Publications

Displaying 501 - 575 of 575
  • Smalley, S. L., Kustanovich, V., Minassian, S. L., Stone, J. L., Ogdie, M. N., McGough, J. J., McCracken, J. T., MacPhie, I. L., Francks, C., Fisher, S. E., Cantor, R. M., Monaco, A. P., & Nelson, S. F. (2002). Genetic linkage of Attention-Deficit/Hyperactivity Disorder on chromosome 16p13, in a region implicated in autism. American Journal of Human Genetics, 71(4), 959-963. doi:10.1086/342732.

    Abstract

    Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in childhood and likely represents an extreme of normal behavior. ADHD significantly impacts learning in school-age children and leads to impaired functioning throughout the life span. There is strong evidence for a genetic etiology of the disorder, although putative alleles, principally in dopamine-related pathways suggested by candidate-gene studies, have very small effect sizes. We use affected-sib-pair analysis in 203 families to localize the first major susceptibility locus for ADHD to a 12-cM region on chromosome 16p13 (maximum LOD score 4.2; P=.000005), building upon an earlier genomewide scan of this disorder. The region overlaps that highlighted in three genome scans for autism, a disorder in which inattention and hyperactivity are common, and physically maps to a 7-Mb region on 16p13. These findings suggest that variations in a gene on 16p13 may contribute to common deficits found in both ADHD and autism.
  • De Smedt, K., & Kempen, G. (1991). Segment Grammar: A formalism for incremental sentence generation. In C. Paris, W. Swartout, & W. Mann (Eds.), Natural language generation and computational linguistics (pp. 329-349). Dordrecht: Kluwer Academic Publishers.

    Abstract

    Incremental sentence generation imposes special constraints on the representation of the grammar and the design of the formulator (the module which is responsible for constructing the syntactic and morphological structure). In the model of natural speech production presented here, a formalism called Segment Grammar is used for the representation of linguistic knowledge. We give a definition of this formalism and present a formulator design which relies on it. Next, we present an object- oriented implementation of Segment Grammar. Finally, we compare Segment Grammar with other formalisms.
  • Spinelli, E., Cutler, A., & McQueen, J. M. (2002). Resolution of liaison for lexical access in French. Revue Française de Linguistique Appliquée, 7, 83-96.

    Abstract

    Spoken word recognition involves automatic activation of lexical candidates compatible with the perceived input. In running speech, words abut one another without intervening gaps, and syllable boundaries can mismatch with word boundaries. For instance, liaison in ’petit agneau’ creates a syllable beginning with a consonant although ’agneau’ begins with a vowel. In two cross-modal priming experiments we investigate how French listeners recognise words in liaison environments. These results suggest that the resolution of liaison in part depends on acoustic cues which distinguish liaison from non-liaison consonants, and in part on the availability of lexical support for a liaison interpretation.
  • Sprenger, S. A., & Van Rijn, H. (2005). Clock time naming: Complexities of a simple task. In B. G. Bara, L. Barsalou, & M. Bucciarelli (Eds.), Proceedings of the 27th Annual Meeting of the Cognitive Science Society (pp. 2062-2067).
  • Srivastava, S., Budwig, N., & Narasimhan, B. (2005). A developmental-functionalist view of the development of transitive and intratransitive constructions in a Hindi-speaking child: A case study. International Journal of Idiographic Science, 2.
  • Stivers, T. (2005). Parent resistance to physicians' treatment recommendations: One resource for initiating a negotiation of the treatment decision. Health Communication, 18(1), 41-74. doi:10.1207/s15327027hc1801_3.

    Abstract

    This article examines pediatrician-parent interaction in the context of acute pediatric encounters for children with upper respiratory infections. Parents and physicians orient to treatment recommendations as normatively requiring parent acceptance for physicians to close the activity. Through acceptance, withholding of acceptance, or active resistance, parents have resources with which to negotiate for a treatment outcome that is in line with their own wants. This article offers evidence that even in acute care, shared decision making not only occurs but, through normative constraints, is mandated for parents and physicians to reach accord in the treatment decision.
  • Stivers, T. (2005). Modified repeats: One method for asserting primary rights from second position. Research on Language and Social Interaction, 38(2), 131-158. doi:10.1207/s15327973rlsi3802_1.

    Abstract

    In this article I examine one practice speakers have for confirming when confirmation was not otherwise relevant. The practice involves a speaker repeating an assertion previously made by another speaker in modified form with stress on the copula/auxiliary. I argue that these modified repeats work to undermine the first speaker's default ownership and rights over the claim and instead assert the primacy of the second speaker's rights to make the statement. Two types of modified repeats are identified: partial and full. Although both involve competing for primacy of the claim, they occur in distinct sequential environments: The former are generally positioned after a first claim was epistemically downgraded, whereas the latter are positioned following initial claims that were offered straightforwardly, without downgrading.
  • Stivers, T. (2002). 'Symptoms only' and 'Candidate diagnoses': Presenting the problem in pediatric encounters. Health Communication, 14(3), 299-338.
  • Stivers, T., & Sidnell, J. (2005). Introduction: Multimodal interaction. Semiotica, 156(1/4), 1-20. doi:10.1515/semi.2005.2005.156.1.

    Abstract

    That human social interaction involves the intertwined cooperation of different modalities is uncontroversial. Researchers in several allied fields have, however, only recently begun to document the precise ways in which talk, gesture, gaze, and aspects of the material surround are brought together to form coherent courses of action. The papers in this volume are attempts to develop this line of inquiry. Although the authors draw on a range of analytic, theoretical, and methodological traditions (conversation analysis, ethnography, distributed cognition, and workplace studies), all are concerned to explore and illuminate the inherently multimodal character of social interaction. Recent studies, including those collected in this volume, suggest that different modalities work together not only to elaborate the semantic content of talk but also to constitute coherent courses of action. In this introduction we present evidence for this position. We begin by reviewing some select literature focusing primarily on communicative functions and interactive organizations of specific modalities before turning to consider the integration of distinct modalities in interaction.
  • Stivers, T. (2005). Non-antibiotic treatment recommendations: Delivery formats and implications for parent resistance. Social Science & Medicine, 60(5), 949-964. doi:10.1016/j.socscimed.2004.06.040.

    Abstract

    This study draws on a database of 570 community-based acute pediatric encounters in the USA and uses conversation analysis as a methodology to identify two formats physicians use to recommend non-antibiotic treatment in acute pediatric care (using a subset of 309 cases): recommendations for particular treatment (e.g., “I’m gonna give her some cough medicine.”) and recommendations against particular treatment (e.g., “She doesn’t need any antibiotics.”). The findings are that the presentation of a specific affirmative recommendation for treatment is less likely to engender parent resistance to a non-antibiotic treatment recommendation than a recommendation against particular treatment even if the physician later offers a recommendation for particular treatment. It is suggested that physicians who provide a specific positive treatment recommendation followed by a negative recommendation are most likely to attain parent alignment and acceptance when recommending a non-antibiotic treatment for a viral upper respiratory illness.
  • Stivers, T. (2002). Overt parent pressure for antibiotic medication in pediatric encounters. Social Science and Medicine, 54(7), 1111-1130.
  • Striano, T., & Liszkowski, U. (2005). Sensitivity to the context of facial expression in the still face at 3-, 6-, and 9-months of age. Infant Behavior and Development, 28(1), 10-19. doi:10.1016/j.infbeh.2004.06.004.

    Abstract

    Thirty-eight 3-, 6-, and 9-month-old infants interacted in a face to face situation with a female stranger who disrupted the on-going interaction with 30 s Happy and Neutral still face episodes. Three- and 6-month-olds manifested a robust still face response for gazing and smiling. For smiling, 9-month-olds manifested a floor effect such that no still face effect could be shown. For gazing, 9-month-olds' still face response was modulated by the context of interaction such that it was less pronounced if a happy still face was presented first. The findings point to a developmental transition by the end of the first year, whereby infants' still face response becomes increasingly influenced by the context of social interaction. (C) 2004 Published by Elsevier Inc. [References: 35]
  • Swingley, D., & Fernald, A. (2002). Recognition of words referring to present and absent objects by 24-month-olds. Journal of Memory and Language, 46(1), 39-56. doi:10.1006/jmla.2001.2799.

    Abstract

    Three experiments tested young children's efficiency in recognizing words in speech referring to absent objects. Seventy-two 24-month-olds heard sentences containing target words denoting objects that were or were not present in a visual display. Children's eye movements were monitored as they heard the sentences. Three distinct patterns of response were shown. Children hearing a familiar word that was an appropriate label for the currently fixated picture maintained their gaze. Children hearing a familiar word that could not apply to the currently fixated picture rapidly shifted their gaze to the alternative picture, whether that alternative was the named target or not, and then continued to search for an appropriate referent. Finally, children hearing an unfamiliar word shifted their gaze slowly and irregularly. This set of outcomes is interpreted as evidence that by 24 months, rapid activation in word recognition does not depend on the presence of the words' referents. Rather, very young children are capable of quickly and efficiently interpreting words in the absence of visual supporting context.
  • Swingley, D. (2005). Statistical clustering and the contents of the infant vocabulary. Cognitive Psychology, 50(1), 86-132. doi:10.1016/j.cogpsych.2004.06.001.

    Abstract

    Infants parse speech into word-sized units according to biases that develop in the first year. One bias, present before the age of 7 months, is to cluster syllables that tend to co-occur. The present computational research demonstrates that this statistical clustering bias could lead to the extraction of speech sequences that are actual words, rather than missegmentations. In English and Dutch, these word-forms exhibit the strong–weak (trochaic) pattern that guides lexical segmentation after 8 months, suggesting that the trochaic parsing bias is learned as a generalization from statistically extracted bisyllables, and not via attention to short utterances or to high-frequency bisyllables. Extracted word-forms come from various syntactic classes, and exhibit distributional characteristics enabling rudimentary sorting of words into syntactic categories. The results highlight the importance of infants’ first year in language learning: though they may know the meanings of very few words, infants are well on their way to building a vocabulary.
  • Swingley, D. (2005). 11-month-olds' knowledge of how familiar words sounds. Developmental Science, 8(5), 432-443. doi:10.1111/j.1467-7687.2005.00432.

    Abstract

    During the first year of life, infants' perception of speech becomes tuned to the phonology of the native language, as revealed in laboratory discrimination and categorization tasks using syllable stimuli. However, the implications of these results for the development of the early vocabulary remain controversial, with some results suggesting that infants retain only vague, sketchy phonological representations of words. Five experiments using a preferential listening procedure tested Dutch 11-month-olds' responses to word, nonword and mispronounced-word stimuli. Infants listened longer to words than nonwords, but did not exhibit this response when words were mispronounced at onset or at offset. In addition, infants preferred correct pronunciations to onset mispronunciations. The results suggest that infants' encoding of familiar words includes substantial phonological detail.
  • Swingley, D., & Aslin, R. N. (2002). Lexical neighborhoods and the word-form representations of 14-month-olds. Psychological Science, 13(5), 480-484. doi:10.1111/1467-9280.00485.

    Abstract

    The degree to which infants represent phonetic detail in words has been a source of controversy in phonology and developmental psychology. One prominent hypothesis holds that infants store words in a vague or inaccurate form until the learning of similar–sounding neighbors forces attention to subtle phonetic distinctions. In the experiment reported here, we used a visual fixation task to assess word recognition. We present the first evidence indicating that, in fact, the lexical representations of 14– and 15–month–olds are encoded in fine detail, even when this detail is not functionally necessary for distinguishing similar words in the infant’s vocabulary. Exposure to words is sufficient for well–specified lexical representations, even well before the vocabulary spurt. These results suggest developmental continuity in infants’ representations of speech: As infants begin to build a vocabulary and learn word meanings, they use the perceptual abilities previously demonstrated in tasks testing the discrimination and categorization of meaningless syllables.
  • ten Bosch, L., & Scharenborg, O. (2005). ASR decoding in a computational model of human word recognition. In Interspeech'2005 - Eurospeech, 9th European Conference on Speech Communication and Technology (pp. 1241-1244). ISCA Archive.

    Abstract

    This paper investigates the interaction between acoustic scores and symbolic mismatch penalties in multi-pass speech decoding techniques that are based on the creation of a segment graph followed by a lexical search. The interaction between acoustic and symbolic mismatches determines to a large extent the structure of the search space of these multipass approaches. The background of this study is a recently developed computational model of human word recognition, called SpeM. SpeM is able to simulate human word recognition data and is built as a multi-pass speech decoder. Here, we focus on unravelling the structure of the search space that is used in SpeM and similar decoding strategies. Finally, we elaborate on the close relation between distances in this search space, and distance measures in search spaces that are based on a combination of acoustic and phonetic features.
  • Ter Keurs, M., Brown, C. M., & Hagoort, P. (2002). Lexical processing of vocabulary class in patients with Broca's aphasia: An event-related brain potential study on agrammatic comprehension. Neuropsychologia, 40(9), 1547-1561. doi:10.1016/S0028-3932(02)00025-8.

    Abstract

    This paper presents electrophysiological evidence of an impairment in the on-line processing of word class information in patients with Broca’s aphasia with agrammatic comprehension. Event-related brain potentials (ERPs) were recorded from the scalp while Broca patients and non-aphasic control subjects read open- and closed-class words that appeared one at a time on a PC screen. Separate waveforms were computed for open- and closed-class words. The non-aphasic control subjects showed a modulation of an early left anterior negativity in the 210–325 ms as a function of vocabulary class (VC), and a late left anterior negative shift to closed-class words in the 400–700 ms epoch. An N400 effect was present in both control subjects and Broca patients. We have taken the early electrophysiological differences to reflect the first availability of word-category information from the mental lexicon. The late differences can be related to post-lexical processing. In contrast to the control subjects, the Broca patients showed no early VC effect and no late anterior shift to closed-class words. The results support the view that an incomplete and/or delayed availability of word-class information might be an important factor in Broca’s agrammatic comprehension.
  • Terrill, A. (2002). Systems of nominal classification in East Papuan languages. Oceanic Linguistics, 41(1), 63-88.

    Abstract

    The existence of nominal classification systems has long been thought of as one of the defining features of the Papuan languages of island New Guinea. However, while almost all of these languages do have nominal classification systems, they are, in fact, extremely divergent from each other. This paper examines these systems in the East Papuan languages in order to examine the question of the relationship between these Papuan outliers. Nominal classification systems are often archaic, preserving older features lost elsewhere in a language. Also, evidence shows that they are not easily borrowed into languages (although they can be). For these reasons, it is useful to consider nominal classification systems as a tool for exploring ancient historical relationships between languages. This paper finds little evidence of relationship between the nominal classification systems of the East Papuan languages as a whole. It argues that the mere existence of nominal classification systems cannot be used as evidence that the East Papuan languages form a genetic family. The simplest hypothesis is that either the systems were inherited so long ago as to obscure the genetic evidence, or else the appearance of nominal classification systems in these languages arose through borrowing of grammatical systems rather than of morphological forms.
  • Terrill, A. (2002). Why make books for people who can't read? A perspective on documentation of an endangered language from Solomon Islands. International Journal of the Sociology of Language, 155/156(1), 205-219. doi:10.1515/ijsl.2002.029.

    Abstract

    This paper explores the issue of documenting an endangered language from the perspective of a community with low levels of literacy, I first discuss the background of the language community with whom I work, the Lavukal people of Solomon Islands, and discuss whether, and to what extent, Lavukaleve is an endangered language. I then go on to discuss the documentation project. My main point is that while low literacy levels and a nonreading culture would seem to make documentation a strange choice as a tool for language maintenance, in fact both serve as powerful cultural symbols of the importance and prestige of Lavukaleve. It is well known that a common reason for language death is that speakers choose not to transmit their language to the next generation (e.g. Winter 1993). Lavukaleve is particularly vulnerable in this respect. By utilizing cultural symbols of status and prestige, the standing of Lavukaleve can be enhanced, thus helping to ensure the transmission of Lavukaleve to future generations.
  • Terrill, A. (2002). [Review of the book The Interface between syntax and discourse in Korafe, a Papuan language of Papua New Guinea by Cynthia J. M. Farr]. Linguistic Typology, 6(1), 110-116. doi:10.1515/lity.2002.004.
  • Terrill, A. (2002). Dharumbal: The language of Rockhampton, Australia. Canberra: Pacific Linguistics.
  • Terrill, A. (2002). [Review of the book The Interface between syntax and discourse in Korafe, a Papuan language of Papua New Guinea by Cynthia J. M. Farr]. Linguistic Typology, 6(1), 110-116. doi:10.1515/lity.2002.004.
  • Theakston, A. L., Lieven, E. V., Pine, J. M., & Rowland, C. F. (2002). Going, going, gone: The acquisition of the verb ‘go’. Journal of Child Language, 29(4), 783-811. doi:10.1017/S030500090200538X.

    Abstract

    This study investigated different accounts of early argument structure acquisition and verb paradigm building through the detailed examination of the acquisition of the verb Go. Data from 11 children followed longitudinally between the ages of 2;0 and 3;0 were examined. Children's uses of the different forms of Go were compared with respect to syntactic structure and the semantics encoded. The data are compatible with the suggestion that the children were not operating with a single verb representation that differentiated between different forms of Go but rather that their knowledge of the relationship between the different forms of Go varied depending on the structure produced and the meaning encoded. However, a good predictor of the children's use of different forms of Go in particular structures and to express particular meanings was the frequency of use of those structures and meanings with particular forms of Go in the input. The implications of these findings for theories of syntactic category formation and abstract rule-based descriptions of grammar are discussed.
  • Theakston, A. L., Lieven, E. V., Pine, J. M., & Rowland, C. F. (2005). The acquisition of auxiliary syntax: BE and HAVE. Cognitive Linguistics, 16(1), 247-277. doi:10.1515/cogl.2005.16.1.247.

    Abstract

    This study examined patterns of auxiliary provision and omission for the auxiliaries BE and HAVE in a longitudinal data set from 11 children between the ages of two and three years. Four possible explanations for auxiliary omission—a lack of lexical knowledge, performance limitations in production, the Optional Infinitive hypothesis, and patterns of auxiliary use in the input—were examined. The data suggest that although none of these accounts provides a full explanation for the pattern of auxiliary use and nonuse observed in children's early speech, integrating input-based and lexical learning-based accounts of early language acquisition within a constructivist approach appears to provide a possible framework in which to understand the patterns of auxiliary use found in the children's speech. The implications of these findings for models of children's early language acquisition are discussed.
  • Trilsbeek, P., & Wittenburg, P. (2005). Archiving challenges. In J. Gippert, N. Himmelmann, & U. Mosel (Eds.), Essentials of language documentation (pp. 311-335). Berlin: Mouton de Gruyter.
  • Troncarelli, M. C., & Drude, S. (2002). Awytyza Ti'ingku. Livro para alfabetização na língua aweti: Awytyza Ti’ingku. Alphabetisierungs‐Fibel der Awetí‐Sprache. São Paulo: Instituto Sócio-Ambiental.
  • Van de Geer, J. P., & Levelt, W. J. M. (1963). Detection of visual patterns disturbed by noise: An exploratory study. Quarterly Journal of Experimental Psychology, 15, 192-204. doi:10.1080/17470216308416324.

    Abstract

    An introductory study of the perception of stochastically specified events is reported. The initial problem was to determine whether the perceiver can split visual input data of this kind into random and determined components. The inability of subjects to do so with the stimulus material used (a filmlike sequence of dot patterns), led to the more general question of how subjects code this kind of visual material. To meet the difficulty of defining the subjects' responses, two experiments were designed. In both, patterns were presented as a rapid sequence of dots on a screen. The patterns were more or less disturbed by “noise,” i.e. the dots did not appear exactly at their proper places. In the first experiment the response was a rating on a semantic scale, in the second an identification from among a set of alternative patterns. The results of these experiments give some insight in the coding systems adopted by the subjects. First, noise appears to be detrimental to pattern recognition, especially to patterns with little spread. Second, this shows connections with the factors obtained from analysis of the semantic ratings, e.g. easily disturbed patterns show a large drop in the semantic regularity factor, when only a little noise is added.
  • Van Ooijen, B., Cutler, A., & Norris, D. (1991). Detection times for vowels versus consonants. In Eurospeech 91: Vol. 3 (pp. 1451-1454). Genova: Istituto Internazionale delle Comunicazioni.

    Abstract

    This paper reports two experiments with vowels and consonants as phoneme detection targets in real words. In the first experiment, two relatively distinct vowels were compared with two confusible stop consonants. Response times to the vowels were longer than to the consonants. Response times correlated negatively with target phoneme length. In the second, two relatively distinct vowels were compared with their corresponding semivowels. This time, the vowels were detected faster than the semivowels. We conclude that response time differences between vowels and stop consonants in this task may reflect differences between phoneme categories in the variability of tokens, both in the acoustic realisation of targets and in the' representation of targets by subjects.
  • Van Berkum, J. J. A., Hijne, H., De Jong, T., Van Joolingen, W. R., & Njoo, M. (1991). Aspects of computer simulations in education. Education & Computing, 6(3/4), 231-239.

    Abstract

    Computer simulations in an instructional context can be characterized according to four aspects (themes): simulation models, learning goals, learning processes and learner activity. The present paper provides an outline of these four themes. The main classification criterion for simulation models is quantitative vs. qualitative models. For quantitative models a further subdivision can be made by classifying the independent and dependent variables as continuous or discrete. A second criterion is whether one of the independent variables is time, thus distinguishing dynamic and static models. Qualitative models on the other hand use propositions about non-quantitative properties of a system or they describe quantitative aspects in a qualitative way. Related to the underlying model is the interaction with it. When this interaction has a normative counterpart in the real world we call it a procedure. The second theme of learning with computer simulation concerns learning goals. A learning goal is principally classified along three dimensions, which specify different aspects of the knowledge involved. The first dimension, knowledge category, indicates that a learning goal can address principles, concepts and/or facts (conceptual knowledge) or procedures (performance sequences). The second dimension, knowledge representation, captures the fact that knowledge can be represented in a more declarative (articulate, explicit), or in a more compiled (implicit) format, each one having its own advantages and drawbacks. The third dimension, knowledge scope, involves the learning goal's relation with the simulation domain; knowledge can be specific to a particular domain, or generalizable over classes of domains (generic). A more or less separate type of learning goal refers to knowledge acquisition skills that are pertinent to learning in an exploratory environment. Learning processes constitute the third theme. Learning processes are defined as cognitive actions of the learner. Learning processes can be classified using a multilevel scheme. The first (highest) of these levels gives four main categories: orientation, hypothesis generation, testing and evaluation. Examples of more specific processes are model exploration and output interpretation. The fourth theme of learning with computer simulations is learner activity. Learner activity is defined as the ‘physical’ interaction of the learner with the simulations (as opposed to the mental interaction that was described in the learning processes). Five main categories of learner activity are distinguished: defining experimental settings (variables, parameters etc.), interaction process choices (deciding a next step), collecting data, choice of data presentation and metacontrol over the simulation.
  • Van Donselaar, W., Koster, M., & Cutler, A. (2005). Exploring the role of lexical stress in lexical recognition. Quarterly Journal of Experimental Psychology, 58A(2), 251-273. doi:10.1080/02724980343000927.

    Abstract

    Three cross-modal priming experiments examined the role of suprasegmental information in the processing of spoken words. All primes consisted of truncated spoken Dutch words. Recognition of visually presented word targets was facilitated by prior auditory presentation of the first two syllables of the same words as primes, but only if they were appropriately stressed (e.g., OKTOBER preceded by okTO-); inappropriate stress, compatible with another word (e.g., OKTOBER preceded by OCto-, the beginning of octopus), produced inhibition. Monosyllabic fragments (e.g., OC-) also produced facilitation when appropriately stressed; if inappropriately stressed, they produced neither facilitation nor inhibition. The bisyllabic fragments that were compatible with only one word produced facilitation to semantically associated words, but inappropriate stress caused no inhibition of associates. The results are explained within a model of spoken-word recognition involving competition between simultaneously activated phonological representations followed by activation of separate conceptual representations for strongly supported lexical candidates; at the level of the phonological representations, activation is modulated by both segmental and suprasegmental information.
  • Van Berkum, J. J. A., Brown, C. M., Zwitserlood, P., Kooijman, V., & Hagoort, P. (2005). Anticipating upcoming words in discourse: Evidence from ERPs and reading times. Journal of Experimental Psychology: Learning, Memory, and Cognition, 31(3), 443-467. doi:10.1037/0278-7393.31.3.443.

    Abstract

    The authors examined whether people can use their knowledge of the wider discourse rapidly enough to anticipate specific upcoming words as a sentence is unfolding. In an event-related brain potential (ERP) experiment, subjects heard Dutch stories that supported the prediction of a specific noun. To probe whether this noun was anticipated at a preceding indefinite article, stories were continued with a gender-marked adjective whose suffix mismatched the upcoming noun's syntactic gender. Prediction-inconsistent adjectives elicited a differential ERP effect, which disappeared in a no-discourse control experiment. Furthermore, in self-paced reading, prediction-inconsistent adjectives slowed readers down before the noun. These findings suggest that people can indeed predict upcoming words in fluent discourse and, moreover, that these predicted words can immediately begin to participate in incremental parsing operations.
  • Van Turennout, M. (2002). Het benoemen van een object veroorzaakt langdurige veranderingen in het brein. Neuropraxis, 6(3), 77-81.
  • Van Halteren, H., Baayen, R. H., Tweedie, F., Haverkort, M., & Neijt, A. (2005). New machine learning methods demonstrate the existence of a human stylome. Journal of Quantitative Linguistics, 12(1), 65-77. doi:10.1080/09296170500055350.

    Abstract

    Earlier research has shown that established authors can be distinguished by measuring specific properties of their writings, their stylome as it were. Here, we examine writings of less experienced authors. We succeed in distinguishing between these authors with a very high probability, which implies that a stylome exists even in the general population. However, the number of traits needed for so successful a distinction is an order of magnitude larger than assumed so far. Furthermore, traits referring to syntactic patterns prove less distinctive than traits referring to vocabulary, but much more distinctive than expected on the basis of current generativist theories of language learning.
  • Van Wijk, C., & Kempen, G. (1985). From sentence structure to intonation contour: An algorithm for computing pitch contours on the basis of sentence accents and syntactic structure. In B. Müller (Ed.), Sprachsynthese: Zur Synthese von natürlich gesprochener Sprache aus Texten und Konzepten (pp. 157-182). Hildesheim: Georg Olms.
  • Van Berkum, J. J. A., & De Jong, T. (1991). Instructional environments for simulations. Education & Computing, 6(3/4), 305-358.

    Abstract

    The use of computer simulations in education and training can have substantial advantages over other approaches. In comparison with alternatives such as textbooks, lectures, and tutorial courseware, a simulation-based approach offers the opportunity to learn in a relatively realistic problem-solving context, to practise task performance without stress, to systematically explore both realistic and hypothetical situations, to change the time-scale of events, and to interact with simplified versions of the process or system being simulated. However, learners are often unable to cope with the freedom offered by, and the complexity of, a simulation. As a result many of them resort to an unsystematic, unproductive mode of exploration. There is evidence that simulation-based learning can be improved if the learner is supported while working with the simulation. Constructing such an instructional environment around simulations seems to run counter to the freedom the learner is allowed to in ‘stand alone’ simulations. The present article explores instructional measures that allow for an optimal freedom for the learner. An extensive discussion of learning goals brings two main types of learning goals to the fore: conceptual knowledge and operational knowledge. A third type of learning goal refers to the knowledge acquisition (exploratory learning) process. Cognitive theory has implications for the design of instructional environments around simulations. Most of these implications are quite general, but they can also be related to the three types of learning goals. For conceptual knowledge the sequence and choice of models and problems is important, as is providing the learner with explanations and minimization of error. For operational knowledge cognitive theory recommends learning to take place in a problem solving context, the explicit tracing of the behaviour of the learner, providing immediate feedback and minimization of working memory load. For knowledge acquisition goals, it is recommended that the tutor takes the role of a model and coach, and that learning takes place together with a companion. A second source of inspiration for designing instructional environments can be found in Instructional Design Theories. Reviewing these shows that interacting with a simulation can be a part of a more comprehensive instructional strategy, in which for example also prerequisite knowledge is taught. Moreover, information present in a simulation can also be represented in a more structural or static way and these two forms of presentation provoked to perform specific learning processes and learner activities by tutor controlled variations in the simulation, and by tutor initiated prodding techniques. And finally, instructional design theories showed that complex models and procedures can be taught by starting with central and simple elements of these models and procedures and subsequently presenting more complex models and procedures. Most of the recent simulation-based intelligent tutoring systems involve troubleshooting of complex technical systems. Learners are supposed to acquire knowledge of particular system principles, of troubleshooting procedures, or of both. Commonly encountered instructional features include (a) the sequencing of increasingly complex problems to be solved, (b) the availability of a range of help information on request, (c) the presence of an expert troubleshooting module which can step in to provide criticism on learner performance, hints on the problem nature, or suggestions on how to proceed, (d) the option of having the expert module demonstrate optimal performance afterwards, and (e) the use of different ways of depicting the simulated system. A selection of findings is summarized by placing them under the four themes we think to be characteristic of learning with computer simulations (see de Jong, this volume).
  • Van Valin Jr., R. D. (2005). Exploring the syntax-semantics interface. Cambridge University Press.

    Abstract

    Language is a system of communication in which grammatical structures function to express meaning in context. While all languages can achieve the same basic communicative ends, they each use different means to achieve them, particularly in the divergent ways that syntax, semantics and pragmatics interact across languages. This book looks in detail at how structure, meaning, and communicative function interact in human languages. Working within the framework of Role and Reference Grammar (RRG), Van Valin proposes a set of rules, called the ‘linking algorithm’, which relates syntactic and semantic representations to each other, with discourse-pragmatics playing a role in the linking. Using this model, he discusses the full range of grammatical phenomena, including the structures of simple and complex sentences, verb and argument structure, voice, reflexivization and extraction restrictions. Clearly written and comprehensive, this book will be welcomed by all those working on the interface between syntax, semantics and pragmatics.
  • van Geenhoven, V. (2002). Raised Possessors and Noun Incorporation in West Greenlandic. Natural Language & Linguistic Theory, 20(4), 759-821.

    Abstract

    This paper addresses the question of whether noun incorporation is a syntactically base-generated or a syntactically derived construction. Focusing on so-called 'raised possessors' in West Greenlandic noun incorporating constructions and presenting some new data, I discuss some problems that arise if we use the derivational framework of Bittner and Hale (1996) to analyze them. I show that if we make the predication relations in noun incorporating constructions overt in their syntax and if we adopt a dynamic approach to semantics, a base-generated syntactic input enriched with a coindexation system is all that we need to arrive at an adequate semantic interpretation of these constructions.
  • Van de Geer, J. P., Levelt, W. J. M., & Plomp, R. (1962). The connotation of musical consonance. Acta Psychologica, 20, 308-319.

    Abstract

    As a preliminary to further research on musical consonance an explanatory investigation was made on the different modes of judgment of musical intervals. This was done by way of a semantic differential. Subjects rated 23 intervals against 10 scales. In a factor analysis three factors appeared: pitch, evaluation and fusion. The relation between these factors and some physical characteristics has been investigated. The scale consonant-dissonant showed to be purely evaluative (in opposition to Stumpf's theory). This evaluative connotation is not in accordance with the musicological meaning of consonance. Suggestions to account for this difference have been given.
  • Van der Veer, G. C., Bagnara, S., & Kempen, G. (1991). Preface. Acta Psychologica, 78, ix. doi:10.1016/0001-6918(91)90002-H.
  • Verhagen, J. (2005). The role of the nonmodal auxiliary 'hebben' in Dutch as a second language. Zeitschrift für Literaturwissenschaft und Linguistik, 140, 109-127.

    Abstract

    The acquisition of non-modal auxiliaries has been assumed to constitute an important step in the acquisition of finiteness in Germanic languages (cf. Jordens/Dimroth 2005, Jordens 2004, Becker 2005). This paper focuses onthe role of the auxiliary hebben (>to have<) in the acquisition of Dutch as a second language. More specifically, it investigates whether learners' production of hebben is related to their acquisition of two phenomena commonly associated with finiteness, i.e., topicalization and negation. Data are presented from 16 Turkish and 36 Moroccan learners of Dutch who participated in an experiment involving production and imitation tasks. The production data suggest that learners use topicalization and post-verbal negation only after they have learned to produce the auxiliary hebben. The results from the imitation task indicate, that learners are more sensitive to topicalization and post-verbal negation in sentences with hebben than in sentences with lexical verbs. Interestingly this holds also for learners that did not show productive command of hebben in the production tasks. Thus, in general, the results of the experiment provide support for the idea that non-modal auxiliaries are crucial in the acquisition of (certain properties of) finiteness.
  • Verhagen, J. (2005). The role of the nonmodal auxiliary 'hebben' in Dutch as a second language. Toegepaste Taalwetenschap in Artikelen, 73, 41-52.
  • Vigliocco, G., Lauer, M., Damian, M. F., & Levelt, W. J. M. (2002). Semantic and syntactic forces in noun phrase production. Journal of Experimental Psychology: Learning, Memory and Cognition, 28(1), 46-58. doi:10.1037//0278-7393.28.1.46.

    Abstract

    Three experiments investigated semantic and syntactic effects in the production of phrases in Dutch. Bilingual participants were presented with English nouns and were asked to produce an adjective + noun phrase in Dutch including the translation of the noun. In 2 experiments, the authors blocked items by either semantic category or grammatical gender. Participants performed the task slower when the target nouns were of the same semantic category than when they were from different categories and faster when the target nouns had the same gender than when they had different genders. In a final experiment, both manipulations were crossed. The authors replicated the results of the first 2 experiments, and no interaction was found. These findings suggest a feedforward flow of activation between lexico-semantic and lexico-syntactic information.
  • Vigliocco, G., Vinson, D. P., Damian, M. F., & Levelt, W. J. M. (2002). Semantic distance effects on object and action naming. Cognition, 85, B61-B69. doi:10.1016/S0010-0277(02)00107-5.

    Abstract

    Graded interference effects were tested in a naming task, in parallel for objects and actions. Participants named either object or action pictures presented in the context of other pictures (blocks) that were either semantically very similar, or somewhat semantically similar or semantically dissimilar. We found that naming latencies for both object and action words were modulated by the semantic similarity between the exemplars in each block, providing evidence in both domains of graded semantic effects.
  • Vonk, W. (2002). Zin in tekst. Psycholinguïstisch onderzoek naar het begrijpen van taal. Gramma/TTT, 8, 267-284.
  • De Vos, C. (2005). Cataphoric pronoun resolution (Unpublished bachelor thesis). Nijmegen: Department of Linguistics, Radboud University.

    Abstract

    Processing of cataphoric coreferential relationships.
  • Vosse, T., & Kempen, G. (1991). A hybrid model of human sentence processing: Parsing right-branching, center-embedded and cross-serial dependencies. In M. Tomita (Ed.), Proceedings of the Second International Workshop on Parsing Technologies.
  • Warner, N., Smits, R., McQueen, J. M., & Cutler, A. (2005). Phonological and statistical effects on timing of speech perception: Insights from a database of Dutch diphone perception. Speech Communication, 46(1), 53-72. doi:10.1016/j.specom.2005.01.003.

    Abstract

    We report detailed analyses of a very large database on timing of speech perception collected by Smits et al. (Smits, R., Warner, N., McQueen, J.M., Cutler, A., 2003. Unfolding of phonetic information over time: A database of Dutch diphone perception. J. Acoust. Soc. Am. 113, 563–574). Eighteen listeners heard all possible diphones of Dutch, gated in portions of varying size and presented without background noise. The present report analyzes listeners’ responses across gates in terms of phonological features (voicing, place, and manner for consonants; height, backness, and length for vowels). The resulting patterns for feature perception differ from patterns reported when speech is presented in noise. The data are also analyzed for effects of stress and of phonological context (neighboring vowel vs. consonant); effects of these factors are observed to be surprisingly limited. Finally, statistical effects, such as overall phoneme frequency and transitional probabilities, along with response biases, are examined; these too exercise only limited effects on response patterns. The results suggest highly accurate speech perception on the basis of acoustic information alone.
  • Warner, N., Kim, J., Davis, C., & Cutler, A. (2005). Use of complex phonological patterns in speech processing: Evidence from Korean. Journal of Linguistics, 41(2), 353-387. doi:10.1017/S0022226705003294.

    Abstract

    Korean has a very complex phonology, with many interacting alternations. In a coronal-/i/ sequence, depending on the type of phonological boundary present, alternations such as palatalization, nasal insertion, nasal assimilation, coda neutralization, and intervocalic voicing can apply. This paper investigates how the phonological patterns of Korean affect processing of morphemes and words. Past research on languages such as English, German, Dutch, and Finnish has shown that listeners exploit syllable structure constraints in processing speech and segmenting it into words. The current study shows that in parsing speech, listeners also use much more complex patterns that relate the surface phonological string to various boundaries.
  • Warner, N., & Weber, A. (2002). Stop epenthesis at syllable boundaries. In J. H. L. Hansen, & B. Pellom (Eds.), 7th International Conference on Spoken Language Processing (ICSLP2002 - INTERSPEECH 2002) (pp. 1121-1124). ISCA Archive.

    Abstract

    This paper investigates the production and perception of epenthetic stops at syllable boundaries in Dutch and compares the experimental data with lexical statistics for Dutch and English. This extends past work on epenthesis in coda position [1]. The current work is particularly informative regarding the question of phonotactic constraints’ influence on parsing of speech variability.
  • Warner, N., Jongman, A., & Mücke, D. (2002). Variability in direction of dorsal movement during production of /l/. In J. H. L. Hansen, & B. Pellom (Eds.), 7th International Conference on Spoken Language Processing (ICSLP2002 - INTERSPEECH 2002) (pp. 1089-1092). ISCA Archive.

    Abstract

    This paper presents articulatory data on the production of /l/ in various environments in Dutch, and shows that the direction of movement of the tongue dorsum varies across environments. This makes it impossible to measure tongue position at the peak of the dorsal gesture. We argue for an alternative method in such cases: measurement of position of one articulator at a time point defined by the gesture of another. We present new data measured this way which confirms a previous finding on the articulation of Dutch /l/.
  • Wassenaar, M., & Hagoort, P. (2005). Word-category violations in patients with Broca's aphasia: An ERP study. Brain and Language, 92, 117-137. doi:10.1016/j.bandl.2004.05.011.

    Abstract

    An event-related brain potential experiment was carried out to investigate on-line syntactic processing in patients with Broca’s aphasia. Subjects were visually presented with sentences that were either syntactically correct or contained violations of word-category. Three groups of subjects were tested: Broca patients (N=11), non-aphasic patients with a right hemisphere (RH) lesion (N=9), and healthy aged-matched controls (N=15). Both control groups appeared sensitive to the violations of word-category as shown by clear P600/SPS effects. The Broca patients displayed only a very reduced and delayed P600/SPS effect. The results are discussed in the context of a lexicalist parsing model. It is concluded that Broca patients are hindered to detect on-line violations of word-category, if word class information is incomplete or delayed available.
  • Wassenaar, M. (2005). Agrammatic comprehension: An electrophysiological approach. PhD Thesis, Radboud University Nijmegen, Nijmegen. doi:10.17617/2.60340.

    Abstract

    This dissertation focuses on syntactic comprehension problems in patients with Broca's aphasia from an electrophysiological perspective. The central objective of this dissertation was to further explore what syntax-related event-related brain potential (ERP) effects can reveal about the nature of the deficit that underlies syntactic comprehension problems in patients with Broca's aphasia. Chapter two to four describe experiments in which event-related brain potentials were recorded while subjects (Broca patients, non-aphasic patients with a right-hemisphere lesion, and healthy elderly controls) were presented with sentences that contained either violations of syntactic constraints or were syntactically correct. Chapter two investigates ERP effects of subject-verb agreement violations in the different subject groups, and seeks to answer the following questions: Do agrammatic comprehenders show sensitivity to subject-verb agreement violations as indicated by a syntax-related ERP effect? In addition, does the severity of the syntactic comprehension impairment in the Broca patients affect the ERP responses? Chapter three describes an investigation of whether Broca patients show sensitivity to violations of word order as indicated by a syntax-related ERP effect, and whether the ERP responses in the Broca patients are affected by the severity of their syntactic comprehension impairment. Chapter four reports on ERP effects of violations of word-category. In addition, also a semantic violation condition was added to track possible dissociations in the sensitivity to semantic and syntactic information in the Broca patients. Chapter five describes the development of a paradigm in which the electrophysiological approach and the classical sentence-picture matching approach are combined. In this chapter, the ERP method is applied to study on-line thematic role assignment in Broca patients during sentence-picture matching. Also the relation between ERP effects and behavioral responses is pursued. Finally, Chapter 6 provides a summary of the main findings of the experiments and a general discussion.

    Additional information

    full text via Radboud Repository
  • Weber, A. (2002). Assimilation violation and spoken-language processing: A supplementary report. Language and Speech, 45, 37-46. doi:10.1177/00238309020450010201.

    Abstract

    Previous studies have shown that spoken-language processing is inhibited by violation of obligatory regressive assimilation. Weber (2001) replicated this inhibitory effect in a phoneme-monitoring study examining regressive place assimilation of nasals, but found facilitation for violation of progressive assimilation. German listeners detected the velar fricative [x] more quickly when fricative assimilation was violated (e.g., *[bIxt] or *[blInx@n]) than when no violation occurred (e.g., [baxt] or [blu:x@n]). It was argued that a combination of two factors caused facilitation:(1) progressive assimilation creates different restrictions for the monitoring target than regressive assimilation does, and (2) the sequences violating assimilation (e.g., *[Ix]) are novel for German listeners and therefore facilitate fricative detection (novel popout). The present study tested progressive assimilation violation in non-novel sequences using the palatal fricative [C]. Stimuli either violated fricative assimilation (e.g., *[ba:C@l ]) or did not (e.g., [bi: C@l ]). This manipulation does not create novel sequences: sequences like *[a:C] can occur across word boundaries, while *[Ix] cannot. No facilitation was found. However, violation also did not significantly inhibit processing. The results confirm that facilitation depends on the combination of progressive assimilation with novelty of the sequence.
  • Wegener, C. (2005). Major word classes in Savosavo. Grazer Linguistische Studien, 64, 29-52.
  • Weissenborn, J., & Stralka, R. (1984). Das Verstehen von Mißverständnissen. Eine ontogenetische Studie. In Zeitschrift für Literaturwissenschaft und Linguistik (pp. 113-134). Stuttgart: Metzler.
  • Weissenborn, J. (1984). La genèse de la référence spatiale en langue maternelle et en langue seconde: similarités et différences. In G. Extra, & M. Mittner (Eds.), Studies in second language acquisition by adult immigrants (pp. 262-286). Tilburg: Tilburg University.
  • Weissenborn, J. (1988). Von der demonstratio ad oculos zur Deixis am Phantasma. Die Entwicklung der lokalen Referenz bei Kindern. In Karl Bühler's Theory of Language. Proceedings of the Conference held at Kirchberg, August 26, 1984 and Essen, November 21–24, 1984 (pp. 257-276). Amsterdam: Benjamins.
  • Wittenburg, P., Skiba, R., & Trilsbeek, P. (2005). The language archive at the MPI: Contents, tools, and technologies. Language Archives Newsletter, 5, 7-9.
  • Wittenburg, P., Kita, S., & Brugman, H. (2002). Crosslinguistic studies of multimodal communication.
  • Wittenburg, P., Peters, W., & Drude, S. (2002). Analysis of lexical structures from field linguistics and language engineering. In M. R. González, & C. P. S. Araujo (Eds.), Third international conference on language resources and evaluation (pp. 682-686). Paris: European Language Resources Association.

    Abstract

    Lexica play an important role in every linguistic discipline. We are confronted with many types of lexica. Depending on the type of lexicon and the language we are currently faced with a large variety of structures from very simple tables to complex graphs, as was indicated by a recent overview of structures found in dictionaries from field linguistics and language engineering. It is important to assess these differences and aim at the integration of lexical resources in order to improve lexicon creation, exchange and reuse. This paper describes the first step towards the integration of existing structures and standards into a flexible abstract model.
  • Wittenburg, P., & Broeder, D. (2002). Metadata overview and the semantic web. In P. Austin, H. Dry, & P. Wittenburg (Eds.), Proceedings of the international LREC workshop on resources and tools in field linguistics. Paris: European Language Resources Association.

    Abstract

    The increasing quantity and complexity of language resources leads to new management problems for those that collect and those that need to preserve them. At the same time the desire to make these resources available on the Internet demands an efficient way characterizing their properties to allow discovery and re-use. The use of metadata is seen as a solution for both these problems. However, the question is what specific requirements there are for the specific domain and if these are met by existing frameworks. Any possible solution should be evaluated with respect to its merit for solving the domain specific problems but also with respect to its future embedding in “global” metadata frameworks as part of the Semantic Web activities.
  • Wittenburg, P., Peters, W., & Broeder, D. (2002). Metadata proposals for corpora and lexica. In M. Rodriguez González, & C. Paz Suárez Araujo (Eds.), Third international conference on language resources and evaluation (pp. 1321-1326). Paris: European Language Resources Association.
  • Wittenburg, P., Broeder, D., Offenga, F., & Willems, D. (2002). Metadata set and tools for multimedia/multimodal language resources. In M. Maybury (Ed.), Proceedings of the 3rd International Conference on Language Resources and Evaluation (LREC 2002). Workshop on Multimodel Resources and Multimodel Systems Evaluation. (pp. 9-13). Paris: European Language Resources Association.
  • Wittenburg, P., Mosel, U., & Dwyer, A. (2002). Methods of language documentation in the DOBES program. In P. Austin, H. Dry, & P. Wittenburg (Eds.), Proceedings of the international LREC workshop on resources and tools in field linguistics (pp. 36-42). Paris: European Language Resources Association.
  • Wohlgemuth, J., & Dirksmeyer, T. (Eds.). (2005). Bedrohte Vielfalt. Aspekte des Sprach(en)tods – Aspects of language death. Berlin: Weißensee.

    Abstract

    About 5,000 languages are spoken in the world today. More than half of them have less than 10,000 speakers, a quarter of them even fewer than 1,000. The majority of these “small” languages will not live to see the end of this century; some estimates predict that no more than a dozen languages will still be spoken by the turn of the next millennium. This collection of papers approaches the subject of language extinction through five major topics: general aspects of language death, case studies, endangered subsystems, language protection and revitalization, language ecology. In 24 articles, the authors address the causes, manifestations, and consequences of language endangerment and extinction as well as the linguistic and social changes associated with it, drawing examples from a large number of languages.
  • Zeshan, U. (2005). Sign languages. In M. Haspelmath, M. S. Dryer, D. Gil, & B. Comrie (Eds.), The world atlas of language structures (pp. 558-559). Oxford: Oxford University Press.
  • Zeshan, U. (2005). Question particles in sign languages. In M. Haspelmath, M. S. Dryer, D. Gil, & B. Comrie (Eds.), The world atlas of language structures (pp. 564-567). Oxford: Oxford University Press.
  • Zeshan, U., & Panda, S. (2005). Professional course in Indian sign language. Mumbai: Ali Yavar Jung National Institute for the Hearing Handicapped.
  • Zeshan, U., Pfau, R., & Aboh, E. (2005). When a wh-word is not a wh-word: the case of Indian sign language. In B. Tanmoy (Ed.), Yearbook of South Asian languages and linguistics 2005 (pp. 11-43). Berlin: Mouton de Gruyter.
  • Zeshan, U., Vasishta, M. N., & Sethna, M. (2005). Implementation of Indian Sign Language in educational settings. Asia Pacific Disability Rehabilitation Journal, 16(1), 16-40.

    Abstract

    This article reports on several sub-projects of research and development related to the use of Indian Sign Language in educational settings. In many countries around the world, sign languages are now recognised as the legitimate, full-fledged languages of the deaf communities that use them. In India, the development of sign language resources and their application in educational contexts, is still in its initial stages. The work reported on here, is the first principled and comprehensive effort of establishing educational programmes in Indian Sign Language at a national level. Programmes are of several types: a) Indian Sign Language instruction for hearing people; b) sign language teacher training programmes for deaf people; and c) educational materials for use in schools for the Deaf. The conceptual approach used in the programmes for deaf students is known as bilingual education, which emphasises the acquisition of a first language, Indian Sign Language, alongside the acquisition of spoken languages, primarily in their written form.
  • Zeshan, U. (2005). Irregular negatives in sign languages. In M. Haspelmath, M. S. Dryer, D. Gil, & B. Comrie (Eds.), The world atlas of language structures (pp. 560-563). Oxford: Oxford University Press.
  • Zhang, J., Bao, S., Furumai, R., Kucera, K. S., Ali, A., Dean, N. M., & Wang, X.-F. (2005). Protein phosphatase 5 is required for ATR-mediated checkpoint activation. Molecular and Cellular Biology, 25, 9910-9919. doi:10.1128/​MCB.25.22.9910-9919.2005.

    Abstract

    In response to DNA damage or replication stress, the protein kinase ATR is activated and subsequently transduces genotoxic signals to cell cycle control and DNA repair machinery through phosphorylation of a number of downstream substrates. Very little is known about the molecular mechanism by which ATR is activated in response to genotoxic insults. In this report, we demonstrate that protein phosphatase 5 (PP5) is required for the ATR-mediated checkpoint activation. PP5 forms a complex with ATR in a genotoxic stress-inducible manner. Interference with the expression or the activity of PP5 leads to impairment of the ATR-mediated phosphorylation of hRad17 and Chk1 after UV or hydroxyurea treatment. Similar results are obtained in ATM-deficient cells, suggesting that the observed defect in checkpoint signaling is the consequence of impaired functional interaction between ATR and PP5. In cells exposed to UV irradiation, PP5 is required to elicit an appropriate S-phase checkpoint response. In addition, loss of PP5 leads to premature mitosis after hydroxyurea treatment. Interestingly, reduced PP5 activity exerts differential effects on the formation of intranuclear foci by ATR and replication protein A, implicating a functional role for PP5 in a specific stage of the checkpoint signaling pathway. Taken together, our results suggest that PP5 plays a critical role in the ATR-mediated checkpoint activation.
  • Zwitserlood, I. (2002). Klassifikatoren in der Niederländischen Gebärdensprache (NGT). In H. Leuniger, & K. Wempe (Eds.), Gebärdensprachlinguistik 2000. Theorie und Anwendung. Vorträge vom Symposium "Gebärdensprachforschung im deutschsprachigem Raum", Frankfurt a.M., 11.-13. Juni 1999 (pp. 113-126). Hamburg: Signum Verlag.
  • Zwitserlood, I. (2002). The complex structure of ‘simple’ signs in NGT. In J. Van Koppen, E. Thrift, E. Van der Torre, & M. Zimmermann (Eds.), Proceedings of ConSole IX (pp. 232-246).

    Abstract

    In this paper, I argue that components in a set of simple signs in Nederlandse Gebarentaal (also called Sign Language of the Netherlands; henceforth: NGT), i.e. hand configuration (including orientation), movement and place of articulation, can also have morphological status. Evidence for this is provided by: firstly, the fact that handshape, orientation, movement and place of articulation show regular meaningful patterns in signs, which patterns also occur in newly formed signs, and secondly, the gradual change of formerly noninflecting predicates into inflectional predicates. The morphological complexity of signs can best be accounted for in autosegmental morphological templates.

Share this page