-7687.2008.00704.x.

    Abstract

    Previous research has shown that the weighting of, or attention to, acoustic cues at the level of the segment changes over the course of development (Nittrouer & Miller, 1997; Nittrouer, Manning & Meyer, 1993). In this paper we examined changes over the course of development in weighting of acoustic cues at the suprasegmental level. Specifically, we tested English-learning 4-month-olds’ performance on a clause segmentation task when each of three acoustic cues to clausal units was neutralized and contrasted it with performance on a Baseline condition where no cues were manipulated. Comparison with the reported performance of 6-month-olds on the same task (Seidl, 2007) reveals that 4-month-olds weight prosodic cues to clausal boundaries differently than 6-month-olds, relying more heavily on all three correlates of clausal boundaries (pause, pitch and vowel duration) than 6-month-olds do, who rely primarily on pitch. We interpret this as evidence that 4-month-olds use a holistic processing strategy, while 6-month-olds may already be able to attend separately to isolated cues in the input stream and may, furthermore, be able to exploit a language-specific cue weighting. Thus, in a way similar to that in other cognitive domains, infants begin as holistic auditory scene processors and are only later able to process individual auditory cues.
  • Seidl, A., Cristia, A., Bernard, A., & Onishi, K. H. (2009). Allophonic and phonemic contrasts in infants' learning of sound patterns. Language Learning and Development, 5, 191-202. doi:10.1080/15475440902754326.

    Abstract

    French-learning 11-month-old and English-learning 11- and 4-month-old infants were familiarized with consonant–vowel–consonant syllables in which the final consonants were dependent on whether the preceding vowel was oral or nasal. Oral and nasal vowels are present in the ambient language of all participants, but vowel nasality is phonemic (contrastive) in French and allophonic (noncontrastive) in English. After familiarization, infants heard novel syllables that either followed or violated the familiarized patterns. French-learning 11-month-olds and English-learning 4-month-olds displayed a reliable pattern of preference demonstrating learning and generalization of the patterns, while English-learning 11-month-olds oriented equally to syllables following and violating the familiarized patterns. The results are consistent with an experience-driven reduction of attention to allophonic contrasts by as early as 11 months, which influences phonotactic learning.
  • Seifart, F., Drude, S., Franchetto, B., Gasché, J., Golluscio, L., & Manrique, E. (2008). Language documentation and archives in South America. Language Documentation and Conservation, 2(1), 130-140. Retrieved from http://nflrc.hawaii.edu/ldc/June2008/.

    Abstract

    This paper addresses a set of issues related to language documentation that are not often explicitly dealt with in academic publications, yet are highly important for the development and success of this new discipline. These issues include embedding language documentation in the socio-political context not only at the community level but also at the national level, the ethical and technical challenges of digital language archives, and the importance of regional and international cooperation among documentation activities. These issues play a major role in the initiative to set up a network of regional language archives in three South American countries, which this paper reports on. Local archives for data on endangered languages have recently been set up in Iquitos (Peru), Buenos Aires (Argentina), and in various locations in Brazil. An important feature of these is that they provide fast and secure access to linguistic and cultural data for local researchers and the language communities. They also make data safer by allowing for regular update procedures within the network.
  • Sekine, K. (2009). Changes in frame of reference use across the preschool years: A longitudinal study of the gestures and speech produced during route descriptions. Language and Cognitive Processes, 24(2), 218-238. doi:10.1080/01690960801941327.

    Abstract

    This study longitudinally investigated developmental changes in the frame of reference used by children in their gestures and speech. Fifteen children, between 4 and 6 years of age, were asked once a year to describe their route home from their nursery school. When the children were 4 years old, they tended to produce gestures that directly and continuously indicated their actual route in a large gesture space. In contrast, as 6-year-olds, their gestures were segmented and did not match the actual route. Instead, at age 6, the children seemed to create a virtual space in front of themselves to symbolically describe their route. These results indicate that the use of frames of reference develops across the preschool years, shifting from an actual environmental to an abstract environmental frame of reference. Factors underlying the development of frame of reference, including verbal encoding skills and experience, are discussed.
  • Sekine, K. (2008). A review of psychological studies on development of spontaneous gestures in preschool age. The Japanese Journal of Educational Psychology, 56(3), 440-453. doi:10.5926/jjep1953.56.3_440.

    Abstract

    Previous studies of the development of gestures have examined gestures in infants. In recent years, together with the rise of interest in spontaneous gestures accompanied by speech, research on spontaneous gestures in preschool-age children has increased. But little has been reported in terms of systematic developmental changes in children's spontaneous gestures, especially with respect to preschool-age children. The present paper surveys domestic and international research on the development of spontaneous gestures in preschoolers. When gestures seen in infants and preschool-age and older children were categorized, it was found that spontaneous gestures begin to appear together with speech semantically and temporarily by the end of the one-word period; during this same period, gestures that were seen earlier gradually decrease. It is suggested that the development of spontaneous gestures relates to a sentence level, not to a vocabulary level. Based on growth point theory (McNeill, 1992), it is also argued that spontaneous gestures develop with “thinking for speaking” and symbol ability.
  • Senft, G. (2008). The case: The Trobriand Islanders vs H.P. Grice: Kilivila and the Gricean maxims of quality and manner. Anthropos, 103, 139-147.

    Abstract

    The Gricean maxim of Quality “Try to make your contribution one that is true” and his maxim of Manner “Be perspicuous” are not observed in Kilivila, the Austronesian language of the Trobriand Islanders of Papua New Guinea. Speakers of Kilivila metalinguistically differentiate registers of their language. One of these varieties is called biga sopa. This label can be glossed as “joking or lying speech, indirect speech, speech which is not vouched for.” The biga sopa constitutes the default register of Trobriand discourse. This article describes the concept of sopa, presents its features, and discusses and illustrates its functions and use within Trobriand society. The article ends with a discussion of the relevance of Gricean maxims for the research of everyday verbal interaction in Kilivila and a general criticism of these maxims, especially from an anthropological linguistic perspective. [Trobriand Islanders, Gricean maxims, varieties of Kilivila, Kilivila sopa, un-plain speaking]
  • Senft, G. (1994). Ein Vorschlag, wie man standardisiert Daten zum Thema 'Sprache, Kognition und Konzepte des Raumes' in verschiedenen Kulturen erheben kann. Linguistische Berichte, 154, 413-429.
  • Senft, G. (1991). [Review of the book Einführung in die deskriptive Linguistik by Michael Dürr and Peter Schlobinski]. Linguistics, 29, 722-725.
  • Senft, G. (2009). [Review of the book Geschichten und Gesänge von der Insel Nias in Indonesien ed. by Johannes Maria Hämmerle]. Rundbrief - Forum für Mitglieder des Pazifik-Netzwerkes e.V., 78/09, 29-31.
  • Senft, G. (1994). [Review of the book Language, culture and society: An introduction by Zdenek Salzmann]. Man, 29, 756-757.
  • Senft, G. (1991). [Review of the book The sign languages of Aboriginal Australia by Adam Kendon]. Journal of Pragmatics, 15, 400-405. doi:10.1016/0378-2166(91)90040-5.
  • Senft, G. (2008). [Review of the book Expeditionen in die Südsee: Begleitbuch zur Ausstellung und Geschichte der Südsee Sammlung des Ethnologischen Museums ed. by Markus Schindlbeck]. Paideuma, 54, 317-320.
  • Senft, G. (2008). Landscape terms and place names in the Trobriand Islands - The Kaile'una subset. Language Sciences, 30(2/3), 340-361. doi:10.1016/j.langsci.2006.12.001.

    Abstract

    After a brief introduction to the topic the paper first gives an overview of Kilivila landscape terms and then presents the inventory of names for villages, wells, island points, reef-channels and gardens on Kaile’una Island, one of the Trobriand Islands in the Milne Bay Province of Papua New Guinea. The data on the meaning of the place names presented were gathered in 2004 with six male consultants (between the age of 36 and 64 years) living in the village Tauwema on Kaile’una Island. Thus, the list of place names is quite possibly not the complete sample, but it is reasonably representative of the types of Kilivila place names. After discussing the meaning of these terms the paper presents a first attempt to typologically classify and categorize the place names. The paper ends with a critical discussion of the landscape terms and the proposed typology for place names.
  • Senft, G. (1994). Grammaticalisation of body-part terms in Kilivila. Language and Linguistics in Melanesia, 25, 98-99.
  • Senft, G. (1991). Network models to describe the Kilivila classifier system. Oceanic Linguistics, 30, 131-155. Retrieved from http://www.jstor.org/stable/3623085.
  • Senft, G. (1994). Spatial reference in Kilivila: The Tinkertoy Matching Games - A case study. Language and Linguistics in Melanesia, 25, 55-93.
  • Senft, G. (1994). These 'Procrustean' feelings: Some of my problems in describing Kilivila. Semaian, 11, 86-105.
  • Seuren, P. A. M. (2009). Concerning the roots of transformational generative grammar [Review article]. Historiographia Linguistica, 36, 97-115. doi:10.1075/hl.36.1.05seu.
  • Seuren, P. A. M. (1982). De spellingsproblematiek in Suriname: Een inleiding. OSO, 1(1), 71-79.
  • Seuren, P. A. M. (1971). Chomsky, man en werk. De Gids, 134, 298-308.
  • Seuren, P. A. M. (1994). [Review of the Dictionary of St. Lucian Creole, part 1: Kweyol- English', part 2: English-Kweyol compiled by Jones E. Mondesir and ed. by Lawrence D. Carrington]. Linguistics, 32(1), 157-158. doi:10.1515/ling.1991.29.4.719.
  • Seuren, P. A. M. (1973). [Review of the book A comprehensive etymological dictionary of the English language by Ernst Klein]. Neophilologus, 57(4), 423-426. doi:10.1007/BF01515518.
  • Seuren, P. A. M. (1971). [Review of the book Introduction à la grammaire générative by Nicolas Ruwet]. Linguistics, 10(78), 111-120. doi:10.1515/ling.1972.10.78.72.
  • Seuren, P. A. M. (1971). [Review of the book La linguistique synchronique by Andre Martinet]. Linguistics, 10(78), 109-111. doi:10.1515/ling.1972.10.78.72.
  • Seuren, P. A. M. (1973). [Review of the book Philosophy of language by Robert J. Clack and Bertrand Russell]. Foundations of Language, 9(3), 440-441.
  • Seuren, P. A. M. (1973). [Review of the book Semantics. An interdisciplinary reader in philosophy, linguistics and psychology ed. by Danny D. Steinberg and Leon A. Jakobovits]. Neophilologus, 57(2), 198-213. doi:10.1007/BF01514332.
  • Seuren, P. A. M. (1971). [Review of the book Syntaxis by A. Kraak and W. Klooster]. Foundations of Language, 7(3), 441-445.
  • Seuren, P. A. M. (1963). Naar aanleiding van Dr. F. Balk-Smit Duyzentkunst "De Grammatische Functie". Levende Talen, 219, 179-186.
  • Seuren, P. A. M. (1991). Grammatika als algorithme: Rekenen met taal. Koninklijke Nederlandse Akademie van Wetenschappen. Mededelingen van de Afdeling Letterkunde, Nieuwe Reeks, 54(2), 25-63.
  • Seuren, P. A. M. (1982). Internal variability in competence. Linguistische Berichte, 77, 1-31.
  • Seuren, P. A. M. (2009). The clitics mechanism in French and Italian. Probus, 21(1), 83-142. doi:10.1515/prbs.2009.004.

    Abstract

    The article concentrates on the question of the composition, the internal ordering and the placement of clitic-clusters (C-clusters) in French and Italian, though clitic data from other languages are drawn in occasionally. The system proposed is top-down transformational, in the terms of Semantic Syntax (Seuren, Blackwell, 1996). Clitics are taken to originate in underlying structure as canonical argument terms or adverbial constituents of clauses. During the process of transformation from semantic to surface form, nonfocus, nonsubject, pronominal argument terms are assigned values for the features of animacy ([±an]), dative status ([±dat]) and reflexivity ([±refl]). On the basis of these, the rule feature cm, inducing clitic movement, is assigned or withheld. Plus-values increase, and minus-values reduce, the “semantic weight” of the clitics in question. Pronouns without the feature cm are not cliticised and stay in their canonical term position in their full phonological form. Pronouns with the feature cm are attached to the nearest verb form giving rise to clitic clusters, which accounts for the composition of well-formed C-clusters. The attachment of clitics to a cluster occurs in a fixed order, which accounts for the ordering of clitics in well-formed clusters. Branching directionality, together with a theory of complementation, accounts for the placement of C-clusters. Clitics often take on a reduced phonological form. It is argued that, in French and Italian, which are languages with a right-branching syntax and a left-branching flectional morphology, postverbal clitics, or enclitics, are part of left-branching structures and hence fit naturally into the morphology. They are best categorised as affixes. Occasionally, as in Italian glielo, dative clitics (e.g., gli) turn preceding lighter clitics (e.g., lo) into affixes, resulting in the left-branching structure glielo, where -lo is an affix. In a brief Intermezzo, instances are shown of the irregular but revealing lui-le-lui phenomenon in French, and its much less frequent analog in Italian. On these assumptions, supported by the official orthographies, the clitic systems of French and Italian largely coincide. This new analysis of the facts in question invites further reflection on the interface between syntax and morphology. The final section deals with reflexive clitics. There, the system begins to be unable to account for the observed facts. At this end, therefore, the system is allowed to remain fraying, till further research brings greater clarity.
  • Seuren, P. A. M. (1994). Soaps and serials. Journal of Pidgin and Creole Languages, 9(1), 131-149. doi:10.1075/jpcl.9.1.18seu.
  • Seuren, P. A. M., & Hamans, C. (2009). Semantic conditioning of syntactic rules: Evidentiality and auxiliation in English and Dutch. Folia Linguistica, 43(1), 135-169. doi:10.1515/FLIN.2009.004.

    Abstract

    Ever since the category of evidentiality has been identified in the verbal grammar of certain languages, it has been assumed that evidentiality plays no role in the grammars of those languages that have not incorporated it into their verb morphology or at least their verb clusters. The present paper attempts to show that even if evidentiality is not visible in the verbal grammar of English and Dutch, it appears to be a motivating factor, both historically and synchronically, in the process whereby evidential predicates are made to play a subordinate syntactic role with regard to their embedded subject clause. This process, known as AUXILIATION (Kuteva 2001), appears to manifest itself in a variety of, often successive, grammatical processes or rules, such as Subject-to-Subject Raising (the subject of the embedded clause becomes the subject of the main verb, as in John is likely to be late), V-ING (as in The man stopped breathing), Incorporation-by-Lowering (the evidential main verb is lowered on to the V-constituent of the embedded subject clause, as in John may have left), or Incorporation-by-Raising (also known as Predicate Raising), not or hardly attested in English but dominant in Dutch. A list is provided of those English (and Dutch) predicates that induce one of the above-mentioned auxiliation rules and it is checked how many of those have an evidential meaning. This is set off against evidential predicates that do not induce an auxiliation rule. It results that, for English and Dutch, lexical evidentiality is a powerful determinant for the induction of syntactic auxiliation.
  • Seuren, P. A. M. (1973). Zero-output rules. Foundations of Language, 10(2), 317-328.

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