Publications

Displaying 301 - 400 of 990
  • Guarin, A., Haun, D. B. M., & Messner, D. (2013). Behavioral dimensions of international cooperation. Duisburg: Käte Hamburger Kolleg / Centre for Global Cooperation Research. doi:10.2139/ssrn.2361423.
  • Guerrero, L., & Van Valin Jr., R. D. (2004). Yaqui and the analysis of primary object languages. International Journal of American Linguistics, 70(3), 290-319. doi:10.1086/425603.

    Abstract

    The central topic of this study is to investigate three- and four-place predicate in Yaqui, which are characterized by having multiple object arguments. As with other Southern Uto-Aztecan languages, it has been said that Yaqui follows the Primary/Secondary Object pattern (Dryer 1986). Actually, Yaqui presents three patterns: verbs like nenka ‘sell’ follow the direct–indirect object pattern, verbs like miika ‘give’ follow the primary object pattern, and verbs like chijakta ‘sprinkle’ follow the locative alternation pattern; the primary object pattern is the exclusive one found with derived verbs. This paper shows that the contrast between direct object and primary object languages is not absolute but rather one of degree, and hence two “object” selection principles are needed to explain this mixed system. The two principles are not limited to Yaqui but are found in other languages as well, including English.
  • Gullberg, M. (2004). [Review of the book Pointing: Where language, culture and cognition meet ed. by Sotaro Kita]. Gesture, 4(2), 235-248. doi:10.1075/gest.4.2.08gul.
  • Gullberg, M. (1998). Gesture as a communication strategy in second language discourse: A study of learners of French and Swedish. Lund: Lund University Press.

    Abstract

    Gestures are often regarded as the most typical compensatory device used by language learners in communicative trouble. Yet gestural solutions to communicative problems have rarely been studied within any theory of second language use. The work pre­sented in this volume aims to account for second language learners’ strategic use of speech-associated gestures by combining a process-oriented framework for communi­cation strategies with a cognitive theory of gesture. Two empirical studies are presented. The production study investigates Swedish lear­ners of French and French learners of Swedish and their use of strategic gestures. The results, which are based on analyses of both individual and group behaviour, contradict popular opinion as well as theoretical assumptions from both fields. Gestures are not primarily used to replace speech, nor are they chiefly mimetic. Instead, learners use gestures with speech, and although they do exploit mimetic gestures to solve lexical problems, they also use more abstract gestures to handle discourse-related difficulties and metalinguistic commentary. The influence of factors such as proficiency, task, culture, and strategic competence on gesture use is discussed, and the oral and gestural strategic modes are compared. In the evaluation study, native speakers’ assessments of learners’ gestures, and the potential effect of gestures on evaluations of proficiency are analysed and discussed in terms of individual communicative style. Compensatory gestures function at multiple communicative levels. This has implica­tions for theories of communication strategies, and an expansion of the existing frameworks is discussed taking both cognitive and interactive aspects into account.
  • Gullberg, M., & Holmqvist, K. (1999). Keeping an eye on gestures: Visual perception of gestures in face-to-face communication. Pragmatics & Cognition, 7(1), 35-63. doi:10.1075/pc.7.1.04gul.

    Abstract

    Since listeners usually look at the speaker's face, gestural information has to be absorbed through peripheral visual perception. In the literature, it has been suggested that listeners look at gestures under certain circumstances: 1) when the articulation of the gesture is peripheral; 2) when the speech channel is insufficient for comprehension; and 3) when the speaker him- or herself indicates that the gesture is worthy of attention. The research here reported employs eye tracking techniques to study the perception of gestures in face-to-face interaction. The improved control over the listener's visual channel allows us to test the validity of the above claims. We present preliminary findings substantiating claims 1 and 3, and relate them to theoretical proposals in the literature and to the issue of how visual and cognitive attention are related.
  • Gussenhoven, C., & Zhou, W. (2013). Revisiting pitch slope and height effects on perceived duration. In Proceedings of INTERSPEECH 2013: 14th Annual Conference of the International Speech Communication Association (pp. 1365-1369).

    Abstract

    The shape of pitch contours has been shown to have an effect on the perceived duration of vowels. For instance, vowels with high level pitch and vowels with falling contours sound longer than vowels with low level pitch. Depending on whether the
    comparison is between level pitches or between level and dynamic contours, these findings have been interpreted in two ways. For inter-level comparisons, where the duration results are the reverse of production results, a hypercorrection strategy in production has been proposed [1]. By contrast, for comparisons between level pitches and dynamic contours, the
    longer production data for dynamic contours have been held responsible. We report an experiment with Dutch and Chinese listeners which aimed to show that production data and perception data are each other’s opposites for high, low, falling and rising contours. We explain the results, which are consistent with earlier findings, in terms of the compensatory listening strategy of [2], arguing that the perception effects are due to a perceptual compensation of articulatory strategies and
    constraints, rather than that differences in production compensate for psycho-acoustic perception effects.
  • De Haan, E., & Hagoort, P. (2004). Het brein in beeld. In B. Deelman, P. Eling, E. De Haan, & E. Van Zomeren (Eds.), Klinische neuropsychologie (pp. 82-98). Amsterdam: Boom.
  • Hagoort, P., & Brown, C. M. (1994). Brain responses to lexical ambiguity resolution and parsing. In C. Clifton Jr, L. Frazier, & K. Rayner (Eds.), Perspectives on sentence processing (pp. 45-81). Hilsdale NY: Lawrence Erlbaum Associates.
  • Hagoort, P. (1994). Afasie als een tekort aan tijd voor spreken en verstaan. De Psycholoog, 4, 153-154.
  • Hagoort, P. (1998). De electrofysiologie van taal: Wat hersenpotentialen vertellen over het menselijk taalvermogen. Neuropraxis, 2, 223-229.
  • Hagoort, P. (1998). De spreker als sprinter. Psychologie, 17, 48-49.
  • Hagoort, P. (1999). De toekomstige eeuw zonder psychologie. Psychologie Magazine, 18, 35-36.
  • Hagoort, P. (2004). Er is geen behoefte aan trompetten als gordijnen. In H. Procee, H. Meijer, P. Timmerman, & R. Tuinsma (Eds.), Bij die wereld wil ik horen! Zesendertig columns en drie essays over de vorming tot academicus (pp. 78-80). Amsterdam: Boom.
  • Hagoort, P., Hald, L. A., Bastiaansen, M. C. M., & Petersson, K. M. (2004). Integration of word meaning and world knowledge in language comprehension. Science, 304(5669), 438-441. doi:10.1126/science.1095455.

    Abstract

    Although the sentences that we hear or read have meaning, this does not necessarily mean that they are also true. Relatively little is known about the critical brain structures for, and the relative time course of, establishing the meaning and truth of linguistic expressions. We present electroencephalogram data that show the rapid parallel integration of both semantic and world
    knowledge during the interpretation of a sentence. Data from functional magnetic resonance imaging revealed that the left inferior prefrontal cortex is involved in the integration of both meaning and world knowledge. Finally, oscillatory brain responses indicate that the brain keeps a record of what makes a sentence hard to interpret.
  • Hagoort, P. (2004). Het zwarte gat tussen brein en bewustzijn. In N. Korteweg (Ed.), De oorsprong: Over het ontstaan van het leven en alles eromheen (pp. 107-124). Amsterdam: Boom.
  • Hagoort, P., & Brown, C. M. (1999). Gender electrified: ERP evidence on the syntactic nature of gender processing. Journal of Psycholinguistic Research, 28(6), 715-728. doi:10.1023/A:1023277213129.

    Abstract

    The central issue of this study concerns the claim that the processing of gender agreement in online sentence comprehension is a syntactic rather than a conceptual/semantic process. This claim was tested for the grammatical gender agreement in Dutch between the definite article and the noun. Subjects read sentences in which the definite article and the noun had the same gender and sentences in which the gender agreement was violated, While subjects read these sentences, their electrophysiological activity was recorded via electrodes placed on the scalp. Earlier research has shown that semantic and syntactic processing events manifest themselves in different event-related brain potential (ERP) effects. Semantic integration modulates the amplitude of the so-called N400.The P600/SPS is an ERP effect that is more sensitive to syntactic processes. The violation of grammatical gender agreement was found to result in a P600/SPS. For violations in sentence-final position, an additional increase of the N400 amplitude was observed. This N400 effect is interpreted as resulting from the consequence of a syntactic violation for the sentence-final wrap-up. The overall pattern of results supports the claim that the on-line processing of gender agreement information is not a content driven but a syntactic-form driven process.
  • Hagoort, P. (2013). MUC (Memory, Unification, Control) and beyond. Frontiers in Psychology, 4: 416. doi:10.3389/fpsyg.2013.00416.

    Abstract

    A neurobiological model of language is discussed that overcomes the shortcomings of the classical Wernicke-Lichtheim-Geschwind model. It is based on a subdivision of language processing into three components: Memory, Unification, and Control. The functional components as well as the neurobiological underpinnings of the model are discussed. In addition, the need for extension of the model beyond the classical core regions for language is shown. Attentional networks as well as networks for inferential processing are crucial to realize language comprehension beyond single word processing and beyond decoding propositional content. It is shown that this requires the dynamic interaction between multiple brain regions.
  • Hagoort, P. (1998). Hersenen en taal in onderzoek en praktijk. Neuropraxis, 6, 204-205.
  • Hagoort, P. (1994). Het brein op een kier: Over hersenen gesproken. Psychologie, 13, 42-46.
  • Hagoort, P., & Brown, C. M. (1999). The consequences of the temporal interaction between syntactic and semantic processes for haemodynamic studies of language. NeuroImage, 9, S1024-S1024.
  • Hagoort, P., Brown, C. M., & Osterhout, L. (1999). The neurocognition of syntactic processing. In C. M. Brown, & P. Hagoort (Eds.), The neurocognition of language (pp. 273-317). Oxford: Oxford University Press.
  • Hagoort, P., Ramsey, N., Rutten, G.-J., & Van Rijen, P. (1999). The role of the left anterior temporal cortex in language processing. Brain and Language, 69, 322-325. doi:10.1006/brln.1999.2169.
  • Hagoort, P. (1998). The shadows of lexical meaning in patients with semantic impairments. In B. Stemmer, & H. Whitaker (Eds.), Handbook of neurolinguistics (pp. 235-248). New York: Academic Press.
  • Hagoort, P., & Poeppel, D. (2013). The infrastructure of the language-ready brain. In M. A. Arbib (Ed.), Language, music, and the brain: A mysterious relationship (pp. 233-255). Cambridge, MA: MIT Press.

    Abstract

    This chapter sketches in very general terms the cognitive architecture of both language comprehension and production, as well as the neurobiological infrastructure that makes the human brain ready for language. Focus is on spoken language, since that compares most directly to processing music. It is worth bearing in mind that humans can also interface with language as a cognitive system using sign and text (visual) as well as Braille (tactile); that is to say, the system can connect with input/output processes in any sensory modality. Language processing consists of a complex and nested set of subroutines to get from sound to meaning (in comprehension) or meaning to sound (in production), with remarkable speed and accuracy. The fi rst section outlines a selection of the major constituent operations, from fractionating the input into manageable units to combining and unifying information in the construction of meaning. The next section addresses the neurobiological infrastructure hypothesized to form the basis for language processing. Principal insights are summarized by building on the notion of “brain networks” for speech–sound processing, syntactic processing, and the construction of meaning, bearing in mind that such a neat three-way subdivision overlooks important overlap and shared mechanisms in the neural architecture subserving language processing. Finally, in keeping with the spirit of the volume, some possible relations are highlighted between language and music that arise from the infrastructure developed here. Our characterization of language and its neurobiological foundations is necessarily selective and brief. Our aim is to identify for the reader critical questions that require an answer to have a plausible cognitive neuroscience of language processing.
  • Hagoort, P., Indefrey, P., Brown, C. M., Herzog, H., Steinmetz, H., & Seitz, R. J. (1999). The neural circuitry involved in the reading of german words and pseudowords: A PET study. Journal of Cognitive Neuroscience, 11(4), 383-398. doi:10.1162/089892999563490.

    Abstract

    Silent reading and reading aloud of German words and pseudowords were used in a PET study using (15O)butanol to examine the neural correlates of reading and of the phonological conversion of legal letter strings, with or without meaning.
    The results of 11 healthy, right-handed volunteers in the age range of 25 to 30 years showed activation of the lingual gyri during silent reading in comparison with viewing a fixation cross. Comparisons between the reading of words and pseudowords suggest the involvement of the middle temporal gyri in retrieving both the phonological and semantic code for words. The reading of pseudowords activates the left inferior frontal gyrus, including the ventral part of Broca’s area, to a larger extent than the reading of words. This suggests that this area might be involved in the sublexical conversion of orthographic input strings into phonological output codes. (Pre)motor areas were found to be activated during both silent reading and reading aloud. On the basis of the obtained activation patterns, it is hypothesized that the articulation of high-frequency syllables requires the retrieval of their concomitant articulatory gestures from the SMA and that the articulation of lowfrequency syllables recruits the left medial premotor cortex.
  • Hagoort, P., & Meyer, A. S. (2013). What belongs together goes together: the speaker-hearer perspective. A commentary on MacDonald's PDC account. Frontiers in Psychology, 4: 228. doi:10.3389/fpsyg.2013.00228.

    Abstract

    First paragraph:
    MacDonald (2013) proposes that distributional properties of language and processing biases in language comprehension can to a large extent be attributed to consequences of the language production process. In essence, the account is derived from the principle of least effort that was formulated by Zipf, among others (Zipf, 1949; Levelt, 2013). However, in Zipf's view the outcome of the least effort principle was a compromise between least effort for the speaker and least effort for the listener, whereas MacDonald puts most of the burden on the production process.
  • Hagoort, P. (1999). The uniquely human capacity for language communication: from 'pope' to [po:p] in half a second. In J. Russell, M. Murphy, T. Meyering, & M. Arbib (Eds.), Neuroscience and the person: Scientific perspectives on divine action (pp. 45-56). California: Berkeley.
  • Hall, S., Rumney, L., Holler, J., & Kidd, E. (2013). Associations among play, gesture and early spoken language acquisition. First Language, 33, 294-312. doi:10.1177/0142723713487618.

    Abstract

    The present study investigated the developmental interrelationships between play, gesture use and spoken language development in children aged 18–31 months. The children completed two tasks: (i) a structured measure of pretend (or ‘symbolic’) play and (ii) a measure of vocabulary knowledge in which children have been shown to gesture. Additionally, their productive spoken language knowledge was measured via parental report. The results indicated that symbolic play is positively associated with children’s gesture use, which in turn is positively associated with spoken language knowledge over and above the influence of age. The tripartite relationship between gesture, play and language development is discussed with reference to current developmental theory.
  • Hammarström, H., & O'Connor, L. (2013). Dependency sensitive typological distance. In L. Borin, & A. Saxena (Eds.), Approaches to measuring linguistic differences (pp. 337-360). Berlin: Mouton de Gruyter.
  • Hammarström, H. (2013). Noun class parallels in Kordofanian and Niger-Congo: Evidence of genealogical inheritance? In T. C. Schadeberg, & R. M. Blench (Eds.), Nuba Mountain Language Studies (pp. 549-570). Köln: Köppe.
  • Hanique, I., Aalders, E., & Ernestus, M. (2013). How robust are exemplar effects in word comprehension? The mental lexicon, 8, 269-294. doi:10.1075/ml.8.3.01han.

    Abstract

    This paper studies the robustness of exemplar effects in word comprehension by means of four long-term priming experiments with lexical decision tasks in Dutch. A prime and target represented the same word type and were presented with the same or different degree of reduction. In Experiment 1, participants heard only a small number of trials, a large proportion of repeated words, and stimuli produced by only one speaker. They recognized targets more quickly if these represented the same degree of reduction as their primes, which forms additional evidence for the exemplar effects reported in the literature. Similar effects were found for two speakers who differ in their pronunciations. In Experiment 2, with a smaller proportion of repeated words and more trials between prime and target, participants recognized targets preceded by primes with the same or a different degree of reduction equally quickly. Also, in Experiments 3 and 4, in which listeners were not exposed to one but two types of pronunciation variation (reduction degree and speaker voice), no exemplar effects arose. We conclude that the role of exemplars in speech comprehension during natural conversations, which typically involve several speakers and few repeated content words, may be smaller than previously assumed.
  • Hanique, I., Ernestus, M., & Schuppler, B. (2013). Informal speech processes can be categorical in nature, even if they affect many different words. Journal of the Acoustical Society of America, 133, 1644-1655. doi:10.1121/1.4790352.

    Abstract

    This paper investigates the nature of reduction phenomena in informal speech. It addresses the question whether reduction processes that affect many word types, but only if they occur in connected informal speech, may be categorical in nature. The focus is on reduction of schwa in the prefixes and on word-final /t/ in Dutch past participles. More than 2000 tokens of past participles from the Ernestus Corpus of Spontaneous Dutch and the Spoken Dutch Corpus (both from the interview and read speech component) were transcribed automatically. The results demonstrate that the presence and duration of /t/ are affected by approximately the same phonetic variables, indicating that the absence of /t/ is the extreme result of shortening, and thus results from a gradient reduction process. Also for schwa, the data show that mainly phonetic variables influence its reduction, but its presence is affected by different and more variables than its duration, which suggests that the absence of schwa may result from gradient as well as categorical processes. These conclusions are supported by the distributions of the segments’ durations. These findings provide evidence that reduction phenomena which affect many words in informal conversations may also result from categorical reduction processes.
  • Hanique, I. (2013). Mental representation and processing of reduced words in casual speech. PhD Thesis, Radboud University Nijmegen, Nijmegen.
  • Haun, D. B. M., & Wertenbruch, M. (2013). Forschungen und Entwicklungen zum Konzept der Ehre als Potential für Konflikte zwischen Kulturen bzw. als Hindernis für Integration. Wien: Österreichischen Integrationsfonds.
  • Haun, D. B. M., Van Leeuwen, E. J. C., & Edelson, M. G. (2013). Majority influence in children and other animals. Developmental Cognitive Neuroscience, 3, 61-71. doi:10.1016/j.dcn.2012.09.003.

    Abstract

    We here review existing evidence for majority influences in children under the age of ten years and comparable studies with animals ranging from fish to apes. Throughout the review, we structure the discussion surrounding majority influences by differentiating the behaviour of individuals in the presence of a majority and the underlying mechanisms and motivations. Most of the relevant research to date in both developmental psychology and comparative psychology has focused on the behavioural outcomes, where a multitude of mechanisms could be at play. We further propose that interpreting cross-species differences in behavioural patterns is difficult without considering the psychology of the individual. Some attempts at this have been made both in developmental psychology and comparative psychology. We propose that physiological measures should be used to subsidize behavioural studies in an attempt to understand the composition of mechanisms and motivations underlying majority influence. We synthesize the relevant evidence on human brain function in order to provide a framework for future investigation in this area. In addition to streamlining future research efforts, we aim to create a conceptual platform for productive exchanges across the related disciplines of developmental and comparative psychology.
  • Haun, D. B. M., & Over, H. (2013). Like me: A homophily-based account of human culture. In P. J. Richerson, & M. H. Christiansen (Eds.), Cultural Evolution: Society, technology, language, and religion (pp. 75-85). Cambridge, MA: MIT Press.
  • Hayano, K. (2013). Territories of knowledge in Japanese conversation. PhD Thesis, Radboud University Nijmegen, Nijmegen.

    Abstract

    This thesis focuses on one aspect of interactional competence: competence to manage knowledge distribution in conversation. In order to be considered competent in everyday interaction, participants need not only to index one another's knowledge states but also to engage in dynamic negotiation of knowledge distribution. Adopting the methodology of conversation analysis, the thesis investigates how participants' orientations to knowledge distribution, 'epistemicity', are manifested. The thesis examines three interactional environments: assessment sequences, informing sequences and polar question-answer sequences. A systematic analysis reveals that interactants orient to different aspects of knowledge in different environments, employing different grammatical resources. When they assess an object, they are concerned about who possesses 'epistemic primacy'. Japanese final particles and the practices of intensification serve together to claim epistemic primacy and provide support for the claim. It is also reported that interactants are oriented to achieve 'epistemic congruence' − consensus regarding how knowledge is distributed among them. When one provides the other with new information, the exchange commonly develops into a four-turn sequence, instead of a minimal adjacency pair. It is shown that this sequence organization allows interactants to achieve a balance between territories of experience, affiliation and empathy. In polar question-answer sequences, how (un)expected or novel a given piece of information is becomes an issue. Answers are found to be formulated such that they adopt epistemic stances that are assertive enough to match the level of (un)certainty expressed by questioners. The thesis contributes to our understanding of how social interaction is organized. It becomes clear from the findings that a wide range of aspects of language use and interactional organization are dominated by interactants' orientations to epistemicity. Participants manage knowledge distribution in everyday interaction, which may be the most fundamental means of managing their social statuses and relations.

    Additional information

    full text via Radboud Repository
  • Hayano, K. (2004). Kaiwa ni okeru ninshikiteki ken’i no koushou: Shuujoshi yo, ne, odoroki hyouji no bunpu to kinou [Negotiation of Epistemic Authority in Conversation: on the use of final particles yo, ne and surprise markers]. Studies in Pragmatics, 6, 17-28.
  • Hayano, K. (2013). Question design in conversation. In J. Sidnell, & T. Stivers (Eds.), The handbook of conversation analysis (pp. 395-414). Malden, MA: Wiley-Blackwell. doi:10.1002/9781118325001.ch19.

    Abstract

    This chapter contains sections titled: Introduction Questions Questioning and the Epistemic Gradient Presuppositions, Agenda Setting and Preferences Social Actions Implemented by Questions Questions as Building Blocks of Institutional Activities Future Directions
  • Heidlmayr, K., Moutier, S., Hemforth, B., Courtin, C., Tanzmeister, R., & Isel, F. (2013). Successive bilingualism and executive functions: The effect of second language use on inhibitory control in a behavioural Stroop Colour Wordtask. Bilingualism: Language and Cognition, 17(3), 630-645. doi:dx.doi.org/10.1017/S1366728913000539.

    Abstract

    Here we examined the role of bilingualism on cognitive inhibition using the Stroop Colour Word task. Our hypothesis was that the frequency of use of a second language (L2) in the daily life of successive bilingual individuals impacts the efficiency of their inhibitory control mechanism. Thirty-three highly proficient successive French–German bilinguals, living either in a French or in a German linguistic environment, performed a Stroop task on both French and German words. Moreover, 31 French monolingual individuals were also tested with French words. We showed that the bilingual advantage was (i) reinforced by the use of a third language, and (ii) modulated by the duration of immersion in a second language environment. This suggests that top–down inhibitory control is most involved at the beginning of immersion. Taken together, the present findings lend support to the psycholinguistic models of bilingual language processing that postulate that top–down active inhibition is involved in language control.
  • Heritage, J., & Stivers, T. (1999). Online commentary in acute medical visits: A method of shaping patient expectations. Social Science and Medicine, 49(11), 1501-1517. doi:10.1016/S0277-9536(99)00219-1.
  • Hilbrink, E., Sakkalou, E., Ellis-Davies, K., Fowler, N., & Gattis, M. (2013). Selective and faithful imitation at 12 and 15 months. Developmental Science., 16(6), 828-840. doi:10.1111/desc.12070.

    Abstract

    Research on imitation in infancy has primarily focused on what and when infants imitate. More recently, however, the question why infants imitate has received renewed attention, partly motivated by the finding that infants sometimes selectively imitate the actions of others and sometimes faithfully imitate, or overimitate, the actions of others. The present study evaluates the hypothesis that this varying imitative behavior is related to infants' social traits. To do so, we assessed faithful and selective imitation longitudinally at 12 and 15 months, and extraversion at 15 months. At both ages, selective imitation was dependent on the causal structure of the act. From 12 to 15 months, selective imitation decreased while faithful imitation increased. Furthermore, infants high in extraversion were more faithful imitators than infants low in extraversion. These results demonstrate that the onset of faithful imitation is earlier than previously thought, but later than the onset of selective imitation. The observed relation between extraversion and faithful imitation supports the hypothesis that faithful imitation is driven by the social motivations of the infant. We call this relation the King Louie Effect: like the orangutan King Louie in The Jungle Book, infants imitate faithfully due to a growing interest in the interpersonal nature of interactions.
  • Hinds, D. A., McMahon, G., Kiefer, A. K., Do, C. B., Eriksson, N., Evans, D. M., St Pourcain, B., Ring, S. M., Mountain, J. L., Francke, U., Davey-Smith, G., Timpson, N. J., & Tung, J. Y. (2013). A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat Genet, 45(8), 907-911. doi:10.1038/ng.2686.

    Abstract

    Allergic disease is very common and carries substantial public-health burdens. We conducted a meta-analysis of genome-wide associations with self-reported cat, dust-mite and pollen allergies in 53,862 individuals. We used generalized estimating equations to model shared and allergy-specific genetic effects. We identified 16 shared susceptibility loci with association P<5×10(-8), including 8 loci previously associated with asthma, as well as 4p14 near TLR1, TLR6 and TLR10 (rs2101521, P=5.3×10(-21)); 6p21.33 near HLA-C and MICA (rs9266772, P=3.2×10(-12)); 5p13.1 near PTGER4 (rs7720838, P=8.2×10(-11)); 2q33.1 in PLCL1 (rs10497813, P=6.1×10(-10)), 3q28 in LPP (rs9860547, P=1.2×10(-9)); 20q13.2 in NFATC2 (rs6021270, P=6.9×10(-9)), 4q27 in ADAD1 (rs17388568, P=3.9×10(-8)); and 14q21.1 near FOXA1 and TTC6 (rs1998359, P=4.8×10(-8)). We identified one locus with substantial evidence of differences in effects across allergies at 6p21.32 in the class II human leukocyte antigen (HLA) region (rs17533090, P=1.7×10(-12)), which was strongly associated with cat allergy. Our study sheds new light on the shared etiology of immune and autoimmune disease.
  • Hofmeister, P., & Norcliffe, E. (2013). Does resumption facilitate sentence comprehension? In P. Hofmeister, & E. Norcliffe (Eds.), The core and the periphery: Data-driven perspectives on syntax inspired by Ivan A. Sag (pp. 225-246). Stanford, CA: CSLI Publications.
  • Hofmeister, P., & Norcliffe, E. (Eds.). (2013). The core and the periphery: Data-driven perspectives on syntax inspired by Ivan A. Sag. Stanford, CA: CSLI publications.

    Abstract

    This book is a collection of papers inspired by the linguistics career of Ivan Sag, written to celebrate his many contributions to the field. Ivan has been a professor of linguistics at Stanford University since 1979, has been the directory of the Symbolic Systems program (2005-2009), has authored, co-authored, or edited fifteen volumes in linguistics, and has been at the forefront of non-transformational approaches to syntax. Reflecting the breath of Ivan's theoretical interests and approaches to linguistic problems, the papers here tackle a range of grammar-related issues using corpora, intuitions, and laboratory experiments. They are united by their use of and commitment to rich datasets and the shared perspective that the best theories of grammar attempt to account for the full diversity and complexity of language data.
  • Holler, J., Schubotz, L., Kelly, S., Schuetze, M., Hagoort, P., & Ozyurek, A. (2013). Here's not looking at you, kid! Unaddressed recipients benefit from co-speech gestures when speech processing suffers. In M. Knauff, M. Pauen, I. Sebanz, & I. Wachsmuth (Eds.), Proceedings of the 35th Annual Meeting of the Cognitive Science Society (CogSci 2013) (pp. 2560-2565). Austin, TX: Cognitive Science Society. Retrieved from http://mindmodeling.org/cogsci2013/papers/0463/index.html.

    Abstract

    In human face-to-face communication, language comprehension is a multi-modal, situated activity. However, little is known about how we combine information from these different modalities, and how perceived communicative intentions, often signaled through visual signals, such as eye
    gaze, may influence this processing. We address this question by simulating a triadic communication context in which a
    speaker alternated her gaze between two different recipients. Participants thus viewed speech-only or speech+gesture
    object-related utterances when being addressed (direct gaze) or unaddressed (averted gaze). Two object images followed
    each message and participants’ task was to choose the object that matched the message. Unaddressed recipients responded significantly slower than addressees for speech-only
    utterances. However, perceiving the same speech accompanied by gestures sped them up to a level identical to
    that of addressees. That is, when speech processing suffers due to not being addressed, gesture processing remains intact and enhances the comprehension of a speaker’s message
  • Holler, J., Turner, K., & Varcianna, T. (2013). It's on the tip of my fingers: Co-speech gestures during lexical retrieval in different social contexts. Language and Cognitive Processes, 28(10), 1509-1518. doi:10.1080/01690965.2012.698289.

    Abstract

    The Lexical Retrieval Hypothesis proposes that gestures function at the level of speech production, aiding in the retrieval of lexical items from the mental lexicon. However, empirical evidence for this account is mixed, and some critics argue that a more likely function of gestures during lexical retrieval is a communicative one. The present study was designed to test these predictions against each other by keeping lexical retrieval difficulty constant while varying social context. Participants' gestures were analysed during tip of the tongue experiences when communicating with a partner face-to-face (FTF), while being separated by a screen, or on their own by speaking into a voice recorder. The results show that participants in the FTF context produced significantly more representational gestures than participants in the solitary condition. This suggests that, even in the specific context of lexical retrieval difficulties, representational gestures appear to play predominantly a communicative role.

    Files private

    Request files
  • Holler, J. (2004). Semantic and pragmatic aspects of representational gestures: Towards a unified model of communication in talk. PhD Thesis, University of Manchester, Manchester.
  • Holler, J., & Beattie, G. (2004). The interaction of iconic gesture and speech. In A. Cammurri, & G. Volpe (Eds.), Lecture Notes in Computer Science, 5th International Gesture Workshop, Genova, Italy, 2003; Selected Revised Papers (pp. 63-69). Heidelberg: Springer Verlag.
  • Hömke, P., Majid, A., & Boroditsky, L. (2013). Reversing the direction of time: Does the visibility of spatial representations of time shape temporal focus? Proceedings of the Master's Program Cognitive Neuroscience, 8(1), 40-54. Retrieved from http://www.ru.nl/master/cns/journal/archive/volume-8-issue-1/print-edition/.

    Abstract

    While people around the world mentally represent time in terms of space, there is substantial cross-cultural
    variability regarding which temporal constructs are mapped onto which parts in space. Do particular spatial
    layouts of time – as expressed through metaphors in language – shape temporal focus? We trained native
    English speakers to use spatiotemporal metaphors in a way such that the flow of time is reversed, representing
    the future behind the body (out of visible space) and the past ahead of the body (within visible space). In a
    task measuring perceived relevance of past events, people considered past events and present (or immediate
    past) events to be more relevant after using the reversed metaphors compared to a control group that used canonical metaphors spatializing the past behind and the future ahead of the body (Experiment 1). In a control measure in which temporal information was removed, this effect disappeared (Experiment 2). Taken
    together, these findings suggest that the degree to which people focus on the past may be shaped by the
    visibility of the past in spatiotemporal metaphors used in language.
  • Hoogman, M., Onnink, M., Coolen, R., Aarts, E., Kan, C., Arias Vasquez, A., Buitelaar, J., & Franke, B. (2013). The dopamine transporter haplotype and reward-related striatal responses in adult ADHD. European Neuropsychopharmacology, 23, 469-478. doi:10.1016/j.euroneuro.2012.05.011.

    Abstract

    Attention deficit/hyperactivity disorder (ADHD) is a highly heritable disorder and several genes increasing disease risk have been identified. The dopamine transporter gene, SLC6A3/DAT1, has been studied most extensively in ADHD research. Interestingly, a different haplotype of this gene (formed by genetic variants in the 3' untranslated region and intron 8) is associated with childhood ADHD (haplotype 10-6) and adult ADHD (haplotype 9-6). The expression of DAT1 is highest in striatal regions in the brain. This part of the brain is of interest to ADHD because of its role in reward processing is altered in ADHD patients; ADHD patients display decreased striatal activation during reward processing. To better understand how the DAT1 gene exerts effects on ADHD, we studied the effect of this gene on reward-related brain functioning in the area of its highest expression in the brain, the striatum, using functional magnetic resonance imaging. In doing so, we tried to resolve inconsistencies observed in previous studies of healthy individuals and ADHD-affected children. In a sample of 87 adult ADHD patients and 77 healthy comparison subjects, we confirmed the association of the 9-6 haplotype with adult ADHD. Striatal hypoactivation during the reward anticipation phase of a monetary incentive delay task in ADHD patients was again shown, but no significant effects of DAT1 on striatal activity were found. Although the importance of the DAT1 haplotype as a risk factor for adult ADHD was again demonstrated in this study, the mechanism by which this gene increases disease risk remains largely unknown.

    Additional information

    mmc1.zip
  • Horemans, I., & Schiller, N. O. (2004). Form-priming effects in nonword naming. Brain and Language, 90(1-3), 465-469. doi:10.1016/S0093-934X(03)00457-7.

    Abstract

    Form-priming effects from sublexical (syllabic or segmental) primes in masked priming can be accounted for in two ways. One is the sublexical pre-activation view according to which segments are pre-activated by the prime, and at the time the form-related target is to be produced, retrieval/assembly of those pre-activated segments is faster compared to an unrelated situation. However, it has also been argued that form-priming effects from sublexical primes might be due to lexical pre-activation. When the sublexical prime is presented, it activates all form-related words (i.e., cohorts) in the lexicon, necessarily including the form-related target, which—as a consequence—is produced faster than in the unrelated case. Note, however, that this lexical pre-activation account makes previous pre-lexical activation of segments necessary. This study reports a nonword naming experiment to investigate whether or not sublexical pre-activation is involved in masked form priming with sublexical primes. The results demonstrated a priming effect suggesting a nonlexical effect. However, this does not exclude an additional lexical component in form priming.
  • Hoymann, G. (2004). [Review of the book Botswana: The future of the minority languages ed. by Herman M. Batibo and Birgit Smieja]. Journal of African Languages and Linguistics, 25(2), 171-173. doi:10.1515/jall.2004.25.2.171.
  • Huettig, F., & Altmann, G. T. M. (2004). The online processing of ambiguous and unambiguous words in context: Evidence from head-mounted eye-tracking. In M. Carreiras, & C. Clifton (Eds.), The on-line study of sentence comprehension: Eyetracking, ERP and beyond (pp. 187-207). New York: Psychology Press.
  • Huettig, F. (2013). Young children’s use of color information during language-vision mapping. In B. R. Kar (Ed.), Cognition and brain development: Converging evidence from various methodologies (pp. 368-391). Washington, DC: American Psychological Association Press.
  • Indefrey, P., & Cutler, A. (2004). Prelexical and lexical processing in listening. In M. Gazzaniga (Ed.), The cognitive neurosciences III. (pp. 759-774). Cambridge, MA: MIT Press.

    Abstract

    This paper presents a meta-analysis of hemodynamic studies on passive auditory language processing. We assess the overlap of hemodynamic activation areas and activation maxima reported in experiments involving the presentation of sentences, words, pseudowords, or sublexical or non-linguistic auditory stimuli. Areas that have been reliably replicated are identified. The results of the meta-analysis are compared to electrophysiological, magnetencephalic (MEG), and clinical findings. It is concluded that auditory language input is processed in a left posterior frontal and bilateral temporal cortical network. Within this network, no processing leve l is related to a single cortical area. The temporal lobes seem to differ with respect to their involvement in post-lexical processing, in that the left temporal lobe has greater involvement than the right, and also in the degree of anatomical specialization for phonological, lexical, and sentence -level processing, with greater overlap on the right contrasting with a higher degree of differentiation on the left.
  • Indefrey, P., & Levelt, W. J. M. (2004). The spatial and temporal signatures of word production components. Cognition, 92(1-2), 101-144. doi:10.1016/j.cognition.2002.06.001.

    Abstract

    This paper presents the results of a comprehensive meta-analysis of the relevant imaging literature on word production (82 experiments). In addition to the spatial overlap of activated regions, we also analyzed the available data on the time course of activations. The analysis specified regions and time windows of activation for the core processes of word production: lexical selection, phonological code retrieval, syllabification, and phonetic/articulatory preparation. A comparison of the word production results with studies on auditory word/non-word perception and reading showed that the time course of activations in word production is, on the whole, compatible with the temporal constraints that perception processes impose on the production processes they affect in picture/word interference paradigms.
  • Indefrey, P., & Levelt, W. J. M. (1999). A meta-analysis of neuroimaging experiments on word production. Neuroimage, 7, 1028.
  • Indefrey, P. (1998). De neurale architectuur van taal: Welke hersengebieden zijn betrokken bij het spreken. Neuropraxis, 2(6), 230-237.
  • Indefrey, P. (2004). Hirnaktivierungen bei syntaktischer Sprachverarbeitung: Eine Meta-Analyse. In H. Müller, & G. Rickheit (Eds.), Neurokognition der Sprache (pp. 31-50). Tübingen: Stauffenburg.
  • Indefrey, P., Hellwig, F. M., Herzog, H., Seitz, R. J., & Hagoort, P. (2004). Neural responses to the production and comprehension of syntax in identical utterances. Brain and Language, 89(2), 312-319. doi:10.1016/S0093-934X(03)00352-3.

    Abstract

    Following up on an earlier positron emission tomography (PET) experiment (Indefrey et al., 2001), we used a scene description paradigm to investigate whether a posterior inferior frontal region subserving syntactic encoding for speaking is also involved in syntactic parsing during listening. In the language production part of the experiment, subjects described visually presented scenes
    using either sentences, sequences of noun phrases, or sequences of syntactically unrelated words. In the language comprehension part of the experiment, subjects were auditorily presented with the same kinds of utterances and judged whether they matched the visual scenes. We were able to replicate the previous finding of a region in caudal Broca s area that is sensitive to the complexity of
    syntactic encoding in language production. In language comprehension, no hemodynamic activation differences due to syntactic complexity were found. Given that correct performance in the judgment task did not require syntactic processing of the auditory stimuli, the results suggest that the degree to which listeners recruit syntactic processing resources in language comprehension may be a function of the syntactic demands of the task or the stimulus material.
  • Indefrey, P., Gruber, O., Brown, C. M., Hagoort, P., Posse, S., & Kleinschmidt, A. (1998). Lexicality and not syllable frequency determine lateralized premotor activation during the pronunciation of word-like stimuli: An fMRI study. NeuroImage, 7, S4.
  • Indefrey, P. (1999). Some problems with the lexical status of nondefault inflection. Behavioral and Brain Sciences, 22(6), 1025. doi:10.1017/S0140525X99342229.

    Abstract

    Clahsen's characterization of nondefault inflection as based exclusively on lexical entries does not capture the full range of empirical data on German inflection. In the verb system differential effects of lexical frequency seem to be input-related rather than affecting morphological production. In the noun system, the generalization properties of -n and -e plurals exceed mere analogy-based productivity.
  • Irvine, L., Roberts, S. G., & Kirby, S. (2013). A robustness approach to theory building: A case study of language evolution. In M. Knauff, M. Pauen, N. Sebanz, & I. Wachsmuth (Eds.), Proceedings of the 35th Annual Meeting of the Cognitive Science Society (CogSci 2013) (pp. 2614-2619). Retrieved from http://mindmodeling.org/cogsci2013/papers/0472/index.html.

    Abstract

    Models of cognitive processes often include simplifications, idealisations, and fictionalisations, so how should we learn about cognitive processes from such models? Particularly in cognitive science, when many features of the target system are unknown, it is not always clear which simplifications, idealisations, and so on, are appropriate for a research question, and which are highly misleading. Here we use a case-study from studies of language evolution, and ideas from philosophy of science, to illustrate a robustness approach to learning from models. Robust properties are those that arise across a range of models, simulations and experiments, and can be used to identify key causal structures in the models, and the phenomenon, under investigation. For example, in studies of language evolution, the emergence of compositional structure is a robust property across models, simulations and experiments of cultural transmission, but only under pressures for learnability and expressivity. This arguably illustrates the principles underlying real cases of language evolution. We provide an outline of the robustness approach, including its limitations, and suggest that this methodology can be productively used throughout cognitive science. Perhaps of most importance, it suggests that different modelling frameworks should be used as tools to identify the abstract properties of a system, rather than being definitive expressions of theories.
  • Ischebeck, A., Indefrey, P., Usui, N., Nose, I., Hellwig, F. M., & Taira, M. (2004). Reading in a regular orthography: An fMRI study investigating the role of visual familiarity. Journal of Cognitive Neuroscience, 16(5), 727-741. doi:10.1162/089892904970708.

    Abstract

    In order to separate the cognitive processes associated with phonological encoding and the use of a visual word form lexicon in reading, it is desirable to compare the processing of words presented in a visually familiar form with words in a visually unfamiliar form. Japanese Kana orthography offers this possibility. Two phonologically equivalent but visually dissimilar syllabaries allow the writing of, for example, foreign loanwords in two ways, only one of which is visually familiar. Familiarly written words, unfamiliarly written words, and pseudowords were presented in both Kana syllabaries (yielding six conditions in total) to participants during an fMRI measurement with a silent articulation task (Experiment 1) and a phonological lexical decision task (Experiment 2) using an event-related design. Consistent over two experimental tasks, the three different stimulus types (familiar, unfamiliar, and pseudoword) were found to activate selectively different brain regions previously associated with phonological encoding and word retrieval or meaning. Compatible with the predictions of the dual-route model for reading, pseudowords and visually unfamiliar words, which have to be read using phonological assembly, caused an increase in brain activity in left inferior frontal regions (BA 44/47), as compared to visually familiar words. Visually familiar and unfamiliar words were found to activate a range of areas associated with lexico-semantic processing more strongly than pseudowords, such as the left and right temporo-parietal region (BA 39/40), a region in the left middle/inferior temporal gyrus (BA 20/21), and the posterior cingulate (BA 31).
  • Janse, E., & Klitsch, J. (2004). Auditieve perceptie bij gezonde sprekers en bij sprekers met verworven taalstoornissen. Afasiologie, 26(1), 2-6.
  • Janse, E., & Newman, R. S. (2013). Identifying nonwords: Effects of lexical neighborhoods, phonotactic probability, and listener characteristics. Language and Speech, 56(4), 421-444. doi:10.1177/0023830912447914.

    Abstract

    Listeners find it relatively difficult to recognize words that are similar-sounding to other known words. In contrast, when asked to identify spoken nonwords, listeners perform better when the nonwords are similar to many words in their language. These effects of sound similarity have been assessed in multiple ways, and both sublexical (phonotactic probability) and lexical (neighborhood) effects have been reported, leading to models that incorporate multiple stages of processing. One prediction that can be derived from these models is that there may be differences among individuals in the size of these similarity effects as a function of working memory abilities. This study investigates how item-individual characteristics of nonwords (both phonotactic probability and neighborhood density) interact with listener-individual characteristics (such as cognitive abilities and hearing sensitivity) in the perceptual identification of nonwords. A set of nonwords was used in which neighborhood density and phonotactic probability were not correlated. In our data, neighborhood density affected identification more reliably than did phonotactic probability. The first study, with young adults, showed that higher neighborhood density particularly benefits nonword identification for those with poorer attention-switching control. This suggests that it may be easier to focus attention on a novel item if it activates and receives support from more similar-sounding neighbors. A similar study on nonword identification with older adults showed increased neighborhood density effects for those with poorer hearing, suggesting that activation of long-term linguistic knowledge is particularly important to back up auditory representations that are degraded as a result of hearing loss.
  • Janse, E., & Quené, H. (1999). On the suitability of the cross-modal semantic priming task. In Proceedings of the XIVth International Congress of Phonetic Sciences (pp. 1937-1940).
  • Janse, E. (2004). Word perception in fast speech: Artificially time-compressed vs. naturally produced fast speech. Speech Communication, 42, 155-173. doi:10.1016/j.specom.2003.07.001.

    Abstract

    Natural fast speech differs from normal-rate speech with respect to its temporal pattern. Previous results showed that word intelligibility of heavily artificially time-compressed speech could not be improved by making its temporal pattern more similar to that of natural fast speech. This might have been due to the extrapolation of timing rules for natural fast speech to rates that are much faster than can be attained by human speakers. The present study investigates whether, at a speech rate that human speakers can attain, artificially time-compressed speech is easier to process if its timing pattern is similar to that of naturally produced fast speech. Our first experiment suggests, however, that word processing speed was slowed down, relative to linear compression. In a second experiment, word processing of artificially time-compressed speech was compared with processing of naturally produced fast speech. Even when naturally produced fast speech is perfectly intelligible, its less careful articulation, combined with the changed timing pattern, slows down processing, relative to linearly time-compressed speech. Furthermore, listeners preferred artificially time-compressed speech over naturally produced fast speech. These results suggest that linearly time-compressed speech has both a temporal and a segmental advantage over natural fast speech.
  • Jansma, B. M., & Schiller, N. O. (2004). Monitoring syllable boundaries during speech production. Brain and Language, 90(1-3), 311-317. doi:10.1016/S0093-934X(03)00443-7.

    Abstract

    This study investigated the encoding of syllable boundary information during speech production in Dutch. Based on Levelt's model of phonological encoding, we hypothesized segments and syllable boundaries to be encoded in an incremental way. In a selfmonitoring experiment, decisions about the syllable affiliation (first or second syllable) of a pre-specified consonant, which was the third phoneme in a word, were required (e.g., ka.No canoe vs. kaN.sel pulpit ; capital letters indicate pivotal consonants, dots mark syllable boundaries). First syllable responses were faster than second syllable responses, indicating the incremental nature of segmental encoding and syllabification during speech production planning. The results of the experiment are discussed in the context of Levelt 's model of phonological encoding.
  • Janssen, D. P., Roelofs, A., & Levelt, W. J. M. (2004). Stem complexity and inflectional encoding in language production. Journal of Psycholinguistic Research, 33(5), 365-381. doi:10.1023/B:JOPR.0000039546.60121.a8.

    Abstract

    Three experiments are reported that examined whether stem complexity plays a role in inflecting polymorphemic words in language production. Experiment 1 showed that preparation effects for words with polymorphemic stems are larger when they are produced among words with constant inflectional structures compared to words with variable inflectional structures and simple stems. This replicates earlier findings for words with monomorphemic stems (Janssen et al., 2002). Experiments 2 and 3 showed that when inflectional structure is held constant, the preparation effects are equally large with simple and compound stems, and with compound and complex adjectival stems. These results indicate that inflectional encoding is blind to the complexity of the stem, which suggests that specific inflectional rather than generic morphological frames guide the generation of inflected forms in speaking words.
  • Janssen, D. (1999). Producing past and plural inflections. PhD Thesis, Radboud University Nijmegen, Nijmegen. doi:10.17617/2.2057667.
  • Janzen, G., & Van Turennout, M. (2004). Selective neural representation of objects relevant for navigation. Nature Neuroscience, 7(6), 673-677. doi:10.1038/nn1257.

    Abstract

    As people find their way through their environment, objects at navigationally relevant locations can serve as crucial landmarks. The parahippocampal gyrus has previously been shown to be involved in object and scene recognition. In the present study, we investigated the neural representation of navigationally relevant locations. Healthy human adults viewed a route through a virtual museum with objects placed at intersections (decision points) or at simple turns (non-decision points). Event-related functional magnetic resonance imaging (fMRI) data were acquired during subsequent recognition of the objects in isolation. Neural activity in the parahippocampal gyrus reflected the navigational relevance of an object's location in the museum. Parahippocampal responses were selectively increased for objects that occurred at decision points, independent of attentional demands. This increase occurred for forgotten as well as remembered objects, showing implicit retrieval of navigational information. The automatic storage of relevant object location in the parahippocampal gyrus provides a part of the neural mechanism underlying successful navigation.
  • Janzen, G., & Weststeijn, C. (2004). Neural representation of object location and route direction: An fMRI study. NeuroImage, 22(Supplement 1), e634-e635.
  • Janzen, G., & Van Turennout, M. (2004). Neuronale Markierung navigationsrelevanter Objekte im räumlichen Gedächtnis: Ein fMRT Experiment. In D. Kerzel (Ed.), Beiträge zur 46. Tagung experimentell arbeitender Psychologen (pp. 125-125). Lengerich: Pabst Science Publishers.
  • Jescheniak, J. D., & Levelt, W. J. M. (1994). Word frequency effects in speech production: Retrieval of syntactic information and of phonological form. Journal of Experimental Psychology: Learning, Memory, and Cognition, 20(4), 824-843.

    Abstract

    In 7 experiments the authors investigated the locus of word frequency effects in speech production. Experiment 1 demonstrated a frequency effect in picture naming that was robust over repetitions. Experiments 2, 3, and 7 excluded contributions from object identification and initiation of articulation. Experiments 4 and 5 investigated whether the effect arises in accessing the syntactic word (lemma) by using a grammatical gender decision task. Although a frequency effect was found, it dissipated under repeated access to word's gender. Experiment 6 tested whether the robust frequency effect arises in accessing the phonological form (lexeme) by having Ss translate words that produced homophones. Low-frequent homophones behaved like high-frequent controls, inheriting the accessing speed of their high-frequent homophone twins. Because homophones share the lexeme, not the lemma, this suggests a lexeme-level origin of the robust effect.
  • Johns, T. G., Perera, R. M., Vitali, A. A., Vernes, S. C., & Scott, A. (2004). Phosphorylation of a glioma-specific mutation of the EGFR [Abstract]. Neuro-Oncology, 6, 317.

    Abstract

    Mutations of the epidermal growth factor receptor (EGFR) gene are found at a relatively high frequency in glioma, with the most common being the de2-7 EGFR (or EGFRvIII). This mutation arises from an in-frame deletion of exons 2-7, which removes 267 amino acids from the extracellular domain of the receptor. Despite being unable to bind ligand, the de2-7 EGFR is constitutively active at a low level. Transfection of human glioma cells with the de2-7 EGFR has little effect in vitro, but when grown as tumor xenografts this mutated receptor imparts a dramatic growth advantage. We mapped the phosphorylation pattern of de2-7 EGFR, both in vivo and in vitro, using a panel of antibodies specific for different phosphorylated tyrosine residues. Phosphorylation of de2-7 EGFR was detected constitutively at all tyrosine sites surveyed in vitro and in vivo, including tyrosine 845, a known target in the wild-type EGFR for src kinase. There was a substantial upregulation of phosphorylation at every yrosine residue of the de2-7 EGFR when cells were grown in vivo compared to the receptor isolated from cells cultured in vitro. Upregulation of phosphorylation at tyrosine 845 could be stimulated in vitro by the addition of specific components of the ECM via an integrindependent mechanism. These observations may partially explain why the growth enhancement mediated by de2-7 EGFR is largely restricted to the in vivo environment
  • Johnson, E. K., Lahey, M., Ernestus, M., & Cutler, A. (2013). A multimodal corpus of speech to infant and adult listeners. Journal of the Acoustical Society of America, 134, EL534-EL540. doi:10.1121/1.4828977.

    Abstract

    An audio and video corpus of speech addressed to 28 11-month-olds is described. The corpus allows comparisons between adult speech directed towards infants, familiar adults and unfamiliar adult addressees, as well as of caregivers’ word teaching strategies across word classes. Summary data show that infant-directed speech differed more from speech to unfamiliar than familiar adults; that word teaching strategies for nominals versus verbs and adjectives differed; that mothers mostly addressed infants with multi-word utterances; and that infants’ vocabulary size was unrelated to speech rate, but correlated positively with predominance of continuous caregiver speech (not of isolated words) in the input.
  • De Jong, N. H., & Bosker, H. R. (2013). Choosing a threshold for silent pauses to measure second language fluency. In R. Eklund (Ed.), Proceedings of the 6th Workshop on Disfluency in Spontaneous Speech (DiSS) (pp. 17-20).

    Abstract

    Second language (L2) research often involves analyses of acoustic measures of fluency. The studies investigating fluency, however, have been difficult to compare because the measures of fluency that were used differed widely. One of the differences between studies concerns the lower cut-off point for silent pauses, which has been set anywhere between 100 ms and 1000 ms. The goal of this paper is to find an optimal cut-off point. We calculate acoustic measures of fluency using different pause thresholds and then relate these measures to a measure of L2 proficiency and to ratings on fluency.
  • Jordan, F. M., van Schaik, C. P., Francois, P., Gintis, H., Haun, D. B. M., Hruschka, D. H., Janssen, M. A., Kitts, J. A., Lehmann, L., Mathew, S., Richerson, P. J., Turchin, P., & Wiessner, P. (2013). Cultural evolution of the structure of human groups. In P. J. Richerson, & M. H. Christiansen (Eds.), Cultural Evolution: Society, technology, language, and religion (pp. 87-116). Cambridge, MA: MIT Press.
  • Jordan, F. (2013). Comparative phylogenetic methods and the study of pattern and process in kinship. In P. McConvell, I. Keen, & R. Hendery (Eds.), Kinship systems: Change and reconstruction (pp. 43-58). Salt Lake City, UT: University of Utah Press.

    Abstract

    Anthropology began by comparing aspects of kinship across cultures, while linguists interested in semantic domains such as kinship necessarily compare across languages. In this chapter I show how phylogenetic comparative methods from evolutionary biology can be used to study evolutionary processes relating to kinship and kinship terminologies across language and culture.
  • Jordan, F., & Huber, B. H. (2013). Introduction: Evolutionary processes in language and culture group. Cross-Cultural Research, 47(2), 91 -101. doi:10.1177/1069397112471800.

    Abstract

    This special issue “Evolutionary Approaches to Cross-Cultural Anthropology” brings together scholars from the fields of behavioral ecology, evolutionary psychology, and cultural evolution whose cross-cultural work draws on evolutionary theory and methods. The papers here are a subset of those presented at a symposium we organized for the 2011 meeting of the Society for Cross-Cultural Research held in Charleston, South Carolina. Collectively, our authors show how an engagement with cultural variation has enriched evolutionary anthropology, and these papers showcase how cross-cultural research can benefit from the theoretical and methodological contributions of an evolutionary approach.
  • Jordens, P. (2004). Systematiek en dynamiek bij de verwerving van Finietheid. Toegepaste Taalwetenschap in Artikelen, 71, 9-22.

    Abstract

    In early Dutch learner varieties, there is no evidence of finiteness being a functional category. There is no V2nd: no correlation between inflectional morphology and movement. Initially, learners express the illocutive function of finiteness through the use of illocutive markers, with the non-use of an illocutive marker expressing the default illocutive function of assertion. Illocutive markers are functioning as adjuncts with scope over the predicate. Illocutive markers become re-analysed as functional elements.The driving force is the acquisition of the auxiliary verbs that occur with past participles. It leads to a reanalysis of illocutive markers as two separate elements: an auxiliary verb and a scope adverb. The (modal) auxiliary carries illocutive function. Lexical verb-argument structure (including the external argument) occurs within the domain of the auxiliary verb. The predicate as the focus constituent occurs within the domain of a scope adverb. This reanalysis establishes a position for the external argument within the domain of AUX. The acquisition of AUX causes the acquisition of a (hierarchical) structure with a complement as a constituent which represents an underlying verb-argument structure, a predicate as the domain of elements that are in focus, and an external (specifier) position as a landing site for elements with topic function.
  • Jordens, P. (1998). Defaultformen des Präteritums. Zum Erwerb der Vergangenheitsmorphologie im Niederlänidischen. In H. Wegener (Ed.), Eine zweite Sprache lernen (pp. 61-88). Tübingen, Germany: Verlag Gunter Narr.
  • Jordens, P. (2013). Dummies and auxiliaries in the acquisition of L1 and L2 Dutch. In E. Blom, I. Van de Craats, & J. Verhagen (Eds.), Dummy Auxiliaries in First and Second Language Acquisition (pp. 341-368). Berlin: Mouton de Gruyter.
  • Jordens, P. (2004). Morphology in Second Language Acquisition. In G. Booij (Ed.), Morphologie: Ein internationales Handbuch zur Flexion und Wortbildung (pp. 1806-1816). Berlin: Walter de Gruyter.
  • Julvez, J., Smith, G. D., Golding, J., Ring, S., St Pourcain, B., Gonzalez, J. R., & Grandjean, P. (2013). Prenatal methylmercury exposure and genetic predisposition to cognitive deficit at age 8 years. Epidemiology, 24(5), 643-650. doi:10.1097/EDE.0b013e31829d5c93.

    Abstract

    BACKGROUND: Cognitive consequences at school age associated with prenatal methylmercury (MeHg) exposure may need to take into account nutritional and sociodemographic cofactors as well as relevant genetic polymorphisms. METHODS: A subsample (n = 1,311) of the Avon Longitudinal Study of Parents and Children (Bristol, UK) was selected, and mercury (Hg) concentrations were measured in freeze-dried umbilical cord tissue as a measure of MeHg exposure. A total of 1135 children had available data on 247 single-nucleotide polymorphisms (SNPs) within relevant genes, as well as the Wechsler Intelligence Scale for Children Intelligence Quotient (IQ) scores at age 8 years. Multivariate regression models were used to assess the associations between MeHg exposure and IQ and to determine possible gene-environment interactions. RESULTS: Hg concentrations indicated low background exposures (mean = 26 ng/g, standard deviation = 13). Log10-transformed Hg was positively associated with IQ, which attenuated after adjustment for nutritional and sociodemographic cofactors. In stratified analyses, a reverse association was found in higher social class families (for performance IQ, P value for interaction = 0.0013) among whom there was a wider range of MeHg exposure. Among 40 SNPs showing nominally significant main effects, MeHg interactions were detected for rs662 (paraoxonase 1) and rs1042838 (progesterone receptor) (P <} 0.05) and for rs3811647 (transferrin) and rs2049046 (brain-derived neurotrophic factor) (P {< 0.10). CONCLUSIONS: In this population with a low level of MeHg exposure, there were only equivocal associations between MeHg exposure and adverse neuropsychological outcomes. Heterogeneities in several relevant genes suggest possible genetic predisposition to MeHg neurotoxicity in a substantial proportion of the population. Future studies need to address this possibility.
  • Kajihara, T., Verdonschot, R. G., Sparks, J., & Stewart, L. (2013). Action-perception coupling in violinists. Frontiers in Human Neuroscience, 7: 349. doi:10.3389/fnhum.2013.00349.

    Abstract

    The current study investigates auditory-motor coupling in musically trained participants using a Stroop-type task that required the execution of simple finger sequences according to aurally presented number sequences (e.g., "2," " 4," "5," "3," "1"). Digital remastering was used to manipulate the pitch contour of the number sequences such that they were either congruent or incongruent with respect to the resulting action sequence. Conservatoire-level violinists showed a strong effect of congruency manipulation (increased response time for incongruent vs. congruent trials), in comparison to a control group of non-musicians. In Experiment 2, this paradigm was used to determine whether pedagogical background would influence this effect in a group of young violinists. Suzuki-trained violinists differed significantly from those with no musical background, while traditionally-trained violinists did not. The findings extend previous research in this area by demonstrating that obligatory audio-motor coupling is directly related to a musicians' expertise on their instrument of study and is influenced by pedagogy.
  • Kallmeyer, L., Osswald, R., & Van Valin Jr., R. D. (2013). Tree wrapping for Role and Reference Grammar. In G. Morrill, & M.-J. Nederhof (Eds.), Formal grammar: 17th and 18th International Conferences, FG 2012/2013, Opole, Poland, August 2012: revised Selected Papers, Düsseldorf, Germany, August 2013: proceedings (pp. 175-190). Heidelberg: Springer.
  • Kaltwasser, L., Ries, S., Sommer, W., Knight, R., & Willems, R. M. (2013). Independence of valence and reward in emotional word processing: Electrophysiological evidence. Frontiers in Psychology, 4: 168. doi:10.3389/fpsyg.2013.00168.

    Abstract

    Both emotion and reward are primary modulators of cognition: Emotional word content enhances word processing, and reward expectancy similarly amplifies cognitive processing from the perceptual up to the executive control level. Here, we investigate how these primary regulators of cognition interact. We studied how the anticipation of gain or loss modulates the neural time course (event-related potentials, ERPs) related to processing of emotional words. Participants performed a semantic categorization task on emotional and neutral words, which were preceded by a cue indicating that performance could lead to monetary gain or loss. Emotion-related and reward-related effects occurred in different time windows, did not interact statistically, and showed different topographies. This speaks for an independence of reward expectancy and the processing of emotional word content. Therefore, privileged processing given to emotionally valenced words seems immune to short-term modulation of reward. Models of language comprehension should be able to incorporate effects of reward and emotion on language processing, and the current study argues for an architecture in which reward and emotion do not share a common neurobiological mechanism
  • Kempen, G. (2004). Terug naar Wundt: Pleidooi voor integraal onderzoek van taal, taalkennis en taalgedrag. In Koninklijke Nederlandse Akademie van Wetenschappen (Ed.), Gij letterdames en gij letterheren': Nieuwe mogelijkheden voor taalkundig en letterkundig onderzoek in Nederland. (pp. 174-188). Amsterdam: Koninklijke Nederlandse Akademie van Wetenschappen.
  • Kempen, G. (1994). De mythe van het woordbeeld: Spellingherziening taalpsychologisch doorgelicht. Spektator, tijdschrift voor Neerlandistiek, 23, 292-301.
  • Kempen, G. (1998). Comparing and explaining the trajectories of first and second language acquisition: In search of the right mix of psychological and linguistic factors [Commentory]. Bilingualism: Language and Cognition, 1, 29-30. doi:10.1017/S1366728998000066.

    Abstract

    When you compare the behavior of two different age groups which are trying to master the same sensori-motor or cognitive skill, you are likely to discover varying learning routes: different stages, different intervals between stages, or even different orderings of stages. Such heterogeneous learning trajectories may be caused by at least six different types of factors: (1) Initial state: the kinds and levels of skills the learners have available at the onset of the learning episode. (2) Learning mechanisms: rule-based, inductive, connectionist, parameter setting, and so on. (3) Input and feedback characteristics: learning stimuli, information about success and failure. (4) Information processing mechanisms: capacity limitations, attentional biases, response preferences. (5) Energetic variables: motivation, emotional reactions. (6) Final state: the fine-structure of kinds and levels of subskills at the end of the learning episode. This applies to language acquisition as well. First and second language learners probably differ on all six factors. Nevertheless, the debate between advocates and opponents of the Fundamental Difference Hypothesis concerning L1 and L2 acquisition have looked almost exclusively at the first two factors. Those who believe that L1 learners have access to Universal Grammar whereas L2 learners rely on language processing strategies, postulate different learning mechanisms (UG parameter setting in L1, more general inductive strategies in L2 learning). Pienemann opposes this view and, based on his Processability Theory, argues that L1 and L2 learners start out from different initial states: they come to the grammar learning task with different structural hypotheses (SOV versus SVO as basic word order of German).
  • Kempen, G., Schotel, H., & Hoenkamp, E. (1982). Analyse-door-synthese van Nederlandse zinnen [Abstract]. De Psycholoog, 17, 509.
  • Kempen, G. (1973). [Review of the book Psycholinguïstiek by B. Tervoort et al.]. Nederlands Tijdschrift voor de Psychologie, 28, 172-174.
  • Kempen, G., & Harbusch, K. (1998). A 'tree adjoining' grammar without adjoining: The case of scrambling in German. In Fourth International Workshop on Tree Adjoining Grammars and Related Frameworks (TAG+4).
  • Kempen, G., & Harbusch, K. (2004). A corpus study into word order variation in German subordinate clauses: Animacy affects linearization independently of grammatical function assignment. In T. Pechmann, & C. Habel (Eds.), Multidisciplinary approaches to language production (pp. 173-181). Berlin: Mouton de Gruyter.
  • Kempen, G., & Harbusch, K. (2004). Generating natural word orders in a semi-free word order language: Treebank-based linearization preferences for German. In A. Gelbukh (Ed.), Computational Linguistics and Intelligent Text Processing (pp. 350-354). Berlin: Springer.

    Abstract

    We outline an algorithm capable of generating varied but natural sounding sequences of argument NPs in subordinate clauses of German, a semi-free word order language. In order to attain the right level of output flexibility, the algorithm considers (1) the relevant lexical properties of the head verb (not only transitivity type but also reflexivity, thematic relations expressed by the NPs, etc.), and (2) the animacy and definiteness values of the arguments, and their length. The relevant statistical data were extracted from the NEGRA–II treebank and from hand-coded features for animacy and definiteness. The algorithm maps the relevant properties onto “primary” versus “secondary” placement options in the generator. The algorithm is restricted in that it does not take into account linear order determinants related to the sentence’s information structure and its discourse context (e.g. contrastiveness). These factors may modulate the above preferences or license “tertiary” linear orders beyond the primary and secondary options considered here.
  • Kempen, G., & Harbusch, K. (2004). How flexible is constituent order in the midfield of German subordinate clauses? A corpus study revealing unexpected rigidity. In S. Kepser, & M. Reis (Eds.), Pre-Proceedings of the International Conference on Linguistic Evidence (pp. 81-85). Tübingen: Niemeyer.
  • Kempen, G. (2004). Interactive visualization of syntactic structure assembly for grammar-intensive first- and second-language instruction. In R. Delmonte, P. Delcloque, & S. Tonelli (Eds.), Proceedings of InSTIL/ICALL2004 Symposium on NLP and speech technologies in advanced language learning systems (pp. 183-186). Venice: University of Venice.

Share this page