Publications

Abstract

In the Smaldino et al. study ‘Sigmoidal Acquisition Curves are Good Indicators of Conformist Transmission’, our original findings regarding the conditional validity of using population-level sigmoidal acquisition curves as means to evidence individual-level conformity are contested. We acknowledge the identification of useful nuances, yet conclude that our original findings remain relevant for the study of conformist learning mechanisms. Replying to: Smaldino, P. E., Aplin, L. M. & Farine, D. R. Sigmoidal Acquisition Curves Are Good Indicators of Conformist Transmission. Sci. Rep. 8, https://doi.org/10.1038/s41598-018-30248-5 (2018).

Abstract

Verbal working memory (VWM), the ability to maintain and manipulate representations of speech sounds over short periods, is held by some influential models to be independent from the systems responsible for language production and comprehension [e.g., Baddeley, A. D. Working memory, thought, and action. New York, NY: Oxford University Press, 2007]. We explore the alternative hypothesis that maintenance in VWM is subserved by temporary activation of the language production system [Acheson, D. J., & MacDonald, M. C. Verbal working memory and language production: Common approaches to the serial ordering of verbal information. Psychological Bulletin, 135, 50–68, 2009b]. Specifically, we hypothesized that for stimuli lacking a semantic representation (e.g., nonwords such as mun), maintenance in VWM can be achieved by cycling information back and forth between the stages of phonological encoding and articulatory planning. First, fMRI was used to identify regions associated with two different stages of language production planning: the posterior superior temporal gyrus (pSTG) for phonological encoding (critical for VWM of nonwords) and the middle temporal gyrus (MTG) for lexical–semantic retrieval (not critical for VWM of nonwords). Next, in the same subjects, these regions were targeted with repetitive transcranial magnetic stimulation (rTMS) during language production and VWM task performance. Results showed that rTMS to the pSTG, but not the MTG, increased error rates on paced reading (a language production task) and on delayed serial recall of nonwords (a test of VWM). Performance on a lexical–semantic retrieval task (picture naming), in contrast, was significantly sensitive to rTMS of the MTG. Because rTMS was guided by language production-related activity, these results provide the first causal evidence that maintenance in VWM directly depends on the long-term representations and processes used in speech production.

Abstract

The influence of semantic processing on the serial ordering of items in short-term memory was explored using a novel dual-task paradigm. Participants engaged in 2 picture-judgment tasks while simultaneously performing delayed serial recall. List material varied in the presence of phonological overlap (Experiments 1 and 2) and in semantic content (concrete words in Experiment 1 and 3; nonwords in Experiments 2 and 3). Picture judgments varied in the extent to which they required accessing visual semantic information (i.e., semantic categorization and line orientation judgments). Results showed that, relative to line-orientation judgments, engaging in semantic categorization judgments increased the proportion of item-ordering errors for concrete lists but did not affect error proportions for nonword lists. Furthermore, although more ordering errors were observed for phonologically similar relative to dissimilar lists, no interactions were observed between the phonological overlap and picture-judgment task manipulations. These results demonstrate that lexical-semantic representations can affect the serial ordering of items in short-term memory. Furthermore, the dual-task paradigm provides a new method for examining when and how semantic representations affect memory performance.

Abstract

Research on written language comprehension has generally assumed that the phonological properties of a word have little effect on sentence comprehension beyond the processes of word recognition. Two experiments investigated this assumption. Participants silently read relative clauses in which two pairs of words either did or did not have a high degree of phonological overlap. Participants were slower reading and less accurate comprehending the overlap sentences compared to the non-overlapping controls, even though sentences were matched for plausibility and differed by only two words across overlap conditions. A comparison across experiments showed that the overlap effects were larger in the more difficult object relative than in subject relative sentences. The reading patterns showed that phonological representations affect not only memory for recently encountered sentences but also the developing sentence interpretation during on-line processing. Implications for theories of sentence processing and memory are discussed. Highlights The work investigates the role of phonological information in sentence comprehension, which is poorly understood. ► Subjects read object and subject relative clauses +/- phonological overlap in two pairs of words. ► Unique features of the study were online reading measures and pinpointed overlap locations. ► Phonological overlap slowed reading speed and impaired sentence comprehension, especially for object relatives. ► The results show a key role for phonological information during online comprehension, not just later sentence memory.

Abstract

Ambiguity surrounds the existence and morphology of the human forniceal commissure. We combine advanced in-vivo tractography, multidirectional ex-vivo fiber dissection, and multiplanar histological analysis to characterize this structure’s anatomy. Across all 178 subjects, in-vivo fiber dissection based on the Human Connectome Project 7 T MRI data identifies no interhemispheric connections between the crura fornicis. Multidirectional ex-vivo fiber dissection under the operating microscope demonstrates the psalterium as a thin soft-tissue membrane spanning between the right and left crus fornicis, but exposes no commissural fibers. Multiplanar histological analysis with myelin and Bielchowsky silver staining, however, visualizes delicate cruciform fibers extending between the crura fornicis, enclosed by connective tissue, the psalterium. The human forniceal commissure is therefore much more delicate than previously described and presented in anatomical textbooks. This finding is consistent with the observed phylogenetic trend of a reduction of the forniceal commissure in non-human primates compared to non-primate eutherian mammals.

Abstract

Alterations in brain size and organization represent some of the most distinctive changes in the emergence of our species. Yet, there is limited understanding of how genetic factors contributed to altered neuroanatomy during human evolution. Here, we analyze neuroimaging and genetic data from up to 30,000 people in the UK Biobank and integrate with genomic annotations for different aspects of human evolution, including those based on ancient DNA and comparative genomics. We show that previously reported signals of recent polygenic selection for cortical anatomy are not replicable in a more ancestrally homogeneous sample. We then investigate relationships between evolutionary annotations and common genetic variants shaping cortical surface area and white-matter connectivity for each hemisphere. Our analyses identify single-nucleotide polymorphism heritability enrichment in human-gained regulatory elements that are active in early brain development, affecting surface areas of several parts of the cortex, including left-hemispheric speech-associated regions. We also detect heritability depletion in genomic regions with Neanderthal ancestry for connectivity of the uncinate fasciculus; this is a white-matter tract involved in memory, language, and socioemotional processing with relevance to neuropsychiatric disorders. Finally, we show that common genetic loci associated with left-hemispheric pars triangularis surface area overlap with a human-gained enhancer and affect regulation of ZIC4, a gene implicated in neurogenesis. This work demonstrates how genomic investigations of present-day neuroanatomical variation can help shed light on the complexities of our evolutionary past.

Abstract

This study sought to identify tumor characteristics that associate with regional lymph node metastases in squamous cell carcinomas originating in the upper gingiva.

Abstract

In an influential paper (“Rule Learning by Seven-Month-Old Infants”), Marcus, Vijayan, Rao and Vishton claimed that connectionist models cannot account for human success at learning tasks that involved generalization of abstract knowledge such as grammatical rules. This claim triggered a heated debate, centered mostly around variants of the Simple Recurrent Network model. In our work, we revisit this unresolved debate and analyze the underlying issues from a different perspective. We argue that, in order to simulate human-like learning of grammatical rules, a neural network model should not be used as a tabula rasa, but rather, the initial wiring of the neural connections and the experience acquired prior to the actual task should be incorporated into the model. We present two methods that aim to provide such initial state: a manipulation of the initial connections of the network in a cognitively plausible manner (concretely, by implementing a “delay-line” memory), and a pre-training algorithm that incrementally challenges the network with novel stimuli. We implement such techniques in an Echo State Network (ESN), and we show that only when combining both techniques the ESN is able to learn truly general identity rules. Finally, we discuss the relation between these cognitively motivated techniques and recent advances in Deep Learning.

Abstract

The automatic retuning of phoneme categories to better adapt to the speech of a novel talker has been extensively documented across various (neurotypical) populations, including both adults and children. However, no studies have examined auditory perceptual learning effects in populations atypical in perceptual, social, and language processing for communication, such as populations with autism. Employing a classic lexically-guided perceptual learning paradigm, the present study investigated perceptual learning effects in Australian English autistic and non-autistic adults. The findings revealed that automatic attunement to existing phoneme categories was not activated in the autistic group in the same manner as for non-autistic control subjects. Specifically, autistic adults were able to both successfully discern lexical items and to categorize speech sounds; however, they did not show effects of perceptual retuning to talkers. These findings may have implications for the application of current sensory theories (e.g., Bayesian decision theory) to speech and language processing by autistic individuals.
Lay Summary

Lexically guided perceptual learning assists in the disambiguation of speech from a novel talker. The present study established that while Australian English autistic adult listeners were able to successfully discern lexical items and categorize speech sounds in their native language, perceptual flexibility in updating speaker-specific phonemic knowledge when exposed to a novel talker was not available. Implications for speech and language processing by autistic individuals as well as current sensory theories are discussed.

Abstract

Different languages map semantic elements of spatial relations onto different lexical and syntactic units. These crosslinguistic differences raise important questions for language development in terms of how this variation is learned by children. We investigated how Turkish-, English-, and Japanese-speaking children (mean age 3;8) package the semantic elements of Manner and Path onto syntactic units when both the Manner and the Path of the moving Figure occur simultaneously and are salient in the event depicted. Both universal and language-specific patterns were evident in our data. Children used the semantic-syntactic mappings preferred by adult speakers of their own languages, and even expressed subtle syntactic differences that encode different relations between Manner and Path in the same way as their adult counterparts (i.e., Manner causing vs. incidental to Path). However, not all types of semantics-syntax mappings were easy for children to learn (e.g., expressing Manner and Path elements in two verbal clauses). In such cases, Turkish- and Japanese-speaking children frequently used syntactic patterns that were not typical in the target language but were similar to patterns used by English-speaking children, suggesting some universal influence. Thus, both language-specific and universal tendencies guide the development of complex spatial expressions.

Abstract

Attention is a core cognitive function that filters and selects behaviourally relevant information in the environment. The cortical mapping of attentional systems identified two segregated networks that mediate stimulus-driven and goal-driven processes, the Ventral and the Dorsal Attention Networks (VAN, DAN). Deep brain electrophysiological recordings, behavioral data from phylogenetic distant species, and observations from human brain pathologies challenge purely corticocentric models. Here, we used advanced methods of functional alignment applied to resting-state functional connectivity analyses to map the subcortical architecture of the Ventral and Dorsal Attention Networks. Our investigations revealed the involvement of the pulvinar, the superior colliculi, the head of caudate nuclei, and a cluster of brainstem nuclei relevant to both networks. These nuclei are densely connected structural network hubs, as revealed by diffusion-weighted imaging tractography. Their projections establish interrelations with the acetylcholine nicotinic receptor as well as dopamine and serotonin transporters, as demonstrated in a spatial correlation analysis with a normative atlas of neurotransmitter systems. This convergence of functional, structural, and neurochemical evidence provides a comprehensive framework to understand the neural basis of attention across different species and brain diseases.

Abstract

Whilst certain verbs may appear in both the intransitive inchoative and the transitive causative constructions (The ball rolled/The man rolled the ball), others may appear in only the former (The man laughed/*The joke laughed the man). Some accounts argue that children acquire these restrictions using only (or mainly) statistical learning mechanisms such as entrenchment and pre-emption. Others have argued that verb semantics are also important. To test these competing accounts, adults (Experiment 1) and children aged 5–6 and 9–10 (Experiment 2) were taught novel verbs designed to be construed — on the basis of their semantics — as either intransitive-only or alternating. In support of the latter claim, participants' grammaticality judgments revealed that even the youngest group respected these semantic constraints. Frequency (entrenchment) effects were observed for familiar, but not novel, verbs (Experiment 1). We interpret these findings in the light of a new theoretical account designed to yield effects of both verb semantics and entrenchment/pre-emption.

Abstract

This article examines the grammar, use and meaning of fifteen verbs used in the Basic Locative Construction (BLC) of Likpe — a Ghana-Togo-Mountain language. The verbs fall into four semantic subclasses: (a) basic topological relations: t 'be.at', tk 'be.on', kpé 'be.in', and fi 'be.near'; (b) postural verbs: sí 'sit', ny 'stand', fáka 'hang', yóma 'hang', kps 'lean', fus 'squat', and labe 'lie'; (c) “distribution” verbs: kpó 'be spread, heaped,' and tí 'be covered'; and (d) “adhesion” verbs: má 'be griped, be fixed', mánkla 'be stuck to'. Likpe locative predications reflect an ontological commitment to the overall topological relation between Figure and Ground and are not focused just on the Figure or the Ground. Various factors determine the choice of “competing” verbs for particular scenarios: animacy, nonindividuation of the Figure, permanency of the configuration and the speaker's desire to be referentially precise or to present stereotypical information. It is demonstrated that in situations where there is a choice, speakers tend to use the more general verbs (stereotype information). The implications of this tendency for the development of a language from a multiverb language using several verbs (e.g., 15) in its BLC to using only a small-set of verbs in its BLC, just as some of Likpe's neighbors have done, are considered.

Abstract

Ewe verbs covering the cutting and breaking domain divide into four morpho-syntactic classes that can be ranked according to agentivity. We demonstrate that the highly non-agentive break verbs participate in the causative-inchoative alternation while the highly agentive cut verbs do not, as expected from Guerssel et al.'s (1985) hypothesis. However, four verbs tso 'cut with precision', 'cut', 'snap-off', and dze 'split', are used transitively when an instrument is required for the severance to be effected, and intransitively when not. We reject a lexicalist analysis that would postulate polysemy for these verbs and argue for a construction approach.

Abstract

This special issue is devoted to a relatively neglected topic in linguistics, namely the verbal component of locative statements. English tends, of course, to use a simple copula in utterances like “The cup is on the table”, but many languages, perhaps as many as half of the world's languages, have a set of alternate verbs, or alternate verbal affixes, which contrast in this slot. Often these are classificatory verbs of 'sitting', 'standing' and 'lying'. For this reason, perhaps, Aristotle listed position among his basic (“noncomposite”) categories.

Abstract

Particles are little words that speakers use to signal the illocutionary force of utterances and/or express their attitude towards elements of the communicative situation, e.g. the addresses. This paper presents an overview of the classification, meaning and use of utterance particles in Ewe. It argues that they constitute a grammatical word class on functional and distributional grounds. The paper calls for a cross-cultural investigation of particles, especially in Africa, where they have been neglected for far too long.

Abstract

Previous research suggests an association of loneliness and social isolation (LNL-ISO) with schizophrenia. Here, we demonstrate a LNL-ISO polygenic score contribution to schizophrenia risk in an independent case-control sample (N = 3,488). We then subset schizophrenia predisposing variation based on its effect on LNL-ISO. We find that genetic variation with concordant effects in both phenotypes shows significant SNP-based heritability enrichment, higher polygenic contribution in females, and positive covariance with mental disorders such as depression, anxiety, attention-deficit hyperactivity disorder, alcohol dependence, and autism. Conversely, genetic variation with discordant effects only contributes to schizophrenia risk in males and is negatively correlated with those disorders. Mendelian randomization analyses demonstrate a plausible bi-directional causal relationship between LNL-ISO and schizophrenia, with a greater effect of LNL-ISO liability on schizophrenia than vice versa. These results illustrate the genetic footprint of LNL-ISO on schizophrenia.

Abstract

ARHGEF39 was previously implicated in developmental language disorder (DLD) via a functional polymorphism that can disrupt post-transcriptional regulation by microRNAs. ARHGEF39 is part of the family of Rho guanine nucleotide exchange factors (RhoGEFs) that activate small Rho GTPases to regulate a wide variety of cellular processes. However, little is known about the function of ARHGEF39, or how its function might contribute to neurodevelopment or related disorders. Here, we explore the molecular function of ARHGEF39 and show that it activates the Rho GTPase RHOA and that high ARHGEF39 expression in cell cultures leads to an increase of detached cells. To explore its role in neurodevelopment, we analyse published single cell RNA-sequencing data and demonstrate that ARHGEF39 is a marker gene for proliferating neural progenitor cells and that it is co-expressed with genes involved in cell division. This suggests a role for ARHGEF39 in neurogenesis in the developing brain. The co-expression of ARHGEF39 with other RHOA-regulating genes supports RHOA as substrate of ARHGEF39 in neural cells, and the involvement of RHOA in neuropsychiatric disorders highlights a potential link between ARHGEF39 and neurodevelopment and disorder. Understanding the GTPase substrate, co-expression network, and processes downstream of ARHGEF39 provide new avenues for exploring the mechanisms by which altered expression levels of ARHGEF39 may contribute to neurodevelopment and associated disorders.

Abstract

The current study investigated which time components of rapid automatized naming (RAN) predict group differences between dyslexic and non-dyslexic readers (matched for age and reading level), and how these components relate to different reading measures. Subjects performed two RAN tasks (letters and objects), and data were analyzed through a response time analysis. Our results demonstrated that impaired RAN performance in dyslexic readers mainly stem from enhanced inter-item pause times and not from difficulties at the level of post-access motor production (expressed as articulation rates). Moreover, inter-item pause times account for a significant proportion of variance in reading ability in addition to the effect of phonological awareness in the dyslexic group. This suggests that non-phonological factors may lie at the root of the association between RAN inter-item pauses and reading ability. In normal readers, RAN performance was associated with reading ability only at early ages (i.e. in the reading-matched controls), and again it was the RAN inter-item pause times that explain the association.

Abstract

In the present study, the authors investigate how some visual factors related to early stages of visual-object naming modulate naming performance in dyslexia. The performance of dyslexic children was compared with 2 control groups—normal readers matched for age and normal readers matched for reading level—while performing a discrete naming task in which color and dimensionality of the visually presented objects were manipulated. The results showed that 2-dimensional naming performance improved for color representations in control readers but not in dyslexics. In contrast to control readers, dyslexics were also insensitive to the stimulus's dimensionality. These findings are unlikely to be explained by a phonological processing problem related to phonological access or retrieval but suggest that dyslexics have a lower capacity for coding and decoding visual surface features of 2-dimensional representations or problems with the integration of visual information stored in long-term memory.

Abstract

This article summarizes some of the important findings from research evaluating the relationship between poor rapid naming and impaired reading performance. Substantial evidence shows that dyslexic readers have problems with rapid naming of visual items. Early research assumed that this was a consequence of phonological processing deficits, but recent findings suggest that non-phonological processes may lie at the root of the association between slow naming speed and poor reading. The hypothesis that rapid naming reflects an independent core deficit in dyslexia is supported by the main findings: (1) some dyslexics are characterized by rapid naming difficulties but intact phonological skills; (2) evidence for an independent association between rapid naming and reading competence in the dyslexic readers, when the effect of phonological skills was controlled; (3) rapid naming and phonological processing measures are not reliably correlated. Recent research also reveals greater predictive power of rapid naming, in particular the inter-item pause time, for high-frequency word reading compared to pseudoword reading in developmental dyslexia. Altogether, the results are more consistent with the view that a phonological component alone cannot account for the rapid naming performance in dyslexia. Rather, rapid naming problems may emerge from the inefficiencies in visual-orthographic processing as well as in phonological processing.

Abstract

In mammals, respiratory-locked hippocampal rhythms are implicated in the scaffolding and transfer of information between sensory and memory networks. These oscillations are entrained by nasal respiration and driven by the olfactory bulb. They then travel to the piriform cortex where they propagate further downstream to the hippocampus and modulate neural processes critical for memory formation. In humans, bypassing nasal airflow through mouth-breathing abolishes these rhythms and impacts encoding as well as recognition processes thereby reducing memory performance. It has been hypothesized that similar behavior should be observed for the consolidation process, the stage between encoding and recognition, were memory is reactivated and strengthened. However, direct evidence for such an effect is lacking in human and non-human animals. Here we tested this hypothesis by examining the effect of respiration on consolidation of episodic odor memory. In two separate sessions, female and male participants encoded odors followed by a one hour awake resting consolidation phase where they either breathed solely through their nose or mouth. Immediately after the consolidation phase, memory for odors was tested. Recognition memory significantly increased during nasal respiration compared to mouth respiration during consolidation. These results provide the first evidence that respiration directly impacts consolidation of episodic events, and lends further support to the notion that core cognitive functions are modulated by the respiratory cycle.

Abstract

Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 second and the ratio of forced expiratory volume in 1 second to forced vital capacity in 48,201 individuals of European ancestry with follow up of the top associations in up to an additional 46,411 individuals. We identified new regions showing association (combined P < 5 × 10(-8)) with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2. Identification of these 16 new loci may provide insight into the molecular mechanisms regulating pulmonary function and into molecular targets for future therapy to alleviate reduced lung function.

Abstract

The efficacy of cardiac repair by stem cell administration relies on a successful functional integration of injected cells into the host myocardium. Safety concerns have been raised about the possibility that stem cells may induce foci of arrhythmia in the ischemic myocardium. In a previous work (36), we showed that human cord blood CD34+ cells, when cocultured on neonatal mouse cardiomyocytes, exhibit excitation-contraction coupling features similar to those of cardiomyocytes, even though no human genes were upregulated. The aims of the present work are to investigate whether human CD34+ cells, isolated after 1 wk of coculture with neonatal ventricular myocytes, possess molecular and functional properties of cardiomyocytes and to discriminate, using a reporter gene system, whether cardiac differentiation derives from a (trans)differentiation or a cell fusion process. Umbilical cord blood CD34+ cells were isolated by a magnetic cell sorting method, transduced with a lentiviral vector carrying the enhanced green fluorescent protein (EGFP) gene, and seeded onto primary cultures of spontaneously beating rat neonatal cardiomyocytes. Cocultured EGFP+/CD34+-derived cells were analyzed for their electrophysiological features at different time points. After 1 wk in coculture, EGFP+ cells, in contact with cardiomyocytes, were spontaneously contracting and had a maximum diastolic potential (MDP) of −53.1 mV, while those that remained isolated from the surrounding myocytes did not contract and had a depolarized resting potential of −11.4 mV. Cells were then resuspended and cultured at low density to identify EGFP+ progenitor cell derivatives. Under these conditions, we observed single EGFP+ beating cells that had acquired an hyperpolarization-activated current typical of neonatal cardiomyocytes (EGFP+ cells, −2.24 ± 0.89 pA/pF; myocytes, −1.99 ± 0.63 pA/pF, at −125 mV). To discriminate between cell autonomous differentiation and fusion, EGFP+/CD34+ cells were cocultured with cardiac myocytes infected with a red fluorescence protein-lentiviral vector; under these conditions we found that 100% of EGFP+ cells were also red fluorescent protein positive, suggesting cell fusion as the mechanism by which cardiac functional features are acquired.

Abstract

The main goal of the present study is to trace the consequences of local and global markedness for the processing of singular and plural nouns. Decompositional models such as proposed by (Pinker (1997); Pinker (1999)) and (Levelt et al. (1999)) predict a lexeme frequency effect and no effects of the frequencies of the singular and the plural forms. Experiments 1 and 4 reveal the expected lexeme frequency effect. Furthermore, in these experiments there are no clear independent effects of the frequencies of the inflected forms. However, the effects of Entropy and Relative Entropy that emerge from these experiments show that in production knowledge of the probabilities of the individual inflected forms do play a role, albeit indirectly. These entropy effects bear witness to the importance of paradigmatic organization of inflected forms in the mental lexicon, both at the level of individual lexemes (Entropy) and at the general level of the class of nouns (Relative Entropy).

Abstract

At least three cognitive brain components are necessary in order for us to be able to produce and comprehend language: a Memory repository for the lexicon, a Unification buffer where lexical information is combined into novel structures, and a Control apparatus presiding over executive function in language. Here we describe the brain networks that support Memory and Unification in semantics. A dynamic account of their interactions is presented, in which a balance between the two components is sought at each word-processing step. We use the theory to provide an explanation of the N400 effect.

Abstract

Human language stands out in the natural world as a biological signal that uses a structured system to combine the meanings of small linguistic units (e.g., words) into larger constituents (e.g., phrases and sentences). However, the physical dynamics of speech (or sign) do not stand in a one-to-one relationship with the meanings listeners perceive. Instead, listeners infer meaning based on their knowledge of the language. The neural readouts of the perceptual and cognitive processes underlying these inferences are still poorly understood. In the present study, we used scalp electroencephalography (EEG) to compare the neural response to phrases (e.g., the red vase) and sentences (e.g., the vase is red), which were close in semantic meaning and had been synthesized to be physically indistinguishable. Differences in structure were well captured in the reorganization of neural phase responses in delta (approximately <2 Hz) and theta bands (approximately 2 to 7 Hz),and in power and power connectivity changes in the alpha band (approximately 7.5 to 13.5 Hz). Consistent with predictions from a computational model, sentences showed more power, more power connectivity, and more phase synchronization than phrases did. Theta–gamma phase–amplitude coupling occurred, but did not differ between the syntactic structures. Spectral–temporal response function (STRF) modeling revealed different encoding states for phrases and sentences, over and above the acoustically driven neural response. Our findings provide a comprehensive description of how the brain encodes and separates linguistic structures in the dynamics of neural responses. They imply that phase synchronization and strength of connectivity are readouts for the constituent structure of language. The results provide a novel basis for future neurophysiological research on linguistic structure representation in the brain, and, together with our simulations, support time-based binding as a mechanism of structure encoding in neural dynamics.

Abstract

Autism is characterized by impairments in reciprocal social interaction and communication, and restricted and sterotyped patterns of interests and activities. Developmental difficulties are apparent before 3 years of age and there is evidence for strong genetic influences most likely involving more than one susceptibility gene. A two-stage genome search for susceptibility loci in autism was performed on 87 affected sib pairs plus 12 non-sib affected relative-pairs, from a total of 99 families identified by an international consortium. Regions on six chromosomes (4, 7, 10, 16, 19 and 22) were identified which generated a multipoint maximum lod score (MLS) > 1. A region on chromosome 7q was the most significant with an MLS of 3.55 near markers D7S530 and D7S684 in the subset of 56 UK affected sib-pair families, and an MLS of 2.53 in all 87 affected sib-pair families. An area on chromosome 16p near the telomere was the next most significant, with an MLS of 1.97 in the UK families, and 1.51 in all families. These results are an important step towards identifying genes predisposing to autism; establishing their general applicability requires further study.

Abstract

Like many other types of memory formation, novel word learning benefits from an offline consolidation period after the initial encoding phase. A previous EEG study has shown that retrieval of novel words elicited more word-like-induced electrophysiological brain activity in the theta band after consolidation [Bakker, I., Takashima, A., van Hell, J. G., Janzen, G., & McQueen, J. M. Changes in theta and beta oscillations as signatures of novel word consolidation. Journal of Cognitive Neuroscience, 27, 1286–1297, 2015]. This suggests that theta-band oscillations play a role in lexicalization, but it has not been demonstrated that this effect is directly caused by the formation of lexical representations. This study used magnetoencephalography to localize the theta consolidation effect to the left posterior middle temporal gyrus (pMTG), a region known to be involved in lexical storage. Both untrained novel words and words learned immediately before test elicited lower theta power during retrieval than existing words in this region. After a 24-hr consolidation period, the difference between novel and existing words decreased significantly, most strongly in the left pMTG. The magnitude of the decrease after consolidation correlated with an increase in behavioral competition effects between novel words and existing words with similar spelling, reflecting functional integration into the mental lexicon. These results thus provide new evidence that consolidation aids the development of lexical representations mediated by the left pMTG. Theta synchronization may enable lexical access by facilitating the simultaneous activation of distributed semantic, phonological, and orthographic representations that are bound together in the pMTG.

Abstract

Mouthings and mouth gestures are omnipresent in Sign Language of the Netherlands (NGT). Mouthings in NGT commonly have their origin in spoken Dutch. We conducted a corpus study to explore how frequent mouthings in fact are in NGT, whether there is variation within and between signs in mouthings, and how frequent temporal reduction occurs in mouthings. Answers to these questions can help us classify mouthings as being specified in the sign lexicon or as being instances of code-blending. We investigated a sample of 20 frequently occurring signs. We found that each sign in the sample co-occurs frequently with a mouthing, usually that of a specific Dutch lexical item. On the other hand, signs show variation in the way they co-occur with mouthings and mouth gestures. By using a relatively large amount of natural data, we succeeded in gaining more insight into the way mouth actions are utilized in sign languages.

Abstract

Dit artikel is de inleiding op het direct hierna volgende (Oonk e.a. 2022) waar een nieuw praktijkmodel over het ontstaan en ontwikkeling van stotteren wordt voorgesteld.

In de dagelijkse praktijk van vooral Nederlandstalige logopedisten (-stottertherapeuten) is tot nu toe veel gebruik gemaakt van het klinische werkmodel van Bertens (1994; 2017). Dit model gaat uit van een primaire neuromusculaire timingsstoornis, welke zich niet alleen uit in het spreken, maar ook in algemene zin aanwezig is. Dit model echter, is aan revisie toe. Volgens de recente literatuur is de algemene aard van die timingstoornis niet bewezen, en zijn er veel vroegere (meer primaire) factoren aantoonbaar van belang bij het ontstaan van stotteren, met name in de genetica en in de neurologie. In dit artikel wordt deze literatuur kort samengevat, alsmede worden enkele recente modellen omschreven. Met name regulatie en terugkoppeling krijgen in recente modellen meer aandacht. Er is geen volledigheid nagestreefd, maar dit artikel is meer een tutoriale opmaat voor het hierna te presenteren model.
(This article serves as an introduction to the accompanying paper, in which a new clinical
model of the origin and development of stuttering is presented (Oonk e.a., 2022).
In their clinical practice, Dutch speech language pathologists still tend to use the
clinical model proposed by Bertens (1994; 2017). This model explains stuttering as de-
veloping from a primary neuromuscular timing deficit, which manifests itself not only
in speech, but in more general behaviour as well. In our opinion, this model needs to be
updated and revised based on current scientific and clinical knowledge. There is littleevidence for the general timing deficit in Bertens’ model and, moreover, several more
fundamental factors, especially those related to genetics and neural processes, that have
an important role in the onset of stuttering have been reported. This paper provides a
review and summary of these recent data, and several newer models are described. An
important aspect of these models is the importance given to processes of regulation
and feedback. An exhaustive overview of the existing literature has not been strived for
but it is hoped that this paper will serve as a useful introduction to the clinical model
presented in the accompanying paper.)

Abstract

The Romance counting system is numerical – with residues of earlier systems whereby each commodity had its own unit of quantification – and decimal. Numeral formations beyond ‘10’ are compounds, combining two or more numerals that are in an arithmetical relation, typically that of addition and multiplication. Formal variation across the (standard) Romance languages and dialects and across historical stages involves the relative sequence of the composing elements, absence or presence of connectors, their synthetic vs. analytic nature, and the degree of grammatical marking. A number of ‘deviant’ numeral formations raise the question of borrowing vs independent development, such as vigesimals (featuring a base ‘20’ instead ‘10’) in certain Romance varieties and the teen and decad formations in Romanian. The other types of numeral in Romance, which derive from the unmarked and consistent cardinals, feature a significantly higher degree of formal complexity and variation involving Latin formants and tend toward analyticity. While Latin features prominently in the Romance counting system as a source of numeral formations and suffixes, it is only in Romance that the inherited decimal system reached its full potential, illustrating its increasing prominence, reflected not only in numerals, but also in language acquisition, sign language, and post-Revolution measuring systems.

Abstract

Managing Director of the Max Planck Institute for Psycholinguistics, founding Director of the Donders Centre for Cognitive Neuroimaging (DCCN, 1999), and professor of Cognitive Neuroscience at Radboud University, all located in Nijmegen, the Netherlands, PETER HAGOORT examines how the brain controls language production and comprehension. He was one of the first to integrate psychological theory and models from neuroscience in an attempt to understand how the human language faculty is instantiated in the brain.

Abstract

Mutations of the FOXP2 gene cause a severe speech and language disorder, providing a molecular window into the neurobiology of language. Individuals with FOXP2 mutations have structural and functional alterations affecting brain circuits that overlap with sites of FOXP2 expression, including regions of the cortex, striatum, and cerebellum. FOXP2 displays complex patterns of expression in the brain, as well as in non-neuronal tissues, suggesting that sophisticated regulatory mechanisms control its spatio-temporal expression. However, to date, little is known about the regulation of FOXP2 or the genomic elements that control its expression. Using chromatin conformation capture (3C), we mapped the human FOXP2 locus to identify putative enhancer regions that engage in long-range interactions with the promoter of this gene. We demonstrate the ability of the identified enhancer regions to drive gene expression. We also show regulation of the FOXP2 promoter and enhancer regions by candidate regulators – FOXP family and TBR1 transcription factors. These data point to regulatory elements that may contribute to the temporal- or tissue-specific expression patterns of human FOXP2. Understanding the upstream regulatory pathways controlling FOXP2 expression will bring new insight into the molecular networks contributing to human language and related disorders.

Abstract

The current paper proposes a frame-based account to conceptual shifts in the countability do-main. We interpret shifts in noun countability as syntactically driven metonymy. Inserting a noun in an incongruent noun phrase, that is combining it with a determiner of the other countability class, gives rise to a re-interpretation of the noun referent. We assume lexical entries to be three-fold frame com-plexes connecting conceptual knowledge representations with language-specific form representations via a lemma level. Empirical data from a lexical decision experiment are presented, that support the as-sumption of such a lemma level connecting perceptual input of linguistic signs to conceptual knowledge.

Abstract

We compared the performance of young (college-aged) and older (50+years) speakers in a single object and a multiple object naming task and assessed their susceptibility to semantic and phonological context effects when producing words amidst semantically or phonologically similar or dissimilar words. In single object naming, there were no performance differences between the age groups. In multiple object naming, we observed significant age-related slowing, expressed in longer gazes to the objects and slower speech. In addition, the direction of the phonological context effects differed for the two groups. The results of a supplementary experiment showed that young speakers, when adopting a slow speech rate, coordinated their eye movements and speech differently from the older speakers. Our results imply that age-related slowing in connected speech is not a direct consequence of a slowing of lexical retrieval processes. Instead, older speakers might allocate more processing capacity to speech monitoring processes, which would slow down their concurrent speech planning processes

Abstract

In recent years, it has been suggested that social robots have potential as tutors and educators for both children and adults. While robots have been shown to be effective in teaching knowledge and skill-based topics, we wish to explore how social robots can be used to tutor a second language to young children. As language learning relies on situated, grounded and social learning, in which interaction and repeated practice are central, social robots hold promise as educational tools for supporting second language learning. This paper surveys the developmental psychology of second language learning and suggests an agenda to study how core concepts of second language learning can be taught by a social robot. It suggests guidelines for designing robot tutors based on observations of second language learning in human–human scenarios, various technical aspects and early studies regarding the effectiveness of social robots as second language tutors.

Abstract

We utilized the N400 effect to investigate the influence of speech register on predictive language processing. Participants listened to long stretches (4 – 15 min) of naturalistic speech from different registers (dialogues, news broadcasts, and read-aloud books), totalling approximately 50,000 words, while the EEG signal was recorded. We estimated the surprisal of words in the speech materials with the aid of a statistical language model in such a manner that it reflected different predictive processing strategies; generic, register-specific, or recency-based. The N400 amplitude was best predicted with register-specific word surprisal, indicating that the statistics of the wider context (i.e., register) influences predictive language processing. Furthermore, adaptation to speech register cannot merely be explained by recency effects; instead, listeners adapt their word anticipations to the presented speech register.

Abstract

There are more than 7,000 languages spoken in the world today1. It has been argued that the natural and social environment of languages drives this diversity. However, a fundamental question is how strong are environmental pressures, and does neutral drift suffice as a mechanism to explain diversification? We estimate the phylogenetic signals of geographic dimensions, distance to water, climate and population size on more than 6,000 phylogenetic trees of 46 language families. Phylogenetic signals of environmental factors are generally stronger than expected under the null hypothesis of no relationship with the shape of family trees. Importantly, they are also—in most cases—not compatible with neutral drift models of constant-rate change across the family tree branches. Our results suggest that language diversification is driven by further adaptive and non-adaptive pressures. Language diversity cannot be understood without modelling the pressures that physical, ecological and social factors exert on language users in different environments across the globe.

Abstract

Older children with online schooling requirements, unsurprisingly, were reported to have increased screen time during the first COVID-19 lockdown in many countries. Here, we ask whether younger children with no similar online schooling requirements also had increased screen time during lockdown. We examined children’s screen time during the first COVID-19 lockdown in a large cohort (n = 2209) of 8-to-36-month-olds sampled from 15 labs across 12 countries. Caregivers reported that toddlers with no online schooling requirements were exposed to more screen time during lockdown than before lockdown. While this was exacerbated for countries with longer lockdowns, there was no evidence that the increase in screen time during lockdown was associated with socio-demographic variables, such as child age and socio-economic status (SES). However, screen time during lockdown was negatively associated with SES and positively associated with child age, caregiver screen time, and attitudes towards children’s screen time. The results highlight the impact of the COVID-19 lockdown on young children’s screen time.

Abstract

Both quality and quantity of speech from the primary caregiver have been found to impact language development. A third aspect of the input has been largely ignored: the number of talkers who provide input. Some infants spend most of their waking time with only one person; others hear many different talkers. Even if the very same words are spoken the same number of times, the pronunciations can be more variable when several talkers pronounce them. Is language acquisition affected by the number of people who provide input? To shed light on the possible link between how many people provide input in daily life and infants’ native vowel discrimination, three age groups were tested: 4-month-olds (before attunement to native vowels), 6-month-olds (at the cusp of native vowel attunement) and 12-month-olds (well attuned to the native vowel system). No relationship was found between talker number and native vowel discrimination skills in 4- and 6-month-olds, who are overall able to discriminate the vowel contrast. At 12 months, we observe a small positive relationship, but further analyses reveal that the data are also compatible with the null hypothesis of no relationship. Implications in the context of infant language acquisition and cognitive development are discussed.

Abstract

Previous work suggests key factors for replicability, a necessary feature for theory
building, include statistical power and appropriate research planning. These factors are examined by analyzing a collection of 12 standardized meta-analyses on language development between birth and 5 years. With a median effect size of Cohen's d= 0.45 and typical sample size of 18 participants, most research is underpowered (range: 6%-99%;
median 44%); and calculating power based on seminal publications is not a suitable strategy.
Method choice can be improved, as shown in analyses on exclusion rates and effect size as a
function of method. The article ends with a discussion on how to increase replicability in both language acquisition studies specifically and developmental research more generally.

Abstract

Memory reprocessing following acquisition enhances memory consolidation. Specifically, neural activity during encoding is thought to be ‘replayed’ during subsequent slow-wave sleep. Such memory replay is thought to contribute to the functional reorganization of neural memory traces. In particular, memory replay may facilitate the exchange of information across brain regions by inducing a reconfiguration of connectivity across the brain. Memory reactivation can be induced by external cues through a procedure known as “targeted memory reactivation”. Here, we analysed data from a published study with auditory cues used to reactivate visual object-location memories during slow-wave sleep. We characterized effects of memory reactivation on brain network connectivity using graph-theory. We found that cue presentation during slow-wave sleep increased global network integration of occipital cortex, a visual region that was also active during retrieval of object locations. Although cueing did not have an overall beneficial effect on the retention of cued versus uncued associations, individual differences in overnight memory stabilization were related to enhanced network integration of occipital cortex. Furthermore, occipital cortex displayed enhanced connectivity with mnemonic regions, namely the hippocampus, parahippocampal gyrus, thalamus and medial prefrontal cortex during cue sound presentation. Together, these results suggest a neural mechanism where cue-induced replay during sleep increases integration of task-relevant perceptual regions with mnemonic regions. This cross-regional integration may be instrumental for the consolidation and long-term storage of enduring memories.

Abstract

In two experiments, we studied the role of frequency information in the production of deverbal adjectives and inflected verbs in Dutch. Naming latencies were triggered in a position-response association task and analysed using stepwise mixed-effects modelling, with subject and word as crossed random effects. The production latency of deverbal adjectives was affected by the cumulative frequencies of their verbal stems, arguing for decomposition and against full listing. However, for the inflected verbs, there was an inhibitory effect of Inflectional Entropy, and a nonlinear effect of Lemma Frequency. Additional effects of Position-specific Neighbourhood Density and Cohort Entropy in both types of words underline the importance of paradigmatic relations in the mental lexicon. Taken together, the data suggest that the word-form level does neither contain full forms nor strictly separated morphemes, but rather morphemes with links to phonologically andin case of inflected verbsmorphologically related word forms.

Abstract

Aesthetic chills, broadly defined as a somatic marker of peak emotional-hedonic responses, are experienced by individuals across a variety of human cultures. Yet individuals vary widely in the propensity of feeling them. These individual differences have been studied in relation to demographics, personality, and neurobiological and physiological factors, but no study to date has explored the genetic etiological sources of variation. To partition genetic and environmental sources of variation in the propensity of feeling aesthetic chills, we fitted a biometrical genetic model to data from 14127 twins (from 8995 pairs), collected by the Netherlands Twin Register. Both genetic and unique environmental factors accounted for variance in aesthetic chills, with heritability estimated at .36 ([.33, .39] 95% CI). We found females more prone than males to report feeling aesthetic chills. However, a test for genotype x sex interaction did not show evidence that heritability differs between sexes. We thus show that the propensity of feeling aesthetic chills is not shaped by nurture alone, but it also reflects underlying genetic propensities.Competing Interest StatementThe authors have declared no competing interest.

Abstract

Human voices play a fundamental role in social communication, and areas of the adult ‘social brain’ show specialization for processing voices and its emotional content (superior temporal sulcus - STS, inferior prefrontal cortex, premotor cortical regions, amygdala and insula [1-8]. However, it is unclear when this specialization develops. Functional magnetic resonance (fMRI) studies suggest the infant temporal cortex does not differentiate speech from music or backward speech [10, 11], but a prior study with functional near infrared spectroscopy revealed preferential activation for human voices in 7-month-olds, in a more posterior location of the temporal cortex than in adults [12]. Yet, the brain networks involved in processing non-speech human vocalizations in early development are still unknown. For this purpose, in the present fMRI study, 3 to 7 month olds were presented with adult non-speech vocalizations (emotionally neutral, emotionally positive and emotionally negative), and non-vocal environmental sounds. Infants displayed significant activation in the anterior portion of the temporal cortex, similarly to adults [1]. Moreover, sad vocalizations modulated the activity of brain regions known to be involved in processing affective stimuli such as the orbitofrontal cortex [13] and insula [7, 8]. These results suggest remarkably early functional specialization for processing human voice and negative emotions.

Abstract

Although many studies have investigated the activation of perceptual representations during language comprehension, to our knowledge only one previous study has directly tested how perceptual features are combined into representations during comprehension. In their classic study, Potter and Faulconer [(1979). Understanding noun phrases. Journal of Verbal Learning and Verbal Behavior, 18, 509–521.] investigated the perceptual representation of adjective-noun combinations. However, their non-orthogonal design did not allow the differentiation between conjunctive vs. disjunctive representations. Using randomized orthogonal designs, we observe evidence for disjunctive perceptual representations when participants represent feature combinations simultaneously (in several experiments; N = 469), and we observe evidence for conjunctive perceptual representations when participants represent feature combinations sequentially (In several experiments; N = 628). Our findings show that the generation of conjunctive representations during comprehension depends on the concatenation of linguistic cues, and thus suggest the construction of elaborate perceptual representations may critically depend on language.

Abstract

Language is the result of two concurrent evolutionary processes: Biological and cultural inheritance. An influential evolutionary hypothesis known as the moving target problem implies inherent limitations on the interactions between our two inheritance streams that result from a difference in pace: The speed of cultural evolution is thought to rule out cognitive adaptation to culturally evolving aspects of language. We examine this hypothesis formally by casting it as as a problem of adaptation in time-varying environments. We present a mathematical model of biology-culture co-evolution in finite populations: A generalisation of the Moran process, treating co-evolution as coupled non-independent Markov processes, providing a general formulation of the moving target hypothesis in precise probabilistic terms. Rapidly varying culture decreases the probability of biological adaptation. However, we show that this effect declines with population size and with stronger links between biology and culture: In realistically sized finite populations, stochastic effects can carry cognitive specialisations to fixation in the face of variable culture, especially if the effects of those specialisations are amplified through cultural evolution. These results support the view that language arises from interactions between our two major inheritance streams, rather than from one primary evolutionary process that dominates another. © 2018 The Author(s).

Abstract

Purpose

Although haploinsufficiency of ANKRD11 is among the most common genetic causes of neurodevelopmental disorders, the role of rare ANKRD11 missense variation remains unclear. We characterized clinical, molecular, and functional spectra of ANKRD11 missense variants.
Methods

We collected clinical information of individuals with ANKRD11 missense variants and evaluated phenotypic fit to KBG syndrome. We assessed pathogenicity of variants through in silico analyses and cell-based experiments.
Results

We identified 20 unique, mostly de novo, ANKRD11 missense variants in 29 individuals, presenting with syndromic neurodevelopmental disorders similar to KBG syndrome caused by ANKRD11 protein truncating variants or 16q24.3 microdeletions. Missense variants significantly clustered in repression domain 2 at the ANKRD11 C-terminus. Of the 10 functionally studied missense variants, 6 reduced ANKRD11 stability. One variant caused decreased proteasome degradation and loss of ANKRD11 transcriptional activity.
Conclusion

Our study indicates that pathogenic heterozygous ANKRD11 missense variants cause the clinically recognizable KBG syndrome. Disrupted transrepression capacity and reduced protein stability each independently lead to ANKRD11 loss-of-function, consistent with haploinsufficiency. This highlights the diagnostic relevance of ANKRD11 missense variants, but also poses diagnostic challenges because the KBG-associated phenotype may be mild and inherited pathogenic ANKRD11 (missense) variants are increasingly observed, warranting stringent variant classification and careful phenotyping.

Abstract

Prosodic breaks (PBs) can indicate a sentence’s syntactic structure. Event-related brain potentials (ERPs) are an excellent way to study auditory sentence processing, since they provide an on-line measure across a complete sentence, in contrast to other on- and off-line methods. ERPs for the first time allowed investigating the processing of a PB itself. PBs reliably elicit a closure positive shift (CPS). We first review several studies on the CPS, leading to the conclusion that it is elicited by abstract structuring or phrasing of the input. Then we review ERP findings concerning the role of PBs in sentence processing as indicated by ERP components like the N400, P600 and LAN. We focus on whether and how PBs can (help to) disambiguate locally ambiguous sentences. Differences in results between different studies can be related to differences in items, initial parsing preferences and tasks. Finally, directions for future research are discussed.

Abstract

We investigated whether listeners are sensitive to (mis)matching accentuation patterns with respect to contrasts in the linguistic and visual context, using Event-Related Potentials. We presented participants with displays of two pictures followed by a spoken reference to one of these pictures (e.g., “the red ball”). The referent was contrastive with respect to the linguistic context (utterance in the previous trial: e.g., “the blue ball”) or with respect to the visual context (other picture in the display; e.g., a display with a red ball and a blue ball). The spoken reference carried a pitch accent on the noun (“the red BALL”) or on the adjective (“the RED ball”), or an intermediate (‘neutral’) accentuation. For the linguistic context, we found evidence for the Missing Accent Hypothesis: Listeners showed processing difficulties, in the form of increased negativities in the ERPs, for missing accents, but not for superfluous accents. ‘Neutral’ or intermediate accents were interpreted as ‘missing’ accents when they occurred late in the referential utterance, but not when they occurred early. For the visual context, we found evidence for the Missing Accent Hypothesis for a missing accent on the adjective (an increase in negativity in the ERPs) and a superfluous accent on the noun (no effect). However, a redundant color adjective (e.g., in the case of a display with a red ball and a red hat) led to less processing problems when the adjective carried a pitch accent.

Abstract

Rapid response latencies in conversation suggest that responders start planning before the ongoing turn is finished. Indeed, an earlier EEG study suggests that listeners start planning their responses to questions as soon as they can (Bögels, S., Magyari, L., & Levinson, S. C. (2015). Neural signatures of response planning occur midway through an incoming question in conversation. Scientific Reports, 5, 12881). The present study aimed to (1) replicate this early planning effect and (2) investigate whether such early response planning incurs a cost on participants’ concurrent comprehension of the ongoing turn. During the experiment participants answered questions from a confederate partner. To address aim (1), the questions were designed such that response planning could start either early or late in the turn. Our results largely replicate Bögels et al. (2015) showing a large positive ERP effect and an oscillatory alpha/beta reduction right after participants could have first started planning their verbal response, again suggesting an early start of response planning. To address aim (2), the confederate's questions also contained either an expected word or an unexpected one to elicit a differential N400 effect, either before or after the start of response planning. We hypothesized an attenuated N400 effect after response planning had started. In contrast, the N400 effects before and after planning did not differ. There was, however, a positive correlation between participants' response time and their N400 effect size after planning had started; quick responders showed a smaller N400 effect, suggesting reduced attention to comprehension and possibly reduced anticipatory processing. We conclude that early response planning can indeed impact comprehension processing.

Abstract

The present study addresses the question whether accentuation and prosodic phrasing can have a similar function, namely, to group words in a sentence together. Participants listened to locally ambiguous sentences containing object- and subject-control verbs while ERPs were measured. In Experiment 1, these sentences contained a prosodic break, which can create a certain syntactic grouping of words, or no prosodic break. At the disambiguation, an N400 effect occurred when the disambiguation was in conflict with the syntactic grouping created by the break. We found a similar N400 effect without the break, indicating that the break did not strengthen an already existing preference. This pattern held for both object- and subject-control items. In Experiment 2, the same sentences contained a break and a pitch accent on the noun following the break. We argue that the pitch accent indicates a broad focus covering two words [see Gussenhoven, C. On the limits of focus projection in English. In P. Bosch & R. van der Sandt (Eds.), Focus: Linguistic, cognitive, and computational perspectives. Cambridge: University Press, 1999], thus grouping these words together. For object-control items, this was semantically possible, which led to a “good-enough” interpretation of the sentence. Therefore, both sentences were interpreted equally well and the N400 effect found in Experiment 1 was absent. In contrast, for subject-control items, a corresponding grouping of the words was impossible, both semantically and syntactically, leading to processing difficulty in the form of an N400 effect and a late positivity. In conclusion, accentuation can group words together on the level of information structure, leading to either a semantically “good-enough” interpretation or a processing problem when such a semantic interpretation is not possible.

Abstract

The Mayan languages Tzeltal and Yucatec have large form classes of “dispositional” roots which lexicalize spatial properties such as orientation, support/suspension/blockage of motion, and configurations of parts of an entity with respect to other parts. But speakers of the two languages deploy this common lexical resource quite differently. The roots are used in both languages to convey dispositional information (e.g., answering “how” questions), but Tzeltal speakers also use them in canonical locative descriptions (e.g., answering “where” questions), whereas Yucatec speakers only use dispositionals in locative predications when prompted by the context to focus on dispositional properties. We describe the constructions used in locative and dispositional descriptions in response to two different picture stimuli sets. Evidence against the proposal that Tzeltal uses dispositionals to compensate for its single, semantically generic preposition (Brown 1994; Grinevald 2006) comes from the finding that Tzeltal speakers use relational spatial nominals in the “Ground phrase” — the expression of the place at which an entity is located — about as frequently as Yucatec speakers. We consider several alternative hypotheses, including a possible larger typological difference that leads Tzeltal speakers, but not Yucatec speakers, to prefer “theme-specific” verbs not just in locative predications, but in any predication involving a theme argument.

Abstract

We examine universals and crosslinguistic variation in constraints on event segmentation. Previous typological studies have focused on segmentation into syntactic (Pawley 1987) or intonational units (Givón 1991). We argue that the correlation between such units and semantic/conceptual event representations is language-specific. As an alternative, we introduce the MACRO-EVENT PROPERTY (MEP): a construction has the MEP if it packages event representations such that temporal operators necessarily have scope over all subevents. A case study on the segmentation of motion events into macro-event expressions in eighteen genetically and typologically diverse languages has produced evidence of two types of design principles that impact motion-event segmentation: language-specific lexicalization patterns and universal constraints on form-to-meaning mapping.

Abstract

In 2016, the University of Bordeaux ran a competition within the local neuroscience community to find a
name for its new neuroscience building. The name of Paul Broca, who was born nearby in 1824, was chosen
in honour of his origins and his contributions to neuroscience. Recently, however, a debate has been ignited
about the appropriateness of this choice, given Broca’s endorsement of physiological anthropology. At a time
when academic institutions worldwide are revising their curricula to better reflect the contributions of pre-
viously overlooked groups, how should we respond when the views of the ‘founding fathers’ of neurology
clash with those of society today?

Abstract

This Field Manual entry has been superceded by the 2008 version: https://doi.org/10.17617/2.492932

Abstract

Individuals vary in how they produce speech. This variability affects both the segments (vowels and consonants) and the suprasegmental properties of their speech (prosody). Previous literature has demonstrated that listeners can adapt to variability in how different talkers pronounce the segments of speech. This study shows that listeners can also adapt to variability in how talkers produce lexical stress. Experiment 1 demonstrates a selective adaptation effect in lexical stress perception: repeatedly hearing Dutch trochaic words biased perception of a subsequent lexical stress continuum towards more iamb responses. Experiment 2 demonstrates a recalibration effect in lexical stress perception: when ambiguous suprasegmental cues to lexical stress were disambiguated by lexical orthographic context as signaling a trochaic word in an exposure phase, Dutch participants categorized a subsequent test continuum as more trochee-like. Moreover, the selective adaptation and recalibration effects generalized to novel words, not encountered during exposure. Together, the experiments demonstrate that listeners also flexibly adapt to variability in the suprasegmental properties of speech, thus expanding our understanding of the utility of listener adaptation in speech perception. Moreover, the combined outcomes speak for an architecture of spoken word recognition involving abstract prosodic representations at a prelexical level of analysis.

Abstract

This psychoacoustic study provides behavioral evidence that neural entrainment in the theta range (3-9 Hz) causally shapes speech perception. Adopting the ‘rate normalization’ paradigm (presenting compressed carrier sentences followed by uncompressed target words), we show that uniform compression of a speech carrier to syllable rates inside the theta range influences perception of subsequent uncompressed targets, but compression outside theta range does not. However, the influence of carriers – compressed outside theta range – on target perception is salvaged when carriers are ‘repackaged’ to have a packet rate inside theta. This suggests that the brain can only successfully entrain to syllable/packet rates within theta range, with a causal influence on the perception of subsequent speech, in line with recent neuroimaging data. Thus, this study points to a central role for sustained theta entrainment in rate normalization and contributes to our understanding of the functional role of brain oscillations in speech perception.

Abstract

Recently, the world’s attention was caught by an audio clip that was perceived as “Laurel” or “Yanny”. Opinions were sharply split: many could not believe others heard something different from their perception. However, a crowd-source experiment with >500 participants shows that it is possible to make people hear Laurel, where they previously heard Yanny, by manipulating preceding acoustic context. This study is not only the first to reveal within-listener variation in Laurel/Yanny percepts, but also to demonstrate contrast effects for global spectral information in larger frequency regions. Thus, it highlights the intricacies of human perception underlying these social media phenomena.

Abstract

Speakers adjust their voice when talking in noise (known as Lombard speech), facilitating speech comprehension. Recent neurobiological models of speech perception emphasize the role of amplitude modulations in speech-in-noise comprehension, helping neural oscillators to ‘track’ the attended speech. This study tested whether talkers produce more pronounced amplitude modulations in noise. Across four different corpora, modulation spectra showed greater power in amplitude modulations below 4 Hz in Lombard speech compared to matching plain speech. This suggests that noise-induced speech contains more pronounced amplitude modulations, potentially helping the listening brain to entrain to the attended talker, aiding comprehension.

Abstract

Relational grammar was proposed in Suppes (1976) as a semantical grammar for natural language. Fragments considered so far are restricted to distributive notions. In this article, relational grammar is extended to collective notions.

Abstract

Reprinted from Bowerman, M. & Choi, S. (2003). Space under construction: Language-specific spatial categorization in first language acquisition. In D. Gentner & S. Goldin-Meadow (Eds.), Language in Mind (pp. 387-427). Cambridge: MIT Press.

Abstract

Among children’s earliest spatial words are topological forms like ‘in’ and ‘on’. Although these forms name spatial relationships, they also presuppose a classification of ground objects into entities such as “containers” and “surfaces”; hence their relevance for a volume on “spatial entities”. Traditionally, researchers have assumed that semantic categories of space are universal, reflecting a human way of nonlinguistically perceiving and cognizing space. But, as this chapter discusses, spatial categories in fact differ strikingly across languages, and children begin to home in on language-specific classifications extremely early, before age two. Learners do not, it seems, draw only on purely nonlinguistic spatial concepts; they can also actively construct spatial categories on the basis of the linguistic input. Evidence is drawn primarily from research on children learning Korean vs. English.

Abstract

Reprinted from: Bowerman, M. & Choi, S. (2001). Shaping meanings for language: Universal and language specific in the acquisition of spatial semantic categories. In M. Bowerman & S.L. Levinson (Eds.), Language acquisition and conceptual development (pp. 475-511). Cambridge: Cambridge University Press.

Abstract

This study reports three experiments on how children learning Mandarin Chinese comprehend and use aspect markers. These experiments examine the role of lexical aspect in children's acquisition of grammatical aspect. Results provide converging evidence for children's early sensitivity to (1) the association between atelic verbs and the imperfective aspect markers zai, -zhe, and -ne, and (2) the association between telic verbs and the perfective aspect marker -le. Children did not show a sensitivity in their use or understanding of aspect markers to the difference between stative and activity verbs or between semelfactive and activity verbs. These results are consistent with Slobin's (1985) basic child grammar hypothesis that the contrast between process and result is important in children's early acquisition of temporal morphology. In contrast, they are inconsistent with Bickerton's (1981, 1984) language bioprogram hypothesis that the distinctions between state and process and between punctual and nonpunctual are preprogrammed into language learners. We suggest new ways of looking at the results in the light of recent probabilistic hypotheses that emphasize the role of input, prototypes and connectionist representations.

Abstract

Aim

To examine the phenomenology of stuttering across the lifespan in the largest prospective cohort to date.
Method

Participants aged 7 years and older with a history of developmental stuttering were recruited. Self-reported phenotypic data were collected online including stuttering symptomatology, co-occurring phenotypes, genetic predisposition, factors associated with stuttering severity, and impact on anxiety, education, and employment.
Results

A total of 987 participants (852 adults: 590 males, 262 females, mean age 49 years [SD = 17 years 10 months; range = 18–93 years] and 135 children: 97 males, 38 females, mean age 11 years 4 months [SD = 3 years; range = 7–17 years]) were recruited. Stuttering onset occurred at age 3 to 6 years in 64.0%. Blocking (73.2%) was the most frequent phenotype; 75.9% had sought stuttering therapy and 15.5% identified as having recovered. Half (49.9%) reported a family history. There was a significant negative correlation with age for both stuttering frequency and severity in adults. Most were anxious due to stuttering (90.4%) and perceived stuttering as a barrier to education and employment outcomes (80.7%).
Interpretation

The frequent persistence of stuttering and the high proportion with a family history suggest that stuttering is a complex trait that does not often resolve, even with therapy. These data provide new insights into the phenotype and prognosis of stuttering, information that is critically needed to encourage the development of more effective speech therapies.

Abstract

Previous studies have shown a significant association between reading skills and the performance on visuo-motor tasks. In order to clarify whether reading and writing skills modulate non-linguistic domains, we investigated the performance of two literacy groups on a visuo-motor integration task with non-linguistic stimuli. Twenty-one illiterate participants and twenty matched literate controls were included in the experiment. Subjects were instructed to use the right or the left index finger to point to and touch a randomly presented target on the right or left side of a touch screen. The results showed that the literate subjects were significantly faster in detecting and touching targets on the left compared to the right side of the screen. In contrast, the presentation side did not affect the performance of the illiterate group. These results lend support to the idea that having acquired reading and writing skills, and thus a preferred left-to-right reading direction, influences visual scanning. (JINS, 2007, 13, 359–364

Abstract

In this study, we systematically review the scientific literature on the effect of color on object recognition. Thirty-five independent experiments, comprising 1535 participants, were included in a meta-analysis. We found a moderate effect of color on object recognition (d = 0.28). Specific effects of moderator variables were analyzed and we found that color diagnosticity is the factor with the greatest moderator effect on the influence of color in object recognition; studies using color diagnostic objects showed a significant color effect (d = 0.43), whereas a marginal color effect was found in studies that used non-color diagnostic objects (d = 0.18). The present study did not permit the drawing of specific conclusions about the moderator effect of the object recognition task; while the meta-analytic review showed that color information improves object recognition mainly in studies using naming tasks (d = 0.36), the literature review revealed a large body of evidence showing positive effects of color information on object recognition in studies using a large variety of visual recognition tasks. We also found that color is important for the ability to recognize artifacts and natural objects, to recognize objects presented as types (line-drawings) or as tokens (photographs), and to recognize objects that are presented without surface details, such as texture or shadow. Taken together, the results of the meta-analysis strongly support the contention that color plays a role in object recognition. This suggests that the role of color should be taken into account in models of visual object recognition.

Abstract

In the present study, the authors explore in detail the level of visual object recognition at which perceptual color information improves the recognition of color diagnostic and noncolor diagnostic objects. To address this issue, 3 object recognition tasks, with different cognitive demands, were designed: (a) an object verification task; (b) a category verification task; and (c) a name verification task. They found that perceptual color information improved color diagnostic object recognition mainly in tasks for which access to the semantic knowledge about the object was necessary to perform the task; that is, in category and name verification. In contrast, the authors found that perceptual color information facilitates noncolor diagnostic object recognition when access to the object’s structural description from long-term memory was necessary—that is, object verification. In summary, the present study shows that the role of perceptual color information in object recognition is dependent on color diagnosticity

Abstract

n casual conversations, words often lack segments. This study investigates whether listeners rely on their experience with reduced word pronunciation variants during the processing of single segment reduction. We tested three groups of listeners in a lexical decision experiment with French words produced either with or without word-medial schwa (e.g., /ʀəvy/ and /ʀvy/ for revue). Participants also rated the relative frequencies of the two pronunciation variants of the words. If the recognition accuracy and reaction times for a given listener group correlate best with the frequencies of occurrence holding for that given listener group, recognition is influenced by listeners’ exposure to these variants. Native listeners' relative frequency ratings correlated well with their accuracy scores and RTs. Dutch advanced learners' accuracy scores and RTs were best predicted by their own ratings. In contrast, the accuracy and RTs from Dutch beginner learners of French could not be predicted by any relative frequency rating; the rating task was probably too difficult for them. The participant groups showed behaviour reflecting their difference in experience with the pronunciation variants. Our results strongly suggest that listeners store the frequencies of occurrence of pronunciation variants, and consequently the variants themselves

Abstract

Natural language contains many examples of sound‐symbolism, where the form of the word carries information about its meaning. Such systematicity is more prevalent in the words children acquire first, but arbitrariness dominates during later vocabulary development. Furthermore, systematicity appears to promote learning category distinctions, which may become more important as the vocabulary grows. In this study, we tested the relative costs and benefits of sound‐symbolism for word learning as vocabulary size varies. Participants learned form‐meaning mappings for words which were either congruent or incongruent with regard to sound‐symbolic relations. For the smaller vocabulary, sound‐symbolism facilitated learning individual words, whereas for larger vocabularies sound‐symbolism supported learning category distinctions. The changing properties of form‐meaning mappings according to vocabulary size may reflect the different ways in which language is learned at different stages of development.

Abstract

A study was conducted to test the effect of two different forms of real-time visual feedback on expressive percussion performance. Conservatory percussion students performed imitations of recorded teacher performances while receiving either high-level feedback on the expressive style of their performances, low-level feedback on the timing and dynamics of the performed notes, or no feedback. The high-level feedback was based on a Bayesian analysis of the performances, while the low-level feedback was based on the raw participant timing and dynamics data. Results indicated that neither form of feedback led to significantly smaller timing and dynamics errors. However, high-level feedback did lead to a higher proficiency in imitating the expressive style of the target performances, as indicated by a probabilistic measure of expressive style. We conclude that, while potentially disruptive to timing processes involved in music performance due to extraneous cognitive load, high-level visual feedback can improve participant imitations of expressive performance features.

Abstract

This study investigates whether listeners' familiarity with an intonation contour affects speech processing. In three experiments, Dutch participants heard Dutch sentences with normal intonation contours and with unfamiliar ones and performed word-monitoring, lexical decision, or semantic categorisation tasks (the latter two with cross-modal identity priming). The unfamiliar intonation contour slowed down participants on all tasks, which demonstrates that an unfamiliar intonation contour has a robust detrimental effect on speech processing. Since cross-modal identity priming with a lexical decision task taps into lexical access, this effect obtained in this task suggests that an unfamiliar intonation contour hinders lexical access. Furthermore, results from the semantic categorisation task show that the effect of an uncommon intonation contour is long-lasting and hinders subsequent processing. Hence, intonation not only contributes to utterance meaning (emotion, sentence type, and focus), but also affects crucial aspects of the speech comprehension process and is more important than previously thought.

Abstract

Despite their relatedness, Dutch and German differ in the interpretation of a particular intonation contour, the hat pattern. In the literature, this contour has been described as neutral for Dutch, and as contrastive for German. A recent study supports the idea that Dutch listeners interpret this contour neutrally, compared to the contrastive interpretation of a lexically identical utterance realised with a double peak pattern. In particular, this study showed shorter lexical decision latencies to visual targets (e.g., PELIKAAN, “pelican”) following a contrastively related prime (e.g., flamingo, “flamingo”) only when the primes were embedded in sentences with a contrastive double peak contour, not in sentences with a neutral hat pattern. The present study replicates Experiment 1a of Braun and Tagliapietra (2009) with German learners of Dutch. Highly proficient learners of Dutch differed from Dutch natives in that they showed reliable priming effects for both intonation contours. Thus, the interpretation of intonational meaning in L2 appears to be fast, automatic, and driven by the associations learned in the native language.

Abstract

This paper investigated how foreign-accented stress cues affect on-line speech comprehension in British speakers of English. While unstressed English vowels are usually reduced to /@/, Dutch speakers of English only slightly centralize them. Speakers of both languages differentiate stress by suprasegmentals (duration and intensity). In a cross-modal priming experiment, English listeners heard sentences ending in monosyllabic prime fragments—produced by either an English or a Dutch speaker of English—and performed lexical decisions on visual targets. Primes were either stress-matching (“ab” excised from absurd), stress-mismatching (“ab” from absence), or unrelated (“pro” from profound) with respect to the target (e.g., ABSURD). Results showed a priming effect for stress-matching primes only when produced by the English speaker, suggesting that vowel quality is a more important cue to word stress than suprasegmental information. Furthermore, for visual targets with word-initial secondary stress that do not require vowel reduction (e.g., CAMPAIGN), resembling the Dutch way of realizing stress, there was a priming effect for both speakers. Hence, our data suggest that Dutch-accented English is not harder to understand in general, but it is in instances where the language-specific implementation of lexical stress differs across languages.

Abstract

This paper investigates stress assignment in Dutch aphasic patients in non-word repetition, as well as in real-word and non-word reading. Performance on the non-word reading task was similar for the aphasic patients and the control group, as mainly regular stress was assigned to the targets. However, there were group differences on the real-word reading and non-word repetition tasks. Unlike the non-brain-damaged group, the patients showed a strong regularization tendency in their repetition of irregular patterns. The patients’ stress error patterns suggest an impairment in retention or retrieval of targets with irregular stress patterns. Limited verbal short-term memory is proposed as a possible underlying cause for the stress difficulties.

Abstract

Subject–verb agreement errors are common in sentence production. Many studies have used experimental paradigms targeting the production of subject–verb agreement from a sentence preamble (The key to the cabinets) and eliciting verb errors (… *were shiny). Through reanalysis of previous data (50 experiments; 102,369 observations), we show that this paradigm also results in many errors in preamble repetition, particularly of local noun number (The key to the *cabinet). We explore the mechanisms of both errors in parallelism in producing syntax (PIPS), a model in the Gradient Symbolic Computation framework. PIPS models sentence production using a continuous-state stochastic dynamical system that optimizes grammatical constraints (shaped by previous experience) over vector representations of symbolic structures. At intermediate stages in the computation, grammatical constraints allow multiple competing parses to be partially activated, resulting in stable but transient conjunctive blend states. In the context of the preamble completion task, memory constraints reduce the strength of the target structure, allowing for co-activation of non-target parses where the local noun controls the verb (notional agreement and locally agreeing relative clauses) and non-target parses that include structural constituents with contrasting number specifications (e.g., plural instead of singular local noun). Simulations of the preamble completion task reveal that these partially activated non-target parses, as well the need to balance accurate encoding of lexical and syntactic aspects of the prompt, result in errors. In other words: Because sentence processing is embedded in a processor with finite memory and prior experience with production, interference from non-target production plans causes errors.

Abstract

Contrast coding in regression models, including mixed-effect models, changes what the terms in the model mean.
In particular, it determines whether or not model terms should be interpreted as main effects. This paper
highlights how opaque descriptions of contrast coding have affected the field of psycholinguistics. We begin with
a reproducible example in R using simulated data to demonstrate how incorrect conclusions can be made from
mixed models; this also serves as a primer on contrast coding for statistical novices. We then present an analysis
of 3384 papers from the field of psycholinguistics that we coded based upon whether a clear description of
contrast coding was present. This analysis demonstrates that the majority of the psycholinguistic literature does
not transparently describe contrast coding choices, posing an important challenge to reproducibility and replicability in our field.