Publications

Abstract

This chapter introduces the origins and development of our current anatomical terminology. It scrutinizes the historical evolution and etymological significance of the over 1900 official anatomical terms in the current nomenclature, underscoring their impact on the contemporary comprehension of cognitive neuroanatomy. The chapter traces unification efforts from the Basel Nomina Anatomica in 1895 to the 1998 Terminologia Anatomica, noting challenges arising from outdated terminology in light of recent anatomical advancements.

Highlighting the influence of terminologies on interpretations of brain anatomy, the chapter explores several anatomical mapping methods such as surface, sectional, connectional, and functional anatomy. It illuminates discrepancies and controversies, exemplified by divergent interpretations of the number of brain lobes and the definitions of 'Broca' and 'Wernicke' areas.

The chapter explores anatomical terms' historical and cultural underpinnings, encompassing mythonyms, eponyms, and cultural influences on nomenclature. It critically examines the implications of these terminologies on contemporary research and shows that Large Language Models mirror these discrepancies. It underscores the need for more inclusive and culturally sensitive approaches in anatomical education.

Lastly, we advocate for updating anatomical nomenclature, suggesting that a deeper understanding of these terminologies could provide insights and aid in resolving ongoing debates in the field. This examination sheds light on historical knowledge and emphasizes the dynamic interplay between language, culture, and anatomy in shaping our comprehension of the neurobiology of the brain and how we navigate neuroanatomy in the 21st century.

Abstract

The human brain is an intricate network of cortical regions interconnected by white matter pathways, dynamically supporting cognitive functions. While cortical asymmetries have been consistently reported, the asymmetry of white matter connections remains less explored. This chapter provides a brief overview of asymmetries observed at the cortical, subcortical, cytoarchitectural, and receptor levels before exploring the detailed connectional anatomy of the human brain. It thoroughly examines the lateralization and interindividual variability of 56 distinct white matter tracts, offering a comprehensive review of their structural characteristics and interindividual variability. Additionally, we provide an extensive update on the asymmetry of a wide range of white matter tracts using high-resolution data from the Human Connectome Project (7T HCP www.humanconnectome.org). Future research and advanced quantitative analyses are crucial to understanding fully how asymmetry contributes to interindividual variability. This comprehensive exploration enhances our understanding of white matter organization and its potential implications for brain function.

Abstract

The brain is the most magnificent structure, and we are only at the cusp of unraveling some of its complexity. Neuroanatomy is the best tool to map the brain's structural complexity. As such, neuroanatomy is not just an academic exercise; it serves our fundamental understanding of the neurobiology of cognition and improves clinical practice. A deepened anatomical understanding has advanced our conceptual grasp of the evolution of the brain, interindividual variability of cognition in health and disease, and the conceptual shift toward the emergence of cognition. For the past 20 years, diffusion imaging tractography has dramatically facilitated these advances by enabling the study of the delicate networks that orchestrate brain processes (for review, see Thiebaut de Schotten and Forkel, 2022). Several steps are consistent across all studied populations and brain states (health/disease) when analyzing tractography data. We discuss various considerations for dissections across populations and give practical tips on common pitfalls and features to improve the visualization of the dissections. We briefly discuss specific considerations for manual dissections in nonhuman primates. Lastly, we provide an atlas of regions of interest (ROIs) for the most commonly delineated white matter connections in the human brain.

Abstract

As lexicalized depictions, ideophones (also known as expressives or mimetics) differ fundamentally from other words both in the kinds of meanings they represent and the ways in which they represent them. This can make them difficult to capture using traditional methods for language description and documentation. We review some of the new and experimental techniques that have been used to elicit, describe, and analyse ideophones, and discuss how these can be used to address some of the unique challenges ideophones pose. They include stimulus-based elicitation; multimodal folk definitions; hybrid modes of analysis (combining images and text); and new ways of compiling and presenting multimodal ideophone corpora. We also review psycholinguistic methods for exploring the sensory properties of words and the organisation of the lexicon, such as sensory ratings and similarity judgment tasks, and discuss how these can contribute to our understanding of ideophone lexicons. Crucial to our approach is the combination of insights from multiple sources, the exploitation of polysemiotic resources (combining multiple modes of meaning making), and the integration of etic and emic perspectives. The discussion is structured around three key challenges: collecting ideophones, unravelling their slippery semantics, and representing them in ways that do justice to their special semiotic properties. The days when ideophones were just footnotes in grammars are long past. With more and more researchers working to document ideophones in languages around the world, and increasing interest in iconicity from across the language sciences, now is an excellent time to rethink the toolkit of documentary linguistics to make sure it can optimally deal with language in all its semiotic diversity.

Abstract

By studying communicative interactions between humans, we can investigate the basic processes underlying the evolution of language, including how humans manage to communicate in the first place, how they form novel conventions, how they create grammatical structure, and subsequent changes to their conventions and grammar. Communication experiments, which involve interactions between two or more human participants in artificial settings, are a useful method for addressing these questions within a controlled environment. These experiments can help researchers with teasing apart the effects of different variables on the emergence of language, which are typically confounded in naturalistic settings. In this chapter, we first briefly review the history of communication paradigms. We then summarize the procedures, designs, and typical measures that characterize communication experiments. Finally, we discuss the theoretical limitations and methodological challenges of using such paradigms and propose some ways forward.

Abstract

Brain tumors are classified as rare diseases, with an annual occurrence of 300,000 cases and account for an annual loss of 241,000 lives, highlighting their devastating nature. Recent advancements in diagnosis and treatment have significantly improved the management and care of brain tumors. This chapter provides an overview of the common types of primary brain tumors affecting language functions—gliomas and meningiomas. Techniques for identifying and mapping critical language areas, including the white matter language system, such as awake brain tumor surgery and diffusion-weighted tractography, are pivotal for understanding language localization and informing personalized treatment approaches. Numerous studies have demonstrated that gliomas in the dominant hemisphere can lead to (often subtle) impairments across various cognitive domains, with a particular emphasis on language. Recently, increased attention has been directed toward (nonverbal) cognitive deficits in patients with gliomas in the nondominant hemisphere, as well as cognitive outcomes in patients with meningiomas, a group historically overlooked. A patient-tailored approach to language and cognitive functions across the pre-, intra-, and postoperative phases is mandatory for brain tumor patients to preserve quality of life. Continued follow-up studies, in conjunction with advanced imaging techniques, are crucial for understanding the brain's potential for neuroplasticity and optimizing patient outcomes.

Abstract

Left-right asymmetry is an important aspect of human brain organization for functions including language and hand motor control, which can be altered in some psychiatric traits. The last five years have seen rapid advances in the identification of specific genes linked to variation in asymmetry of the human brain and/or handedness. These advances have been driven by a new generation of large-scale genome-wide association studies, carried out in samples ranging from roughly 16,000 to over 1.5 million participants. The implicated genes tend to be most active in the embryonic and fetal brain, consistent with early developmental patterning of brain asymmetry. Several of the genes encode components of microtubules, or other microtubule-associated proteins. Microtubules are key elements of the internal cellular skeleton (cytoskeleton). A major challenge remains to understand how these genes affect, or even induce, the brain’s left-right axis. Several of the implicated genes have also been associated with psychiatric or neurological disorders, and polygenic dispositions to autism and schizophrenia have been associated with structural brain asymmetry. Knowledge of developmental mechanisms that lead to hemispheric specialization may ultimately help to define etiologic subtypes of brain disorders.

Abstract

Sign languages—the conventional languages of deaf communities—have been considered to provide a window into answering some questions regarding language emergence and evolution. In particular, iconicity, defined as the ‘existence of a structure-preserving mapping between mental models of linguistic form and meaning’, is generally regarded as a precursor to the arbitrary and segmental categorical structures found in spoken languages. However, iconic structures are omnipresent in sign languages at all levels of linguistic organization. Thus, there is a necessity for a more nuanced understanding of iconicity and its trajectory in language evolution. In this chapter, we outline different quantitative and qualitative methods to study iconicity and how one can operationalize them at lexical and discourse levels to investigate the role of iconicity in the evolution of sign languages.

Abstract

Bioacoustics is an interdisciplinary science; it concerns aspects of communication through sound in animals, including humans. Within language evolution research, bioacoustics is particularly relevant to address questions about the origins and evolution of speech. Areas of bioacoustics research include the perception and production of acoustic signals, their transmission in the environment, and the neural and anatomical correlates that determine and influence communication. Here, we review the tools needed to conduct bioacoustics research, from initial methodological choices to instrument choice, based on critical features needed for data collection in the field. We discuss key methodological choices in sound recording and processing raw data from a data collection campaign. We provide recommendations for the recording and use of acoustic signals. We discuss analysis techniques, focusing exclusively on rhythm in animal vocalizations. We conclude by stressing the potential for multidisciplinary collaborations, and highlighting key areas where these collaborations could happen.